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        <ProgramServices>5081705</ProgramServices>
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      <CompCurrentOfficersDirectors>
        <Total>7434240</Total>
        <ProgramServices>3380953</ProgramServices>
        <ManagementAndGeneral>3542340</ManagementAndGeneral>
        <Fundraising>510947</Fundraising>
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        <ProgramServices>140826766</ProgramServices>
        <ManagementAndGeneral>32204035</ManagementAndGeneral>
        <Fundraising>4658412</Fundraising>
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        <ProgramServices>10465841</ProgramServices>
        <ManagementAndGeneral>2180360</ManagementAndGeneral>
        <Fundraising>318722</Fundraising>
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        <ProgramServices>13929846</ProgramServices>
        <ManagementAndGeneral>2904998</ManagementAndGeneral>
        <Fundraising>436873</Fundraising>
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        <ProgramServices>10637292</ProgramServices>
        <ManagementAndGeneral>2447585</ManagementAndGeneral>
        <Fundraising>360316</Fundraising>
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      <FeesForServicesLegal>
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        <ProgramServices>16371</ProgramServices>
        <ManagementAndGeneral>1753741</ManagementAndGeneral>
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      <FeesForServicesAccounting>
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        <ManagementAndGeneral>238401</ManagementAndGeneral>
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        <ManagementAndGeneral>114000</ManagementAndGeneral>
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        <Fundraising>384103</Fundraising>
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      <FeesForServicesInvstMgmntFees>
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        <ProgramServices>229809</ProgramServices>
        <ManagementAndGeneral>655521</ManagementAndGeneral>
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      <FeesForServicesOther>
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        <ProgramServices>8926941</ProgramServices>
        <ManagementAndGeneral>14835484</ManagementAndGeneral>
        <Fundraising>985943</Fundraising>
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      <Advertising>
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        <ManagementAndGeneral>659432</ManagementAndGeneral>
        <Fundraising>427556</Fundraising>
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        <ProgramServices>2037845</ProgramServices>
        <ManagementAndGeneral>2858760</ManagementAndGeneral>
        <Fundraising>79589</Fundraising>
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      <InformationTechnology>
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        <ManagementAndGeneral>2543418</ManagementAndGeneral>
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      <Occupancy>
        <Total>8303573</Total>
        <ProgramServices>330022</ProgramServices>
        <ManagementAndGeneral>7973551</ManagementAndGeneral>
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      <Travel>
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        <ProgramServices>3534010</ProgramServices>
        <ManagementAndGeneral>444256</ManagementAndGeneral>
        <Fundraising>110014</Fundraising>
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      <ConferencesMeetings>
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        <ProgramServices>370937</ProgramServices>
        <ManagementAndGeneral>148660</ManagementAndGeneral>
        <Fundraising>24758</Fundraising>
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      <Interest>
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        <ProgramServices>16133072</ProgramServices>
        <ManagementAndGeneral>1545262</ManagementAndGeneral>
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        <Total>27365095</Total>
        <ProgramServices>21689143</ProgramServices>
        <ManagementAndGeneral>5675952</ManagementAndGeneral>
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      <Insurance>
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        <ManagementAndGeneral>1651544</ManagementAndGeneral>
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      <OtherExpenses>
        <Description>RESEARCH SUPPLIES</Description>
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        <ProgramServices>20606821</ProgramServices>
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      <OtherExpenses>
        <Description>EQUIP. RENT &amp; MAINT.</Description>
        <Total>5393035</Total>
        <ProgramServices>2363050</ProgramServices>
        <ManagementAndGeneral>2988904</ManagementAndGeneral>
        <Fundraising>41081</Fundraising>
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      <OtherExpenses>
        <Description>DONATED AUCTION ITEMS</Description>
        <Total>533405</Total>
        <Fundraising>533405</Fundraising>
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      <OtherExpenses>
        <Description>ALLOC OF INDIRECT COSTS</Description>
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        <ProgramServices>69826182</ProgramServices>
        <ManagementAndGeneral>-69826182</ManagementAndGeneral>
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      <AllOtherExpenses>
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        <ProgramServices>5675292</ProgramServices>
        <ManagementAndGeneral>94248</ManagementAndGeneral>
        <Fundraising>362034</Fundraising>
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      <TotalFunctionalExpenses>
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        <ProgramServices>400904266</ProgramServices>
        <ManagementAndGeneral>17634270</ManagementAndGeneral>
        <Fundraising>9233753</Fundraising>
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        <EOY>3875</EOY>
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        <EOY>25866702</EOY>
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        <EOY>22782699</EOY>
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        <EOY>488124</EOY>
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        <EOY>235740017</EOY>
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      <TotalLiabNetAssetsFundBalances>
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        <EOY>698564950</EOY>
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      <ReconcilationRevenueExpenses>-14418473</ReconcilationRevenueExpenses>
      <ReconciliationUnrealizedInvest>22580509</ReconciliationUnrealizedInvest>
      <ReconcilationPriorAdjustment>-57000</ReconcilationPriorAdjustment>
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      <MethodOfAccountingAccrual>X</MethodOfAccountingAccrual>
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        <FinancialStatementConsolidated>X</FinancialStatementConsolidated>
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      <FederalGrantAuditPerformed>1</FederalGrantAuditPerformed>
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        <CurrentTaxYearMinus1Year>369203443</CurrentTaxYearMinus1Year>
        <CurrentTaxYear>348221551</CurrentTaxYear>
        <Total>1760642520</Total>
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      <Total170>
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        <CurrentTaxYear>12350746</CurrentTaxYear>
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      <GrossReceiptsFromAdmissionsEtc>244496518</GrossReceiptsFromAdmissionsEtc>
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      <ThirtyThreePercntTestsCY170>X</ThirtyThreePercntTestsCY170>
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        <CurrentYearMinus1>250000</CurrentYearMinus1>
        <CurrentYear>250000</CurrentYear>
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    <IRS990ScheduleD documentId="RetDoc1039900001">
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        <CollectionUsedForOtherPurposes>X</CollectionUsedForOtherPurposes>
        <DescriptionOfOtherPurposes>DONOR RESTRICTION</DescriptionOfOtherPurposes>
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      <EndowmentsHeldByRelatedOrgs>0</EndowmentsHeldByRelatedOrgs>
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      <OtherSecurities>
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      <OtherSecurities>
        <Description>ASSET BACKED SECURITIES</Description>
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      <OtherSecurities>
