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        <PersonNm>ALICE TURNER</PersonNm>
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        <PersonNm>ANN KNEBEL</PersonNm>
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        <PersonNm>DARRELL KOTTON</PersonNm>
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        <PersonNm>ERIN CARR</PersonNm>
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        <PersonNm>JENNIFER JOPP</PersonNm>
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        <PersonNm>MARK BRANTLY</PersonNm>
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      <Form990PartVIISectionAGrp>
        <PersonNm>MARK B DELVAUX</PersonNm>
        <TitleTxt>CFO</TitleTxt>
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      <Form990PartVIISectionAGrp>
        <PersonNm>SCOTT SANTARELLA</PersonNm>
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        <PersonNm>ADRIANA ARCE</PersonNm>
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        <PersonNm>ANGELA T MCBRIDE</PersonNm>
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        <PersonNm>JEANNE KUSHNER</PersonNm>
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        <PersonNm>LINDA RODRIGUEZ</PersonNm>
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        <PersonNm>RANDEL H PLANT</PersonNm>
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          <USAddress>
            <AddressLine1Txt>4521 COTTENDALE DRIVE</AddressLine1Txt>
            <CityNm>DURHAM</CityNm>
            <StateAbbreviationCd>NC</StateAbbreviationCd>
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      <ContractorCompensationGrp>
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          <USAddress>
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            <StateAbbreviationCd>NY</StateAbbreviationCd>
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          <BusinessName>
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          <USAddress>
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      <ContractorCompensationGrp>
        <ContractorName>
          <BusinessName>
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          <USAddress>
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            <StateAbbreviationCd>FL</StateAbbreviationCd>
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      <ContractorCompensationGrp>
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        <ContractorAddress>
          <USAddress>
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        <ProgramServicesAmt>1900825</ProgramServicesAmt>
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        <ProgramServicesAmt>1298187</ProgramServicesAmt>
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      <FeesForServicesLobbyingGrp>
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        <ProgramServicesAmt>698171</ProgramServicesAmt>
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        <ProgramServicesAmt>380165</ProgramServicesAmt>
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        <ManagementAndGeneralAmt>1065170</ManagementAndGeneralAmt>
        <FundraisingAmt>1124911</FundraisingAmt>
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        <EOYAmt>498946</EOYAmt>
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        <CharitableContriEvent1Amt>165000</CharitableContriEvent1Amt>
