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            <BusinessNameLine1Txt>BIOCOM INSTITUTE</BusinessNameLine1Txt>
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            <AddressLine1Txt>10996 TORREYANA RD STE 200</AddressLine1Txt>
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          <GrantOrContributionPurposeTxt>Genomic Discoveries STEM Education Pilot Program</GrantOrContributionPurposeTxt>
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            <BusinessNameLine1Txt>BIOCOM INSTITUTE</BusinessNameLine1Txt>
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            <AddressLine1Txt>10996 TORREYANA RD STE 200</AddressLine1Txt>
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          <RecipientFoundationStatusTxt>PC</RecipientFoundationStatusTxt>
          <GrantOrContributionPurposeTxt>San Diego Festival of Science &amp; Engineering</GrantOrContributionPurposeTxt>
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          <RecipientBusinessName>
            <BusinessNameLine1Txt>BROAD INSTITUTE INC</BusinessNameLine1Txt>
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            <BusinessNameLine1Txt>CAL STATE EAST BAY EDUCATIONAL FOUNDATION</BusinessNameLine1Txt>
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          <RecipientBusinessName>
            <BusinessNameLine1Txt>CHARITIES AID FOUNDATION AMERICA</BusinessNameLine1Txt>
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            <BusinessNameLine1Txt>CHARITIES AID FOUNDATION AMERICA</BusinessNameLine1Txt>
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        <GrantOrContributionPdDurYrGrp>
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            <BusinessNameLine1Txt>EQUAL JUSTICE INITIATIVE</BusinessNameLine1Txt>
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            <BusinessNameLine1Txt>FUTURE KINGS INC</BusinessNameLine1Txt>
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        <GrantOrContributionPdDurYrGrp>
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            <BusinessNameLine1Txt>GENETIC ALLIANCE INC</BusinessNameLine1Txt>
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        <GrantOrContributionPdDurYrGrp>
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            <BusinessNameLine1Txt>GIVE2ASIA</BusinessNameLine1Txt>
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          <GrantOrContributionPurposeTxt>Give2Asia Disaster Campaign for Wuhan</GrantOrContributionPurposeTxt>
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        <GrantOrContributionPdDurYrGrp>
          <RecipientBusinessName>
            <BusinessNameLine1Txt>GLOBAL GENES</BusinessNameLine1Txt>
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          <GrantOrContributionPurposeTxt>Diversity in Rare Disease Diagnosis</GrantOrContributionPurposeTxt>
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        <GrantOrContributionPdDurYrGrp>
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            <BusinessNameLine1Txt>INNOCENCE PROJECT INC</BusinessNameLine1Txt>
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            <BusinessNameLine1Txt>LEUKEMIA &amp; LYMPHOMA SOCIETY INC</BusinessNameLine1Txt>
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          <GrantOrContributionPurposeTxt>TFF enduring CME/CE education initiative</GrantOrContributionPurposeTxt>
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            <BusinessNameLine1Txt>MEMORIAL SLOAN-KETTERING CANCER CENTER</BusinessNameLine1Txt>
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          <GrantOrContributionPurposeTxt>Memorial Sloan Kettering Science Enrichment Program</GrantOrContributionPurposeTxt>
