2018-06-11T16:47:30-05:00 2016-12-31 910189318 Moss Adams LLP 4747 Executive Drive Suite 1300 San Diego CA 92121 990 2016-03-01 811669175 Chan Zuckerberg Biohub Inc CHAN 6282003246 499 Illinois St San Francisco CA 94158 Victor Colunga Interim CFO 6282003246 2018-06-07 1 Patricia J Mayer P00188643 8586271400 2016 2022-09-23 18:48:47Z X X X Gajus Worthington 499 Illinois St San Francisco CA 94158 580779624 0 X www.czbiohub.org X 2016 CA Conduct cutting edge medical research. 7 5 9 4 0 0 580723074 0 56550 0 580779624 4800000 0 314189 0 0 1855638 6969827 573809797 581780417 4720620 577059797 X Alleviating human suffering through its mission to cure, manage, and prevent all diseases by the end of the 21st century. 0 0 5488690 4800000 As a newly formed medical research organization, Chan Zuckerberg Biohub Inc. (the "Hub"), planned research will focus on several large scale scientific problems with a multi-year lifetime, with some projects focusing on basis science and some on clinical research. In addition, the Hub expects to conduct a number of smaller research programs, the most promising of which could form the basis for large-scale scientific programs that the hub will focus on in future years. Two of the large-scale projects will be the following: 1) The cell atlas will constitute a massive human cell type, cell state and genetic interaction map several orders of magnitude larger and higher dimension than all preceding efforts in model organisms, and will initially focus on cancer, neurological and cardiovascular functions. 2) The infectious disease project will utilize a multi-pronged approach to combat infectious disease, including the rapid development and deployment of genetic testing for infectious diseases, and both drug discovery and vaccine design efforts. In addition, the hub will fund complementary and cooperative research projects through the Chan/Zuckerberg investigators program and affiliate gift program. 5488690 1 1 0 0 0 0 0 0 0 0 1 0 0 0 0 1 1 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 1 0 0 0 1 0 0 0 0 1 0 0 0 1 18 0 1 9 1 0 0 0 0 0 0 0 0 0 0 X 7 5 1 1 1 0 0 1 1 1 1 0 0 1 1 0 1 1 0 1 0 0 CA X Victor Colunga 6282003246 499 Illinois St San Francisco CA 94158 Cori Bargmann Treasurer 5.00 X X 0 0 0 Dr John Hennessy Director 5.00 X 0 0 0 Dr Joseph DeRisi Co-Chief Executive 40.00 X X 91816 0 601 Dr Priscilla Chan President, Director 5.00 X X 0 0 0 Dr Stephen Quake Co-Chief Executive 40.00 X X 91816 0 601 Mark Zuckerberg Director 5.00 X 0 0 0 Reid Hoffman Secretary 5.00 X X 0 0 0 Rakesh Mehta Treasurer (thru 10/16) 5.00 X 0 0 0 Tom Van Loben Sels Secretary (thru 10/16) 5.00 X 0 0 0 183632 0 1202 0 0 0 0 Cooley LLP 101 California Street 5th floor San Francisco CA 94111 Legal Consulting 371808 Arnold & Porter LLP 555 Twelfth Street NW Washington DC 20004 Legal Consulting 370267 Wide Center Advisors LLC PO BOX 20713 Oakland CA 94620 Operations Consulting 230690 3 580723074 