2025-08-08T12:55:18-05:00 2024-09-30 911194016 CLARK NUBER PS 10900 NE 4TH STREET SUITE 1400 BELLEVUE WA 98004 990 2023-10-01 910667886 PACIFIC NORTHWEST RESEARCH INSTITUTE PACI 2067261200 720 BROADWAY SEATTLE WA 98122 DIONNE GORDON CFAO 2067261200 2025-08-05 1 0 MEGAN R RYAN P00737884 4254544919 2025-08-05 2023 2025-03-06 01:10:19Z DIONNE GORDON 720 BROADWAY SEATTLE WA 98122 11630531 0 X WWW.PNRI.ORG X 1956 WA AN INDEPENDENT, BIOMEDICAL RESEARCH INSTITUTE AIMED AT UNDERSTANDING HOW HEALTH IS MAINTAINED IN THE FACE OF GENETIC AND ENVIRONMENTAL RISKS ASSOCIATED WITH DISEASE DEVELOPMENT. 9 9 95 9 0 0 5162453 5105774 6816 12513 42751 133214 406735 216303 5618755 5467804 33741 18127 0 0 7480230 7057078 0 0 199491 3981547 3784848 11495518 10860053 -5876763 -5392249 16806789 13215750 1031801 886167 15774988 12329583 X PACIFIC NORTHWEST RESEARCH INSTITUTE (PNRI), A NONPROFIT CORPORATION, IS AN INDEPENDENT, BIOMEDICAL RESEARCH INSTITUTE CONDUCTING BASIC AND APPLIED RESEARCH AIMED AT UNDERSTANDING HOW HEALTH IS MAINTAINED IN THE FACE OF GENETIC AND ENVIRONMENTAL RISKS ASSOCIATED WITH DISEASE DEVELOPMENT. THE SCIENTIFIC DISCOVERIES HAVE APPLICABILITY IN A VARIETY OF DISEASES, INCLUDING DIABETES, CANCER, NEUROLOGICAL DISORDERS, AMONG MANY OTHERS. 0 0 5132684 12513 THE STUBBS LAB IS FOCUSED ON UNDERSTANDING HOW THE INTERPLAY BETWEEN GENES AND ENVIRONMENT SHAPES BRAIN DEVELOPMENT, AND HOW THAT INTERPLAY ULTIMATELY INFLUENCES BEHAVIOR. WE STUDY THE FOLE OF GENE REGULATION, THE PROCESSES RESPONSIBLE FOR ORCHESTRATING HOW GENES ARE USED IN EACH BRAIN CELL TO SPECIFY UNIQUE FUNCTIONS AND HOW WHAT HAPPENS DURING OUR LIFETIME LEADS TO CHANGES IN THOSE PROCESSES. 1306340 18127 EXPERIMENTING IN YEAST ALLOWS THE DUDLEY LAB TO MAKE DISCOVERIES THAT GO BEYOND THE LAB WITH THE POWER TO CHANGE HOW SCIENTISTS AROUND THE GLOBE APPROACH GENETIC RESEARCH. FROM PERFORMING LARGESCALE EXPERIMENTS TO DISCOVERING NEW ANTIFUNGAL TREATMENTS, THE DUDLEY LAB IS A WORLD LEADER IN USING YEAST TO ANSWER FUNDAMENTAL QUESTIONS ABOUT BIOLOGY. WE ARE PASSIONATE ABOUT APPLYING AND DEVELOPING NOW TECHNOLOGIES AND ABOUT TRANSLATING DISCOVERIES FROM OUR LAB INTO REALWORLD APPLICATIONS. THE DUDLEY LAB EXPERIMENTS IN YEAST BECAUSE YEAST CELLS FUNCTION IN MUCH THE SAME WAY AS HUMAN CELLS. HOWEVER, WITH YEAST, WE CAN PERFORM EXPERIMENTS MUCH FASTER, AND ON A GRANDER SCALE, THAN SCIENTISTS CAN WITH HUMAN CELLS. 1226602 THE CARVALHO LAB STUDIES HOW, WHEN, AND WHY HUMAN GENOMIC VARIANTS OCCUR AND CONTRIBUTE TO THE DEVELOPMENT OF DISEASE AND DISABILITY. 