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        <Explanation>SCHEDULE F, PART I, LINE 2: THE ORGANIZATION REQUIRES THAT ANY USE OF GRANT FUNDS BE REVIEWED BY THE CFO AND THE PRESIDENT TO ENSURE THAT SUCH GRANTS ARE USED FOR PROPER PURPOSES AND ARE NOT OTHERWISE DIVERTED FROM THEIR INTENDED USE.</Explanation>
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        <GrossReceiptsTotal>106875</GrossReceiptsTotal>
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        <OtherDirectExpensesTotalEvents>48530</OtherDirectExpensesTotalEvents>
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        <NetIncomeSummary>-55712</NetIncomeSummary>
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        </RecipientNameBusiness>
        <AddressUS>
          <AddressLine1>759 CHESTNUT STREET</AddressLine1>
          <City>SPRINGFIELD</City>
          <State>MA</State>
          <ZIPCode>01199</ZIPCode>
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        <EINOfRecipient>042790311</EINOfRecipient>
        <IRCSection>501(C)(3)</IRCSection>
        <AmountOfCashGrant>38000</AmountOfCashGrant>
        <PurposeOfGrant>MEDICAL RESEARCH</PurposeOfGrant>
      </RecipientTable>
      <RecipientTable>
        <RecipientNameBusiness>
          <BusinessNameLine1>CALIFORNIA PACIFIC MEDICAL CENTER</BusinessNameLine1>
        </RecipientNameBusiness>
        <AddressUS>
          <AddressLine1>2351 CLAY STREET SUITE 134</AddressLine1>
          <City>SAN FRANCISCO</City>
          <State>CA</State>
          <ZIPCode>94115</ZIPCode>
        </AddressUS>
        <EINOfRecipient>940562680</EINOfRecipient>
        <IRCSection>501(C)(3)</IRCSection>
        <AmountOfCashGrant>1500</AmountOfCashGrant>
        <PurposeOfGrant>MEDICAL RESEARCH</PurposeOfGrant>
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      <RecipientTable>
        <RecipientNameBusiness>
          <BusinessNameLine1>MAYO CLINIC JACKSONVILLE</BusinessNameLine1>
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        <AddressUS>
          <AddressLine1>4500 SAN PABLO ROAD</AddressLine1>
          <City>JACKSONVILLE</City>
          <State>FL</State>
          <ZIPCode>32224</ZIPCode>
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        <EINOfRecipient>416011702</EINOfRecipient>
        <IRCSection>501(C)(3)</IRCSection>
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        <PurposeOfGrant>MEDICAL RESEARCH</PurposeOfGrant>
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      <RecipientTable>
        <RecipientNameBusiness>
          <BusinessNameLine1>REGENTS OF THE UNIVERSITY OF CALIFORNIA</BusinessNameLine1>
        </RecipientNameBusiness>
        <AddressUS>
          <AddressLine1>9500 GILMAN DRIVE</AddressLine1>
          <City>LA JOLLA</City>
          <State>CA</State>
          <ZIPCode>92093</ZIPCode>
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        <EINOfRecipient>956006144</EINOfRecipient>
        <IRCSection>501(C)(3)</IRCSection>
        <AmountOfCashGrant>20000</AmountOfCashGrant>
        <PurposeOfGrant>MEDICAL RESEARCH</PurposeOfGrant>
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      <RecipientTable>
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          <BusinessNameLine1>REGENTS OF THE UNIVERSITY OF MICHIGAN</BusinessNameLine1>
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          <AddressLine1>RM 1054 WOLVERINE TOWER SPC 1274</AddressLine1>
