﻿<?xml version="1.0" encoding="utf-8"?>
<Return xmlns="http://www.irs.gov/efile" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" returnVersion="2018v3.1">
  <ReturnHeader binaryAttachmentCnt="0">
    <ReturnTs>2019-11-14T13:52:34-06:00</ReturnTs>
    <TaxPeriodEndDt>2018-12-31</TaxPeriodEndDt>
    <PreparerFirmGrp>
      <PreparerFirmEIN>631262841</PreparerFirmEIN>
      <PreparerFirmName>
        <BusinessNameLine1Txt>ANGLIN REICHMANN ARMSTRONG PC</BusinessNameLine1Txt>
      </PreparerFirmName>
      <PreparerUSAddress>
        <AddressLine1Txt>305 QUALITY CIRCLE</AddressLine1Txt>
        <CityNm>HUNTSVILLE</CityNm>
        <StateAbbreviationCd>AL</StateAbbreviationCd>
        <ZIPCd>358065539</ZIPCd>
      </PreparerUSAddress>
    </PreparerFirmGrp>
    <ReturnTypeCd>990</ReturnTypeCd>
    <TaxPeriodBeginDt>2018-01-01</TaxPeriodBeginDt>
    <Filer>
      <EIN>432059317</EIN>
      <BusinessName>
        <BusinessNameLine1Txt>HUDSON-ALPHA INSTITUTE FOR</BusinessNameLine1Txt>
        <BusinessNameLine2Txt>BIOTECHNOLOGY</BusinessNameLine2Txt>
      </BusinessName>
      <BusinessNameControlTxt>HUDS</BusinessNameControlTxt>
      <PhoneNum>2563270400</PhoneNum>
      <USAddress>
        <AddressLine1Txt>601 GENOME WAY</AddressLine1Txt>
        <CityNm>HUNTSVILLE</CityNm>
        <StateAbbreviationCd>AL</StateAbbreviationCd>
        <ZIPCd>35806</ZIPCd>
      </USAddress>
    </Filer>
    <BusinessOfficerGrp>
      <PersonNm>PETER YANUL</PersonNm>
      <PersonTitleTxt>CFO</PersonTitleTxt>
      <PhoneNum>2563270400</PhoneNum>
      <SignatureDt>2019-11-14</SignatureDt>
      <DiscussWithPaidPreparerInd>true</DiscussWithPaidPreparerInd>
    </BusinessOfficerGrp>
    <PreparerPersonGrp>
      <PreparerPersonNm>TRACY L SAMS CPA</PreparerPersonNm>
      <PTIN>P00637535</PTIN>
      <PhoneNum>2565331040</PhoneNum>
      <PreparationDt>2019-11-14</PreparationDt>
    </PreparerPersonGrp>
    <FilingSecurityInformation>
      <IPAddress>
        <IPv4AddressTxt>12.203.77.243</IPv4AddressTxt>
      </IPAddress>
      <IPDt>2019-11-14</IPDt>
      <IPTm>13:52:34</IPTm>
      <IPTimezoneCd>CS</IPTimezoneCd>
      <FilingLicenseTypeCd>P</FilingLicenseTypeCd>
      <AtSubmissionCreationDeviceId>0A5D44E7604C93DAE01D087995CF0C30D31FED62</AtSubmissionCreationDeviceId>
      <AtSubmissionFilingDeviceId>DBD2B521F885AE5A17C913DBC8323D7E1CD557DE</AtSubmissionFilingDeviceId>
    </FilingSecurityInformation>
    <TaxYr>2018</TaxYr>
    <BuildTS>2020-03-31 21:24:44Z</BuildTS>
  </ReturnHeader>
  <ReturnData documentCnt="9">
    <IRS990 documentId="RetDoc2" referenceDocumentId="RetDoc7">
      <PrincipalOfficerNm>RICHARD MYERS</PrincipalOfficerNm>
      <USAddress>
        <AddressLine1Txt>601 GENOME WAY</AddressLine1Txt>
        <CityNm>HUNTSVILLE</CityNm>
        <StateAbbreviationCd>AL</StateAbbreviationCd>
        <ZIPCd>35806</ZIPCd>
      </USAddress>
      <GrossReceiptsAmt>83579818</GrossReceiptsAmt>
      <GroupReturnForAffiliatesInd>false</GroupReturnForAffiliatesInd>
      <Organization501c3Ind>X</Organization501c3Ind>
      <WebsiteAddressTxt>WWW.HUDSONALPHA.ORG</WebsiteAddressTxt>
      <TypeOfOrganizationCorpInd>X</TypeOfOrganizationCorpInd>
      <FormationYr>2004</FormationYr>
      <LegalDomicileStateCd>AL</LegalDomicileStateCd>
      <ActivityOrMissionDesc>THE PRIMARY MISSION OF THE INSTITUTE WILL BE TO USE THE INCREASINGLY POWERFUL RESEARCH TOOLS BEING DEVELOPED IN THE BIOTECHNOLOGY AREA TO BETTER UNDERSTAND THE CAUSES OF CERTAIN DISEASES AND TO APPLY THE FINDINGS OF SUCH RESEARCH TO HELP DEVELOP NEW AND MORE EFFECTIVE TREATMENTS FOR SUCH DISEASES. THE INSTITUTE'S CHARITABLE MISSION CONTEMPLATES NUMEROUS OTHER ACTIVITIES ALL OF WHICH ARE INTENDED TO HELP FURTHER BIOTECH RESEARCH IN ALABAMA.</ActivityOrMissionDesc>
      <VotingMembersGoverningBodyCnt>11</VotingMembersGoverningBodyCnt>
      <VotingMembersIndependentCnt>11</VotingMembersIndependentCnt>
      <TotalEmployeeCnt>238</TotalEmployeeCnt>
      <TotalVolunteersCnt>50</TotalVolunteersCnt>
      <TotalGrossUBIAmt>0</TotalGrossUBIAmt>
      <PYContributionsGrantsAmt>23581451</PYContributionsGrantsAmt>
      <CYContributionsGrantsAmt>45424175</CYContributionsGrantsAmt>
      <PYProgramServiceRevenueAmt>25001290</PYProgramServiceRevenueAmt>
      <CYProgramServiceRevenueAmt>31749111</CYProgramServiceRevenueAmt>
      <PYInvestmentIncomeAmt>132291</PYInvestmentIncomeAmt>
      <CYInvestmentIncomeAmt>1167125</CYInvestmentIncomeAmt>
      <PYOtherRevenueAmt>2562838</PYOtherRevenueAmt>
      <CYOtherRevenueAmt>2328145</CYOtherRevenueAmt>
      <PYTotalRevenueAmt>51277870</PYTotalRevenueAmt>
      <CYTotalRevenueAmt>80668556</CYTotalRevenueAmt>
      <CYGrantsAndSimilarPaidAmt>0</CYGrantsAndSimilarPaidAmt>
      <CYBenefitsPaidToMembersAmt>0</CYBenefitsPaidToMembersAmt>
      <PYSalariesCompEmpBnftPaidAmt>12478070</PYSalariesCompEmpBnftPaidAmt>
      <CYSalariesCompEmpBnftPaidAmt>11903381</CYSalariesCompEmpBnftPaidAmt>
      <PYTotalProfFndrsngExpnsAmt>136683</PYTotalProfFndrsngExpnsAmt>
      <CYTotalProfFndrsngExpnsAmt>116375</CYTotalProfFndrsngExpnsAmt>
      <CYTotalFundraisingExpenseAmt>619251</CYTotalFundraisingExpenseAmt>
      <PYOtherExpensesAmt>49388678</PYOtherExpensesAmt>
      <CYOtherExpensesAmt>59712369</CYOtherExpensesAmt>
      <PYTotalExpensesAmt>62003431</PYTotalExpensesAmt>
      <CYTotalExpensesAmt>71732125</CYTotalExpensesAmt>
      <PYRevenuesLessExpensesAmt>-10725561</PYRevenuesLessExpensesAmt>
      <CYRevenuesLessExpensesAmt>8936431</CYRevenuesLessExpensesAmt>
      <TotalAssetsBOYAmt>117385988</TotalAssetsBOYAmt>
      <TotalAssetsEOYAmt>123524115</TotalAssetsEOYAmt>
      <TotalLiabilitiesBOYAmt>22649092</TotalLiabilitiesBOYAmt>
      <TotalLiabilitiesEOYAmt>20010141</TotalLiabilitiesEOYAmt>
      <NetAssetsOrFundBalancesBOYAmt>94736896</NetAssetsOrFundBalancesBOYAmt>
      <NetAssetsOrFundBalancesEOYAmt>103513974</NetAssetsOrFundBalancesEOYAmt>
      <InfoInScheduleOPartIIIInd>X</InfoInScheduleOPartIIIInd>
      <MissionDesc>THE PRIMARY MISSION OF THE INSTITUTE WILL BE TO USE THE INCREASINGLY POWERFUL RESEARCH TOOLS BEING DEVELOPED IN THE BIOTECHNOLOGY AREA TO BETTER UNDERSTAND THE CAUSES OF CERTAIN DISEASES AND TO APPLY THE FINDINGS OF SUCH RESEARCH TO HELP DEVELOP NEW AND MORE EFFECTIVE TREATMENTS FOR SUCH DISEASES. THE INSTITUTE'S CHARITABLE MISSION CONTEMPLATES NUMEROUS OTHER ACTIVITIES ALL OF WHICH ARE INTENDED TO HELP FURTHER BIOTECH RESEARCH IN ALABAMA.</MissionDesc>
      <SignificantNewProgramSrvcInd>false</SignificantNewProgramSrvcInd>
      <SignificantChangeInd>false</SignificantChangeInd>
      <ExpenseAmt>48078024</ExpenseAmt>
      <Desc>ACTIVITIES, PROGRAMS, AND COLLABORATIONS FOR THE INSTITUTE TO ACCOMPLISH ITS CHARITABLE OBJECTIVE OF SERVING AS A CATALYST FOR BIOTECHNOLOGY RESEARCH AND DEVELOPEMENT.</Desc>
      <ProgSrvcAccomActy2Grp>
        <ExpenseAmt>1412603</ExpenseAmt>
        <Desc>ACTIVITIES, PROGRAMS AND COLLABORATIONS FOR THE INSTITUTE TO ACCOMPLISH ITS CHARITABLE OBJECTIVE OF PROVIDING A VARIETY OF EDUCATIONAL OUTREACH PROGRAMS.</Desc>
      </ProgSrvcAccomActy2Grp>
      <ProgSrvcAccomActy3Grp>
        <ExpenseAmt>1597590</ExpenseAmt>
        <Desc>ACTIVITIES, PROGRAMS AND COLLABORATIONS FOR THE INSTITUTE TO ACCOMPLISH ITS CHARITABLE OBJECTIVE OF DEVELOPING, PROVIDING AND ADVANCING GENOMIC MEDICINE PROGRAMS.</Desc>
      </ProgSrvcAccomActy3Grp>
      <TotalProgramServiceExpensesAmt>51088217</TotalProgramServiceExpensesAmt>
      <DescribedInSection501c3Ind referenceDocumentId="RetDoc9">true</DescribedInSection501c3Ind>
      <ScheduleBRequiredInd referenceDocumentId="RetDoc1">true</ScheduleBRequiredInd>
      <PoliticalCampaignActyInd referenceDocumentId="RetDoc3">false</PoliticalCampaignActyInd>
      <LobbyingActivitiesInd referenceDocumentId="RetDoc3">true</LobbyingActivitiesInd>
      <SubjectToProxyTaxInd referenceDocumentId="RetDoc3">false</SubjectToProxyTaxInd>
      <DonorAdvisedFundInd referenceDocumentId="RetDoc4">false</DonorAdvisedFundInd>
      <ConservationEasementsInd referenceDocumentId="RetDoc4">false</ConservationEasementsInd>
      <CollectionsOfArtInd referenceDocumentId="RetDoc4">false</CollectionsOfArtInd>
      <CreditCounselingInd referenceDocumentId="RetDoc4">false</CreditCounselingInd>
      <TempOrPermanentEndowmentsInd referenceDocumentId="RetDoc4">true</TempOrPermanentEndowmentsInd>
      <ReportLandBuildingEquipmentInd referenceDocumentId="RetDoc4">true</ReportLandBuildingEquipmentInd>
