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        <FormAndLineReferenceDesc>Part X : FIN48 Footnote</FormAndLineReferenceDesc>
        <ExplanationTxt>The Organization is exempt from income tax under Section 501(c)(3) of the Internal Revenue Code and is classified as other than a private foundation. Management has reviewed all tax positions recognized in previously filed tax returns and those expected to be taken in future tax returns. As of December 31, 2016, the Organization had no amounts related to unrecognized income tax benefits and no amounts related to accrued interest and penalties. The Organization does not anticipate any significant changes to unrecognized income tax benefits over the next year.</ExplanationTxt>
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        <ExplanationTxt>The award recipient must submit a final written progress report to the CIS, including disposition of funds that is reviewed by the Executive Director. It is also expected the recipient will present the final results of his/her research at a future CIS Annual Meeting.</ExplanationTxt>
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      <SupplementalInformationDetail>
        <FormAndLineReferenceDesc>Form 990, Part VI, Line 4: Description of Significant Changes to Organizational Documents</FormAndLineReferenceDesc>
        <ExplanationTxt>Summary of 2016 CIS Bylaws changes1. Article III, Section 3.1, Numbera. The following sentences were updated:The Editor of the Journal of Clinical Immunology, the official journal of the Clinical Immunology Society serves in a non-voting capacity.b. The number of years a Councilor serves changed from 6 to 3 years.c. The number of additional Councilors changed from five to two, with a term change from three to two.d. The following sentence was removed:One International Councilor may be appointed by the elected Council for a term not to exceed three years.2. Article III, Section 3.3, Terms of Officea. The term of a Councilor was changed from six years to three years.b. The following sentence was added:The President-Elect is elected biennially, serves a two-year term and ascends to the position of President. Only those individuals who have previously served on the Council are eligible to run for the office of President-Elect. The President serves a two-year term. The Immediate Past President serves a two-year term.c. The following sentence was removed:In the fourth year of the term of office, the Councilor shall become President-Elect, in the fifth year, President and in the sixth year, Immediate Past President.d. The following in bold was added to the sentence:The Secretary-Treasurer shall be elected for four years and may serve successive terms as requested and approved by the Council.3. Article VIII: BylawsThe following two sentences in bold were added:A change in the Bylaws shall require a two-thirds majority of the votes cast by the members at the Annual Business Meeting or two-thirds majority of the votes cast by members electronically.Affirmative votes of a two-thirds majority of the members attending the Annual Business Meeting or voting electronically shall be required for adoption of the amendment.</ExplanationTxt>
      </SupplementalInformationDetail>
      <SupplementalInformationDetail>
        <FormAndLineReferenceDesc>Form 990, Part VI, Line 6: Explanation of Classes of Members or Shareholder</FormAndLineReferenceDesc>
        <ExplanationTxt>Regular membership is open to individuals who are engaged in research in the area of clinical immunology or have contributed to or are engaged in the practice of clinical immunology; have an MD, DO, PhD or equivalent academic degree; have made scholarly contributions as defined by the Council; are active, bona fide representatives of the international scientific community with a specialty or interest in a field related to clinical immunology. Associate membership is open to individuals who hold a Bachelors, Masters, RN or equivalent degree with a demonstrated interest in clinical immunology. Trainee membership is open to individuals who are enrolled in academic programs awarding, and are candidate for MD, DO, PhD, or equivalent degree, with a demonstrated interest in clinical immunology; are participating in post-doctoral or clinical fellowship, or residency programs. Emeritus membership is open to those individuals who have attained the age of 65 years and have been a Regular member for five years or longer.</ExplanationTxt>
      </SupplementalInformationDetail>
      <SupplementalInformationDetail>
        <FormAndLineReferenceDesc>Form 990, Part VI, Line 7a: How Members or Shareholders Elect Governing Body</FormAndLineReferenceDesc>
        <ExplanationTxt>The voting membership elects the Councilors prior to the Annual Business Meeting. The voting membership includes regular members in good standing. Associate, Trainee and Emeritus members do not have voting rights.</ExplanationTxt>
      </SupplementalInformationDetail>
      <SupplementalInformationDetail>
        <FormAndLineReferenceDesc>Form 990, Part VI, Line 7b: Describe Decisions of Governing Body Approval by Members or Shareholders</FormAndLineReferenceDesc>
        <ExplanationTxt>The voting membership is entitled to vote on all matters to be voted on by members of the Society. Any matter to be decided by a vote of the members shall be decided by majority vote of members present in person or by proxy at a meeting of members.</ExplanationTxt>
      </SupplementalInformationDetail>
      <SupplementalInformationDetail>
        <FormAndLineReferenceDesc>Form 990, Part VI, Line 11b: Form 990 Review Process</FormAndLineReferenceDesc>
        <ExplanationTxt>The completed form 990 and all applicable schedules is distributed to the council for review and approval. Once approved, the form is signed by a selected officer and filed with the IRS.</ExplanationTxt>
      </SupplementalInformationDetail>
      <SupplementalInformationDetail>
        <FormAndLineReferenceDesc>Form 990, Part VI, Line 12c: Explanation of Monitoring and Enforcement of Conflicts</FormAndLineReferenceDesc>
        <ExplanationTxt>All council members are covered under the policy. The Executive committee has the final review/determination of whether a conflict exists. The individual with a conflict is limited from decision making regarding the transaction where the conflict exists.</ExplanationTxt>
      </SupplementalInformationDetail>
      <SupplementalInformationDetail>
        <FormAndLineReferenceDesc>Form 990, Part VI, Line 15a: Compensation Review &amp; Approval Process - CEO, Top Management</FormAndLineReferenceDesc>
        <ExplanationTxt>CIS is managed by Executive Director, Inc., a for-profit management company. CIS had no official employees because all staff assigned to CIS are employees of the management company. CIS also does not compensate Councilors or other top officials. CIS also doesn't have anyone who fits the definition of a Key Employees. CIS contracts with Executive Director, Inc. to provide office facilities, management, record keeping, accounting, storage, other significant services, plus related overhead costs.</ExplanationTxt>
      </SupplementalInformationDetail>
      <SupplementalInformationDetail>
        <FormAndLineReferenceDesc>Form 990, Part VI, Line 15b: Compensation Review and Approval Process for Officers and Key Employees</FormAndLineReferenceDesc>
        <ExplanationTxt>CIS is managed by Executive Director, Inc., a for-profit management company. CIS had no official employees because all staff assigned to CIS are employees of the management company. CIS also does not compensate Councilors or other top officials. CIS also doesn't have anyone who fits the definition of a Key Employees. CIS contracts with Executive Director, Inc. to provide office facilities, management, record keeping, accounting, storage, other significant services, plus related overhead costs.</ExplanationTxt>
      </SupplementalInformationDetail>
      <SupplementalInformationDetail>
        <FormAndLineReferenceDesc>Form 990, Part VI, Line 19: Other Organization Documents Publicly Available</FormAndLineReferenceDesc>
        <ExplanationTxt>CIS makes its governing documents, conflict of interest policy, and Form 990 available for public inspection upon request. All such requests should be in writing and accompanied by a $20 reproduction and handling charge if a print copy is requested. Members of the council receiving and inquiry must advise staff of the request within a reasonable time after the inquiry is received.</ExplanationTxt>
      </SupplementalInformationDetail>
    </IRS990ScheduleO>
  </ReturnData>
</Return>