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      <SupplementalInformationDetail>
        <FormAndLineReferenceDesc>Schedule D, Part V, Line 4</FormAndLineReferenceDesc>
        <ExplanationTxt>The endowment funds were established to support a variety of purposes, including research, scholarships, the MBL library, and plant.</ExplanationTxt>
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        <FormAndLineReferenceDesc>Schedule D, Part X, Line 2</FormAndLineReferenceDesc>
        <ExplanationTxt>The Laboratory is a tax exempt organization as described in Section 501(c)(3) of the Internal Revenue Code, as amended (the Code), and is generally exempt from income taxes pursuant to Section 501(a) of the Code. The Laboratory is required to assess uncertain tax positions and has determined that there were no such positions that are material to the financial statements. Management believes that the Laboratory's income tax returns for years ended prior to 2015 are no longer subject to examination by tax authorities in its major tax jurisdiction. On December 22, 2017, the President signed into law H.R. 1, originally known as the Tax Cuts and Jobs Act. The new law includes several provisions that result in substantial changes to the tax treatment of tax exempt organizations and their donors. The Laboratory has reviewed these provisions and the potential impact and concluded the enactment of H.R. 1 will not have a material effect on the operations of the organization.</ExplanationTxt>
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        <ExplanationTxt>Decrease in value of interest rate swap agreement of $1,101,154. Decrease in value of annuities of $2210. Decrease in post-retirement health care liability of $245,493.</ExplanationTxt>
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        <ExplanationTxt>All trustees, officers, senior faculty, senior administrators, and other employees of the Laboratory are subject to conflict of interest policies that among other things, define material financial disclosure of information and specify procedures to be followed in managing these conflicts. The Laboratory's conflict of interest (COI) policies for trustees and officers requires disclosure whenever a trustee or a related party engages in an activity that could be considered a conflict of interest. Trustees are reminded that questions regarding the COI policy may be raised informally and confidentially at any time with the Chair of the Board of Trustees, the Chair of the Nominating and Governance Committee, or the University of Chicago's General Counsel. All trustees must annually disclose actual and potential conflicts of interest by completing a confidential COI Disclosure Statement and Acknowledgement, and these disclosures must be updated as new information becomes available that could affect the trustee's stated interests. The MBL's Director of Finance, in consultation with the Nominating and Governance Committee and University of Chicago's General Counsel, will compile the disclosures into a confidential database and prepare for each trustee a written acknowledgement of the disclosure that identifies any pending Laboratory transactions that may be affected by the disclosure. The Chair of the Board of Trustees will also review all disclosed potential conflicts of interest before making Board committee assignments. Regardless of these efforts, Trustees must be alert to any and all potential conflicts. To the extent a potential conflict has not been addressed, it should be brought to the immediate attention of the Chair of the Board, the Chair of the Nominating and Governance Committee, or the University of Chicago's General Counsel. The Trustee should also abstain from participating in or voting on the matter. Actions in this regard will be reflected in any official meeting minutes. The Laboratory requires that employees (MBL staff members) complete a COI statement annually. The statement is reviewed by the Director of Human Resources and the Director of the Division of Research. If it is believed there may be a conflict of interest on any of the statements, it is brought to the attention of the MBL Compliance Committee for resolution. Any MBL staff member who is or will be involved in an MBL business transaction in which a potential for conflict of interest may exist is required to report such potential conflict to the Chief Operating Officer. The MBL shall take action to ensure that the transaction, if it is to proceed, is on fair and reasonable terms and in the best interest of the Laboratory. Someone other than the individual with the conflict must initiate the resolutions for action and make the necessary decisions and control the transaction(s). The individual with the conflict must recuse themselves from the decision-making process.</ExplanationTxt>
