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        <PersonNm>JESSICA GROSSMAN</PersonNm>
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        <BonusFilingOrganizationAmount>200880</BonusFilingOrganizationAmount>
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        <OtherCompensationFilingOrgAmt>1760</OtherCompensationFilingOrgAmt>
        <OtherCompensationRltdOrgsAmt>0</OtherCompensationRltdOrgsAmt>
        <DeferredCompensationFlngOrgAmt>240050</DeferredCompensationFlngOrgAmt>
        <DeferredCompRltdOrgsAmt>0</DeferredCompRltdOrgsAmt>
        <NontaxableBenefitsFilingOrgAmt>35961</NontaxableBenefitsFilingOrgAmt>
        <NontaxableBenefitsRltdOrgsAmt>0</NontaxableBenefitsRltdOrgsAmt>
        <TotalCompensationFilingOrgAmt>970340</TotalCompensationFilingOrgAmt>
        <TotalCompensationRltdOrgsAmt>0</TotalCompensationRltdOrgsAmt>
        <CompReportPrior990FilingOrgAmt>200880</CompReportPrior990FilingOrgAmt>
        <CompReportPrior990RltdOrgsAmt>0</CompReportPrior990RltdOrgsAmt>
      </RltdOrgOfficerTrstKeyEmplGrp>
      <RltdOrgOfficerTrstKeyEmplGrp>
        <PersonNm>BRADLEY LUKE</PersonNm>
        <TitleTxt>CHIEF FINANCE OFFICER</TitleTxt>
        <BaseCompensationFilingOrgAmt>256110</BaseCompensationFilingOrgAmt>
        <CompensationBasedOnRltdOrgsAmt>39834</CompensationBasedOnRltdOrgsAmt>
        <BonusFilingOrganizationAmount>82404</BonusFilingOrganizationAmount>
        <BonusRelatedOrganizationsAmt>12817</BonusRelatedOrganizationsAmt>
        <OtherCompensationFilingOrgAmt>2312</OtherCompensationFilingOrgAmt>
        <OtherCompensationRltdOrgsAmt>360</OtherCompensationRltdOrgsAmt>
        <DeferredCompensationFlngOrgAmt>93649</DeferredCompensationFlngOrgAmt>
        <DeferredCompRltdOrgsAmt>14566</DeferredCompRltdOrgsAmt>
        <NontaxableBenefitsFilingOrgAmt>9382</NontaxableBenefitsFilingOrgAmt>
        <NontaxableBenefitsRltdOrgsAmt>1459</NontaxableBenefitsRltdOrgsAmt>
        <TotalCompensationFilingOrgAmt>443857</TotalCompensationFilingOrgAmt>
        <TotalCompensationRltdOrgsAmt>69036</TotalCompensationRltdOrgsAmt>
        <CompReportPrior990FilingOrgAmt>82404</CompReportPrior990FilingOrgAmt>
        <CompReportPrior990RltdOrgsAmt>12817</CompReportPrior990RltdOrgsAmt>
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      <RltdOrgOfficerTrstKeyEmplGrp>
        <PersonNm>ETHAN KNOWLDEN</PersonNm>
        <TitleTxt>SENIOR CORPORATE COUNSEL/BOD SECRETA</TitleTxt>
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        <CompensationBasedOnRltdOrgsAmt>36623</CompensationBasedOnRltdOrgsAmt>
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        <BonusRelatedOrganizationsAmt>0</BonusRelatedOrganizationsAmt>
        <OtherCompensationFilingOrgAmt>1930</OtherCompensationFilingOrgAmt>
        <OtherCompensationRltdOrgsAmt>300</OtherCompensationRltdOrgsAmt>
        <DeferredCompensationFlngOrgAmt>75712</DeferredCompensationFlngOrgAmt>
        <DeferredCompRltdOrgsAmt>11776</DeferredCompRltdOrgsAmt>
        <NontaxableBenefitsFilingOrgAmt>17985</NontaxableBenefitsFilingOrgAmt>