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        <MethodOfValuation>C</MethodOfValuation>
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      <OtherSecurities>
        <Description>LIMITED PARTNERSHIPS</Description>
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        <MethodOfValuation>C</MethodOfValuation>
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      <OtherSecurities>
        <Description>IKARIA STOCK</Description>
        <BookValue>5748055</BookValue>
        <MethodOfValuation>C</MethodOfValuation>
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      <InvestmentsProgramRelated>
        <Description>INVESTMENT IN SEATTLE CANCER CARE ALLIANCE</Description>
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        <MethodOfValuation>C</MethodOfValuation>
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      <TotalOfBookValueProgramRelated>84837764</TotalOfBookValueProgramRelated>
      <OtherLiabilities>
        <Description>DEFERRED CREDIT ON CASH FLOW HEDGES</Description>
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      <TotalOfAmounts>30234945</TotalOfAmounts>
      <Form990ScheduleDPartXIII>
        <ReturnReference>PART III, LINE 4:</ReturnReference>
        <Explanation>IN JANUARY 2010, THE QTIP TRUST OF THE 1993 KULLMAN FAMILY TRUST DONATED TO THE CENTER A COLLECTION OF FORTY BLACK AND WHITE PHOTOGRAPHS WHICH HAD AN APPRAISED VALUE OF $710,646 AT THE TIME OF THE DONATION. THE ARTWORK DONATION AGREEMENT REQUIRES THE CENTER TO DISPLAY THE ARTWORK AS A COLLECTION AT ITS MAIN CAMPUS IN SEATTLE, WASHINGTON FOR AT LEAST TWENTY YEARS. THE ARTWORK DONATION AGREEMENT STATES THAT "THE CENTER SHALL HAVE THE RIGHT TO USE AND DISPLAY THE ARTWORK IN THE MANNER THAT BEST SERVES THE INTEREST OF THE CENTER." AT THE END OF THE REQUIRED TWENTY YEAR DISPLAY PERIOD, THE CENTER WILL DETERMINE IF OPPORTUNITIES EXIST THAT MAY ALLOW THE VALUE OF THE DONATED ARTWORK TO FUND THE CENTER'S RESEARCH.</Explanation>
      </Form990ScheduleDPartXIII>
      <Form990ScheduleDPartXIII>
        <Identifier>DESCRIPTION OF INTENDED USE OF ENDOWMENT FUNDS:</Identifier>
        <ReturnReference>PART V, LINE 4:</ReturnReference>
        <Explanation>THE CENTER'S SPENDING POLICY FOR ENDOWMENT FUNDS IS TO APPROPRIATE FOR DISTRIBUTION EACH YEAR 5% OF THE ENDOWMENT FUND'S AVERAGE FAIR VALUE OVER THE PRIOR THREE YEARS, PROVIDED THAT THE FAIR VALUE OF THE ENDOWMENT FUND EXCEEDS THE CORPUS. FOR A PORTION OF THE CENTER'S BOARD-DESIGNATED INVESTMENTS, THE CENTER DOES NOT APPROPRIATE FOR DISTRIBUTION ANY AMOUNT OF INVESTMENT RETURN AS ALL OF THE RETURN EARNED IS HELD TO GROW THE FUND FOR FUTURE REPAYMENT OF LONG-TERM DEBT. FOR THE REMAINING BOARD DESIGNATED INVESTMENTS, THE CENTER MAKES ALL INVESTMENT RETURN AVAILABLE FOR EXPENDITURE ON PROGRAMMATIC INITIATIVES. IN ESTABLISHING THESE POLICIES, THE CENTER CONSIDERED THE LONG-TERM EXPECTED RETURNS ON ITS ENDOWMENT AND BOARD-DESIGNATED INVESTMENTS.</Explanation>
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        <NumberOfEmployees>0</NumberOfEmployees>
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      <GrantsToOrgsOutsideUS>
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        <ReturnReference>SCHEDULE G, PART I, LINE 2B, LIST OF TEN HIGHEST PAID FUNDRAISERS:</ReturnReference>
        <Explanation>(I) NAME OF FUNDRAISER: GRIZZARD COMMUNICATIONS (I) ADDRESS OF FUNDRAISER: 229 PEACHTREE STREET NE, SUITE 1400, ATLANTA, GA 30303</Explanation>
      </Form990ScheduleGPartIV>
    </IRS990ScheduleG>
    <IRS990ScheduleI documentId="RetDoc1041900001">
      <RecordsMaintained>1</RecordsMaintained>
      <RecipientTable>
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          <AddressLine1>800 EAST COMMERCE RD SUITE 203</AddressLine1>
          <City>HARAHAN</City>
          <State>LA</State>
          <ZIPCode>70123</ZIPCode>
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      <RecipientTable>
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          <BusinessNameLine1>AIDS RESEARCH ALLIANCE OF AMERICA</BusinessNameLine1>
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        <AddressUS>
          <AddressLine1>1400 S GRAND AVE SUITE 701</AddressLine1>
          <City>LOS ANGELES</City>
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      <RecipientTable>
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          <State>MA</State>
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        <EINOfRecipient>042790311</EINOfRecipient>
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      <RecipientTable>
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          <State>CA</State>
          <ZIPCode>910103012</ZIPCode>
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        <EINOfRecipient>953432210</EINOfRecipient>
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      <RecipientTable>
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          <BusinessNameLine1>BECKMAN RESEARCH INSTITUTE</BusinessNameLine1>
        </RecipientNameBusiness>
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          <AddressLine1>JOSIE SIRA GRANT ACCOUNTING 1500</AddressLine1>
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          <City>DUARTE</City>
          <State>CA</State>
          <ZIPCode>91010</ZIPCode>
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        <EINOfRecipient>953432210</EINOfRecipient>
        <IRCSection>501(C)(3)</IRCSection>
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        <DescriptionOfNonCashAssistance>N/A</DescriptionOfNonCashAssistance>
        <PurposeOfGrant>PUBLIC HEALTH SCIENCES</PurposeOfGrant>
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      <RecipientTable>
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          <City>DUARTE</City>
          <State>CA</State>
          <ZIPCode>91010</ZIPCode>
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          <AddressLine1>1201 NINTH AVE</AddressLine1>
          <City>SEATTLE</City>
          <State>WA</State>
          <ZIPCode>98101</ZIPCode>
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      <RecipientTable>
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      <RecipientTable>
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          <State>CA</State>
          <ZIPCode>941444253</ZIPCode>
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        <PurposeOfGrant>PUBLIC HEALTH SCIENCES</PurposeOfGrant>
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      <RecipientTable>
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          <BusinessNameLine1>BOARD OF TRUSTEES UNIVERSITY OF ILLINOIS</BusinessNameLine1>
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          <State>IL</State>
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        <EINOfRecipient>376000511</EINOfRecipient>
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      <RecipientTable>
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          <City>BOSTON</City>
          <State>MA</State>
          <ZIPCode>022413887</ZIPCode>
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      <RecipientTable>
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      <RecipientTable>
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      <RecipientTable>
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      <RecipientTable>
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      <RecipientTable>
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      <RecipientTable>
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      <RecipientTable>
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      <RecipientTable>
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        <AddressUS>
          <AddressLine1>6500 WILSHIRE BLVD SUITE 1150</AddressLine1>
          <City>LOS ANGELES</City>
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        <DescriptionOfNonCashAssistance>N/A</DescriptionOfNonCashAssistance>
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      <RecipientTable>
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        <DescriptionOfNonCashAssistance>N/A</DescriptionOfNonCashAssistance>
        <PurposeOfGrant>PUBLIC HEALTH SCIENCES</PurposeOfGrant>
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          <BusinessNameLine1>CENTER FOR MEDICAL TECHNOLOGY POLICY</BusinessNameLine1>
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        <AddressUS>
          <AddressLine1>WORLD TRADE CENTER BALTIMORE 401</AddressLine1>
          <AddressLine2>EAST PRATT STREET SUITE 631</AddressLine2>
          <City>BALTIMORE</City>
          <State>MD</State>
