2026-07-15T09:37:09-05:00 2025-09-30 861065772 DELOITTE TAX LLP 111 MONUMENT CIRCLE SUITE 4200 INDIANAPOLIS IN 462045108 990 2024-10-01 330435954 THE SCRIPPS RESEARCH INSTITUTE SCRI 8587841000 10550 NORTH TORREY PINES ROAD LA JOLLA CA 92037 JARED MACHADO CHIEF FINANCIAL OFFICER 8587849817 2026-07-10 1 1 SHAWNA M JANSONS P01222873 3174648600 2024 2025-03-06 01:10:19Z PETER SCHULTZ PHD 10550 NORTH TORREY PINES ROAD LA JOLLA CA 92037 1358708093 0 X WWW.SCRIPPS.EDU X 1924 CA TSRI CONDUCTS BIOMEDICAL AND BIOCHEMICAL RESEARCH AND POSTGRADUATE TRAINING PROGRAMS. 16 14 2022 14 -123639 0 370268955 317961835 2212057 1811390 30267045 36569701 238358106 342281392 641106163 698624318 127840846 117089363 0 0 203451715 202849110 389103 0 7540995 196756129 217515508 528437793 537453981 112668370 161170337 1299917796 1460616898 368128581 306765344 931789215 1153851554 X THE SCRIPPS RESEARCH INSTITUTE ("TSRI") PERFORMS HIGH IMPACT BASIC BIOMEDICAL RESEARCH, IMPROVES THE HUMAN CONDITION BY FOSTERING TRANSLATION OF ITS DISCOVERIES INTO USEFUL PRODUCTS AND ENGAGES IN THE HIGHEST QUALITY GRADUATE SCIENTIFIC EDUCATION AND POST GRADUATE SCIENTIFIC TRAINING. TSRI IS KNOWN FOR ITS ENTREPRENEURIAL ENVIRONMENT AND ITS EMPHASIS IN RESEARCH RELATING TO SYNTHETIC CHEMISTRY, THE RELATIONSHIP BETWEEN MOLECULAR STRUCTURE AND ACTIVITY AND CHEMICAL BIOLOGY. 0 0 473621099 99620335 9803187 GROUNDBREAKING SCIENTIFIC RESEARCH IS CONDUCTED AT TSRI CAMPUSES IN LA JOLLA, CALIFORNIA, SUPPORTED BY GRANTS, CONTRACTS AND FELLOWSHIPS FROM PUBLIC AND PRIVATE INSTITUTES AND INDIVIDUALS. TSRI'S UNIQUE STRUCTURE MERGES BASIC SCIENTIFIC STUDIES IN BIOLOGY, CHEMISTRY AND BIOINFORMATICS WITH TRANSLATIONAL SCIENCE TO PRODUCE THE NEXT GENERATION OF DRUGS AND ADVANCES IN DIGITAL AND PRECISION MEDICINE. SCIENTIFIC DISCOVERIES AT TSRI SEED JOINT DRUG DISCOVERY PROJECTS AT CALIBR-SKAGGS, A DIVISION OF TSRI, CREATING A PIPELINE OF DRUG CANDIDATES THAT WILL IMPACT PATIENTS FOR YEARS TO COME. THE SCRIPPS RESEARCH TRANSLATIONAL INSTITUTE, ANOTHER DIVISION OF TSRI, AIMS TO INDIVIDUALIZE HEALTHCARE BY LEVERAGING THE PROGRESS BEING MADE IN HUMAN GENOMICS AND COMBINING IT WITH THE POWER OF WIRELESS DIGITAL TECHNOLOGIES AND ARTIFICIAL INTELLIGENCE. 