2012-11-14T10:15:40-06:00 2011-12-31 135665207 KPMG LLP 4200 WELLS FARGO CTR 90 SO 7TH STRE MINNEAPOLIS MN 55402 990 2011-01-01 411670163 HEALTHPARTNERS RESEARCH FOUNDATION HEAL 9528836584 8170 33RD AVENUE SOUTH PO BOX 1309 MINNEAPOLIS MN 554401309 DAVID A DZIUK 9528836584 2012-11-14 1 JASON DIVINE P01076050 6123055000 2011 2016-02-24 21:20:13Z DAVID A DZIUK 8170 33RD AVENUE SOUTH PO BOX 1309 MINNEAPOLIS MN 554401309 17701804 0 X WWW.HPRF.ORG X 1997 MN SEE SCHEDULE O - EXEMPT PURPOSE AND ACHIEVEMENTS 14 4 0 4 0 0 2194408 2132534 14481818 15217240 333775 352030 0 0 17010001 17701804 163 0 0 0 11506453 12684202 0 0 50000 4298320 5050276 15804936 17734478 1205065 -32674 16118175 14898691 1528061 1953417 14590114 12945274 X TO DISCOVER AND ACCELERATE THE USE OF KNOWLEDGE TO IMPROVE THE HEALTH AND HEALTHCARE OF OUR MEMBERS, PATIENTS, AND COMMUNITY. 0 0 11879113 15217240 SEE SCHEDULE O - EXEMPT PURPOSE AND ACHIEVEMENTS 11879113 1 1 0 1 0 0 0 0 0 0 1 0 0 0 0 0 1 1 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 1 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 X 14 4 0 0 0 0 1 1 1 1 1 0 0 1 1 1 1 1 1 1 1 0 MN X X DAVE A DZIUK HEALTHPARTNERS SENIOR VP & CFO 9528836535 8170 33RD AVE S PO BOX 1309 MINNEAPOLIS MN 554401309 X TOM BRINSKO 0.40 X 0 23000 0 JOHN FINNEGAN JR PHD 0.60 X 0 0 0 MARCIA HANSON 0.60 X 0 0 0 ANN WYNIA 0.60 X 0 31750 0 ALAN V ABRAMSON 44.00 X 0 448250 128266 DAVID J DRIES 70.00 X 0 874356 92407 DAVID A DZIUK 55.00 X X 0 496227 142985 GRETCHEN M LEITERMAN 55.00 X 0 258677 61705 BRIAN C MARTINSON PHD 46.00 X 0 131662 50347 J DANIEL NELSON MD 50.00 X 0 550011 121445 CARL A PATOW MD MPH 50.00 X 0 382449 89290 BRIAN H RANK MD 55.00 X X 0 662003 167206 LEIF I SOLBERG MD 55.00 X 0 279458 96418 DONNA J ZIMMERMAN 55.00 X 0 253174 81249 ANDREW F NELSON MPH 61.00 X 0 241817 93360 TOBI TANZER 50.00 X 0 235327 81845 BARBARA E TRETHEWAY 55.00 X 0 506709 126913 0 5374870 1333436 0 0 1 0 KAISER FOUNDATION RESEARCH INSTITUTE 1800 HARRISON ST 16TH FLOOR OAKLAND CA 946123433 SUB CONTRACTOR 659931 UNIVERSITY OF MINNESOTA 1300 S 2ND ST ROOM 655 MINNEAPOLIS MN 55454 SUB CONTRACTOR 393868 UNIVERSITY OF WASHINGTON BOX 355872 SEATTLE WA 98195 SUB CONTRACTOR 242718 GROUP HEALTH COOPERATIVE 1730 MINOR AVE SUITE 1 SEATTLE WA 98101 SUB CONTRACTOR 155883 4 1995996 136538 2132534 MEDICAL RESEARCH 541700 15217240 15217240 15217240 352030 352030 17701804 15217240 0 352030 893062 893062 9108179 6758565 2349614 2682961 1874740 808221 112215 112215 521256 570 470686 50000 54536 43989 10547 176793 96032 80761 146285 16611 129674 621370 135952 485418 226401 142804 83597 92927 56273 36654 52 52 185343 31455 153888 493 493 RESEARCH 1963818 1961883 1935 BAD DEBT 665733 665733 MISCELLANEOUS 152380 27274 125106 FEES 68880 6157 62723 61794 61075 719 17734478 11879113 5805365 50000 2542 51434 370 379 3191516 2821699 14863 15334 2536714 2031153 342411 505561 10962207 10963750 1604266 540534 16118175 14898691 1489082 1944444 38979 8973 1528061 1953417 X 12392392 11380207 2197722 1565067 14590114 12945274 16118175 14898691 X -32674 -1612166 X 0 1 1 X 1 1 X X X X 0 0 0 GROUP HEALTH PLAN INC 410797853 170(B)(1) (A)(III) 1 0 REGIONS HOSPITAL 410956618 170(B)(1) (A)(III) 1 0 2 0 RESTRICTED RESTRICTED RESTRICTED RESTRICTED RESTRICTED RESTRICTED RESTRICTED RESTRICTED 0 0 0 0 0 0 0 0 1 0 0 0 EXPLANATION OF OTHER LOBBYING ACTIVITIES: PART II-B, LINE 1I: HEALTHPARTNERS RESEARCH FOUNDATION PAYS FOR CERTAIN CORPORATE PROFESSIONAL ASSOCIATION MEMBERSHIPS. A PORTION OF SUCH MEMBERSHIP DUES POTENTIALLY COULD BE USED BY THE PROFESSIONAL ASSOCIATIONS FOR LOBBYING ACTIVITIES. 2536714 2031153 505561 505561 17701804 17734478 -32674 -1612166 -1612166 -1644840 17701804 0 17701804 0 17701804 17734478 0 17734478 0 17734478 PART XI, LINE 8 - OTHER ADJUSTMENTS: FASB 136 - BENEFICIAL INTEREST IN NET ASSETS OF REGIONS HOSPITAL FOUNDATION -1,271,429. FASB 124 - FAIR MARKET VALUATION ADJUSTMENT -340,737. TOTAL TO SCHEDULE D, PART XI, LINE 8: -1,612,166. X X X X 0 1 0 0 0 0 1 0 0 ALAN V ABRAMSON 0 327380 0 89180 0 31690 0 40109 0 88157 0 576516 0 13876 DAVID J DRIES 0 848629 0 15180 0 10547 0 0 0 92407 0 966763 0 0 DAVID A DZIUK 0 373036 0 100240 0 22951 0 53153 0 89832 0 639212 0 11553 GRETCHEN M LEITERMAN 0 211125 0 47552 0 0 0 0 0 61705 0 320382 0 0 BRIAN C MARTINSON PHD 0 119287 0 12375 0 0 0 0 0 50347 0 182009 0 0 J DANIEL NELSON MD 0 414503 0 28000 0 107508 0 0 0 121445 0 671456 0 107508 CARL A PATOW MD MPH 0 316626 0 65823 0 0 0 0 0 89290 0 471739 0 0 BRIAN H RANK MD 0 464574 0 130231 0 67198 0 83203 0 84003 0 829209 0 29218 LEIF I SOLBERG MD 0 246742 0 28000 0 4716 0 0 0 96418 0 375876 0 0 DONNA J ZIMMERMAN 0 198854 0 54320 0 0 0 19358 0 61891 0 334423 0 0 ANDREW F NELSON MPH 0 199573 0 42244 0 0 0 0 0 93360 0 335177 0 0 TOBI TANZER 0 195883 0 39444 0 0 0 0 0 81845 0 317172 0 0 BARBARA E TRETHEWAY 0 372165 0 101493 0 33051 0 53241 0 73672 0 633622 0 18644 PART I, LINE 4B DEFERRED COMPENSATION IN COLUMN C OF SCHEDULE J, PART II INCLUDES AMOUNTS FROM A NONQUALIFIED 457(F) PLAN FOR THE FOLLOWING DIRECTORS AND OFFICERS: ALAN V. ABRAMSON $ 12,659 DAVID A. DZIUK 16,629 BRIAN H. RANK 25,775 BARBARA E. TRETHEWAY 16,656 DONNA J. ZIMMERMAN 17,822 -------- TOTAL $ 89,541 PART I, LINE 6 ALL HEALTHPARTNERS RESEARCH FOUNDATION OFFICERS, DIRECTORS AND KEY EMPLOYEES ARE PAID BY GROUP HEALTH PLAN, INC., A RELATED ORGANIZATION, WHICH HAS AN INCENTIVE PROGRAM BY WHICH ALL MANAGERS AND ABOVE