        <NontaxableBenefitsRltdOrgsAmt>2797</NontaxableBenefitsRltdOrgsAmt>
        <TotalCompensationFilingOrgAmt>331090</TotalCompensationFilingOrgAmt>
        <TotalCompensationRltdOrgsAmt>51496</TotalCompensationRltdOrgsAmt>
        <CompReportPrior990FilingOrgAmt>0</CompReportPrior990FilingOrgAmt>
        <CompReportPrior990RltdOrgsAmt>0</CompReportPrior990RltdOrgsAmt>
      </RltdOrgOfficerTrstKeyEmplGrp>
      <RltdOrgOfficerTrstKeyEmplGrp>
        <PersonNm>ANDREA OLARIU</PersonNm>
        <TitleTxt>CHIEF OPERATING OFFICER</TitleTxt>
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        <CompensationBasedOnRltdOrgsAmt>112884</CompensationBasedOnRltdOrgsAmt>
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        <BonusRelatedOrganizationsAmt>36843</BonusRelatedOrganizationsAmt>
        <OtherCompensationFilingOrgAmt>1240</OtherCompensationFilingOrgAmt>
        <OtherCompensationRltdOrgsAmt>520</OtherCompensationRltdOrgsAmt>
        <DeferredCompensationFlngOrgAmt>111474</DeferredCompensationFlngOrgAmt>
        <DeferredCompRltdOrgsAmt>46802</DeferredCompRltdOrgsAmt>
        <NontaxableBenefitsFilingOrgAmt>36949</NontaxableBenefitsFilingOrgAmt>
        <NontaxableBenefitsRltdOrgsAmt>15513</NontaxableBenefitsRltdOrgsAmt>
        <TotalCompensationFilingOrgAmt>506282</TotalCompensationFilingOrgAmt>
        <TotalCompensationRltdOrgsAmt>212562</TotalCompensationRltdOrgsAmt>
        <CompReportPrior990FilingOrgAmt>87752</CompReportPrior990FilingOrgAmt>
        <CompReportPrior990RltdOrgsAmt>36843</CompReportPrior990RltdOrgsAmt>
      </RltdOrgOfficerTrstKeyEmplGrp>
      <RltdOrgOfficerTrstKeyEmplGrp>
        <PersonNm>SALLY STEPHENS</PersonNm>
        <TitleTxt>CHIEF BUSINESS OFFICER</TitleTxt>
        <BaseCompensationFilingOrgAmt>321210</BaseCompensationFilingOrgAmt>
        <CompensationBasedOnRltdOrgsAmt>3146</CompensationBasedOnRltdOrgsAmt>
        <BonusFilingOrganizationAmount>101206</BonusFilingOrganizationAmount>
        <BonusRelatedOrganizationsAmt>991</BonusRelatedOrganizationsAmt>
        <OtherCompensationFilingOrgAmt>4904</OtherCompensationFilingOrgAmt>
        <OtherCompensationRltdOrgsAmt>48</OtherCompensationRltdOrgsAmt>
        <DeferredCompensationFlngOrgAmt>115699</DeferredCompensationFlngOrgAmt>
        <DeferredCompRltdOrgsAmt>1133</DeferredCompRltdOrgsAmt>
        <NontaxableBenefitsFilingOrgAmt>7927</NontaxableBenefitsFilingOrgAmt>
        <NontaxableBenefitsRltdOrgsAmt>78</NontaxableBenefitsRltdOrgsAmt>
        <TotalCompensationFilingOrgAmt>550946</TotalCompensationFilingOrgAmt>
        <TotalCompensationRltdOrgsAmt>5396</TotalCompensationRltdOrgsAmt>
        <CompReportPrior990FilingOrgAmt>101206</CompReportPrior990FilingOrgAmt>
        <CompReportPrior990RltdOrgsAmt>991</CompReportPrior990RltdOrgsAmt>
      </RltdOrgOfficerTrstKeyEmplGrp>
      <RltdOrgOfficerTrstKeyEmplGrp>
        <PersonNm>MARK BUSCH</PersonNm>
        <TitleTxt>VP, QUALITY ASSURANCE</TitleTxt>
        <BaseCompensationFilingOrgAmt>184181</BaseCompensationFilingOrgAmt>
        <CompensationBasedOnRltdOrgsAmt>82439</CompensationBasedOnRltdOrgsAmt>