        <GrossRevenueEvent1Amt>122375</GrossRevenueEvent1Amt>
        <RentFacilityCostsEvent1Amt>68760</RentFacilityCostsEvent1Amt>
        <FoodAndBeverageEvent1Amt>6205</FoodAndBeverageEvent1Amt>
        <OtherDirectExpensesEvent1Amt>7608</OtherDirectExpensesEvent1Amt>
        <GrossRevenueEvent2Amt>0</GrossRevenueEvent2Amt>
        <GrossRevenueOtherEventsAmt>0</GrossRevenueOtherEventsAmt>
        <GrossReceiptsTotalAmt>287375</GrossReceiptsTotalAmt>
        <CharitableContributionsTotAmt>165000</CharitableContributionsTotAmt>
        <GrossRevenueTotalEventsAmt>122375</GrossRevenueTotalEventsAmt>
        <RentFcltyCostsTotalEventsAmt>68760</RentFcltyCostsTotalEventsAmt>
        <FoodAndBeverageTotalEventsAmt>6205</FoodAndBeverageTotalEventsAmt>
        <OthDirectExpnssTotalEventsAmt>7608</OthDirectExpnssTotalEventsAmt>
        <DirectExpenseSummaryEventsAmt>82573</DirectExpenseSummaryEventsAmt>
        <NetIncomeSummaryAmt>39802</NetIncomeSummaryAmt>
      </FundraisingEventInformationGrp>
    </IRS990ScheduleG>
    <IRS990ScheduleI documentId="IRS990ScheduleI" softwareId="24020961" softwareVersionNum="2024v5.1">
      <GrantRecordsMaintainedInd>true</GrantRecordsMaintainedInd>
      <RecipientTable>
        <RecipientBusinessName>
          <BusinessNameLine1Txt>UNIVERSITY OF FLORIDA</BusinessNameLine1Txt>
        </RecipientBusinessName>
        <USAddress>
          <AddressLine1Txt>1600 SW ARCHER RD</AddressLine1Txt>
          <CityNm>GAINSVILLE</CityNm>
          <StateAbbreviationCd>FL</StateAbbreviationCd>
          <ZIPCd>32610</ZIPCd>
        </USAddress>
        <RecipientEIN>596002052</RecipientEIN>
        <IRCSectionDesc>501(C)(3)</IRCSectionDesc>
        <CashGrantAmt>470549</CashGrantAmt>
        <PurposeOfGrantTxt>RESEARCH</PurposeOfGrantTxt>
      </RecipientTable>
      <RecipientTable>
        <RecipientBusinessName>
          <BusinessNameLine1Txt>REGENTS OF THE UNIV OF CALIFORNIA</BusinessNameLine1Txt>
        </RecipientBusinessName>
        <USAddress>
          <AddressLine1Txt>1850 RESEARCH PARK DR</AddressLine1Txt>
          <CityNm>DAVIS</CityNm>
          <StateAbbreviationCd>CA</StateAbbreviationCd>
          <ZIPCd>956186153</ZIPCd>
        </USAddress>
        <RecipientEIN>946036494</RecipientEIN>
        <IRCSectionDesc>501(C)(3)</IRCSectionDesc>
        <CashGrantAmt>178944</CashGrantAmt>
        <PurposeOfGrantTxt>RESEARCH</PurposeOfGrantTxt>
      </RecipientTable>
      <RecipientTable>
        <RecipientBusinessName>
          <BusinessNameLine1Txt>BRIGHAM &amp; WOMEN'S HOSPITAL INC</BusinessNameLine1Txt>
        </RecipientBusinessName>
        <USAddress>
          <AddressLine1Txt>75 FRANCIS ST</AddressLine1Txt>
          <CityNm>BOSTON</CityNm>
          <StateAbbreviationCd>MA</StateAbbreviationCd>
          <ZIPCd>02115</ZIPCd>
        </USAddress>
        <RecipientEIN>042312909</RecipientEIN>
        <IRCSectionDesc>501(C)(3)</IRCSectionDesc>
        <CashGrantAmt>174125</CashGrantAmt>
        <PurposeOfGrantTxt>RESEARCH</PurposeOfGrantTxt>
      </RecipientTable>
      <RecipientTable>
        <RecipientBusinessName>
          <BusinessNameLine1Txt>BAYLOR COLLEGE OF MEDICINE</BusinessNameLine1Txt>
        </RecipientBusinessName>
        <USAddress>
          <AddressLine1Txt>PO BOX 201361</AddressLine1Txt>
          <CityNm>HOUSTON</CityNm>
          <StateAbbreviationCd>TX</StateAbbreviationCd>
          <ZIPCd>77216</ZIPCd>
        </USAddress>
