STRATEGY STUDIO / NONPROFIT PEOPLE SEARCH

BENAROYA RESEARCH INSTITUTE AT VIRGINIA MASON: Form 990, tax year 2019

View the entire original 990 at ProPublica ↗

Organization
BENAROYA RESEARCH INSTITUTE AT VIRGINIA MASON (EIN 91-0653422)
Tax period
2019-01-01 to 2019-12-31
Filed
2020-11-11
IRS object ID
202013169349303241
Schema version
2019v5.1
Source
Download XML · Original 990 at ProPublica

Every field in the e-filed return. Faint text is the IRS element name, for citing.

Return header ReturnHeader

FieldValueIRS element (for citing)
Return2020-11-11T11:44:59-00:00ReturnTs
Tax Period End2019-12-31TaxPeriodEndDt

Preparer Firm PreparerFirmGrp

Preparer Firm Name PreparerFirmName

FieldValueIRS element (for citing)
Business Name Line1KPMG LLPBusinessNameLine1Txt

Preparer US Address PreparerUSAddress

FieldValueIRS element (for citing)
Address Line11918 8th Avenue Suite 2900AddressLine1Txt
CitySeattleCityNm
State AbbreviationWAStateAbbreviationCd
ZIP98101ZIPCd
FieldValueIRS element (for citing)
Return Type990ReturnTypeCd
Tax Period Begin2019-01-01TaxPeriodBeginDt

Filer Filer

FieldValueIRS element (for citing)
EIN910653422EIN

Business Name BusinessName

FieldValueIRS element (for citing)
Business Name Line1Benaroya Research Institute at Virginia MasonBusinessNameLine1Txt
FieldValueIRS element (for citing)
Business Name ControlBENABusinessNameControlTxt
Phone2063426500PhoneNum

US Address USAddress

FieldValueIRS element (for citing)
Address Line11201 Ninth AvenueAddressLine1Txt
CitySeattleCityNm
State AbbreviationWAStateAbbreviationCd
ZIP98101ZIPCd

Business Officer BusinessOfficerGrp

FieldValueIRS element (for citing)
PersonMichael LabosierPersonNm
Person TitleChief Financial OfficerPersonTitleTxt
Signature2020-11-11SignatureDt
Discuss With Paid PreparerYes (true)DiscussWithPaidPreparerInd

Preparer Person PreparerPersonGrp

FieldValueIRS element (for citing)
Preparer PersonSue RobisonPreparerPersonNm
Phone2069134000PhoneNum
Preparation2020-11-11PreparationDt

Filing Security Information FilingSecurityInformation

IP Address IPAddress

FieldValueIRS element (for citing)
I Pv4 Address204.147.223.1IPv4AddressTxt
FieldValueIRS element (for citing)
IP2020-11-11IPDt
IP Tm19:42:56IPTm
IP TimezonePSIPTimezoneCd
Filing License TypePFilingLicenseTypeCd
At Submission Creation Device Id2D777907B0975C575C8D1E5F6EEE6AF7977F0150AtSubmissionCreationDeviceId
At Submission Filing Device IdD8897A10968BD4A76AAFC1D10C660AAB2141E34AAtSubmissionFilingDeviceId
FieldValueIRS element (for citing)
Tax2019TaxYr
Build TS2021-01-29 14:40:06ZBuildTS

Form 990 IRS990

FieldValueIRS element (for citing)
Principal OfficerJane Buckner MDPrincipalOfficerNm