          <AddressLine2>3003 S STATE</AddressLine2>
          <City>ANN ARBOR</City>
          <State>MI</State>
          <ZIPCode>48109</ZIPCode>
        </AddressUS>
        <EINOfRecipient>386006309</EINOfRecipient>
        <IRCSection>501(C)(3)</IRCSection>
        <AmountOfCashGrant>195000</AmountOfCashGrant>
        <PurposeOfGrant>MEDICAL RESEARCH</PurposeOfGrant>
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      <RecipientTable>
        <RecipientNameBusiness>
          <BusinessNameLine1>TEMPLE UNIVESRITY OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION</BusinessNameLine1>
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        <AddressUS>
          <AddressLine1>3400 N BROAD STREET RM 427G</AddressLine1>
          <City>PHILADELPHIA</City>
          <State>PA</State>
          <ZIPCode>19140</ZIPCode>
        </AddressUS>
        <EINOfRecipient>231365971</EINOfRecipient>
        <IRCSection>501(C)(3)</IRCSection>
        <AmountOfCashGrant>75000</AmountOfCashGrant>
        <PurposeOfGrant>MEDICAL RESEARCH</PurposeOfGrant>
      </RecipientTable>
      <RecipientTable>
        <RecipientNameBusiness>
          <BusinessNameLine1>THE UNIVERSITY OF NORTH CAROLINA</BusinessNameLine1>
        </RecipientNameBusiness>
        <AddressUS>
          <AddressLine1>104 AIRPORT DRIVE CB1350</AddressLine1>
          <City>CHAPEL HILLS</City>
          <State>NC</State>
          <ZIPCode>27599</ZIPCode>
        </AddressUS>
        <EINOfRecipient>566001393</EINOfRecipient>
        <IRCSection>501(C)(3)</IRCSection>
        <AmountOfCashGrant>150000</AmountOfCashGrant>
        <PurposeOfGrant>MEDICAL RESEARCH</PurposeOfGrant>
      </RecipientTable>
      <RecipientTable>
        <RecipientNameBusiness>
          <BusinessNameLine1>TRUSTEES OF INDIANA UNIVERSITY</BusinessNameLine1>
        </RecipientNameBusiness>
        <AddressUS>
          <AddressLine1>PO BOX 66057</AddressLine1>
          <City>INDIANAPOLIS</City>
          <State>IN</State>
          <ZIPCode>46266</ZIPCode>
        </AddressUS>
        <EINOfRecipient>356001673</EINOfRecipient>
        <IRCSection>501(C)(3)</IRCSection>
        <AmountOfCashGrant>50000</AmountOfCashGrant>
        <PurposeOfGrant>MEDICAL RESEARCH</PurposeOfGrant>
      </RecipientTable>
      <RecipientTable>
        <RecipientNameBusiness>
          <BusinessNameLine1>YALE UNIVERSITY SCHOOL OF MEDICINE</BusinessNameLine1>
        </RecipientNameBusiness>
        <AddressUS>
          <AddressLine1>PO BOX 208087</AddressLine1>
          <City>NEW HAVEN</City>
          <State>CT</State>
          <ZIPCode>06520</ZIPCode>
        </AddressUS>
        <EINOfRecipient>060646973</EINOfRecipient>
        <IRCSection>501(C)(3)</IRCSection>
        <AmountOfCashGrant>38000</AmountOfCashGrant>
        <PurposeOfGrant>MEDICAL RESEARCH</PurposeOfGrant>
      </RecipientTable>
      <TotalNbrOf501C3AndGovtGrants>9</TotalNbrOf501C3AndGovtGrants>
      <TotalNbrOfOtherOrganizations>0</TotalNbrOfOtherOrganizations>
      <Form990ScheduleIPartIII>
        <TypeOfGrant>MEDICAL RESEARCH</TypeOfGrant>
        <NumberOfRecipients>8</NumberOfRecipients>
        <AmountOfCashGrant>28500</AmountOfCashGrant>
        <AmountOfNonCashAssistance>0</AmountOfNonCashAssistance>
      </Form990ScheduleIPartIII>
      <Form990ScheduleIPartIV>
        <Identifier>PROCEDURE FOR MONITORING GRANTS IN THE U.S.:</Identifier>
        <ReturnReference>PART I, LINE 2:</ReturnReference>
