2023-02-15T16:09:16-06:00 2021-12-31 320025877 ABARE KRESGE & ASSOCIATES CPAS 1200 PLANTATION ISLAND DRIVE ST AUGUSTINE FL 32080 990PF 2021-01-01 463383293 SCOTT R MACKENZIE FOUNDATION INC SCOT 8558166858 PO BOX 550750 JACKSONVILLE FL 322550750 SCOTT R MACKENZIE DIRECTOR 8558166858 2023-02-14 1 SCOTT MACKENZIE XXX-XX-XXXX WILLIAM T ABARE III CPA P00120073 9044600747 2023-02-14 3 AAL1 IAL1 2021 2023-03-07 01:45:13Z X 25356317 X X 32171 32171 366983 366983 1439459 4651912 1439459 1838613 1838613 76500 76500 0 2169 2169 0 23813 23813 0 28241 28241 0 527 527 6411 6411 0 233568 233568 0 371229 371229 0 1008269 1008269 1379498 371229 1008269 459115 1467384 25177 119354 119354 809684 279118 279118 254 150185 0 0 1357703 498854 504384 12014157 13960769 24445328 18302 18302 527 0 0 0 8133 8133 14357687 14866228 25356317 9000 23649 6000 35143 15000 58792 X 14342687 14807436 14342687 14807436 14357687 14866228 14342687 459115 5634 14807436 0 14807436 PUBLICLY TRADED SECURITIES 217265 174451 42814 42814 PUBLICLY TRADED SECURITIES 4386513 3038002 1348511 1348511 CAPITAL GAINS DIVIDENDS P 48134 48134 48134 1439459 20397 0 20397 0 20397 254 0 0 0 254 61 20204 0 0 0 0 0 0 0 0 0 0 1 1 FL 1 0 0 0 0 1 WWW.SCOTTRMACKENZIEFOUNDATION.COM ABARE KRESGE ASSOCIATES CPAS LL 9044600747 4237 SALISBURY ROAD 100 JACKSONVILLE FL 32216 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 SCOTT R MACKENZIE 4237 SALISBURY ROAD BLDG 1 130 JACKSONVILLE FL 32216 DIRECTOR 5.00 0 0 0 MELINDA A MACKENZIE 4237 SALISBURY ROAD BLDG 1 130 JACKSONVILLE FL 32216 DIRECTOR 3.00 0 0 0 LAWRENCE B MACKENZIE 4237 SALISBURY ROAD BLDG 1 130 JACKSONVILLE FL 32216 DIRECTOR 5.00 0 0 0 GERARDO CRUZ 4237 SALISBURY ROAD BLDG 1 130 JACKSONVILLE FL 32216 DIRECTOR 6.00 0 0 0 CAROLYN TUCKER 4237 SALISBURY ROAD BLDG 1 130 JACKSONVILLE FL 32216 EXEC. DIRECTOR 40.00 0 0 0 CAROLYN K TUCKER 4236 MELROSE AVE JACKSONVILLE FL 32210 MANAGER 40.00 76500 0 0 0 WELLS FARGO PO BOX HENDERSON NV 89009 INVESTMENT ADVISORY 114267 0 0 24297321 87897 254 24385472 0 0 24385472 365782 24019690 1200985 1200985 20397 20397 1180588 0 1180588 0 1180588 1008269 0 1008269 1180588 1008269 0 0 1008269 1008269 0 0 0 0 0 0 0 0 0 0 0 1180588 0 0 0 SCOTT R MACKENZIE CAROLYN TUCKER EXECUTIVE DIRECTOR PO BOX 550750 JACKSONVILLE FL 322550750 8558166858 INFO@SCOTTRMACKENZIEFOUNDATION.COM AN ELIGIBLE 501(C)(3) ORGANIZATION CAN GO TO WWW.SCOTTRMACKENZIEFOUNDATION.COM AND FOLLOW THE INSTRUCTIONS FOR APPLYING FOR A GRANT. INITIAL GRANT APPLICATION: APRIL 30TH; FINAL GRANT APPLICATION: JUNE 30TH FUNDING IS AVAILABLE FOR AMERICAN-BASED ORGANIZATIONS WITH A MISSION TO FIND A CURE FOR: CANCER LUNG DISEASE (INCLUDING ASTHMA) DIABETES HEART DISEASE MAYO CLINIC 4500 SAN PABLO RD S JACKSONVILLE FL 32224 PUBLIC THE BENEFACTOR DESIRES THAT GRANTEE SHALL USE THIS GIFT TO SUPPORT THE TAPESTRY STUDY. 