2025-02-21T11:03:54-06:00 2024-09-30 930623286 ALDRICH CPAS AND ADVISORS LLP 680 HAWTHORNE AVE SE 140 SALEM OR 97301 990 2023-10-01 330189397 VETERANS MEDICAL RESEARCH FOUNDATION OF SAN DIEGO VETE 8586423070 3350 LA JOLLA VILLAGE DR BLDG 13 SAN DIEGO CA 92161 MARIA SITTMANN EXECUTIVE DIRECTOR/CEO 8586423070 2025-02-11 1 1 RYAN M JOHNSON CPA P01048788 5035857774 2025-02-11 2023 2025-03-06 01:10:19Z MARIA SITTMANN 3350 LA JOLLA VILLAGE DR BLDG 13 SAN DIEGO CA 92161 16594911 0 X WWW.VMRF.ORG X 1989 CA TO ENHANCE THE HEALTH OF VETERANS OF ALL GENERATIONS THROUGH RESEARCH AND EDUCATION. 13 12 146 1 0 0 11496017 11922392 4416553 4672519 0 0 0 0 15912570 16594911 0 0 0 0 11102471 11870259 0 0 0 5321863 5529025 16424334 17399284 -511764 -804373 6229193 6698249 4580806 5854235 1648387 844014 X HONORING MILITARY SERVICE WITH SCIENCE; OUR BENCH-TO-BEDSIDE APPROACH HAS LED TO BREAKTHROUGHS IN AREAS SUCH AS SHINGLES PREVENTION, HEART DISEASE, METABOLIC DISEASES AND GROUND BREAKING WORK ON POST-TRAUMATIC STRESS DISORDER. 0 0 8640427 2549273 DR. IX - KIDNEY TUBULAR DAMAGE AND DYSFUNCTION IDENTIFY A NOVEL AXIS OF CHRONIC KIDNEY: PATHOLOGIC STUDIES DEMONSTRATE THAT KIDNEY TUBULE INJURY, ATROPHY, AND FIBROSIS ARE COMMON FEATURES OF CHRONIC KIDNEY DISEASE (CKD) AND ARE HIGHLY PREDICTIVE OF PROGRESSION TO DIALYSIS. ESTABLISHED CKD RISK FACTORS INCLUDING HYPERTENSION AND ADVANCED AGE ARE ASSOCIATED WITH TUBULAR INJURY AND FIBROSIS ON BIOPSY. HOWEVER, CURRENT CLINICAL ASSESSMENT OF CKD EVALUATES ONLY GLOMERULAR FUNCTION (GFR) AND GLOMERULAR INJURY (ALBUMINURIA), BUT NOT KIDNEY TUBULAR DYSFUNCTION OR INJURY. THE OVERALL HYPOTHESIS OF THIS APPLICATION IS THAT KIDNEY TUBULAR DYSFUNCTION AND INJURY ARE MEASURABLE CONTRIBUTORS TO CKD PATHOGENESIS AND PROGNOSIS.DYSFUNCTION OF THE KIDNEY TUBULES WILL BE ASSESSED BY THREE INDICES: (1) RENAL TUBULE RESISTANCE TO HORMONE ACTIONS OF FGF23 AND PTH; (2) ACID/BASE HOMEOSTASIS; AND (3) URINE RE-ABSORPTIVE CAPACITY.WE WILL: (1) DETERMINE THE ASSOCIATION OF KIDNEY TUBULAR DYSFUNCTION AND INJURY WITH RISK OF CVD EVENTS, (2) DETERMINE THE ASSOCIATION OF KIDNEY TUBULAR DYSFUNCTION AND INJURY WITH CKD PROGRESSION, AND (3) DETERMINE WHETHER RANDOMIZATION TO INTENSIVE BLOOD PRESSURE MANAGEMENT ARM OF THE TRIAL SLOWS PROGRESSION OF KIDNEY TUBULAR DYSFUNCTION AND INJURY OVER TIME COMPARED WITH STANDARD BLOOD PRESSURE MANAGEMENT. 839375 950861 DR. GUATELLI-ENHANCEMENT OF INFECTIVITY BY HIV-1 VIA ANTAGONISM OF SERINC PROTEINS.THE PURPOSE OF THIS PROJECT IS TO 1) COMBINE OUR BIOCHEMICAL, CELL BIOLOGIC, AND VIROLOGIC ASSAYS TO VALIDATE AND ELABORATE THESE MECHANISMS 2) DETERMINE THE STRUCTURAL BASIS OF SERINC ANTAGONISM BY NEF. WE AIM TO PROVIDE HIGH-RESOLUTION STRUCTURES OF THE INTERACTION OF NEF WITH SERING PROTEINS AND CLATHRIN ADAPTORS. 