ARE ELIGIBLE FOR AN ANNUAL INCENTIVE PAYMENT BASED ON THE ATTAINMENT OF PEOPLE, HEALTH, EXPERIENCE AND STEWARDSHIP GOALS SET BY THE BOARD OF DIRECTORS (EXECUTIVE COMMITTEE). THE ACTUAL ANNUAL PAYMENT IS DETERMINED BY THE LEVEL OF GOAL ATTAINMENT. STEWARDSHIP GOALS ARE TIED TO THE ANNUAL BUDGET. A NET MARGIN THRESHOLD MUST BE MET FOR ANY PAYMENT TO BE MADE FROM THE PROGRAM. ADDITIONALLY, THERE IS A CAP ON THE AMOUNT OF NET MARGIN USED UNDER THE PLAN AND THERE IS A CAP ON THE MAXIMUM INCENTIVE POTENTIALLY AVAILABLE TO EACH PARTICIPANT. EXEMPT PURPOSE AND ACHIEVEMENTS FORM 990, PART III, LINE 4A I. ORGANIZATION AND GOVERNANCE THE HEALTHPARTNERS RESEARCH FOUNDATION (HPRF) IS A MINNESOTA NONPROFIT CORPORATION RECOGNIZED AS EXEMPT FROM FEDERAL INCOME TAX UNDER INTERNAL REVENUE CODE (IRC) SECTION 501(C)(3). HPRF IS RECOGNIZED AS A PUBLIC CHARITY UNDER IRC SECTION 509(A)(3) AS A SUPPORTING ORGANIZATION TO GROUP HEALTH PLAN, INC. (GHI), A MINNESOTA NONPROFIT CORPORATION AND LICENSED HEALTH MAINTENANCE ORGANIZATION (HMO), AND TO REGIONS HOSPITAL, A MINNESOTA NONPROFIT CORPORATION AND LICENSED HOSPITAL, BOTH OF WHICH ARE RECOGNIZED AS EXEMPT FROM FEDERAL INCOME TAX UNDER IRC SECTION 501(C)(3). FOR INFORMATION ABOUT THE CHARITABLE AND COMMUNITY BENEFIT ACTIVITIES AND ACCOMPLISHMENTS OF HPRF'S SUPPORTED ORGANIZATIONS, SEE THE FORM 990 ANNUAL FILINGS FOR EACH ENTITY. HPRF IS PART OF THE HEALTHPARTNERS FAMILY OF ORGANIZATIONS. SPECIFICALLY, THE SOLE CORPORATE MEMBER OF HPRF IS GHI. GHI IS ALSO THE SOLE CORPORATE MEMBER OF HEALTHPARTNERS CENTRAL MINNESOTA CLINICS, INC. (FORMERLY CENTRAL MINNESOTA GROUP HEALTH, INC.), AND PHYSICIANS NECK & BACK CLINICS, BOTH OF WHICH ARE MINNESOTA NONPROFIT CORPORATIONS RECOGNIZED AS EXEMPT FROM FEDERAL INCOME TAX UNDER IRC SECTION 501(C)(3). HEALTHPARTNERS, INC., A MINNESOTA NONPROFIT CORPORATION AND LICENSED HMO RECOGNIZED AS EXEMPT FROM FEDERAL INCOME TAX UNDER IRC SECTION 501(C)(4), IS THE SOLE CORPORATE MEMBER OF GHI AND ALSO OF THE FOLLOWING ORGANIZATIONS, WHICH ARE ALSO EXEMPT FROM FEDERAL INCOME TAX UNDER IRC SECTION 501(C)(3): HEALTHPARTNERS INSTITUTE FOR MEDICAL EDUCATION, RHSC, INC., AND HPI-RAMSEY. HPI-RAMSEY IS THE SOLE CORPORATE MEMBER OF REGIONS HOSPITAL, REGIONS HOSPITAL FOUNDATION, CAPITAL VIEW TRANSITIONAL CARE CENTER LAKEVIEW HEALTH SYSTEM AND RAMSEY INTEGRATED HEALTH SERVICES (A HOME CARE AGENCY), ALL OF WHICH ARE MINNESOTA NONPROFIT CORPORATIONS EXEMPT FROM FEDERAL INCOME TAX UNDER IRC SECTION 501(C)(3). HPI-RAMSEY IS ALSO THE SOLE CORPORATE MEMBER OF RH-WISCONSIN, INC., A WISCONSIN NON-STOCK CORPORATION EXEMPT FROM FEDERAL INCOME TAX UNDER IRC SECTION 501(C)(3). RH-WISCONSIN, INC. AND GHI ARE CORPORATE MEMBERS OF HUDSON HOSPITAL, INC. AND WESTFIELDS HOSPITAL, INC., WISCONSIN NONPROFIT CORPORATIONS EXEMPT FROM FEDERAL INCOME TAX UNDER IRC SECTION 501(C)(3). RH-WISCONSIN, INC. IS ALSO THE SOLE CORPORATE MEMBER OF WESTERN WISCONSIN EMERGENCY MEDICAL SERVICES COMPANY, AN AMBULANCE SERVICE WHICH IS A WISCONSIN NON-PROFIT CORPORATION EXEMPT FROM FEDERAL INCOME TAX UNDER IRC SECTION 501(C)(3). TOGETHER, THESE CORPORATIONS AND OTHERS FORM THE HEALTHPARTNERS FAMILY OF ORGANIZATIONS. THE HEALTHPARTNERS FAMILY OF EXEMPT ORGANIZATIONS SEEK TO BE THE BEST AND MOST TRUSTED PROVIDERS OF HEALTH CARE, HEALTH PROMOTION, HEALTH CARE FINANCING, AND HEALTH CARE ADMINISTRATION IN THE UNITED STATES. ACTING IN CONCERT, THIS FAMILY OF ORGANIZATIONS INTENDS TO TRANSFORM HEALTH CARE BY DELIVERING OUTSTANDING CARE AND SERVICE CONSISTENT WITH THE "TRIPLE AIM." THE TRIPLE AIM IS AN INITIATIVE OF THE INSTITUTE FOR HEALTHCARE IMPROVEMENT TO HELP HEALTH CARE ORGANIZATIONS SIMULTANEOUSLY IMPROVE THE INDIVIDUAL EXPERIENCE OF CARE, THE HEALTH OF THE POPULATION, AND THE PER-CAPITA COST OF CARE. HPRF WORKS WITH AND SUPPORTS CERTAIN EXEMPT ORGANIZATIONS WITHIN THE HEALTHPARTNERS FAMILY OF ORGANIZATIONS TO ACHIEVE THESE AIMS WITH MAXIMUM EFFICIENCY AND COLLABORATION. FORMED IN 1998 BY THE MERGER OF GROUP HEALTH FOUNDATION AND RAMSEY FOUNDATION, HPRF CONTINUES TO BUILD ON THE LONG HISTORY OF RESEARCH ESTABLISHED BY THE TWO PREVIOUS FOUNDATIONS. HPRF AND THE HEALTHPARTNERS FAMILY OF ORGANIZATIONS ALSO PARTNER WITH HMOS, CARE PROVIDERS, AND NONPROFIT ORGANIZATIONS THROUGHOUT THE REGION AND THE NATION TO INCREASE ACCESS FOR THE UNDERSERVED, CREATE AND DISSEMINATE RESEARCH AND CARE-IMPROVEMENT INFORMATION, PARTICIPATE IN THE DEVELOPMENT OF PUBLIC POLICY, AND MAXIMIZE SHARED RESOURCES FOR THE IMPROVEMENT OF THE HEALTH CARE SYSTEM AND THE COMMUNITY'S OVERALL HEALTH. II. RESEARCH ACTIVITIES HPRF'S MISSION IS TO DISCOVER AND ACCELERATE THE USE OF KNOWLEDGE TO IMPROVE THE HEALTH AND HEALTH CARE OF OUR MEMBERS, PATIENTS, AND COMMUNITY. HPRF SEEKS TO IMPROVE HEALTH AND HEALTH CARE THROUGH THE IMPLEMENTATION OF RESEARCH FINDINGS. RESEARCH AREAS OF FOCUS IN HPRF ARE CHRONIC DISEASE, CRITICAL CARE, CHILD AND MATERNAL HEALTH, HEALTH ECONOMICS, HEALTH SERVICES, MENTAL HEALTH, NEUROSCIENCE AND ALZHEIMER'S DISEASE, AND ORAL HEALTH. IN 2011, HPRF WAS INVOLVED IN MORE THAN 200 RESEARCH PROJECTS. AN OVERVIEW OF SOME PROJECT AREAS FOLLOWS. HEALTH BEHAVIORS IN 2011, HPRF CONDUCTED THE FOLLOWING STUDIES FOCUSED ON HEALTH BEHAVIORS: - OBESITY PREVENTION IN CHILDREN - FUNDED BY THE NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASE, THE HEALTHY HOMES/HEALTHY KIDS: PEDIATRIC PRIMARY CARE-BASED OBESITY PREVENTION STUDY EVALUATES THE LONG-TERM EFFICACY