371000 580723074 56550 56550 580779624 0 0 56550 4800000 4800000 207088 207088 90496 64745 25751 8238 8238 8367 6023 2344 930172 471606 458566 66044 66044 681229 47140 634089 1639 1639 3348 3348 91379 91379 821 821 1564 1564 48163 48163 Recruiting 22537 22537 Lab Supplies 7537 7537 Payroll Processing 1150 260 890 Credit Card Fees 30 30 25 25 6969827 5488690 1481137 0 1742450 57087550 521973074 977343 0 0 977343 0 581780417 4720620 0 4720620 X 55086723 521973074 0 577059797 0 581780417 573809797 3250000 0 X 0 1 X 1 0 X affiliated hospitals of Stanford Stanford CA affiliated hospitals of UCSF San Francisco CA Schedule A THE HUB IS IN THE PROCESS OF LAUNCHING ITS RESEARCH ACTIVITIES. IT IS A NEWLY-CREATED ORGANIZATION AND BELIEVES IT WILL BE CONSIDERED TO BE CONTINUOUSLY ENGAGED IN THE ACTIVE CONDUCT OF MEDICAL RESEARCH IN CONJUNCTION WITH A HOSPITAL AND IT REASONABLY EXPECTS TO SATISFY THE ASSET TEST OR ENDOWMENT TEST BY THE END OF ITS ORGANIZATIONAL PERIOD OF UP TO THREE YEARS. RESTRICTED RESTRICTED RESTRICTED RESTRICTED RESTRICTED RESTRICTED RESTRICTED RESTRICTED 977343 977343 977343 X 584029624 3250000 3250000 580779624 0 580779624 6969827 0 6969827 0 6969827 Part X, Line 2: The Biohub, is exempt from income taxes under Section 501(c)(3) of the Internal Revenue Code and Section 23701d of the California Revenue and Taxation Code. The Organization has no unrecognized tax benefits or liabilities as of December 31, 2016. 1 Stanford 3145 Porter Drive palo Alto CA 94304 941156365 501(C)(3) 2800000 Scientific and Medical Research UCSF UCSF PO BOX 0248 San Francisco CA 94143 946036493 501(C)(3) 2000000 Scientific and Medical Research 2 Part I, Line 2: The HUB will obligate the use of the gift funds only for the purpose for which the HUB makes the award. The HUB will require periodic written reports concerning the use of the gift as appropriate and retain for the HUB the right to withhold or recover fund in cases of misuse as appropriate. from time to time, the HUB will make discretionary gifts to 501(c)(3) organizations without the need for a written proposal. Dr Stephen Quake Co-Chief Executive & Board Member of organization 500000 Award to conduct research Award provided to Stanford University to support research lab of Dr. Quake Dr Joseph Derisi Co-Chief Executive & Board Member of organization 1000000 Award to conduct research Award provided to UCSF to support research lab of Dr. Derisi X Furniture & Fixtures 182 371000 fair market value 0 0 0 Form 990, Part VI, Section A, line 2 DR. CHAN (PRESIDENT, DIRECTOR) AND MR. ZUCKERBERG (DIRECTOR) HAVE A FAMILY RELATIONSHIP. APERCEN PARTNERS LLC, IN WHICH TOM VAN LOBEN SELS (SECRETARY) HAS MORE THAN A 35% OWNERSHIP INTEREST, HAS A BUSINESS RELATIONSHIP WITH DR. CHAN, MR. ZUCKERBERG, AND REID HOFFMAN. CORI BARGMANN AND MR. ZUCKERBERG HAVE A BUSINESS RELATIONSHIP. Form 990, Part VI, Section A, line 3 An unrelated party, Wide Center