2018-05-11T09:57:00-07:00 2017-12-31 990EZ 2017-01-01 475555752 CHAMP FOUNDATION CHAM 7278712667 2712 LITTLE ROGERS ROAD DURHAM NC 27704 Jeffrey Reynolds President 7278712667 2018-05-11 2017 2022-09-23 18:48:47Z X www.thechampfoundation.org X X 176294 X 161972 0 0 0 0 0 0 0 14220 2243 11977 0 0 0 102 174051 172500 0 0 0 0 0 1122 173622 429 239382 0 239811 239382 239811 0 0 0 0 239382 239811 0 0 239382 239811 The Champ Foundation supports research toward better treatment and a cure for diseases caused by mitochondrial DNA deletions, with an emphasis on Pearson Syndrome. These diseases are very rare; for example, there have only been around 100 cases of Pearson Syndrome described in the literature since its discovery in 1979. Current "treatments" only address symptoms as they present themselves. Therefore, The Champ Foundation seeks to fund research that speeds the development of treatment and a cure. In 2017, The Champ Foundation expanded it's research funding through our first call for grants. Our Scientific Advisory Board recommended funding for two projects. The first "CD34+ cells enriched with blood cells derived healthy mitochondria as a treatment for Pearson Syndrome" seeks to employ a novel treatment based on stem cell transplant and is being undertaken at the Sheba Medical Center in Tel Aviv. The second, "Treatments and models for diseases caused by mitochondrial deletions," is being undertaken at the University of Cambridge. We also continued our support to Boston Children's project. All three projects characterize The Champ Foundation's approach. We seek out talented researchers at excellent institutions, whose intellectual interest in mitochondrial DNA deletion disorders has been hindered by financial concerns. We believe that these diseases can be treated and cured, provided that capable researchers and clinicians are aware of the problem and allowed to pursue a solution. 260000 X 0 0 Jeffrey Reynolds President 10 0 0 0 Elizabeth Reynolds Vice President 10 0 0 0 Elizabeth Malkin Secretary 1 0 0 0 Tyler Albright Treasurer 1 0 0 0 Walker Cole Arledge Director 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 NC NY Jeffrey Reynolds 2712 LITTLE ROGERS ROAD DURHAM NC 27704 7278712667 0 0 0 0 0 0 0 0 0 0 0 NONE NONE 1 X 107586 110214 161972 379772 0 0 0 0 0 0 0 0 0 0 107586 110214 161972 379772 177194 202578 0 0 102 102 0 0 0 0 0 0 0 0 379874 0 X RESTRICTED RESTRICTED RESTRICTED RESTRICTED RESTRICTED RESTRICTED RESTRICTED RESTRICTED Form 990-EZ, Part I, Line 8 Bank Interest Form 990-EZ, Part I, Line 10 Research grants to Sheba Medical Center, Cambridge University and Boston Children's Hospital. Form 990-EZ, Part I, Line 16 PayPal and Bank fees