        <RecipientEIN>741613878</RecipientEIN>
        <IRCSectionDesc>501(C)(3)</IRCSectionDesc>
        <CashGrantAmt>174051</CashGrantAmt>
        <PurposeOfGrantTxt>RESEARCH</PurposeOfGrantTxt>
      </RecipientTable>
      <RecipientTable>
        <RecipientBusinessName>
          <BusinessNameLine1Txt>NATIONAL JEWISH HEALTH</BusinessNameLine1Txt>
        </RecipientBusinessName>
        <USAddress>
          <AddressLine1Txt>1400 JACKSON ST</AddressLine1Txt>
          <AddressLine2Txt>M217</AddressLine2Txt>
          <CityNm>DENVER</CityNm>
          <StateAbbreviationCd>CO</StateAbbreviationCd>
          <ZIPCd>80206</ZIPCd>
        </USAddress>
        <RecipientEIN>742044647</RecipientEIN>
        <IRCSectionDesc>501(C)(3)</IRCSectionDesc>
        <CashGrantAmt>99723</CashGrantAmt>
        <PurposeOfGrantTxt>RESEARCH</PurposeOfGrantTxt>
      </RecipientTable>
      <RecipientTable>
        <RecipientBusinessName>
          <BusinessNameLine1Txt>UNIVERISTY OF CINCINNATI</BusinessNameLine1Txt>
        </RecipientBusinessName>
        <USAddress>
          <AddressLine1Txt>4100 WEST 150TH ST</AddressLine1Txt>
          <CityNm>CLEVELAND</CityNm>
          <StateAbbreviationCd>OH</StateAbbreviationCd>
          <ZIPCd>441351304</ZIPCd>
        </USAddress>
        <RecipientEIN>316000989</RecipientEIN>
        <IRCSectionDesc>501(C)(3)</IRCSectionDesc>
        <CashGrantAmt>99500</CashGrantAmt>
        <PurposeOfGrantTxt>RESEARCH</PurposeOfGrantTxt>
      </RecipientTable>
      <RecipientTable>
        <RecipientBusinessName>
          <BusinessNameLine1Txt>CLEMSON UNIVERSITY</BusinessNameLine1Txt>
        </RecipientBusinessName>
        <USAddress>
          <AddressLine1Txt>391 COLLEGE AVE</AddressLine1Txt>
          <AddressLine2Txt>STE 303</AddressLine2Txt>
          <CityNm>CLEMSON</CityNm>
          <StateAbbreviationCd>SC</StateAbbreviationCd>
          <ZIPCd>39634</ZIPCd>
        </USAddress>
        <RecipientEIN>576000254</RecipientEIN>
        <IRCSectionDesc>501(C)(3)</IRCSectionDesc>
        <CashGrantAmt>99452</CashGrantAmt>
        <PurposeOfGrantTxt>RESEARCH</PurposeOfGrantTxt>
      </RecipientTable>
      <RecipientTable>
        <RecipientBusinessName>
          <BusinessNameLine1Txt>BOSTON MEDICAL CENTER</BusinessNameLine1Txt>
        </RecipientBusinessName>
        <USAddress>
          <AddressLine1Txt>600 HARRISON AVENUE</AddressLine1Txt>
          <CityNm>BOSTON</CityNm>
          <StateAbbreviationCd>MA</StateAbbreviationCd>
          <ZIPCd>02118</ZIPCd>
        </USAddress>
        <RecipientEIN>043314093</RecipientEIN>
        <IRCSectionDesc>501(C)(3)</IRCSectionDesc>
        <CashGrantAmt>95267</CashGrantAmt>
        <PurposeOfGrantTxt>RESEARCH</PurposeOfGrantTxt>
      </RecipientTable>
      <RecipientTable>
        <RecipientBusinessName>
          <BusinessNameLine1Txt>THE UNIVERSITY OF TEXAS</BusinessNameLine1Txt>
        </RecipientBusinessName>
        <USAddress>
          <AddressLine1Txt>PO BOX 7159</AddressLine1Txt>
          <CityNm>AUSTIN</CityNm>
          <StateAbbreviationCd>TX</StateAbbreviationCd>
          <ZIPCd>77137</ZIPCd>
        </USAddress>
        <RecipientEIN>746000203</RecipientEIN>
        <IRCSectionDesc>501(C)(3)</IRCSectionDesc>
        <CashGrantAmt>74000</CashGrantAmt>
        <PurposeOfGrantTxt>RESEARCH</PurposeOfGrantTxt>
      </RecipientTable>
      <RecipientTable>
        <RecipientBusinessName>