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        <BonusRelatedOrganizationsAmt>22453</BonusRelatedOrganizationsAmt>
        <OtherCompensationFilingOrgAmt>5232</OtherCompensationFilingOrgAmt>
        <OtherCompensationRltdOrgsAmt>2342</OtherCompensationRltdOrgsAmt>
        <DeferredCompensationFlngOrgAmt>58777</DeferredCompensationFlngOrgAmt>
        <DeferredCompRltdOrgsAmt>26309</DeferredCompRltdOrgsAmt>
        <NontaxableBenefitsFilingOrgAmt>10540</NontaxableBenefitsFilingOrgAmt>
        <NontaxableBenefitsRltdOrgsAmt>4718</NontaxableBenefitsRltdOrgsAmt>
        <TotalCompensationFilingOrgAmt>308892</TotalCompensationFilingOrgAmt>
        <TotalCompensationRltdOrgsAmt>138261</TotalCompensationRltdOrgsAmt>
        <CompReportPrior990FilingOrgAmt>50162</CompReportPrior990FilingOrgAmt>
        <CompReportPrior990RltdOrgsAmt>22453</CompReportPrior990RltdOrgsAmt>
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      <RltdOrgOfficerTrstKeyEmplGrp>
        <PersonNm>ROBERT STARR</PersonNm>
        <TitleTxt>EXECUTIVE DIRECTOR, CLINICAL OPS &amp; M</TitleTxt>
        <BaseCompensationFilingOrgAmt>152744</BaseCompensationFilingOrgAmt>
        <CompensationBasedOnRltdOrgsAmt>77292</CompensationBasedOnRltdOrgsAmt>
        <BonusFilingOrganizationAmount>34475</BonusFilingOrganizationAmount>
        <BonusRelatedOrganizationsAmt>17445</BonusRelatedOrganizationsAmt>
        <OtherCompensationFilingOrgAmt>4131</OtherCompensationFilingOrgAmt>
        <OtherCompensationRltdOrgsAmt>2090</OtherCompensationRltdOrgsAmt>
        <DeferredCompensationFlngOrgAmt>42865</DeferredCompensationFlngOrgAmt>
        <DeferredCompRltdOrgsAmt>21691</DeferredCompRltdOrgsAmt>
        <NontaxableBenefitsFilingOrgAmt>11652</NontaxableBenefitsFilingOrgAmt>
        <NontaxableBenefitsRltdOrgsAmt>5896</NontaxableBenefitsRltdOrgsAmt>
        <TotalCompensationFilingOrgAmt>245867</TotalCompensationFilingOrgAmt>
        <TotalCompensationRltdOrgsAmt>124414</TotalCompensationRltdOrgsAmt>
        <CompReportPrior990FilingOrgAmt>34475</CompReportPrior990FilingOrgAmt>
        <CompReportPrior990RltdOrgsAmt>17445</CompReportPrior990RltdOrgsAmt>
      </RltdOrgOfficerTrstKeyEmplGrp>
      <RltdOrgOfficerTrstKeyEmplGrp>
        <PersonNm>ROBERT DECKMAN</PersonNm>
        <TitleTxt>VP, PRODUCT DEVELOPMENT</TitleTxt>
        <BaseCompensationFilingOrgAmt>223508</BaseCompensationFilingOrgAmt>
        <CompensationBasedOnRltdOrgsAmt>8155</CompensationBasedOnRltdOrgsAmt>
        <BonusFilingOrganizationAmount>51400</BonusFilingOrganizationAmount>
        <BonusRelatedOrganizationsAmt>1875</BonusRelatedOrganizationsAmt>
        <OtherCompensationFilingOrgAmt>1434</OtherCompensationFilingOrgAmt>
        <OtherCompensationRltdOrgsAmt>52</OtherCompensationRltdOrgsAmt>
        <DeferredCompensationFlngOrgAmt>74183</DeferredCompensationFlngOrgAmt>
        <DeferredCompRltdOrgsAmt>2707</DeferredCompRltdOrgsAmt>
        <NontaxableBenefitsFilingOrgAmt>44722</NontaxableBenefitsFilingOrgAmt>
        <NontaxableBenefitsRltdOrgsAmt>1632</NontaxableBenefitsRltdOrgsAmt>
        <TotalCompensationFilingOrgAmt>395247</TotalCompensationFilingOrgAmt>
