2022-08-15T11:05:57-05:00 2021-09-30 861065772 DELOITTE TAX LLP 695 TOWN CENTER DRIVE SUITE 1000 COSTA MESA CA 92626 990 2020-10-01 330435954 THE SCRIPPS RESEARCH INSTITUTE SCRI 8587841000 10550 NORTH TORREY PINES ROAD LA JOLLA CA 92037 JARED MACHADO CHIEF ACCOUNTING OFFICER 8587841000 2022-08-15 1 JARED MACHADO XXX-XX-XXXX JOHN W SADOFF JR P00540589 7144367100 3 AAL1 IAL1 2020 2022-09-23 18:48:47Z PETER SCHULTZ PHD 10550 NORTH TORREY PINES ROAD LA JOLLA CA 92037 1184528263 0 X WWW.SCRIPPS.EDU X 1924 CA TSRI CONDUCTS BIOMEDICAL AND BIOCHEMICAL RESEARCH AND POSTGRADUATE TRAINING PROGRAMS. 18 17 2160 17 270057 0 361859000 418691076 2222378 2261518 22451990 39422523 28313244 76712642 414846612 537087759 14124814 82523976 0 0 204838315 217363929 2492 0 4814405 225038263 173956048 444003884 473843953 -29157272 63243806 973580297 1160188604 321951842 438180180 651628455 722008424 X THE SCRIPPS RESEARCH INSTITUTE ("TSRI") PERFORMS HIGH IMPACT BASIC BIOMEDICAL RESEARCH, IMPROVES THE HUMAN CONDITION BY FOSTERING TRANSLATION OF ITS DISCOVERIES INTO USEFUL PRODUCTS AND ENGAGES IN THE HIGHEST QUALITY GRADUATE SCIENTIFIC EDUCATION AND POST GRADUATE SCIENTIFIC TRAINING. TSRI IS KNOWN FOR ITS ENTREPRENEURIAL ENVIRONMENT AND ITS EMPHASIS IN RESEARCH RELATING TO SYNTHETIC CHEMISTRY, THE RELATIONSHIP BETWEEN MOLECULAR STRUCTURE AND ACTIVITY AND CHEMICAL BIOLOGY. 0 0 414399052 68494653 2261518 GROUNDBREAKING SCIENTIFIC RESEARCH IS CONDUCTED AT TSRI CAMPUSES IN LA JOLLA, CALIFORNIA, AND JUPITER, FLORIDA, SUPPORTED BY GRANTS, CONTRACTS AND FELLOWSHIPS FROM PUBLIC AND PRIVATE INSTITUTES AND INDIVIDUALS. TSRI'S UNIQUE STRUCTURE MERGES BASIC SCIENTIFIC STUDIES IN BIOLOGY, CHEMISTRY AND BIOINFORMATICS WITH TRANSLATIONAL SCIENCE TO PRODUCE THE NEXT GENERATION OF DRUGS AND ADVANCES IN DIGITAL AND PRECISION MEDICINE. SCIENTIFIC DISCOVERIES AT TSRI SEED JOINT DRUG DISCOVERY PROJECTS AT CALIBR, A DIVISION OF TSRI, CREATING A PIPELINE OF DRUG CANDIDATES THAT WILL IMPACT PATIENTS FOR YEARS TO COME. THE SCRIPPS RESEARCH TRANSLATIONAL INSTITUTE, ANOTHER DIVISION OF TSRI, AIMS TO INDIVIDUALIZE HEALTHCARE BY LEVERAGING THE PROGRESS BEING MADE IN HUMAN GENOMICS AND COMBINING IT WITH THE POWER OF WIRELESS DIGITAL TECHNOLOGIES AND ARTIFICIAL INTELLIGENCE. 