          <ZIPCode>21202</ZIPCode>
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        <EINOfRecipient>261409553</EINOfRecipient>
        <IRCSection>501(C)(3)</IRCSection>
        <AmountOfCashGrant>23121</AmountOfCashGrant>
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        <MethodOfValuation>N/A</MethodOfValuation>
        <DescriptionOfNonCashAssistance>N/A</DescriptionOfNonCashAssistance>
        <PurposeOfGrant>PUBLIC HEALTH SCIENCES</PurposeOfGrant>
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      <RecipientTable>
        <RecipientNameBusiness>
          <BusinessNameLine1>CHILDREN'S HOSPITAL MEDICAL CENTER DBA</BusinessNameLine1>
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          <AddressLine1>ACCOUNTING OFFICE MLC4900 3333</AddressLine1>
          <AddressLine2>BURNET AVENUE</AddressLine2>
          <City>CINCINNATI</City>
          <State>OH</State>
          <ZIPCode>452293039</ZIPCode>
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        <EINOfRecipient>310833936</EINOfRecipient>
        <IRCSection>501(C)(3)</IRCSection>
        <AmountOfCashGrant>73250</AmountOfCashGrant>
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        <MethodOfValuation>N/A</MethodOfValuation>
        <DescriptionOfNonCashAssistance>N/A</DescriptionOfNonCashAssistance>
        <PurposeOfGrant>CLINICAL RESEARCH</PurposeOfGrant>
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      <RecipientTable>
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          <BusinessNameLine1>CITY AND COUNTY OF SAN FRANCISCO</BusinessNameLine1>
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        <AddressUS>
          <AddressLine1>1380 HOWARD ST RM 411</AddressLine1>
          <City>SAN FRANCISCO</City>
          <State>CA</State>
          <ZIPCode>941032614</ZIPCode>
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        <EINOfRecipient>946000417</EINOfRecipient>
        <IRCSection>GOVERNMENT</IRCSection>
        <AmountOfCashGrant>140614</AmountOfCashGrant>
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        <MethodOfValuation>N/A</MethodOfValuation>
        <DescriptionOfNonCashAssistance>N/A</DescriptionOfNonCashAssistance>
        <PurposeOfGrant>VACCINE AND INFECTIOUS DISEASE</PurposeOfGrant>
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          <BusinessNameLine1>CITY OF HOUSTON</BusinessNameLine1>
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          <AddressLine1>7TH FLOOR 8000 N STADIUM DR</AddressLine1>
          <City>HOUSTON</City>
          <State>TX</State>
          <ZIPCode>770541823</ZIPCode>
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        <EINOfRecipient>746001164</EINOfRecipient>
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        <AmountOfCashGrant>30446</AmountOfCashGrant>
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        <DescriptionOfNonCashAssistance>N/A</DescriptionOfNonCashAssistance>
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          <BusinessNameLine1>CITY OF PHILADELPHIA</BusinessNameLine1>
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        <AddressUS>
          <AddressLine1>1401 JOHN KENNEDY BLVD SUITE 1380</AddressLine1>
          <City>PHILADELPHIA</City>
          <State>PA</State>
          <ZIPCode>19102</ZIPCode>
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        <EINOfRecipient>236003047</EINOfRecipient>
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        <AmountOfCashGrant>61309</AmountOfCashGrant>
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        <MethodOfValuation>N/A</MethodOfValuation>
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        <PurposeOfGrant>VACCINE AND INFECTIOUS DISEASE</PurposeOfGrant>
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          <BusinessNameLine1>CLEVELAND CLINIC FOUNDATION</BusinessNameLine1>
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          <AddressLine1>PO BOX 931562</AddressLine1>
          <City>CLEVELAND</City>
          <State>OH</State>
          <ZIPCode>441935012</ZIPCode>
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        <EINOfRecipient>340714585</EINOfRecipient>
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        <AmountOfCashGrant>7089</AmountOfCashGrant>
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        <MethodOfValuation>N/A</MethodOfValuation>
        <DescriptionOfNonCashAssistance>N/A</DescriptionOfNonCashAssistance>
        <PurposeOfGrant>CLINICAL RESEARCH</PurposeOfGrant>
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      <RecipientTable>
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          <BusinessNameLine1>CLINICAL ALLIANCE FOR RESEARCH AND EDUCATION</BusinessNameLine1>
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          <AddressLine1>3289 WOODBURN ROAD SUITE 250</AddressLine1>
          <City>ANNANDALE</City>
          <State>VA</State>
          <ZIPCode>22003</ZIPCode>
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        <AmountOfNonCashAssistance>0</AmountOfNonCashAssistance>
        <MethodOfValuation>N/A</MethodOfValuation>
        <DescriptionOfNonCashAssistance>N/A</DescriptionOfNonCashAssistance>
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          <BusinessNameLine1>COMSYS INFO TECHNOLOGY SERVICES LLC</BusinessNameLine1>
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          <AddressLine1>DBA EXPERIS IT SERVICES US LLC P O</AddressLine1>
          <AddressLine2>BOX 905378</AddressLine2>
          <City>CHARLOTTE</City>
          <State>NC</State>
          <ZIPCode>282905378</ZIPCode>
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        <EINOfRecipient>751300240</EINOfRecipient>
        <AmountOfCashGrant>260390</AmountOfCashGrant>
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        <MethodOfValuation>N/A</MethodOfValuation>
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        <RecipientNameBusiness>
          <BusinessNameLine1>CONCEPT SYSTEMS INCORPORATED</BusinessNameLine1>
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          <AddressLine1>136 EAST STATE ST</AddressLine1>
          <City>ITHACA</City>
          <State>NY</State>
          <ZIPCode>14850</ZIPCode>
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        <EINOfRecipient>161473796</EINOfRecipient>
        <AmountOfCashGrant>261302</AmountOfCashGrant>
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        <MethodOfValuation>N/A</MethodOfValuation>
        <DescriptionOfNonCashAssistance>N/A</DescriptionOfNonCashAssistance>
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          <BusinessNameLine1>DANA FARBER CANCER INSTITUTE</BusinessNameLine1>
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          <AddressLine1>RESEARCH ACCOUNTING MAIL STOP BP451</AddressLine1>
          <AddressLine2>450 BROOKLINE AVENUE</AddressLine2>
          <City>BOSTON</City>
          <State>MA</State>
          <ZIPCode>02215</ZIPCode>
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        <EINOfRecipient>042263040</EINOfRecipient>
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        <AmountOfCashGrant>82862</AmountOfCashGrant>
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        <DescriptionOfNonCashAssistance>N/A</DescriptionOfNonCashAssistance>
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          <BusinessNameLine1>DISTRICT OF COLUMBIA GOV DC TREASURY</BusinessNameLine1>
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          <AddressLine1>899 NORTH CAPITOL NE 4TH FLOOR</AddressLine1>
          <City>WASHINGTON</City>
          <State>DC</State>
          <ZIPCode>20002</ZIPCode>
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        <EINOfRecipient>536001131</EINOfRecipient>
        <IRCSection>GOVERNMENT</IRCSection>
        <AmountOfCashGrant>206151</AmountOfCashGrant>
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        <MethodOfValuation>N/A</MethodOfValuation>
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        <PurposeOfGrant>VACCINE AND INFECTIOUS DISEASE</PurposeOfGrant>
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      <RecipientTable>
        <RecipientNameBusiness>
          <BusinessNameLine1>DUKE UNIVERSITY</BusinessNameLine1>
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        <AddressUS>
          <AddressLine1>ACCOUNTS RECEIVABLE LOCKBOX P O BOX</AddressLine1>
          <AddressLine2>602651</AddressLine2>
          <City>CHARLOTTE</City>
          <State>NC</State>
          <ZIPCode>282602651</ZIPCode>
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        <EINOfRecipient>560532129</EINOfRecipient>