          <BusinessNameLine1Txt>BOSTON UNIV OF INTERNAL MEDICINE</BusinessNameLine1Txt>
        </RecipientBusinessName>
        <USAddress>
          <AddressLine1Txt>85 E NEWTON ST</AddressLine1Txt>
          <AddressLine2Txt>M-921</AddressLine2Txt>
          <CityNm>BOSTON</CityNm>
          <StateAbbreviationCd>MA</StateAbbreviationCd>
          <ZIPCd>021182308</ZIPCd>
        </USAddress>
        <RecipientEIN>510172171</RecipientEIN>
        <IRCSectionDesc>501(C)(3)</IRCSectionDesc>
        <CashGrantAmt>63368</CashGrantAmt>
        <PurposeOfGrantTxt>RESEARCH</PurposeOfGrantTxt>
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      <RecipientTable>
        <RecipientBusinessName>
          <BusinessNameLine1Txt>UNIVERSITY OF COLORADO</BusinessNameLine1Txt>
        </RecipientBusinessName>
        <USAddress>
          <AddressLine1Txt>1600 BROADWAY</AddressLine1Txt>
          <CityNm>DENVER</CityNm>
          <StateAbbreviationCd>CO</StateAbbreviationCd>
          <ZIPCd>80202</ZIPCd>
        </USAddress>
        <RecipientEIN>846000555</RecipientEIN>
        <IRCSectionDesc>501(c)(3)</IRCSectionDesc>
        <CashGrantAmt>52500</CashGrantAmt>
        <PurposeOfGrantTxt>RESEARCH</PurposeOfGrantTxt>
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      <RecipientTable>
        <RecipientBusinessName>
          <BusinessNameLine1Txt>UNIVERSITY OF KANSAS MEDICAL CENTER RESEARCH INSTITUTE INC</BusinessNameLine1Txt>
        </RecipientBusinessName>
        <USAddress>
          <AddressLine1Txt>3901 RAINBOW BLVD</AddressLine1Txt>
          <AddressLine2Txt>MS 1039</AddressLine2Txt>
          <CityNm>KANSAS CITY</CityNm>
          <StateAbbreviationCd>KS</StateAbbreviationCd>
          <ZIPCd>66160</ZIPCd>
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        <RecipientEIN>480680117</RecipientEIN>
        <IRCSectionDesc>501(C)(3)</IRCSectionDesc>
        <CashGrantAmt>48012</CashGrantAmt>
        <PurposeOfGrantTxt>RESEARCH</PurposeOfGrantTxt>
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      <RecipientTable>
        <RecipientBusinessName>
          <BusinessNameLine1Txt>UNIVERSITY OF CHICAGO</BusinessNameLine1Txt>
        </RecipientBusinessName>
        <USAddress>
          <AddressLine1Txt>5801 SOUTH ELLIS AVENUE</AddressLine1Txt>
          <CityNm>CHICAGO</CityNm>
          <StateAbbreviationCd>IL</StateAbbreviationCd>
          <ZIPCd>60637</ZIPCd>
        </USAddress>
        <RecipientEIN>362177139</RecipientEIN>
        <IRCSectionDesc>501(C)(3)</IRCSectionDesc>
        <CashGrantAmt>45894</CashGrantAmt>
        <PurposeOfGrantTxt>RESEARCH</PurposeOfGrantTxt>
      </RecipientTable>
      <RecipientTable>
        <RecipientBusinessName>
          <BusinessNameLine1Txt>CENTER FOR VETERANS RESEARCH AND EDUCATION</BusinessNameLine1Txt>
        </RecipientBusinessName>
        <USAddress>
          <AddressLine1Txt>1 VETERANS DR 151</AddressLine1Txt>
          <CityNm>MINNEAPOLIS</CityNm>
          <StateAbbreviationCd>MN</StateAbbreviationCd>
          <ZIPCd>55417</ZIPCd>
        </USAddress>
        <RecipientEIN>411652941</RecipientEIN>
        <IRCSectionDesc>501(C)(3)</IRCSectionDesc>
        <CashGrantAmt>38837</CashGrantAmt>
        <PurposeOfGrantTxt>RESEARCH</PurposeOfGrantTxt>
      </RecipientTable>
      <RecipientTable>
        <RecipientBusinessName>
          <BusinessNameLine1Txt>TRUSTEES OF BOSTON UNIVERSITY</BusinessNameLine1Txt>