26127330 14029323 TSRI IS COMMITTED TO EDUCATING, TRAINING AND INSPIRING THE SCIENTISTS OF TOMORROW. THE INSTITUTE'S SKAGGS GRADUATE SCHOOL OF CHEMICAL AND BIOLOGICAL SCIENCES, RANKED ONE OF THE TEN BEST GRADUATE PROGRAMS IN THE COUNTRY, EMPOWERS STUDENTS TO MAKE HIGH-IMPACT DISCOVERIES AT THE INTERFACE OF CHEMISTRY AND BIOLOGY. STUDENTS IN THE SKAGGS GRADUATE SCHOOL ARE IMMERSED IN INTENSIVE LABORATORY RESEARCH FROM DAY ONE AND PURSUE AMBITIOUS INVESTIGATIONS ACROSS SCIENTIFIC DISCIPLINES. GRADUATES OF THE SCHOOL BECOME EDUCATORS AT TOP UNIVERSITIES AND RESEARCH INSTITUTES, THOUGHT LEADERS WITHIN GOVERNMENT DEPARTMENTS AND INNOVATORS AT PHARMACEUTICAL AND BIOTECHNOLOGY COMPANIES. POSTDOCTORAL ASSOCIATES ARRIVE AT TSRI FROM ALL OVER THE GLOBE, SEEKING TO EXPAND THEIR KNOWLEDGE AND TRAINING BY WORKING ALONGSIDE OUR WORLD-RENOWNED SCIENTISTS. THE SCRIPPS FELLOWS PROGRAM IDENTIFIES INDIVIDUALS WITH AN OUTSTANDING RECORD OF GRADUATE RESEARCH AND MOVES THEM INTO THEIR OWN LABORATORIES, ALLOWING THEM TO LEAPFROG THEIR POSTDOCTORAL YEARS OF STUDY AND BEGIN PUSHING THE FRONTIERS OF SCIENTIFIC DISCOVERY. 440526382 1 1 0 0 0 0 0 0 0 1 1 1 0 0 1 0 1 0 0 0 1 1 0 0 0 0 0 1 1 1 1 0 0 0 0 0 0 0 0 0 0 1 0 0 0 1 1 1 1 0 0 1 332 0 1 2160 1 1 1 0 0 0 0 0 0 0 0 0 1 0 X 18 17 0 0 0 0 0 0 0 1 1 0 0 1 1 1 1 1 1 1 1 0 AK AL CA CO DC FL GA HI IL KS KY MA MD MI MN MS NC NH NJ NM NY OH OR PA RI SC TN UT VA WI WV X JARED MACHADO 8587841000 10550 N TORREY PINES DRIVE LA JOLLA CA 92037 PETER G SCHULTZ PRESIDENT/CEO 40.00 0.00 X X 936779 0 72139 JEFFREY KELLY DIRECTOR/PROFESSOR (END 09/21) 40.00 0.00 X 379393 0 71406 BENEDICT GROSS DIRECTOR 1.00 0.00 X 0 0 0 BERNARD SAINT-DONAT PHD DIRECTOR 1.00 0.00 X 0 0 0 CHRISTOPHER T WALSH DIRECTOR 1.00 0.00 X 0 0 0 CLAUDIA S LUTTRELL DIRECTOR 1.00 0.00 X 0 0 0 GE LI DIRECTOR 1.00 0.00 X 0 0 0 GERALD CHAN DIRECTOR 1.00 0.00 X 0 0 0 HERBERT WERTHEIM DIRECTOR (START 02/21) 1.00 0.00 X 0 0 0 JOANNE STUBBE DIRECTOR (START 02/21) 1.00 0.00 X 0 0 0 JOHN D DIEKMAN BOARD CHAIR 1.00 0.00 X X 0 0 0 JOHN MARTIN DIRECTOR (END 05/21) 1.00 0.00 X 0 0 0 LILLIAN LOU DIRECTOR (START 06/21) 1.00 0.00 X 0 0 0 MARK EDWARDS DIRECTOR 1.00 0.00 X 0 0 0 MARK PEARSON DIRECTOR 1.00 0.00 X 0 0 0 PETER C FARELL PHD D SC DIRECTOR 1.00 0.00 X 0 0 0 RON BURKLE DIRECTOR 1.00 0.00 X 0 0 0 SHERRY LANSING DIRECTOR 1.00 0.00 X 0 0 0 TOM DANIEL DIRECTOR (START 10/20) 1.00 0.00 X 0 0 0 WILLIAM R HEARST III DIRECTOR 1.00 0.00 X 0 0 0 MATTHEW S TREMBLAY CHIEF OPERATING OFFICER 40.00 0.00 X 619874 0 74755 JARED M MACHADO TREASURER (END 10/20)/CAO 40.00 0.00 X 364993 0 76429 ALICE T FENG TREASURER (START 10/20)/CFO 40.00 0.00 X 357946 0 70666 DEMETRIOS I ANDRIKOS SEC/VP LEGAL/GEN COUNSEL (END 01/21) 40.00 0.00 X 299186 0 73451 MARY WANG ASSISTANT SECRETARY 40.00 0.00 X 175341 0 27194 ALANNA RUTAN SEC./CHIEF COMP. OFF. (START 02/21) 40.00 0.00 X 146156 0 23130 JAMES R WILLIAMSON VP RSCH & ACADEMIC AFFAIRS 40.00 0.00 X 426678 0 71920 DOUGLAS A BINGHAM