OF A PEDIATRIC PRIMARY CARE-BASED OBESITY-PREVENTION INTERVENTION FOR AT-RISK 5- TO 9-YEAR-OLD CHILDREN. A SIMILAR STUDY FUNDED BY THE NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASE IN AT-RISK PRESCHOOL-AGE CHILDREN IS ALSO ONGOING, AS IS A NATIONAL INSTITUTE OF CHILD HEALTH AND DEVELOPMENT/NATIONAL INSTITUTES OF HEALTH-FUNDED STUDY WITH THE MINNESOTA CENTER FOR CHILDHOOD OBESITY PREVENTION, LINKING PRIMARY CARE, COMMUNITY & FAMILY (NET-WORKS). - MAINTAINING WEIGHT LOSS - KEEP IT OFF, AN ONGOING STUDY THAT BEGAN IN 2006, IS FUNDED WITH A $1.75 MILLION GRANT FROM THE NATIONAL CANCER INSTITUTE TO STUDY HOW PEOPLE CAN MAINTAIN WEIGHT LOSS OVER THE LONG TERM. THE STUDY IDENTIFIES THE MOST SUCCESSFUL METHODS FOR ADULTS WHO HAVE INTENTIONALLY LOST 10 PERCENT OF THEIR BODY WEIGHT IN THE PAST YEAR TO MAINTAIN THEIR NEW, HEALTHIER WEIGHT. - PREVENTIVE SERVICES THAT IMPROVE HEALTH BEHAVIORS - UNDER THE GUIDANCE OF THE NATIONAL COMMISSION ON PREVENTION PRIORITIES AND IN COLLABORATION WITH THE PARTNERSHIP FOR PREVENTION, TWO STUDIES ARE DEFINING THE VALUE OF PREVENTIVE SERVICES THAT IMPROVE HEALTH BEHAVIORS. PRIORITIES FOR CLINICAL PREVENTIVE SERVICES, NOW IN ITS 11TH YEAR, AND MEASURING AND COMPARING THE VALUE OF COMMUNITY PREVENTIVE SERVICES, WHICH BEGAN IN 2008, GUIDE DECISION MAKERS ABOUT THE RELATIVE VALUE OF PREVENTIVE INTERVENTIONS. CHRONIC DISEASE DIABETES, HYPERTENSION AND CARDIOVASCULAR RISK REDUCTION IS AN AREA OF STRENGTH IN HPRF. IN 2011, HPRF INVESTIGATORS LED AND WERE INVOLVED IN THE FOLLOWING STUDIES: DIABETES - SIMULATED DIABETES TRAINING FOR RESIDENT PHYSICIANS - THIS STUDY AIMS TO IMPROVE THE SAFETY AND EFFECTIVENESS OF DIABETES CARE DELIVERED BY PRIMARY CARE RESIDENTS THROUGH A SIMULATED LEARNING INTERVENTION THAT OVERCOMES A NUMBER OF CURRENT OBSTACLES TO OUTPATIENT DIABETES CARE TRAINING IN PRIMARY CARE RESIDENCY PROGRAMS. - SUPREME - IN THE BUILDING NEW CLINICAL INFRASTRUCTURE FOR COMPARATIVE EFFECTIVENESS RESEARCH STUDY, WE ARE ADDRESSING WHETHER INTENSIVE GLYCEMIC CONTROL IN ADULT PATIENTS WITH TYPE 2 DIABETES LEADS TO BETTER SHORT- AND LONGER-TERM OUTCOMES THAN LESS INTENSIVE THERAPY AND DETERMINING WHETHER ITS BENEFIT VARIES AS A FUNCTION OF AGE, PREVIOUS CARDIOVASCULAR DISEASE, BLOOD PRESSURE OR LOW-DENSITY LIPOPROTEIN (LDL) CHOLESTEROL CONTROL. WE ARE USING OBSERVATIONAL LONGITUDINAL ANALYSES IN A POOLED CLINICAL COHORT OF 500,000 PATIENTS AND SECONDARY ANALYSES USING AN INSTRUMENTAL VARIABLE. HYPERTENSION - PEDIATRIC HYPERTENSION AND OBESITY - A MULTICENTER STUDY LED BY HPRF AND INCLUDING KAISER PERMANENTE IN COLORADO AND NORTHERN CALIFORNIA, TO EXAMINE PREDICTORS OF AND PATTERNS OF CARE REGARDING PEDIATRIC HYPERTENSION AND OBESITY. IT BEGAN IN 2009 AND IS FUNDED BY THE NATIONAL HEART, LUNG AND BLOOD INSTITUTE. - CARDIOVASCULAR RESEARCH NETWORK (CVRN) MENTAL HEALTH SUPPLEMENT - THIS PROJECT LEVERAGES THE UNIQUE MULTICENTER RESEARCH COLLABORATION OF CVRN WITH PARTICIPATING SITES CONTRIBUTING COMPLEMENTARY EXPERTISE AND, COLLECTIVELY, VERY LARGE, DIVERSE POPULATIONS. THE WORK IS EXAMINING THE RELATIONSHIP BETWEEN THREE PREVALENT MENTAL HEALTH DISORDERS (DEPRESSION, ANXIETY DISORDERS, AND ATTENTION DEFICIT HYPERACTIVITY DISORDER), THEIR ASSOCIATED THERAPIES, AND OUTCOMES FOR HYPERTENSION, ATRIAL FIBRILLATION AND VENOUS THROMBOEMBOLIC DISEASE WITHIN THE NATIONAL HEART, LUNG AND BLOOD INSTITUTE-SPONSORED CVRN. THESE OUTCOMES INCLUDE INTERMEDIATE MARKERS SUCH AS MEDICATION ADHERENCE, SURROGATE OUTCOMES, AND LONG-TERM CLINICAL OUTCOMES. - SIMCARE HYPERTENSION - A "PERSONALIZED PHYSICIAN LEARNING" APPROACH THAT ASSESSES THE IMPACT OF TWO INTERVENTIONS FOR REDUCING HYPERTENSION IN A PRIMARY CARE SETTING. THE FIRST INTERVENTION, REAL-PPL, USES REAL EMR-DERIVED DATA TO DIRECT PERSONALIZED LEARNING. THE SECOND INTERVENTION, SIM-PPL, USES PHYSICIAN PERFORMANCE IN SIMULATED CASES. THE REAL-PPL AND SIM-PPL ASSESSMENT DATA ARE USED TO IDENTIFY EACH PHYSICIAN'S PATTERN OF THERAPEUTIC INERTIA AND FAILURES OF DECISION MAKING IN HYPERTENSION. PHYSICIANS ARE THEN ASSIGNED AND DELIVERED 12 SIMULATED HYPERTENSION LEARNING CASES THAT CORRESPOND TO THE TREATMENT FAILURES IDENTIFIED. THE LEARNING CASES ARE DELIVERED VIA THE WEB, EMBODY PRINCIPLES OF ADAPTIVE LEARNING, AND PROVIDE THREE KINDS OF LEARNING FEEDBACK (ACTUAL BLOOD PRESSURE VALUES, GRAPHIC DATA DISPLAYS, AND SPECIFIC CLINICAL MANAGEMENT SUGGESTIONS). CARDIOVASCULAR - PRIORITIZED CLINICAL DECISION SUPPORT TO REDUCE CARDIOVASCULAR (CV) RISK - THE OBJECTIVE OF THIS PROJECT IS TO DEVELOP AND IMPLEMENT POINT-OF-CARE ELECTRONIC HEALTH RECORD (EHR)-DRIVEN DECISION SUPPORT THAT IDENTIFIES AND PRIORITIZES AVAILABLE EVIDENCE-BASED CLINICAL OPTIONS TO REDUCE CV RISK IN MODERATE- TO HIGH- RISK ADULTS. THIS APPROACH, IF SUCCESSFUL, WILL (A) IMPROVE CHRONIC DISEASE OUTCOMES, (B) USHER IN THE ERA OF PERSONALIZED MEDICINE, (C) MAXIMIZE THE CLINICAL RETURN ON THE MASSIVE INVESTMENTS THAT ARE INCREASINGLY BEING MADE IN SOPHISTICATED OUTPATIENT EHR SYSTEMS, AND (D) REDUCE THE "PIPELINE" OF CV RISK TO SUSTAIN DECADES-LONG IMPROVEMENT TRENDS IN CV EVENTS AND CV MORTALITY IN THE UNITED STATES. THIS PROJECT IS FUNDED BY THE NATIONAL HEART, LUNG AND BLOOD INSTITUTE. TREATMENT OF PULMONARY CONDITIONS AND DISEASE IN 2011, HPRF PULMONARY SPECIALISTS PARTICIPATED IN THE CHRONIC PULMONARY DISEASE CLINICAL RESEARCH NETWORK, A CONSORTIUM OF 10 CLINICAL CENTERS AND A COORDINATING CENTER AT