20835219 17469028 TSRI IS COMMITTED TO EDUCATING, TRAINING AND INSPIRING THE SCIENTISTS OF TOMORROW. THE INSTITUTE'S SKAGGS GRADUATE SCHOOL OF CHEMICAL AND BIOLOGICAL SCIENCES, RANKED ONE OF THE TEN BEST GRADUATE PROGRAMS IN THE COUNTRY, EMPOWERS STUDENTS TO MAKE HIGH-IMPACT DISCOVERIES AT THE INTERFACE OF CHEMISTRY AND BIOLOGY. STUDENTS IN THE SKAGGS GRADUATE SCHOOL ARE IMMERSED IN INTENSIVE LABORATORY RESEARCH FROM DAY ONE AND PURSUE AMBITIOUS INVESTIGATIONS ACROSS SCIENTIFIC DISCIPLINES. GRADUATES OF THE SCHOOL BECOME EDUCATORS AT TOP UNIVERSITIES AND RESEARCH INSTITUTES, THOUGHT LEADERS WITHIN GOVERNMENT DEPARTMENTS AND INNOVATORS AT PHARMACEUTICAL AND BIOTECHNOLOGY COMPANIES. POSTDOCTORAL ASSOCIATES ARRIVE AT TSRI FROM ALL OVER THE GLOBE, SEEKING TO EXPAND THEIR KNOWLEDGE AND TRAINING BY WORKING ALONGSIDE OUR WORLD-RENOWNED SCIENTISTS. THE SCRIPPS FELLOWS PROGRAM IDENTIFIES INDIVIDUALS WITH AN OUTSTANDING RECORD OF GRADUATE RESEARCH AND MOVES THEM INTO THEIR OWN LABORATORIES, ALLOWING THEM TO LEAPFROG THEIR POSTDOCTORAL YEARS OF STUDY AND BEGIN PUSHING THE FRONTIERS OF SCIENTIFIC DISCOVERY. 494456318 1 1 0 0 0 0 0 0 0 1 1 1 0 0 1 0 0 1 0 0 1 1 0 0 0 0 0 1 1 1 1 0 0 0 0 0 0 0 0 0 0 1 0 0 0 1 1 1 1 0 0 1 517 0 1 2022 1 1 1 0 0 0 0 0 0 0 0 0 1 0 X 16 14 0 0 0 0 0 0 0 1 1 0 0 1 1 1 1 1 1 1 1 0 AK AR CA CO DC FL HI KS KY MA MD ME MI MS ND NH NJ NV NY OH OK OR RI SC WA X JARED MACHADO 8587841000 10550 N TORREY PINES DRIVE LA JOLLA CA 92037 PETER G SCHULTZ PRESIDENT/CEO 40.00 0.00 X X 1784580 0 74660 BENJAMIN CRAVATT FACULTY DIRECTOR (START 10/24)/PROF 40.00 0.00 X 390594 0 39791 ARDEM PATAPOUTIAN FACULTY DIRECTOR (END 10/24)/PROF 9.20 0.00 X 142661 0 0 JOHN D DIEKMAN DIRECTOR/BOARD CHAIR 1.00 0.00 X 0 0 0 BARBARA KOSACZ DIRECTOR 1.00 0.00 X 0 0 0 BENEDICT GROSS DIRECTOR (END 10/24) 1.00 0.00 X 0 0 0 CLAUDIA S LUTTRELL DIRECTOR 1.00 0.00 X 0 0 0 GENE LAY DIRECTOR 1.00 0.00 X 0 0 0 GERALD CHAN DIRECTOR 1.00 0.00 X 0 0 0 HERBERT WERTHEIM DIRECTOR 1.00 0.00 X 0 0 0 LILLIAN LOU DIRECTOR 1.00 0.00 X 0 0 0 LOU LANGE DIRECTOR (START 10/24) 1.00 0.00 X 0 0 0 MARK EDWARDS DIRECTOR 1.00 0.00 X 0 0 0 MARK PEARSON DIRECTOR 1.00 0.00 X 0 0 0 PETER C FARRELL DIRECTOR 1.00 0.00 X 0 0 0 RON BURKLE DIRECTOR 1.00 0.00 X 0 0 0 SHERRY LANSING DIRECTOR 1.00 0.00 X 0 0 0 TOM DANIEL DIRECTOR 1.00 0.00 X 0 0 0 CAROLINE MOON CFO 40.00 0.00 X 832577 0 65791 MARSHALL OLIN GENERAL COUNSEL 40.00 0.00 X 672211 0 74166 JARED M MACHADO TREASURER/CHIEF ACCOUNTING OFFICER 40.00 0.00 X 371821 0 52864 ALANNA RUTAN SECRETARY/CHIEF COMPLIANCE COUNSEL 40.00 0.00 X 272207 0 45635 KELLY SAN GEORGE CFO VP ADM. 