        </RecipientBusinessName>
        <USAddress>
          <AddressLine1Txt>25 BUICK STREET</AddressLine1Txt>
          <AddressLine2Txt>2ND FLOOR</AddressLine2Txt>
          <CityNm>BOSTON</CityNm>
          <StateAbbreviationCd>MA</StateAbbreviationCd>
          <ZIPCd>02215</ZIPCd>
        </USAddress>
        <RecipientEIN>042103547</RecipientEIN>
        <IRCSectionDesc>501(C)(3)</IRCSectionDesc>
        <CashGrantAmt>37250</CashGrantAmt>
        <PurposeOfGrantTxt>RESEARCH</PurposeOfGrantTxt>
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      <RecipientTable>
        <RecipientBusinessName>
          <BusinessNameLine1Txt>COLUMBIA UNIVERSITY</BusinessNameLine1Txt>
        </RecipientBusinessName>
        <USAddress>
          <AddressLine1Txt>630 W 168T ST</AddressLine1Txt>
          <AddressLine2Txt>STE 39</AddressLine2Txt>
          <CityNm>NEW YORK</CityNm>
          <StateAbbreviationCd>NY</StateAbbreviationCd>
          <ZIPCd>10027</ZIPCd>
        </USAddress>
        <RecipientEIN>135598093</RecipientEIN>
        <IRCSectionDesc>501(C)(3)</IRCSectionDesc>
        <CashGrantAmt>35845</CashGrantAmt>
        <PurposeOfGrantTxt>RESEARCH</PurposeOfGrantTxt>
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      <RecipientTable>
        <RecipientBusinessName>
          <BusinessNameLine1Txt>UNIVERSITY OF UTAH</BusinessNameLine1Txt>
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        <USAddress>
          <AddressLine1Txt>201 SOUTH PRESIDENTS CIRCLE</AddressLine1Txt>
          <AddressLine2Txt>RM 159</AddressLine2Txt>
          <CityNm>SALT LAKE CITY</CityNm>
          <StateAbbreviationCd>UT</StateAbbreviationCd>
          <ZIPCd>84112</ZIPCd>
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        <RecipientEIN>876000525</RecipientEIN>
        <IRCSectionDesc>501(C)(3)</IRCSectionDesc>
        <CashGrantAmt>10499</CashGrantAmt>
        <PurposeOfGrantTxt>RESEARCH</PurposeOfGrantTxt>
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      <RecipientTable>
        <RecipientBusinessName>
          <BusinessNameLine1Txt>FEDERATION OF AMERICAN SOCIETIES FOR EXPERIMENTAL BIOLOGY</BusinessNameLine1Txt>
        </RecipientBusinessName>
        <USAddress>
          <AddressLine1Txt>9650 ROCKVILLE PIKE</AddressLine1Txt>
          <CityNm>BETHESDA</CityNm>
          <StateAbbreviationCd>MD</StateAbbreviationCd>
          <ZIPCd>20814</ZIPCd>
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        <RecipientEIN>520700497</RecipientEIN>
        <IRCSectionDesc>501(C)(3)</IRCSectionDesc>
        <CashGrantAmt>7500</CashGrantAmt>
        <PurposeOfGrantTxt>RESEARCH</PurposeOfGrantTxt>
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      <RecipientTable>
        <RecipientBusinessName>
          <BusinessNameLine1Txt>GORDON RESEARCH CONFERENCES</BusinessNameLine1Txt>
        </RecipientBusinessName>
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          <AddressLine1Txt>1400 JACKSON ST</AddressLine1Txt>
          <CityNm>DENVER</CityNm>
          <StateAbbreviationCd>CO</StateAbbreviationCd>
          <ZIPCd>80206</ZIPCd>
        </USAddress>
        <RecipientEIN>260150662</RecipientEIN>
        <IRCSectionDesc>501(C)(3)</IRCSectionDesc>
        <CashGrantAmt>7500</CashGrantAmt>
        <PurposeOfGrantTxt>RESEARCH</PurposeOfGrantTxt>
      </RecipientTable>
      <Total501c3OrgCnt>19</Total501c3OrgCnt>
      <TotalOtherOrgCnt>0</TotalOtherOrgCnt>