THE UNIVERSITY OF MINNESOTA. ACTIVE STUDIES INCLUDE: - CHRONIC OBSTRUCTIVE PULMONARY DISEASE (COPD) - THE NATIONAL INSTITUTES OF HEALTH (NIH)-FUNDED STUDY, MULTICOMPONENT INTERVENTION TO DECREASE CHRONIC OBSTRUCTIVE PULMONARY DISEASE-RELATED HOSPITALIZATIONS. - AN OBSERVATIONAL STUDY FUNDED BY THE NIH DESIGNED TO DISCOVER GENETIC FACTORS THAT MIGHT PREDICT COPD. THE RESEARCHERS ARE ALSO ASSESSING GENETIC FACTORS ASSOCIATED WITH OTHER SMOKING-RELATED DISORDERS (E.G., CANCER, HEART/VASCULAR DISEASE). MENTAL HEALTH IN 2011, HPRF RESEARCHERS WERE ACTIVE IN IMPORTANT DEPRESSION STUDIES. - THE DIAMOND STUDY - A COMPREHENSIVE EVALUATION OF A GROUNDBREAKING INITIATIVE TO CHANGE THE WAY MINNESOTANS RECEIVE TREATMENT FOR DEPRESSION. THE NATIONAL INSTITUTE OF MENTAL HEALTH AWARDED HPRF A $3 MILLION GRANT FOR DIAMOND, WHICH IS LED BY MINNESOTA'S INSTITUTE FOR CLINICAL SYSTEMS IMPROVEMENT. COMPONENTS OF THE NEW PROGRAM INCLUDE USE OF A STANDARD ASSESSMENT TOOL TO IMPROVE THE DIAGNOSIS AND MANAGEMENT OF DEPRESSION, THE ADDITION OF A CARE MANAGER TO THE PATIENT'S TREATMENT TEAM FOR MORE PERSONALIZED CARE, AND A TRACKING SYSTEM TO MONITOR FOLLOW-UP CARE AND TREATMENT EFFECTIVENESS. THE DIAMOND DEPRESSION CARE MODEL WAS IMPLEMENTED IN ABOUT 85 PRIMARY CARE MEDICAL CLINICS ACROSS MINNESOTA IN 2008 AND 2009. DIAMOND IS LED BY HPRF IN CLOSE PARTNERSHIP WITH DIAMOND INITIATIVE LEADERS AND NATIONAL RESEARCH EXPERTS. THE STUDY IS EVALUATING CHANGES IN PATIENT CARE, PATIENT OUTCOMES, PATIENT CARE COST AND UTILIZATION, THE COST TO CLINICS AND HEALTH PLANS TO IMPLEMENT THE CARE MODEL, AND CLINIC FACTORS IMPORTANT TO SUCCESS. - THE MENTAL HEALTH RESEARCH NETWORK STUDY A POPULATION-BASED APPROACH TO TRANSFORM RESEARCH: SUBPROJECT PERINATAL DEPRESSION HEALTH ECONOMICS HPRF'S HEALTH ECONOMICS TEAM HAS A HISTORY AS THE ANALYSIS GROUP FOR THE NATIONAL COMMISSION ON PREVENTION PRIORITIES. THE TEAM HAS BEEN RECOGNIZED FOR ITS COST-EFFECTIVENESS MODELING EXPERIENCE, KNOWLEDGE OF EVIDENCE-BASED PREVENTIVE CARE, AND A SET OF MODELS BUILT FOR FUTURE WORK. THE TEAM IS ALSO THE LEAD SITE FOR THE COST-EFFECTIVENESS ANALYSIS PROJECT IN A STUDY OF COLORECTAL CANCER GENETICS. ANOTHER RECOGNIZED STRENGTH IS ECONOMETRIC ANALYSIS OF CLAIMS DATA. THE TEAM ALSO HAS EXPERTISE IN CLINIC OPERATIONS AND ELECTRONIC MEDICAL RECORDS ANALYSIS. - QUANTIFYING THE IMPACT OF NATIONAL POLICIES ON CHILDHOOD OBESITY, FUNDED BY THE AETNA FOUNDATION THROUGH THE PARTNERSHIP FOR PREVENTION. - PRIORITIES AMONG RECOMMENDED CLINICAL PREVENTIVE SERVICES: PHASE III, FUNDED BY THE CENTERS FOR DISEASE CONTROL THROUGH THE PARTNERSHIP FOR PREVENTION. - MEASURING AND COMPARING THE VALUE OF COMMUNITY PREVENTIVE SERVICES TO INCREASE THE IMPACT OF PUBLIC HEALTH AGENCIES, FUNDED BY THE ROBERT WOOD JOHNSON FOUNDATION THROUGH THE PARTNERSHIP FOR PREVENTION. - COMPARATIVE EFFECTIVENESS RESEARCH IN GENOMICS & PERSONALIZED MEDICINE OF COLORECTAL CANCER, FUNDED BY THE NATIONAL CANCER INSTITUTE THROUGH THE CENTER FOR HEALTH RESEARCH, KAISER PERMANENTE NORTHWEST. NEUROSCIENCE AND ALZHEIMER'S DISEASE RESEARCH HPRF'S ALZHEIMER'S RESEARCH CENTER AT REGIONS HOSPITAL IS INTERNATIONALLY KNOWN FOR PIONEERING RESEARCH ON THE TREATMENT AND PREVENTION OF ALZHEIMER'S DISEASE, PARKINSON'S DISEASE, STROKE AND OTHER BRAIN DISORDERS. IN 2011, ALZHEIMER'S RESEARCH CENTER INVESTIGATORS WORKED ON 15 STUDIES. THE ALZHEIMER RESEARCH CENTER, WHICH MAINTAINS ONE OF THE WORLD'S LARGEST HUMAN BRAIN BANKS FOR RESEARCH, FOCUSES ON CLINICAL TRIALS, THE DEVELOPMENT OF A PATIENT REGISTRY TO STUDY MEMORY, AND THE DEVELOPMENT OF DRUGS AND DRUG-DELIVERY METHODS (E.G., NOSE DROPS, INTRANASAL SPRAYS). THIS DELIVERY METHOD PROTECTS THE PARTS OF THE BRAIN ESSENTIAL FOR MEMORY AND LEARNING WHILE AVOIDING THE SIDE EFFECTS OF OTHER METHODS. CENTER RESEARCHERS COLLABORATE WITH 40 RESEARCHERS WORLDWIDE WHO ARE USING THE INTRANASAL TREATMENT METHOD IN THEIR OWN RESEARCH. THE ALZHEIMER'S RESEARCH CENTER'S ABILITY TO CONDUCT CLINICAL RESEARCH IS ENHANCED BY ITS RELATIONSHIP WITH THE CENTER FOR DEMENTIA AND ALZHEIMER'S CARE (CDAC) IN REGIONS HOSPITAL AND HEALTHPARTNERS. EXAMPLES OF CURRENT WORK AT THE ALZHEIMER'S RESEARCH CENTER INCLUDE: - STUDIES OF DRUGS GIVEN INTRANASALLY (E.G., DEFEROXAMINE, INSULIN, AL-108, STEM CELLS) TO SLOW COGNITIVE DECLINE IN ALZHEIMER'S DISEASE. THE CENTER'S INTRANASAL DEFEROXAMINE TREATMENT IS EXPECTED TO BE MARKETED FOR THE TREATMENT OF ALZHEIMER'S IN THE NEXT 5 YEARS AS A RESULT OF AN AGREEMENT WITH A CANADIAN PHARMACEUTICAL COMPANY. THIS DRUG IS ALSO BEING STUDIED AS A TREATMENT FOR OTHER NEUROLOGICAL DISORDERS, SUCH AS STROKE. - MINNESOTA MEMORY PROJECT - THE MINNESOTA MEMORY PROJECT IS A FIRST-OF-ITS-KIND REGISTRY TO TRACK 1,000 AGING ADULTS OF MINNESOTA AND THE SURROUNDING AREAS. IT AIMS TO COLLECT INFORMATION ON MEMORY CHANGES ASSOCIATED WITH AGING IN THE PRESENCE AND ABSENCE OF BRAIN DISEASE; TO COLLECT INFORMATION FROM CAREGIVERS ABOUT THE HEALTH EFFECTS RELATED TO CARING FOR INDIVIDUALS WITH MEMORY LOSS; AND TO CONNECT INTERESTED PARTICIPANTS WITH CUTTING-EDGE RESEARCH STUDIES. ORAL HEALTH AND DENTISTRY HPRF DENTAL RESEARCHERS WERE ACTIVE IN 21 STUDIES IN 2011, 15 OF THEM THROUGH THE DENTAL PRACTICE-BASED RESEARCH NETWORK (DPBRN), FUNDED THROUGH THE NATIONAL INSTITUTE OF DENTAL AND CRANIOFACIAL RESEARCH, PART OF THE NATIONAL INSTITUTES OF HEALTH. CHILD AND MATERNAL HEALTH RESEARCH IN THIS AREA HAS BEEN CONDUCTED AT HPRF