      <ReportInvestmentsOtherSecInd referenceDocumentId="RetDoc4">false</ReportInvestmentsOtherSecInd>
      <ReportProgramRelatedInvstInd referenceDocumentId="RetDoc4">false</ReportProgramRelatedInvstInd>
      <ReportOtherAssetsInd referenceDocumentId="RetDoc4">false</ReportOtherAssetsInd>
      <ReportOtherLiabilitiesInd referenceDocumentId="RetDoc4">true</ReportOtherLiabilitiesInd>
      <IncludeFIN48FootnoteInd referenceDocumentId="RetDoc4">false</IncludeFIN48FootnoteInd>
      <IndependentAuditFinclStmtInd referenceDocumentId="RetDoc4">false</IndependentAuditFinclStmtInd>
      <ConsolidatedAuditFinclStmtInd referenceDocumentId="RetDoc4">true</ConsolidatedAuditFinclStmtInd>
      <SchoolOperatingInd>false</SchoolOperatingInd>
      <ForeignOfficeInd>false</ForeignOfficeInd>
      <ForeignActivitiesInd>false</ForeignActivitiesInd>
      <MoreThan5000KToOrgInd>false</MoreThan5000KToOrgInd>
      <MoreThan5000KToIndividualsInd>false</MoreThan5000KToIndividualsInd>
      <ProfessionalFundraisingInd referenceDocumentId="RetDoc5">true</ProfessionalFundraisingInd>
      <FundraisingActivitiesInd referenceDocumentId="RetDoc5">false</FundraisingActivitiesInd>
      <GamingActivitiesInd referenceDocumentId="RetDoc5">false</GamingActivitiesInd>
      <OperateHospitalInd>false</OperateHospitalInd>
      <GrantsToOrganizationsInd>false</GrantsToOrganizationsInd>
      <GrantsToIndividualsInd>false</GrantsToIndividualsInd>
      <ScheduleJRequiredInd referenceDocumentId="RetDoc6">true</ScheduleJRequiredInd>
      <TaxExemptBondsInd>false</TaxExemptBondsInd>
      <EngagedInExcessBenefitTransInd>false</EngagedInExcessBenefitTransInd>
      <PYExcessBenefitTransInd>false</PYExcessBenefitTransInd>
      <LoanOutstandingInd>false</LoanOutstandingInd>
      <GrantToRelatedPersonInd>false</GrantToRelatedPersonInd>
      <BusinessRlnWithOrgMemInd>false</BusinessRlnWithOrgMemInd>
      <BusinessRlnWithFamMemInd>false</BusinessRlnWithFamMemInd>
      <BusinessRlnWithOfficerEntInd>false</BusinessRlnWithOfficerEntInd>
      <DeductibleNonCashContriInd>false</DeductibleNonCashContriInd>
      <DeductibleArtContributionInd>false</DeductibleArtContributionInd>
      <TerminateOperationsInd>false</TerminateOperationsInd>
      <PartialLiquidationInd>false</PartialLiquidationInd>
      <DisregardedEntityInd referenceDocumentId="RetDoc8">true</DisregardedEntityInd>
      <RelatedEntityInd referenceDocumentId="RetDoc8">true</RelatedEntityInd>
      <RelatedOrganizationCtrlEntInd>false</RelatedOrganizationCtrlEntInd>
      <TrnsfrExmptNonChrtblRltdOrgInd referenceDocumentId="RetDoc8">false</TrnsfrExmptNonChrtblRltdOrgInd>
      <ActivitiesConductedPrtshpInd referenceDocumentId="RetDoc8">false</ActivitiesConductedPrtshpInd>
      <ScheduleORequiredInd>true</ScheduleORequiredInd>
      <IRPDocumentCnt>125</IRPDocumentCnt>
      <IRPDocumentW2GCnt>0</IRPDocumentW2GCnt>
      <BackupWthldComplianceInd>true</BackupWthldComplianceInd>
      <EmployeeCnt>238</EmployeeCnt>
      <EmploymentTaxReturnsFiledInd>true</EmploymentTaxReturnsFiledInd>
      <UnrelatedBusIncmOverLimitInd>false</UnrelatedBusIncmOverLimitInd>
      <ForeignFinancialAccountInd>false</ForeignFinancialAccountInd>
      <ProhibitedTaxShelterTransInd>false</ProhibitedTaxShelterTransInd>
      <TaxablePartyNotificationInd>false</TaxablePartyNotificationInd>
      <NondeductibleContributionsInd>false</NondeductibleContributionsInd>
      <IndoorTanningServicesInd>false</IndoorTanningServicesInd>
      <SubjToTaxRmnrtnExPrchtPymtInd>false</SubjToTaxRmnrtnExPrchtPymtInd>
      <SubjectToExcsTaxNetInvstIncInd>false</SubjectToExcsTaxNetInvstIncInd>
      <InfoInScheduleOPartVIInd>X</InfoInScheduleOPartVIInd>
      <GoverningBodyVotingMembersCnt>11</GoverningBodyVotingMembersCnt>
      <IndependentVotingMemberCnt>11</IndependentVotingMemberCnt>
      <FamilyOrBusinessRlnInd>false</FamilyOrBusinessRlnInd>
      <DelegationOfMgmtDutiesInd>false</DelegationOfMgmtDutiesInd>
      <ChangeToOrgDocumentsInd>false</ChangeToOrgDocumentsInd>
      <MaterialDiversionOrMisuseInd>false</MaterialDiversionOrMisuseInd>
      <MembersOrStockholdersInd>false</MembersOrStockholdersInd>
      <ElectionOfBoardMembersInd>false</ElectionOfBoardMembersInd>
      <DecisionsSubjectToApprovaInd>false</DecisionsSubjectToApprovaInd>
      <MinutesOfGoverningBodyInd>true</MinutesOfGoverningBodyInd>
      <MinutesOfCommitteesInd>true</MinutesOfCommitteesInd>
      <OfficerMailingAddressInd>false</OfficerMailingAddressInd>
      <LocalChaptersInd>false</LocalChaptersInd>
      <Form990ProvidedToGvrnBodyInd>true</Form990ProvidedToGvrnBodyInd>
      <ConflictOfInterestPolicyInd>true</ConflictOfInterestPolicyInd>
      <AnnualDisclosureCoveredPrsnInd>true</AnnualDisclosureCoveredPrsnInd>
      <RegularMonitoringEnfrcInd>true</RegularMonitoringEnfrcInd>
      <WhistleblowerPolicyInd>true</WhistleblowerPolicyInd>
      <DocumentRetentionPolicyInd>false</DocumentRetentionPolicyInd>
      <CompensationProcessCEOInd>false</CompensationProcessCEOInd>
      <CompensationProcessOtherInd>false</CompensationProcessOtherInd>
      <InvestmentInJointVentureInd>true</InvestmentInJointVentureInd>
      <WrittenPolicyOrProcedureInd>true</WrittenPolicyOrProcedureInd>
      <UponRequestInd>X</UponRequestInd>
      <BooksInCareOfDetail>
        <PersonNm>PETE YANUL</PersonNm>
        <PhoneNum>2563270400</PhoneNum>
        <USAddress>
          <AddressLine1Txt>601 GENOME WAY</AddressLine1Txt>
          <CityNm>HUNTSVILLE</CityNm>
          <StateAbbreviationCd>AL</StateAbbreviationCd>
          <ZIPCd>35806</ZIPCd>
        </USAddress>
      </BooksInCareOfDetail>
      <Form990PartVIISectionAGrp>
        <PersonNm>A EUGENE SAPP</PersonNm>
        <TitleTxt>DIRECTOR</TitleTxt>
        <AverageHoursPerWeekRt>1.00</AverageHoursPerWeekRt>
        <IndividualTrusteeOrDirectorInd>X</IndividualTrusteeOrDirectorInd>
        <ReportableCompFromOrgAmt>0</ReportableCompFromOrgAmt>
        <ReportableCompFromRltdOrgAmt>0</ReportableCompFromRltdOrgAmt>
        <OtherCompensationAmt>0</OtherCompensationAmt>
      </Form990PartVIISectionAGrp>
      <Form990PartVIISectionAGrp>
        <PersonNm>DANNY WINDHAM</PersonNm>
        <TitleTxt>DIRECTOR</TitleTxt>
        <AverageHoursPerWeekRt>1.00</AverageHoursPerWeekRt>
        <IndividualTrusteeOrDirectorInd>X</IndividualTrusteeOrDirectorInd>
        <ReportableCompFromOrgAmt>0</ReportableCompFromOrgAmt>
        <ReportableCompFromRltdOrgAmt>0</ReportableCompFromRltdOrgAmt>
        <OtherCompensationAmt>0</OtherCompensationAmt>
      </Form990PartVIISectionAGrp>
      <Form990PartVIISectionAGrp>
        <PersonNm>J MILTON HARRIS</PersonNm>
        <TitleTxt>DIRECTOR</TitleTxt>
        <AverageHoursPerWeekRt>1.00</AverageHoursPerWeekRt>
        <IndividualTrusteeOrDirectorInd>X</IndividualTrusteeOrDirectorInd>
        <ReportableCompFromOrgAmt>0</ReportableCompFromOrgAmt>
        <ReportableCompFromRltdOrgAmt>0</ReportableCompFromRltdOrgAmt>
        <OtherCompensationAmt>0</OtherCompensationAmt>
      </Form990PartVIISectionAGrp>
      <Form990PartVIISectionAGrp>
        <PersonNm>JAMES R HUDSON JR</PersonNm>
        <TitleTxt>DIR/CHAIRMAN</TitleTxt>
        <AverageHoursPerWeekRt>1.00</AverageHoursPerWeekRt>
        <IndividualTrusteeOrDirectorInd>X</IndividualTrusteeOrDirectorInd>
        <ReportableCompFromOrgAmt>0</ReportableCompFromOrgAmt>
        <ReportableCompFromRltdOrgAmt>0</ReportableCompFromRltdOrgAmt>
        <OtherCompensationAmt>0</OtherCompensationAmt>
      </Form990PartVIISectionAGrp>
      <Form990PartVIISectionAGrp>
        <PersonNm>JOHN R WYNN</PersonNm>
        <TitleTxt>SECRETARY</TitleTxt>
        <AverageHoursPerWeekRt>1.00</AverageHoursPerWeekRt>
        <IndividualTrusteeOrDirectorInd>X</IndividualTrusteeOrDirectorInd>
        <ReportableCompFromOrgAmt>0</ReportableCompFromOrgAmt>
        <ReportableCompFromRltdOrgAmt>0</ReportableCompFromRltdOrgAmt>
        <OtherCompensationAmt>0</OtherCompensationAmt>
      </Form990PartVIISectionAGrp>
      <Form990PartVIISectionAGrp>
        <PersonNm>SAMUEL P MCMANUS</PersonNm>
        <TitleTxt>DIRECTOR</TitleTxt>
        <AverageHoursPerWeekRt>1.00</AverageHoursPerWeekRt>
        <IndividualTrusteeOrDirectorInd>X</IndividualTrusteeOrDirectorInd>
        <ReportableCompFromOrgAmt>0</ReportableCompFromOrgAmt>
        <ReportableCompFromRltdOrgAmt>0</ReportableCompFromRltdOrgAmt>
        <OtherCompensationAmt>0</OtherCompensationAmt>