      <SupplementalInformationDetail>
        <FormAndLineReferenceDesc>Schedule I, Part I, Line 2 Procedures for monitoring use of grant funds</FormAndLineReferenceDesc>
        <ExplanationTxt>THE FOUNDATION HAS A GRANTS ADVISORY COMMITTEE CONSISTING OF 25 MEMBERS AND 2 STAFF MEMBERS ASSIGNED TO THE COMMITTEE. THE MEMBERSHIP OF THE COMMITTEE CONSISTS OF MEDICAL DOCTORS WHO ARE ALPHA-1 EXPERTS AND RESEARCHERS. THE COMMITTEE REVIEWS GRANT APPLICATIONS FOR QUALITY AND APPLICABILITY OF RESEARCH FUNDS. PRIOR TO ACCEPTANCE, THE PROSPECTIVE GRANTEE IS CHECKED AGAINST THE US TREASURY'S OFAC LIST. ON A QUARTERLY BASIS, ALL GRANTS ARE PEER-REVIEWED FOR PROGRESS BEFORE SUBSEQUENT PAYMENTS ARE MADE. FINAL RESEARCH REPORTS ARE SUBMITTED AND PEER-REVIEWED BEFORE FINAL GRANT PAYMENTS ARE MADE.</ExplanationTxt>
      </SupplementalInformationDetail>
    </IRS990ScheduleI>
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      <CompensationCommitteeInd>X</CompensationCommitteeInd>
      <IndependentConsultantInd>X</IndependentConsultantInd>
      <Form990OfOtherOrganizationsInd>X</Form990OfOtherOrganizationsInd>
      <WrittenEmploymentContractInd>X</WrittenEmploymentContractInd>
      <CompensationSurveyInd>X</CompensationSurveyInd>
      <BoardOrCommitteeApprovalInd>X</BoardOrCommitteeApprovalInd>
      <SeverancePaymentInd>false</SeverancePaymentInd>
      <SupplementalNonqualRtrPlanInd>false</SupplementalNonqualRtrPlanInd>
      <EquityBasedCompArrngmInd>false</EquityBasedCompArrngmInd>
      <CompBasedOnRevenueOfFlngOrgInd>false</CompBasedOnRevenueOfFlngOrgInd>
      <CompBsdOnRevRelatedOrgsInd>false</CompBsdOnRevRelatedOrgsInd>
      <CompBsdNetEarnsFlngOrgInd>false</CompBsdNetEarnsFlngOrgInd>
      <CompBsdNetEarnsRltdOrgsInd>false</CompBsdNetEarnsRltdOrgsInd>
      <AnyNonFixedPaymentsInd>false</AnyNonFixedPaymentsInd>
      <InitialContractExceptionInd>false</InitialContractExceptionInd>
      <RltdOrgOfficerTrstKeyEmplGrp>
        <PersonNm>MARK B DELVAUX</PersonNm>
        <TitleTxt>CFO</TitleTxt>
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        <OtherCompensationFilingOrgAmt>0</OtherCompensationFilingOrgAmt>
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        <NontaxableBenefitsRltdOrgsAmt>0</NontaxableBenefitsRltdOrgsAmt>
        <TotalCompensationFilingOrgAmt>100000</TotalCompensationFilingOrgAmt>
        <TotalCompensationRltdOrgsAmt>0</TotalCompensationRltdOrgsAmt>
        <CompReportPrior990FilingOrgAmt>0</CompReportPrior990FilingOrgAmt>
        <CompReportPrior990RltdOrgsAmt>0</CompReportPrior990RltdOrgsAmt>
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      <RltdOrgOfficerTrstKeyEmplGrp>
        <PersonNm>SCOTT SANTARELLA</PersonNm>
        <TitleTxt>PRESIDENT AND CEO</TitleTxt>
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        <PersonNm>ANGELA T MCBRIDE</PersonNm>
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        <OtherCompensationFilingOrgAmt>0</OtherCompensationFilingOrgAmt>
        <OtherCompensationRltdOrgsAmt>0</OtherCompensationRltdOrgsAmt>
        <DeferredCompensationFlngOrgAmt>7466</DeferredCompensationFlngOrgAmt>
        <DeferredCompRltdOrgsAmt>0</DeferredCompRltdOrgsAmt>
        <NontaxableBenefitsFilingOrgAmt>14259</NontaxableBenefitsFilingOrgAmt>
        <NontaxableBenefitsRltdOrgsAmt>0</NontaxableBenefitsRltdOrgsAmt>
        <TotalCompensationFilingOrgAmt>157721</TotalCompensationFilingOrgAmt>
