2024-10-18T13:45:02-05:00 2023-09-30 911194016 CLARK NUBER PS 10900 NE 4TH STREET SUITE 1400 BELLEVUE WA 98004 990 2022-10-01 910667886 PACIFIC NORTHWEST RESEARCH INSTITUTE PACI 2067261200 720 BROADWAY SEATTLE WA 98122 DIONNE GORDON CFAO 2067261200 2024-10-16 1 0 MEGAN R RYAN P00737884 4254544919 2024-10-16 2022 2024-10-15 13:58:12Z DIONNE GORDON 720 BROADWAY SEATTLE WA 98122 5662529 0 X WWW.PNRI.ORG X 1956 WA AN INDEPENDENT, BIOMEDICAL RESEARCH INSTITUTE AIMED AT UNDERSTANDING HOW HEALTH IS MAINTAINED IN THE FACE OF GENETIC AND ENVIRONMENTAL RISKS ASSOCIATED WITH DISEASE DEVELOPMENT. 11 11 106 11 0 0 6134304 5162453 925 6816 5108 42751 390577 406735 6530914 5618755 51267 33741 0 0 6874054 7480230 0 0 118503 3509783 3981547 10435104 11495518 -3904190 -5876763 21360540 16806789 674993 1031801 20685547 15774988 X PACIFIC NORTHWEST RESEARCH INSTITUTE (PNRI), A NONPROFIT CORPORATION, IS AN INDEPENDENT, BIOMEDICAL RESEARCH INSTITUTE CONDUCTING BASIC AND APPLIED RESEARCH AIMED AT UNDERSTANDING HOW HEALTH IS MAINTAINED IN THE FACE OF GENETIC AND ENVIRONMENTAL RISKS ASSOCIATED WITH DISEASE DEVELOPMENT. THE SCIENTIFIC DISCOVERIES HAVE APPLICABILITY IN A VARIETY OF DISEASES, INCLUDING DIABETES, CANCER, NEUROLOGICAL DISORDERS, AMONG MANY OTHERS. 0 0 4122755 THE CARVALHO LAB STUDIES HOW, WHEN, AND WHY HUMAN GENOMIC VARIANTS OCCUR AND CONTRIBUTE TO THE DEVELOPMENT OF DISEASE AND DISABILITY. 3208639 THE HAGOPIAN LAB RESEARCHES WAYS TO PREDICT AND PREVENT THE DEVELOPMENT OF TYPE 1 DIABETES, A DISEASE AFFECTING OVER ONE MILLION AMERICAN CHILDREN AND ADULTS. NOT EVERYONE WITH GENETIC RISK FOR TYPE 1 DIABETES DEVELOPS THE DISEASE. WHY NOT? SCIENTISTS IN THE HAGOPIAN LAB BELIEVE ANSWERS LIE IN THE ENVIRONMENT. THEY ARE ONE OF 6 LABS PARTICIPATING IN AN INTERNATIONAL STUDY FOLLOWING 8,000 CHILDREN WITH HIGH GENETIC RISK FOR TYPE 1 DIABETES. THE HAGOPIAN LAB ALSO DEVELOPS POPULATION BASED NEWBORN SCREENING METHODS TO PREDICT WHO IS AT RISK. THE ULTIMATE GOAL IS TO PREVENT THE DISEASE ENTIRELY. 1887107 33741 EXPERIMENTING IN YEAST ALLOWS THE DUDLEY LAB TO MAKE DISCOVERIES THAT GO BEYOND THE LAB WITH THE POWER TO CHANGE HOW SCIENTISTS AROUND THE GLOBE APPROACH GENETIC RESEARCH. FROM PERFORMING LARGESCALE EXPERIMENTS TO DISCOVERING NEW ANTIFUNGAL TREATMENTS, THE DUDLEY LAB IS A WORLD LEADER IN USING YEAST TO ANSWER FUNDAMENTAL QUESTIONS ABOUT BIOLOGY. WE ARE PASSIONATE ABOUT APPLYING AND DEVELOPING NOW TECHNOLOGIES AND ABOUT TRANSLATING DISCOVERIES FROM OUR LAB INTO REALWORLD APPLICATIONS. THE DUDLEY LAB EXPERIMENTS IN YEAST BECAUSE YEAST CELLS FUNCTION IN MUCH THE SAME WAY AS HUMAN CELLS. HOWEVER, WITH YEAST, WE CAN PERFORM EXPERIMENTS MUCH FASTER, AND ON A GRANDER SCALE, THAN SCIENTISTS CAN WITH HUMAN CELLS. 