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        <AmountOfCashGrant>1949817</AmountOfCashGrant>
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          <BusinessNameLine1>EMORY UNIVERSITY</BusinessNameLine1>
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          <AddressLine1>P O BOX 935084</AddressLine1>
          <City>ATLANTA</City>
          <State>GA</State>
          <ZIPCode>311935084</ZIPCode>
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        <EINOfRecipient>580566256</EINOfRecipient>
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        <AmountOfCashGrant>1325759</AmountOfCashGrant>
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        <PurposeOfGrant>VACCINE AND INFECTIOUS DISEASE</PurposeOfGrant>
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          <BusinessNameLine1>EXAMINATION MANAGEMENT SERVICES INC</BusinessNameLine1>
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        <AddressUS>
          <AddressLine1>3050 REGENT BLVD SUITE 400</AddressLine1>
          <City>IRVING</City>
          <State>TX</State>
          <ZIPCode>75063</ZIPCode>
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        <MethodOfValuation>N/A</MethodOfValuation>
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        <PurposeOfGrant>PUBLIC HEALTH SCIENCES</PurposeOfGrant>
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          <BusinessNameLine1>FENWAY COMMUNITY HEALTH</BusinessNameLine1>
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          <AddressLine1>1340 BOYLSTON ST</AddressLine1>
          <City>BOSTON</City>
          <State>MA</State>
          <ZIPCode>02215</ZIPCode>
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        <EINOfRecipient>042510564</EINOfRecipient>
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          <BusinessNameLine1>FISHER BIOSERVICES</BusinessNameLine1>
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        <AddressUS>
          <AddressLine1>P O BOX 418395</AddressLine1>
          <City>BOSTON</City>
          <State>MA</State>
          <ZIPCode>022418395</ZIPCode>
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        <MethodOfValuation>N/A</MethodOfValuation>
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        <PurposeOfGrant>PUBLIC HEALTH SCIENCES</PurposeOfGrant>
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          <BusinessNameLine1>FRONTIER SCIENCE AND TECHNOLOGY</BusinessNameLine1>
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          <AddressLine1>P O BOX 983027</AddressLine1>
          <City>BOSTON</City>
          <State>MA</State>
          <ZIPCode>022983027</ZIPCode>
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        <RecipientNameBusiness>
          <BusinessNameLine1>GENERAL HOSPITAL CORPORATION</BusinessNameLine1>
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        <AddressUS>
          <AddressLine1>RESEARCH FINANCE BANK OF AMERICA NA</AddressLine1>
          <AddressLine2>P O BOX 3829</AddressLine2>
          <City>BOSTON</City>
          <State>MA</State>
          <ZIPCode>022413829</ZIPCode>
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      <RecipientTable>
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          <BusinessNameLine1>GENERAL HOSPITAL CORPORATION</BusinessNameLine1>
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        <AddressUS>
          <AddressLine1>RESEARCH FINANCE P O BOX 414876</AddressLine1>
          <City>BOSTON</City>
          <State>MA</State>
          <ZIPCode>022414876</ZIPCode>
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          <BusinessNameLine1>GROUP HEALTH COOPERATIVE</BusinessNameLine1>
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        <AddressUS>
          <AddressLine1>ATTN CASH DESK P O BOX 34587</AddressLine1>
          <City>SEATTLE</City>
          <State>WA</State>
          <ZIPCode>981249990</ZIPCode>
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          <BusinessNameLine1>H LEE MOFFITT CANCER CENTER &amp; RESEARCH INSTITUTE</BusinessNameLine1>
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          <AddressLine1>MRC-RESADM 12902 MAGNOLIA DRIVE</AddressLine1>
          <City>TAMPA</City>
          <State>FL</State>
          <ZIPCode>33612</ZIPCode>
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        <RecipientNameBusiness>
          <BusinessNameLine1>H LEE MOFFITT CANCER CENTER &amp; RESEARCH INSTITUTE</BusinessNameLine1>
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          <AddressLine1>MRC-RESADM 12902 MAGNOLIA DRIVE</AddressLine1>
          <City>TAMPA</City>
          <State>FL</State>
          <ZIPCode>33612</ZIPCode>
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          <BusinessNameLine1>HEKTOEN INSTITUTE FOR MED RESEARCH LLC</BusinessNameLine1>
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          <AddressLine1>2240 W OGDEN AVE</AddressLine1>
          <City>CHICAGO</City>
          <State>IL</State>
          <ZIPCode>606129982</ZIPCode>
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          <BusinessNameLine1>ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI</BusinessNameLine1>
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          <AddressLine1>DIRECTOR SPONSORED PROJ ACCTNG ONE</AddressLine1>
          <AddressLine2>GUSTAVE L LEVY PLACE BOX 3500</AddressLine2>
          <City>NEW YORK</City>
          <State>NY</State>
          <ZIPCode>10029</ZIPCode>
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          <BusinessNameLine1>ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI</BusinessNameLine1>
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          <AddressLine1>ONE GUSTAVE L LEVY PLACE BOX 1410</AddressLine1>
          <City>NEW YORK</City>
          <State>NY</State>
          <ZIPCode>100296574</ZIPCode>
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          <BusinessNameLine1>INFECTIOUS DISEASE CNSLTNTS MD PA</BusinessNameLine1>
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        <AddressUS>
          <AddressLine1>1701 N MILLS AVE</AddressLine1>
          <City>ORLANDO</City>
          <State>FL</State>
          <ZIPCode>32803</ZIPCode>
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          <BusinessNameLine1>J CRAIG VENTER INSTITUTE</BusinessNameLine1>
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        <AddressUS>
          <AddressLine1>9704 MEDICAL CENTER DRIVE</AddressLine1>
          <City>ROCKVILLE</City>
          <State>MD</State>
          <ZIPCode>20850</ZIPCode>
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        <EINOfRecipient>521842938</EINOfRecipient>
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        <AmountOfCashGrant>38117</AmountOfCashGrant>
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        <PurposeOfGrant>VACCINE AND INFECTIOUS DISEASE</PurposeOfGrant>
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      <RecipientTable>
        <RecipientNameBusiness>
          <BusinessNameLine1>JOHNS HOPKINS UNIVERSITY</BusinessNameLine1>
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        <AddressUS>
          <AddressLine1>C/O BANK OF AMERICA 12529 COLLECTIO</AddressLine1>
          <AddressLine2>S CENTER DRIVE</AddressLine2>
          <City>CHICAGO</City>
          <State>IL</State>
          <ZIPCode>60693</ZIPCode>
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        <EINOfRecipient>520595110</EINOfRecipient>
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        <DescriptionOfNonCashAssistance>N/A</DescriptionOfNonCashAssistance>
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      <RecipientTable>
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          <BusinessNameLine1>JOHNS HOPKINS UNIVERSITY</BusinessNameLine1>
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        <AddressUS>
          <AddressLine1>C/O BANK OF AMERICA 12529 COLLECTIO</AddressLine1>
          <AddressLine2>S CENTER DRIVE</AddressLine2>
          <City>CHICAGO</City>
          <State>IL</State>
          <ZIPCode>60693</ZIPCode>
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        <AmountOfCashGrant>128531</AmountOfCashGrant>
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        <MethodOfValuation>N/A</MethodOfValuation>
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          <BusinessNameLine1>JOHNS HOPKINS UNIVERSITY</BusinessNameLine1>
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          <AddressLine1>C/O BANK OF AMERICA 12529 COLLECTIO</AddressLine1>
          <AddressLine2>S CENTER DRIVE</AddressLine2>
          <City>CHICAGO</City>
          <State>IL</State>
          <ZIPCode>60693</ZIPCode>