US Address USAddress

FieldValueIRS element (for citing)
Address Line11201 Ninth AvenueAddressLine1Txt
CitySeattleCityNm
State AbbreviationWAStateAbbreviationCd
ZIP981012795ZIPCd
FieldValueIRS element (for citing)
Gross Receipts$73,469,519GrossReceiptsAmt
Group Return For AffiliatesfalseGroupReturnForAffiliatesInd
Organization501c3Yes (X)Organization501c3Ind
Website Addressbenaroyaresearch.orgWebsiteAddressTxt
Type Of Organization CorpYes (X)TypeOfOrganizationCorpInd
Formation1956FormationYr
Legal Domicile StateWALegalDomicileStateCd
Activity Or MissionTo advance the science that will predict, prevent, reverse, and cure diseases of the immune system.ActivityOrMissionDesc
Voting Members Governing Body21VotingMembersGoverningBodyCnt
Voting Members Independent16VotingMembersIndependentCnt
Total Employee336TotalEmployeeCnt
Total Volunteers7TotalVolunteersCnt
Total Gross UBI$0TotalGrossUBIAmt
PY Contributions Grants$59,023,034PYContributionsGrantsAmt
CY Contributions Grants$62,867,601CYContributionsGrantsAmt
PY Program Service Revenue$8,229,643PYProgramServiceRevenueAmt
CY Program Service Revenue$9,656,398CYProgramServiceRevenueAmt
PY Investment Income$191,489PYInvestmentIncomeAmt
CY Investment Income$322,628CYInvestmentIncomeAmt
PY Other Revenue$347,680PYOtherRevenueAmt
CY Other Revenue$432,312CYOtherRevenueAmt
PY Total Revenue$67,791,846PYTotalRevenueAmt
CY Total Revenue$73,278,939CYTotalRevenueAmt
PY Grants And Similar Paid$22,634,522PYGrantsAndSimilarPaidAmt
CY Grants And Similar Paid$23,652,782CYGrantsAndSimilarPaidAmt
CY Benefits Paid To Members$0CYBenefitsPaidToMembersAmt
PY Salaries Comp Emp Bnft Paid$26,095,485PYSalariesCompEmpBnftPaidAmt
CY Salaries Comp Emp Bnft Paid$29,080,641CYSalariesCompEmpBnftPaidAmt
CY Total Prof Fndrsng Expns$0CYTotalProfFndrsngExpnsAmt
CY Total Fundraising Expense$0CYTotalFundraisingExpenseAmt
PY Other Expenses$18,050,564PYOtherExpensesAmt
CY Other Expenses$18,713,253CYOtherExpensesAmt
PY Total Expenses$66,780,571PYTotalExpensesAmt
CY Total Expenses$71,446,676CYTotalExpensesAmt
PY Revenues Less Expenses$1,011,275PYRevenuesLessExpensesAmt
CY Revenues Less Expenses$1,832,263CYRevenuesLessExpensesAmt
Total Assets BOY$84,112,856TotalAssetsBOYAmt
Total Assets EOY$95,747,100TotalAssetsEOYAmt
Total Liabilities BOY$39,800,841TotalLiabilitiesBOYAmt
Total Liabilities EOY$45,073,162TotalLiabilitiesEOYAmt
Net Assets Or Fund Balances BOY$44,312,015NetAssetsOrFundBalancesBOYAmt
Net Assets Or Fund Balances EOY$50,673,938NetAssetsOrFundBalancesEOYAmt
Info In Schedule O Part IIIYes (X)InfoInScheduleOPartIIIInd
MissionAdvancing the science that will predict, prevent, reverse, and cure diseases of the immune system such as autoimmune disease, allergy, and asthma.MissionDesc
Significant New Program SrvcfalseSignificantNewProgramSrvcInd
Significant ChangefalseSignificantChangeInd
Expense$27,576,900ExpenseAmt
Grant$21,982,621GrantAmt
DescImmune Tolerance Network Program. See Schedule O.Desc

Prog Srvc Accom Acty2 ProgSrvcAccomActy2Grp

FieldValueIRS element (for citing)
Expense$8,899,817ExpenseAmt
Grant$1,279,738GrantAmt
DescFundamental Immunology Programs - Includes Fundamental Immunology. See Schedule O.Desc