      </Form990PartVIISectionAGrp>
      <Form990PartVIISectionAGrp>
        <PersonNm>IRMA TUDER</PersonNm>
        <TitleTxt>DIRECTOR</TitleTxt>
        <AverageHoursPerWeekRt>1.00</AverageHoursPerWeekRt>
        <IndividualTrusteeOrDirectorInd>X</IndividualTrusteeOrDirectorInd>
        <ReportableCompFromOrgAmt>0</ReportableCompFromOrgAmt>
        <ReportableCompFromRltdOrgAmt>0</ReportableCompFromRltdOrgAmt>
        <OtherCompensationAmt>0</OtherCompensationAmt>
      </Form990PartVIISectionAGrp>
      <Form990PartVIISectionAGrp>
        <PersonNm>LINDA SMITH</PersonNm>
        <TitleTxt>DIRECTOR</TitleTxt>
        <AverageHoursPerWeekRt>1.00</AverageHoursPerWeekRt>
        <IndividualTrusteeOrDirectorInd>X</IndividualTrusteeOrDirectorInd>
        <ReportableCompFromOrgAmt>0</ReportableCompFromOrgAmt>
        <ReportableCompFromRltdOrgAmt>0</ReportableCompFromRltdOrgAmt>
        <OtherCompensationAmt>0</OtherCompensationAmt>
      </Form990PartVIISectionAGrp>
      <Form990PartVIISectionAGrp>
        <PersonNm>BARBARA FISK</PersonNm>
        <TitleTxt>DIRECTOR</TitleTxt>
        <AverageHoursPerWeekRt>1.00</AverageHoursPerWeekRt>
        <IndividualTrusteeOrDirectorInd>X</IndividualTrusteeOrDirectorInd>
        <ReportableCompFromOrgAmt>0</ReportableCompFromOrgAmt>
        <ReportableCompFromRltdOrgAmt>0</ReportableCompFromRltdOrgAmt>
        <OtherCompensationAmt>0</OtherCompensationAmt>
      </Form990PartVIISectionAGrp>
      <Form990PartVIISectionAGrp>
        <PersonNm>BOB RILEY</PersonNm>
        <TitleTxt>DIRECTOR</TitleTxt>
        <AverageHoursPerWeekRt>1.00</AverageHoursPerWeekRt>
        <IndividualTrusteeOrDirectorInd>X</IndividualTrusteeOrDirectorInd>
        <ReportableCompFromOrgAmt>0</ReportableCompFromOrgAmt>
        <ReportableCompFromRltdOrgAmt>0</ReportableCompFromRltdOrgAmt>
        <OtherCompensationAmt>0</OtherCompensationAmt>
      </Form990PartVIISectionAGrp>
      <Form990PartVIISectionAGrp>
        <PersonNm>BRIAN POLLOCK</PersonNm>
        <TitleTxt>DIRECTOR</TitleTxt>
        <AverageHoursPerWeekRt>1.00</AverageHoursPerWeekRt>
        <IndividualTrusteeOrDirectorInd>X</IndividualTrusteeOrDirectorInd>
        <ReportableCompFromOrgAmt>0</ReportableCompFromOrgAmt>
        <ReportableCompFromRltdOrgAmt>0</ReportableCompFromRltdOrgAmt>
        <OtherCompensationAmt>0</OtherCompensationAmt>
      </Form990PartVIISectionAGrp>
      <Form990PartVIISectionAGrp>
        <PersonNm>RICHARD MYERS</PersonNm>
        <TitleTxt>PRESIDENT</TitleTxt>
        <AverageHoursPerWeekRt>40.00</AverageHoursPerWeekRt>
        <OfficerInd>X</OfficerInd>
        <ReportableCompFromOrgAmt>693225</ReportableCompFromOrgAmt>
        <ReportableCompFromRltdOrgAmt>0</ReportableCompFromRltdOrgAmt>
        <OtherCompensationAmt>32600</OtherCompensationAmt>
      </Form990PartVIISectionAGrp>
      <Form990PartVIISectionAGrp>
        <PersonNm>CARTER WELLS</PersonNm>
        <TitleTxt>VP ECON DEVE</TitleTxt>
        <AverageHoursPerWeekRt>40.00</AverageHoursPerWeekRt>
        <OfficerInd>X</OfficerInd>
        <ReportableCompFromOrgAmt>250000</ReportableCompFromOrgAmt>
        <ReportableCompFromRltdOrgAmt>0</ReportableCompFromRltdOrgAmt>
        <OtherCompensationAmt>9547</OtherCompensationAmt>
      </Form990PartVIISectionAGrp>
      <Form990PartVIISectionAGrp>
        <PersonNm>PETER YANUL</PersonNm>
        <TitleTxt>CFO</TitleTxt>
        <AverageHoursPerWeekRt>40.00</AverageHoursPerWeekRt>
        <OfficerInd>X</OfficerInd>
        <ReportableCompFromOrgAmt>230000</ReportableCompFromOrgAmt>
        <ReportableCompFromRltdOrgAmt>0</ReportableCompFromRltdOrgAmt>
        <OtherCompensationAmt>8012</OtherCompensationAmt>
      </Form990PartVIISectionAGrp>
      <Form990PartVIISectionAGrp>
        <PersonNm>ANGELA CASE</PersonNm>
        <TitleTxt>FORMER CONTR</TitleTxt>
        <AverageHoursPerWeekRt>40.00</AverageHoursPerWeekRt>
        <OfficerInd>X</OfficerInd>
        <ReportableCompFromOrgAmt>0</ReportableCompFromOrgAmt>
        <ReportableCompFromRltdOrgAmt>0</ReportableCompFromRltdOrgAmt>
        <OtherCompensationAmt>0</OtherCompensationAmt>
      </Form990PartVIISectionAGrp>
      <Form990PartVIISectionAGrp>
        <PersonNm>MICHAEL SPEIGLE</PersonNm>
        <TitleTxt>CONTROLLER</TitleTxt>
        <AverageHoursPerWeekRt>40.00</AverageHoursPerWeekRt>
        <OfficerInd>X</OfficerInd>
        <ReportableCompFromOrgAmt>0</ReportableCompFromOrgAmt>
        <ReportableCompFromRltdOrgAmt>0</ReportableCompFromRltdOrgAmt>
        <OtherCompensationAmt>0</OtherCompensationAmt>
      </Form990PartVIISectionAGrp>
      <Form990PartVIISectionAGrp>
        <PersonNm>SHAWN LEVY</PersonNm>
        <TitleTxt>PRINCIPAL IN</TitleTxt>
        <AverageHoursPerWeekRt>40.00</AverageHoursPerWeekRt>
        <KeyEmployeeInd>X</KeyEmployeeInd>
        <ReportableCompFromOrgAmt>400000</ReportableCompFromOrgAmt>
        <ReportableCompFromRltdOrgAmt>0</ReportableCompFromRltdOrgAmt>
        <OtherCompensationAmt>32600</OtherCompensationAmt>
      </Form990PartVIISectionAGrp>
      <Form990PartVIISectionAGrp>
        <PersonNm>DAVID P BICK</PersonNm>
        <TitleTxt>PRINCIPAL IN</TitleTxt>
        <AverageHoursPerWeekRt>40.00</AverageHoursPerWeekRt>
        <KeyEmployeeInd>X</KeyEmployeeInd>
        <ReportableCompFromOrgAmt>354760</ReportableCompFromOrgAmt>
        <ReportableCompFromRltdOrgAmt>0</ReportableCompFromRltdOrgAmt>
        <OtherCompensationAmt>32600</OtherCompensationAmt>
      </Form990PartVIISectionAGrp>
      <Form990PartVIISectionAGrp>
        <PersonNm>GREGORY BARSH</PersonNm>
        <TitleTxt>PRINCIPAL IN</TitleTxt>
        <AverageHoursPerWeekRt>40.00</AverageHoursPerWeekRt>
        <KeyEmployeeInd>X</KeyEmployeeInd>
        <ReportableCompFromOrgAmt>342898</ReportableCompFromOrgAmt>
        <ReportableCompFromRltdOrgAmt>0</ReportableCompFromRltdOrgAmt>
        <OtherCompensationAmt>32600</OtherCompensationAmt>
      </Form990PartVIISectionAGrp>
      <Form990PartVIISectionAGrp>
        <PersonNm>JEREMY SCHMUTZ</PersonNm>
        <TitleTxt>PRINCIPAL IN</TitleTxt>
        <AverageHoursPerWeekRt>40.00</AverageHoursPerWeekRt>
        <KeyEmployeeInd>X</KeyEmployeeInd>
        <ReportableCompFromOrgAmt>295133</ReportableCompFromOrgAmt>
        <ReportableCompFromRltdOrgAmt>0</ReportableCompFromRltdOrgAmt>
        <OtherCompensationAmt>27091</OtherCompensationAmt>
      </Form990PartVIISectionAGrp>
      <Form990PartVIISectionAGrp>
        <PersonNm>JANE GRIMWOOD</PersonNm>
        <TitleTxt>PRIN INVESTG</TitleTxt>
        <AverageHoursPerWeekRt>40.00</AverageHoursPerWeekRt>
        <KeyEmployeeInd>X</KeyEmployeeInd>
        <ReportableCompFromOrgAmt>265974</ReportableCompFromOrgAmt>
        <ReportableCompFromRltdOrgAmt>0</ReportableCompFromRltdOrgAmt>
        <OtherCompensationAmt>24213</OtherCompensationAmt>
      </Form990PartVIISectionAGrp>
      <Form990PartVIISectionAGrp>
        <PersonNm>NEIL LAMB</PersonNm>
        <TitleTxt>VP OF ED. OU</TitleTxt>
        <AverageHoursPerWeekRt>40.00</AverageHoursPerWeekRt>
        <KeyEmployeeInd>X</KeyEmployeeInd>
        <ReportableCompFromOrgAmt>260002</ReportableCompFromOrgAmt>
        <ReportableCompFromRltdOrgAmt>0</ReportableCompFromRltdOrgAmt>
        <OtherCompensationAmt>23830</OtherCompensationAmt>
      </Form990PartVIISectionAGrp>
      <Form990PartVIISectionAGrp>
        <PersonNm>ELIZABETH WORTHEY</PersonNm>
        <TitleTxt>PRINCIPAL IN</TitleTxt>
        <AverageHoursPerWeekRt>40.00</AverageHoursPerWeekRt>
        <KeyEmployeeInd>X</KeyEmployeeInd>
        <ReportableCompFromOrgAmt>249800</ReportableCompFromOrgAmt>
        <ReportableCompFromRltdOrgAmt>0</ReportableCompFromRltdOrgAmt>
        <OtherCompensationAmt>23779</OtherCompensationAmt>
      </Form990PartVIISectionAGrp>
      <Form990PartVIISectionAGrp>
        <PersonNm>DEVIN ABSHER</PersonNm>
        <TitleTxt>PRINCIPAL IN</TitleTxt>
        <AverageHoursPerWeekRt>40.00</AverageHoursPerWeekRt>
        <KeyEmployeeInd>X</KeyEmployeeInd>
        <ReportableCompFromOrgAmt>225018</ReportableCompFromOrgAmt>
        <ReportableCompFromRltdOrgAmt>0</ReportableCompFromRltdOrgAmt>
        <OtherCompensationAmt>18993</OtherCompensationAmt>
      </Form990PartVIISectionAGrp>
      <Form990PartVIISectionAGrp>
        <PersonNm>GREGORY COOPER</PersonNm>
        <TitleTxt>PRINCIPAL IN</TitleTxt>
        <AverageHoursPerWeekRt>40.00</AverageHoursPerWeekRt>
        <KeyEmployeeInd>X</KeyEmployeeInd>