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          <BusinessNameLine1>KAISER FOUNDATION HOSPITALS</BusinessNameLine1>
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          <AddressLine1>KAISER FOUNDATION RESEARCH</AddressLine1>
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          <State>CA</State>
          <ZIPCode>946123433</ZIPCode>
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          <BusinessNameLine1>LABKEY CORPORATION</BusinessNameLine1>
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          <AddressLine1>2226 EASTLAKE AVE E 101</AddressLine1>
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          <State>WA</State>
          <ZIPCode>98102</ZIPCode>
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          <BusinessNameLine1>LIFE TECHNOLOGIES CORPORATION</BusinessNameLine1>
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          <AddressLine1>APPLIED BIOSYSTEMS 32000 COLLECTION</AddressLine1>
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          <ZIPCode>606930320</ZIPCode>
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          <BusinessNameLine1>LOUISIANA STATE UNIVERSITY HEALTH</BusinessNameLine1>
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          <AddressLine1>433 BOLIVAR ST</AddressLine1>
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          <BusinessNameLine1>MASSACHUSETTS INSTITUTE OF TECHNOLOGY</BusinessNameLine1>
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          <AddressLine1>SLOAN MANAGEMENT REVIEW P O BOX</AddressLine1>
          <AddressLine2>55254</AddressLine2>
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          <ZIPCode>80322</ZIPCode>
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          <BusinessNameLine1>MAYO CLINIC ARIZONA</BusinessNameLine1>
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          <AddressLine1>MAYO CLINIC ARIZONA GRANTS REMIT</AddressLine1>
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          <ZIPCode>559034008</ZIPCode>
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          <BusinessNameLine1>MAYO CLINIC ROCHESTER</BusinessNameLine1>
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          <AddressLine1>200 FIRST STREET SW</AddressLine1>
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          <BusinessNameLine1>MEDICAL COLLEGE OF WISCONSIN</BusinessNameLine1>
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          <AddressLine1>DEPT OF PEDIATRICS M3018 8701</AddressLine1>
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          <ZIPCode>53226</ZIPCode>
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          <BusinessNameLine1>MIRIAM HOSPITAL</BusinessNameLine1>
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          <AddressLine1>ADMIN-ALDRICH 3 593 EDDY STREET</AddressLine1>
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          <State>RI</State>
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          <BusinessNameLine1>NATIONAL JEWISH HEALTH</BusinessNameLine1>
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          <AddressLine1>1400 JACKSON STREET ROOM M216</AddressLine1>
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          <BusinessNameLine1>NATIONAL MARROW DONOR PROGRAM</BusinessNameLine1>
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          <AddressLine1>NW 8428 P O BOX 1450</AddressLine1>
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          <BusinessNameLine1>NAVAL MEDICAL RESEARCH CENTER</BusinessNameLine1>
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          <AddressLine1>503 ROBERT GRANT AVE</AddressLine1>
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          <AddressLine1>1200 PROSPECT AVENUE</AddressLine1>
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          <ZIPCode>11590</ZIPCode>
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          <BusinessNameLine1>NEW YORK UNIVERSITY SCHOOL OF MEDICINE</BusinessNameLine1>
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          <AddressLine1>360 HUNTINGTON AVE</AddressLine1>
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          <BusinessNameLine1>NORTHWEST COMMUNITIES EDUCATION CENTER</BusinessNameLine1>
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          <BusinessNameLine1>NORTHWEST PORTLAND AREA INDIAN HEALTH BOARD</BusinessNameLine1>
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          <AddressLine1>2121 SW BROADWAY STE 300</AddressLine1>
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          <ZIPCode>97201</ZIPCode>
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          <BusinessNameLine1>NY CITY DEPT OF HLTH AND MENTAL HYGIENE</BusinessNameLine1>
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          <AddressLine2>48 15TH FLOOR</AddressLine2>
          <City>QUEENS</City>
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          <AddressLine2>0690 SW BANCROFT STREET</AddressLine2>
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          <State>OR</State>
          <ZIPCode>97239</ZIPCode>
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          <City>PORTLAND</City>
          <State>OR</State>
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          <BusinessNameLine1>OWL BIOMEDICAL INC</BusinessNameLine1>
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          <AddressLine1>75 ROBIN HILL RD</AddressLine1>
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          <State>CA</State>
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          <State>MA</State>
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          <AddressLine1>MSKCC FINANCE GENERAL POST OFFICE P</AddressLine1>
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          <BusinessNameLine1>TEXAS A AND M RESEARCH FOUNDATION</BusinessNameLine1>
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          <AddressLine1>C/O WELLS FARGO BANK P O BOX 201918</AddressLine1>
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          <AddressLine1>11 ROPE FERRY ROAD 6210</AddressLine1>
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          <State>NH</State>
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          <State>HI</State>
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          <BusinessNameLine1>UNIVERSITY OF IDAHO</BusinessNameLine1>
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          <AddressLine1>MSC09 5225 1 UNIVERSITY OF NEW</AddressLine1>
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          <AddressLine1>OFFICE OF SPONSORED RESEARCH 104</AddressLine1>
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          <City>CHAPEL HILL</City>
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          <BusinessNameLine1>UNIVERSITY OF NORTH CAROLINA</BusinessNameLine1>
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          <BusinessNameLine1>UNIVERSITY OF PITTSBURGH</BusinessNameLine1>
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          <AddressLine1>P O BOX 371220</AddressLine1>
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          <BusinessNameLine1>UNIVERSITY OF PITTSBURGH</BusinessNameLine1>
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          <AddressLine1>910 GENESEE STREET SUITE 200</AddressLine1>
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          <AddressLine1>910 GENESEE STREET SUITE 200</AddressLine1>
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          <BusinessNameLine1>UNIVERSITY OF SOUTHERN CALIFORNIA</BusinessNameLine1>
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          <AddressLine1>3500S FIGUEROA ST SUITE 102</AddressLine1>
          <City>LOS ANGELES</City>
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          <ZIPCode>900898001</ZIPCode>
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          <BusinessNameLine1>UNIVERSITY OF SOUTHERN CALIFORNIA</BusinessNameLine1>
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          <AddressLine1>SPONSORED PROJECTS ACCOUNTING FILE</AddressLine1>
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          <BusinessNameLine1>UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL</BusinessNameLine1>
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          <AddressLine1>OFFICE OF POST AWARD ADMINISTRATION</AddressLine1>
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          <State>TX</State>
          <ZIPCode>752841765</ZIPCode>
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          <BusinessNameLine1>UNIVERSITY OF UTAH</BusinessNameLine1>
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          <AddressLine1>201 S PRESIDENTS CIRCLE RM 406</AddressLine1>