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        <ExplanationTxt>The Conflict of Interest policy is available on MBL's website. Audited financial statements and Form 990 are available upon request to organization. In addition, audited financial statements, Form 990, and governing documents are available on public websites and the Commonwealth of Massachusetts' website.</ExplanationTxt>
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        <ExplanationTxt>Adjustments for non-operating activities: deduct change in value of interest rate swap agreement of $1,101,154; deduct change in value of annuities of $2,210; and add change in post-retirement healthcare plan liability of $245,493.</ExplanationTxt>
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      <RentalOfFacilitiesToOthOrgInd>0</RentalOfFacilitiesToOthOrgInd>
      <RentalOfFcltsFromOthOrgInd>0</RentalOfFcltsFromOthOrgInd>
      <PerformOfServicesForOthOrgInd>0</PerformOfServicesForOthOrgInd>
      <PerformOfServicesByOtherOrgInd>1</PerformOfServicesByOtherOrgInd>
      <SharingOfFacilitiesInd>0</SharingOfFacilitiesInd>
      <PaidEmployeesSharingInd>1</PaidEmployeesSharingInd>
      <ReimbursementPaidToOtherOrgInd>0</ReimbursementPaidToOtherOrgInd>
      <ReimbursementPaidByOtherOrgInd>1</ReimbursementPaidByOtherOrgInd>
      <TransferToOtherOrgInd>0</TransferToOtherOrgInd>
      <TransferFromOtherOrgInd>1</TransferFromOtherOrgInd>
      <SupplementalInformationDetail>
        <FormAndLineReferenceDesc>Schedule R, Part II</FormAndLineReferenceDesc>
        <ExplanationTxt>The University of Chicago, a 501(c)(3) organization, is the direct controlling organization of the Marine Biological Laboratory. For purposes of completion, the following information is provided: The related organizations listed below are disregarded entities of the University of Chicago: UChicago Argonne LLC -68-0628477, 5801 S. Ellis Avenue, Chicago, IL 60637, Primary Activity: Manage Lab, Legal Domicile: Illinois; University of Chicago Foundation Ltd - 98-0525557, 5th FL Alder Castle, 10 Noble, London, United Kingdom, Primary Activity: Fundraising, Legal Domicile: United Kingdom; Theory and Computing Sciences Building Trust - 51-6596577 - 5801 S. Ellis Avenue, Chicago, IL 60637, Primary Activity: Research Building, Legal Domicile: Illinois; UChicago Trading - 30-0517735, 5801 S. Ellis Avenue, Chicago, IL 60637, Primary Activity: Investing, Legal Domicile: Illinois; Maroon Investments LLC - 5801 S. Ellis Avenue, Chicago, IL 60637, Primary Activity: Holding Company, Legal Domicile: Delaware; UChicago Impact LLC - 61-1682394, 1307 E. 60th Street, Chicago, IL 60637, Primary Activity: Education, Legal Domicile: Illinois; Harper Court LLC - 5801 S. Ellis Avenue, Chicago, IL 60637, Primary Activity: Holding Company, Legal Domicile: Illinois; LPA Management LLC - 5801 S. Ellis Avenue, Chicago, IL 60637, Primary Activity: Property Management, Legal Domicile: Illinois. For purposes of completeness, please note the following: The entities listed below are disregarded entities of The University of Chicago Medical Center: UCMC Community Physicians LLC, 5841 S. Maryland Ave., Chicago, IL 60637, EIN: 38-3865637, Primary Activity: Physician Services, Legal Domicile: Illinois; University of Chicago Medicine Care Network LLC, 5841 S. Maryland Ave., Chicago, IL 60637, EIN: 47-4222269, Primary Activity: Healthcare, Legal Domicile: Illinois; UCM Global LLC, 5841 S. Maryland Ave., Chicago, IL 60637, EIN: 32-0579811, Primary Activity: International Medical Consulting, Legal Domicile: Illinois. Also note: The University of Chicago Medical Center is a less than 50% member in a joint venture with UCMC/SCH Oncology JV LLC, a tax exempt entity, 1850 Silver Cross Blvd, New Lenox, IL 60451, EIN: 32-2436795. The University of Chicago Medicine Care Network, LLC, a disregarded entity of the University of Chicago Medical Center, is the sole member of the following related entities: UCM Care Network Medical Group Inc. 5841 S. Maryland Ave., Chicago, IL 60637, EIN: 47-4221241, Primary Activity: Healthcare, Legal Domicile: Illinois; University of Chicago Medicine Care Network Affiliated Physicians LLC, 5841 S. Maryland, Chicago, IL 60637, EIN: 47-4233918, Primary Activity: Healthcare, Legal Domicile: Illinois. The following entity is a disregarded entity of UChicago Research International, a related entity: UChicago Research Bangladesh LLC, 5801 S. Ellis Avenue, Chicago, IL 60637, Primary Activity: Support Research, Legal Domicile: Illinois.</ExplanationTxt>
      </SupplementalInformationDetail>
    </IRS990ScheduleR>
  </ReturnData>
</Return>