        <ReportableCompFromOrgAmt>200010</ReportableCompFromOrgAmt>
        <ReportableCompFromRltdOrgAmt>0</ReportableCompFromRltdOrgAmt>
        <OtherCompensationAmt>16806</OtherCompensationAmt>
      </Form990PartVIISectionAGrp>
      <Form990PartVIISectionAGrp>
        <PersonNm>JIAN HAN</PersonNm>
        <TitleTxt>PRINCIPAL IN</TitleTxt>
        <AverageHoursPerWeekRt>40.00</AverageHoursPerWeekRt>
        <KeyEmployeeInd>X</KeyEmployeeInd>
        <ReportableCompFromOrgAmt>184021</ReportableCompFromOrgAmt>
        <ReportableCompFromRltdOrgAmt>0</ReportableCompFromRltdOrgAmt>
        <OtherCompensationAmt>17115</OtherCompensationAmt>
      </Form990PartVIISectionAGrp>
      <Form990PartVIISectionAGrp>
        <PersonNm>SARA COOPER</PersonNm>
        <TitleTxt>PRINCIPAL IN</TitleTxt>
        <AverageHoursPerWeekRt>40.00</AverageHoursPerWeekRt>
        <KeyEmployeeInd>X</KeyEmployeeInd>
        <ReportableCompFromOrgAmt>173936</ReportableCompFromOrgAmt>
        <ReportableCompFromRltdOrgAmt>0</ReportableCompFromRltdOrgAmt>
        <OtherCompensationAmt>15287</OtherCompensationAmt>
      </Form990PartVIISectionAGrp>
      <Form990PartVIISectionAGrp>
        <PersonNm>GREGG TYREE</PersonNm>
        <TitleTxt>DIR/OPER</TitleTxt>
        <AverageHoursPerWeekRt>40.00</AverageHoursPerWeekRt>
        <KeyEmployeeInd>X</KeyEmployeeInd>
        <ReportableCompFromOrgAmt>172135</ReportableCompFromOrgAmt>
        <ReportableCompFromRltdOrgAmt>0</ReportableCompFromRltdOrgAmt>
        <OtherCompensationAmt>6590</OtherCompensationAmt>
      </Form990PartVIISectionAGrp>
      <Form990PartVIISectionAGrp>
        <PersonNm>FLORENCIA BEHN</PersonNm>
        <TitleTxt>RESEARCH AFF</TitleTxt>
        <AverageHoursPerWeekRt>40.00</AverageHoursPerWeekRt>
        <KeyEmployeeInd>X</KeyEmployeeInd>
        <ReportableCompFromOrgAmt>165000</ReportableCompFromOrgAmt>
        <ReportableCompFromRltdOrgAmt>0</ReportableCompFromRltdOrgAmt>
        <OtherCompensationAmt>5900</OtherCompensationAmt>
      </Form990PartVIISectionAGrp>
      <Form990PartVIISectionAGrp>
        <PersonNm>KANKSHITA SWAMINATHAN</PersonNm>
        <TitleTxt>PRINCIPAL IN</TitleTxt>
        <AverageHoursPerWeekRt>40.00</AverageHoursPerWeekRt>
        <KeyEmployeeInd>X</KeyEmployeeInd>
        <ReportableCompFromOrgAmt>163470</ReportableCompFromOrgAmt>
        <ReportableCompFromRltdOrgAmt>0</ReportableCompFromRltdOrgAmt>
        <OtherCompensationAmt>14817</OtherCompensationAmt>
      </Form990PartVIISectionAGrp>
      <TotalReportableCompFromOrgAmt>4625382</TotalReportableCompFromOrgAmt>
      <TotalOtherCompensationAmt>342380</TotalOtherCompensationAmt>
      <IndivRcvdGreaterThan100KCnt>17</IndivRcvdGreaterThan100KCnt>
      <FormerOfcrEmployeesListedInd>false</FormerOfcrEmployeesListedInd>
      <TotalCompGreaterThan150KInd>true</TotalCompGreaterThan150KInd>
      <CompensationFromOtherSrcsInd>false</CompensationFromOtherSrcsInd>
      <ContractorCompensationGrp>
        <ContractorName>
          <BusinessName>
            <BusinessNameLine1Txt>BRASFIELD &amp; GORRIE LLC</BusinessNameLine1Txt>
          </BusinessName>
        </ContractorName>
        <ContractorAddress>
          <USAddress>
            <AddressLine1Txt>PO BOX 11407</AddressLine1Txt>
            <CityNm>BIRMINGHAM</CityNm>
            <StateAbbreviationCd>AL</StateAbbreviationCd>
            <ZIPCd>35246</ZIPCd>
          </USAddress>
        </ContractorAddress>
        <ServicesDesc>CONSTRUCTION</ServicesDesc>
        <CompensationAmt>7407012</CompensationAmt>
      </ContractorCompensationGrp>
      <ContractorCompensationGrp>
        <ContractorName>
          <BusinessName>
            <BusinessNameLine1Txt>LEASESOUTH LLC</BusinessNameLine1Txt>
          </BusinessName>
        </ContractorName>
        <ContractorAddress>
          <USAddress>
            <AddressLine1Txt>300 CLINTON AVENUE WEST</AddressLine1Txt>
            <AddressLine2Txt>SUITE 1</AddressLine2Txt>
            <CityNm>HUNTSVILLE</CityNm>
            <StateAbbreviationCd>AL</StateAbbreviationCd>
            <ZIPCd>35801</ZIPCd>
          </USAddress>
        </ContractorAddress>
        <ServicesDesc>LEASING</ServicesDesc>
        <CompensationAmt>459670</CompensationAmt>
      </ContractorCompensationGrp>
      <ContractorCompensationGrp>
        <ContractorName>
          <BusinessName>
            <BusinessNameLine1Txt>BRADLEY ARANT</BusinessNameLine1Txt>
          </BusinessName>
        </ContractorName>
        <ContractorAddress>
          <USAddress>
            <AddressLine1Txt>200 CLINTON AVENUE WEST</AddressLine1Txt>
            <CityNm>HUNTSVILLE</CityNm>
            <StateAbbreviationCd>AL</StateAbbreviationCd>
            <ZIPCd>35801</ZIPCd>
          </USAddress>
        </ContractorAddress>
        <ServicesDesc>LEGAL SERVICES</ServicesDesc>
        <CompensationAmt>395796</CompensationAmt>
      </ContractorCompensationGrp>
      <ContractorCompensationGrp>
        <ContractorName>
          <BusinessName>
            <BusinessNameLine1Txt>EGL GENETIC DIAGNOSTICS LLC</BusinessNameLine1Txt>
          </BusinessName>
        </ContractorName>
        <ContractorAddress>
          <USAddress>
            <AddressLine1Txt>2460 MOUNTAIN INDUSTRIAL BLVD</AddressLine1Txt>
            <CityNm>TUCKER</CityNm>
            <StateAbbreviationCd>GA</StateAbbreviationCd>
            <ZIPCd>30084</ZIPCd>
          </USAddress>
        </ContractorAddress>
        <ServicesDesc>SANGER SEQUENCI</ServicesDesc>
        <CompensationAmt>167710</CompensationAmt>
      </ContractorCompensationGrp>
      <ContractorCompensationGrp>
        <ContractorName>
          <BusinessName>
            <BusinessNameLine1Txt>JACKSON CENTER LLC</BusinessNameLine1Txt>
          </BusinessName>
        </ContractorName>
        <ContractorAddress>
          <USAddress>
            <AddressLine1Txt>600 GENOME WAY</AddressLine1Txt>
            <CityNm>HUNTSVILLE</CityNm>
            <StateAbbreviationCd>AL</StateAbbreviationCd>
            <ZIPCd>35806</ZIPCd>
          </USAddress>
        </ContractorAddress>
        <ServicesDesc>EVENT HOSTING</ServicesDesc>
        <CompensationAmt>137786</CompensationAmt>
      </ContractorCompensationGrp>
      <CntrctRcvdGreaterThan100KCnt>7</CntrctRcvdGreaterThan100KCnt>
      <RelatedOrganizationsAmt>8465732</RelatedOrganizationsAmt>
      <GovernmentGrantsAmt>18280264</GovernmentGrantsAmt>
      <AllOtherContributionsAmt>18678179</AllOtherContributionsAmt>
      <TotalContributionsAmt>45424175</TotalContributionsAmt>
      <ProgramServiceRevenueGrp>
        <Desc>SERVICE REVENUE</Desc>
        <TotalRevenueColumnAmt>26811067</TotalRevenueColumnAmt>
        <RelatedOrExemptFuncIncomeAmt>26811067</RelatedOrExemptFuncIncomeAmt>
      </ProgramServiceRevenueGrp>
      <ProgramServiceRevenueGrp>
        <Desc>FEDERAL CONTRACTS</Desc>
        <TotalRevenueColumnAmt>4938044</TotalRevenueColumnAmt>
        <RelatedOrExemptFuncIncomeAmt>4938044</RelatedOrExemptFuncIncomeAmt>
      </ProgramServiceRevenueGrp>
      <TotalProgramServiceRevenueAmt>31749111</TotalProgramServiceRevenueAmt>
      <InvestmentIncomeGrp>
        <TotalRevenueColumnAmt>62489</TotalRevenueColumnAmt>
        <ExclusionAmt>62489</ExclusionAmt>
      </InvestmentIncomeGrp>
      <RoyaltiesRevenueGrp>
        <TotalRevenueColumnAmt>45211</TotalRevenueColumnAmt>
        <ExclusionAmt>45211</ExclusionAmt>
      </RoyaltiesRevenueGrp>
      <GrossRentsGrp>
        <RealAmt>2282934</RealAmt>
      </GrossRentsGrp>
      <RentalIncomeOrLossGrp>
        <RealAmt>2282934</RealAmt>
      </RentalIncomeOrLossGrp>
      <NetRentalIncomeOrLossGrp>
        <TotalRevenueColumnAmt>2282934</TotalRevenueColumnAmt>
        <ExclusionAmt>2282934</ExclusionAmt>
      </NetRentalIncomeOrLossGrp>
      <GrossAmountSalesAssetsGrp>
        <SecuritiesAmt>1855898</SecuritiesAmt>
        <OtherAmt>2160000</OtherAmt>
      </GrossAmountSalesAssetsGrp>
      <LessCostOthBasisSalesExpnssGrp>
        <SecuritiesAmt>1812130</SecuritiesAmt>
        <OtherAmt>1099132</OtherAmt>
      </LessCostOthBasisSalesExpnssGrp>
      <GainOrLossGrp>
        <SecuritiesAmt>43768</SecuritiesAmt>
        <OtherAmt>1060868</OtherAmt>
      </GainOrLossGrp>
      <NetGainOrLossInvestmentsGrp>
        <TotalRevenueColumnAmt>1104636</TotalRevenueColumnAmt>
        <RelatedOrExemptFuncIncomeAmt>1104636</RelatedOrExemptFuncIncomeAmt>
      </NetGainOrLossInvestmentsGrp>
      <TotalRevenueGrp>