        <TotalCompensationRltdOrgsAmt>0</TotalCompensationRltdOrgsAmt>
        <CompReportPrior990FilingOrgAmt>0</CompReportPrior990FilingOrgAmt>
        <CompReportPrior990RltdOrgsAmt>0</CompReportPrior990RltdOrgsAmt>
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      <RltdOrgOfficerTrstKeyEmplGrp>
        <PersonNm>RANDEL H PLANT</PersonNm>
        <TitleTxt>SENIOR DIRECTOR OF RESEARCH PROGRAMS</TitleTxt>
        <BaseCompensationFilingOrgAmt>158473</BaseCompensationFilingOrgAmt>
        <CompensationBasedOnRltdOrgsAmt>0</CompensationBasedOnRltdOrgsAmt>
        <BonusFilingOrganizationAmount>0</BonusFilingOrganizationAmount>
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        <OtherCompensationFilingOrgAmt>0</OtherCompensationFilingOrgAmt>
        <OtherCompensationRltdOrgsAmt>0</OtherCompensationRltdOrgsAmt>
        <DeferredCompensationFlngOrgAmt>8772</DeferredCompensationFlngOrgAmt>
        <DeferredCompRltdOrgsAmt>0</DeferredCompRltdOrgsAmt>
        <NontaxableBenefitsFilingOrgAmt>14148</NontaxableBenefitsFilingOrgAmt>
        <NontaxableBenefitsRltdOrgsAmt>0</NontaxableBenefitsRltdOrgsAmt>
        <TotalCompensationFilingOrgAmt>181393</TotalCompensationFilingOrgAmt>
        <TotalCompensationRltdOrgsAmt>0</TotalCompensationRltdOrgsAmt>
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        <CompReportPrior990RltdOrgsAmt>0</CompReportPrior990RltdOrgsAmt>
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      <SupplementalInformationDetail>
        <FormAndLineReferenceDesc>Schedule J, Part II COMPENSATION FROM AN UNRELATED ORGANIZATION OR INDIVIDUAL</FormAndLineReferenceDesc>
        <ExplanationTxt>NAME - MARK B. DELVAUX, COMPENSATION FROM UNRELATED ORGANIZATION - 100000, NAME OF UNRELATED ORGANIZATION - ALPHANET INC., TYPE OF COMPENSATION - ADMINISTRATIVE SERVICES AGREEMENT</ExplanationTxt>
      </SupplementalInformationDetail>
    </IRS990ScheduleJ>
    <IRS990ScheduleO documentId="IRS990ScheduleO" softwareId="24020961" softwareVersionNum="2024v5.1">
      <SupplementalInformationDetail>
        <FormAndLineReferenceDesc>Form 990, Part III, Line 4d Description of other program services</FormAndLineReferenceDesc>
        <ExplanationTxt>(Expenses $ 526,408 including grants of $ 0)(Revenue $ 0) ALPHA-1 EDUCATION DAYS PROVIDE ACCESS TO CURRENT MEDICAL INFORMATION AND RESOURCES TO HUNDREDS OF ALPHAS, THEIR FAMILIES, AND CAREGIVERS.</ExplanationTxt>
      </SupplementalInformationDetail>
      <SupplementalInformationDetail>
        <FormAndLineReferenceDesc>Form 990, Part III, Line 4d Description of other program services</FormAndLineReferenceDesc>
        <ExplanationTxt>(Expenses $ 2,435,566 including grants of $ 0)(Revenue $ 0) OTHER ALPHA-1 SERVICES INCLUDE PATIENT EDUCATION (MATERIALS, WEBSITE, ETC), A PATIENT SUPPORT NETWORK, AND A TARGETED DETECTION PROGRAM.</ExplanationTxt>
      </SupplementalInformationDetail>
      <SupplementalInformationDetail>
        <FormAndLineReferenceDesc>Form 990, Part III, Line 4d Description of other program services</FormAndLineReferenceDesc>
        <ExplanationTxt>(Expenses $ 411,454 including grants of $ 0)(Revenue $ 0) THE MISSION OF ALPHA-1 GLOBAL IS TO DEVELOP A COLLABORATIVE GLOBAL NETWORK OF ALPHA-1 PATIENT LEADERS, PHYSICIANS, AND RESEARCHERS.</ExplanationTxt>
      </SupplementalInformationDetail>
      <SupplementalInformationDetail>
        <FormAndLineReferenceDesc>Form 990, Part III, Line 4d Description of other program services</FormAndLineReferenceDesc>