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SCHEDULE F, PART IV: TSRI HAS LESS THAN 10% OWNERSHIP IN A FOREIGN CORPORATION DURING THE TAX YEAR, AND THEREFORE, WAS NOT REQUIRED TO FILE FORM 5471. 1 1NHEALTH INC 424 E CENTRAL BLVD ORLANDO FL 32801 832789875 204423 0 GRANTS FOR SCIENTIFIC RESEARCH ABZENA (SAN DIEGO) INC 8810 REHCO RD SAN DIEGO CA 92121 731731905 125176 0 GRANTS FOR SCIENTIFIC RESEARCH AIT WORLDWIDE LOGISTICS INC 1820 W 19TH ST TORRANCE CA 90501 363033973 501(C)(3) 19575 0 GRANTS FOR SCIENTIFIC RESEARCH ALBERT EINSTEIN COLLEGE OF MEDICINE 1300 MORRIS PARK AVE BRONX NY 10461 830621846 501(C)(3) 135720 0 GRANTS FOR SCIENTIFIC RESEARCH APPLIED BIOMEDICAL SCIENCE INSTITUTE 11011 VIA FRONTERA STE D SAN DIEGO CA 92127 825056708 501(C)(3) 445162 0 GRANTS FOR SCIENTIFIC RESEARCH AUGUSTA UNIVERSITY RESEARCH INSTITUTE INC PO BOX 945552 ATLANTA GA 30394 581418202 501(C)(3) 728286 0 GRANTS FOR SCIENTIFIC RESEARCH AVANCE BIOSCIENCES INC 9770 WEST LITTLE YORK RD HOUSTON TX 77040 275231828 91883 0 GRANTS FOR SCIENTIFIC RESEARCH 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DOMESTIC ORGANIZATION BY ADHERENCE TO A GRANT CONTRACT AND MONITORS DETAILED BILLING STATEMENTS OF RESEARCH EXPENDITURES. GRADUATE STUDENT STIPENDS ARE PROCESSED VIA PERSONNEL ACTION FORMS WHICH ARE APPROVED BY THE GRADUATE OFFICE AND HUMAN RESOURCES PRIOR TO BEING SENT TO THE PAYROLL OFFICE. ONCE APPROVED, GRADUATE STUDENTS ARE SET UP IN TSRI'S PAYROLL SYSTEM AND ARE DISPERSED ON THE 1ST AND 15TH OF EACH MONTH. MONITORING IS DONE VIA THE INTERACTION BETWEEN THE STUDENT AND FACULTY ADVISOR. AS LONG AS THE STUDENT IS PROGRESSING, SHE/HE WOULD CONTINUE TO BE PAID. 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TRAVEL FOR COMPANIONS, WHICH IS TREATED AS TAXABLE COMPENSATION, WAS PROVIDED TO ONE OFFICER. TAX GROSS-UPS ARE PROVIDED FOR HOUSING REIMBURSEMENTS AND TRAVEL FOR COMPANIONS. ONE OFFICER RECEIVED THIS BENEFIT, WHICH WAS TREATED AS TAXABLE COMPENSATION TO THE INDIVIDUAL. TAX GROSS-UPS ARE ALSO PROVIDED FOR RELOCATION. ONE HIGHEST COMPENSATED EMPLOYEE RECEIVED THIS BENEFIT, WHICH WAS TREATED AS TAXABLE