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            <BusinessNameLine1Txt>NATIONAL FOUNDATION FOR THE CTRS FOR DISEASE CONTR</BusinessNameLine1Txt>
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          <GrantOrContributionPurposeTxt>Emergency Response Fund to help respond to the public health threat posed by Coronavirus</GrantOrContributionPurposeTxt>
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        <GrantOrContributionPdDurYrGrp>
          <RecipientBusinessName>
            <BusinessNameLine1Txt>NATIONAL FOUNDATION FOR THE CTRS FOR DISEASE CONTR</BusinessNameLine1Txt>
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            <AddressLine1Txt>600 PEACHTREE ST NE STE 1000</AddressLine1Txt>
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            <BusinessNameLine1Txt>NATIONAL ORGANIZATION FOR RARE DISORDERS INC</BusinessNameLine1Txt>
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            <AddressLine1Txt>55 KENOSIA AVE</AddressLine1Txt>
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            <ZIPCd>06810</ZIPCd>
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            <BusinessNameLine1Txt>PEDAL THE CAUSE - SAN DIEGO</BusinessNameLine1Txt>
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            <AddressLine1Txt>2445 5TH AVE STE 402</AddressLine1Txt>
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            <ZIPCd>92101</ZIPCd>
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        <GrantOrContributionPdDurYrGrp>
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            <BusinessNameLine1Txt>RADY CHILDRENS HOSPITAL FOUNDATION- SAN DIEGO</BusinessNameLine1Txt>
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            <AddressLine1Txt>3020 CHILDRENS WAY MC 5001</AddressLine1Txt>
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            <StateAbbreviationCd>CA</StateAbbreviationCd>
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        <GrantOrContributionPdDurYrGrp>
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            <BusinessNameLine1Txt>RANCHO SANTA FE FOUNDATION</BusinessNameLine1Txt>
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            <AddressLine1Txt>PO BOX 811</AddressLine1Txt>
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            <StateAbbreviationCd>CA</StateAbbreviationCd>
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          <RecipientFoundationStatusTxt>PC</RecipientFoundationStatusTxt>
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        <GrantOrContributionPdDurYrGrp>
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            <BusinessNameLine1Txt>REUBEN H FLEET SCIENCE CENTER</BusinessNameLine1Txt>
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            <AddressLine1Txt>1875 EL PRADO</AddressLine1Txt>
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            <StateAbbreviationCd>CA</StateAbbreviationCd>
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        <GrantOrContributionPdDurYrGrp>
          <RecipientBusinessName>
            <BusinessNameLine1Txt>SARAH MACK SCICOMM INC</BusinessNameLine1Txt>
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            <AddressLine1Txt>2433 E NORRIS ST</AddressLine1Txt>
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            <BusinessNameLine1Txt>SECOND HARVEST FOODBANK OF SOUTHERN WISCONSIN</BusinessNameLine1Txt>
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            <AddressLine1Txt>2802 DAIRY DR</AddressLine1Txt>
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        <GrantOrContributionPdDurYrGrp>
          <RecipientBusinessName>