FOR MANY YEARS, BUT A MORE FORMAL GROUP WAS STRUCTURED IN 2011. THE GROUP HAS A STRONG INVESTIGATOR GROUP WITH BACKGROUNDS IN CLINICAL PSYCHOLOGY, CLINICAL MEDICINE, AND EPIDEMIOLOGY; AND MAINTAINS STRONG RELATIONSHIPS WITH PEDIATRICS AND OB-GYN HEALTH CARE LEADERS WHO ARE INTERESTED IN RESEARCH PARTNERSHIPS. SOME OF THE WORK THE GROUP IS CONDUCTING INCLUDES: - THE POPULATION-BASED EFFECTIVENESS IN ASTHMA AND LUNG DISEASES (PEAL) NETWORK, FUNDED BY THE NATIONAL HEART, LUNG AND BLOOD INSTITUTE. - FEASIBILITY OF BEHAVIORAL ACTIVATION THERAPY FOR PERINATAL DEPRESSION/AIM (ACTIVE INVOLVED MOMS) FOR WELLNESS, FUNDED BY THE NATIONAL INSTITUTE FOR MENTAL HEALTH - NATIONAL STUDY CENTER FOR THE NATIONAL CHILDREN'S STUDY - DETERMINANTS OF PRE-CONCEPTION, PRENATAL, AND POSTPARTUM HEALTH IN AN URBAN POPULATION, FUNDED BY THE NATIONAL INSTITUTES OF HEALTH - MN CENTER FOR CHILDHOOD OBESITY PREVENTION: LINKING PRIMARY CARE, COMMUNITY & FAMILY (NETWORKS), FUNDED BY NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT. CRITICAL CARE RESEARCH THE DEPARTMENT OF SURGERY FOR HEALTHPARTNERS MEDICAL GROUP AND REGIONS HOSPITAL HAS MORE THAN 20 RESEARCH STUDIES UNDER WAY, INCLUDING RESEARCH ON TRAUMA, CRITICAL CARE, EMERGENCY MEDICAL SERVICES, AND BURNS. IN 2011, HPRF OPENED THE CRITICAL CARE RESEARCH CENTER (CCRC), A CENTER DEVOTED TO CRITICAL CARE RESEARCH ACROSS THE PATIENT CARE CONTINUUM, STARTING WITH THE 911 CALL; THE CCRC IS HOUSED AT REGIONS HOSPITAL. EXTERNAL COLLABORATION THE HMO RESEARCH NETWORK (HMORN) HPRF IS A MEMBER OF HMORN, A COLLABORATIVE OF 19 RESEARCH CENTERS AFFILIATED WITH INTEGRATED HEALTH CARE SYSTEMS. HPRF AND HMORN RESEARCH INVESTIGATORS HAVE WORKED ON FEDERALLY FUNDED PROJECTS SUCH AS THE HMO CANCER RESEARCH NETWORK, THE VACCINE SAFETY DATALINK, THE CENTER FOR EDUCATION AND RESEARCH IN THERAPEUTICS, THE COORDINATED CLINICAL STUDIES NETWORK, THE CARDIOVASCULAR RESEARCH NETWORK, THE DECIDE NETWORK, THE FDA SENTINEL AND THE MENTAL HEALTH RESEARCH NETWORK. MENTAL HEALTH RESEARCH NETWORK (MHRN) SINCE INITIAL FUNDING IN JULY 2010, THE MHRN HAS BEEN WORKING ON UNDERSTANDING VARIATIONS IN THE MENTAL HEALTH DATA IN THE VIRTUAL DATA WAREHOUSE (VDW) IN THE 10 PARTICIPATING ORGANIZATIONS. WE ARE PARTICIPATING IN THE PRACTICE VARIATIONS AND FEASIBILITY OF BEHAVIORAL ACTIVATION THERAPY FOR PERINATAL DEPRESSION/AIM (ACTIVE INVOLVED MOMS) FOR WELLNESS STUDIES; SSRI WARNINGS AND SUICIDE PREVENTION; AND HOW BEST TO ENGAGE HEALTH SYSTEMS IN DETERMINING RESEARCH PRIORITIES. THE MINI-SENTINEL THIS IS A COLLABORATIVE INVOLVING SIX OF THE HMORN CENTER FOR EDUCATION AND RESEARCH ON THERAPEUTICS (CERT) SITES JOINED AS A SINGLE ORGANIZATION IN COLLABORATION WITH 19 OTHER NATIONAL CENTERS AND ORGANIZATIONS UNDER THE DIRECTION OF DR. RICHARD PLATT AT HARVARD PILGRIM HEALTH CARE IN RESPONSE TO AN RFP PUBLISHED BY THE U.S. FOOD AND DRUG ADMINISTRATION TO DEVELOP THE SENTINEL INITIATIVE. THE SENTINEL INITIATIVE IS THE OUTCOME OF A 2008 PUBLICATION TITLED THE SENTINEL INITIATIVE: NATIONAL STRATEGY FOR MONITORING MEDICAL PRODUCT SAFETY. IN 2011, HPRF PARTICIPATED IN THE FOLLOWING MINI-SENTINEL PROJECTS: - CASE IDENTIFICATION, VALIDATION, AND ADJUDICATION OF ANAPHYLAXIS - SIGNAL REFINEMENT OF ANGIOEDEMA EVENTS IN ASSOCIATION WITH USE OF DRUGS THAT ACT ON THE RENIN-ANGIOTENSIN-ALDOSTERINE SYSTEM CANCER RESEARCH NETWORK (CRN) HPRF IS A RECOGNIZED LEADER IN CANCER RESEARCH, WITH A DIVERSE TEAM OF INVESTIGATORS AND ESTABLISHED PARTNERSHIPS AT THE LOCAL, REGIONAL AND NATIONAL LEVEL. IN 2011, HPRF CONTINUED TO CONDUCT STUDIES LOCALLY AND TO ACTIVELY PARTICIPATE IN THE HMO CANCER RESEARCH NETWORK IN A NATIONAL CANCER INSTITUTE (NCI)-FUNDED COLLABORATION OF 14 HEALTH PLANS NATIONWIDE STUDYING CANCER PREVENTION, DIAGNOSIS, AND TREATMENT: - THE COMMUNITY SOCIAL ENVIRONMENT AND THE CANCER CARE CONTINUUM, FUNDED BY THE AMERICAN CANCER SOCIETY. - PLAN: PREPARING FOR LIFE AFTER NEWS OF CANCER WITH SURVIVOR CARE PLANS, FUNDED BY THE AMERICAN CANCER SOCIETY. - LONG-TERM SURVIVORSHIP IN OLDER WOMEN WITH EARLY STAGE BREAST CANCER, FUNDED BY THE NATIONAL CANCER INSTITUTE. CLINICAL AND TRANSLATIONAL SCIENCE INSTITUTE (CTSI) HPRF IS PART OF THE CTSI, WHOSE GOAL IS TO IMPROVE THE HEALTH OF OUR COMMUNITIES BY INTEGRATING THE UNIVERSITY OF MINNESOTA'S ACADEMIC HEALTH CENTER AND OTHER UNIVERSITY RESOURCES WITH COMMUNITY PARTNERS TO CREATE A COMPREHENSIVE STATEWIDE NETWORK FOR CLINICAL AND TRANSLATIONAL SCIENCE. HPRF'S EXECUTIVE DIRECTOR IS THE CTSI'S COMMUNITY ENGAGEMENT DIRECTOR. THROUGH THE CTSI, THESE ORGANIZATIONS AIM TO: - COLLABORATE WITH COMMUNITIES TO IMPROVE HEALTH THROUGH A MODEL THAT CENTERS ON RESEARCH IMPORTANT TO OUR COMMUNITIES - MEET RESEARCHER NEEDS FOR CLINICAL AND TRANSLATIONAL RESEARCH SERVICES THROUGH A SERVICE-ORIENTED RESEARCH PLATFORM - EDUCATE THE NEXT GENERATION OF CLINICAL TRANSLATIONAL SCIENCE RESEARCHERS AND GUIDE CAREER DEVELOPMENT IN CONDUCTING RESEARCH, DEVELOPING COLLABORATIVE, INTERDISCIPLINARY WORK GROUPS, AND IMPLEMENTING FINDINGS INTO PRACTICE SETTINGS CTSI EFFORTS ARE EXPECTED TO ACHIEVE ALIGNMENT WITH MAJOR STATEWIDE HEALTH CARE ORGANIZATIONS AND INSURERS, ELECTRONIC NETWORKS, AND SPECIAL AND RURAL COMMUNITY POPULATIONS, ALONG WITH STRATEGIC INVESTMENTS BY THE UNIVERSITY OF MINNESOTA AND THE STATE OF MINNESOTA TO HAVE A MAJOR STATEWIDE EFFECT ON HEALTH CARE OUTCOMES AND WORKFORCE TRAINING. VACCINE SAFETY DATALINK THE VACCINE SAFETY DATALINK (VSD) - A COLLABORATION AMONG THE CENTERS FOR DISEASE CONTROL AND PREVENTION, AMERICA'S HEALTH INSURANCE PLANS, AND 10 HMOS, INCLUDING HEALTHPARTNERS, TO MONITOR AND ASSESS THE SAFETY OF CHILDHOOD AND ADULT VACCINES. THE EIGHT HMOS CREATE IDENTICAL DATA SETS OF ALL VACCINE EXPOSURES AND ALL MEDICALLY TREATED ILLNESSES, AS WELL AS DEMOGRAPHIC INFORMATION (E.G., DATE OF BIRTH, SEX, RESIDENCE). HPRF RESEARCHERS WERE ACTIVE IN 28 VSD PROJECTS IN 2011, AND HPRF WAS THE LEAD SITE FOR FIVE OF THESE(*): COMPLETED IN 2011: - HENOCH SCHONLEIN PURPURA AND MENINGOCOCCAL VACCINE - INJECTIONS SITE AND LOCAL REACTIONS TO THE FIFTH DIPHTHERIA, TETANUS & PERTUSSIS (DTAP) VACCINATION - RAPID CYCLE ANALYSIS OF PENTAVALENT ROTAVIRUS (ROTATEQ) VACCINE SAFETY ADDED IN 2011: - ACTIVE POST-LICENSURE SAFETY MONITORING OF THE COMBINATION DTAP-IPV/HIB VACCINE (PENTACEL) - TRIVALENT AND MONOVALENT LIVE ATTENUATED INFLUENZA VACCINE (LAIV) USE AND SAFETY AMONG INDIVIDUALS WITH ASTHMA 2008-2011 - DESCRIBING MORTALITY RATES AND CAUSE OF DEATH PATTERNS IN THE VACCINE SAFETY DATALINK - SEIZURES FOLLOWING MULTIPLE VACCINES - SEPARATING EFFECT OF ANTECEDENT INFECTIONS VS. INFLUENZA VACCINATION FOR GUILLAIN-BARRE SYNDROME 2009-2011 CARDIOVASCULAR RESEARCH NETWORK (CVRN) THE CVRN, WHICH INCLUDES 15 HMORN SITES, WAS LAUNCHED IN 2007 THROUGH FUNDING FROM THE NATIONAL HEART, LUNG, AND BLOOD INSTITUTE. THE CVRN CAPITALIZES ON SEVERAL KEY STRENGTHS OF HMORN, INCLUDING ITS BROAD EXPERTISE IN CARDIOVASCULAR MEDICINE, DIVERSE HEALTH PLANS AND POPULATIONS, AND INTEGRATED DATA SYSTEMS. THE CVRN AIMS TO DEVELOP A FRAMEWORK FOR EXPLORING CRITICAL QUESTIONS IN CARDIOVASCULAR EPIDEMIOLOGY AND THE OPTIMAL MANAGEMENT OF CARDIOVASCULAR DISEASE IN LARGE, COMMUNITY-BASED POPULATIONS. HPRF PARTICIPATES IN THE FOLLOWING CVRN SPONSORED PROJECTS: - DEVELOPMENT OF A CARDIOVASCULAR SURVEILLANCE SYSTEM IN THE CVRN - MENTAL HEALTH DISORDERS AND MEDICATION ADHERENCE AND OUTCOMES IN HYPERTENSION, ATRIAL FIBRILLATION, AND VENOUS THROMBOEMBOLISM WITHIN THE CVRN MIDWEST RESEARCH NETWORK HEALTHPARTNERS RESEARCH FOUNDATION WAS ONE OF THE FOUNDING MEMBERS OF THE NEW MIDWEST RESEARCH NETWORK (MWRN) IN 2011. THE NETWORK'S MISSION IS TO COLLABORATE IN THE DEVELOPMENT, IMPLEMENTATION, AND APPLICATION OF RESEARCH THAT IMPROVES THE OUTCOMES, EXPERIENCE, AND AFFORDABILITY OF HEALTH CARE FOR ALL PEOPLE IN OUR (MIDWEST) REGION. MEMBERS OF THE NETWORK INCLUDE RESEARCH ORGANIZATIONS, PROVIDER GROUPS, QUALITY IMPROVEMENT ORGANIZATIONS, GOVERNMENT AGENCIES, AND HEALTH PLANS IN MINNESOTA, NORTH DAKOTA AND WISCONSIN. MEMBERS OF THE GROUP ARE CURRENTLY FOCUSING ON TOPICS SUCH AS AVOIDABLE HOSPITAL READMISSIONS, LOW BACK PAIN, PROVIDER/PATIENT DECISION TOOLS, AND BARIATRIC SURGERY. INTERNAL COLLABORATION BOTH PARTNERSHIP GRANTS AND DISCOVERY GRANTS ARE FUNDED BY DONATIONS TO HPRF THAT ARE MATCHED BY HEALTHPARTNERS. DISCOVERY GRANTS PROVIDE INTERNAL FUNDING FOR PROJECTS THAT HAVE PROMISE FOR FUTURE EXTERNAL FUNDING, ADDRESS CLINICAL AND/OR ORGANIZATIONAL CONCERNS, INVEST IN A NEW RESEARCHER, AND SUPPORT ORGANIZATIONAL AND CLINICAL LEARNING TO IMPROVE PATIENT CARE OR ENHANCE THE ABILITY TO CONDUCT MEANINGFUL RESEARCH. PARTNERSHIP GRANTS AIM TO FOSTER ACTIVE COLLABORATION BETWEEN RESEARCHERS AND OPERATIONAL LEADERS TO ANSWER CRITICAL QUESTIONS ABOUT EXISTING HEALTH PROGRAMS AND PATIENT CARE ISSUES. THIS RESEARCH MAY EVALUATE OR LEAD TO CHANGES IN THE WAY HEALTHPARTNERS DELIVERS OR ADMINISTERS CARE. BOTH PROGRAMS ACTIVELY SUPPORT THE SHARING OF RESULTS IN THE PUBLIC DOMAIN THROUGH PUBLICATION OF FINDINGS IN PEER-REVIEWED JOURNALS. NINE DISCOVERY GRANTS AND ONE PARTNERSHIP GRANT WERE AWARDED IN 2011. 2011 DISCOVERY GRANTS - SARAH ANDERSON, MD: METATARSAL FRACTURES AND VITAMIN D DEFICIENCY - JARED FINE, PHD: INTRANASAL DEFEROXAMINE TREATMENT IN A RAT MODEL OF PARKINSON'S DISEASE - BRAD HERNANDEZ, MD: IMPACT OF TARGETED RAPID HIV TESTING UPON EMERGENCY DEPARTMENT LENGTH OF STAY - MATTHEW KANG, MD: HIGH-RESOLUTION MR IMAGING OF THE HUMAN SPINAL NERVE ROOTS - ELYSE KHARBANDA, MD, MPH: PREGNANCY AMONG INSURED ADOLESCENTS AND MISSED OPPORTUNITIES FOR PREVENTION - MICHAEL MCGONIGAL, MD: GERIATRIC FALLS PREVENTION PROGRAM - KAREN QUADAY, MD: A RETROSPECTIVE DESCRIPTIVE STUDY OF MRI USE IN AN ACADEMIC EMERGENCY DEPARTMENT - LEIF SOLBERG, MD: APPROPRIATENESS AND RESULTS OF ADVANCED DIAGNOSTIC IMAGING ORDERS FOR PATIENTS WITH ABDOMINAL PAIN: A PILOT STUDY - GABRIELA VAZQUEZ-BENITEZ, PHD: PATIENT PERCEPTION OF CARE AND CARE DELIVERY IN ETHNIC MINORITY POPULATIONS AT HEALTHPARTNERS, THE EBAN EXPERIENCE 2011 PARTNERSHIP GRANTS - MICHAEL GOERTZ, MD: BENEFITS FROM AN INNOVATIVE APPROACH TO ACUTE LOW BACK PAIN TREATMENT IN PRIMARY CARE PUBLICATIONS IN 2011, HPRF RESEARCHERS DISSEMINATED THE RESULTS OF THEIR RESEARCH BY PUBLISHING 163 ARTICLES, BOOKS AND BOOK CHAPTERS, AND BY GIVING 276 PAPER AND POSTER PRESENTATIONS AT NATIONAL AND INTERNATIONAL CONFERENCES. FORM 990, PART VI, SECTION A, LINE 6 THE SOLE CORPORATE MEMBER OF HPRF IS GROUP HEALTH PLAN, INC. (GHI), A MINNESOTA NON-PROFIT CORPORATION RECOGNIZED AS EXEMPT FROM FEDERAL INCOME TAX UNDER IRC SECTION 501(C)(3). FORM 990, PART VI, SECTION A, LINE 7A GHI, AS THE SOLE CORPORATE MEMBER, SELECTS AND/OR APPROVES ALL DIRECTORS. FORM 990, PART VI, SECTION A, LINE 7B GHI, AS THE SOLE CORPORATE MEMBER APPROVES ACTIONS AS FOLLOWS: - AMENDMENTS TO THE ARTICLES AND BYLAWS - ANNUAL AND CAPITAL