COMPENSATION TO THE INDIVIDUAL. FORM 990, PART VII, SECTION A, LINE 5 AND SCHEDULE J: ERIC TOPOL, M.D., RECEIVED COMPENSATION FROM AN UNRELATED ORGANIZATION, SCRIPPS CLINIC MEDICAL GROUP, FOR SERVICES PROVIDED TO THE SCRIPPS RESEARCH INSTITUTE. IN 2024, IN EXCHANGE FOR THESE SERVICES, THE SCRIPPS RESEARCH INSTITUTE REIMBURSED THE SCRIPPS MEDICAL GROUP $750,000. A CALIFORNIA INFRASTRUCTURE & ECONOMIC DEVELOPMENT BANK 630304653 13034AMU1 2016-08-29 40511601 SEE PART VI 0 0 0 A 21390000 40511601 648703 39862898 2016 1 1 1 1 A 0 0 0 1 0 0.00000 0.00000 0.00000 0 0 1 A 0 0 0 1 0 0 0 0 1 A 1 DATE REBATE COMPUTATION PERFORMED ISSUER NAME: CALIFORNIA INFRASTRUCTURE & ECONOMIC DEVELOPMENT BANK DATE THE REBATE COMPUTATION WAS PERFORMED: 06/29/2022 SCHEDULE K, PART I, BOND ISSUES: (A) ISSUE NAME: CALIFORNIA INFRASTRUCTURE & ECONOMIC DEVELOPMENT BANK (F) DESCRIPTION ON PURPOSE: REFUND AND DEFEASE BONDS PREVIOUSLY ISSUED FOR THE BENEFIT OF THE INSTITUTE ON 06/29/2000 AND 02/23/2005. SCHEDULE K, PART III, LINE 3D: OVERALL PRIVATE USE ISN'T MATERIAL, AND OUTSIDE COUNSEL WOULD REVIEW ANY SIGNIFICANT AGREEMENTS. SCHEDULE K, PART IV, LINE 6: THIS QUESTION IS BEING ANSWERED WITHOUT REGARD TO A YIELD-RESTRICTED ADVANCE REFUNDING ESCROW FINANCED WITH PROCEEDS OF THE BONDS. X 7 1406589 COST OR SELLING PRICE 0 0 1 0 PART I, COLUMN (B): NUMBER OF CONTRIBUTIONS OF PUBLICLY TRADED STOCK CONTRIBUTIONS FORM 990, PART VI, SECTION B, LINE 11B ON JUNE 2, 2026, THE AUDIT COMMITTEE REVIEWED A DRAFT OF THE FORM 990 (INCLUDING ALL SUPPLEMENTAL SCHEDULES). THIS REVIEW INCLUDED A PRESENTATION OF THE STATEMENTS BY THE STAFF WITH PARTICULAR EMPHASIS ON DISCLOSURES ABOUT GOVERNANCE. THE PRESENTATIONS TO THE AUDIT COMMITTEE DO NOT CONTAIN INFORMATION ABOUT TRANSACTIONS WITH INTERESTED PERSONS. TRANSACTIONS WITH INTERESTED PERSONS ARE PRESENTED TO THE FULL BOARD. THE 990 WILL BE PROVIDED TO THE FULL BOARD OF DIRECTORS PRIOR TO FILING. FORM 990, PART VI, SECTION B, LINE 12C TSRI'S CONFLICT OF INTEREST POLICIES AND PROCEDURES APPLY TO MEMBERS OF THE BOARD OF DIRECTORS, OFFICERS, KEY PERSONNEL, AND EMPLOYEES (ALTOGETHER COVERED INDIVIDUALS), REQUIRING DISCLOSURE OF CERTAIN FINANCIAL INTERESTS OF THE COVERED INVIDUAL AND THEIR FAMILY MEMBERS IN ORDER TO PROTECT THE INTERESTS OF TSRI WHEN IT IS CONTEMPLATING ENTERING INTO A