1571731 6816 THE STUBBS LAB IS FOCUSED ON UNDERSTANDING HOW THE INTERPLAY BETWEEN GENES AND ENVIRONMENT SHAPES BRAIN DEVELOPMENT, AND HOW THAT INTERPLAY ULTIMATELY INFLUENCES BEHAVIOR. WE STUDY THE FOLE OF GENE REGULATION THE PROCESSES RESPONSIBLE FOR ORCHESTRATING HOW GENES ARE USED IN EACH BRAIN CELL TO SPECIFY UNIQUE FUNCTIONS AND HOW WHAT HAPPENS DURING OUR LIFETIME LEADS TO CHANGES IN THOSE PROCESSES. 1571731 6816 10790232 1 1 0 0 0 0 0 0 0 1 1 0 0 1 1 0 1 0 0 0 0 0 0 0 0 0 0 0 1 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 33 0 106 1 0 0 0 0 0 0 0 0 0 0 0 0 X 11 11 0 0 0 0 0 0 0 1 1 0 0 0 1 1 1 1 1 1 1 0 WA X DIONNE GORDON 2067261200 720 BROADWAY SEATTLE WA 98122 GARY KOCHER CHAIR 2.00 X X 0 0 0 ALLISON HANDY SECRETARY 2.00 X X 0 0 0 MATTHEW GAGNIER TREASURER 2.00 X X 0 0 0 JIM CONGDON BOARD MEMBER 1.00 X 0 0 0 TERA EERKES BOARD MEMBER 2.00 X 0 0 0 ASH GUNDERSON BOARD MEMBER 1.00 X 0 0 0 CINDY HABA BOARD MEMBER 2.00 X 0 0 0 THOMAS HAYWARD BOARD MEMBER 2.00 X 0 0 0 STEPHAN MARTINEZ BOARD MEMBER 2.00 X 0 0 0 LINDA MAUZY BOARD MEMBER 2.00 X 0 0 0 SHIRIN MCCONAGHY BOARD MEMBER 2.00 X 0 0 0 JOHN WECKER CEO 40.00 X 294850 0 31400 ANSLEY LUCAS CFO 40.00 X 153888 0 4253 AIMEE DUDLEY SR INVESTIGATOR 40.00 X 197149 0 0 WILLIAM HAGOPIAN SR INVESTIGATOR 40.00 X 219420 0 26150 DAVID GALAS SR INVESTIGATOR 40.00 X 297825 0 0 LISA STUBBS SR INVESTIGATOR 40.00 X 233411 0 27000 MICHAEL METZGER ASST INVESTIGATOR 40.00 X 133969 0 26111 RICK MCLAUGHLIN ASST INVESTIGATOR 40.00 X 147105 0 4464 CLAUDIA FONSECA ASST INVESTIGATOR 40.00 X 134429 0 4152 JUSTIN DUKES DIR OF OPERATIONS 40.00 X 151419 0 0 MICHAEL KILLIAN CLINICAL RESEARCH MGR 40.00 X 108659 0 7527 2072124 0 131057 11 0 1 0 CLARK NUBER PS 10900 NE 4TH ST SUITE 1400 BELLEVUE WA 98004 CONSULTING 125950 LAY COMMERCIAL ROOFING LLC 10735 A ST SUITE D TACOMA WA 98444 FACILITIES RE-ROOFING PROJECT 107376 2 3889071 1273382 37662 5162453 VIVARIUM REVENUE 900099 6816 6816 6816 42751 42751 424441 43774 380667 380667 380667 IRS REFUND 900099 13344 13344 REBATES 900099 12724 12724 26068 5618755 6816 0 449486 X 33741 33741 1485349 1394297 91052 4563476 4283735 218353 61388 29145 27358 652 1135 951704 893364 48457 9883 450556 422937 22978 4641 92302 86644 4707 951 89139 83675 4546 918 1683821 1580603 85875 17343 330 310 17 3 90307 84772 4605 930 610807 570682 33384 6741 39406 36991 2011 404 13666 12828 697 141 487512 457628 24863 5021 REPAIRS & MAINTENANCE 397414 373053 20268 4093 DUES & SUBSCRIPTIONS 79792 74901 4069 822 PUBLICATION FEES 69508 65247 3545 716 EQUIPMENT RENT, MAINT. 