EVP SCRIPPS FL 40.00 0.00 X 309773 0 70003 KELLY SAN GEORGE CFO VP ADM. CALIBR 40.00 0.00 X 249114 0 50528 ERIC TOPOL PROFESSOR/EXEC VP 40.00 0.00 X 1057873 0 70338 VADIM KLYUSHNICHENKO VP PHARMACEUTICAL DEV & QUAL 40.00 0.00 X 397030 0 92276 PAMELA GARZONE CHIEF MEDICAL OFFICER 40.00 0.00 X 404594 0 63790 JENNIFER CROSBY VP PHILANTHROPY 40.00 0.00 X 369268 0 73553 KARL SHARPLESS PROFESSOR 40.00 0.00 X 365061 0 71030 6859059 0 1052608 369 0 1 1 SCHWEGMAN LUNDBERG WOESSNER PA 121 SOUTH EIGHT STREET MINNEAPOLIS MN 55402 LEGAL SERVICES 540597 BEHMER & BLACKFORD LLP 12526 HIGH BLUFF DRIVE SUITE 300 SAN DIEGO CA 92130 LEGAL SERVICES 513719 DELOITTE & TOUCHE LLP P O BOX 844708 DALLAS TX 75284 AUDIT & TAX SERVICES 432477 COOLEY LLP 101 CALIFORNIA ST FIFTH FLOOR SAN FRANCISCO CA 94111 LEGAL SERVICES 361152 WILSON SONSINI GOODRICH & ROSATI PO BOX 742866 LOS ANGELES CA 90074 LEGAL SERVICES 256929 13 272180680 146510396 2088733 418691076 PATENT OFFICE 900099 2261518 2261518 2261518 2706277 270057 2436220 73615553 73615553 753942 661905 92037 92037 92037 683478251 16594 646716098 62501 36762153 -45907 36716246 36716246 SHARED SRVCS-SCRIPPS H 900099 429738 429738 2575314 2575314 3005052 537087759 2261518 270057 115865108 X 67286299 67286299 14029323 14029323 1208354 1208354 4764214 882637 3881577 178350856 167148638 9436581 1765637 -10884019 -10051267 -735274 -97478 32002278 30163324 1478894 360060 13130600 12125960 887042 117598 49821370 47288944 1938727 593699 3618331 3317796 125718 174817 8884814 6999967 1789531 95316 900048 862781 33768 3499 1897469 1897469 30825705 30823266 2439 3622938 2855066 5522 762350 PROFESSIONAL SERVICES 31645356 24727452 6595461 322443 LAB SUPPLIES 30546781 27323052 3065619 158110 UTILITIES 12193236 11637321 555915 473843953 440526382 28503166 4814405 98947927 196423177 63831920 73942523 551089 483949 1105159 1184571 26023324 23170563 811288574 509320492 306928752 301968082 234582399 291006964 236717854 223115953 681429 530000 4210444 48362822 973580297 1160188604 59137780 79866253 165535637 166769573 27535797 24615041 38485000 106075000 31257628 60854313 321951842 438180180 X 414325811 448091646 237302644 273916778 651628455 722008424 973580297 1160188604 X 63243806 7136310 -147 X 0 1 X 1 1 1 X 315969113 347588971 366278398 361859000 418691076 1810386558 315969113 347588971 366278398 361859000 418691076 1810386558 42785593 1767600965 14626349 22130806 36426682 33129194 77075770 183388801 1202834 1329949 978397 1742646 3005052 8258878 2002034237 0.88290 0.92050 X SCHEDULE A, PART II, LINE 10, EXPLANATION OF OTHER INCOME: OTHER INCOME - 2016 AMOUNT: $ 1,202,834. 