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            <BusinessNameLine1Txt>GARDINER LIBRARY</BusinessNameLine1Txt>
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      <InvestmentsCorporateStockGrp>
        <StockNm>CLEARSIDE BIOMEDICAL INC</StockNm>
        <EOYBookValueAmt>14190</EOYBookValueAmt>
        <EOYFMVAmt>6182</EOYFMVAmt>
      </InvestmentsCorporateStockGrp>
      <InvestmentsCorporateStockGrp>
        <StockNm>COGENT INC</StockNm>
        <EOYBookValueAmt>15509</EOYBookValueAmt>
        <EOYFMVAmt>21021</EOYFMVAmt>
      </InvestmentsCorporateStockGrp>
      <InvestmentsCorporateStockGrp>
        <StockNm>COHU INC</StockNm>
        <EOYBookValueAmt>249300</EOYBookValueAmt>
        <EOYFMVAmt>300911</EOYFMVAmt>
      </InvestmentsCorporateStockGrp>
      <InvestmentsCorporateStockGrp>
        <StockNm>DIAMEDICA THERAPEUTICS INC</StockNm>
        <EOYBookValueAmt>363553</EOYBookValueAmt>
        <EOYFMVAmt>249365</EOYFMVAmt>
      </InvestmentsCorporateStockGrp>
      <InvestmentsCorporateStockGrp>
        <StockNm>DIAMEDICA THERAPEUTICS INC - C</StockNm>
        <EOYBookValueAmt>1509200</EOYBookValueAmt>
        <EOYFMVAmt>1436050</EOYFMVAmt>
      </InvestmentsCorporateStockGrp>
      <InvestmentsCorporateStockGrp>
        <StockNm>ELEDON PHARMACEUTICALS ORD SHS</StockNm>
        <EOYBookValueAmt>68015</EOYBookValueAmt>
        <EOYFMVAmt>70560</EOYFMVAmt>
      </InvestmentsCorporateStockGrp>
      <InvestmentsCorporateStockGrp>
        <StockNm>EMCORE CORPORATION</StockNm>
        <EOYBookValueAmt>187459</EOYBookValueAmt>
        <EOYFMVAmt>186534</EOYFMVAmt>
      </InvestmentsCorporateStockGrp>
      <InvestmentsCorporateStockGrp>
        <StockNm>EVAXION BIOTECH ADR</StockNm>
        <EOYBookValueAmt>24839</EOYBookValueAmt>
        <EOYFMVAmt>22100</EOYFMVAmt>
      </InvestmentsCorporateStockGrp>
      <InvestmentsCorporateStockGrp>
        <StockNm>F-STAR THERAPEUTICS INC</StockNm>
        <EOYBookValueAmt>22203</EOYBookValueAmt>
        <EOYFMVAmt>21034</EOYFMVAmt>
      </InvestmentsCorporateStockGrp>
      <InvestmentsCorporateStockGrp>
        <StockNm>FENNEC PHARMACEUTICALS INC</StockNm>
        <EOYBookValueAmt>34</EOYBookValueAmt>
        <EOYFMVAmt>22</EOYFMVAmt>
      </InvestmentsCorporateStockGrp>
      <InvestmentsCorporateStockGrp>
        <StockNm>GAIN THERAPEUTICS ORD SHS</StockNm>
        <EOYBookValueAmt>749999</EOYBookValueAmt>
        <EOYFMVAmt>1207741</EOYFMVAmt>
      </InvestmentsCorporateStockGrp>
      <InvestmentsCorporateStockGrp>
        <StockNm>GIGA-TRONICS INC - WARRANT</StockNm>
        <EOYBookValueAmt>749999</EOYBookValueAmt>
        <EOYFMVAmt>810175</EOYFMVAmt>
      </InvestmentsCorporateStockGrp>
      <InvestmentsCorporateStockGrp>
        <StockNm>HTG MOLECULAR DIAGNOSTICS CNV</StockNm>