Prog Srvc Accom Acty3 ProgSrvcAccomActy3Grp

FieldValueIRS element (for citing)
Expense$9,436,609ExpenseAmt
Grant$158,099GrantAmt
DescTranslational, Clinical, and Systems Programs - Includes Translational, Systems, Interventional, and CRP. See Schedule O.Desc
FieldValueIRS element (for citing)
Total Other Prog Srvc Expense$13,057,014TotalOtherProgSrvcExpenseAmt
Total Other Prog Srvc Grant$232,324TotalOtherProgSrvcGrantAmt
Total Other Prog Srvc Revenue$9,656,398TotalOtherProgSrvcRevenueAmt
Total Program Service Expenses$58,970,340TotalProgramServiceExpensesAmt
Described In Section501c3Yes (true)DescribedInSection501c3Ind
Schedule B RequiredYes (true)ScheduleBRequiredInd
Political Campaign ActyfalsePoliticalCampaignActyInd
Lobbying ActivitiesYes (true)LobbyingActivitiesInd
Subject To Proxy TaxfalseSubjectToProxyTaxInd
Donor Advised FundfalseDonorAdvisedFundInd
Conservation EasementsfalseConservationEasementsInd
Collections Of ArtfalseCollectionsOfArtInd
Credit CounselingfalseCreditCounselingInd
Donor Rstr Or Quasi EndowmentsYes (true)DonorRstrOrQuasiEndowmentsInd
Report Land Building EquipmentYes (true)ReportLandBuildingEquipmentInd
Report Investments Other SecYes (true)ReportInvestmentsOtherSecInd
Report Program Related InvstfalseReportProgramRelatedInvstInd
Report Other AssetsfalseReportOtherAssetsInd
Report Other LiabilitiesYes (true)ReportOtherLiabilitiesInd
Include FIN48 FootnotefalseIncludeFIN48FootnoteInd
Independent Audit Fincl StmtYes (true)IndependentAuditFinclStmtInd
Consolidated Audit Fincl StmtfalseConsolidatedAuditFinclStmtInd
School OperatingfalseSchoolOperatingInd
Foreign OfficefalseForeignOfficeInd
Foreign ActivitiesYes (true)ForeignActivitiesInd
More Than5000 K To OrgYes (true)MoreThan5000KToOrgInd
More Than5000 K To IndividualsfalseMoreThan5000KToIndividualsInd
Professional FundraisingfalseProfessionalFundraisingInd
Fundraising ActivitiesfalseFundraisingActivitiesInd
Gaming ActivitiesfalseGamingActivitiesInd
Operate HospitalfalseOperateHospitalInd
Grants To OrganizationsYes (true)GrantsToOrganizationsInd
Grants To IndividualsfalseGrantsToIndividualsInd
Schedule J RequiredYes (true)ScheduleJRequiredInd
Tax Exempt BondsYes (true)TaxExemptBondsInd
Invest Tax Exempt BondsfalseInvestTaxExemptBondsInd
Escrow AccountfalseEscrowAccountInd
On Behalf Of IssuerYes (true)OnBehalfOfIssuerInd
Engaged In Excess Benefit TransfalseEngagedInExcessBenefitTransInd
PY Excess Benefit TransfalsePYExcessBenefitTransInd
Loan OutstandingfalseLoanOutstandingInd
Grant To Related PersonfalseGrantToRelatedPersonInd
Business Rln With Org MemfalseBusinessRlnWithOrgMemInd
Business Rln With Fam MemfalseBusinessRlnWithFamMemInd
Business Rln With35 Ctrl EntfalseBusinessRlnWith35CtrlEntInd
Deductible Non Cash ContrifalseDeductibleNonCashContriInd
Deductible Art ContributionfalseDeductibleArtContributionInd
Terminate OperationsfalseTerminateOperationsInd
Partial LiquidationfalsePartialLiquidationInd
Disregarded EntityfalseDisregardedEntityInd
Related EntityYes (true)RelatedEntityInd
Related Organization Ctrl EntfalseRelatedOrganizationCtrlEntInd
Transaction With Control EntfalseTransactionWithControlEntInd
Trnsfr Exmpt Non Chrtbl Rltd OrgfalseTrnsfrExmptNonChrtblRltdOrgInd
Activities Conducted PrtshpfalseActivitiesConductedPrtshpInd
Schedule O RequiredYes (true)ScheduleORequiredInd
IRP Document82IRPDocumentCnt
IRP Document W2 G0IRPDocumentW2GCnt
Backup Wthld ComplianceYes (true)BackupWthldComplianceInd
Employee336EmployeeCnt
Employment Tax Returns FiledYes (true)EmploymentTaxReturnsFiledInd
Unrelated Bus Incm Over LimitfalseUnrelatedBusIncmOverLimitInd
Foreign Financial AccountfalseForeignFinancialAccountInd
Prohibited Tax Shelter TransfalseProhibitedTaxShelterTransInd
Taxable Party NotificationfalseTaxablePartyNotificationInd
Nondeductible ContributionsfalseNondeductibleContributionsInd
Quid Pro Quo ContributionsfalseQuidProQuoContributionsInd
Form8282 Property Disposed OffalseForm8282PropertyDisposedOfInd
Rcv Fnds To Pay Prsnl Bnft CntrctfalseRcvFndsToPayPrsnlBnftCntrctInd
Pay Premiums Prsnl Bnft CntrctfalsePayPremiumsPrsnlBnftCntrctInd
Indoor Tanning ServicesfalseIndoorTanningServicesInd
Subj To Tax Rmnrtn Ex Prcht PymtfalseSubjToTaxRmnrtnExPrchtPymtInd
Subject To Excs Tax Net Invst IncfalseSubjectToExcsTaxNetInvstIncInd
Info In Schedule O Part VIYes (X)InfoInScheduleOPartVIInd
Governing Body Voting Members21GoverningBodyVotingMembersCnt
Independent Voting Member16IndependentVotingMemberCnt
Family Or Business RlnfalseFamilyOrBusinessRlnInd
Delegation Of Mgmt DutiesfalseDelegationOfMgmtDutiesInd
Change To Org DocumentsfalseChangeToOrgDocumentsInd
Material Diversion Or MisusefalseMaterialDiversionOrMisuseInd
Members Or StockholdersYes (true)MembersOrStockholdersInd
Election Of Board MembersYes (true)ElectionOfBoardMembersInd
Decisions Subject To ApprovaYes (true)DecisionsSubjectToApprovaInd
Minutes Of Governing BodyYes (true)MinutesOfGoverningBodyInd
Minutes Of CommitteesYes (true)MinutesOfCommitteesInd
Officer Mailing AddressfalseOfficerMailingAddressInd
Local ChaptersfalseLocalChaptersInd
Form990 Provided To Gvrn BodyYes (true)Form990ProvidedToGvrnBodyInd
Conflict Of Interest PolicyYes (true)ConflictOfInterestPolicyInd
Annual Disclosure Covered PrsnYes (true)AnnualDisclosureCoveredPrsnInd
Regular Monitoring EnfrcYes (true)RegularMonitoringEnfrcInd
Whistleblower PolicyYes (true)WhistleblowerPolicyInd
Document Retention PolicyYes (true)DocumentRetentionPolicyInd
Compensation Process CEOYes (true)CompensationProcessCEOInd
Compensation Process OtherYes (true)CompensationProcessOtherInd
Investment In Joint VenturefalseInvestmentInJointVentureInd
States Where Copy Of Return Is FldWAStatesWhereCopyOfReturnIsFldCd
Upon RequestYes (X)UponRequestInd

Books In Care Of Detail BooksInCareOfDetail

FieldValueIRS element (for citing)
PersonMichael Labosier CFOPersonNm
Phone2063426505PhoneNum