        <TotalCompensationRltdOrgsAmt>14421</TotalCompensationRltdOrgsAmt>
        <CompReportPrior990FilingOrgAmt>51400</CompReportPrior990FilingOrgAmt>
        <CompReportPrior990RltdOrgsAmt>1875</CompReportPrior990RltdOrgsAmt>
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      <RltdOrgOfficerTrstKeyEmplGrp>
        <PersonNm>SUSAN MARTIN</PersonNm>
        <TitleTxt>VP, US COMMERCIAL BUSINESS</TitleTxt>
        <BaseCompensationFilingOrgAmt>229247</BaseCompensationFilingOrgAmt>
        <CompensationBasedOnRltdOrgsAmt>0</CompensationBasedOnRltdOrgsAmt>
        <BonusFilingOrganizationAmount>53100</BonusFilingOrganizationAmount>
        <BonusRelatedOrganizationsAmt>0</BonusRelatedOrganizationsAmt>
        <OtherCompensationFilingOrgAmt>1873</OtherCompensationFilingOrgAmt>
        <OtherCompensationRltdOrgsAmt>0</OtherCompensationRltdOrgsAmt>
        <DeferredCompensationFlngOrgAmt>64439</DeferredCompensationFlngOrgAmt>
        <DeferredCompRltdOrgsAmt>0</DeferredCompRltdOrgsAmt>
        <NontaxableBenefitsFilingOrgAmt>31879</NontaxableBenefitsFilingOrgAmt>
        <NontaxableBenefitsRltdOrgsAmt>0</NontaxableBenefitsRltdOrgsAmt>
        <TotalCompensationFilingOrgAmt>380538</TotalCompensationFilingOrgAmt>
        <TotalCompensationRltdOrgsAmt>0</TotalCompensationRltdOrgsAmt>
        <CompReportPrior990FilingOrgAmt>53100</CompReportPrior990FilingOrgAmt>
        <CompReportPrior990RltdOrgsAmt>0</CompReportPrior990RltdOrgsAmt>
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      <RltdOrgOfficerTrstKeyEmplGrp>
        <PersonNm>AUTUMN EHNOW</PersonNm>
        <TitleTxt>VP, PUBLIC POLICY &amp; GOVERNMENT AFFAI</TitleTxt>
        <BaseCompensationFilingOrgAmt>179911</BaseCompensationFilingOrgAmt>
        <CompensationBasedOnRltdOrgsAmt>0</CompensationBasedOnRltdOrgsAmt>
        <BonusFilingOrganizationAmount>66450</BonusFilingOrganizationAmount>
        <BonusRelatedOrganizationsAmt>0</BonusRelatedOrganizationsAmt>
        <OtherCompensationFilingOrgAmt>869</OtherCompensationFilingOrgAmt>
        <OtherCompensationRltdOrgsAmt>0</OtherCompensationRltdOrgsAmt>
        <DeferredCompensationFlngOrgAmt>59360</DeferredCompensationFlngOrgAmt>
        <DeferredCompRltdOrgsAmt>0</DeferredCompRltdOrgsAmt>
        <NontaxableBenefitsFilingOrgAmt>29872</NontaxableBenefitsFilingOrgAmt>
        <NontaxableBenefitsRltdOrgsAmt>0</NontaxableBenefitsRltdOrgsAmt>
        <TotalCompensationFilingOrgAmt>336462</TotalCompensationFilingOrgAmt>
        <TotalCompensationRltdOrgsAmt>0</TotalCompensationRltdOrgsAmt>
        <CompReportPrior990FilingOrgAmt>66450</CompReportPrior990FilingOrgAmt>
        <CompReportPrior990RltdOrgsAmt>0</CompReportPrior990RltdOrgsAmt>
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      <SupplementalInformationDetail>
        <FormAndLineReferenceDesc>PART I, LINE 1A</FormAndLineReferenceDesc>
        <ExplanationTxt>MEDICINES360 MADE GROSS-UP PAYMENTS FOR AIRLINE AWARDS STATUS FOR CERTAIN EXECUTIVE-LEVEL EMPLOYEES.</ExplanationTxt>
      </SupplementalInformationDetail>
      <SupplementalInformationDetail>