BUDGETS AND LONG-RANGE PLANS - UNBUDGETED SPECIAL PROJECTS IN EXCESS OF $10,000 - GUARANTEEING THE DEBT OF ANY OTHER PERSON OR ENTITY - A LOAN OR OTHER INDEBTEDNESS IN EXCESS OF $10,000 - DISPOSITION OF SUBSTANTIALLY ALL ASSETS - MERGER OR CONSOLIDATION WITH ANOTHER CORPORATION - DISSOLUTION - SELECTION OF OFFICERS FORM 990, PART VI, SECTION B, LINE 11 HPRF'S 990 RETURN HAS A COMPREHENSIVE REVIEW PROCESS THAT IS FOLLOWED BEFORE IT IS PRESENTED TO THE GOVERNING BODY OF HPRF. THE REVIEW PROCESS INCLUDES A LAYERED REVIEW BY THE TAX DEPARTMENT OF GHI, THE MANAGEMENT TEAM OF HPRF, GHI'S INTERNAL LEGAL DEPARTMENT AND HPRF'S OUTSIDE INDEPENDENT ACCOUNTANTS. EACH ONE OF THOSE AREAS HAS AN OPPORTUNITY TO REVIEW, ASK QUESTIONS AND MAKE COMMENTS BACK TO THE TAX DEPARTMENT OF GHI BEFORE THE FORM 990 IS COMPLETED AND PRESENTED TO THE GOVERNING BODY OF HPRF. ONCE THAT REVIEW PROCESS HAS BEEN COMPLETED, IT IS THE POLICY OF HPRF TO MAKE AVAILABLE TO THE FINANCE AND AUDIT COMMITTEE OF THE BOARD OF DIRECTORS AND THE BOARD OF DIRECTORS OF HPRF A COPY OF THE 990 PRIOR TO THE FILING OF THE 990 RETURN. THIS COPY WILL BE PROVIDED IN THE BOARD PACKET OF A FINANCE AND AUDIT COMMITTEE AND BOARD MEETING PRIOR TO THE FILING OF THE 990 AND WILL BE AN AGENDA ITEM AT A BOARD MEETING. THIS PROCESS WILL BE NOTED AND DOCUMENTED IN THE WRITTEN BOARD MINUTES OF THE MEETING. FORM 990, PART VI, SECTION B, LINE 12C HPRF IS GOVERNED BY AN 18 MEMBER BOARD OF DIRECTORS. AS REQUIRED BY THE BYLAWS OF HPRF, THE HPRF BOARD MONITORS POTENTIAL CONFLICTS OF INTEREST ON THE PART OF ITS BOARD MEMBERS, OFFICERS AND KEY EMPLOYEES BY MAINTAINING A CONFLICT OF INTEREST POLICY. UNDER THE POLICY, ALL BOARD MEMBERS, PRINCIPAL OFFICERS, MEMBERS OF A COMMITTEE WITH BOARD DELEGATED POWERS AND KEY EMPLOYEES ANNUALLY ARE PROVIDED WITH A COPY OF THE POLICY AND REQUESTED TO COMPLETE A QUESTIONNAIRE IDENTIFYING ANY POTENTIAL CONFLICTS OF INTEREST. THE GENERAL COUNSEL WILL SUMMARIZE THE FINDINGS FOLLOWING REVIEW OF THE QUESTIONNAIRE AND WILL SUBMIT A REPORT TO THE CHAIR, PRESIDENT AND THE EXECUTIVE DIRECTOR. BOARD AGENDAS AND EXECUTIVE DECISIONS ARE MONITORED IN RELATION TO THIS POLICY. FORM 990, PART VI, SECTION B, LINE 15 PROCESS FOR DETERMINING COMPENSATION OF CEO, OTHER OFFICERS AND KEY EMPLOYEES HPRF HAS NO EMPLOYEES. ALL OFFICERS, DIRECTORS AND KEY EMPLOYEES ARE PAID BY GHI, A RELATED ORGANIZATION WHICH HAS AN ANNUAL PROCESS TO REVIEW THE MARKET COMPARABILITY OF THE TOTAL COMPENSATION OF HPRF'S EXECUTIVE DIRECTOR AND ITS OTHER OFFICERS AND MEDICAL DIRECTORS (MD). EACH YEAR, UNDER THE DIRECTION OF THE GHI BOARD OF DIRECTORS' COMPENSATION COMMITTEE (COMPENSATION COMMITTEE), AN ANNUAL TOTAL COMPENSATION MARKET REVIEW IS COMPLETED. THE REVIEW INCLUDES ALL COMPONENTS OF COMPENSATION; BASE SALARY, ANNUAL INCENTIVES, BENEFITS AND PERQUISITES. THE MARKET SURVEY RESULTS ARE PRESENTED TO, REVIEWED BY AND APPROVED BY THE COMPENSATION COMMITTEE. THE COMPENSATION COMMITTEE'S MARKET REVIEW PROCESS AND SUBSEQUENT DECISIONS INCLUDE THE FOLLOWING ELEMENTS: - INDEPENDENT BODY - COMMITTEE MEMBERS COMPLETE AN ANNUAL CONFLICT OF INTEREST SURVEY TO ASSURE THE COMMITTEE MEMBERS' INDEPENDENCE - STAFF IS NOT IN ROOM DURING DELIBERATIONS OR VOTE INCLUDING EXECUTIVE SESSIONS - AUTHORIZED BODY - BOARD OF DIRECTORS HAS DELEGATED TO THE COMPENSATION COMMITTEE THE ACCOUNTABILITY AND AUTHORITY TO REVIEW AND APPROVE THE COMPARABILITY DATA OF ALL OFFICERS AND MEDICAL DIRECTORS - THE BOARD OF DIRECTORS HAS DELEGATED TO THE COMPENSATION COMMITTEE THE ACCOUNTABILITY TO CONDUCT AN ANNUAL PERFORMANCE EVALUATION AND TO DETERMINE THE COMPENSATION OF THE EXECUTIVE DIRECTOR AND OTHER OFFICERS BASED ON THE PERFORMANCE REVIEW AND THE MARKET COMPARABILITY DATA - COMPARABILITY DATA - EVERY THREE YEARS, THE COMPENSATION COMMITTEE RETAINS AN INDEPENDENT COMPENSATION EXPERT TO CONDUCT AN EXTENSIVE MARKET COMPARABILITY SURVEY FOR ALL OFFICERS OF THE ORGANIZATION AS WELL AS ITS MDS. WITH THE INPUT OF THE CONSULTANT, THE COMPENSATION COMMITTEE DETERMINED APPROPRIATE PEER GROUPS INCLUDING BOTH LOCAL AND NATIONAL PEER GROUPS. THE SURVEY CONSIDERS EACH ELEMENT OF TOTAL COMPENSATION AND AGGREGATE TOTAL COMPENSATION. BASED ON THIS DATA, THE COMPENSATION COMMITTEE DETERMINES MINIMUM AND MAXIMUM TOTAL COMPENSATION RANGES FOR EACH OFFICER OR MD. IN INTERIM YEARS, GHI'S HUMAN RESOURCE DEPARTMENT, UNDER THE COMPENSATION COMMITTEE'S DIRECTION USES THE SAME RECOGNIZED THIRD PARTY SALARY SURVEYS TO DETERMINE MEDIAN SALARY STRUCTURE CHANGES AND AVERAGE SALARY INCREASES. BASED ON THIS UPDATED DATA, THE COMPENSATION COMMITTEE DETERMINES THE TOTAL COMPENSATION RANGES FOR EACH OFFICER OR MEDICAL DIRECTOR. - THE ELEMENTS OF TOTAL COMPENSATION ARE SALARY, INCENTIVES, BENEFITS AND PERQUISITES. - PROPER CONTEMPORANEOUS DOCUMENTATION - MINUTES OF THE COMPENSATION COMMITTEE ARE PREPARED AFTER EACH MEETING AND APPROVED AT THE NEXT MEETING. - TOTAL COMPENSATION IS APPROPRIATELY REPORTED ON THE FORM 990 AND ON THE EMPLOYEE'S W-2. FORM 990, PART VI, SECTION C, LINE 19 HPRF'S FINANCIAL STATEMENTS AND 990 RETURNS ARE MADE AVAILABLE TO ANY PERSON WHO REQUESTS THE INFORMATION FROM HPRF OR HEALTHPARTNERS, INC. HPRF'S ARTICLES OF INCORPORATION ARE AVAILABLE TO ANY PERSON WHO REQUESTS THE INFORMATION THROUGH THE MINNESOTA SECRETARY OF STATE'S OFFICE. HPRF'S CONFLICT OF INTEREST POLICY WHICH IS THE SAME AS THAT OF IT'S RELATED ORGANIZATIONS, HEALTHPARTNERS, INC. AND