US Address USAddress

FieldValueIRS element (for citing)
Address Line11201 Ninth AvenueAddressLine1Txt
CitySeattleCityNm
State AbbreviationWAStateAbbreviationCd
ZIP98101ZIPCd

Form990 Part VII Section A Form990PartVIISectionAGrp (30 entries)

TitleTitleTxtAverage Hours Per WeekAverageHoursPerWeekRtAverage Hours Per Week Rltd OrgAverageHoursPerWeekRltdOrgRtIndividual Trustee Or DirectorIndividualTrusteeOrDirectorIndReportable Comp From OrgReportableCompFromOrgAmtReportable Comp From Rltd OrgReportableCompFromRltdOrgAmtOther CompensationOtherCompensationAmtOfficerOfficerIndHighest Compensated EmployeeHighestCompensatedEmployeeIndKey EmployeeKeyEmployeeInd
Gary Kaplan MD
Director001.00054.00Yes (X)$0$1,661,792$331,024
David Aboulafia MD
Director001.00050.00Yes (X)$0$635,488$59,144
Joyce Lammert MD PhD
Director001.00050.00Yes (X)$0$534,963$104,561
Jane Buckner MD
Ex Officio, President040.00Yes (X)$492,418$0$26,200Yes (X)
William Kowk PhD
Research Member040.00$244,059$0$28,600Yes (X)
Carla Greenbaum MD
Director040.00Yes (X)$238,252$0$31,562
Steven Ziegler PhD
Director of Academic Affairs040.00$234,294$0$22,978Yes (X)
Margaret McCormick PhD
Executive Director Chief Operating Officer040.00$218,634$0$30,800Yes (X)
Michael Labosier
Chief Financial Officer040.00$191,450$0$25,562Yes (X)
Bolong Cao
Business Development Director, Business Development040.00$186,128$0$29,474Yes (X)
Lynn Rose
Director of Scientific Administration040.00$190,130$0$22,010Yes (X)
Daniel Campbell PhD
Center Director of Discovery Science040.00$186,514$0$17,729Yes (X)
Gerald Nepom MD PhD
Program Director, ITN024.00$158,330$0$27,444Yes (X)
Homer Lane
Executive Director Chief Financial Officer040.00$168,551$0$6,985Yes (X)
Catherine Zimmerman
Director001.00Yes (X)$0$0$0
Jeffrey S Wortley
Director, Treasurer001.00Yes (X)$0$0$0Yes (X)
Christopher Wilson MD
Director001.00Yes (X)$0$0$0
David Williams
Director001.00Yes (X)$0$0$0
Diane St John
Director, Secretary001.00Yes (X)$0$0$0Yes (X)
Proctor Shenk
Director001.00Yes (X)$0$0$0
Nabil Istafanous
Director001.00Yes (X)$0$0$0
Paul Hughes
Director001.00Yes (X)$0$0$0
Michael Gallatin
Director001.00Yes (X)$0$0$0
Frank Dvorak PhD
Director, Vice-Chair001.00Yes (X)$0$0$0Yes (X)
Carla DewBerry
Director, Chair001.00Yes (X)$0$0$0Yes (X)
Tom Cohen
Director001.00Yes (X)$0$0$0
Rebecca Campbell
Director001.00Yes (X)$0$0$0
Ben Reiber
Director001.00Yes (X)$0$0$0
Kirk Nelson
Director001.00Yes (X)$0$0$0
Robert Williams
Director001.00002.00Yes (X)$0$0$0
FieldValueIRS element (for citing)
Total Reportable Comp From Org$2,508,760TotalReportableCompFromOrgAmt
Tot Reportable Comp Rltd Org$2,832,243TotReportableCompRltdOrgAmt
Total Other Compensation$764,073TotalOtherCompensationAmt
Indiv Rcvd Greater Than100 K53IndivRcvdGreaterThan100KCnt
Former Ofcr Employees ListedfalseFormerOfcrEmployeesListedInd
Total Comp Greater Than150 KYes (true)TotalCompGreaterThan150KInd
Compensation From Other SrcsfalseCompensationFromOtherSrcsInd

Contractor Compensation ContractorCompensationGrp (4 entries)

Address Line1ContractorAddress/USAddress/AddressLine1TxtCityContractorAddress/USAddress/CityNmState AbbreviationContractorAddress/USAddress/StateAbbreviationCdZIPContractorAddress/USAddress/ZIPCdServicesServicesDescCompensationCompensationAmt
DNA Brand Mechanics
1301 Fifth Avenue Suite 2600SeattleWA98101Professional Services$146,247
KPMG LLP
1918 Eighth Avenue Suite 2900SeattleWA98101Auditing Consulting$115,616
Riverbend Design Group LLC
414 Stewart St suite 215SeattleWA98101Web Development Digital Communications$110,310
Finley & Cook
601 N BroadwayShawneeOK74802Software Support$106,353
FieldValueIRS element (for citing)
Cntrct Rcvd Greater Than100 K4CntrctRcvdGreaterThan100KCnt
Related Organizations$3,000,000RelatedOrganizationsAmt
Government Grants$48,266,738GovernmentGrantsAmt
All Other Contributions$11,600,863AllOtherContributionsAmt
Total Contributions$62,867,601TotalContributionsAmt