2017 AMOUNT: $ 1,329,949. 2018 AMOUNT: $ 978,397. 2019 AMOUNT: $ 1,742,646. 2020 AMOUNT: $ 3,005,052. RESTRICTED RESTRICTED RESTRICTED RESTRICTED RESTRICTED RESTRICTED RESTRICTED RESTRICTED 124417627 22228447 1930910 665936 147911048 112171714 12416199 831736 1002022 124417627 99581986 13237745 361209 1009226 112171714 69583647 29168940 888030 58631 99581986 72652489 3182125 2132475 8383442 69583647 0.12000 0.88000 0.00000 0 0 43352136 43352136 456613276 254915798 201697478 22609779 21838059 771720 283240158 228922959 54317199 5473225 3643676 1829549 301968082 INVESTMENT IN LIMITED PARTNERSHIPS 223115953 F 223115953 PENSION LIABILITY 14307607 LEASE LIABILITY 46279655 UNITRUST 267051 60854313 544931880 7136310 707811 7844121 537087759 0 537087759 474551764 707811 707811 473843953 0 473843953 PART V, LINE 4: INVESTMENT RETURN FROM THE ENDOWMENTS SUPPORTS SCIENTIFIC PROJECTS CONSISTENT WITH THE MISSION AND PRINCIPLES OF THE SCRIPPS RESEARCH INSTITUTE. PART XI, LINE 2D - OTHER ADJUSTMENTS: RENTAL EXPENSES NETTED AGAINST RENTAL REVENUE 661,905. LOSS ON DISPOSAL OF EQUIPMENT 45,906. PART XII, LINE 2D - OTHER ADJUSTMENTS: RENTAL EXPENSES NETTED AGAINST RENTAL REVENUE 661,905. LOSS ON DISPOSAL OF EQUIPMENT 45,906. 1 EAST ASIA AND THE PACIFIC 0 0 PROGRAM SERVICES GRANTS FOR SCIENTIFIC RESEARCH 53826 EUROPE (INCLUDING ICELAND & GREENLAND) 0 0 PROGRAM SERVICES GRANTS FOR SCIENTIFIC RESEARCH 457945 NORTH AMERICA 0 0 PROGRAM SERVICES GRANTS FOR SCIENTIFIC RESEARCH 112699 SUB-SAHARAN AFRICA 0 0 PROGRAM SERVICES GRANTS FOR SCIENTIFIC RESEARCH 583884 CENTRAL AMERICA AND THE CARIBBEAN 0 0 INVESTMENTS 32564413 0 0 0 0 0 0 33772767 0 33772767 EAST ASIA AND THE PACIFIC - AUSTRALIA, BRUNEI, BURMA, CAMBODIA, GRANTS FOR SCIENTIFIC RESEARCH 53826 ELECTRONIC FUND/WIRE TRANSFER 0 EUROPE (INCLUDING ICELAND & GREENLAND) - ALBANIA, ANDORRA, AUSTRIA, BELGIUM GRANTS FOR SCIENTIFIC RESEARCH 21600 ELECTRONIC FUND/WIRE TRANSFER 0 EUROPE (INCLUDING ICELAND & GREENLAND) - ALBANIA, ANDORRA, AUSTRIA, BELGIUM GRANTS FOR SCIENTIFIC RESEARCH 188736 ELECTRONIC FUND/WIRE TRANSFER 0 EUROPE (INCLUDING ICELAND & GREENLAND) - ALBANIA, ANDORRA, AUSTRIA, BELGIUM GRANTS FOR SCIENTIFIC RESEARCH 140087 ELECTRONIC FUND/WIRE TRANSFER 0 EUROPE (INCLUDING ICELAND & GREENLAND) - ALBANIA, ANDORRA, AUSTRIA, BELGIUM GRANTS FOR SCIENTIFIC RESEARCH 9288 ELECTRONIC FUND/WIRE TRANSFER 0 EUROPE (INCLUDING ICELAND & GREENLAND) - ALBANIA, ANDORRA, AUSTRIA, BELGIUM GRANTS FOR SCIENTIFIC RESEARCH 98235 CHECK 0 NORTH AMERICA - CANADA AND MEXICO, BUT NOT THE UNITED STATES GRANTS FOR SCIENTIFIC RESEARCH 54497 CHECK 0 NORTH AMERICA - CANADA AND MEXICO, BUT NOT THE UNITED STATES GRANTS FOR SCIENTIFIC RESEARCH 58202 CHECK 0 SUB-SAHARAN AFRICA - ANGOLA, BENIN, BOTSWANA, BURKINA FASO, GRANTS FOR SCIENTIFIC RESEARCH 86886 CHECK 0 SUB-SAHARAN AFRICA - ANGOLA, BENIN, BOTSWANA, BURKINA FASO, GRANTS FOR SCIENTIFIC RESEARCH 138881 ELECTRONIC FUND/WIRE TRANSFER 0 SUB-SAHARAN AFRICA - ANGOLA, BENIN, BOTSWANA, BURKINA FASO, GRANTS FOR SCIENTIFIC RESEARCH 71901 ELECTRONIC FUND/WIRE TRANSFER 0 SUB-SAHARAN AFRICA - ANGOLA, BENIN, BOTSWANA, BURKINA FASO, GRANTS FOR SCIENTIFIC RESEARCH 232761 ELECTRONIC FUND/WIRE TRANSFER 0 SUB-SAHARAN AFRICA - ANGOLA, BENIN, BOTSWANA, BURKINA FASO, GRANTS FOR SCIENTIFIC RESEARCH 53455 ELECTRONIC FUND/WIRE TRANSFER 0 13 0 1 0 1 0 1 0 PART I, LINE 2: TSRI MONITORS THE AMOUNTS PROVIDED TO THE FOREIGN ORGANIZATION BY ADHERENCE TO A GRANT CONTRACT AND MONITORS DETAILED BILLING STATEMENTS OF RESEARCH EXPENDITURES. PART III ACCOUNTING METHOD: SCHEDULE F, PART IV: TSRI HAS LESS THAN 10% OWNERSHIP IN A FOREIGN CORPORATION DURING THE TAX YEAR, AND THEREFORE, WAS NOT REQUIRED TO FILE FORM 5471. 1 ACTIVE MINDS INC 2001 S STREET NW SUITE 630 WASHINGTON DC 20009 200587172 501(C)(3) 204390 GRANTS FOR SCIENTIFIC RESEARCH AMERICAN COLLEGE HEALTH ASSOCIATION 1362 MELLON RD SUITE 180 HANOVER MD 21076 362681352 501(C)(3) 176755 GRANTS FOR SCIENTIFIC RESEARCH BAYLOR COLLEGE OF MEDICINE ONE BAYLOR PLAZA MS BCM160 HOUSTON TX 77030 741613878 501(C)(3) 128425 GRANTS FOR SCIENTIFIC RESEARCH BLOODWORKS NORTHWEST 921 TERRY AVE SEATTLE WA 98104 911019655 501(C)(3) 76901 GRANTS FOR SCIENTIFIC RESEARCH BLUE CROSS BLUE SHIELD 225 N MICHIGAN AVE CHICAGO IL 60601 135656874 501(C)(4) 1261110 GRANTS FOR SCIENTIFIC RESEARCH BOSTON MEDICAL CENTER CORPORATION 1 BOSTON MEDICAL CENTER PLACE BOSTON MA 02118 043314093 501(C)(3) 74354 GRANTS FOR SCIENTIFIC RESEARCH BOSTON UNIVERSITY ONE SILBER WAY BOSTON MA 02215 042103547 501(C)(3) 47239 GRANTS FOR SCIENTIFIC RESEARCH BRIGHAM YOUNG UNIVERSITY A-153 ASB PROVO UT 84602 870217280 501(C)(3) 163055 GRANTS FOR SCIENTIFIC RESEARCH BROAD INSTITUTE 415 MAIN ST CAMBRIDGE MA 02142 263428781 501(C)(3) 451905 GRANTS FOR SCIENTIFIC RESEARCH CAREEVOLUTION 625 N MAIN ST ANN ARBOR MI 48104 731677920 7066593 GRANTS FOR SCIENTIFIC RESEARCH CASE WESTERN RESERVE UNIVERSITY 10900 EUCLID AVENUE CLEVELAND OH 44106 341018992 501(C)(3) 58431 GRANTS FOR SCIENTIFIC RESEARCH CESSATION THERAPEUTICS 3031 TISCH WAY STE 505 SAN JOSE CA 95128 823906297 88910 GRANTS FOR SCIENTIFIC RESEARCH COLUMBIA UNIVERISITY 622 WEST 113TH STREET MAIL CODE 4524 NEW YORK NY 10025 135598093 501(C)(3) 459615 GRANTS FOR