Advisors, LLC, provides operational consulting services to the HUB, including, but not limited to, support of the organization's financial, budgeting, staffing, facilities, and professional services capacities. Form 990, Part VI, Section A, line 4 THE BYLAWS OF THE HUB WERE AMENDED TO INCLUDE THE FOLLOWING SIGNIFICANT CHANGES: THE MEMBER OF DIRECTORS SHALL BE TWO, WHICH MAY BE INCREASED OR DECREASED. TWO DIRECTORS OF THE BOARD SHALL BE DESIGNATED BY THE CHAN ZUCKERBERG INITIATIVE, LLC AND SUCH APPOINTED TWO DIRECTORS (DESIGNATED DIRECTORS) ARE REQUIRED TO NOTIFY THE ORGANIZATION IF THERE IS A SUCCESSOR DESIGNATOR DUE TO MERGER, REORGANIZATION, OR SALE OF THE DESIGNATOR'S COMPANY. IF THE DESIGNATOR CEASES TO EXIST AND THERE IS NO SUCCESSOR, THE PROVISION OF THE BYLAWS RELATING TO THE DESIGNATED DIRECTORS SHALL NO LONGER BE IN EFFECT. DESIGNATED DIRECTOR APPROVAL IS REQUIRED FOR THE SIGNIFICANT ITEMS LISTED BELOW: -CHANGING THE NATURE OR SCOPE OF THE MISSION. -CHANGING, SELLING OR LICENSING THE NAME OF THE CORPORATION. -APPROVING OR PERMITTING THE USE OR OTHER EXPLOITATION OF THE NAME OF THE CORPORATION BY ANY PARTY, OTHER THAN THE DESIGNATOR, ANY AFFILIATE OR AFFILIATED ENTITY OF THE DESIGNATOR AND, SOLELY IN CONNECTION WITH THE CORPORATION'S ACTIVITIES IN FURTHERANCE OF THE MISSION. -APPOINTING, ELECTING OR REMOVING ANY DIRECTOR OF THE CORPORATION AND FILLING OF ANY VACANCY OF THE BOARD. -INCREASING OR DECREASING THE NUMBER OF DIRECTOR SEATS ON THE BOARD. -APPOINTING, ELECTING OR REMOVING THE CHAIRPERSON. -ACCEPTING CONTRIBUTIONS FROM ANY PARTY OTHER THAN FROM THE DESIGNATOR, ANY AFFILIATE OR AFFILIATED ENTITY OF THE DESIGNATOR, OR ANY DONOR ADVISED FUND IN WHICH THE DESIGNATION OR AFFILIATE HAVE ADVISORY PRIVILEGES. OTHER PARTY FUNDING CAN BE ACCEPTED IF THE DESIGNATOR FUNDING SOURCE HAS A MATERIAL BREACH AND ADDITIONAL FUNDING IS NEEDED. -APPROVAL OR EFFECTING OF A MATERIAL SALE OF ASSETS OR MERGER OF THE ORGANIZATION OR CONVERSION INTO ANOTHER FORM OF ENTITY. -APPROVAL OF ACTION CAUSING CHANGE FROM EXEMPT STATUS UNDER 501(A) OF THE CODE. -APPROVAL FOR COMMENCING BANKRUPTCY, INSOLVENCY OR RELIEF OF DEBTORS. -APPROVAL, PERMITTING OR EFFECTING ANY TRANSACTION TO LIQUIDATE, WIND UP OR DISSOLVE THE CORPORATION. -APPROVAL FOR CHANGE TO ORGANIZATION DOCUMENTS. Form 990, Part VI, Section A, line 7a THE CHAN ZUCKERBERG INIATIVE, LLC DESIGNATES TWO BOARD OF DIRECTORS (DESIGNATED DIRECTORS). SUCH DESIGNATED DIRECTORS APPROVE THE APPOINTING, ELECTING, OR REMOVING OF ANY DIRECTOR OF THE ORGANIZATION INCLUDING THE FILLING OF ANY VACANCY OF THE BOARD. Form 990, Part VI, Section A, line 7b GOVERNANCE DECISIONS ARE SUBJECT TO APPROVAL BY THE TWO DESIGNATED DIRECTORS INCLUDING: -CHANGING THE NATURE OR SCOPE OF THE MISSION. -CHANGING, SELLING OR LICENSING THE NAME OF THE CORPORATION. -APPROVING OR PERMITTING THE USE OR OTHER EXPLOITATION OF THE NAME OF THE CORPORATION BY ANY PARTY, OTHER THAN THE DESIGNATOR, ANY