        <EOYBookValueAmt>400020</EOYBookValueAmt>
        <EOYFMVAmt>244984</EOYFMVAmt>
      </InvestmentsCorporateStockGrp>
      <InvestmentsCorporateStockGrp>
        <StockNm>HTG MOLECULAR DIAGNOSTICS INC</StockNm>
        <EOYBookValueAmt>207953</EOYBookValueAmt>
        <EOYFMVAmt>263911</EOYFMVAmt>
      </InvestmentsCorporateStockGrp>
      <InvestmentsCorporateStockGrp>
        <StockNm>ICAD INC.</StockNm>
        <EOYBookValueAmt>26863</EOYBookValueAmt>
        <EOYFMVAmt>18000</EOYFMVAmt>
      </InvestmentsCorporateStockGrp>
      <InvestmentsCorporateStockGrp>
        <StockNm>IDEAL POWER ORD SHS</StockNm>
        <EOYBookValueAmt>178875</EOYBookValueAmt>
        <EOYFMVAmt>150750</EOYFMVAmt>
      </InvestmentsCorporateStockGrp>
      <InvestmentsCorporateStockGrp>
        <StockNm>LAKELAND INDUSTRIES, INC.</StockNm>
        <EOYBookValueAmt>45510</EOYBookValueAmt>
        <EOYFMVAmt>52471</EOYFMVAmt>
      </InvestmentsCorporateStockGrp>
      <InvestmentsCorporateStockGrp>
        <StockNm>LIFE TECHNOLOGIES CORP</StockNm>
        <EOYBookValueAmt>979256</EOYBookValueAmt>
        <EOYFMVAmt>918392</EOYFMVAmt>
      </InvestmentsCorporateStockGrp>
      <InvestmentsCorporateStockGrp>
        <StockNm>LIQTECH INTERNATIONAL INC</StockNm>
        <EOYBookValueAmt>2101051</EOYBookValueAmt>
        <EOYFMVAmt>2280804</EOYFMVAmt>
      </InvestmentsCorporateStockGrp>
      <InvestmentsCorporateStockGrp>
        <StockNm>MEDIWOUND</StockNm>
        <EOYBookValueAmt>12434</EOYBookValueAmt>
        <EOYFMVAmt>7297</EOYFMVAmt>
      </InvestmentsCorporateStockGrp>
      <InvestmentsCorporateStockGrp>
        <StockNm>MEI PHARMA INC</StockNm>
        <EOYBookValueAmt>195000</EOYBookValueAmt>
        <EOYFMVAmt>200250</EOYFMVAmt>
      </InvestmentsCorporateStockGrp>
      <InvestmentsCorporateStockGrp>
        <StockNm>MIROMATRIX MED INC</StockNm>
        <EOYBookValueAmt>2024279</EOYBookValueAmt>
        <EOYFMVAmt>1054875</EOYFMVAmt>
      </InvestmentsCorporateStockGrp>
      <InvestmentsCorporateStockGrp>
        <StockNm>MOLECULAR TEMPLATES INC</StockNm>
        <EOYBookValueAmt>1740645</EOYBookValueAmt>
        <EOYFMVAmt>611465</EOYFMVAmt>
      </InvestmentsCorporateStockGrp>
      <InvestmentsCorporateStockGrp>
        <StockNm>NUVVE HOLDING CORP WARRANTS</StockNm>
      </InvestmentsCorporateStockGrp>
      <InvestmentsCorporateStockGrp>
        <StockNm>NUVVE HOLDING ORD SHS</StockNm>
        <EOYBookValueAmt>343790</EOYBookValueAmt>
        <EOYFMVAmt>406566</EOYFMVAmt>
      </InvestmentsCorporateStockGrp>
      <InvestmentsCorporateStockGrp>
        <StockNm>OMNIQ CORP COMMON</StockNm>
        <EOYBookValueAmt>788914</EOYBookValueAmt>
        <EOYFMVAmt>653108</EOYFMVAmt>
      </InvestmentsCorporateStockGrp>
      <InvestmentsCorporateStockGrp>
        <StockNm>ORYZON GENOMICS</StockNm>