SCIENTIFIC RESEARCH DANA FARBER FOUNDATION 450 BROOKLINE AVE STE BP418 BOSTON MA 02215 043102433 501(C)(3) 41772 GRANTS FOR SCIENTIFIC RESEARCH DEDALUS HEALTHCARE SYSTEMS GROUP 3411 SILVERSIDE ROAD WILMINGTON DE 19810 952043126 5631729 GRANTS FOR SCIENTIFIC RESEARCH DELUGE BIOTECHNOLOGIES 6671 W 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20910 521166660 918752 GRANTS FOR SCIENTIFIC RESEARCH VANDERBILT UNIVERSITY MEDICAL CENTER 3322 WEST END AVENUE SUITE 900 NASHVILLE TN 37203 352528741 501(C)(3) 21230 GRANTS FOR SCIENTIFIC RESEARCH VETERANS MEDICAL RESEARCH FOUNDATION 3350 LA JOLLA VILLAGE DR 151A SAN DIEGO CA 92161 330189397 501(C)(3) 250617 GRANTS FOR SCIENTIFIC RESEARCH WALGREENS 108 WILMOT ROAD DEERFIELD IL 60015 471758322 1025999 GRANTS FOR SCIENTIFIC RESEARCH WEB MD 395 HUDSON STREET NEW YORK NY 10014 202783228 2385000 GRANTS FOR SCIENTIFIC RESEARCH YALE UNIVERSITY PO BOX 2038 NEW HAVEN CT 06521 060646973 501(C)(3) 108035 GRANTS FOR SCIENTIFIC RESEARCH 76 15 SCHOLARSHIPS & STIPENDS, TSRI GRADUATE SCHOOL 403 14029323 0 PART I, LINE 2: TSRI MONITORS THE AMOUNTS PROVIDED TO THE DOMESTIC ORGANIZATION BY ADHERENCE TO A GRANT CONTRACT AND MONITORS DETAILED BILLING STATEMENTS OF RESEARCH EXPENDITURES. GRADUATE STUDENT STIPENDS ARE PROCESSED VIA PERSONNEL ACTION FORMS WHICH ARE APPROVED BY THE GRADUATE OFFICE AND HUMAN RESOURCES PRIOR TO BEING SENT TO THE PAYROLL OFFICE. ONCE APPROVED, GRADUATE STUDENTS ARE SET UP IN TSRI'S PAYROLL SYSTEM AND ARE DISPERSED ON THE 1ST AND 15TH OF EACH MONTH. MONITORING IS DONE VIA THE INTERACTION BETWEEN THE STUDENT AND FACULTY ADVISOR. AS LONG AS THE STUDENT IS PROGRESSING, SHE/HE WOULD CONTINUE TO BE PAID. X 1 1 X X X X 0 0 0 0 0 0 0 0 0 ERIC TOPOL PROFESSOR/EXEC VP 1057873 0 0 0 0 0 56999 0 13339 0 1128211 0 0 0 PETER G SCHULTZ PRESIDENT/CEO 847448 0 62907 0 26424 0 57000 0 15139 0 1008918 0 0 0 MATTHEW S TREMBLAY CHIEF OPERATING OFFICER 533734 0 85001 0 1139 0 57000 0 17755 0 694629 0 0 0 JAMES R WILLIAMSON VP RSCH & ACADEMIC AFFAIRS 394634 0 24960 0 7084 0 57000 0 14920 0 498598 0 0 0 VADIM KLYUSHNICHENKO VP PHARMACEUTICAL DEV & QUAL 333295 0 61806 0 1929 0 43857 0 48419 0 489306 0 0 0 PAMELA GARZONE CHIEF MEDICAL OFFICER 351241 0 27376 0 25977 0 47733 0 16057 0 468384 0 0 0 JEFFREY KELLY DIRECTOR/PROFESSOR (END 09/21) 355161 0 0 0 24232 0 57000 0 14406 0 450799 0 0 0 JENNIFER CROSBY VP PHILANTHROPY 350562 0 16997 0 1709 0 57000 0 16553 0 442821 0 0 0 JARED M MACHADO TREASURER (END 10/20)/CAO 345843 0 18025 0 1125 0 57000 0 19429 0 441422 0 0 0 KARL SHARPLESS PROFESSOR 356311 0 0 0 8750 0 57000 0 14030 0 436091 0 0 0 ALICE