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SHS (ADYEY) 2,731.000 SHRS 40036 40036 AGNC INVES 10.0199% PFD 200.0000 SHRS 5154 5154 AGNC INVESTME 7.75% PFD 300.0000 SHRS 7737 7737 ALPHABET INC CLA (GOOGL) 8,320.000 SHRS 1574976 1574976 ALPHABET INC SHS (GOOG) 8,400.000 SHRS 1599696 1599696 AMAZON COM INC COM (AMZN) 5,875.000 SHRS 1288916 1288916 AMAZON COM INC COM (AMZN) 6,800.000 SHRS 1491852 1491852 AMER EXPRESS COMPANY (AXP) 4,000.000 SHRS 1187160 1187160 AMPHENOL CORP CL A NEW (APH) 10,500.000 SHRS 729226 729226 ANALOGDEVICES INC COM (ADI) 2,300.000 SHRS 488658 488658 ANNALY CAPI 9.5834% PFD 200.0000 SHRS 5146 5146 AON PLC REG SHS (AON) 81.000 SHRS 29092 29092 APPLE INC (AAPL) 8,000.000 SHRS 2003360 2003360 APPLE INC (AAPL) 9,760.000 SHRS 2444099 2444099 ARCH CAPITAL GRP LTD BM (ACGL) 521.000 SHRS 48114 48114 ASM INTERNATIONAL - NY REG (ASMY) 57.000 SHRS 32442 32442 ASML HLDG NV NY REG SHS (ASML) 59.000 SHRS 40892 40892 ASTRAZENECA PLC SPND ADR (AZN) 850.000 SHRS 55692 55692 ATLASSIAN CORP PLC (TEAM) 165.000 SHRS 40158 40158 BAE SYS PLC SPN ADR (BAESY) 662.000 SHRS 37840 37840 BECTON DICKINSON CO (BDX) 1,550.000 SHRS 351649 351649 BERKSHIRE HATHAWAY INC (BRKB) 900.000 SHRS 407952 407952 BOSTON SCIENTIFIC CORP (BSX) 5,500.000 SHRS 491260 491260 BROADCOM INC (AVGO) 2,500.000 SHRS 579600 579600 BROADCOM INC (AVGO) 300.000 SHRS 695520 695520 CANADIAN NATURAL RES LTD (CNQ) 931.000 SHRS 28740 28740 CANADIAN PACIFIC RAILWAY (CP) 639.000 SHRS 46244 46244 CHEVRON CORP (CVX) 3,650.000 SHRS 528666 528666 CHEVRON CORP (CVX) 4,400.000 SHRS 637296 637296 CHIPOTLE MEXICAN GRILL (CMG) 7,010.000 SHRS 422703 422703 CHURCH&DWIGHT CO INC (CHD) 4,805.000 SHRS 503132 503132 CISCO SYSTEMS INC (CSCO) 10,745.000 SHRS 636104 636104 COMPASS GROUP PLC SHS ADR (CMPGY) 1,096.000 SHRS 36815 36815 COOPER COS INC (COO) 6,280.000 SHRS 577320 577320 COSTCO WHOLESALE CRP DEL (COST) 1,000.000 SHRS 916270 916270 COSTCO WHOLESALE CRP DEL (COST) 1,100.000 SHRS 1007897 1007897 COUPANG INC REGSHS CLA (CPNG) 1,909.000 SHRS 41960 41960 CROWDSTRIKEHLDGS INC (CRWD) 1,100.000 SHRS 376376 376376 DANAHER CORP DEL COM (DHR) 3,000.000 SHRS 688650 688650 DISNEY (WALT) CO COM STK (DIS) 5,900.000 SHRS 656965 656965 EATON CORP PLC (ETN) 1,000.000 SHRS 331870 331870 ECOLAB INC (ECL) 1,410.000 SHRS 330391 330391 ENBRIDGE INC 4% PFD 278.0000 SHRS 6269 6269 EOG