        <EOYBookValueAmt>97840</EOYBookValueAmt>
        <EOYFMVAmt>99656</EOYFMVAmt>
      </InvestmentsCorporateStockGrp>
      <InvestmentsCorporateStockGrp>
        <StockNm>PERFORMANT FINANCIAL</StockNm>
        <EOYBookValueAmt>147336</EOYBookValueAmt>
        <EOYFMVAmt>91098</EOYFMVAmt>
      </InvestmentsCorporateStockGrp>
      <InvestmentsCorporateStockGrp>
        <StockNm>PLUG POWER INC</StockNm>
        <EOYBookValueAmt>1465</EOYBookValueAmt>
        <EOYFMVAmt>14115</EOYFMVAmt>
      </InvestmentsCorporateStockGrp>
      <InvestmentsCorporateStockGrp>
        <StockNm>QUICKLOGIC</StockNm>
        <EOYBookValueAmt>47583</EOYBookValueAmt>
        <EOYFMVAmt>48954</EOYFMVAmt>
      </InvestmentsCorporateStockGrp>
      <InvestmentsCorporateStockGrp>
        <StockNm>RECRO PHARMA INC</StockNm>
        <EOYBookValueAmt>30758</EOYBookValueAmt>
        <EOYFMVAmt>24908</EOYFMVAmt>
      </InvestmentsCorporateStockGrp>
      <InvestmentsCorporateStockGrp>
        <StockNm>RELMADA THERAPEUTICS</StockNm>
        <EOYBookValueAmt>9862</EOYBookValueAmt>
        <EOYFMVAmt>11265</EOYFMVAmt>
      </InvestmentsCorporateStockGrp>
      <InvestmentsCorporateStockGrp>
        <StockNm>RENEO PHARMACEUTICALS ORD SHS</StockNm>
        <EOYBookValueAmt>42757</EOYBookValueAmt>
        <EOYFMVAmt>58422</EOYFMVAmt>
      </InvestmentsCorporateStockGrp>
      <InvestmentsCorporateStockGrp>
        <StockNm>REPRO MEDSYSTEMS INC</StockNm>
        <EOYBookValueAmt>85818</EOYBookValueAmt>
        <EOYFMVAmt>87288</EOYFMVAmt>
      </InvestmentsCorporateStockGrp>
      <InvestmentsCorporateStockGrp>
        <StockNm>RESTORBIO RTS</StockNm>
      </InvestmentsCorporateStockGrp>
      <InvestmentsCorporateStockGrp>
        <StockNm>RIMINI STR INC</StockNm>
        <EOYBookValueAmt>6276</EOYBookValueAmt>
        <EOYFMVAmt>5570</EOYFMVAmt>
      </InvestmentsCorporateStockGrp>
      <InvestmentsCorporateStockGrp>
        <StockNm>SCIENTIFIC INDUSTRIES</StockNm>
        <EOYBookValueAmt>19114</EOYBookValueAmt>
        <EOYFMVAmt>22800</EOYFMVAmt>
      </InvestmentsCorporateStockGrp>
      <InvestmentsCorporateStockGrp>
        <StockNm>SCIENTIFIC INDUSTRIES, INC - C</StockNm>
        <EOYBookValueAmt>907526</EOYBookValueAmt>
        <EOYFMVAmt>917078</EOYFMVAmt>
      </InvestmentsCorporateStockGrp>
      <InvestmentsCorporateStockGrp>
        <StockNm>SCIENTIFIC INDUSTRIES, INC - W</StockNm>
        <EOYFMVAmt>114634</EOYFMVAmt>
      </InvestmentsCorporateStockGrp>
      <InvestmentsCorporateStockGrp>
        <StockNm>SEELOS THERAPEUTICS INC</StockNm>
        <EOYBookValueAmt>16200</EOYBookValueAmt>
        <EOYFMVAmt>16300</EOYFMVAmt>
      </InvestmentsCorporateStockGrp>
      <InvestmentsCorporateStockGrp>
        <StockNm>SPECTRA7 MICROSYSTEMS INC</StockNm>
        <EOYBookValueAmt>2006400</EOYBookValueAmt>