T FENG TREASURER (START 10/20)/CFO 308690 0 28950 0 20306 0 52434 0 18232 0 428612 0 0 0 DOUGLAS A BINGHAM EVP SCRIPPS FL 299581 0 10192 0 0 0 57000 0 13003 0 379776 0 0 0 DEMETRIOS I ANDRIKOS SEC/VP LEGAL/GEN COUNSEL (END 01/21) 288755 0 7150 0 3281 0 57000 0 16451 0 372637 0 0 0 KELLY SAN GEORGE CFO VP ADM. CALIBR 224528 0 21842 0 2744 0 34549 0 15979 0 299642 0 0 0 MARY WANG ASSISTANT SECRETARY 156140 0 19201 0 0 0 15694 0 11500 0 202535 0 0 0 ALANNA RUTAN SEC./CHIEF COMP. OFF. (START 02/21) 127453 0 18703 0 0 0 12830 0 10300 0 169286 0 0 0 PART I, LINE 1A BUSINESS TRAVEL AND FIRST CLASS TRAVEL. THE SCRIPPS RESEARCH INSTITUTE ALLOWS FOR BUSINESS TRAVEL FOR CERTAIN KEY EMPLOYEES FOR LONG HAUL FLIGHTS. IN CERTAIN CIRCUMSTANCES, BUSINESS CLASS IS NOT AVAILABLE ON SMALLER AIRCRAFT. IN THOSE CIRCUMSTANCES, TSRI ALLOWS FIRST CLASS TRAVEL. OTHER INFORMATION RELATED TO FORM 990, PART VII, LINE 5: ERIC TOPOL, M.D., RECEIVED COMPENSATION FROM AN UNRELATED ORGANIZATION, SCRIPPS CLINIC MEDICAL GROUP, FOR SERVICES PROVIDED TO THE SCRIPPS RESEARCH INSTITUTE. IN 2020, IN EXCHANGE FOR THESE SERVICES, THE SCRIPPS RESEARCH INSTITUTE REIMBURSED THE SCRIPPS MEDICAL GROUP $750,000 A CALIFORNIA INFRASTRUCTURE & ECONOMIC DEVELOPMENT BANK 630304653 13034AMU1 2016-08-30 40511601 SEE PART VI 0 0 0 A 11600000 40511601 3116794 648704 37181484 2016 1 1 1 1 A 0 0 0 1 0 0.00000 0.00000 0.00000 0 0 1 A 0 0 0 1 0 0 0 0 1 A 1 DATE REBATE COMPUTATION PERFORMED ISSUER NAME: CALIFORNIA INFRASTRUCTURE & ECONOMIC DEVELOPMENT BANK DATE THE REBATE COMPUTATION WAS PERFORMED: 06/29/2022 SCHEDULE K, PART I, BOND ISSUES: (A) ISSUE NAME: CALIFORNIA INFRASTRUCTURE & ECONOMIC DEVELOPMENT BANK (F) DESCRIPTION ON PURPOSE: REFUND AND DEFEASE BONDS PREVIOUSLY ISSUED FOR THE BENEFIT OF THE INSTITUTE ON 06/29/2000 AND 02/23/2005. SCHEDULE K, PART III, LINE 3D: OVERALL PRIVATE USE ISN'T MATERIAL AND OUTSIDE COUNSEL WOULD REVIEW ANY SIGNIFICANT AGREEMENTS. SCHEDULE K, PART IV, LINE 6: THIS QUESTION IS BEING ANSWERED WITHOUT REGARD TO A YIELD-RESTRICTED ADVANCE REFUNDING ESCROW FINANCED WITH PROCEEDS OF THE BONDS. X 5 2088733 COST OR SELLING PRICE 0 0 1 0 PART I, COLUMN (B): NUMBER OF CONTRIBUTIONS OF PUBLICLY TRADED STOCK. FORM 990, PART VI, SECTION B, LINE 11B ON JUNE 30, 2022, THE AUDIT COMMITTEE REVIEWED A DRAFT OF THE FORM 990 (INCLUDING ALL SUPPLEMENTAL SCHEDULES). THIS REVIEW INCLUDED A PRESENTATION OF THE STATEMENTS BY THE CHIEF FINANCIAL OFFICER WITH PARTICULAR EMPHASIS ON DISCLOSURES ABOUT GOVERNANCE AND ABOUT TRANSACTIONS WITH INTERESTED PERSONS. THE 990 WILL BE PROVIDED TO THE FULL BOARD OF DIRECTORS PRIOR