        <FormAndLineReferenceDesc>PART I, LINE 1B</FormAndLineReferenceDesc>
        <ExplanationTxt>MEDICINES360 DOES NOT HAVE A WRITTEN POLICY FOR GROSS-UP PAYMENTS.</ExplanationTxt>
      </SupplementalInformationDetail>
      <SupplementalInformationDetail>
        <FormAndLineReferenceDesc>PART I, LINE 7</FormAndLineReferenceDesc>
        <ExplanationTxt>EMPLOYEES OF MEDICINES360 RECEIVED DISCRETIONARY BONUSES THAT WERE DETERMINED AND APPROVED BY THE BOARD OF DIRECTORS.</ExplanationTxt>
      </SupplementalInformationDetail>
    </IRS990ScheduleJ>
    <IRS990ScheduleO documentId="RetDoc1044400001">
      <SupplementalInformationDetail>
        <FormAndLineReferenceDesc>FORM 990, PART VI, SECTION B, LINE 11B</FormAndLineReferenceDesc>
        <ExplanationTxt>BEFORE FILING, THE TAX RETURN IS PROVIDED TO THE BOARD AUDIT COMMITTEE FOR THEIR REVIEW AND APPROVAL, AND THE FULL BOARD FOR THEIR REVIEW.</ExplanationTxt>
      </SupplementalInformationDetail>
      <SupplementalInformationDetail>
        <FormAndLineReferenceDesc>FORM 990, PART VI, SECTION B, LINE 12C</FormAndLineReferenceDesc>
        <ExplanationTxt>OFFICERS/DIRECTORS ARE REQUIRED TO DISCLOSE OR UPDATE ANNUALLY INTERESTS THAT COULD GIVE RISE TO CONFLICTS OF INTEREST.</ExplanationTxt>
      </SupplementalInformationDetail>
      <SupplementalInformationDetail>
        <FormAndLineReferenceDesc>FORM 990, PART VI, SECTION B, LINE 15</FormAndLineReferenceDesc>
        <ExplanationTxt>THE CEO COMPENSATION IS SET ON THE BASIS OF SALARY RANGES FOR COMPARABLY SIZED COMPANIES IN THE RADFORD GLOBAL LIFE SCIENCES SURVEY DATA AND COMPARABLE NON-PROFITS. THE COMPENSATION OF OFFICERS AND KEY EMPLOYEES ARE BENCH-MARKED AGAINST THE RADFORD GLOBAL LIFE SCIENCES SURVEY DATA AND COMPARABLE NON-PROFITS. THE BOARD OF DIRECTORS REVIEWS AND APPROVES THE DATA AND COMPENSATION FOR THE CEO. THE COMPENSATION OF OFFICERS IS REVIEWED AND APPROVED BY THE COMPENSATION COMMITTEE, WHICH IS COMPRISED OF INDEPENDENT BOARD MEMBERS.</ExplanationTxt>
      </SupplementalInformationDetail>
      <SupplementalInformationDetail>
        <FormAndLineReferenceDesc>FORM 990, PART VI, SECTION C, LINE 19</FormAndLineReferenceDesc>
        <ExplanationTxt>DOCUMENTS ARE MADE AVAILABLE UPON REQUEST.</ExplanationTxt>
      </SupplementalInformationDetail>
      <SupplementalInformationDetail>
        <FormAndLineReferenceDesc>FORM 990, PART IX, LINE 11G</FormAndLineReferenceDesc>
        <ExplanationTxt>CONSULTANTS AND OUTSIDE SERVICES: PROGRAM SERVICE EXPENSES 1,945,179. MANAGEMENT AND GENERAL EXPENSES 535,072. FUNDRAISING EXPENSES 10,018. TOTAL EXPENSES 2,490,269. INTERCOMPANY SERVICE FEES: PROGRAM SERVICE EXPENSES 2,664,326. MANAGEMENT AND GENERAL EXPENSES 0. FUNDRAISING EXPENSES 0. TOTAL EXPENSES 2,664,326. CLINICAL TRIAL SUPPORT: PROGRAM SERVICE EXPENSES 1,668,048. MANAGEMENT AND GENERAL EXPENSES 0. FUNDRAISING EXPENSES 0. TOTAL EXPENSES 1,668,048. ENGINEERING SUPPORT: PROGRAM SERVICE EXPENSES 669,388. MANAGEMENT AND GENERAL EXPENSES 0. FUNDRAISING EXPENSES 0. TOTAL EXPENSES 669,388.</ExplanationTxt>
      </SupplementalInformationDetail>