        <EOYFMVAmt>3579922</EOYFMVAmt>
      </InvestmentsCorporateStockGrp>
      <InvestmentsCorporateStockGrp>
        <StockNm>UROGEN PHARMA LTD</StockNm>
        <EOYBookValueAmt>247135</EOYBookValueAmt>
        <EOYFMVAmt>203628</EOYFMVAmt>
      </InvestmentsCorporateStockGrp>
      <InvestmentsCorporateStockGrp>
        <StockNm>VALLON PHARMACEUTICALS INC</StockNm>
        <EOYBookValueAmt>27411</EOYBookValueAmt>
        <EOYFMVAmt>28088</EOYFMVAmt>
      </InvestmentsCorporateStockGrp>
      <InvestmentsCorporateStockGrp>
        <StockNm>VASCULAR BIOGENICS LTD</StockNm>
        <EOYBookValueAmt>10690</EOYBookValueAmt>
        <EOYFMVAmt>8774</EOYFMVAmt>
      </InvestmentsCorporateStockGrp>
      <InvestmentsCorporateStockGrp>
        <StockNm>VERTTEX ENERGY, INC</StockNm>
        <EOYBookValueAmt>4055919</EOYBookValueAmt>
        <EOYFMVAmt>2659521</EOYFMVAmt>
      </InvestmentsCorporateStockGrp>
      <InvestmentsCorporateStockGrp>
        <StockNm>VIRACTA THERAPEUTICS</StockNm>
        <EOYBookValueAmt>46779</EOYBookValueAmt>
        <EOYFMVAmt>28061</EOYFMVAmt>
      </InvestmentsCorporateStockGrp>
      <InvestmentsCorporateStockGrp>
        <StockNm>WESTPORT INNOVATIONS INC</StockNm>
        <EOYBookValueAmt>17216</EOYBookValueAmt>
        <EOYFMVAmt>16590</EOYFMVAmt>
      </InvestmentsCorporateStockGrp>
      <InvestmentsCorporateStockGrp>
        <StockNm>X4 PHARMACEUTICALS</StockNm>
        <EOYBookValueAmt>2364393</EOYBookValueAmt>
        <EOYFMVAmt>646238</EOYFMVAmt>
      </InvestmentsCorporateStockGrp>
    </InvestmentsCorpStockSchedule>
    <InvestmentsOtherSchedule2 documentId="InvOtherSch2">
      <InvestmentsOtherGrp>
        <CategoryOrItemTxt>LIFESCI VENTURE SPV XIII LLC</CategoryOrItemTxt>
        <BookValueAmt>606663</BookValueAmt>
        <EOYFMVAmt>606662</EOYFMVAmt>
      </InvestmentsOtherGrp>
      <InvestmentsOtherGrp>
        <CategoryOrItemTxt>LIQTECH INTL INC - (PRE-FUNDED</CategoryOrItemTxt>
        <BookValueAmt>2969300</BookValueAmt>
        <EOYFMVAmt>3382500</EOYFMVAmt>
      </InvestmentsOtherGrp>
      <InvestmentsOtherGrp>
        <CategoryOrItemTxt>MAXONA PHARMACEUTICALS, INC. P</CategoryOrItemTxt>
        <BookValueAmt>1000000</BookValueAmt>
        <EOYFMVAmt>800000</EOYFMVAmt>
      </InvestmentsOtherGrp>
      <InvestmentsOtherGrp>
        <CategoryOrItemTxt>OMEGA THERAPEUTICS, INC PFD SE</CategoryOrItemTxt>
        <BookValueAmt>999999</BookValueAmt>
        <EOYFMVAmt>800000</EOYFMVAmt>
      </InvestmentsOtherGrp>
    </InvestmentsOtherSchedule2>
    <OtherExpensesSchedule documentId="OtherExpensesSch">
      <OtherExpensesScheduleGrp>
        <Desc>Administrative Fees</Desc>
        <RevenueAndExpensesPerBooksAmt>136749</RevenueAndExpensesPerBooksAmt>
        <DisbursementsCharitablePrpsAmt>136749</DisbursementsCharitablePrpsAmt>