            <BusinessNameLine1Txt>SECOND HARVEST OF SILICON VALLEY</BusinessNameLine1Txt>
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            <AddressLine1Txt>4001 N 1ST ST</AddressLine1Txt>
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        <GrantOrContributionPdDurYrGrp>
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            <BusinessNameLine1Txt>SOCIAL GOOD FUND</BusinessNameLine1Txt>
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            <AddressLine1Txt>PO BOX 5473</AddressLine1Txt>
            <CityNm>RICHMOND</CityNm>
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            <ZIPCd>94805</ZIPCd>
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        <GrantOrContributionPdDurYrGrp>
          <RecipientBusinessName>
            <BusinessNameLine1Txt>THE ALAMEDA COUNTY COMMUNITY FOOD BANK INC</BusinessNameLine1Txt>
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            <AddressLine1Txt>PO BOX 2599</AddressLine1Txt>
            <CityNm>OAKLAND</CityNm>
            <StateAbbreviationCd>CA</StateAbbreviationCd>
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        <GrantOrContributionPdDurYrGrp>
          <RecipientBusinessName>
            <BusinessNameLine1Txt>THE CLEARITY FOUNDATION</BusinessNameLine1Txt>
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            <AddressLine1Txt>434 W CEDAR ST STE 300</AddressLine1Txt>
            <CityNm>SAN DIEGO</CityNm>
            <StateAbbreviationCd>CA</StateAbbreviationCd>
            <ZIPCd>92101</ZIPCd>
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          <RecipientFoundationStatusTxt>PC</RecipientFoundationStatusTxt>
          <GrantOrContributionPurposeTxt>Treatment Decision Support Program</GrantOrContributionPurposeTxt>
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        <GrantOrContributionPdDurYrGrp>
          <RecipientBusinessName>
            <BusinessNameLine1Txt>THE ROAD HOME DANE COUNTY</BusinessNameLine1Txt>
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            <StateAbbreviationCd>WI</StateAbbreviationCd>
            <ZIPCd>53715</ZIPCd>
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          <RecipientRelationshipTxt>N/A</RecipientRelationshipTxt>
          <RecipientFoundationStatusTxt>PC</RecipientFoundationStatusTxt>
          <GrantOrContributionPurposeTxt>COVID-19 Relief Efforts</GrantOrContributionPurposeTxt>
          <Amt>10000</Amt>
        </GrantOrContributionPdDurYrGrp>
        <GrantOrContributionPdDurYrGrp>
          <RecipientBusinessName>
            <BusinessNameLine1Txt>THE SAN DIEGO FOUNDATION</BusinessNameLine1Txt>
          </RecipientBusinessName>
          <RecipientUSAddress>
            <AddressLine1Txt>2508 HISTORIC DECATUR RD STE 200</AddressLine1Txt>
            <CityNm>SAN DIEGO</CityNm>
            <StateAbbreviationCd>CA</StateAbbreviationCd>
            <ZIPCd>92106</ZIPCd>
          </RecipientUSAddress>
          <RecipientRelationshipTxt>N/A</RecipientRelationshipTxt>
          <RecipientFoundationStatusTxt>PC</RecipientFoundationStatusTxt>
          <GrantOrContributionPurposeTxt>Covid-19 Community Response Fund</GrantOrContributionPurposeTxt>
          <Amt>1000000</Amt>
        </GrantOrContributionPdDurYrGrp>
        <GrantOrContributionPdDurYrGrp>
          <RecipientBusinessName>
            <BusinessNameLine1Txt>THE UK ONLINE GIVING FOUNDATION</BusinessNameLine1Txt>
          </RecipientBusinessName>
          <RecipientForeignAddress>
            <AddressLine1Txt>6 TRULL FARM BUILDINGS</AddressLine1Txt>
            <CityNm>TRULL TETBURY</CityNm>
            <ProvinceOrStateNm>GLOUCESTERSHIRE</ProvinceOrStateNm>
            <CountryCd>UK</CountryCd>
            <ForeignPostalCd>GL8 8SQ</ForeignPostalCd>