9763 UNIVERSITY OF FLORIDA FOUNDATION PO BOX 14425 GAINESVILLE FL 32604 PUBLIC THE BENEFACTOR DESIRES THAT GRANTEE SHALL USE THE GIFT TO BROADEN THE DISCOVERY OF NEW PANCREATIC CANCER BIOMARKERS THROUGH GENOMIC SEQUENCING. BY SEQUENCING TUMOR AND NORMAL SAMPLES FROM OUR PATIENTS, WE CAN DETERMINE NOVEL CANCER DRIVERS INCLUDING MUTATIONS, FUSIONS, AND GENE EXPRESSION ALTERATIONS THAT DRIVE THESE CANCERS. NEW BIOMARKERS WILL INTRODUCE NEW POTENTIAL TARGETS FOR TREATMENT AND EARLY DETECTIONS. 150000 UNIVERSITY OF FLORIDA FOUNDATION PO BOX 14425 GAINESVILLE FL 32604 PUBLIC THE BENEFACTOR DESIRES THAT GRANTEE SHALL USE THE GIFT TO ASSESS POTENTIAL DRUG INTERACTIONS BETWEEN CANGRELOR AND NOVEL P2Y12 INHIBITORS AND EVALUATE THE IMPACT OF RECEPTOR EXPRESSION ON THEIR FINDINGS. 125000 ISRAEL CANCER RESEARCH FUND 52 VANDERBILT AVE SUITE 1510 NEW YORK NY 10017 PUBLIC THE BENEFACTOR DESIRES THAT GRANTEE SHALL USE THE GIFT TO ASK HOW DNA REPAIR IS ORCHESTRATED DESPITE THE PACKAGING OF DNA INTO CHROMATIN. SWI/SNF PROTEINS ESTABLISH AND MAINTAIN CHROMATIN STRUCTURE. SUBUNITS OF SWI/SNF PROTEINS ARE MUTATED IN 20% OF CANCERS, IMPLICATING THEM IN CARCINOGENESIS, AND MAKING THEM ATTRACTIVE CANDIDATES FOR CANCER-SPECIFIC AND SELECTIVE THERAPIES. DR. ADAR EXPECTS TO ESTABLISH THAT SWI/SNF REMODELERS FACILITATE SPECIFIC STEPS IN NUCLEOTIDE EXCISION REPAIR (NER) IN CHROMATIN TEMPLATES, AND THAT CANCER ASSOCIATED MUTANTS ARE DEFICIENT IN THIS FUNCTION. THIS NEW UNDERSTANDING OF SWI/SNF FUNCTIONS CAN THEN BE LEVERAGED TO DESIGN NEW CANCER DIAGNOSTICS AND CHEMOTHERAPEUTICS. 148500 MOUNT DESERT ISLAND BIOLOGICAL LABORATORY 159 OLD BAR HARBOR RD BAR HARBOR ME 04609 PUBLIC THE BENEFACTOR DESIRES THAT GRANTEE SHALL USE THE GIFT TO PREVENT ORGAN COMPLICATIONS IN DIABETIC PATIENTS. HIGH GLUCOSE LEVELS LEAD TO THE PATHALOGICAL CHANGES IN THE VASCULATURE OF DIFFERENT ORGANS SUCH AS THE HEART, KIDNEY, EYE AND PERIPHERAL CIRCULATION. THE FOCUS IS THE MICROCIRCULATION OF THE KIDNEY. THE ENDOTHELIAL CELL SURFACE IS COVERED WITH A LAYER OF GLYCOCALYX. THE GLYCOCALYX IS VERY IMPORTANT FOR THE HEALTH OF THE VASCULAR WALL AND REGULATES CENTRAL MECHANISMS SUCH AS METABOLISM, INFLAMMATION, BLOOD PRESSURE, ETC. WE WILL TEST THE HYPOTHESIS THAT RECOMBINANT HPA2 AMELIORATES DIABETIC NEPHROPATHY BY MAINTAINING A FUNCTIONAL HEPARAN SULFATE GLYCOCALYX ON ENDOTHELIAL CELLS AND MONOCYTES. 400000 UNIVERSITY OF ARIZONA 1501 N CAMPBELL AVE TUCSON AZ 85724 PUBLIC THE BENEFACTOR DESIRES THAT GRANTEE SHALL USE THE GIFT TO IMPROVE THE DIAGNOSIS AND TREATMENT OF ATRIAL FIBRILLATION. TO DEVELOP PATIENT-SPECIFIC TARGETED NEXT-GENERATION GENE SEQUENCING FOR PREDICTING AND DIAGNOSING ATRIAL FIBRILLATION AND ESTABLISH A PATIENT-SPECIFIC STEM CELL PLATFORM FOR DEVELOPING PRECISION MEDICINE BASED TREATMENTS. 