      </OtherExpensesScheduleGrp>
      <OtherExpensesScheduleGrp>
        <Desc>Bank Charges</Desc>
        <RevenueAndExpensesPerBooksAmt>1477</RevenueAndExpensesPerBooksAmt>
        <NetInvestmentIncomeAmt>1477</NetInvestmentIncomeAmt>
      </OtherExpensesScheduleGrp>
      <OtherExpensesScheduleGrp>
        <Desc>K-1 Exp LIFESCI VENTURE SPV XI</Desc>
        <RevenueAndExpensesPerBooksAmt>5337</RevenueAndExpensesPerBooksAmt>
        <NetInvestmentIncomeAmt>5337</NetInvestmentIncomeAmt>
      </OtherExpensesScheduleGrp>
      <OtherExpensesScheduleGrp>
        <Desc>State or Local Filing Fees</Desc>
        <RevenueAndExpensesPerBooksAmt>25</RevenueAndExpensesPerBooksAmt>
        <DisbursementsCharitablePrpsAmt>25</DisbursementsCharitablePrpsAmt>
      </OtherExpensesScheduleGrp>
    </OtherExpensesSchedule>
    <OtherIncomeSchedule2 documentId="OtherIncomeSch2">
      <OtherIncomeDetail>
        <Desc>Federal Tax Refund</Desc>
        <RevenueAndExpensesPerBooksAmt>690</RevenueAndExpensesPerBooksAmt>
      </OtherIncomeDetail>
      <OtherIncomeDetail>
        <Desc>Foreign Currency Loss</Desc>
        <RevenueAndExpensesPerBooksAmt>-10194</RevenueAndExpensesPerBooksAmt>
        <NetInvestmentIncomeAmt>-10194</NetInvestmentIncomeAmt>
      </OtherIncomeDetail>
      <OtherIncomeDetail>
        <Desc>Interest Income from Notes</Desc>
        <RevenueAndExpensesPerBooksAmt>57500</RevenueAndExpensesPerBooksAmt>
        <NetInvestmentIncomeAmt>57500</NetInvestmentIncomeAmt>
      </OtherIncomeDetail>
    </OtherIncomeSchedule2>
    <OtherNotesLoansRcvblLongSch documentId="OthNoteLoanRcvblLong">
      <OtherNotesLoansRcvblLongGrp>
        <BorrowerNameGrp>
          <BusinessName>
            <BusinessNameLine1Txt>CYREN LTD</BusinessNameLine1Txt>
          </BusinessName>
        </BorrowerNameGrp>
        <LoanOriginalAmt>1000000</LoanOriginalAmt>
        <BalanceDueAmt>1000000</BalanceDueAmt>
        <NoteDt>2020-03</NoteDt>
        <LoanMaturityDt>2024-03</LoanMaturityDt>
        <RepaymentTermsTxt>INT/PRIN DUE SEMI-ANNU&amp;ON MATURITY</RepaymentTermsTxt>
        <InterestRt>5.75</InterestRt>
        <SecurityProvidedBorrowerTxt>NONE</SecurityProvidedBorrowerTxt>
        <LoanPurposeTxt>INVESTMENT</LoanPurposeTxt>
        <LenderConsiderationDesc>CASH CASH CASH</LenderConsiderationDesc>
        <ConsiderationFMVAmt>1000000</ConsiderationFMVAmt>
      </OtherNotesLoansRcvblLongGrp>
      <OtherNotesLoansRcvblLongGrp>
        <BorrowerNameGrp>
          <BusinessName>
            <BusinessNameLine1Txt>CIRCULOGENE THERANOSTICS INC</BusinessNameLine1Txt>
          </BusinessName>
        </BorrowerNameGrp>
        <LoanOriginalAmt>1000000</LoanOriginalAmt>
        <BalanceDueAmt>1000000</BalanceDueAmt>
        <NoteDt>2021-03</NoteDt>
        <LoanMaturityDt>2025-04</LoanMaturityDt>