63861 59948 3256 657 263682 247518 13448 2716 11495518 10790232 586783 118503 313761 169049 8740223 4375645 676166 565634 533565 123293 11530 4500 386213 199460 15071341 11257818 4091390 3813523 2052016 2520557 42793 45783 4512883 4989345 21360540 16806789 618575 920057 43704 100000 12714 11744 674993 1031801 X 15686420 10291892 4999127 5483096 20685547 15774988 21360540 16806789 X -5876763 489742 476462 X 0 1 X 1 1 1 X 4266327 20450636 6597150 6134304 5162453 42610870 4266327 20450636 6597150 6134304 5162453 42610870 15601506 27009364 580512 482111 463827 439218 467192 2432860 3585 1389 9005 6439 26068 46486 45090216 11986 0.59900 0.61080 X SCHEDULE A, PART II, LINE 10, EXPLANATION OF OTHER INCOME: MISCELLANEOUS INCOME - 2019 AMOUNT: $ 846. 2021 AMOUNT: $ 17. 2022 AMOUNT: $ 13,344. REBATES - 2018 AMOUNT: $ 3,585. 2019 AMOUNT: $ 543. 2020 AMOUNT: $ 9,005. 2021 AMOUNT: $ 6,422. 2022 AMOUNT: $ 12,724. RESTRICTED RESTRICTED RESTRICTED RESTRICTED RESTRICTED RESTRICTED RESTRICTED RESTRICTED 475000 20466 20466 475000 75000 400000 347 347 475000 75000 164 164 75000 75000 131 131 75000 85082 -10057 25 75000 0.00000 1.00000 0.00000 1 0 823359 823359 9684695 7580994 2103701 4563287 3676824 886463 3813523 BENEFICIAL INTEREST IN PERPETUAL TR 4989345 4989345 ANNUITY PAYABLE 1494 TENANT DEPOSITS 10250 11744 6628733 489742 476462 966204 5662529 -43774 -43774 5618755 11539292 43774 43774 11495518 0 11495518 PART V, LINE 4: THE ORGANIZATION'S ENDOWMENT FUNDS ARE DESIGNATED FOR USE AS OPERATING RESERVES AND SCIENTIST RECRUITMENT. PART XI, LINE 2D - OTHER ADJUSTMENTS: GAIN ON PERPETUAL TRUST 476,462. PART XI, LINE 4B - OTHER ADJUSTMENTS: RENTAL EXPENSES -43,774. PART XII, LINE 2D - OTHER ADJUSTMENTS: RENTAL EXPENSES 43,774. 1 TUITION 3 33741 COST TUITION REDUCTION PAYMENTS PART I, LINE 2: THE ORGANIZATION HAS A FORMAL AGREEMENT WITH A UNIVERSITY WHICH INCLUDES TUITION REDUCTION FOR STUDENTS WHO WORK AT PNRI LABS. X X X X 0 0 0 0 0 0 0 0 0 JOHN WECKER CEO 294850 0 0 0 0 0 27000 0 4400 0 326250 0 0 0 DAVID GALAS SR INVESTIGATOR 297825 0 0 0 0 0 0 0 0 0 297825 0 0 0 LISA STUBBS SR INVESTIGATOR 233411 0 0 0 0 0 