        <Explanation>SCHEDULE I, PART I, LINE 2: THE ORGANIZATION REQUIRES THAT ANY USE OF GRANT FUNDS BE REVIEWED BY THE CFO AND THE PRESIDENT TO ENSURE THAT SUCH GRANTS ARE USED FOR PROPER PURPOSES AND ARE NOT OTHERWISE DIVERTED FROM THEIR INTENDED USE.</Explanation>
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    <IRS990ScheduleJ documentId="RetDoc1042400001">
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      <WrittenEmploymentContract>X</WrittenEmploymentContract>
      <CompensationSurvey>X</CompensationSurvey>
      <BoardOrCommitteeApproval>X</BoardOrCommitteeApproval>
      <SeverancePayment>0</SeverancePayment>
      <SupplementalNonqualRetirePlan>0</SupplementalNonqualRetirePlan>
      <EquityBasedCompArrangement>0</EquityBasedCompArrangement>
      <CompBasedOnRevenueOfFilingOrg>0</CompBasedOnRevenueOfFilingOrg>
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      <AnyNonFixedPayments>0</AnyNonFixedPayments>
      <InitialContractException>0</InitialContractException>
      <Form990ScheduleJPartII>
        <NamePerson>PATRICIA BLAKE</NamePerson>
        <BaseCompensationFilingOrg>251079</BaseCompensationFilingOrg>
        <CompBasedOnRelatedOrgs>0</CompBasedOnRelatedOrgs>
        <BonusFilingOrg>0</BonusFilingOrg>
        <BonusRelatedOrgs>0</BonusRelatedOrgs>
        <OtherCompensationFilingOrg>0</OtherCompensationFilingOrg>
        <OtherCompensationRelatedOrgs>0</OtherCompensationRelatedOrgs>
        <DeferredCompFilingOrg>17350</DeferredCompFilingOrg>
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        <NontaxableBenefitsFilingOrg>22620</NontaxableBenefitsFilingOrg>
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        <TotalCompensationRelatedOrgs>0</TotalCompensationRelatedOrgs>
        <CompReportPrior990FilingOrg>0</CompReportPrior990FilingOrg>
        <CompReportPrior990RelatedOrgs>0</CompReportPrior990RelatedOrgs>
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      <Form990ScheduleJPartII>
        <NamePerson>SAMUEL HAROZ</NamePerson>
        <BaseCompensationFilingOrg>150812</BaseCompensationFilingOrg>
        <CompBasedOnRelatedOrgs>0</CompBasedOnRelatedOrgs>
        <BonusFilingOrg>0</BonusFilingOrg>
        <BonusRelatedOrgs>0</BonusRelatedOrgs>
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        <OtherCompensationRelatedOrgs>0</OtherCompensationRelatedOrgs>
        <DeferredCompFilingOrg>4524</DeferredCompFilingOrg>
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        <NontaxableBenefitsFilingOrg>13457</NontaxableBenefitsFilingOrg>
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        <TotalCompensationRelatedOrgs>0</TotalCompensationRelatedOrgs>
        <CompReportPrior990FilingOrg>0</CompReportPrior990FilingOrg>
        <CompReportPrior990RelatedOrgs>0</CompReportPrior990RelatedOrgs>
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      <Form990ScheduleJPartII>
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        <TotalCompensationRelatedOrgs>0</TotalCompensationRelatedOrgs>
        <CompReportPrior990FilingOrg>0</CompReportPrior990FilingOrg>
        <CompReportPrior990RelatedOrgs>0</CompReportPrior990RelatedOrgs>
      </Form990ScheduleJPartII>
      <Form990ScheduleJPartII>
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        <CompBasedOnRelatedOrgs>0</CompBasedOnRelatedOrgs>
        <BonusFilingOrg>0</BonusFilingOrg>
        <BonusRelatedOrgs>0</BonusRelatedOrgs>