        <TotalRevenueColumnAmt>80668556</TotalRevenueColumnAmt>
        <RelatedOrExemptFuncIncomeAmt>32853747</RelatedOrExemptFuncIncomeAmt>
        <ExclusionAmt>2390634</ExclusionAmt>
      </TotalRevenueGrp>
      <CompCurrentOfcrDirectorsGrp>
        <TotalAmt>2223117</TotalAmt>
        <ProgramServicesAmt>1023586</ProgramServicesAmt>
        <ManagementAndGeneralAmt>1199531</ManagementAndGeneralAmt>
      </CompCurrentOfcrDirectorsGrp>
      <OtherSalariesAndWagesGrp>
        <TotalAmt>5160544</TotalAmt>
        <ProgramServicesAmt>1491475</ProgramServicesAmt>
        <ManagementAndGeneralAmt>3479923</ManagementAndGeneralAmt>
        <FundraisingAmt>189146</FundraisingAmt>
      </OtherSalariesAndWagesGrp>
      <PensionPlanContributionsGrp>
        <TotalAmt>840861</TotalAmt>
        <ProgramServicesAmt>608810</ProgramServicesAmt>
        <ManagementAndGeneralAmt>223368</ManagementAndGeneralAmt>
        <FundraisingAmt>8683</FundraisingAmt>
      </PensionPlanContributionsGrp>
      <OtherEmployeeBenefitsGrp>
        <TotalAmt>2601213</TotalAmt>
        <ProgramServicesAmt>1573840</ProgramServicesAmt>
        <ManagementAndGeneralAmt>975182</ManagementAndGeneralAmt>
        <FundraisingAmt>52191</FundraisingAmt>
      </OtherEmployeeBenefitsGrp>
      <PayrollTaxesGrp>
        <TotalAmt>1077646</TotalAmt>
        <ProgramServicesAmt>769119</ProgramServicesAmt>
        <ManagementAndGeneralAmt>292599</ManagementAndGeneralAmt>
        <FundraisingAmt>15928</FundraisingAmt>
      </PayrollTaxesGrp>
      <FeesForServicesLegalGrp>
        <TotalAmt>234650</TotalAmt>
        <ManagementAndGeneralAmt>234650</ManagementAndGeneralAmt>
      </FeesForServicesLegalGrp>
      <FeesForServicesAccountingGrp>
        <TotalAmt>124446</TotalAmt>
        <ManagementAndGeneralAmt>124446</ManagementAndGeneralAmt>
      </FeesForServicesAccountingGrp>
      <FeesForServicesLobbyingGrp>
        <TotalAmt>206000</TotalAmt>
        <ManagementAndGeneralAmt>206000</ManagementAndGeneralAmt>
      </FeesForServicesLobbyingGrp>
      <FeesForServicesProfFundraising>
        <TotalAmt>116375</TotalAmt>
        <FundraisingAmt>116375</FundraisingAmt>
      </FeesForServicesProfFundraising>
      <FeesForSrvcInvstMgmntFeesGrp>
        <TotalAmt>14426</TotalAmt>
        <ManagementAndGeneralAmt>14426</ManagementAndGeneralAmt>
      </FeesForSrvcInvstMgmntFeesGrp>
      <FeesForServicesOtherGrp>
        <TotalAmt>154806</TotalAmt>
        <ProgramServicesAmt>246</ProgramServicesAmt>
        <ManagementAndGeneralAmt>28931</ManagementAndGeneralAmt>
        <FundraisingAmt>125629</FundraisingAmt>
      </FeesForServicesOtherGrp>
      <AdvertisingGrp>
        <TotalAmt>38529</TotalAmt>
        <ProgramServicesAmt>1122</ProgramServicesAmt>
        <ManagementAndGeneralAmt>37407</ManagementAndGeneralAmt>
      </AdvertisingGrp>
      <OfficeExpensesGrp>
        <TotalAmt>2358621</TotalAmt>
        <ProgramServicesAmt>1122350</ProgramServicesAmt>
        <ManagementAndGeneralAmt>1200544</ManagementAndGeneralAmt>
        <FundraisingAmt>35727</FundraisingAmt>
      </OfficeExpensesGrp>
      <InformationTechnologyGrp>
        <TotalAmt>2738936</TotalAmt>
        <ManagementAndGeneralAmt>2738936</ManagementAndGeneralAmt>
      </InformationTechnologyGrp>
      <OccupancyGrp>
        <TotalAmt>8406172</TotalAmt>
        <ProgramServicesAmt>1672828</ProgramServicesAmt>
        <ManagementAndGeneralAmt>6726619</ManagementAndGeneralAmt>
        <FundraisingAmt>6725</FundraisingAmt>
      </OccupancyGrp>
      <TravelGrp>
        <TotalAmt>238501</TotalAmt>
        <ProgramServicesAmt>73321</ProgramServicesAmt>
        <ManagementAndGeneralAmt>156330</ManagementAndGeneralAmt>
        <FundraisingAmt>8850</FundraisingAmt>
      </TravelGrp>
      <InterestGrp>
        <TotalAmt>190987</TotalAmt>
        <ManagementAndGeneralAmt>190987</ManagementAndGeneralAmt>
      </InterestGrp>
      <DepreciationDepletionGrp>
        <TotalAmt>1485322</TotalAmt>
        <ProgramServicesAmt>560998</ProgramServicesAmt>
        <ManagementAndGeneralAmt>918897</ManagementAndGeneralAmt>
        <FundraisingAmt>5427</FundraisingAmt>
      </DepreciationDepletionGrp>
      <InsuranceGrp>
        <TotalAmt>180636</TotalAmt>
        <ManagementAndGeneralAmt>180636</ManagementAndGeneralAmt>
      </InsuranceGrp>
      <OtherExpensesGrp>
        <Desc>DIRECT EXPENDITURES</Desc>
        <TotalAmt>41355351</TotalAmt>
        <ProgramServicesAmt>41355351</ProgramServicesAmt>
      </OtherExpensesGrp>
      <OtherExpensesGrp>
        <Desc>CONSULTING FEES</Desc>
        <TotalAmt>611840</TotalAmt>
        <ProgramServicesAmt>438456</ProgramServicesAmt>
        <ManagementAndGeneralAmt>173384</ManagementAndGeneralAmt>
      </OtherExpensesGrp>
      <OtherExpensesGrp>
        <Desc>OUTSIDE SERVICES</Desc>
        <TotalAmt>519599</TotalAmt>
        <ProgramServicesAmt>238</ProgramServicesAmt>
        <ManagementAndGeneralAmt>481982</ManagementAndGeneralAmt>
        <FundraisingAmt>37379</FundraisingAmt>
      </OtherExpensesGrp>
      <OtherExpensesGrp>
        <Desc>CONTRACT LABOR</Desc>
        <TotalAmt>258316</TotalAmt>
        <ManagementAndGeneralAmt>258316</ManagementAndGeneralAmt>
      </OtherExpensesGrp>
      <AllOtherExpensesGrp>
        <TotalAmt>595231</TotalAmt>
        <ProgramServicesAmt>396477</ProgramServicesAmt>
        <ManagementAndGeneralAmt>181563</ManagementAndGeneralAmt>
        <FundraisingAmt>17191</FundraisingAmt>
      </AllOtherExpensesGrp>
      <TotalFunctionalExpensesGrp>
        <TotalAmt>71732125</TotalAmt>
        <ProgramServicesAmt>51088217</ProgramServicesAmt>
        <ManagementAndGeneralAmt>20024657</ManagementAndGeneralAmt>
        <FundraisingAmt>619251</FundraisingAmt>
      </TotalFunctionalExpensesGrp>
      <CashNonInterestBearingGrp>
        <BOYAmt>2901288</BOYAmt>
        <EOYAmt>5391092</EOYAmt>
      </CashNonInterestBearingGrp>
      <PledgesAndGrantsReceivableGrp>
        <BOYAmt>8384134</BOYAmt>
        <EOYAmt>2924401</EOYAmt>
      </PledgesAndGrantsReceivableGrp>
      <AccountsReceivableGrp>
        <BOYAmt>4187938</BOYAmt>
        <EOYAmt>3934158</EOYAmt>
      </AccountsReceivableGrp>
      <PrepaidExpensesDefrdChargesGrp>
        <BOYAmt>2251589</BOYAmt>
        <EOYAmt>3633494</EOYAmt>
      </PrepaidExpensesDefrdChargesGrp>
      <LandBldgEquipCostOrOtherBssAmt>141028600</LandBldgEquipCostOrOtherBssAmt>
      <LandBldgEquipAccumDeprecAmt>39469739</LandBldgEquipAccumDeprecAmt>
      <LandBldgEquipBasisNetGrp>
        <BOYAmt>74887000</BOYAmt>
        <EOYAmt>101558861</EOYAmt>
      </LandBldgEquipBasisNetGrp>
      <InvestmentsPubTradedSecGrp>
        <BOYAmt>2076094</BOYAmt>
        <EOYAmt>2012563</EOYAmt>
      </InvestmentsPubTradedSecGrp>
      <InvestmentsOtherSecuritiesGrp>
        <BOYAmt>1012000</BOYAmt>
        <EOYAmt>1012000</EOYAmt>
      </InvestmentsOtherSecuritiesGrp>
      <IntangibleAssetsGrp>
        <BOYAmt>502483</BOYAmt>
        <EOYAmt>537020</EOYAmt>
      </IntangibleAssetsGrp>
      <OtherAssetsTotalGrp>
        <BOYAmt>21183462</BOYAmt>
        <EOYAmt>2520526</EOYAmt>
      </OtherAssetsTotalGrp>
      <TotalAssetsGrp>
        <BOYAmt>117385988</BOYAmt>
        <EOYAmt>123524115</EOYAmt>
      </TotalAssetsGrp>
      <AccountsPayableAccrExpnssGrp>
        <BOYAmt>8621133</BOYAmt>
        <EOYAmt>5645903</EOYAmt>
      </AccountsPayableAccrExpnssGrp>
      <OtherLiabilitiesGrp>
        <BOYAmt>14027959</BOYAmt>
        <EOYAmt>14364238</EOYAmt>
      </OtherLiabilitiesGrp>
      <TotalLiabilitiesGrp>
        <BOYAmt>22649092</BOYAmt>
        <EOYAmt>20010141</EOYAmt>
      </TotalLiabilitiesGrp>
      <OrganizationFollowsSFAS117Ind>X</OrganizationFollowsSFAS117Ind>
      <UnrestrictedNetAssetsGrp>
        <BOYAmt>88354725</BOYAmt>
        <EOYAmt>99889624</EOYAmt>
      </UnrestrictedNetAssetsGrp>
      <TemporarilyRstrNetAssetsGrp>
        <BOYAmt>6382171</BOYAmt>
        <EOYAmt>3624350</EOYAmt>
      </TemporarilyRstrNetAssetsGrp>
      <TotalNetAssetsFundBalanceGrp>
        <BOYAmt>94736896</BOYAmt>
        <EOYAmt>103513974</EOYAmt>
      </TotalNetAssetsFundBalanceGrp>
      <TotLiabNetAssetsFundBalanceGrp>
        <BOYAmt>117385988</BOYAmt>
        <EOYAmt>123524115</EOYAmt>
      </TotLiabNetAssetsFundBalanceGrp>
      <ReconcilationRevenueExpnssAmt>8936431</ReconcilationRevenueExpnssAmt>
      <NetUnrlzdGainsLossesInvstAmt>-159353</NetUnrlzdGainsLossesInvstAmt>
      <MethodOfAccountingAccrualInd>X</MethodOfAccountingAccrualInd>