      <SupplementalInformationDetail>
        <FormAndLineReferenceDesc>FORM 990, PART XI, LINE 9:</FormAndLineReferenceDesc>
        <ExplanationTxt>RETURN OF UNSPENT PRIOR YEAR GRANT FUNDS -620,725.</ExplanationTxt>
      </SupplementalInformationDetail>
    </IRS990ScheduleO>
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          <BusinessNameLine1Txt>IMPACT RH360 LLC</BusinessNameLine1Txt>
        </DisregardedEntityName>
        <USAddress>
          <AddressLine1Txt>353 SACRAMENTO STREET SUITE 300</AddressLine1Txt>
          <CityNm>SAN FRANCISCO</CityNm>
          <StateAbbreviationCd>CA</StateAbbreviationCd>
          <ZIPCd>94111</ZIPCd>
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        <LegalDomicileStateCd>CA</LegalDomicileStateCd>
        <DirectControllingEntityName>
          <BusinessNameLine1Txt>MEDICINES360</BusinessNameLine1Txt>
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        <EntityTypeTxt>C</EntityTypeTxt>
        <ShareOfTotalIncomeAmt>6664405</ShareOfTotalIncomeAmt>
        <ShareOfEOYAssetsAmt>4481290</ShareOfEOYAssetsAmt>
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      <GiftGrntCapContriFromOthOrgInd>0</GiftGrntCapContriFromOthOrgInd>
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      <LoansOrGuaranteesFromOthOrgInd>1</LoansOrGuaranteesFromOthOrgInd>
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      <AssetSaleToOtherOrgInd>0</AssetSaleToOtherOrgInd>
      <AssetPurchaseFromOtherOrgInd>0</AssetPurchaseFromOtherOrgInd>
      <AssetExchangeInd>0</AssetExchangeInd>
      <RentalOfFacilitiesToOthOrgInd>0</RentalOfFacilitiesToOthOrgInd>
      <RentalOfFcltsFromOthOrgInd>0</RentalOfFcltsFromOthOrgInd>
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      <TransactionsRelatedOrgGrp>
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          <BusinessNameLine1Txt>ALLIANCE PARTNERS360 INC</BusinessNameLine1Txt>
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        <MethodOfAmountDeterminationTxt>ACTUAL</MethodOfAmountDeterminationTxt>
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      <TransactionsRelatedOrgGrp>
        <OtherOrganizationName>
          <BusinessNameLine1Txt>ALLIANCE PARTNERS360 INC</BusinessNameLine1Txt>
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      <TransactionsRelatedOrgGrp>
        <OtherOrganizationName>
          <BusinessNameLine1Txt>ALLIANCE PARTNERS360 INC</BusinessNameLine1Txt>
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        <TransactionTypeTxt>N</TransactionTypeTxt>
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        <MethodOfAmountDeterminationTxt>ACTUAL</MethodOfAmountDeterminationTxt>
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      <TransactionsRelatedOrgGrp>
        <OtherOrganizationName>
          <BusinessNameLine1Txt>ALLIANCE PARTNERS360 INC</BusinessNameLine1Txt>
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        <MethodOfAmountDeterminationTxt>ACTUAL</MethodOfAmountDeterminationTxt>
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</Return>