          </RecipientForeignAddress>
          <RecipientRelationshipTxt>N/A</RecipientRelationshipTxt>
          <RecipientFoundationStatusTxt>PC</RecipientFoundationStatusTxt>
          <GrantOrContributionPurposeTxt>General &amp; Unrestricted</GrantOrContributionPurposeTxt>
          <Amt>563552</Amt>
        </GrantOrContributionPdDurYrGrp>
        <GrantOrContributionPdDurYrGrp>
          <RecipientBusinessName>
            <BusinessNameLine1Txt>THE UK ONLINE GIVING FOUNDATION</BusinessNameLine1Txt>
          </RecipientBusinessName>
          <RecipientForeignAddress>
            <AddressLine1Txt>6 TRULL FARM BUILDINGS</AddressLine1Txt>
            <CityNm>TRULL TETBURY</CityNm>
            <ProvinceOrStateNm>GLOUCESTERSHIRE</ProvinceOrStateNm>
            <CountryCd>UK</CountryCd>
            <ForeignPostalCd>GL8 8SQ</ForeignPostalCd>
          </RecipientForeignAddress>
          <RecipientRelationshipTxt>N/A</RecipientRelationshipTxt>
          <RecipientFoundationStatusTxt>PC</RecipientFoundationStatusTxt>
          <GrantOrContributionPurposeTxt>General &amp; Unrestricted</GrantOrContributionPurposeTxt>
          <Amt>50008</Amt>
        </GrantOrContributionPdDurYrGrp>
        <GrantOrContributionPdDurYrGrp>
          <RecipientBusinessName>
            <BusinessNameLine1Txt>TIDES FOUNDATION</BusinessNameLine1Txt>
          </RecipientBusinessName>
          <RecipientUSAddress>
            <AddressLine1Txt>PO BOX 399389</AddressLine1Txt>
            <CityNm>SAN FRANCISCO</CityNm>
            <StateAbbreviationCd>CA</StateAbbreviationCd>
            <ZIPCd>94139</ZIPCd>
          </RecipientUSAddress>
          <RecipientRelationshipTxt>N/A</RecipientRelationshipTxt>
          <RecipientFoundationStatusTxt>PC</RecipientFoundationStatusTxt>
          <GrantOrContributionPurposeTxt>COVID-19 Relief Efforts</GrantOrContributionPurposeTxt>
          <Amt>50000</Amt>
        </GrantOrContributionPdDurYrGrp>
        <GrantOrContributionPdDurYrGrp>
          <RecipientBusinessName>
            <BusinessNameLine1Txt>UC SAN DIEGO FOUNDATION - BIRCH AQUARIUM AT SCRIPP</BusinessNameLine1Txt>
          </RecipientBusinessName>
          <RecipientUSAddress>
            <AddressLine1Txt>9500 GILMAN DR MC 0210</AddressLine1Txt>
            <CityNm>LA JOLLA</CityNm>
            <StateAbbreviationCd>CA</StateAbbreviationCd>
            <ZIPCd>92093</ZIPCd>
          </RecipientUSAddress>
          <RecipientRelationshipTxt>N/A</RecipientRelationshipTxt>
          <RecipientFoundationStatusTxt>PC</RecipientFoundationStatusTxt>
          <GrantOrContributionPurposeTxt>Adopt a Class and Sponsor a Child Education Programs</GrantOrContributionPurposeTxt>
          <Amt>25000</Amt>
        </GrantOrContributionPdDurYrGrp>
        <GrantOrContributionPdDurYrGrp>
          <RecipientBusinessName>
            <BusinessNameLine1Txt>UNITED WAY OF DANE COUNTY INC</BusinessNameLine1Txt>
          </RecipientBusinessName>
          <RecipientUSAddress>
            <AddressLine1Txt>2059 ATWOOD AVE</AddressLine1Txt>
            <CityNm>MADISON</CityNm>
            <StateAbbreviationCd>WI</StateAbbreviationCd>
            <ZIPCd>53704</ZIPCd>
          </RecipientUSAddress>
          <RecipientRelationshipTxt>N/A</RecipientRelationshipTxt>
          <RecipientFoundationStatusTxt>PC</RecipientFoundationStatusTxt>
          <GrantOrContributionPurposeTxt>COVID-19 Relief Efforts</GrantOrContributionPurposeTxt>
          <Amt>45000</Amt>
        </GrantOrContributionPdDurYrGrp>
        <TotalGrantOrContriPdDurYrAmt>5525790</TotalGrantOrContriPdDurYrAmt>
      </SupplementaryInformationGrp>
      <AnalysisIncomeProducingActyGrp>
        <FeesContractsFromGovtAgGrp />