Program Service Revenue ProgramServiceRevenueGrp (2 entries)

DescDescBusinessBusinessCdTotal Revenue ColumnTotalRevenueColumnAmtRelated Or Exempt Func IncomeRelatedOrExemptFuncIncomeAmt
Commercial Studies621500$4,280,875$4,280,875
Collaborative Research Core Services621500$5,375,523$5,375,523
FieldValueIRS element (for citing)
Total Program Service Revenue$9,656,398TotalProgramServiceRevenueAmt

Investment Income InvestmentIncomeGrp

FieldValueIRS element (for citing)
Total Revenue Column$322,628TotalRevenueColumnAmt
Exclusion$322,628ExclusionAmt

Gross Rents GrossRentsGrp

FieldValueIRS element (for citing)
Real$622,892RealAmt

Less Rental Expenses LessRentalExpensesGrp

FieldValueIRS element (for citing)
Real$190,580RealAmt

Rental Income Or Loss RentalIncomeOrLossGrp

FieldValueIRS element (for citing)
Real$432,312RealAmt

Net Rental Income Or Loss NetRentalIncomeOrLossGrp

FieldValueIRS element (for citing)
Total Revenue Column$432,312TotalRevenueColumnAmt
Exclusion$432,312ExclusionAmt

Total Revenue TotalRevenueGrp

FieldValueIRS element (for citing)
Total Revenue Column$73,278,939TotalRevenueColumnAmt
Related Or Exempt Func Income$9,656,398RelatedOrExemptFuncIncomeAmt
Exclusion$754,940ExclusionAmt

Grants To Domestic Orgs GrantsToDomesticOrgsGrp

FieldValueIRS element (for citing)
Total$21,460,813TotalAmt
Program Services$21,460,813ProgramServicesAmt

Grants To Domestic Individuals GrantsToDomesticIndividualsGrp

FieldValueIRS element (for citing)
Total$0TotalAmt

Foreign Grants ForeignGrantsGrp

FieldValueIRS element (for citing)
Total$2,191,969TotalAmt
Program Services$2,191,969ProgramServicesAmt

Benefits To Members BenefitsToMembersGrp

FieldValueIRS element (for citing)
Total$0TotalAmt

Comp Current Ofcr Directors CompCurrentOfcrDirectorsGrp

FieldValueIRS element (for citing)
Total$1,443,449TotalAmt
Program Services$663,622ProgramServicesAmt
Management And General$779,827ManagementAndGeneralAmt

Comp Disqual Persons CompDisqualPersonsGrp

FieldValueIRS element (for citing)
Total$0TotalAmt

Other Salaries And Wages OtherSalariesAndWagesGrp

FieldValueIRS element (for citing)
Total$20,938,237TotalAmt
Program Services$15,192,282ProgramServicesAmt
Management And General$5,745,955ManagementAndGeneralAmt

Pension Plan Contributions PensionPlanContributionsGrp

FieldValueIRS element (for citing)
Total$1,769,420TotalAmt
Program Services$1,231,506ProgramServicesAmt
Management And General$537,914ManagementAndGeneralAmt

Other Employee Benefits OtherEmployeeBenefitsGrp

FieldValueIRS element (for citing)
Total$3,230,520TotalAmt
Program Services$2,248,421ProgramServicesAmt
Management And General$982,099ManagementAndGeneralAmt

Payroll Taxes PayrollTaxesGrp

FieldValueIRS element (for citing)
Total$1,699,015TotalAmt
Program Services$1,182,504ProgramServicesAmt
Management And General$516,511ManagementAndGeneralAmt

Fees For Services Management FeesForServicesManagementGrp

FieldValueIRS element (for citing)
Total$0TotalAmt

Fees For Services Legal FeesForServicesLegalGrp

FieldValueIRS element (for citing)
Total$9,413TotalAmt
Management And General$9,413ManagementAndGeneralAmt

Fees For Services Accounting FeesForServicesAccountingGrp

FieldValueIRS element (for citing)
Total$115,616TotalAmt
Management And General$115,616ManagementAndGeneralAmt

Fees For Services Lobbying FeesForServicesLobbyingGrp

FieldValueIRS element (for citing)
Total$0TotalAmt
FieldValueIRS element (for citing)
Fees For Services Prof FundraisingFeesForServicesProfFundraising

Fees For Srvc Invst Mgmnt Fees FeesForSrvcInvstMgmntFeesGrp

FieldValueIRS element (for citing)
Total$0TotalAmt

Fees For Services Other FeesForServicesOtherGrp

FieldValueIRS element (for citing)
Total$2,343,708TotalAmt
Program Services$1,641,280ProgramServicesAmt
Management And General$702,428ManagementAndGeneralAmt

Advertising AdvertisingGrp

FieldValueIRS element (for citing)
Total$177,242TotalAmt
Program Services$745ProgramServicesAmt
Management And General$176,497ManagementAndGeneralAmt