        <ExplanationTxt>(Expenses $ 349,323 including grants of $ 0)(Revenue $ 0) THE ALPHA-1-TO-ONE MAGAZINE IS DESIGNED TO INFORM THE COMMUNITY OF RESEARCH DEVELOPMENTS, EDUCATION, ADVOCACY AND FUNDRAISING OPPORTUNITIES.</ExplanationTxt>
      </SupplementalInformationDetail>
      <SupplementalInformationDetail>
        <FormAndLineReferenceDesc>Form 990, Part III, Line 4d Description of other program services</FormAndLineReferenceDesc>
        <ExplanationTxt>(Expenses $ 281,906 including grants of $ 0)(Revenue $ 0) THE FOUNDATION'S PUBLIC POLICY PROGRAM MONITORS RELEVANT LEGISLATION AND REGULATORY ISSUES AND PUBLICIZES THE FOUNDATION'S POSITIONS ON SUCH ISSUES.</ExplanationTxt>
      </SupplementalInformationDetail>
      <SupplementalInformationDetail>
        <FormAndLineReferenceDesc>Form 990, Part VI, Line 11b Review of form 990 by governing body</FormAndLineReferenceDesc>
        <ExplanationTxt>THE FORM 990 IS PROVIDED TO MEMBERS OF MANAGEMENT AND THE BOARD OF DIRECTORS FOR REVIEW PRIOR TO FILING.</ExplanationTxt>
      </SupplementalInformationDetail>
      <SupplementalInformationDetail>
        <FormAndLineReferenceDesc>Form 990, Part VI, Line 12c Conflict of interest policy</FormAndLineReferenceDesc>
        <ExplanationTxt>WRITTEN CONFLICT OF INTEREST STATEMENTS ARE OBTAINED FROM ALL OFFICERS, BOARD MEMBERS, AND COMMITTEE MEMBERS ON AN ANNUAL BASIS.</ExplanationTxt>
      </SupplementalInformationDetail>
      <SupplementalInformationDetail>
        <FormAndLineReferenceDesc>Form 990, Part VI, Line 15a Process to establish compensation of top management official</FormAndLineReferenceDesc>
        <ExplanationTxt>COMPENSATION LEVELS ARE DEVELOPED USING SALARY SURVEYS AND A REVIEW OF 990S FOR COMPARABLE NOT-FOR-PROFIT ORGANIZATIONS.</ExplanationTxt>
      </SupplementalInformationDetail>
      <SupplementalInformationDetail>
        <FormAndLineReferenceDesc>Form 990, Part VI, Line 19 Required documents available to the public</FormAndLineReferenceDesc>
        <ExplanationTxt>AUDITED FINANCIAL STATEMENTS ARE AVAILABLE ON WWW.ALPHA1.ORG. GOVERNING DOCUMENTS AND THE CONFLICT OF INTEREST POLICY ARE AVAILABLE UPON REQUEST.</ExplanationTxt>
      </SupplementalInformationDetail>
      <SupplementalInformationDetail>
        <FormAndLineReferenceDesc>Form 990, Part IX, Line 11g Other Fees</FormAndLineReferenceDesc>
        <ExplanationTxt>OTHER CONTRACT SERVICES - Total Expense: 2752874, Program Service Expense: 2472460, Management and General Expenses: 175984, Fundraising Expenses: 104430;</ExplanationTxt>
      </SupplementalInformationDetail>
      <SupplementalInformationDetail>
        <FormAndLineReferenceDesc>Form 990, Part XI, Line 9 Other changes in net assets or fund balances</FormAndLineReferenceDesc>
        <ExplanationTxt>CHANGES ATTRIBUTED TO INCOME FROM AFFILIATE - -374141; Total - -374141;</ExplanationTxt>
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          <AddressLine1Txt>3300 PONCE DE LEON BLVD</AddressLine1Txt>
          <CityNm>CORAL GABLES</CityNm>
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        <PrimaryActivitiesTxt>DETECTING RISK OF ALPHA-1 ANTITRYPSIN DEFICIENCY (AATD)</PrimaryActivitiesTxt>
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        <PrimaryActivitiesTxt>DRUG THERAPIES</PrimaryActivitiesTxt>
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