GROUP HEALTH PLAN, INC. CAN BE VIEWED THROUGH THE HEALTHPARTNERS.COM WEBSITE. AVERAGE HOURS PER WEEK - RELATED ORGANIZATION FORM 990, PART VII, SECTION A, LINE 1A, COLUMN (B) ALL OFFICERS OF HPRF ARE EMPLOYED AND COMPENSATED BY GHI. THE REPORTED AVERAGE HOURS WORKED ARE BASED ON THEIR TOTAL COMPENSATION FROM ALL RELATED ORGANIZATIONS. CHANGES IN NET ASSETS OR FUND BALANCES: FORM 990, PART XI, LINE 5: FASB 136 - BENEFICIAL INTEREST IN NET ASSETS OF REGIONS HOSPITAL FOUNDATION -1,271,429. FASB 124 - FAIR MARKET VALUATION ADJUSTMENT -340,737. TOTAL TO FORM 990, PART XI, LINE 5: -1,612,166. GROUP HEALTH PLAN INC 8170 33RD AVENUE SOUTH PO BOX 1309 MINNEAPOLIS MN 554401309 410797853 STAFF MODEL HEALTH MAINTENANCE ORGANIZATION MN 501(C)(3) 170(B)(1) (A)(III) HEALTHPARTNERS INC 0 REGIONS HOSPITAL 8170 33RD AVENUE SOUTH PO BOX 1309 MINNEAPOLIS MN 554401309 410956618 HOSPITAL MN 501(C)(3) 170(B)(1) (A)(III) HPI - RAMSEY 0 HEALTHPARTNERS INC 8170 33RD AVENUE SOUTH PO BOX 1309 MINNEAPOLIS MN 554401309 411693838 HYBRID STAFF MODEL/NETWORK MODEL HEALTH MAINTENANCE ORGANIZATION MN 501(C)(4) N/A 0 HEALTHPARTNERS CENTRAL MINNESOTA CLINICS INC 8170 33RD AVE S PO BOX 1309 MPLS MN 554401309 411236798 PRIMARY AND SPECIALTY PATIENT CARE MN 501(C)(3) 170(B)(1) (A)(III) GROUP HEALTH PLAN INC 0 HPI - RAMSEY 8170 33RD AVENUE SOUTH PO BOX 1309 MINNEAPOLIS MN 554401309 411793333 CORPORATE PLANNING AND OVERSIGHT MN 501(C)(3) 509(A)(3) TYPE I HEALTHPARTNERS INC 0 HEALTHPARTNERS INSTITUTE FOR MEDICAL EDUCATION 8170 33RD AVE S PO BOX 1309 MPLS MN 554401309 411835843 MEDICAL EDUCATION MN 501(C)(3) 509(A)(3) TYPE I HEALTHPARTNERS INC 0 CAPITAL VIEW TRANSITIONAL CARE CENTER 8170 33RD AVENUE SOUTH PO BOX 1309 MINNEAPOLIS MN 554401309 412011453 POST HOSPITALIZATION PATIENT CARE MN 501(C)(3) 170(B)(1) (A)(III) HPI - RAMSEY 0 RAMSEY INTEGRATED HEALTH SERVICES 8170 33RD AVENUE SOUTH PO BOX 1309 MINNEAPOLIS MN 554401309 411503090 IN HOME PATIENT CARE MN 501(C)(3) 509(A)(2) HPI - RAMSEY 0 REGIONS HOSPITAL FOUNDATION 8170 33RD AVENUE SOUTH PO BOX 1309 MINNEAPOLIS MN 554401309 411888902 PROVIDE HOSPITAL PROGRAM FINANCIAL SUPPORT MN 501(C)(3) 170(B)(1) (A)(VI) HPI - RAMSEY 0 RHSC INC 8170 33RD AVENUE SOUTH PO BOX 1309 MINNEAPOLIS MN 554401309 411891928 HEALTHCARE STAFFING MN 501(C)(3) 509(A)(3) TYPE II HEALTHPARTNERS INC 0 WESTFIELDS HOSPITAL INC 8170 33RD AVENUE SOUTH PO BOX 1309 MINNEAPOLIS MN 554401309 390808442 HOSPITAL WI 501(C)(3) 170(B)(1) (A)(III) RH-WISCONSIN 0 WESTFIELDS HOSPITAL FOUNDATION INC 8170 33RD AVENUE SOUTH PO BOX 1309 MINNEAPOLIS MN 554401309 391770913 PROVIDE HOSPITAL PROGRAM FINANCIAL SUPPORT WI 501(C)(3) 509(A)(3) TYPE I WESTFIELDS HOSPITAL INC 0 RH-WISCONSIN 8170 33RD AVENUE SOUTH PO BOX 1309 MINNEAPOLIS MN 554401309 202287016 CORPORATE PLANNING AND OVERSIGHT WI 501(C)(3) 509(A)(3) TYPE II HPI - RAMSEY 0 PHYSICIANS NECK AND BACK CLINICS 8170 33RD AVENUE SOUTH PO BOX 1309 MINNEAPOLIS MN 554401309 270684883 SPECIALTY PATIENT CARE MN 501(C)(3) 509(A)(3) TYPE II GROUP HEALTH PLAN INC 0 HUDSON HOSPITAL INC 8170 33RD AVENUE SOUTH PO BOX 1309 MINNEAPOLIS MN 554401309 390804125 HOSPITAL WI 501(C)(3) 170(B)(1) (A)(III) RH-WISCONSIN 0 HUDSON HOSPITAL FOUNDATION INC 8170 33RD AVENUE SOUTH PO BOX 1309 MINNEAPOLIS MN 554401309 391279567 PROVIDE HOSPITAL PROGRAM FINANCIAL SUPPORT WI 501(C)(3) 170(B)(1) (A)(VI) HUDSON HOSPITAL INC 0 WESTERN WISCONSIN EMERGENCY MEDICAL SERVICES COMPANY 8170 33RD AVE S PO BOX 1309 MPLS MN 554401309 263616590 PROVIDE MEDICAL TRANSPORT SERVICES WI 501(C)(3) 509(A)(3) TYPE II RH-WISCONSIN 0 LAKEVIEW MEMORIAL HOSPITAL FOUNDATION 8170 33RD AVE S PO BOX 1309 MPLS MN 554401309 411386635 PROVIDE HOSPITAL PROGRAM FINANCIAL SUPPORT MN 501(C)(3) 509(A)(3) TYPE II STILLWATER HEALTH SYSTEM 0 LAKEVIEW MEMORIAL HOSPITAL ASSOCIATION INC 8170 33RD AVE S PO BOX 1309 MPLS MN 554401309 410811697 HOSPITAL MN 501(C)(3) 170(B)(1) (A)(III) STILLWATER HEALTH SYSTEM 0 ST CROIX VALLEY HEALTHCARE & RESEARCH FOUNDATION 8170 33RD AVE S PO BOX 1309 MPLS MN 554401309 411923524 FOUNDATION MN 501(C)(3) PF STILLWATER HEALTH SYSTEM 0 STILLWATER MEDICAL GROUP 8170 33RD AVE S PO BOX 1309 MPLS MN 554401309 830379473 PHYSICIANS GROUP MN 501(C)(3) 509(A)(2) STILLWATER HEALTH SYSTEM 0 STILLWATER HEALTH SYSTEM 8170 33RD AVE S PO BOX 1309 MPLS MN 554401309 300221189 CORPORATE PLANNING AND OVERSIGHT MN 501(C)(3) 509(A)(3) TYPE II HPI - RAMSEY 0 HEALTHPARTNERS ADMINISTRATORS INC 8170 33RD AVENUE SOUTH PO BOX 1309 MINNEAPOLIS MN 554401309 411629390 THIRD PARTY ADMINISTRATOR MN HEALTHPARTNERS INC C HEALTHPARTNERS ASSOCIATES INC 8170 33RD AVENUE SOUTH PO BOX 1309 MINNEAPOLIS MN 554401309 522365151 MEDICAL CLINIC STAFFING AND ASSET MANAGEMENT MN HEALTHPARTNERS ADMINISTRATORS INC C HEALTHPARTNERS SERVICES INC 8170 33RD AVENUE SOUTH PO BOX 1309 MINNEAPOLIS MN 554401309 411683568 MEDICAL CLINIC STAFFING AND ASSET MANAGEMENT MN HEALTHPARTNERS ADMINISTRATORS INC C HEALTHPARTNERS VENTURES INC 8170 33RD AVENUE SOUTH PO BOX 1309 MINNEAPOLIS MN 554401309 411838197 DEVELOP HEALTHCARE BUSINESS OPPORTUNITIES MN HEALTHPARTNERS INC C HEALTHPARTNERS INSURANCE COMPANY 8170 33RD AVENUE SOUTH PO BOX 1309 MINNEAPOLIS MN 554401309 411683523 MEDICAL AND DENTAL INSURANCE MN HEALTHPARTNERS ADMINISTRATORS INC C DENTAL SPECIALTIES INC 8170 33RD AVENUE SOUTH PO BOX 1309 MINNEAPOLIS MN 554401309 451297583 PROFESSIONAL DENTAL SERVICES MN HEALTHPARTNERS ADMINISTRATORS INC C 0 0 0 0 0 0 0 0 0 0 0 0 0 1 1 1 0 0