      <AccountantCompileOrReviewInd>false</AccountantCompileOrReviewInd>
      <FSAuditedInd>true</FSAuditedInd>
      <FSAuditedBasisGrp>
        <ConsolidatedBasisFinclStmtInd>X</ConsolidatedBasisFinclStmtInd>
      </FSAuditedBasisGrp>
      <AuditCommitteeInd>true</AuditCommitteeInd>
      <FederalGrantAuditRequiredInd>true</FederalGrantAuditRequiredInd>
      <FederalGrantAuditPerformedInd>true</FederalGrantAuditPerformedInd>
    </IRS990>
    <IRS990ScheduleA documentId="RetDoc9">
      <PublicOrganization170Ind>X</PublicOrganization170Ind>
      <GiftsGrantsContriRcvd170Grp>
        <CurrentTaxYearMinus4YearsAmt>14113973</CurrentTaxYearMinus4YearsAmt>
        <CurrentTaxYearMinus3YearsAmt>17587426</CurrentTaxYearMinus3YearsAmt>
        <CurrentTaxYearMinus2YearsAmt>43947417</CurrentTaxYearMinus2YearsAmt>
        <CurrentTaxYearMinus1YearAmt>23581451</CurrentTaxYearMinus1YearAmt>
        <CurrentTaxYearAmt>45424175</CurrentTaxYearAmt>
        <TotalAmt>144654442</TotalAmt>
      </GiftsGrantsContriRcvd170Grp>
      <TotalCalendarYear170Grp>
        <CurrentTaxYearMinus4YearsAmt>14113973</CurrentTaxYearMinus4YearsAmt>
        <CurrentTaxYearMinus3YearsAmt>17587426</CurrentTaxYearMinus3YearsAmt>
        <CurrentTaxYearMinus2YearsAmt>43947417</CurrentTaxYearMinus2YearsAmt>
        <CurrentTaxYearMinus1YearAmt>23581451</CurrentTaxYearMinus1YearAmt>
        <CurrentTaxYearAmt>45424175</CurrentTaxYearAmt>
        <TotalAmt>144654442</TotalAmt>
      </TotalCalendarYear170Grp>
      <SubstantialContributorsTotAmt>11933560</SubstantialContributorsTotAmt>
      <PublicSupportTotal170Amt>132720882</PublicSupportTotal170Amt>
      <GrossInvestmentIncome170Grp>
        <CurrentTaxYearMinus4YearsAmt>3163362</CurrentTaxYearMinus4YearsAmt>
        <CurrentTaxYearMinus3YearsAmt>3089498</CurrentTaxYearMinus3YearsAmt>
        <CurrentTaxYearMinus2YearsAmt>2051544</CurrentTaxYearMinus2YearsAmt>
        <CurrentTaxYearMinus1YearAmt>2615117</CurrentTaxYearMinus1YearAmt>
        <CurrentTaxYearAmt>2390634</CurrentTaxYearAmt>
        <TotalAmt>13310155</TotalAmt>
      </GrossInvestmentIncome170Grp>
      <TotalSupportAmt>157964597</TotalSupportAmt>
      <GrossReceiptsRltdActivitiesAmt>56798951</GrossReceiptsRltdActivitiesAmt>
      <PublicSupportCY170Pct>0.84020</PublicSupportCY170Pct>
      <PublicSupportPY170Pct>0.89080</PublicSupportPY170Pct>
      <ThirtyThrPctSuprtTestsCY170Ind>X</ThirtyThrPctSuprtTestsCY170Ind>
    </IRS990ScheduleA>
    <IRS990ScheduleB documentId="RetDoc1">
      <ContributorInformationGrp>
        <ContributorNum>RESTRICTED</ContributorNum>
        <ContributorBusinessName>
          <BusinessNameLine1>RESTRICTED</BusinessNameLine1>
        </ContributorBusinessName>
        <ContributorUSAddress>
          <AddressLine1>RESTRICTED</AddressLine1>
          <AddressLine2>RESTRICTED</AddressLine2>
          <City>RESTRICTED</City>
          <State>RESTRICTED</State>
          <ZIPCode>RESTRICTED</ZIPCode>
        </ContributorUSAddress>
        <TotalContributionsAmt>RESTRICTED</TotalContributionsAmt>
      </ContributorInformationGrp>
    </IRS990ScheduleB>
    <IRS990ScheduleC documentId="RetDoc3">
      <VolunteersInd>false</VolunteersInd>
      <PaidStaffOrManagementInd>false</PaidStaffOrManagementInd>
      <MediaAdvertisementsInd>false</MediaAdvertisementsInd>
      <MailingsMembersInd>false</MailingsMembersInd>
      <PublicationsOrBroadcastInd>false</PublicationsOrBroadcastInd>
      <GrantsOtherOrganizationsInd>false</GrantsOtherOrganizationsInd>
      <DirectContactLegislatorsInd>true</DirectContactLegislatorsInd>
      <DirectContactLegislatorsAmt>206000</DirectContactLegislatorsAmt>
      <RalliesDemonstrationsInd>false</RalliesDemonstrationsInd>
      <OtherActivitiesInd>false</OtherActivitiesInd>
      <TotalLobbyingExpendituresAmt>206000</TotalLobbyingExpendituresAmt>
      <NotDescribedSection501c3Ind>false</NotDescribedSection501c3Ind>
      <SupplementalInformationDetail>
        <FormAndLineReferenceDesc>SCHEDULE C, PART II-B, LINE 1</FormAndLineReferenceDesc>
        <ExplanationTxt>PAYMENTS TO LOBBYING ORGANIZATIONS FOR STATE AND LOCAL REPRESENTATION</ExplanationTxt>
      </SupplementalInformationDetail>
    </IRS990ScheduleC>
    <IRS990ScheduleD documentId="RetDoc4">
      <CYMinus2YrEndwmtFundGrp>
        <BeginningYearBalanceAmt>54112</BeginningYearBalanceAmt>
        <OtherExpendituresAmt>54112</OtherExpendituresAmt>
      </CYMinus2YrEndwmtFundGrp>
      <CYMinus3YrEndwmtFundGrp>
        <BeginningYearBalanceAmt>32785580</BeginningYearBalanceAmt>
        <InvestmentEarningsOrLossesAmt>881631</InvestmentEarningsOrLossesAmt>
        <OtherExpendituresAmt>33362376</OtherExpendituresAmt>
        <AdministrativeExpensesAmt>250723</AdministrativeExpensesAmt>
        <EndYearBalanceAmt>54112</EndYearBalanceAmt>
      </CYMinus3YrEndwmtFundGrp>
      <CYMinus4YrEndwmtFundGrp>
        <BeginningYearBalanceAmt>33451698</BeginningYearBalanceAmt>
        <InvestmentEarningsOrLossesAmt>1243246</InvestmentEarningsOrLossesAmt>
        <OtherExpendituresAmt>1640865</OtherExpendituresAmt>
        <AdministrativeExpensesAmt>268499</AdministrativeExpensesAmt>
        <EndYearBalanceAmt>32785580</EndYearBalanceAmt>
      </CYMinus4YrEndwmtFundGrp>
      <BoardDesignatedBalanceEOYPct>1.00000</BoardDesignatedBalanceEOYPct>
      <EndowmentsHeldUnrelatedOrgInd>false</EndowmentsHeldUnrelatedOrgInd>
      <EndowmentsHeldRelatedOrgInd>false</EndowmentsHeldRelatedOrgInd>
      <LandGrp>
        <OtherCostOrOtherBasisAmt>9004798</OtherCostOrOtherBasisAmt>
        <BookValueAmt>9004798</BookValueAmt>
      </LandGrp>
      <BuildingsGrp>
        <OtherCostOrOtherBasisAmt>103683554</OtherCostOrOtherBasisAmt>
        <DepreciationAmt>18609191</DepreciationAmt>
        <BookValueAmt>85074363</BookValueAmt>
      </BuildingsGrp>
      <EquipmentGrp>
        <OtherCostOrOtherBasisAmt>28340248</OtherCostOrOtherBasisAmt>
        <DepreciationAmt>20860548</DepreciationAmt>
        <BookValueAmt>7479700</BookValueAmt>
      </EquipmentGrp>
      <TotalBookValueLandBuildingsAmt>101558861</TotalBookValueLandBuildingsAmt>
      <OtherLiabilitiesOrgGrp>
        <Desc>LINE OF CREDIT FIRST COMMERCIAL</Desc>
        <Amt>6717336</Amt>
      </OtherLiabilitiesOrgGrp>
      <OtherLiabilitiesOrgGrp>
        <Desc>DEFERRED INCOME</Desc>
        <Amt>4593183</Amt>
      </OtherLiabilitiesOrgGrp>
      <OtherLiabilitiesOrgGrp>
        <Desc>ACCRUED EXPENSES</Desc>
        <Amt>1729835</Amt>
      </OtherLiabilitiesOrgGrp>
      <OtherLiabilitiesOrgGrp>
        <Desc>CAPITAL LEASE</Desc>
        <Amt>629860</Amt>
      </OtherLiabilitiesOrgGrp>
      <OtherLiabilitiesOrgGrp>
        <Desc>INTERCOMPANY HSC</Desc>
        <Amt>492645</Amt>
      </OtherLiabilitiesOrgGrp>
      <OtherLiabilitiesOrgGrp>
        <Desc>REFUNDABLE ADVANCE</Desc>
        <Amt>201379</Amt>
      </OtherLiabilitiesOrgGrp>
      <TotalLiabilityAmt>14364238</TotalLiabilityAmt>
    </IRS990ScheduleD>
    <IRS990ScheduleG documentId="RetDoc5">
      <MailSolicitationsInd>X</MailSolicitationsInd>
      <EmailSolicitationsInd>X</EmailSolicitationsInd>
      <PhoneSolicitationsInd>X</PhoneSolicitationsInd>
      <InPersonSolicitationsInd>X</InPersonSolicitationsInd>
      <SolicitationOfNonGovtGrantsInd>X</SolicitationOfNonGovtGrantsInd>
      <SolicitationOfGovtGrantsInd>X</SolicitationOfGovtGrantsInd>
      <SpecialFundraisingEventsInd>X</SpecialFundraisingEventsInd>
      <AgrmtProfFundraisingActyInd>true</AgrmtProfFundraisingActyInd>
      <FundraiserActivityInfoGrp>
        <PersonNm>THE MESSINA GROUP</PersonNm>
        <USAddress>
          <AddressLine1Txt>1155 CONNECTICUT AVE NW</AddressLine1Txt>
          <CityNm>WASHINGTON</CityNm>
          <StateAbbreviationCd>DC</StateAbbreviationCd>
          <ZIPCd>20036</ZIPCd>
        </USAddress>
        <ActivityTxt>ADVANCEMEN</ActivityTxt>
        <FundraiserControlOfFundsInd>false</FundraiserControlOfFundsInd>
        <RetainedByContractorAmt>50000</RetainedByContractorAmt>
        <NetToOrganizationAmt>-50000</NetToOrganizationAmt>
      </FundraiserActivityInfoGrp>
      <FundraiserActivityInfoGrp>
        <PersonNm>LIZ MURRAY</PersonNm>
        <USAddress>
          <AddressLine1Txt>1214 A INGLESIDE AVENUE</AddressLine1Txt>
          <CityNm>MCLEAN</CityNm>
          <StateAbbreviationCd>VA</StateAbbreviationCd>
          <ZIPCd>22101</ZIPCd>
        </USAddress>