1110310 THE HAGOPIAN LAB RESEARCHES WAYS TO PREDICT AND PREVENT THE DEVELOPMENT OF TYPE 1 DIABETES, A DISEASE AFFECTING OVER ONE MILLION AMERICAN CHILDREN AND ADULTS. NOT EVERYONE WITH GENETIC RISK FOR TYPE 1 DIABETES DEVELOPS THE DISEASE. WHY NOT? SCIENTISTS IN THE HAGOPIAN LAB BELIEVE ANSWERS LIE IN THE ENVIRONMENT. THEY ARE ONE OF 6 LABS PARTICIPATING IN AN INTERNATIONAL STUDY FOLLOWING 8,000 CHILDREN WITH HIGH GENETIC RISK FOR TYPE 1 DIABETES. THE HAGOPIAN LAB ALSO DEVELOPS POPULATION BASED NEWBORN SCREENING METHODS TO PREDICT WHO IS AT RISK. THE ULTIMATE GOAL IS TO PREVENT THE DISEASE ENTIRELY. 1110310 8775936 1 1 0 0 0 0 0 0 0 1 1 0 0 1 1 0 1 0 0 0 0 0 0 0 1 0 0 0 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 21 0 95 1 0 0 0 0 0 1 1 0 0 0 0 0 0 X 9 9 0 0 0 0 0 0 0 1 1 0 0 0 1 1 1 1 1 1 1 0 WA X DIONNE GORDON 2067261200 720 BROADWAY SEATTLE WA 98122 GARY KOCHER BOARD CHAIR 2.00 X X 0 0 0 ALLISON HANDY BOARD SECRETARY 1.50 X X 0 0 0 MATTHEW GAGNIER BOARD TREASURER 2.00 X X 0 0 0 TOM HAYWARD BOARD MEMBER 2.00 X 0 0 0 TERA EERKES BOARD MEMBER 2.00 X 0 0 0 CINDY HABA BOARD MEMBER 2.00 X 0 0 0 STEPHAN MARTINEZ BOARD MEMBER 2.00 X 0 0 0 LINDA MAUZY BOARD MEMBER 2.00 X 0 0 0 SHIRIN MCCONAGHY BOARD MEMBER 2.00 X 0 0 0 JOHN WECKER CEO THRU 12/23 40.00 X 367305 0 34492 DIONNE GORDON CFAO 40.00 X 145283 0 0 JACK FARIS CEO FROM 01/24 40.00 X 0 0 0 AIMEE DUDLEY PRINCIPAL INVESTIGATOR 40.00 X 201775 0 30000 WILLIAM HAGOPIAN PRINCIPAL INVESTIGATOR 40.00 X 189820 0 30000 LISA STUBBS PRINCIPAL INVESTIGATOR 40.00 X 232631 0 30000 JUSTIN DUKES DIRECTOR IT 40.00 X 153585 0 0 CLAUDIA FONSECA ASSISTANT INVESTIGATOR 40.00 X 135802 0 4235 RICHARD MCLAUGHLIN ASSISTANT PRINCIPAL INVESTIGATOR 40.00 X 140805 0 20874 MICHAEL METZGER ASSISTANT PRINCIPAL INVESTIGATOR 40.00 X 127401 0 24238 SHANNON BOWEN CHIEF ADVANCEMENT OFFICER 40.00 X 189719 0 25668 1884126 0 199507 15 0 1 0 LHH RECRUITMENT SOLUTIONS DEPT CH 14031 PALATINE IL 600554031 HR CONSULTANT FEES 116321 1 115374 3543884 1446516 5105774 VIVARIUM REVENUE 900099 12513 12513 12513 102041 102041 315865 60511 255354 255354 255354 6062838 6031665 31173 31173 31173 31500 115374 70551 -39051 -39051 5467804 12513 0 349517 X 18127 18127 1104754 520084 584670 4676104 4391736 202155 82213 97853 87112 9045 1696 674522 586067 78148 10307 503845 427664 69027 7154 236935 114092 122843 102257 102257 1125557 943483 155860 26214 83170 61439 7972 13759 684953 531604 145366 7983 64781 43468 12579 8734 19259 10709 6907 1643 3291 3291 461416 391646 63214 6556 EQUIPMENT RENT, MAINT. 