Office Expenses OfficeExpensesGrp

FieldValueIRS element (for citing)
Total$122,182TotalAmt
Program Services$23,165ProgramServicesAmt
Management And General$99,017ManagementAndGeneralAmt

Information Technology InformationTechnologyGrp

FieldValueIRS element (for citing)
Total$1,403,630TotalAmt
Program Services$653,435ProgramServicesAmt
Management And General$750,195ManagementAndGeneralAmt

Royalties RoyaltiesGrp

FieldValueIRS element (for citing)
Total$0TotalAmt

Occupancy OccupancyGrp

FieldValueIRS element (for citing)
Total$3,401,852TotalAmt
Program Services$2,805,144ProgramServicesAmt
Management And General$596,708ManagementAndGeneralAmt

Travel TravelGrp

FieldValueIRS element (for citing)
Total$347,489TotalAmt
Program Services$268,212ProgramServicesAmt
Management And General$79,277ManagementAndGeneralAmt

Pymt Travel Entrtnmnt Pub Ofcl PymtTravelEntrtnmntPubOfclGrp

FieldValueIRS element (for citing)
Total$0TotalAmt

Conferences Meetings ConferencesMeetingsGrp

FieldValueIRS element (for citing)
Total$114,501TotalAmt
Program Services$84,941ProgramServicesAmt
Management And General$29,560ManagementAndGeneralAmt

Interest InterestGrp

FieldValueIRS element (for citing)
Total$758,201TotalAmt
Program Services$659,635ProgramServicesAmt
Management And General$98,566ManagementAndGeneralAmt

Payments To Affiliates PaymentsToAffiliatesGrp

FieldValueIRS element (for citing)
Total$0TotalAmt

Depreciation Depletion DepreciationDepletionGrp

FieldValueIRS element (for citing)
Total$3,254,492TotalAmt
Program Services$2,602,540ProgramServicesAmt
Management And General$651,952ManagementAndGeneralAmt

Insurance InsuranceGrp

FieldValueIRS element (for citing)
Total$57,358TotalAmt
Management And General$57,358ManagementAndGeneralAmt

Other Expenses OtherExpensesGrp (4 entries)

DescDescTotalTotalAmtProgram ServicesProgramServicesAmtManagement And GeneralManagementAndGeneralAmt
Supplies and Miscellaneous Expenses$4,446,355$4,322,029$124,326
Other Purchased Services$380,574$243,263$137,311
Patient Costs$976,976$976,976
Research Participants Expenses$341,518$341,448$70

All Other Expenses AllOtherExpensesGrp

FieldValueIRS element (for citing)
Total$462,146TotalAmt
Program Services$176,410ProgramServicesAmt
Management And General$285,736ManagementAndGeneralAmt

Total Functional Expenses TotalFunctionalExpensesGrp

FieldValueIRS element (for citing)
Total$71,446,676TotalAmt
Program Services$58,970,340ProgramServicesAmt
Management And General$12,476,336ManagementAndGeneralAmt
Fundraising$0FundraisingAmt

Cash Non Interest Bearing CashNonInterestBearingGrp

FieldValueIRS element (for citing)
BOY$5,711,406BOYAmt
EOY$5,968,573EOYAmt

Savings And Temp Cash Invst SavingsAndTempCashInvstGrp

FieldValueIRS element (for citing)
BOY$576,745BOYAmt
EOY$1,346,562EOYAmt

Pledges And Grants Receivable PledgesAndGrantsReceivableGrp

FieldValueIRS element (for citing)
BOY$11,995,906BOYAmt
EOY$13,407,687EOYAmt

Accounts Receivable AccountsReceivableGrp

FieldValueIRS element (for citing)
BOY$1,591,784BOYAmt
EOY$2,190,375EOYAmt

Prepaid Expenses Defrd Charges PrepaidExpensesDefrdChargesGrp

FieldValueIRS element (for citing)
BOY$509,432BOYAmt
EOY$642,728EOYAmt
FieldValueIRS element (for citing)
Land Bldg Equip Cost Or Other Bss$75,226,693LandBldgEquipCostOrOtherBssAmt
Land Bldg Equip Accum Deprec$51,536,267LandBldgEquipAccumDeprecAmt