175006 1008269 0 14 32171 14 366983 901101 1391325 14 48134 1391325 447288 0 1838613 0 0 0 0 0 0 0 0 0 0 AMERIPRISE FINL. IN 250742 251422 US BANK CORP 248112 252962 INVESCO QQQ TRUST AT COST 591201 2719305 ISHARES GOLD TRUST AT COST 1 388862 ISHARES RUSSELL ETF MIDCAP AT COST 470366 1049246 ISHARES TR RUSSELL 1000 AT COST 743053 1934305 ISHARES TR RUSSELL 3000 AT COST 199676 514762 VANGUARD DIVIDEND APPRECIATION ETF AT COST 339998 714480 DODGE & COX INCOME FD COM AT COST 2370000 2297661 ISHARES CORE TOTAL US AGGREGATE BOND AT COST 1350054 1345916 CROWN CASTLE INTERNATIONAL CORP AT COST 27927 35695 COCA-COLA AT COST 9622 10954 GENERAL MILLS AT COST 17827 19608 KIMBERLY CLARK CORP AT COST 19214 19723 PEPSICO AT COST 8611 10770 PHILLIP MORRIS AT COST 33848 42180 CHEVRON AT COST 35942 51517 EXXON MOBIL AT COST 29627 46749 HUNTINGTON BANCSHARES AT COST 16518 26492 REGIONS FIN AT COST 8300 11162 ABBVIE AT COST 37994 56326 AMGEN AT COST 24028 23622 BRISTOL MYERS SQUIBB AT COST 16458 16772 GILEAD SCIENCES AT COST 37444 42041 HEALTHCARE SELECT SECTOR SPDR AT COST 285258 501005 MERC & CO AT COST 39092 38473 PFIZER AT COST 13618 21494 3M CO AT COST 13309 14210 ISHARES US TECHNOLOGY AT COST 120456 640466 AT&T AT COST 18571 16015 VERIZON AT COST 40016 35177 AMERICAN ELECTRIC POWER AT COST 27446 29271 DOMINION ENERGY AT COST 27147 27339 DUKE ENERGY AT COST 27868 33778 PPL CORPORATION AT COST 15793 16924 PUBLIC SYSTEM ENTERPRISE GROUP AT COST 9608 11678 SOUTHERN CO AT COST 30147 37513 BCE AT COST 31922 39290 BRITISH AMERICAN TOBACCO AT COST 45437 47885 CANADIAN IMPERIAL AT COST 13400 20748 ENBRIDGE AT COST 29725 36305 NATIONAL GRID AT COST 26073 32255 TC ENERGY CO AT COST 17326 18058 UNILEVER AT COST 40901 37223 VODAFONE GROUP AT COST 27241 28083 ISHARES CORE S&P MID-CAP ETF AT COST 274199 591354 ISHARES RUSSELL 2000 ETF AT COST 503292 1060864 SCHWAB US KARG CAP ETF AT COST 667759 1422750 SCHWAB US REIT ETF AT COST 350300 620899 SPDR S&P 500 ETF TRUST AT COST 1042582 2010031 VANGUARD VALUE VIPE AT COST 702330 1263234 ISHARES MSCI EAFE VALUE ETF AT COST 480412 751567 VANGUARD INTERNATIONAL GROWTH FUND AT COST 111121 197419 ISHARES PREFERRED AND INCOME SEC EFT AT COST 250431 250381 VANGUARD SHORT TERM INVEST GRADE AT COST 975000 957224 DIGITAL REALTY TR INC AT COST 10002 13619 REALTY INCOME CORP AT COST 15809 16394 CONAGRA BRANDS AT COST 11357 11269 WALGREENS BOOT ALLIANCE AT COST 11061 11631 WILLIAMS COS INC AT COST 23933 23306 TRUIST BANK AT COST 18076 19497 US BANK CORP AT COST 20046 20839 LOOKHEAD MARTIN AT COST 11185 11728 ISHARES CORE S&P TOTAL US STOCK EFT AT COST 932272 1882848 SPDR BLOOMBERG BARCLAYS CONV SEC AT COST 250776 236436 TOTAL ENERGIES SE AT COST 10763 10683 ORION OFFICE REIT AT COST 0 17 LEGAL 23813 23813 0 INVESTMENT INCOME RECEIVABLE 0 8133 8133 BANK CHARGES 4622 4622 0 COMPUTER NETWORK AND WEBSITE EXPENSE 19406 19406 0 INSURANCE 5531 5531 0 INTERNET 1377 1377 0 INVESTMENT ADVISORY FEES 114267 114267 0 OFFICE EXPENSE 32 32 0 PAYROLL PROCESSING FEES 1541 1541 0 TELEPHONE 1410 1410 0 DIRECTOR FEES 75000 75000 0 IT & DOCUMENT STORAGE 330 330 0 MEMBERSHIP AND DUES 31 31 0 OPERATIONS 10021 10021 0 BASIS ADJUSTMENT 5634 FEDERAL WITHHOLDINGS TAX PAYABLE 6000 15000 EXCISE TAX PAYABLE 0 20143 EXCISE TAXES 20397 20397 0 PAYROLL TAXES 5901 5901 0 FOREIGN TAXES 1943 1943 0