376053 321980 49219 4854 SUBCONTRACTS 279395 274725 4670 LICENSES, DUES, FEES 179279 48949 101952 28378 BAD DEBT 157496 157496 11006 3051 7955 10860053 8775936 1884626 199491 169049 500943 4375645 866892 565634 599255 123293 21516 4500 4500 199460 130370 15106791 11719234 3813523 3387557 2520557 1534819 45783 11091 4989345 6158807 16806789 13215750 920057 881967 100000 0 11744 4200 1031801 886167 X 10291892 5300578 5483096 7029005 15774988 12329583 16806789 13215750 X -5392249 777382 1169462 X 0 1 X 1 1 1 X 20450636 6597150 6134304 5162453 5105774 43450317 20450636 6597150 6134304 5162453 5105774 43450317 15744825 27705492 482111 463827 439218 467192 417906 2270254 1389 9005 6439 26068 42901 45763472 21979 0.60540 0.59900 X SCHEDULE A, PART II, LINE 10, EXPLANATION OF OTHER INCOME: MISCELLANEOUS INCOME - 2019 AMOUNT: $ 846. 2021 AMOUNT: $ 17. 2022 AMOUNT: $ 13,344. 2023 AMOUNT: $ 0. REBATES - 2019 AMOUNT: $ 543. 2020 AMOUNT: $ 9,005. 2021 AMOUNT: $ 6,422. 2022 AMOUNT: $ 12,724. 2023 AMOUNT: $ 0. RESTRICTED RESTRICTED RESTRICTED RESTRICTED RESTRICTED RESTRICTED RESTRICTED RESTRICTED 475000 20583 20583 475000 475000 20466 20466 475000 75000 400000 347 347 475000 75000 164 164 75000 75000 131 131 75000 0.00000 1.00000 0.00000 1 0 823359 823359 9701466 7762210 1939256 4581966 3957024 624942 3387557 BENEFICIAL INTEREST IN PERPETUAL TR 6158807 6158807 TENANT DEPOSITS 4200 4200 7533197 777382 1240013 2017395 5515802 -47998 -47998 5467804 10978602 131062 131062 10847540 12513 12513 10860053 PART V, LINE 4: THE ORGANIZATION'S ENDOWMENT FUNDS ARE DESIGNATED FOR USE AS OPERATING RESERVES AND SCIENTIST RECRUITMENT. PART XI, LINE 2D - OTHER ADJUSTMENTS: GAIN ON PERPETUAL TRUST 1,169,462. SPECIAL EVENT EXPENSES REPORTED ON PART VIII 70,551. PART XI, LINE 4B - OTHER ADJUSTMENTS: RENTAL EXPENSES REPORTED ON PART VIII -60,511. VIVARIUM REVENUE REPORTED ON PART VIII 12,513. PART XII, LINE 2D - OTHER ADJUSTMENTS: RENTAL EXPENSES REPORTED ON PART VIII 60,511. SPECIAL EVENT EXPENSES REPORTED ON PART VIII 70,551. PART XII, LINE 4B - OTHER ADJUSTMENTS: VIVARIUM REVENUE REPORTED ON PART VIII 12,513. BOLD BREAKTHROUGHS 146874 115374 31500 24213 31519 14819 146874 115374 31500 24213 31519 14819 70551 -39051 1 TUITION 1 18127 COST TUITION REDUCTION PAYMENTS PART I, LINE 2: THE ORGANIZATION HAS A FORMAL AGREEMENT WITH A UNIVERSITY WHICH INCLUDES TUITION REDUCTION FOR STUDENTS WHO WORK AT PNRI LABS. X X X X 0 0 0 0 0 0 0 0 0 JOHN WECKER CEO THRU 12/23 367305 0 0 0 0 0 30000 0 4492 0 401797 0 0 0 LISA STUBBS PRINCIPAL INVESTIGATOR 232631 0 0 0 0 0 30000 0 0 0 262631 0 0 0 AIMEE