        <OtherCompensationFilingOrg>0</OtherCompensationFilingOrg>
        <OtherCompensationRelatedOrgs>0</OtherCompensationRelatedOrgs>
        <DeferredCompFilingOrg>4097</DeferredCompFilingOrg>
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        <NontaxableBenefitsRelatedOrgs>0</NontaxableBenefitsRelatedOrgs>
        <TotalCompensationFilingOrg>153472</TotalCompensationFilingOrg>
        <TotalCompensationRelatedOrgs>0</TotalCompensationRelatedOrgs>
        <CompReportPrior990FilingOrg>0</CompReportPrior990FilingOrg>
        <CompReportPrior990RelatedOrgs>0</CompReportPrior990RelatedOrgs>
      </Form990ScheduleJPartII>
      <Form990ScheduleJPartII>
        <NamePerson>LARRY ROBERTSON</NamePerson>
        <BaseCompensationFilingOrg>130406</BaseCompensationFilingOrg>
        <CompBasedOnRelatedOrgs>0</CompBasedOnRelatedOrgs>
        <BonusFilingOrg>0</BonusFilingOrg>
        <BonusRelatedOrgs>0</BonusRelatedOrgs>
        <OtherCompensationFilingOrg>0</OtherCompensationFilingOrg>
        <OtherCompensationRelatedOrgs>0</OtherCompensationRelatedOrgs>
        <DeferredCompFilingOrg>3912</DeferredCompFilingOrg>
        <DeferredCompRelatedOrgs>0</DeferredCompRelatedOrgs>
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        <NontaxableBenefitsRelatedOrgs>0</NontaxableBenefitsRelatedOrgs>
        <TotalCompensationFilingOrg>154174</TotalCompensationFilingOrg>
        <TotalCompensationRelatedOrgs>0</TotalCompensationRelatedOrgs>
        <CompReportPrior990FilingOrg>0</CompReportPrior990FilingOrg>
        <CompReportPrior990RelatedOrgs>0</CompReportPrior990RelatedOrgs>
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    </IRS990ScheduleJ>
    <IRS990ScheduleM documentId="RetDoc1042900001">
      <OtherNonCashContributionsTable>
        <NonCashCheckbox>X</NonCashCheckbox>
        <Description>EQUIPMENT RENTAL</Description>
        <NumberOfContributions>3</NumberOfContributions>
        <NoncashContribsRptdF990>315211</NoncashContribsRptdF990>
        <MethodOfDeterminingRevenues>FAIR MARKET VALUE</MethodOfDeterminingRevenues>
      </OtherNonCashContributionsTable>
      <OtherNonCashContributionsTable>
        <NonCashCheckbox>X</NonCashCheckbox>
        <Description>HONORAIRIA</Description>
        <NumberOfContributions>8</NumberOfContributions>
        <NoncashContribsRptdF990>66345</NoncashContribsRptdF990>
        <MethodOfDeterminingRevenues>FAIR MARKET VALUE</MethodOfDeterminingRevenues>
      </OtherNonCashContributionsTable>
      <AnyPropertyThatMustBeHeld>0</AnyPropertyThatMustBeHeld>
      <ReviewProcessUnusualNCGifts>1</ReviewProcessUnusualNCGifts>
      <ThirdPartiesUsed>0</ThirdPartiesUsed>
    </IRS990ScheduleM>
    <IRS990ScheduleO documentId="RetDoc1044400001">
      <GeneralExplanation>
        <ReturnReference>FORM 990, PART VI, SECTION A, LINE 6</ReturnReference>
        <Explanation>THE SOCIETY SHALL HAVE EIGHT CLASSES OF MEMBERSHIP: ACTIVE, FELLOW, SENIOR, HONORARY, INTERNATIONAL, TRAINEE, ASSOCIATE AND AFFILIATE.</Explanation>
      </GeneralExplanation>
      <GeneralExplanation>
        <ReturnReference>FORM 990, PART VI, SECTION A, LINE 7A</ReturnReference>
        <Explanation>ONLY ACTIVE MEMBERS IN ATTENDANCE AT THE ANNUAL MEETING MAY ELECT ONE OR MORE MEMBERS OF THE GOVERNING BODY OF THE SOCIETY.</Explanation>
      </GeneralExplanation>
      <GeneralExplanation>
        <ReturnReference>FORM 990, PART VI, SECTION A, LINE 7B</ReturnReference>