TRANSACTION OR ARRANGEMENT THAT COULD: 1) BENEFIT THE PRIVATE INTEREST OF A COVERED INDIVIDUAL WITHIN THE MEANING OF TREASURY REGULATION SECTION 1.501(C)(3)-1(D)(1)(II), 2) RESULT IN A POSSIBLE EXCESS BENEFIT TRANSACTION WITHIN THE MEANING OF SECTION 4958(C) OF THE INTERNAL REVENUE CODE OF 1986, AS AMENDED; OR 3) BE A SELF-DEALING TRANSACTION WITHIN THE MEANING OF SECTION 5233 OF THE CALIFORNIA CORPORATIONS CODE (THE "CORPORATIONS CODE"). TSRI'S POLICIES AND PROCEDURES ARE INTENDED TO SUPPLEMENT, BUT NOT REPLACE, ANY STATE AND FEDERAL LAWS GOVERNING ACTUAL, POTENTIAL, OR APPARENT CONFLICT OF INTEREST APPLICABLE TO TSRI. DISCLOSURE DOCUMENTS RESPONSIVE TO TSRI'S POLICIES ARE ANNUALLY SUBMITTED BY COVERED INDIVIDUALS, AND ARE REVIEWED BY TSRI ADMINISTRATION FOR PERTINENT RELATIONSHIPS. ANY TRANSACTIONS OR ARRANGEMENTS INVOLVING COVERED INDIVIDUALS THAT FALL WITHIN THE SCOPE OF APPLICABLE STATE AND FEDERAL LAWS GOVERNING ACTUAL, POTENTIAL, OR APPARENT CONFLICT OF INTEREST ARE THEN SUBJECT TO REVIEW AND CONSIDERATION BY NON-CONFLICTED BOARD OF DIRECTOR MEMBERS, WITH CONFLICTED MEMBERS BEING RECUSED FROM ANY DEBATE AND VOTE TO APPROVE OR DISAPPROVE. FORM 990, PART VI, SECTION B, LINE 15 THE COMPENSATION OF THE CEO AND CERTAIN OTHER KEY EXECUTIVES WAS REVIEWED AND APPROVED BY THE BOARD OF DIRECTORS. THIS REVIEW WAS BASED, IN PART, ON ANALYSIS PERFORMED BY THE HUMAN RESOURCES DEPARTMENT, AND INCLUDED DATA FROM OUTSIDE CONSULTANTS OR INTERNALLY-CONDUCTED RESEARCH. ON AN ONGOING BASIS, EXECUTIVES MAY PARTICIPATE IN THE NORMAL ANNUAL SALARY INCREASE PROGRAM, WHICH IS BASED ON A RECOMMENDATION FROM THE HUMAN RESOURCES DEPARTMENT BASED ON MARKET RESEARCH. ANY UNUSUAL OR POTENTIALLY NON-QUALIFIED COMPENSATION WOULD BE REVIEWED BY OUTSIDE COUNSEL FOR ANY TAX COMPLIANCE ISSUES. FORM 990, PART VI, SECTION C, LINE 19 GOVERNING DOCUMENTS AND CONFLICT OF INTEREST POLICIES ARE NOT AVAILABLE TO THE PUBLIC AT THIS TIME. THE FINANCIAL STATEMENTS ARE PROVIDED TO BOND HOLDERS THROUGH TSRI'S DISSEMINATION AGENT. THE ANNUAL INFORMATION RETURN IS PROVIDED UPON REQUEST. FORM 990, PART IX, LINE 11G PURCHASED SERVICES & MAINTENANCE: PROGRAM SERVICE EXPENSES 71,517,926. MANAGEMENT AND GENERAL EXPENSES 0. FUNDRAISING EXPENSES 8,940. TOTAL EXPENSES 71,526,866. 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