DUDLEY PRINCIPAL INVESTIGATOR 201775 0 0 0 0 0 30000 0 0 0 231775 0 0 0 WILLIAM HAGOPIAN PRINCIPAL INVESTIGATOR 189820 0 0 0 0 0 30000 0 0 0 219820 0 0 0 SHANNON BOWEN CHIEF ADVANCEMENT OFFICER 189719 0 0 0 0 0 21988 0 3680 0 215387 0 0 0 RICHARD MCLAUGHLIN ASSISTANT PRINCIPAL INVESTIGATOR 140805 0 0 0 0 0 20874 0 0 0 161679 0 0 0 JUSTIN DUKES DIRECTOR IT 153585 0 0 0 0 0 0 0 0 0 153585 0 0 0 MICHAEL METZGER ASSISTANT PRINCIPAL INVESTIGATOR 127401 0 0 0 0 0 19270 0 4968 0 151639 0 0 0 FORM 990, PART I, LINE 6: VOLUNTEERS CONSIST OF UNCOMPENSATED BOARD MEMBERS WHO GAVE THEIR TIME DURING THE YEAR. THE BOARD OF TRUSTEES PROVIDES LEADERSHIP AND SUPPORT TO HELP EXECUTIVE MANAGEMENT MAKE GOOD DECISIONS FOR THE GREATER GOOD OF PNRI'S MISSION. FORM 990, PART VI, SECTION B, LINE 11B THE CEO, CFAO, CHIEF ADVANCEMENT OFFICER AND FINANCE COMMITTEE CHAIR WILL REVIEW THE FORM 990 PRIOR TO FILING WITH THE IRS. THE PUBLIC DISCLOSURE COPY WILL BE DISTRIBTED AND DISCUSSED AT A SUBSEQUENT BOARD MEETING. ELECTRONIC COPIES OF THE PUBLIC DISCLOSURE VERSION OF FORM 990 WILL BE DISTRIBUTED TO THE ENTIRE BOARD, AND PHYSICAL COPIES OF THE FULL FORM 990 WILL BE MADE AVAILABLE ONSITE UPON REQUEST. FORM 990, PART VI, SECTION B, LINE 12C ANNUALLY, PER INSTITUTE CONFLICT OF INTEREST POLICY THE FINANCE & AUDIT COMMITTEE SUBMITS A BOARD QUESTIONNAIRE TO ALL TRUSTEES AND KEY STAFF. ALL RESPONSES ARE GATHERED AND REVIEWED BY THE COMMITTEE CHAIR AND THE CFAO. THE RESULTS ARE DISCUSSED AT THE FINANCE & AUDIT COMMITTEE MEETING. THE COMMITTEE CHAIR THEN PRESENTS THE RESULTS TO THE FULL BOARD AND ACTION IS TAKEN AS NEEDED. IF A POTENTIAL CONFLICT OF INTEREST AROSE DURING THE YEAR, THE BOARD MEMBER WOULD CONTACT OUR COMMITTEE CHAIR AND DISCLOSE THE MATTER AND BOARD REVIEW AND ACTION WOULD BE TAKEN AT THE NEXT MEETING TO ALERT ALL MEMBERS. FORM 990, PART VI, SECTION B, LINE 15 THE CEO, CFAO, AND KEY EMPLOYEES HAVE THEIR INITIAL SALARY AND ANY NON-COST OF LIVING ADJUSTMENT INCREASES DOCUMENTED BY A SALARY SURVEY PROCESS CONDUCTED BY OUR INDEPENDENT HUMAN RESOURCES CONSULTING FIRM. IN ADDITION, THE CEO CONTRACT IS APPROVED BY BOARD EXECUTIVE COMMITTEE. COMPENSATION REVIEWS ARE PERFORMED ANNUALLY. FORM 990, PART VI, SECTION C, LINE 19 GOVERNING DOCUMENTS, CONFLICT OF INTEREST POLICY AND FINANCIAL STATEMENTS ARE AVAILABLE UPON REQUEST. FORM 990, PART IX, LINE 11G OTHER FEES: PROGRAM SERVICE EXPENSES 943,483. MANAGEMENT AND GENERAL EXPENSES 155,860. FUNDRAISING EXPENSES 26,214. TOTAL EXPENSES 1,125,557. FORM 990, PART XI, LINE 9: GAIN ON PERPETUAL TRUST 1,169,462.