3) DETERMINE HOW SERING PROTEINS AFFECT INFECTIVITY IN AN ENV-DEPENDENT MANNER. TO FACILITATE AN UNDERSTANDING OF SERINC FUNCTION, WE WILL CHARACTERIZE A FULL-LENGTH PROTEIN BIOPHYSICALLY AND AIM TO PROVIDE A HIGH-RESOLUTION STRUCTURE. WE WILL TEST THE HYPOTHESIS THAT SERINC PROTEINS INTERACT WITH ENV TO INHIBIT INFECTIVITY AND MAP THE INTERACTION. WE WILL DETERMINE WHETHER SERINC PROTEINS AFFECT THE CONFORMATION OF ENV TRIMERS AS DISPLAYED ON THE CELL SURFACE AND ON VIRIONS. LASTLY, WE WILL ELABORATE A MODEL IN WHICH THE CYTOPLASMIC DOMAIN OF ENV CONTRIBUTES TO COUNTERACTION OF SERING PROTEINS. WHEN THE PROPOSED EXPERIMENTS ARE COMPLETE, WE SHOULD HAVE A HIGH RESOLUTION MECHANISTIC UNDERSTANDING OF HOW NEF COUNTERACTS THE INHIBITORY INFLUENCE OF THE SERINC PROTEINS ON VIRAL INFECTIVITY, AND A MODEL FOR HOW THE ACTIVITY OF ENV IS INHIBITED BY THESE PROTEINS 696603 625779 DR. LANG MULTI-SITE FEASIBILITY OF COMPASSION MEDITATION FOR VETERANS WITH PTSD HE OVERALL GOAL OF THIS APPLICATION IS TO LEVERAGE AN EXISTING COMPASSION MEDITATION (CM) PROTOCOL TO DEVELOP THE COGNITIVELY BASED COMPASSION TRAINING (CBCT-VET) FOR VETERANS WITH PTSD. SPECIFICALLY, THIS PROJECT AIMS TO EXAMINE THE FEASIBILITY OF A MULTI-SITE TRIAL OF CBCT-VET COMPARED TO A RELAXATION CONTROL (VETERAN.CALM); DEVELOP PROCEDURES FOR THERAPIST TRAINING AND FIDELITY MONITORING; AND, PILOT TEST MULTI-MODAL ASSESSMENT PROCEDURES. IF SUCCESSFUL, THIS PROJECT COULD INFORM THE STUDY DESIGN OF A FUTURE LARGER-SCALE RCT MULTI- SITE EFFICACY STUDY AND CONTRIBUTE TO THE KNOWLEDGE BASE OF NON-PHARMACOLOGICAL BEHAVIORAL APPROACHES FOR PTSD IN UNDERTREATED VETERANS, A SIGNIFICANT PUBLIC HEALTH CONCERN. 2478200 546606 VETERANS MEDICAL RESEARCH FOUNDATION OF SAN DIEGO, WHERE WE HONOR SERVICE WITH SCIENCE, IS THE REGION'S ONLY MEDICAL RESEARCH INSTITUTE DEDICATED TO VETERANS. WE FACILITATE WORLD-CLASS RESEARCH AT THE VA SAN DIEGO HEALTHCARE SYSTEM THAT PROVIDES IMPROVEMENTS FOR VETERANS' HEALTHCARE. WHILE FOCUSED ON VETERANS, OUR MEDICAL ADVANCES EXTEND TO THE ENTIRE POPULATION AND RAISE THE STANDARD OF CARE FOR EVERYONE. 