27000 0 0 0 260411 0 0 0 WILLIAM HAGOPIAN SR INVESTIGATOR 219420 0 0 0 0 0 26150 0 0 0 245570 0 0 0 AIMEE DUDLEY SR INVESTIGATOR 197149 0 0 0 0 0 0 0 0 0 197149 0 0 0 MICHAEL METZGER ASST INVESTIGATOR 133969 0 0 0 0 0 20325 0 5786 0 160080 0 0 0 ANSLEY LUCAS CFO 153888 0 0 0 0 0 853 0 3400 0 158141 0 0 0 RICK MCLAUGHLIN ASST INVESTIGATOR 147105 0 0 0 0 0 4464 0 0 0 151569 0 0 0 JUSTIN DUKES DIR OF OPERATIONS 151419 0 0 0 0 0 0 0 0 0 151419 0 0 0 X 1 37662 FAIR MARKET VALUE 0 0 1 0 PART I, COLUMN (B): NUMBER OF CONTRIBUTIONS RECEIVED. FORM 990, PART I, LINE 6: VOLUNTEERS CONSIST OF UNCOMPENSATED BOARD MEMBERS WHO GAVE THEIR TIME DURING THE YEAR. FORM 990, PART VI, SECTION B, LINE 11B THE INTERIM CEO, CFAO, CHIEF ADVANCEMENT OFFICER AND FINANCE COMMITTEE CHAIR WILL REVIEW THE FORM 990 PRIOR TO FILING WITH THE IRS. THE PUBLIC DISCLOSURE COPY WILL BE DISTRIBTED AND DISCUSSED AT A SUBSEQUENT BOARD MEETING. ELECTRONIC COPIES OF THE PUBLIC DISCLOSURE VERSION OF FORM 990 WILL BE DISTRIBUTED TO THE ENTIRE BOARD, AND PHYSICAL COPIES OF THE FULL FORM 990 WILL BE MADE AVAILABLE ONSITE UPON REQUEST. FORM 990, PART VI, SECTION B, LINE 12C ANNUALLY, PER INSTITUTE CONFLICT OF INTEREST POLICY THE FINANCE & AUDIT COMMITTEE SUBMITS A BOARD QUESTIONNAIRE TO ALL TRUSTEES AND KEY STAFF. ALL RESPONSES ARE GATHERED AND REVIEWED BY THE COMMITTEE CHAIR AND THE CFAO. THE RESULTS ARE DISCUSSED AT THE FINANCE & AUDIT COMMITTEE MEETING. THE COMMITTEE CHAIR THEN PRESENTS THE RESULTS TO THE FULL BOARD AND ACTION IS TAKEN AS NEEDED. IF A POTENTIAL CONFLICT OF INTEREST AROSE DURING THE YEAR, THE BOARD MEMBER WOULD CONTACT OUR COMMITTEE CHAIR AND DISCLOSE THE MATTER AND BOARD REVIEW AND ACTION WOULD BE TAKEN AT THE NEXT MEETING TO ALERT ALL MEMBERS. FORM 990, PART VI, SECTION B, LINE 15 THE CEO, CFAO, AND KEY EMPLOYEES HAVE THEIR INITIAL SALARY AND ANY NON-COST OF LIVING ADJUSTMENT INCREASES DOCUMENTED BY A SALARY SURVEY PROCESS CONDUCTED BY OUR INDEPENDENT HUMAN RESOURCES CONSULTING FIRM. IN ADDITION, THE CEO CONTRACT IS APPROVED BY BOARD EXECUTIVE COMMITTEE. COMPENSATION REVIEWS ARE PERFORMED ANNUALLY. FORM 990, PART VI, SECTION C, LINE 19 GOVERNING DOCUMENTS, CONFLICT OF INTEREST POLICY AND FINANCIAL STATEMENTS ARE AVAILABLE UPON REQUEST. FORM 990, PART IX, LINE 11G OTHER FEES: PROGRAM SERVICE EXPENSES 1,580,603. MANAGEMENT AND GENERAL EXPENSES 85,875. FUNDRAISING EXPENSES 17,343. TOTAL EXPENSES 1,683,821. FORM 990, PART XI, LINE 9: GAIN ON PERPETUAL TRUST 476,462.