        <MembershipDuesAndAssmntGrp />
        <IntOnSavAndTempCashInvstGrp>
          <ExclusionCd>14</ExclusionCd>
          <ExclusionAmt>42513</ExclusionAmt>
        </IntOnSavAndTempCashInvstGrp>
        <DivAndIntFromSecPartVIIGrp />
        <NetRntlIncmReDebtFincdPropGrp />
        <NetRntlIncmReNotDebtFincdProp />
        <NetRentalIncomePersonalPropGrp />
        <OtherInvestmentIncmPartVIIGrp />
        <GainSalesAstOthThanInvntryGrp />
        <NetIncomeLossFromSpecialEvtGrp />
        <GrossProfitLossSlsOfInvntryGrp />
        <SubtotalsIncmProducingActyGrp>
          <ExclusionAmt>42513</ExclusionAmt>
        </SubtotalsIncmProducingActyGrp>
        <TotalIncomeProducingActyAmt>42513</TotalIncomeProducingActyAmt>
      </AnalysisIncomeProducingActyGrp>
      <TrnsfrTransRlnNonchrtblEOGrp>
        <TrnsfrOfCashToNonchrtblEOInd>false</TrnsfrOfCashToNonchrtblEOInd>
        <TrnsfrOtherAssetNonchrtblEOInd>false</TrnsfrOtherAssetNonchrtblEOInd>
        <SalesOrExchangesOfAssetsInd>false</SalesOrExchangesOfAssetsInd>
        <PurchaseOfAssetsNonchrtblEOInd>false</PurchaseOfAssetsNonchrtblEOInd>
        <RentalOfFacilitiesOthAssetsInd>false</RentalOfFacilitiesOthAssetsInd>
        <ReimbursementArrangementsInd>false</ReimbursementArrangementsInd>
        <LoansOrLoanGuaranteesInd>false</LoansOrLoanGuaranteesInd>
        <PerformanceOfServicesEtcInd>false</PerformanceOfServicesEtcInd>
        <SharingOfFacilitiesEtcInd>false</SharingOfFacilitiesEtcInd>
        <RelationshipsNonchrtblEOInd>false</RelationshipsNonchrtblEOInd>
      </TrnsfrTransRlnNonchrtblEOGrp>
    </IRS990PF>
    <IRS990ScheduleB documentId="IRS990ScheduleB">
      <Organization501c3ExemptPFInd>X</Organization501c3ExemptPFInd>
      <GeneralRuleInd>X</GeneralRuleInd>
      <ContributorInformationGrp>
        <ContributorNum>1</ContributorNum>
        <ContributorPersonNm>Illumina Inc</ContributorPersonNm>
        <ContributorUSAddress>
          <AddressLine1Txt>Charles Dadswell 5200 Illumina Way</AddressLine1Txt>
          <CityNm>San Diego</CityNm>
          <StateAbbreviationCd>CA</StateAbbreviationCd>
          <ZIPCd>92122</ZIPCd>
        </ContributorUSAddress>
        <TotalContributionsAmt>5000000</TotalContributionsAmt>
        <PersonContributionInd>X</PersonContributionInd>
      </ContributorInformationGrp>
    </IRS990ScheduleB>
    <AccountingFeesSchedule documentId="AccountingFeesSch">
      <AccountingFeesDetail>
        <CategoryTxt>Audit Fees</CategoryTxt>
        <Amt>15225</Amt>
        <DisbursementsCharitablePrpsAmt>15225</DisbursementsCharitablePrpsAmt>
      </AccountingFeesDetail>
    </AccountingFeesSchedule>
    <CompensationExplanation documentId="CompensationExpl">
      <CompensationExplanationGrp>
        <PersonNm>Karen Possemato</PersonNm>
        <ShortExplanationTxt>* Removed from foundation in 2020</ShortExplanationTxt>
      </CompensationExplanationGrp>
    </CompensationExplanation>
    <DepreciationSchedule documentId="DepreciationSch" />
    <GeneralExplanationAttachment documentId="GeneralExplAttach">
      <GeneralExplanationGrp>
        <IdentifierTxt>Part IX-A (990-PF) -Summary of Direct Charitable Activities</IdentifierTxt>
        <FormAndLineReferenceDesc>Part IX-A (990-PF) -Summary of Direct Charitable Activities</FormAndLineReferenceDesc>
        <MediumExplanationTxt>iHope: $284,205 - Through clinical whole-genome sequencing (cWGS) and philanthropy, the iHope Global Network strives to end years-long diagnostic odysseys in patients with rare and undiagnosed genetic disease. The Network aims to build on scientific and public awareness by demonstrating how next-generation sequencing can create a significant impact - by helping undiagnosed patients and their families find long sought-after answers. Additional global partners are joining the iHope community in 2020 representing every continent on the globe. This provides a rich opportunity to bring these clinical partners together to build on the genetic expertise and clinical experience on how to end the diagnostic odyssey for patients and their families.</MediumExplanationTxt>
