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        <DescriptionOfTransaction>spouse of lauren Rachlin, Board member and Senior Program Analyst for frontier. Jean is an employee at Frontier.</DescriptionOfTransaction>
        <SharingOfRevenues>0</SharingOfRevenues>
      </Form990ScheduleLPartIV>
      <Form990ScheduleLPartIV>
        <NameOfInterestedPerson>
          <NamePerson>lauren rachlin</NamePerson>
        </NameOfInterestedPerson>
        <Relationship>BOD member</Relationship>
        <AmountOfTransaction>198173</AmountOfTransaction>
        <DescriptionOfTransaction>Lauren rachlin is a BOD member of FSTRF and also a Partner of the law firm that provides legal services to FSTRF.</DescriptionOfTransaction>
        <SharingOfRevenues>0</SharingOfRevenues>
      </Form990ScheduleLPartIV>
    </IRS990ScheduleL>
    <IRS990ScheduleO documentId="RetDoc1044400001">
      <GeneralExplanation>
        <Identifier>Form 990, Part VI, Section A, line 2</Identifier>
        <Explanation>Thelma Zelen, Chief Administrative Officer is the wife of Marvin Zelen, Chairman and President. The wife of Richard Gelber, Treasurer of the Board, is employed at FSTRF. The wife of Lauren Rachlin, Board Member, is employed at FSTRF (See Schedule L for further disclosures).</Explanation>
      </GeneralExplanation>
      <GeneralExplanation>
        <Identifier>Form 990, Part VI, Section B, line 11</Identifier>
        <Explanation>A copy of the 990 is emailed to the Board for review. A subsequent meeting is held to go over any questions or comments and then it is approved by vote.</Explanation>
      </GeneralExplanation>
      <GeneralExplanation>
        <Identifier>Form 990, Part VI, Section B, line 12c</Identifier>
        <Explanation>On a case by case basis, management will follow up on making sure all conflicts of interest are disclosed.</Explanation>
      </GeneralExplanation>
      <GeneralExplanation>
        <Identifier>Form 990, Part VI, Section B, line 15</Identifier>
        <Explanation>Frontier has a separate Compensation Committee that determines market rates for the Directors and officers and annual reviews/increases for these individuals are set &amp; approved by this Committee. The Compensation Committee is made up of three Frontier Board members who are not also employees of Frontier Lauren Rachlin, Thomas Habermann, and Lee-Jen Wei.</Explanation>
      </GeneralExplanation>
      <GeneralExplanation>
        <Identifier>Form 990, Part VI, Section C, line 19</Identifier>
        <Explanation>Upon request.</Explanation>
      </GeneralExplanation>
      <GeneralExplanation>
        <Identifier>Form 990, Part XI, line 2c:</Identifier>
        <Explanation>There was no change to the oversight process.</Explanation>
      </GeneralExplanation>
    </IRS990ScheduleO>
    <IRS990ScheduleR documentId="RetDoc1043400001">
      <Form990ScheduleRPartII>
        <NameOfDisregardedEntity>
          <BusinessNameLine1>FRONTIER SCIENCE (SCOTLAND) Ltd</BusinessNameLine1>
        </NameOfDisregardedEntity>
        <AddressForeign>
          <AddressLine1>grampian view PH21 1NA</AddressLine1>
          <City>kincraig inverness-shire</City>
          <Country>UK</Country>
        </AddressForeign>
        <PrimaryActivities>education of clincial trials and statistical science</PrimaryActivities>
        <LegalDomicileForeignCountry>UK</LegalDomicileForeignCountry>
        <ExemptCodeSection>13(1)</ExemptCodeSection>
        <DirectControllingEntityNA>N/A</DirectControllingEntityNA>
      </Form990ScheduleRPartII>
      <Form990ScheduleRPartII>
        <NameOfDisregardedEntity>
          <BusinessNameLine1>FRONTIER SCIENCE FOUNDATION - HELLAS</BusinessNameLine1>
        </NameOfDisregardedEntity>
        <AddressForeign>
          <AddressLine1>mikras asias 70 11527 goudi</AddressLine1>
          <City>athens</City>
          <Country>GR</Country>
        </AddressForeign>
        <EIN>118050334</EIN>
        <PrimaryActivities>research in bio statistics and health sciences</PrimaryActivities>
        <LegalDomicileForeignCountry>GR</LegalDomicileForeignCountry>
        <DirectControllingEntityNA>N/A</DirectControllingEntityNA>
      </Form990ScheduleRPartII>
      <Form990ScheduleRPartIV>
        <NameOfRelatedOrg>
          <BusinessNameLine1>Frontier Science Associates Inc</BusinessNameLine1>
        </NameOfRelatedOrg>
        <AddressUS>
          <AddressLine1>4033 Maple Road</AddressLine1>
          <City>Amherst</City>
          <State>NY</State>
          <ZIPCode>14226</ZIPCode>
        </AddressUS>
        <EIN>161479978</EIN>
        <PrimaryActivity>To assist FSTRF in performing research projects involving</PrimaryActivity>
        <LegalDomicileState>NY</LegalDomicileState>
        <DirectControllingEntityNA>N/A</DirectControllingEntityNA>
        <TypeOfEntity>C</TypeOfEntity>
        <ShareOfEOYAssets>9687</ShareOfEOYAssets>
        <PercentageOwnership>1.00000</PercentageOwnership>
      </Form990ScheduleRPartIV>
      <ReceiptOfIntAnnRentsRoyalties>0</ReceiptOfIntAnnRentsRoyalties>
      <GiftGrantOrCapContrToOtherOrg>0</GiftGrantOrCapContrToOtherOrg>
      <GiftGrantOrCapContrFrOtherOrg>0</GiftGrantOrCapContrFrOtherOrg>
      <LoansOrGuaranteesToOtherOrg>1</LoansOrGuaranteesToOtherOrg>
      <LoansOrGuaranteesFromOtherOrg>0</LoansOrGuaranteesFromOtherOrg>
      <SaleOfAssetsToOtherOrg>0</SaleOfAssetsToOtherOrg>
      <PurchaseOfAssetsFromOtherOrg>0</PurchaseOfAssetsFromOtherOrg>
      <ExchangeOfAssets>0</ExchangeOfAssets>
      <RentalOfFacilitiesToOtherOrgs>0</RentalOfFacilitiesToOtherOrgs>
      <RentalOfFacilitiesFrOtherOrgs>0</RentalOfFacilitiesFrOtherOrgs>
      <PerformOfServicesForOtherOrgs>0</PerformOfServicesForOtherOrgs>
      <PerformOfServicesByOtherOrgs>0</PerformOfServicesByOtherOrgs>
      <SharingOfFacilities>0</SharingOfFacilities>
      <SharingOfPaidEmployees>0</SharingOfPaidEmployees>
      <ReimbursementPaidToOtherOrg>0</ReimbursementPaidToOtherOrg>
      <ReimbursementPaidByOtherOrg>0</ReimbursementPaidByOtherOrg>
      <OtherTransferToOtherOrg>0</OtherTransferToOtherOrg>
      <OtherTransferFromOtherOrg>0</OtherTransferFromOtherOrg>
      <TransactionsRelatedOrgsTable>
        <NameOfOtherOrganization>
          <BusinessNameLine1>frontier science foundation - hellas</BusinessNameLine1>
        </NameOfOtherOrganization>
        <TransactionType>D</TransactionType>
        <AmountInvolved>91560</AmountInvolved>
      </TransactionsRelatedOrgsTable>
    </IRS990ScheduleR>
  </ReturnData>
</Return>