        <ActivityTxt>ADVANCEMEN</ActivityTxt>
        <FundraiserControlOfFundsInd>false</FundraiserControlOfFundsInd>
        <RetainedByContractorAmt>45000</RetainedByContractorAmt>
        <NetToOrganizationAmt>-45000</NetToOrganizationAmt>
      </FundraiserActivityInfoGrp>
      <FundraiserActivityInfoGrp>
        <PersonNm>SUZANNE MATTHEWS</PersonNm>
        <USAddress>
          <AddressLine1Txt>753 PETTUS ROAD</AddressLine1Txt>
          <CityNm>MADISON</CityNm>
          <StateAbbreviationCd>AL</StateAbbreviationCd>
          <ZIPCd>35757</ZIPCd>
        </USAddress>
        <ActivityTxt>ADVANCEMEN</ActivityTxt>
        <FundraiserControlOfFundsInd>false</FundraiserControlOfFundsInd>
        <RetainedByContractorAmt>11375</RetainedByContractorAmt>
        <NetToOrganizationAmt>-11375</NetToOrganizationAmt>
      </FundraiserActivityInfoGrp>
      <FundraiserActivityInfoGrp>
        <PersonNm>LOWERY DEVELOPMENT</PersonNm>
        <USAddress>
          <AddressLine1Txt>145 WEST 58TH STREET 12H</AddressLine1Txt>
          <CityNm>NEW YORK</CityNm>
          <StateAbbreviationCd>NY</StateAbbreviationCd>
          <ZIPCd>10019</ZIPCd>
        </USAddress>
        <ActivityTxt>ADVANCEMEN</ActivityTxt>
        <FundraiserControlOfFundsInd>false</FundraiserControlOfFundsInd>
        <RetainedByContractorAmt>10000</RetainedByContractorAmt>
        <NetToOrganizationAmt>-10000</NetToOrganizationAmt>
      </FundraiserActivityInfoGrp>
      <TotalRetainedByContractorsAmt>116375</TotalRetainedByContractorsAmt>
      <TotalNetToOrganizationAmt>-116375</TotalNetToOrganizationAmt>
      <AllStatesCd>All States</AllStatesCd>
    </IRS990ScheduleG>
    <IRS990ScheduleJ documentId="RetDoc6">
      <FirstClassOrCharterTravelInd>X</FirstClassOrCharterTravelInd>
      <WrittenPolicyRefTAndEExpnssInd>true</WrittenPolicyRefTAndEExpnssInd>
      <SubstantiationRequiredInd>false</SubstantiationRequiredInd>
      <BoardOrCommitteeApprovalInd>X</BoardOrCommitteeApprovalInd>
      <SeverancePaymentInd>false</SeverancePaymentInd>
      <SupplementalNonqualRtrPlanInd>false</SupplementalNonqualRtrPlanInd>
      <EquityBasedCompArrngmInd>false</EquityBasedCompArrngmInd>
      <CompBasedOnRevenueOfFlngOrgInd>false</CompBasedOnRevenueOfFlngOrgInd>
      <CompBsdOnRevRelatedOrgsInd>false</CompBsdOnRevRelatedOrgsInd>
      <CompBsdNetEarnsFlngOrgInd>false</CompBsdNetEarnsFlngOrgInd>
      <CompBsdNetEarnsRltdOrgsInd>false</CompBsdNetEarnsRltdOrgsInd>
      <AnyNonFixedPaymentsInd>false</AnyNonFixedPaymentsInd>
      <InitialContractExceptionInd>false</InitialContractExceptionInd>
      <RltdOrgOfficerTrstKeyEmplGrp>
        <PersonNm>RICHARD MYERS</PersonNm>
        <TitleTxt>PRESIDENT</TitleTxt>
        <BaseCompensationFilingOrgAmt>693225</BaseCompensationFilingOrgAmt>
        <NontaxableBenefitsFilingOrgAmt>32600</NontaxableBenefitsFilingOrgAmt>
        <TotalCompensationFilingOrgAmt>725825</TotalCompensationFilingOrgAmt>
      </RltdOrgOfficerTrstKeyEmplGrp>
      <RltdOrgOfficerTrstKeyEmplGrp>
        <PersonNm>CARTER WELLS</PersonNm>
        <TitleTxt>VP ECON DEVELOPMENT</TitleTxt>
        <BaseCompensationFilingOrgAmt>250000</BaseCompensationFilingOrgAmt>
        <NontaxableBenefitsFilingOrgAmt>9547</NontaxableBenefitsFilingOrgAmt>
        <TotalCompensationFilingOrgAmt>259547</TotalCompensationFilingOrgAmt>
      </RltdOrgOfficerTrstKeyEmplGrp>
      <RltdOrgOfficerTrstKeyEmplGrp>
        <PersonNm>PETER YANUL</PersonNm>
        <TitleTxt>CFO</TitleTxt>
        <BaseCompensationFilingOrgAmt>230000</BaseCompensationFilingOrgAmt>
        <NontaxableBenefitsFilingOrgAmt>8012</NontaxableBenefitsFilingOrgAmt>
        <TotalCompensationFilingOrgAmt>238012</TotalCompensationFilingOrgAmt>
      </RltdOrgOfficerTrstKeyEmplGrp>
      <RltdOrgOfficerTrstKeyEmplGrp>
        <PersonNm>SHAWN LEVY</PersonNm>
        <TitleTxt>PRINCIPAL INVESTG</TitleTxt>
        <BaseCompensationFilingOrgAmt>400000</BaseCompensationFilingOrgAmt>
        <NontaxableBenefitsFilingOrgAmt>32600</NontaxableBenefitsFilingOrgAmt>
        <TotalCompensationFilingOrgAmt>432600</TotalCompensationFilingOrgAmt>
      </RltdOrgOfficerTrstKeyEmplGrp>
      <RltdOrgOfficerTrstKeyEmplGrp>
        <PersonNm>DAVID P BICK</PersonNm>
        <TitleTxt>PRINCIPAL INVESTG</TitleTxt>
        <BaseCompensationFilingOrgAmt>354760</BaseCompensationFilingOrgAmt>
        <NontaxableBenefitsFilingOrgAmt>32600</NontaxableBenefitsFilingOrgAmt>
        <TotalCompensationFilingOrgAmt>387360</TotalCompensationFilingOrgAmt>
      </RltdOrgOfficerTrstKeyEmplGrp>
      <RltdOrgOfficerTrstKeyEmplGrp>
        <PersonNm>GREGORY BARSH</PersonNm>
        <TitleTxt>PRINCIPAL INVESTG</TitleTxt>
        <BaseCompensationFilingOrgAmt>342898</BaseCompensationFilingOrgAmt>
        <NontaxableBenefitsFilingOrgAmt>32600</NontaxableBenefitsFilingOrgAmt>
        <TotalCompensationFilingOrgAmt>375498</TotalCompensationFilingOrgAmt>
      </RltdOrgOfficerTrstKeyEmplGrp>
      <RltdOrgOfficerTrstKeyEmplGrp>
        <PersonNm>JEREMY SCHMUTZ</PersonNm>
        <TitleTxt>PRINCIPAL INVESTG</TitleTxt>
        <BaseCompensationFilingOrgAmt>295133</BaseCompensationFilingOrgAmt>
        <NontaxableBenefitsFilingOrgAmt>27091</NontaxableBenefitsFilingOrgAmt>
        <TotalCompensationFilingOrgAmt>322224</TotalCompensationFilingOrgAmt>
      </RltdOrgOfficerTrstKeyEmplGrp>
      <RltdOrgOfficerTrstKeyEmplGrp>
        <PersonNm>JANE GRIMWOOD</PersonNm>
        <TitleTxt>PRIN INVESTG</TitleTxt>
        <BaseCompensationFilingOrgAmt>265974</BaseCompensationFilingOrgAmt>
        <NontaxableBenefitsFilingOrgAmt>24213</NontaxableBenefitsFilingOrgAmt>
        <TotalCompensationFilingOrgAmt>290187</TotalCompensationFilingOrgAmt>
      </RltdOrgOfficerTrstKeyEmplGrp>
      <RltdOrgOfficerTrstKeyEmplGrp>
        <PersonNm>NEIL LAMB</PersonNm>
        <TitleTxt>VP OF ED. OUTREACH</TitleTxt>
        <BaseCompensationFilingOrgAmt>260002</BaseCompensationFilingOrgAmt>
        <NontaxableBenefitsFilingOrgAmt>23830</NontaxableBenefitsFilingOrgAmt>
        <TotalCompensationFilingOrgAmt>283832</TotalCompensationFilingOrgAmt>
      </RltdOrgOfficerTrstKeyEmplGrp>
      <RltdOrgOfficerTrstKeyEmplGrp>
        <PersonNm>ELIZABETH WORTHEY</PersonNm>
        <TitleTxt>PRINCIPAL INVESTIGAT</TitleTxt>
        <BaseCompensationFilingOrgAmt>249800</BaseCompensationFilingOrgAmt>
        <NontaxableBenefitsFilingOrgAmt>23779</NontaxableBenefitsFilingOrgAmt>
        <TotalCompensationFilingOrgAmt>273579</TotalCompensationFilingOrgAmt>
      </RltdOrgOfficerTrstKeyEmplGrp>
      <RltdOrgOfficerTrstKeyEmplGrp>
        <PersonNm>DEVIN ABSHER</PersonNm>
        <TitleTxt>PRINCIPAL INVESTG</TitleTxt>
        <BaseCompensationFilingOrgAmt>225018</BaseCompensationFilingOrgAmt>
        <NontaxableBenefitsFilingOrgAmt>18993</NontaxableBenefitsFilingOrgAmt>
        <TotalCompensationFilingOrgAmt>244011</TotalCompensationFilingOrgAmt>
      </RltdOrgOfficerTrstKeyEmplGrp>
      <RltdOrgOfficerTrstKeyEmplGrp>
        <PersonNm>GREGORY COOPER</PersonNm>
        <TitleTxt>PRINCIPAL INVESTIGAT</TitleTxt>
        <BaseCompensationFilingOrgAmt>200010</BaseCompensationFilingOrgAmt>
        <NontaxableBenefitsFilingOrgAmt>16806</NontaxableBenefitsFilingOrgAmt>
        <TotalCompensationFilingOrgAmt>216816</TotalCompensationFilingOrgAmt>
      </RltdOrgOfficerTrstKeyEmplGrp>
      <RltdOrgOfficerTrstKeyEmplGrp>
        <PersonNm>JIAN HAN</PersonNm>
        <TitleTxt>PRINCIPAL INVESTG</TitleTxt>
        <BaseCompensationFilingOrgAmt>184021</BaseCompensationFilingOrgAmt>
        <NontaxableBenefitsFilingOrgAmt>17115</NontaxableBenefitsFilingOrgAmt>
        <TotalCompensationFilingOrgAmt>201136</TotalCompensationFilingOrgAmt>
      </RltdOrgOfficerTrstKeyEmplGrp>
      <RltdOrgOfficerTrstKeyEmplGrp>
        <PersonNm>SARA COOPER</PersonNm>
        <TitleTxt>PRINCIPAL INVESTG</TitleTxt>
        <BaseCompensationFilingOrgAmt>173936</BaseCompensationFilingOrgAmt>
        <NontaxableBenefitsFilingOrgAmt>15287</NontaxableBenefitsFilingOrgAmt>
        <TotalCompensationFilingOrgAmt>189223</TotalCompensationFilingOrgAmt>
      </RltdOrgOfficerTrstKeyEmplGrp>
      <RltdOrgOfficerTrstKeyEmplGrp>
        <PersonNm>GREGG TYREE</PersonNm>
        <TitleTxt>DIR/OPER</TitleTxt>
        <BaseCompensationFilingOrgAmt>172135</BaseCompensationFilingOrgAmt>
        <NontaxableBenefitsFilingOrgAmt>6590</NontaxableBenefitsFilingOrgAmt>
        <TotalCompensationFilingOrgAmt>178725</TotalCompensationFilingOrgAmt>