RESOURCES INC (EOG) 4,130.000 SHRS 506255 506255 EOG RESOURCES INC (EOG) 4,400.000 SHRS 539352 539352 EXPERIAN PLC SP ADR (EXPGY) 650.000 SHRS 27775 27775 FERGUSON PLC REG SHS (FERG) 179.000 SHRS 31069 31069 FERRARI NV (RACE) 154.000 SHRS 65425 65425 FORTIVE CORP (FTV) 4,600.000 SHRS 345000 345000 HILTON WORLDWIDE HOLDINGS INC (HLT) 5000.000 SHRS 1235800 1235800 HOME DEPOT INC (HD) 1,545.000 SHRS 600990 600990 HOME DEPOT INC (HD) 2,050.000 SHRS 797430 797430 ICIC BANK LTD SPD ADR (IBN) 1,341.000 SHRS 40042 40042 ICON PLC (ICLR) 244.000 SHRS 51169 51169 INTERCONTINENTAL (ICE) 4,005.000 SHRS 596785 596785 JACOBS SOLUTIONS INC REG (SHS) 3,500.000 SHRS 467670 467670 JOHNSON AND JOHNSON COM (JNJ) 3,023.000 SHRS 437186 437186 JPMORGAN CHASE & CO (JPM) 2,145.000 SHRS 514178 514178 JPMORGAN CHASE & CO (JPM) 2,400,000.000 SHRS 575304 575304 KEYCORP 6.125% PFD 300.0000 SHRS 7365 7365 KEYCORP 6.2% PFD 175.0000 SHRS 4268 4268 KKR & CO INC (KKR) 4,165.000 SHRS 616045 616045 LINDE PLC REG SHS (LIN) 1,300.000 SHRS 544271 544271 LINDE PLC REG SHS (LIN) 97.000 SHRS 40611 40611 MASTERCARD INC (MA) 1,755.000 SHRS 924130 924130 MCDONALDS CORP (MDC) 1,900.000 SHRS 550791 550791 MCDONALDS CORP (MDC) 2,010.000 SHRS 582679 582679 MEITUAN ADR (MPNGY) 1,281.000 SHRS 49716 49716 MERCADO LIBRE INC (MELI) 17.000 SHRS 28907 28907 MERCK AND CO INC SHS (MRK) 3,150.000 SHRS 313362 313362 META PLATFORMS INC (META) 1,000.000 SHRS 585510 585510 META PLATFORMS INC (META) 1,595.000 SHRS 933888 933888 MICROSOFT CORP (MSFT) 4,500.000 SHRS 1896750 1896750 MICROSOFT CORP (MSFT) 5,120.000 SHRS 2158080 2158080 MITSUBISHI HEAVY (MHVIY) 1,845.000 SHRS 51623 51623 MONDAY.COM LTD. REGSHS (MNDY) 151.000 SHRS 35551 35551 MORGAN STANLEY (MS) 5,705.000 SHRS 717233 717233 NEXTERA ENERGY INC SHS (NEE) 8,400.000 SHRS 602196 602196 NMDIA (NVDA) 10,230.000 SHRS 1373787 1373787 NORTHROP GRUMMAN CORP (NOC) 900.000 SHRS 422361 422361 NOVO NORDISK A S ADR (NVO) 829.000 SHRS 71311 71311 NU HOLDINGS LTD REG SHS (NU) 2,869.000 SHRS 29723 29723 O'REILLY AUTOMOTIVE INC (ORLY) 200.000 SHRS 237160 237160 OTIS WORLDWIDE CORP REG (OTIS) 4,240.000 SHRS 392666 392666 PALO ALTO NETWORKS INC (PANW) 3,800.000 SHRS 691448 691448 PARKER HANNIFIN CORP (PH) 2,000.000 SHRS 1272060 1272060 PEPSICO INC (PEP) 3,000.000 SHRS 456180 456180 PROCTER & GAMBLE CO (PG) 2,500.000 SHRS 419125 419125 PROGRESSIVE