2478200 546606 12654605 1 1 0 1 0 0 0 0 0 0 1 0 0 0 0 1 1 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 22 0 146 1 0 0 0 0 0 0 0 0 0 0 0 0 X 13 12 0 0 0 0 0 1 1 1 1 0 0 1 1 1 1 1 1 1 1 0 CA X ADAM CASSIUS CFO 8583544792 3350 LA JOLLA VILLAGE DRIVE BLDG 13 SAN DIEGO CA 92161 PHILLIP L JELSMA ESQ CHAIRMAN 4.00 X 0 0 0 PETE HEKMAN VADM USN RET VICE CHAIRMAN 1.00 X 0 0 0 ERICA LIN MD DIRECTOR 1.00 X 0 0 0 DOLLARHIDE ADRIAN MD DIRECTOR 1.00 X 0 0 0 WILLIAM CARON DIRECTOR 1.00 X 0 0 0 PAUL PEARIGEN MD RDML USN RET DIRECTOR 1.00 X 0 0 0 ROBIN SAMIT ESQ DIRECTOR 1.00 X 0 0 0 ROBERT B HALDER MD RADM USN RET DIRECTOR 1.00 X 0 0 0 BARBARA NOERENBERG DIRECTOR 1.00 X 0 0 0 GERHARD SCHULTEIS PHD DIRECTOR 1.00 X 0 0 0 FRANK PEARSON DPT PA-C DIRECTOR 1.00 X 0 0 0 LARY EDDINGFIELD CAPT USN RET DIRECTOR 1.00 X 0 0 0 MARK BIPES RDML USN RET DIRECTOR 1.00 X 0 0 0 MICHAEL KIEFER DIRECTOR 1.00 X 0 0 0 SITTMANN MARIA EXECUTIVE DIRECTOR/CEO 40.00 X 326520 0 24372 CASSIUS ADAM CFO 40.00 X 195456 0 21104 HARBECKE RUTH M RESEARCH ASSOCIATE 40.00 X 145785 0 21163 DOHNER MATTHEW POST AWARD DIRECTOR 40.00 X 127188 0 19729 FREISER JEAN PRE AWARD DIRECTOR 40.00 X 119580 0 11602 BRAY MARI V VMU DIRECTOR 40.00 X 112094 0 10977 FUNK STEPHEN RESEARCH ASSOCIATE 40.00 X 112091 0 8931 1138714 0 117878 8 0 1 0 UNIVERSITY OF SOUTHERN CALIFORNIA 3551 TROUSDALE PKWY LOS ANGELES CA 90007 LAB SERVICES 210421 REGENTS OF THE UNIVERSITY OF CALIFORNIA 9500 GILMAN DRIVE LA JOLLA CA 92093 LAB SERVICES 204576 UNIVERSITY OF WASHINGTON 1410 NE CAMPUS PKWY SEATTLE WA 98195 LAB SERVICES 100785 3 11083640 838752 11922392 CLINICAL RESEARCH REVENUE 541700 1324559 1324559 UPA/IPA 541700 1224714 1224714 GRANT REVENUE 541700 950861 950861 OTHER INCOME 541700 625779 625779 RECHARGE INCOME 541700 546606 546606 4672519 16594911 4672519 0 0 X 657247 657247 10006669 7909701 2096968 268766 131106 137660 508191 290566 217625 429386 241556 187830 59993 57607 2386 1785 960 825 98125 98125 1475 1475 3515668 2744920 770748 80 80 59651 34580 25071 12593 12593 45782 39853 5929 36148 36148 35363 13687 21676 1828 1502 326 56264 14605 41659 254316 254316 SUPPLIES 810372 670012 140360 EQUIPMENT 355741 305792 49949 SALES TAX 68450 64302 4148 POSTAGE AND FREIGHT 39903 38398 1505 75488 59230 16258 17399284 12654605 4744679 0 727290 2427423 1177473 374623 3591508 3175798 4509 4509 244493 168008 7970924 7424944 437997 545980 45923 1908 6229193 6698249 3302233 2863214 1278573 2991021 4580806 5854235 X 1561929 747391 86458 96623 1648387 844014 6229193 6698249 -804373 0 X 0 1 X 1 1 1 X 11796712 11158657 11263636 11496017 11922392 57637414 11796712 11158657 11263636 11496017 11922392 57637414 57637414 19851 900 7 0 0 20758 57658172 21896506 0.99960 0.99930 X RESTRICTED RESTRICTED RESTRICTED RESTRICTED RESTRICTED RESTRICTED RESTRICTED RESTRICTED 0 0 0 0 0 0 0 0 1 1475 1475 0 PART II-B, LINE 1: VMRF IS A MEMBER OF NAVREF (NATIONAL ASSOCIATION OF VETERAN RESEARCH & EDUCATION FOUNDATIONS), AIRI (ASSOCIATION OF INDEPENDENT RESEARCH INSTITUTES) AND CALIFORNIA CHAMBER OF COMMERCE AND A SMALL PORTION OF THE MEMBERSHIP AMOUNT IS ATTRIBUTED TO LOBBYING. 