      </RltdOrgOfficerTrstKeyEmplGrp>
      <RltdOrgOfficerTrstKeyEmplGrp>
        <PersonNm>FLORENCIA BEHN</PersonNm>
        <TitleTxt>RESEARCH AFFAIRS DIR</TitleTxt>
        <BaseCompensationFilingOrgAmt>165000</BaseCompensationFilingOrgAmt>
        <NontaxableBenefitsFilingOrgAmt>5900</NontaxableBenefitsFilingOrgAmt>
        <TotalCompensationFilingOrgAmt>170900</TotalCompensationFilingOrgAmt>
      </RltdOrgOfficerTrstKeyEmplGrp>
      <RltdOrgOfficerTrstKeyEmplGrp>
        <PersonNm>KANKSHITA SWAMINATHAN</PersonNm>
        <TitleTxt>PRINCIPAL INVESTG</TitleTxt>
        <BaseCompensationFilingOrgAmt>163470</BaseCompensationFilingOrgAmt>
        <NontaxableBenefitsFilingOrgAmt>14817</NontaxableBenefitsFilingOrgAmt>
        <TotalCompensationFilingOrgAmt>178287</TotalCompensationFilingOrgAmt>
      </RltdOrgOfficerTrstKeyEmplGrp>
    </IRS990ScheduleJ>
    <IRS990ScheduleO documentId="RetDoc7">
      <SupplementalInformationDetail>
        <FormAndLineReferenceDesc>FORM 990 - ORGANIZATION'S MISSION</FormAndLineReferenceDesc>
        <ExplanationTxt>THE PRIMARY MISSION OF THE INSTITUTE WILL BE TO USE THE INCREASINGLY POWERFUL RESEARCH TOOLS BEING DEVELOPED IN THE BIOTECHNOLOGY AREA TO BETTER UNDERSTAND THE CAUSES OF CERTAIN DISEASES AND TO APPLY THE FINDINGS OF SUCH RESEARCH TO HELP DEVELOP NEW AND MORE EFFECTIVE TREATMENTS FOR SUCH DISEASES. THE INSTITUTE'S CHARITABLE MISSION CONTEMPLATES NUMEROUS OTHER ACTIVITIES ALL OF WHICH ARE INTENDED TO HELP FURTHER BIOTECH RESEARCH IN ALABAMA.</ExplanationTxt>
      </SupplementalInformationDetail>
      <SupplementalInformationDetail>
        <FormAndLineReferenceDesc>FORM 990, PAGE 6, PART VI, LINE 11B</FormAndLineReferenceDesc>
        <ExplanationTxt>FORM 990 IS PROVIDED TO THE CFO WHO THEN DISTRIBUTES COPIES TO THE GOVERNING BODY FOR REVIEW.</ExplanationTxt>
      </SupplementalInformationDetail>
      <SupplementalInformationDetail>
        <FormAndLineReferenceDesc>FORM 990, PAGE 6, PART VI, LINE 12C</FormAndLineReferenceDesc>
        <ExplanationTxt>A CONFLICT OF INTEREST DISCLOSURE IS REVIEWED FOR ANY NEW GRANT, CONTRACT, PROPOSED PARTNERSHIP, OR COLLABORATION.</ExplanationTxt>
      </SupplementalInformationDetail>
      <SupplementalInformationDetail>
        <FormAndLineReferenceDesc>FORM 990, PAGE 6, PART VI, LINE 19</FormAndLineReferenceDesc>
        <ExplanationTxt>NO DOCUMENTS AVAILABLE TO THE PUBLIC.</ExplanationTxt>
      </SupplementalInformationDetail>
    </IRS990ScheduleO>
    <IRS990ScheduleR documentId="RetDoc8">
      <IdDisregardedEntitiesGrp>
        <DisregardedEntityName>
          <BusinessNameLine1Txt>HUDSONALPHA CLINICAL SERVICES LAB</BusinessNameLine1Txt>
        </DisregardedEntityName>
        <USAddress>
          <AddressLine1Txt>601 GENOME WAY</AddressLine1Txt>
          <CityNm>HUNTSVILLE</CityNm>
          <StateAbbreviationCd>AL</StateAbbreviationCd>
          <ZIPCd>35806</ZIPCd>
        </USAddress>
        <EIN>474553847</EIN>
        <PrimaryActivitiesTxt>SERVICES</PrimaryActivitiesTxt>
        <LegalDomicileStateCd>AL</LegalDomicileStateCd>
        <TotalIncomeAmt>114975</TotalIncomeAmt>
        <EndOfYearAssetsAmt>30642</EndOfYearAssetsAmt>
        <DirectControllingEntityName>
          <BusinessNameLine1Txt>HAIB</BusinessNameLine1Txt>
        </DirectControllingEntityName>
      </IdDisregardedEntitiesGrp>
      <IdDisregardedEntitiesGrp>
        <DisregardedEntityName>
          <BusinessNameLine1Txt>SMITH FAMILY CLINIC FOR GEOMIC</BusinessNameLine1Txt>
          <BusinessNameLine2Txt>MEDICINE LLC</BusinessNameLine2Txt>
        </DisregardedEntityName>
        <USAddress>
          <AddressLine1Txt>601 GENOME WAY</AddressLine1Txt>
          <CityNm>HUNTSVILLE</CityNm>
          <StateAbbreviationCd>AL</StateAbbreviationCd>
          <ZIPCd>35806</ZIPCd>
        </USAddress>
        <EIN>474553450</EIN>
        <PrimaryActivitiesTxt>SERVICES</PrimaryActivitiesTxt>
        <LegalDomicileStateCd>AL</LegalDomicileStateCd>
        <TotalIncomeAmt>32560</TotalIncomeAmt>
        <EndOfYearAssetsAmt>65254</EndOfYearAssetsAmt>
        <DirectControllingEntityName>
          <BusinessNameLine1Txt>HAIB</BusinessNameLine1Txt>
        </DirectControllingEntityName>
      </IdDisregardedEntitiesGrp>
      <IdRelatedTaxExemptOrgGrp>
        <DisregardedEntityName>
          <BusinessNameLine1Txt>HUDSONALPHA FOUNDATION</BusinessNameLine1Txt>
        </DisregardedEntityName>
        <USAddress>
          <AddressLine1Txt>601 GENOME WAY</AddressLine1Txt>
          <CityNm>HUNTSVILLE</CityNm>
          <StateAbbreviationCd>AL</StateAbbreviationCd>
          <ZIPCd>35806</ZIPCd>
        </USAddress>
        <EIN>272320591</EIN>
        <PrimaryActivitiesTxt>ADVANCEMEN</PrimaryActivitiesTxt>
        <LegalDomicileStateCd>AL</LegalDomicileStateCd>
        <ExemptCodeSectionTxt>501C3</ExemptCodeSectionTxt>
        <PublicCharityStatusTxt>7</PublicCharityStatusTxt>
        <DirectControllingNACd>N/A</DirectControllingNACd>
        <ControlledOrganizationInd>false</ControlledOrganizationInd>
      </IdRelatedTaxExemptOrgGrp>
      <IdRelatedOrgTxblCorpTrGrp>
        <RelatedOrganizationName>
          <BusinessNameLine1Txt>HUDSONALPHA SERVICES CORPORATION</BusinessNameLine1Txt>
        </RelatedOrganizationName>
        <USAddress>
          <AddressLine1Txt>601 GENOME WAY</AddressLine1Txt>
          <CityNm>HUNTSVILLE</CityNm>
          <StateAbbreviationCd>AL</StateAbbreviationCd>
          <ZIPCd>35806</ZIPCd>
        </USAddress>
        <EIN>823114735</EIN>
        <PrimaryActivitiesTxt>LEASING</PrimaryActivitiesTxt>
        <LegalDomicileStateCd>AL</LegalDomicileStateCd>
        <DirectControllingNACd>N/A</DirectControllingNACd>
        <EntityTypeTxt>C CORP</EntityTypeTxt>
        <ShareOfEOYAssetsAmt>41053</ShareOfEOYAssetsAmt>
        <OwnershipPct>1.00000</OwnershipPct>
        <ControlledOrganizationInd>false</ControlledOrganizationInd>
      </IdRelatedOrgTxblCorpTrGrp>
      <ReceiptOfIntAnntsRntsRyltsInd>false</ReceiptOfIntAnntsRntsRyltsInd>
      <GiftGrntOrCapContriToOthOrgInd>false</GiftGrntOrCapContriToOthOrgInd>
      <GiftGrntCapContriFromOthOrgInd>true</GiftGrntCapContriFromOthOrgInd>
      <LoansOrGuaranteesToOtherOrgInd>false</LoansOrGuaranteesToOtherOrgInd>
      <LoansOrGuaranteesFromOthOrgInd>false</LoansOrGuaranteesFromOthOrgInd>
      <DivRelatedOrganizationInd>false</DivRelatedOrganizationInd>
      <AssetSaleToOtherOrgInd>false</AssetSaleToOtherOrgInd>
      <AssetPurchaseFromOtherOrgInd>false</AssetPurchaseFromOtherOrgInd>
      <AssetExchangeInd>false</AssetExchangeInd>
      <RentalOfFacilitiesToOthOrgInd>false</RentalOfFacilitiesToOthOrgInd>
      <RentalOfFcltsFromOthOrgInd>true</RentalOfFcltsFromOthOrgInd>
      <PerformOfServicesForOthOrgInd>false</PerformOfServicesForOthOrgInd>
      <PerformOfServicesByOtherOrgInd>false</PerformOfServicesByOtherOrgInd>
      <SharingOfFacilitiesInd>true</SharingOfFacilitiesInd>
      <PaidEmployeesSharingInd>true</PaidEmployeesSharingInd>
      <ReimbursementPaidToOtherOrgInd>false</ReimbursementPaidToOtherOrgInd>
      <ReimbursementPaidByOtherOrgInd>false</ReimbursementPaidByOtherOrgInd>
      <TransferToOtherOrgInd>false</TransferToOtherOrgInd>
      <TransferFromOtherOrgInd>false</TransferFromOtherOrgInd>
      <TransactionsRelatedOrgGrp>
        <OtherOrganizationName>
          <BusinessNameLine1Txt>HUDSONALPHA FOUNDATION</BusinessNameLine1Txt>
        </OtherOrganizationName>
        <TransactionTypeTxt>C</TransactionTypeTxt>
        <InvolvedAmt>8465732</InvolvedAmt>
      </TransactionsRelatedOrgGrp>
      <TransactionsRelatedOrgGrp>
        <OtherOrganizationName>
          <BusinessNameLine1Txt>HUDSONALPHA FOUNDATION</BusinessNameLine1Txt>
        </OtherOrganizationName>
        <TransactionTypeTxt>N</TransactionTypeTxt>
      </TransactionsRelatedOrgGrp>
      <TransactionsRelatedOrgGrp>
        <OtherOrganizationName>
          <BusinessNameLine1Txt>HUDSONALPHA FOUNDATION</BusinessNameLine1Txt>
        </OtherOrganizationName>
        <TransactionTypeTxt>O</TransactionTypeTxt>
      </TransactionsRelatedOrgGrp>
      <TransactionsRelatedOrgGrp>
        <OtherOrganizationName>
          <BusinessNameLine1Txt>HUDSONALPHA SERVICES CORPORATION</BusinessNameLine1Txt>
        </OtherOrganizationName>
        <TransactionTypeTxt>K</TransactionTypeTxt>
        <InvolvedAmt>2452799</InvolvedAmt>
      </TransactionsRelatedOrgGrp>
    </IRS990ScheduleR>
  </ReturnData>
</Return>