CRP OHIO (PGR) 4,000.000 SHRS 958440 958440 REGIONS FINL 6.95% PFD 225.0000 UNITS 5904 5904 REGIONS FINL C 5.7% PFD 200.0000 SHRS 4848 4848 ROLLS ROYCE GRP SPN ADR (RYCEY) 7,433.000 SHRS 52881 52881 ROPER TECHNOLOGIES INC (ROP) 1,400.000 SHRS 727790 727790 RTX CORP (RTX) 4,039.000 SHRS 467393 467393 S&P GLOBAL INC (SPGI) 1,370.000 SHRS 682301 682301 SAFRANSA-UNSPONSERED ADR (SAFRY) 1242.000 SHRS 67689 67689 SALESFORCE COM INC (CRM) 3,135.000 SHRS 1048125 1048125 SAP SE SHS (SAP) 269.000 SHRS 66230 66230 SCHNEDER ELEC SE ADR (SBGSY) 817.000 SHRS 40556 40556 SCHWAB CHARLES CORP NEW (SCHW) 9,300.000 SHRS 688293 688293 SEA LTD (SE) 647.000 SHRS 68647 68647 SERVICENOW INC (NOW) 1,100.000 SHRS 1166132 1166132 SERVICENOW INC (NOW) 555.000 SHRS 588367 588367 SIEMENS ENERGY AG-UNSP (SMNEY) 887.000 SHRS 46389 46389 SPOTIFY TECH S.A. REG (SPOT) 141.000 SHRS 63080 63080 STERIS PLC REG SHS (STE) 186.000 SHRS 38234 38234 STRYKER CORP (SYK) 1,500.000 SHRS 540075 540075 STRYKER CORP (SYK) 850.000 SHRS 306043 306043 TAIWAN S MANUFCTRING ADR ( TSM) 455.000 SHRS 89858 89858 THERMO FISHER SCIENTIFIC INC (TMO) 825.000 SHRS 429190 429190 TJX COS INC NEW (TJX) 5,780.000 SHRS 698282 698282 TRANE TECHNOLOGIES PLC (TT) 3,500.000 SHRS 1292725 1292725 UBS GROUP AG NAMEN-AKT (UBS)1,129.000 SHRS 34231 34231 UNITEDHEALTH GROUP INC (UNH) 1,500.000 SHRS 758790 758790 US CELLULAR COR 6.25%PFD 200.0000 UNITS 4624 4624 VISA INC CL A SHRA (V) 2,800.000 SHRS 884912 884912 VULCANMATERIALSCO (VMC) 1,600.000 SHRS 411568 411568 WALMART INC (WMT) 6,705.000 SHRS 605797 605797 WASTE CONNECTIONS INC (WCN) 161.000 SHRS 27624 27624 WESCO INTER 10.625% PFD 200.0000 SHRS 5104 5104 WESTERN ALLIA 4.25% PFD 150.0000 UNITS 3326 3326 ZOETIS INC (ZTS) 2,700.000 SHRS 439911 439911 ZOETIS INC (ZTS) 3,860.000 SHRS 628910 628910 7035431 7035431 0 0 AVORO LIFE SCIENCES OFFSHORE FUND LTD. FMV 1202697 1202697 SHARES TR RUSSELL2000 (IWM) 5,200.000 SHRS FMV 1148992 1148992 VANGUARD SMALL CAP (VB) 9,000.000 SHRS FMV 2162520 2162520 VANGUARD MID-CAPETF (VO) 1,700.000 SHRS FMV 449021 449021 FILING FEES 1500 0 1500 INSURANCE 9839 0 9839 DEPOSITORY FEES 480 480 0 SECURITY LITIGATION PROCEEDS 20551 20551 20551 CHANGE IN INVESTMENT UNREALIZED GAIN 5042755 INVESTMENT ADVISORY FEES 367268 367268 0 CUSTODY FEES 15750 15750 0 FEDERAL EXCISE TAX 80000 0 0 FOREIGN WITHHOLDING TAXES 2071 2071 0