      </GeneralExplanationGrp>
    </GeneralExplanationAttachment>
    <LiquidationExplanationStmt documentId="LiquidExpStmt">
      <ExplanationTxt>As explained below, the Foundation has no plans for dissolution. This statement is submitted to report the distribution of certain assets during the year. The distributions resulted in a substantial contraction of assets. The following information is submitted in accordance with Treasury Regulation Section 1.6043-3(a)(1) and the Form 990-PF instructions: During the taxable year ending December 31, 2020, the Foundation made distributions from assets from sources other than current income. Collectively, the distributions in excess of current income totaled $5,525,790. This amount represents 25% or more of the Foundation's net assets of $6,652,810 (as measured by fair market value) at the beginning of the Foundation's taxable year ending December 31, 2020. Although the Foundation technically experienced a substantial contraction, it will continue in existence and has no plans for dissolution. The Foundation made distributions of cash to the grantees listed in the attachment to Part XV, Line 3a; each such grant was made solely for the charitable purpose specified therein.</ExplanationTxt>
    </LiquidationExplanationStmt>
    <LegalFeesSchedule documentId="LegalFeesSch">
      <LegalFeesGrp>
        <CategoryTxt>General Consultations</CategoryTxt>
        <LegalFeesAmt>15646</LegalFeesAmt>
        <DisbursementsCharitablePrpsAmt>15646</DisbursementsCharitablePrpsAmt>
      </LegalFeesGrp>
      <LegalFeesGrp>
        <CategoryTxt>DCA EXP: GENERAL CONSULTATIONS</CategoryTxt>
        <LegalFeesAmt>282032</LegalFeesAmt>
        <DisbursementsCharitablePrpsAmt>282032</DisbursementsCharitablePrpsAmt>
      </LegalFeesGrp>
    </LegalFeesSchedule>
    <OtherExpensesSchedule documentId="OtherExpensesSch">
      <OtherExpensesScheduleGrp>
        <Desc>Administrative Fees</Desc>
        <RevenueAndExpensesPerBooksAmt>19140</RevenueAndExpensesPerBooksAmt>
        <DisbursementsCharitablePrpsAmt>19140</DisbursementsCharitablePrpsAmt>
      </OtherExpensesScheduleGrp>
      <OtherExpensesScheduleGrp>
        <Desc>State or Local Filing Fees</Desc>
        <RevenueAndExpensesPerBooksAmt>210</RevenueAndExpensesPerBooksAmt>
        <DisbursementsCharitablePrpsAmt>210</DisbursementsCharitablePrpsAmt>
      </OtherExpensesScheduleGrp>
    </OtherExpensesSchedule>
    <OtherProfessionalFeesSchedule documentId="OthProfFeesSch">
      <OtherProfessionalFeesDetail>
        <CategoryTxt>ADMINISTRATIVE FEES</CategoryTxt>
        <Amt>250</Amt>
        <DisbursementsCharitablePrpsAmt>250</DisbursementsCharitablePrpsAmt>
      </OtherProfessionalFeesDetail>
      <OtherProfessionalFeesDetail>
        <CategoryTxt>EDUCATION CURRICULUM SERVICES</CategoryTxt>
        <Amt>205400</Amt>
        <DisbursementsCharitablePrpsAmt>205400</DisbursementsCharitablePrpsAmt>
      </OtherProfessionalFeesDetail>
    </OtherProfessionalFeesSchedule>
    <TaxesSchedule documentId="TaxesSchedule">
      <TaxesDetail>
        <CategoryTxt>990-PF Estimated Tax for 2020</CategoryTxt>
        <Amt>300</Amt>
      </TaxesDetail>
      <TaxesDetail>
        <CategoryTxt>990-PF Excise Tax for 2019</CategoryTxt>
        <Amt>338</Amt>
      </TaxesDetail>
    </TaxesSchedule>
  </ReturnData>
</Return>