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          <State>UT</State>
          <ZIPCode>841129020</ZIPCode>
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          <BusinessNameLine1>UNIVERSITY OF VERMONT</BusinessNameLine1>
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          <AddressLine1>217 WATERMAN BUILDING 85 SOUTH</AddressLine1>
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          <City>BURLINGTON</City>
          <State>VT</State>
          <ZIPCode>054050160</ZIPCode>
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          <AddressLine1>4333 BROOKLYN AVE NE BOX 359472</AddressLine1>
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          <ZIPCode>981959472</ZIPCode>
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          <BusinessNameLine1>UNIVERSITY OF WASHINGTON</BusinessNameLine1>
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          <BusinessNameLine1>UNIVERSITY OF WISCONSIN</BusinessNameLine1>
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          <AddressLine1>OFFICE FOR RESEARCH SPONSORED</AddressLine1>
          <AddressLine2>PROGRAMS DRAWER 538</AddressLine2>
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          <State>WI</State>
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          <BusinessNameLine1>VACCINE &amp; GENE THERAPY INSTITUTE FLORIDA</BusinessNameLine1>
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          <City>PULLMAN</City>
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          <AddressLine1>CAMPUS BOX 1034</AddressLine1>
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          <BusinessNameLine1>WASHINGTON UNIVERSITY DBA</BusinessNameLine1>
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          <State>MO</State>
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        <EINOfRecipient>430653611</EINOfRecipient>
        <IRCSection>501(C)(3)</IRCSection>
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        <MethodOfValuation>N/A</MethodOfValuation>
        <DescriptionOfNonCashAssistance>N/A</DescriptionOfNonCashAssistance>
        <PurposeOfGrant>HUMAN BIOLOGY</PurposeOfGrant>
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      <RecipientTable>
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          <BusinessNameLine1>YAKIMA VALLEY FARM WORKERS CLINIC</BusinessNameLine1>
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          <AddressLine1>CENTRAL ADMINISTRATION 518 W FIRST</AddressLine1>
          <AddressLine2>AVE PO BOX 190</AddressLine2>
          <City>TOPPENISH</City>
          <State>WA</State>
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        <MethodOfValuation>N/A</MethodOfValuation>
        <DescriptionOfNonCashAssistance>N/A</DescriptionOfNonCashAssistance>
        <PurposeOfGrant>PUBLIC HEALTH SCIENCES</PurposeOfGrant>
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      <RecipientTable>
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          <BusinessNameLine1>YALE UNIVERSITY</BusinessNameLine1>
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        <AmountOfNonCashAssistance>937698</AmountOfNonCashAssistance>
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        <NamePerson>DENISE GALLOWAY PHD</NamePerson>
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        <NamePerson>STEVEN G SELF PHD</NamePerson>
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        <NamePerson>MARTIN A CHEEVER MD</NamePerson>
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        <NamePerson>BRIAN J REID MD PHD</NamePerson>
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        <NamePerson>IRWIN D BERNSTEIN MD</NamePerson>
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        <NamePerson>F MARC STEWART MD</NamePerson>
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        <NamePerson>JAMES KUBLIN PHD</NamePerson>
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        <ReturnReference>PART I, LINE 1A</ReturnReference>
        <Explanation>FIRST CLASS AIR TRAVEL IS ALLOWED CONSISTENT WITH FEDERAL REIMBURSEMENT REGULATIONS AND GENERALLY ONLY WHEN COACH FARE IS NOT AVAILABLE. AIRFARE AND NORMAL TRAVEL EXPENSES ARE PAID FOR THE PRESIDENT AND DIRECTOR'S SPOUSE FOR TRIPS INVOLVING FUNDRAISING FOR THE CENTER. SOCIAL CLUB DUES ARE PAID FOR THE CENTER'S PRESIDENT &amp; DIRECTOR AND VICE PRESIDENT OF DEVELOPMENT. NONE OF THESE ITEMS ARE CONSIDERED TAXABLE COMPENSATION TO THESE INDIVIDUALS.</Explanation>
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        <ReturnReference>PART I, LINE 7</ReturnReference>
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      <Form990ScheduleKPartII>
        <BondReferenceCd>A</BondReferenceCd>
        <TotalProceeds>353903</TotalProceeds>
        <IssuanceCostsFromProceeds>1252</IssuanceCostsFromProceeds>
        <OtherSpentProceeds>352651</OtherSpentProceeds>
        <YearOfSubstCompletion>2012</YearOfSubstCompletion>
        <CurrentRefunding>1</CurrentRefunding>
        <AdvanceRefunding>0</AdvanceRefunding>
        <FinalAllocationMade>1</FinalAllocationMade>
        <AdequateBooksAndRecdsMaintaind>1</AdequateBooksAndRecdsMaintaind>
      </Form990ScheduleKPartII>
      <Form990ScheduleKPartII>
        <BondReferenceCd>B</BondReferenceCd>
        <TotalProceeds>84446097</TotalProceeds>
        <IssuanceCostsFromProceeds>298748</IssuanceCostsFromProceeds>
        <CapitalExpenditures>12236162</CapitalExpenditures>
        <OtherSpentProceeds>69478726</OtherSpentProceeds>
        <AmountUnspent>2432461</AmountUnspent>
        <CurrentRefunding>1</CurrentRefunding>
        <AdvanceRefunding>0</AdvanceRefunding>
        <FinalAllocationMade>1</FinalAllocationMade>
        <AdequateBooksAndRecdsMaintaind>1</AdequateBooksAndRecdsMaintaind>
      </Form990ScheduleKPartII>
      <Form990ScheduleKPartIII>
        <BondReferenceCd>A</BondReferenceCd>
        <OwningBondFinancedProperty>0</OwningBondFinancedProperty>
        <AnyLeaseArrangements>0</AnyLeaseArrangements>
        <MngmentCntrctBondFinancdPrprty>0</MngmentCntrctBondFinancdPrprty>
        <AnyResearchAgreements>0</AnyResearchAgreements>
        <PrcntgePrvtBusinessUseByOthers>0.00000</PrcntgePrvtBusinessUseByOthers>
        <PercentageOfPrvtBusinessReUBI>0.00000</PercentageOfPrvtBusinessReUBI>
        <TotalPrivateBusinessUse>0.00000</TotalPrivateBusinessUse>
        <BondIssMeetPrvtSecurityPayTest>0</BondIssMeetPrvtSecurityPayTest>
        <ChangeInUseBondFinancedProp>0</ChangeInUseBondFinancedProp>
        <NonQualifiedBondRemedProcdrs>1</NonQualifiedBondRemedProcdrs>
      </Form990ScheduleKPartIII>
      <Form990ScheduleKPartIII>
        <BondReferenceCd>B</BondReferenceCd>
        <OwningBondFinancedProperty>0</OwningBondFinancedProperty>
        <AnyLeaseArrangements>0</AnyLeaseArrangements>
        <MngmentCntrctBondFinancdPrprty>1</MngmentCntrctBondFinancdPrprty>
        <EngageBondCounselContracts>1</EngageBondCounselContracts>
        <AnyResearchAgreements>1</AnyResearchAgreements>
        <EngageBondCounselResearch>1</EngageBondCounselResearch>
        <PrcntgePrvtBusinessUseByOthers>0.01500</PrcntgePrvtBusinessUseByOthers>
        <PercentageOfPrvtBusinessReUBI>0.00200</PercentageOfPrvtBusinessReUBI>
        <TotalPrivateBusinessUse>0.01700</TotalPrivateBusinessUse>
        <BondIssMeetPrvtSecurityPayTest>0</BondIssMeetPrvtSecurityPayTest>
        <ChangeInUseBondFinancedProp>0</ChangeInUseBondFinancedProp>
        <NonQualifiedBondRemedProcdrs>1</NonQualifiedBondRemedProcdrs>
      </Form990ScheduleKPartIII>
      <Form990ScheduleKPartIV>
        <BondReferenceCd>A</BondReferenceCd>
        <Form8038TFiled>0</Form8038TFiled>
        <RebateNotDueYet>1</RebateNotDueYet>
        <ExceptionToRebate>0</ExceptionToRebate>
        <NoRebateDue>0</NoRebateDue>
        <VariableRateIssue>1</VariableRateIssue>
        <HedgeIdentifiedInBooksAndRecds>0</HedgeIdentifiedInBooksAndRecds>
        <GrossProceedsInvestedInGIC>0</GrossProceedsInvestedInGIC>
        <GrossProceedsInvested>0</GrossProceedsInvested>
        <WrittenProcToMonitorReqs>1</WrittenProcToMonitorReqs>
      </Form990ScheduleKPartIV>
      <Form990ScheduleKPartIV>
        <BondReferenceCd>B</BondReferenceCd>
        <Form8038TFiled>0</Form8038TFiled>
        <RebateNotDueYet>1</RebateNotDueYet>
        <ExceptionToRebate>0</ExceptionToRebate>
        <NoRebateDue>0</NoRebateDue>
        <VariableRateIssue>1</VariableRateIssue>
        <HedgeIdentifiedInBooksAndRecds>0</HedgeIdentifiedInBooksAndRecds>
        <GrossProceedsInvestedInGIC>0</GrossProceedsInvestedInGIC>
        <GrossProceedsInvested>0</GrossProceedsInvested>
        <WrittenProcToMonitorReqs>1</WrittenProcToMonitorReqs>