5846149 5512072 334077 2124775 1912872 211903 545980 X 16594911 0 16594911 0 16594911 17399284 0 17399284 0 17399284 PART X, LINE 2: THE ORGANIZATION RECOGNIZES ACCRUED INTEREST AND PENALTIES ASSOCIATED WITH UNCERTAIN TAX POSITIONS AS PART OF THE INCOME TAX PROVISION, WHEN APPLICABLE. THERE ARE NO AMOUNTS ACCRUED IN THE FINANCIAL STATEMENTS RELATED TO UNCERTAIN TAX POSITIONS FOR THE YEARS ENDED SEPTEMBER 30, 2024 AND 2023. X X X X X 0 0 0 0 0 0 0 0 0 SITTMANN MARIA EXECUTIVE DIRECTOR/CEO 321520 0 5000 0 0 0 24222 0 150 0 350892 0 0 0 CASSIUS ADAM CFO 190456 0 5000 0 0 0 15940 0 5164 0 216560 0 0 0 HARBECKE RUTH M RESEARCH ASSOCIATE 145785 0 0 0 0 0 12382 0 8781 0 166948 0 0 0 PART I, LINE 3 SALARIES OF EXECUTIVE OFFICERS WERE REVIEWED AND RECOMMENDED FOR BOARD APPROVAL BY THE COMPENSATION COMMITTEE. SALARY REVIEWS INCORPORATE PERFORMANCE REVIEW RESULTS AND JOB SPECIFIC COMPARISON SALARY DATE FROM LIKE ORGANIZATIONS, AS WELL AS TWO NATIONAL SALARY SURVEYS. THE TO-BE-EVALUATED PERSON DOES NOT PARTICIPATE IN THE SALARY DISCUSSION OR DECISION MAKING PROCESS AND IS EXCUSED FROM THAT PART OF THE MEETING(S). THE BOARD CHAIRMAN IS THE ONLY PAID BOARD MEMBER AND THE CHAIRMAN'S HONORARIUM WAS BOARD APPROVED. FORM 990, PART VI, SECTION A, LINE 7A THE VETERANS MEDICAL RESEARCH FOUNDATION BOARD OF DIRECTORS INCLUDES FOUR (4) MANDATORY BOARD MEMBERS REPRESENTING THE VA SAN DIEGO HEALTHCARE SYSTEM (VASDHS) AND ONE BOARD MEMBER REPRESENTING VA SOUTHERN NEVADA HEALTHCARE SYSTEM (VASNHS). THESE MEMBERS ARE THE VASDHS DIRECTOR, CHIEF OF STAFF, ASSOCIATE CHIEF OF STAFF FOR RESEARCH AND DEVELOPMENT, THE ASSOCIATE CHIEF OF STAFF FOR EDUCATION, AND THE VASNHS DIRECTOR. ALL OF THESE VAS LEADERS ARE ULTIMATELY HIRED AND APPROVED BY THE DEPARTMENT OF VETERANS AFFAIRS VETERANS HEALTH ADMINISTRATION. FORM 990, PART VI, SECTION A, LINE 7B THE VETERANS MEDICAL RESEARCH FOUNDATION'S BOARD MEMBERS MUST BE SPECIFICALLY APPROVED BY THE DIRECTOR OF VASDHS. THE DIRECTOR OF THE VASDHS IS A VOTING MEMBER OF THE VMRF BOARD OF DIRECTORS AND HAS THE SAME VOTING RIGHTS AS ALL OTHER VOTING MEMBERS. FORM 990, PART VI, SECTION B, LINE 11B AFTER INTERNAL REVIEW BY THE EXECUTIVE DIRECTOR, CFO, AND THE ACCOUNTING DIRECTOR, THE AUDITORS REVIEW THE 990 WITH THE AUDIT COMMITTEE. THE 990 IS THEN DISTRIBUTED TO THE BOARD PRIOR TO FINAL APPROVAL BY THE EXECUTIVE