Land Bldg Equip Basis Net LandBldgEquipBasisNetGrp

FieldValueIRS element (for citing)
BOY$24,914,121BOYAmt
EOY$23,690,426EOYAmt

Investments Pub Traded Sec InvestmentsPubTradedSecGrp

FieldValueIRS element (for citing)
BOY$12,066,383BOYAmt
EOY$12,334,516EOYAmt

Investments Other Securities InvestmentsOtherSecuritiesGrp

FieldValueIRS element (for citing)
BOY$25,745,020BOYAmt
EOY$33,053,950EOYAmt

Other Assets Total OtherAssetsTotalGrp

FieldValueIRS element (for citing)
BOY$1,002,059BOYAmt
EOY$3,112,283EOYAmt

Total Assets TotalAssetsGrp

FieldValueIRS element (for citing)
BOY$84,112,856BOYAmt
EOY$95,747,100EOYAmt

Accounts Payable Accr Expnss AccountsPayableAccrExpnssGrp

FieldValueIRS element (for citing)
BOY$9,535,580BOYAmt
EOY$10,369,555EOYAmt

Deferred Revenue DeferredRevenueGrp

FieldValueIRS element (for citing)
BOY$4,548,771BOYAmt
EOY$6,925,668EOYAmt

Tax Exempt Bond Liabilities TaxExemptBondLiabilitiesGrp

FieldValueIRS element (for citing)
BOY$25,716,490BOYAmt
EOY$25,037,716EOYAmt

Other Liabilities OtherLiabilitiesGrp

FieldValueIRS element (for citing)
EOY$2,740,223EOYAmt

Total Liabilities TotalLiabilitiesGrp

FieldValueIRS element (for citing)
BOY$39,800,841BOYAmt
EOY$45,073,162EOYAmt
FieldValueIRS element (for citing)
Organization Follows FASB117Yes (X)OrganizationFollowsFASB117Ind

No Donor Restriction Net Assets NoDonorRestrictionNetAssetsGrp

FieldValueIRS element (for citing)
BOY$17,232,381BOYAmt
EOY$17,545,065EOYAmt

Donor Restriction Net Assets DonorRestrictionNetAssetsGrp

FieldValueIRS element (for citing)
BOY$27,079,634BOYAmt
EOY$33,128,873EOYAmt

Total Net Assets Fund Balance TotalNetAssetsFundBalanceGrp

FieldValueIRS element (for citing)
BOY$44,312,015BOYAmt
EOY$50,673,938EOYAmt

Tot Liab Net Assets Fund Balance TotLiabNetAssetsFundBalanceGrp

FieldValueIRS element (for citing)
BOY$84,112,856BOYAmt
EOY$95,747,100EOYAmt
FieldValueIRS element (for citing)
Reconcilation Revenue Expnss$1,832,263ReconcilationRevenueExpnssAmt
Net Unrlzd Gains Losses Invst$4,529,660NetUnrlzdGainsLossesInvstAmt
Method Of Accounting AccrualYes (X)MethodOfAccountingAccrualInd
Accountant Compile Or ReviewfalseAccountantCompileOrReviewInd
FS AuditedYes (true)FSAuditedInd

FS Audited Basis FSAuditedBasisGrp

FieldValueIRS element (for citing)
Separate Basis Fincl StmtYes (X)SeparateBasisFinclStmtInd
FieldValueIRS element (for citing)
Audit CommitteeYes (true)AuditCommitteeInd
Federal Grant Audit RequiredYes (true)FederalGrantAuditRequiredInd
Federal Grant Audit PerformedYes (true)FederalGrantAuditPerformedInd

Schedule A IRS990ScheduleA

FieldValueIRS element (for citing)
Medical Research OrganizationYes (X)MedicalResearchOrganizationInd

Hospital Name And Address HospitalNameAndAddressGrp

Supported Organization Name SupportedOrganizationName

FieldValueIRS element (for citing)
Business Name Line1Virginia Mason Medical CenterBusinessNameLine1Txt
FieldValueIRS element (for citing)
CitySeattleCityNm
State AbbreviationWAStateAbbreviationCd

Gifts Grants Contri Rcvd170 GiftsGrantsContriRcvd170Grp

FieldValueIRS element (for citing)
Current Tax Year Minus4 Years$59,709,893CurrentTaxYearMinus4YearsAmt
Current Tax Year Minus3 Years$71,346,495CurrentTaxYearMinus3YearsAmt
Current Tax Year Minus2 Years$60,243,416CurrentTaxYearMinus2YearsAmt
Current Tax Year Minus1 Year$59,023,034CurrentTaxYearMinus1YearAmt
Current Tax Year$62,867,601CurrentTaxYearAmt
Total$313,190,439TotalAmt

Total Calendar Year170 TotalCalendarYear170Grp

FieldValueIRS element (for citing)
Current Tax Year Minus4 Years$59,709,893CurrentTaxYearMinus4YearsAmt
Current Tax Year Minus3 Years$71,346,495CurrentTaxYearMinus3YearsAmt
Current Tax Year Minus2 Years$60,243,416CurrentTaxYearMinus2YearsAmt
Current Tax Year Minus1 Year$59,023,034CurrentTaxYearMinus1YearAmt
Current Tax Year$62,867,601CurrentTaxYearAmt
Total$313,190,439TotalAmt
FieldValueIRS element (for citing)
Substantial Contributors Tot$30,081,850SubstantialContributorsTotAmt
Public Support Total170$283,108,589PublicSupportTotal170Amt

Gross Investment Income170 GrossInvestmentIncome170Grp

FieldValueIRS element (for citing)
Current Tax Year Minus4 Years$430,555CurrentTaxYearMinus4YearsAmt
Current Tax Year Minus3 Years$933,027CurrentTaxYearMinus3YearsAmt
Current Tax Year Minus2 Years$994,910CurrentTaxYearMinus2YearsAmt
Current Tax Year Minus1 Year$729,749CurrentTaxYearMinus1YearAmt
Current Tax Year$945,520CurrentTaxYearAmt
Total$4,033,761TotalAmt