      </Form990ScheduleKPartIV>
      <Form990ScheduleKPartV>
        <BondReferenceCd>A</BondReferenceCd>
        <ProcToUndertkCorrectiveAction>1</ProcToUndertkCorrectiveAction>
      </Form990ScheduleKPartV>
      <Form990ScheduleKPartV>
        <BondReferenceCd>B</BondReferenceCd>
        <ProcToUndertkCorrectiveAction>1</ProcToUndertkCorrectiveAction>
      </Form990ScheduleKPartV>
    </IRS990ScheduleK>
    <IRS990ScheduleL documentId="RetDoc1042800001">
      <Form990ScheduleLPartIV>
        <NameOfInterestedPerson>
          <NameBusiness>
            <BusinessNameLine1>IKARIA INC</BusinessNameLine1>
          </NameBusiness>
        </NameOfInterestedPerson>
        <Relationship>SEE PART IV</Relationship>
        <AmountOfTransaction>2401154</AmountOfTransaction>
        <DescriptionOfTransaction>SEE PART IV</DescriptionOfTransaction>
        <SharingOfRevenues>0</SharingOfRevenues>
      </Form990ScheduleLPartIV>
      <Form990ScheduleLPartV>
        <Identifier>SCH L, PART IV, BUSINESS TRANSACTIONS INVOLVING INTERESTED PERSONS:</Identifier>
        <Explanation>(A) NAME OF PERSON: IKARIA, INC.(B) RELATIONSHIP BETWEEN INTERESTED PERSON AND ORGANIZATION:ROBERT NELSEN, ORGANIZATION TRUSTEE, IS A DIRECTOR OF IKARIA, INC.(C) AMOUNT OF TRANSACTION $ 2,401,154.(D) DESCRIPTION OF TRANSACTION: DIVIDEND INCOME AND RETURN OF INVESTMENT RECEIVED FROM INTERESTED PERSON(E) SHARING OF ORGANIZATION REVENUES? = NO</Explanation>
      </Form990ScheduleLPartV>
    </IRS990ScheduleL>
    <IRS990ScheduleM documentId="RetDoc1042900001">
      <SecuritiesPubliclyTraded>
        <NonCashCheckbox>X</NonCashCheckbox>
        <NumberOfContributions>50</NumberOfContributions>
        <NoncashContribsRptdF990>1829833</NoncashContribsRptdF990>
        <MethodOfDeterminingRevenues>MARKET VALUE</MethodOfDeterminingRevenues>
      </SecuritiesPubliclyTraded>
      <OtherNonCashContributionsTable>
        <NonCashCheckbox>X</NonCashCheckbox>
        <Description>EQUIPMENT</Description>
        <NumberOfContributions>1</NumberOfContributions>
        <NoncashContribsRptdF990>1007589</NoncashContribsRptdF990>
        <MethodOfDeterminingRevenues>MARKET VALUE</MethodOfDeterminingRevenues>
      </OtherNonCashContributionsTable>
      <OtherNonCashContributionsTable>
        <NonCashCheckbox>X</NonCashCheckbox>
        <Description>BEDDING</Description>
        <NumberOfContributions>4</NumberOfContributions>
        <NoncashContribsRptdF990>25740</NoncashContribsRptdF990>
        <MethodOfDeterminingRevenues>MARKET VALUE</MethodOfDeterminingRevenues>
      </OtherNonCashContributionsTable>
      <OtherNonCashContributionsTable>
        <NonCashCheckbox>X</NonCashCheckbox>
        <Description>AUCTION ITEMS</Description>
        <NumberOfContributions>350</NumberOfContributions>
        <NoncashContribsRptdF990>533405</NoncashContribsRptdF990>
        <MethodOfDeterminingRevenues>MARKET VALUE</MethodOfDeterminingRevenues>
      </OtherNonCashContributionsTable>
      <NumberOf8283Received>0</NumberOf8283Received>
      <AnyPropertyThatMustBeHeld>0</AnyPropertyThatMustBeHeld>
      <ReviewProcessUnusualNCGifts>1</ReviewProcessUnusualNCGifts>
      <ThirdPartiesUsed>0</ThirdPartiesUsed>
      <Form990ScheduleMPartII>
        <Identifier>METHOD FOR DETERMINING NUMBER OF CONTRIBUTIONS:</Identifier>
        <ReturnReference>PART I, COLUMN (B):</ReturnReference>
        <Explanation>THE NUMBER IN PART I, COLUMN (B) REPRESENTS THE NUMBER OF CONTRIBUTIONS RECEIVED.</Explanation>
      </Form990ScheduleMPartII>
    </IRS990ScheduleM>
    <IRS990ScheduleO documentId="RetDoc1044400001">
      <GeneralExplanation>
        <ReturnReference>FORM 990, PART VI, SECTION A, LINE 2</ReturnReference>
        <Explanation>MARK GROUDINE, RICH MCCUNE, MYRA TANITA, AND FRED APPELBAUM HAVE BUSINESS RELATIONSHIPS. EACH NAMED INDIVIDUAL SERVES AS FRED HUTCH BOARD MEMBERS OR OFFICERS, AND THESE INDIVIDUALS ARE ALSO CURRENT BOARD MEMBERS OR OFFICERS OF ANOTHER ORGANIZATION.</Explanation>
      </GeneralExplanation>
      <GeneralExplanation>
        <ReturnReference>FORM 990, PART VI, SECTION B, LINE 11</ReturnReference>
        <Explanation>UNDER THE CENTER'S BYLAWS, THE FINANCE COMMITTEE IS RESPONSIBLE FOR REVIEWING AND INVESTIGATING FINANCIAL TRANSACTIONS OF FHCRC INCLUDING RESPONSIBILITY OF INTERNAL AND EXTERNAL AUDITING AND FOR MAKING RECOMMENDATIONS TO THE BOARD CONCERNING THESE MATTERS. FHCRC'S VICE PRESIDENT OF FINANCE &amp; CHIEF FINANCIAL OFFICER AND HIS STAFF WORK CLOSELY WITH THE OUTSIDE ACCOUNTING FIRM FHCRC ENGAGES TO PREPARE THE FORM 990. THE DRAFT FORM 990 IS ALSO REVIEWED BY THE CORPORATE TREASURER, THE EXECUTIVE VICE PRESIDENT &amp; CHIEF OPERATING OFFICER AND THE VICE PRESIDENT &amp; GENERAL COUNSEL PRIOR TO PROVIDING IT TO THE FINANCE COMMITTEE. THE FINANCE COMMITTEE CONSULTS WITH THE CHIEF OPERATING OFFICER, CHIEF FINANCIAL OFFICER, GENERAL COUNSEL AND CORPORATE TREASURER AND SUCH OTHER PERSONS THE FINANCE COMMITTEE MAY DESIGNATE TO REVIEW THE DRAFT FORM 990. SUBSEQUENT TO ITS REVIEW, THE FINANCE COMMITTEE REPORTS TO THE BOARD REGARDING ITS OVERSIGHT OF FORM 990. THE FINAL DRAFT IS PROVIDED TO THE FULL BOARD PRIOR TO FILING THE RETURN.</Explanation>
      </GeneralExplanation>
      <GeneralExplanation>
        <ReturnReference>FORM 990, PART VI, SECTION B, LINE 12C</ReturnReference>
        <Explanation>THE EXECUTIVE COMMITTEE OF THE BOARD IS RESPONSIBLE FOR MONITORING CONFLICTS OF INTEREST INVOLVING TRUSTEES OR THE PRESIDENT &amp; DIRECTOR OF THE CENTER. THE PRESIDENT &amp; DIRECTOR OF THE CENTER IS RESPONSIBLE FOR MONITORING CONFLICTS OF INTEREST INVOLVING OTHER OFFICERS, SCIENTIFIC STAFF AND OTHER KEY PERSONNEL DESIGNATED BY THE PRESIDENT &amp; DIRECTOR. UNDER THE FHCRC CONFLICT OF INTEREST POLICY AND RELATED GUIDELINES, AN ANNUAL CONFLICT OF INTEREST DISCLOSURE DOCUMENT AIMED AT DETERMINING FAMILY AND BUSINESS RELATIONSHIPS AND TRANSACTIONS THAT CONSTITUTE A CONFLICT OF INTEREST UNDER THE POLICY, IS DISTRIBUTED TO AND MUST BE COMPLETED BY ALL COVERED PERSONS. DISCLOSURES BY TRUSTEES AND THE PRESIDENT &amp; DIRECTOR ARE REVIEWED BY THE OFFICE OF THE GENERAL COUNSEL WHO REPORTS ANY CONFLICTS TO THE EXECUTIVE COMMITTEE WITH RECOMMENDATIONS ON APPROPRIATE TERMS FOR A CONFLICT MANAGEMENT PLAN. CONFLICT MANAGEMENT PLANS FOR TRUSTEES AND THE PRESIDENT &amp; DIRECTOR ARE REVIEWED AND APPROVED BY THE EXECUTIVE COMMITTEE AND SIGNED BY THE PERSON WITH THE CONFLICT OF INTEREST AND THE CHAIR OF THE BOARD. DISCLOSURE BY MEMBERS OF THE SCIENTIFIC STAFF, OFFICERS OTHER THAN THE PRESIDENT &amp; DIRECTOR AND OTHER KEY PERSONNEL DESIGNATED BY THE PRESIDENT &amp; DIRECTOR ARE REVIEWED BY THE OFFICE OF THE PRESIDENT &amp; DIRECTOR, THE OFFICE OF THE GENERAL COUNSEL, AND THE DIRECTOR OF THE DIVISION IN WHICH THE PERSON HAS HIS OR HER PRIMARY APPOINTMENT OR RESPONSIBILITIES. IF A CONFLICT IS DETERMINED TO EXIST UNDER THE POLICY A WRITTEN CONFLICT MANAGEMENT PLAN IS RECOMMENDED BY THE OFFICE OF THE GENERAL COUNSEL AND APPROVED AND SIGNED BY THE OFFICE OF THE DIRECTOR, THE OFFICE OF THE GENERAL COUNSEL AND THE DIVISION DIRECTOR AS WELL AS THE PERSON WHO HAS THE CONFLICT. CONFLICT MANAGEMENT PLANS ARE DESIGNATED TO MANAGE, REDUCE AND ELIMINATE CONFLICTS TO PREVENT BIAS, IMPROPER INFLUENCE, OR MISUSE OF FHCRC OR GOVERNMENT RESOURCES. THE CONFLICT MANAGEMENT PLANS FOR TRUSTEES USUALLY REQUIRE THE AFFECTED TRUSTEE TO RECUSE HIMSELF OR HERSELF FROM VOTING ON ANY MATTERS INVOLVING THE AFFECTED TRANSACTION OR RELATIONSHIP ALTHOUGH HE OR SHE IS ALLOWED TO PROVIDE FACTUAL INFORMATION IF REQUESTED BY THE BOARD OF THE EXECUTIVE COMMITTEE. ALL TRANSACTIONS REQUIRING BOARD OR COMMITTEE APPROVAL MUST BE APPROVED BY A MAJORITY OF DISINTERESTED PERSONS. CONFLICT MANAGEMENT PLANS INVOLVING SCIENTIFIC STAFF, OFFICER OR OTHER KEY PERSONNEL USUALLY IMPOSE ONE OR MORE OF THE FOLLOWING CONDITIONS OR RESTRICTIONS: 1) PUBLIC DISCLOSURE OF THE INTEREST, 2) MONITORING OF RESEARCH BY INDEPENDENT REVIEWERS, 3) MODIFICATION OF THE RESEARCH PLAN, 4) DISQUALIFICATION FROM PARTICIPATION IN ALL OF OR A PORTION OF THE RESEARCH BY THE PERSON WITH THE CONFLICT OF INTEREST, 5) DIVESTURE OF THE INTEREST, 6) SEVERANCE OF THE RELATIONSHIP CREATING THE CONFLICT OF INTEREST.</Explanation>
      </GeneralExplanation>
      <GeneralExplanation>
        <ReturnReference>FORM 990, PART VI, SECTION B, LINE 15</ReturnReference>