TO FILING. FORM 990, PART VI, SECTION B, LINE 12C TSRI'S CONFLICT OF INTEREST POLICIES AND PROCEDURES APPLY TO MEMBERS OF THE BOARD OF DIRECTORS, OFFICERS, KEY PERSONNEL, AND THEIR FAMILY MEMBERS (ALTOGETHER COVERED INDIVIDUALS) TO PROTECT THE INTERESTS OF TSRI WHEN IT IS CONTEMPLATING ENTERING INTO A TRANSACTION OR ARRANGEMENT THAT COULD: 1) BENEFIT THE PRIVATE INTEREST OF A COVERED INDIVIDUAL WITHIN THE MEANING OF TREASURY REGULATION SECTION 1.501(C)(3)-1(D)(1)(II), 2) RESULT IN A POSSIBLE EXCESS BENEFIT TRANSACTION WITHIN THE MEANING OF SECTION 4958(C) OF THE INTERNAL REVENUE CODE OF 1986, AS AMENDED; OR 3) BE A SELF-DEALING TRANSACTION WITHIN THE MEANING OF SECTION 5233 OF THE CALIFORNIA CORPORATIONS CODE (THE "CORPORATIONS CODE"). TSRI'S POLICIES AND PROCEDURES ARE INTENDED TO SUPPLEMENT, BUT NOT REPLACE, ANY STATE AND FEDERAL LAWS GOVERNING ACTUAL, POTENTIAL, OR APPARENT CONFLICT OF INTEREST APPLICABLE TO TSRI. DISCLOSURE DOCUMENTS RESPONSIVE TO TSRI'S POLICIES ARE ANNUALLY SUBMITTED BY COVERED INDIVIDUALS, AND ARE REVIEWED BY TSRI ADMINISTRATION FOR PERTINENT RELATIONSHIPS. ANY TRANSACTIONS OR ARRANGEMENTS INVOLVING COVERED INDIVIDUALS THAT FALL WITHIN THE SCOPE OF THE POLICIES ARE THEN SUBJECT TO REVIEW AND CONSIDERATION BY NON-CONFLICTED BOARD OF DIRECTOR MEMBERS, WITH CONFLICTED MEMBERS BEING RECUSED FROM ANY DEBATE AND VOTE TO APPROVE OR DISAPPROVE. FORM 990, PART VI, SECTION B, LINE 15 THE COMPENSATION OF THE CEO AND CERTAIN OTHER KEY EXECUTIVES WAS REVIEWED AND APPROVED BY THE BOARD OF DIRECTORS. THIS REVIEW WAS BASED, IN PART, ON ANALYSIS PERFORMED BY THE HUMAN RESOURCES DEPARTMENT, AND INCLUDED DATA FROM OUTSIDE CONSULTANTS OR INTERNALLY-CONDUCTED RESEARCH. ON AN ONGOING BASIS, EXECUTIVES MAY PARTICIPATE IN THE NORMAL ANNUAL SALARY INCREASE PROGRAM, WHICH IS BASED ON A RECOMMENDATION FROM THE HUMAN RESOURCES DEPARTMENT BASED ON MARKET RESEARCH. ANY UNUSUAL OR POTENTIALLY NON-QUALIFIED COMPENSATION WOULD BE REVIEWED BY OUTSIDE COUNSEL FOR ANY TAX COMPLIANCE ISSUES. FORM 990, PART VI, SECTION C, LINE 19 GOVERNING DOCUMENTS AND CONFLICT OF INTEREST POLICIES ARE NOT AVAILABLE TO THE PUBLIC AT THIS TIME. THE FINANCIAL STATEMENTS ARE PROVIDED TO BOND HOLDERS THROUGH TSRI'S DISSEMINATION AGENT. THE ANNUAL INFORMATION RETURN IS PROVIDED UPON REQUEST. FORM 990, PART IX, LINE 11G PURCHASES SERVICE AND MAINTENANCE: PROGRAM SERVICE EXPENSES 47,288,944. MANAGEMENT AND GENERAL EXPENSES 1,938,727. FUNDRAISING EXPENSES 593,699. TOTAL EXPENSES 49,821,370. FORM 990, PART XI, LINE 9: NET ASSET RELEASED 0. ROUNDING -147. 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