DIRECTOR AND CEO. FORM 990, PART VI, SECTION B, LINE 12C MEMBERS OF THE BOARD OF DIRECTORS AND EXECUTIVE OFFICERS ARE REQUIRED TO COMPLETE AND SIGN A COI DISCLOSURE QUESTIONNAIRE (INCLUDING DISCLOSURE PERTAINING TO SPOUSE OR DEPENDENT CHILDREN) AND TO SIGN A VMRF COI AFFIRMATION OF COMPLIANCE STATEMENT. VMRF'S POLICY ON COI INCLUDES DISCLOSURE REQUIREMENTS, PROCEDURES FOR REVIEW OF POTENTIAL CONFLICTS AND ADDRESSING CONFLICTS OF INTERESTS, AS WELL AS PROVISIONS ON WHAT DISCIPLINARY ACTIONS TO TAKE IN CASE OF VIOLATIONS OF THE BOARD APPROVED COI POLICY. INTERESTED PARTIES WITH A POTENTIAL COI RE: PROPOSED ACTION, POLICY, OR TRANSACTION OF VMRF SHALL NOT PARTICIPATE IN ANY WAY OR BE PRESENT DURING THE DELIBERATION AND DECISION-MAKING FOR SUCH ACTION. ALL ANNUAL BOARD AND KEY EMPLOYEE DISCLOSURE FORMS ARE REVIEWED BY THE EXECUTIVE DIRECTOR. IF THERE ARE CONFLICTS, THEY WILL BE MANAGED AS PER POLICY. THE EXECUTIVE DIRECTOR'S DISCLOSURE IS REVIEWED BY THE BOARD CHAIRMAN AND IF RESEARCH RELATED, BY THE INSTITUTIONAL INDEPENDENT REVIEW BOARD. FORM 990, PART VI, SECTION B, LINE 15 SALARIES OF EXECUTIVE OFFICERS WERE REVIEWED AND RECOMMENDED FOR BOARD APPROVAL BY THE COMPENSATION COMMITTEE. SALARY REVIEWS INCORPORATE PERFORMANCE REVIEW RESULTS AND JOB SPECIFIC COMPARISON SALARY DATA FROM LIKE ORGANIZATIONS, AS WELL AS TWO NATIONAL SALARY SURVEYS. THE TO-BE-EVALUATED PERSON DOES NOT PARTICIPATE IN THE SALARY DISCUSSION OR DECISION MAKING PROCESS AND IS EXCUSED FROM THAT PART OF THE MEETING(S). THE BOARD CHAIRMAN IS THE ONLY PAID BOARD MEMBER AND THE CHAIRMAN'S HONORARIUM WAS BOARD APPROVED. FORM 990, PART VI, SECTION C, LINE 18 IT IS NOTED ON THE WEBSITE THAT THESE DOCUMENTS ARE AVAILABLE UPON REQUEST BY CONTACTING THE VMRF CFO. FORM 990, PART VI, SECTION C, LINE 19 THE ORGANIZATION MAKES THE A133 AUDITED FINANCIALS AVAILABLE ONLY IF REQUIRED BY A GRANTOR. FORM 990, PART IX, LINE 11G ADMINISTRATION FEES: PROGRAM SERVICE EXPENSES 0. MANAGEMENT AND GENERAL EXPENSES 477,858. FUNDRAISING EXPENSES 0. TOTAL EXPENSES 477,858. PROFESSIONAL SERVICES: PROGRAM SERVICE EXPENSES 509,784. MANAGEMENT AND GENERAL EXPENSES 271,753. FUNDRAISING EXPENSES 0. TOTAL EXPENSES 781,537. PATIENT SERVICES: PROGRAM SERVICE EXPENSES 26,649. MANAGEMENT AND GENERAL EXPENSES 0. FUNDRAISING EXPENSES 0. TOTAL EXPENSES 26,649. SUBCONTRACTOR EXPENSES: PROGRAM SERVICE EXPENSES 2,208,427. MANAGEMENT AND GENERAL EXPENSES 0. FUNDRAISING EXPENSES 0. TOTAL EXPENSES 2,208,427. BANK FEES: PROGRAM SERVICE EXPENSES 60. MANAGEMENT AND GENERAL EXPENSES 21,137. FUNDRAISING EXPENSES 0. TOTAL EXPENSES 21,197.