        <Explanation>COMPENSATION FOR THE PRESIDENT &amp; DIRECTOR IS DETERMINED AND APPROVED BY THE BOARD COMPENSATION COMMITTEE. THE COMPENSATION OF OTHER OFFICERS AND KEY PERSONNEL AT FHCRC IS DETERMINED BY THE PRESIDENT &amp; DIRECTOR SUBJECT TO RATIFICATION BY THE COMPENSATION COMMITTEE. THE COMPENSATION COMMITTEE HAS DEVELOPED, CONSISTENT WITH THE ORGANIZATION'S PHILOSOPHY AND PRINCIPLES, GUIDELINES FOR DETERMINING COMPENSATION AND BENEFITS. THE COMPENSATION COMMITTEE ALSO HIRES A QUALIFIED INDEPENDENT COMPENSATION SPECIALIST ("INDEPENDENT EXPERT") EVERY TWO YEARS TO REVIEW, ANALYZE AND PROVIDE BENCHMARKING DATA FOR THE TOTAL COMPENSATION PACKAGES OF ALL OFFICERS AND KEY EMPLOYEES. APPROPRIATE COMPARABILITY DATA IS OBTAINED FROM THE INDEPENDENT EXPERT. NO PERSON WITH A CONFLICT OF INTEREST MAY PARTICIPATE IN DETERMINING OR APPROVING ANY EXECUTIVE COMPENSATION. MEETINGS OF THE COMPENSATION COMMITTEE ARE DOCUMENTED IN MINUTES WHICH ARE APPROVED AT THE NEXT COMMITTEE MEETING. THE ABOVE PROCESS WAS LAST UNDERTAKEN IN 2012.</Explanation>
      </GeneralExplanation>
      <GeneralExplanation>
        <ReturnReference>FORM 990, PART VI, SECTION C, LINE 19</ReturnReference>
        <Explanation>WHILE FEDERAL TAX LAWS DO NOT MANDATE THAT THE ORGANIZATION'S GOVERNING DOCUMENTS, CONFLICT OF INTEREST POLICY AND FINANCIAL STATEMENTS BE MADE AVAILABLE FOR PUBLIC INSPECTION, THE ORGANIZATION MAKES THESE DOCUMENTS AVAILABLE UPON REQUEST.</Explanation>
      </GeneralExplanation>
      <GeneralExplanation>
        <Identifier>CHANGES IN NET ASSETS OR FUND BALANCES:</Identifier>
        <ReturnReference>FORM 990, PART XI, LINE 9:</ReturnReference>
        <Explanation>ADJUSTMENT FOR DECONSOLIDATION OF CONTROLLED AFFLIATE (SVRF) -1,820. SHARE OF LOSS FROM INVESTMENT IN SCCA RELATED TO PROCURE SEATTLE HOLDINGS -5,263,981.</Explanation>
      </GeneralExplanation>
    </IRS990ScheduleO>
    <IRS990ScheduleR documentId="RetDoc1043400001">
      <Form990ScheduleRPartI>
        <NameOfDisregardedEntity>
          <BusinessNameLine1>FH INTERNATIONAL LLC</BusinessNameLine1>
        </NameOfDisregardedEntity>
        <AddressUS>
          <AddressLine1>1100 FAIRVIEW AVENUE NORTH</AddressLine1>
          <City>SEATTLE</City>
          <State>WA</State>
          <ZIPCode>981091024</ZIPCode>
        </AddressUS>
        <EIN>462936650</EIN>
        <PrimaryActivities>JOINT VENTURE INVESTMENT</PrimaryActivities>
        <LegalDomicileState>WA</LegalDomicileState>
        <TotalIncome>0</TotalIncome>
        <EOYAssets>120000</EOYAssets>
        <DirectControllingEntityName>
          <BusinessNameLine1>FRED HUTCHINSON CANCER RESEARCH CENTER</BusinessNameLine1>
        </DirectControllingEntityName>
      </Form990ScheduleRPartI>
      <Form990ScheduleRPartII>
        <NameOfDisregardedEntity>
          <BusinessNameLine1>SEATTLE VACCINE RESEARCH FUND</BusinessNameLine1>
        </NameOfDisregardedEntity>
        <AddressUS>
          <AddressLine1>1100 FAIRVIEW AVENUE NORTH</AddressLine1>
          <City>SEATTLE</City>
          <State>WA</State>
          <ZIPCode>98109</ZIPCode>
        </AddressUS>
        <EIN>331111221</EIN>
        <PrimaryActivities>ANTIRETROVIRAL THERAPY FOR ELIGIBLE PARTICIPANTS</PrimaryActivities>
        <LegalDomicileState>WA</LegalDomicileState>
        <ExemptCodeSection>501(C)(3)</ExemptCodeSection>
        <PublicCharityStatus>LINE 11A, I</PublicCharityStatus>
        <DirectControllingEntityName>
          <BusinessNameLine1>FRED HUTCHINSON CANCER RESEARCH CENTER</BusinessNameLine1>
        </DirectControllingEntityName>
        <ControlledOrg>1</ControlledOrg>
      </Form990ScheduleRPartII>
      <Form990ScheduleRPartII>
        <NameOfDisregardedEntity>
          <BusinessNameLine1>HUTCHINSON CENTER RESEARCH INSTITUTE OF UGANDA LTD</BusinessNameLine1>
        </NameOfDisregardedEntity>
        <AddressForeign>
          <AddressLine1>POB 3935 MULAGO HOSPITAL UPPER MU</AddressLine1>
          <City>KAMPALA</City>
          <Country>UG</Country>
        </AddressForeign>
        <PrimaryActivities>RESEARCH, EDUCATION AND TREATMENT OF CANCER AND INFECTIOUS DISEASES</PrimaryActivities>
        <LegalDomicileForeignCountry>UG</LegalDomicileForeignCountry>
        <ExemptCodeSection>N/A</ExemptCodeSection>
        <PublicCharityStatus>N/A</PublicCharityStatus>
        <DirectControllingEntityName>
          <BusinessNameLine1>FRED HUTCHINSON CANCER RESEARCH CENTER</BusinessNameLine1>
        </DirectControllingEntityName>
        <ControlledOrg>1</ControlledOrg>
      </Form990ScheduleRPartII>
      <Form990ScheduleRPartII>
        <NameOfDisregardedEntity>
          <BusinessNameLine1>HUTCHINSON CENTER RESEARCH INSTITUTE OF SOUTH AFRICA</BusinessNameLine1>
        </NameOfDisregardedEntity>
        <AddressForeign>
          <AddressLine1>6TH FLOOR 119 HERTZOG BLVD</AddressLine1>
          <City>FORESHORE, CAPETOWN</City>
          <Country>SF</Country>
          <PostalCode>8001</PostalCode>
        </AddressForeign>
        <PrimaryActivities>RESEARCH</PrimaryActivities>
        <LegalDomicileForeignCountry>SF</LegalDomicileForeignCountry>
        <ExemptCodeSection>N/A</ExemptCodeSection>
        <PublicCharityStatus>N/A</PublicCharityStatus>
        <DirectControllingEntityName>
          <BusinessNameLine1>FRED HUTCHINSON CANCER RESEARCH CENTER</BusinessNameLine1>
        </DirectControllingEntityName>
        <ControlledOrg>1</ControlledOrg>
      </Form990ScheduleRPartII>
      <Form990ScheduleRPartIV>
        <NameOfRelatedOrg>
          <BusinessNameLine1>CHARITABLE REMAINDER TRUSTS (5)</BusinessNameLine1>
        </NameOfRelatedOrg>
        <AddressUS>
          <AddressLine1>1100 FAIRVIEW AVE NORTH</AddressLine1>
          <City>SEATTLE</City>
          <State>WA</State>
          <ZIPCode>981091024</ZIPCode>
        </AddressUS>
        <PrimaryActivity>INVESTMENT</PrimaryActivity>
        <LegalDomicileState>WA</LegalDomicileState>
        <DirectControllingEntityNA>N/A</DirectControllingEntityNA>
        <TypeOfEntity>T</TypeOfEntity>
        <ControlledOrg>0</ControlledOrg>
      </Form990ScheduleRPartIV>
      <ReceiptOfIntAnnRentsRoyalties>0</ReceiptOfIntAnnRentsRoyalties>
      <GiftGrantOrCapContrToOtherOrg>0</GiftGrantOrCapContrToOtherOrg>
      <GiftGrantOrCapContrFrOtherOrg>0</GiftGrantOrCapContrFrOtherOrg>
      <LoansOrGuaranteesToOtherOrg>0</LoansOrGuaranteesToOtherOrg>
      <LoansOrGuaranteesFromOtherOrg>0</LoansOrGuaranteesFromOtherOrg>
      <DividendsRelatedOrganization>0</DividendsRelatedOrganization>
      <SaleOfAssetsToOtherOrg>0</SaleOfAssetsToOtherOrg>
      <PurchaseOfAssetsFromOtherOrg>0</PurchaseOfAssetsFromOtherOrg>
      <ExchangeOfAssets>0</ExchangeOfAssets>
      <RentalOfFacilitiesToOtherOrgs>0</RentalOfFacilitiesToOtherOrgs>
      <RentalOfFacilitiesFrOtherOrgs>0</RentalOfFacilitiesFrOtherOrgs>
      <PerformOfServicesForOtherOrgs>1</PerformOfServicesForOtherOrgs>
      <PerformOfServicesByOtherOrgs>0</PerformOfServicesByOtherOrgs>
      <SharingOfFacilities>0</SharingOfFacilities>
      <SharingOfPaidEmployees>0</SharingOfPaidEmployees>
      <ReimbursementPaidToOtherOrg>1</ReimbursementPaidToOtherOrg>
      <ReimbursementPaidByOtherOrg>0</ReimbursementPaidByOtherOrg>
      <OtherTransferToOtherOrg>1</OtherTransferToOtherOrg>
      <OtherTransferFromOtherOrg>0</OtherTransferFromOtherOrg>
      <TransactionsRelatedOrgsTable>
        <NameOfOtherOrganization>
          <BusinessNameLine1>HUTCHINSON CENTER RESEARCH INSTITUTE OF UGANDA LTD</BusinessNameLine1>
        </NameOfOtherOrganization>
        <TransactionType>L</TransactionType>
        <AmountInvolved>69764</AmountInvolved>
        <MethodOfAmtDetermination>ACCOUNTING SYSTEM CODING</MethodOfAmtDetermination>
      </TransactionsRelatedOrgsTable>
      <TransactionsRelatedOrgsTable>
        <NameOfOtherOrganization>
          <BusinessNameLine1>HUTCHINSON CENTER RESEARCH INSTITUTE OF UGANDA LTD</BusinessNameLine1>
        </NameOfOtherOrganization>
        <TransactionType>P</TransactionType>
        <AmountInvolved>1187578</AmountInvolved>
        <MethodOfAmtDetermination>ACCOUNTING SYSTEM CODING</MethodOfAmtDetermination>
      </TransactionsRelatedOrgsTable>
      <TransactionsRelatedOrgsTable>
        <NameOfOtherOrganization>
          <BusinessNameLine1>HUTCHINSON CENTER RESEARCH INSTITUTE OF UGANDA LTD</BusinessNameLine1>
        </NameOfOtherOrganization>
        <TransactionType>R</TransactionType>
        <AmountInvolved>2371522</AmountInvolved>
        <MethodOfAmtDetermination>ACCOUNTING SYSTEM CODING</MethodOfAmtDetermination>
      </TransactionsRelatedOrgsTable>
      <TransactionsRelatedOrgsTable>
        <NameOfOtherOrganization>
          <BusinessNameLine1>HUTCHINSON CENTER RESEARCH INSTITUTE OF SOUTH AFTICA</BusinessNameLine1>
        </NameOfOtherOrganization>
        <TransactionType>L</TransactionType>
        <AmountInvolved>502842</AmountInvolved>
        <MethodOfAmtDetermination>ACCOUNTING SYSTEM CODING</MethodOfAmtDetermination>
      </TransactionsRelatedOrgsTable>
    </IRS990ScheduleR>
  </ReturnData>
</Return>