AFFILIATE OR AFFILIATED ENTITY OF THE DESIGNATOR AND, SOLELY IN CONNECTION WITH THE CORPORATION'S ACTIVITIES IN FURTHERANCE OF THE MISSION. -APPOINTING, ELECTING OR REMOVING ANY DIRECTOR OF THE CORPORATION AND FILLING OF ANY VACANCY OF THE BOARD. -INCREASING OR DECREASING THE NUMBER OF DIRECTOR SEATS ON THE BOARD. -APPOINTING, ELECTING OR REMOVING THE CHAIRPERSON. -ACCEPTING CONTRIBUTIONS FROM ANY PARTY OTHER THAN FROM THE DESIGNATOR, ANY AFFILIATE OR AFFILIATED ENTITY OF THE DESIGNATOR, OR ANY DONOR ADVISED FUND IN WHICH THE DESIGNATION OR AFFILIATE HAVE ADVISORY PRIVILEGES. OTHER PARTY FUNDING CAN BE ACCEPTED IF THE DESIGNATOR FUNDING SOURCE HAS A MATERIAL BREACH AND ADDITIONAL FUNDING IS NEEDED. -APPROVAL OR EFFECTING OF A MATERIAL SALE OF ASSETS OR MERGER OF THE ORGANIZATION OR CONVERSION INTO ANOTHER FORM OF ENTITY. -APPROVAL OF ACTION CAUSING CHANGE FROM EXEMPT STATUS UNDER 501(A) OF THE CODE. -APPROVAL FOR COMMENCING BANKRUPTCY, INSOLVENCY OR RELIEF OF DEBTORS. -APPROVAL, PERMITTING OR EFFECTING ANY TRANSACTION TO LIQUIDATE, WIND UP OR DISSOLVE THE CORPORATION. -APPROVAL FOR CHANGE TO ORGANIZATION DOCUMENTS. Form 990, Part VI, Section B, line 11b The Form 990 is prepared by our tax consultants. The Draft is reviewed by the interim CFO of the organization. The Form 990 is then made available to the rest of the board prior to the 990 being filed. Form 990, Part VI, Section B, line 12c OFFICERS AND DIRECTORS SIGN A CONFLICT OF INTEREST AFFIDAVIT UPON APPOINTMENT. IF A TRANSACTION ARISES WHERE THERE IS A CONFLICT OF INTEREST, THE PERSON WITH SUCH CONFLICT IS NOT ALLOWED TO VOTE ON THE TRANSACTION. Form 990, Part VI, Section B, line 15a THE BOARD OF DIRECTORS AND EXECUTIVE COMMITTEE OF THE BOARD REVIEW AND APPROVE THE COMPENSATION OF THE ORGANIZATION'S CO-Chief Executives. THE PROCESS INCLUDES A REVIEW OF THE COMPENSATION AGAINST CURRENT COMPARABILITY DATA (SURVEY OR STUDY) PREPARED BY AN INDEPENDENT COMPENSATION CONSULTANT. THE PROCESS IS DOCUMENTED AND WAS LAST COMPLETED SEPTEMBER 2016. Form 990, Part VI, Section C, line 19 THE HUB'S GOVERNING DOCUMENTS, CONFLICT OF INTEREST POLICY, AND FINANCIAL STATEMENTS WILL BE FURNISHED TO THE PUBLIC UPON REQUEST. The Chan Zuckerberg Advocacy 314 Lytton Avenue Suite 200 Palo Alto CA 94301 813742328 SOCIAL WElfare CA 501(c)(4) n/a N/A 0 The Chan Zuckerberg Foundation 314 Lytton Avenue Suite 200 Palo Alto CA 94301 455002209 Grantmaking CA 501(c)(3) PF N/A 0 The Primary School 314 Lytton Avenue Suite 200 Palo Alto CA 94301 364858582 Social Welfare CA 501(c)(4) N/A N/A 0 The Primary school - East Palo Alto 314 Lytton Avenue Suite 200 Palo Alto CA 94301 473334579 education CA 501(c)(3) Line 2 N/A 0 Openness Foundation 314 Lytton Avenue Suite 200 Palo Alto CA 94301 270889149 Grantmaking CA 501(c)(3) N/A N/A 0 facebook Inc 1601 Willow Road Menlo Park CA 94025 social media service company DE N/A C 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0