        <RepaymentTermsTxt>INT&amp;PRIN DUE ANNUALLY&amp;ON MATURITY</RepaymentTermsTxt>
        <InterestRt>5.</InterestRt>
        <SecurityProvidedBorrowerTxt>NONE</SecurityProvidedBorrowerTxt>
        <LoanPurposeTxt>INVESTMENT</LoanPurposeTxt>
        <LenderConsiderationDesc>CASH CASH CASH</LenderConsiderationDesc>
        <ConsiderationFMVAmt>1000000</ConsiderationFMVAmt>
      </OtherNotesLoansRcvblLongGrp>
      <OtherNotesLoansRcvblLongGrp>
        <BorrowerNameGrp>
          <BusinessName>
            <BusinessNameLine1Txt>FRESHREALM LLC</BusinessNameLine1Txt>
          </BusinessName>
        </BorrowerNameGrp>
        <LoanOriginalAmt>2000000</LoanOriginalAmt>
        <BalanceDueAmt>2000000</BalanceDueAmt>
        <NoteDt>2021-07</NoteDt>
        <LoanMaturityDt>2022-07</LoanMaturityDt>
        <RepaymentTermsTxt>INTEREST AND PRINCIPAL ON MATURITY</RepaymentTermsTxt>
        <InterestRt>8.</InterestRt>
        <SecurityProvidedBorrowerTxt>ALL ASSETS OF THE COMPANY</SecurityProvidedBorrowerTxt>
        <LoanPurposeTxt>INVESTMENT</LoanPurposeTxt>
        <LenderConsiderationDesc>CASH CASH CASH</LenderConsiderationDesc>
        <ConsiderationFMVAmt>2000000</ConsiderationFMVAmt>
      </OtherNotesLoansRcvblLongGrp>
    </OtherNotesLoansRcvblLongSch>
    <OtherProfessionalFeesSchedule documentId="OthProfFeesSch">
      <OtherProfessionalFeesDetail>
        <CategoryTxt>Investment Management Services</CategoryTxt>
        <Amt>6345</Amt>
        <NetInvestmentIncomeAmt>6345</NetInvestmentIncomeAmt>
      </OtherProfessionalFeesDetail>
    </OtherProfessionalFeesSchedule>
    <ReasonableCauseExplanation documentId="ReasonableCauseExpl">
      <ExplanationTxt>The Foundation's tax preparer is located in Nassau County, NY, which, per IRS release NY-2021-01 announced on September 9, 2021, is included in the list of localities that constitute a covered disaster area for purposes of Treas. Reg. Sec. 301.7508A-1(d)(2) and are entitled to tax relief due to Hurricane Ida. Additional time was needed to calculate and transmit the tax payment. Therefore, Form 2220 indicates that the Q3 or Q4 estimated tax payment made on or before the extended deadline of February 15, 2022 was, in fact, made timely on the original due date of such payment. We respectfully request that no late payment penalties be assessed in connection with such payment(s) per Treas. Reg. Sec. 301.7508A-1(c)(1).</ExplanationTxt>
    </ReasonableCauseExplanation>
    <TaxesSchedule documentId="TaxesSchedule">
      <TaxesDetail>
        <CategoryTxt>990-PF Estimated Tax for 2021</CategoryTxt>
        <Amt>202700</Amt>
      </TaxesDetail>
      <TaxesDetail>
        <CategoryTxt>990-PF Extension for 2020</CategoryTxt>
        <Amt>29120</Amt>
      </TaxesDetail>
    </TaxesSchedule>
  </ReturnData>
</Return>