        <Explanation>ONLY ACTIVE MEMBERS IN ATTENDANCE AT THE ANNUAL MEETING VOTE ON DECISIONS OF THE GOVERNING BODY OF THE SOCIETY THAT ARE SUBJECT TO THE APPROVAL OF THE MEMBERSHIP. THESE DECISIONS INCLUDE CHANGES TO THE BYLAWS.</Explanation>
      </GeneralExplanation>
      <GeneralExplanation>
        <ReturnReference>FORM 990, PART VI, SECTION B, LINE 11</ReturnReference>
        <Explanation>FORM 990 IS REVIEWED BY THE AUDIT COMMITTEE, THE EXECUTIVE DIRECTOR AND THE DIRECTOR OF FINANCE, AND OTHER MEMBERS OF THE BOARD.</Explanation>
      </GeneralExplanation>
      <GeneralExplanation>
        <ReturnReference>FORM 990, PART VI, SECTION B, LINE 12C</ReturnReference>
        <Explanation>THE MEMBER-DOCTORS IN LEADERSHIP POSITIONS ARE REQUIRED TO PROVIDE WRITTEN DOCUMENTATION TO DISCLOSE ANY CONFLICTS OF INTEREST. THIS PROCESS OCCURS ON AN ANNUAL BASIS.</Explanation>
      </GeneralExplanation>
      <GeneralExplanation>
        <ReturnReference>FORM 990, PART VI, SECTION B, LINE 15</ReturnReference>
        <Explanation>COMPENSATION FOR ALL OFFICERS, DIRECTORS, AND KEY EMPLOYEES IS DETERMINED BY THE COMPENSATION COMMITTEE, WHICH IS COMPRISED OF MEMBERS OF THE BOARD OF DIRECTORS. THE DETERMINATION OF COMPENSATION IS BASED ON A COMPARABILITY STUDY THAT IS PREPARED EVERY OTHER YEAR BY AN OUTSIDE HUMAN RESOURCES FIRM. THE SENIOR DIRECTOR OF HUMAN RESOURCES DOCUMENTS ALL INFORMATION AND DELIBERATION REGARDING DETERMINATION OF COMPENSATION. EMPLOYEES HAVE A FORMAL ANNUAL REVIEW OF PERFORMANCE BY THEIR MANAGER. ALL STAFF SALARIES ARE APPROVED BY THE EXECUTIVE DIRECTOR.</Explanation>
      </GeneralExplanation>
      <GeneralExplanation>
        <ReturnReference>FORM 990, PART VI, SECTION C, LINE 19</ReturnReference>
        <Explanation>DOCUMENTS PUBLISHED ON THE ORGANIZATION'S WEBSITE STATE THAT THE ORGANIZATION'S GOVERNING DOCUMENTS, CONFLICT OF INTEREST POLICY, AND FINANCIAL STATEMENTS ARE AVAILABLE UPON REQUEST.</Explanation>
      </GeneralExplanation>
      <GeneralExplanation>
        <Identifier>CHANGES IN NET ASSETS OR FUND BALANCES:</Identifier>
        <ReturnReference>FORM 990, PART XI, LINE 5:</ReturnReference>
        <Explanation>NET UNREALIZED LOSSES ON INVESTMENTS: -1,535,224.</Explanation>
      </GeneralExplanation>
      <GeneralExplanation>
        <ReturnReference>FORM 990, PART XII, LINE 2C</ReturnReference>
        <Explanation>THE PROCESS FOR OVERSIGHT OF THE AUDIT AND THE SELECTION OF AN INDEPENDENT ACCOUNTANT HAS NOT CHANGED FROM THE PRIOR YEAR.</Explanation>
      </GeneralExplanation>
    </IRS990ScheduleO>
    <IRS990ScheduleR documentId="RetDoc1043400001">
      <Form990ScheduleRPartI>
        <NameOfDisregardedEntity>
          <BusinessNameLine1>DIGESTIVE HEALTHWORKS LLC</BusinessNameLine1>
        </NameOfDisregardedEntity>
        <AddressUS>
          <AddressLine1>1520 KENSINGTON ROAD SUITE 202</AddressLine1>
          <City>OAK BROOK</City>
          <State>IL</State>
          <ZIPCode>60523</ZIPCode>
        </AddressUS>
        <EIN>371595036</EIN>
        <PrimaryActivities>MANAGEMENT SERVICES</PrimaryActivities>
        <LegalDomicileState>IL</LegalDomicileState>
        <TotalIncome>118746</TotalIncome>
        <EOYAssets>68163</EOYAssets>
        <DirectControllingEntityName>
          <BusinessNameLine1>ASGE</BusinessNameLine1>
        </DirectControllingEntityName>
      </Form990ScheduleRPartI>
    </IRS990ScheduleR>
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