Other Income170 OtherIncome170Grp

FieldValueIRS element (for citing)
Current Tax Year Minus4 Years$7,021,290CurrentTaxYearMinus4YearsAmt
Current Tax Year Minus3 Years$8,553,010CurrentTaxYearMinus3YearsAmt
Current Tax Year Minus2 Years$6,781,431CurrentTaxYearMinus2YearsAmt
Current Tax Year Minus1 Year$8,229,643CurrentTaxYearMinus1YearAmt
Current Tax Year$9,656,398CurrentTaxYearAmt
Total$40,241,772TotalAmt
FieldValueIRS element (for citing)
Total Support$357,465,972TotalSupportAmt
Gross Receipts Rltd Activities$40,241,772GrossReceiptsRltdActivitiesAmt
Public Support CY1700.79200PublicSupportCY170Pct
Public Support PY1700.79680PublicSupportPY170Pct
Thirty Thr Pct Suprt Tests CY170Yes (X)ThirtyThrPctSuprtTestsCY170Ind
Public Support CY5090.00000PublicSupportCY509Pct
Investment Income CY0.00000InvestmentIncomeCYPct
Facts And Circumstances TestPart II Section B Line 10 2019 Other Income of 9,656,398 is comprised of 4,280,875 of Clinical Research Program revenue, 4,453,944 of Collaborative Research Agreement projects, 886,743 of External Core Income, and 34,836 of miscellaneous income.FactsAndCircumstancesTestTxt

Schedule B IRS990ScheduleB

Contributor Information ContributorInformationGrp

FieldValueIRS element (for citing)
ContributorRESTRICTEDContributorNum

Contributor Business Name ContributorBusinessName

FieldValueIRS element (for citing)
Business Name Line1RESTRICTEDBusinessNameLine1

Contributor US Address ContributorUSAddress

FieldValueIRS element (for citing)
Address Line1RESTRICTEDAddressLine1
Address Line2RESTRICTEDAddressLine2
CityRESTRICTEDCity
StateRESTRICTEDState
ZIP CodeRESTRICTEDZIPCode
FieldValueIRS element (for citing)
Total ContributionsRESTRICTEDTotalContributionsAmt

Schedule C IRS990ScheduleC

FieldValueIRS element (for citing)
Organization Belongs Afflt GrpYes (X)OrganizationBelongsAffltGrpInd

Total Grassroots Lobbying TotalGrassrootsLobbyingGrp

FieldValueIRS element (for citing)
Affiliated Group Total$183,519AffiliatedGroupTotalAmt

Total Direct Lobbying TotalDirectLobbyingGrp

FieldValueIRS element (for citing)
Affiliated Group Total$123,581AffiliatedGroupTotalAmt

Total Lobbying Expend TotalLobbyingExpendGrp

FieldValueIRS element (for citing)
Affiliated Group Total$307,100AffiliatedGroupTotalAmt

Other Exempt Purpose Expend OtherExemptPurposeExpendGrp

FieldValueIRS element (for citing)
Filing Organizations Total$71,446,676FilingOrganizationsTotalAmt
Affiliated Group Total$1,766,048,047AffiliatedGroupTotalAmt

Total Exempt Purpose Expend TotalExemptPurposeExpendGrp

FieldValueIRS element (for citing)
Filing Organizations Total$71,446,676FilingOrganizationsTotalAmt
Affiliated Group Total$1,766,355,147AffiliatedGroupTotalAmt

Lobbying Nontaxable Amount LobbyingNontaxableAmountGrp

FieldValueIRS element (for citing)
Filing Organizations Total$1,000,000FilingOrganizationsTotalAmt
Affiliated Group Total$1,000,000AffiliatedGroupTotalAmt

Grassroots Nontaxable GrassrootsNontaxableGrp

FieldValueIRS element (for citing)
Filing Organizations Total$250,000FilingOrganizationsTotalAmt
Affiliated Group Total$250,000AffiliatedGroupTotalAmt

Avg Lobbying Nontaxable Amount AvgLobbyingNontaxableAmountGrp

FieldValueIRS element (for citing)
Current Year Minus3$1,000,000CurrentYearMinus3Amt
Current Year Minus2$1,000,000CurrentYearMinus2Amt
Current Year Minus1$1,000,000CurrentYearMinus1Amt
Current Year$1,000,000CurrentYearAmt
Total$4,000,000TotalAmt
FieldValueIRS element (for citing)
Lobbying Ceiling$6,000,000LobbyingCeilingAmt

Avg Total Lobbying Expend AvgTotalLobbyingExpendGrp

FieldValueIRS element (for citing)
Current Year Minus3$275,782CurrentYearMinus3Amt
Current Year Minus2$284,247CurrentYearMinus2Amt
Current Year Minus1$294,038CurrentYearMinus1Amt
Current Year$307,100CurrentYearAmt
Total$1,161,167TotalAmt

Avg Grassroots Nontaxable AvgGrassrootsNontaxableGrp

FieldValueIRS element (for citing)
Current Year Minus3$250,000CurrentYearMinus3Amt
Current Year Minus2$250,000CurrentYearMinus2Amt
Current Year Minus1$250,000CurrentYearMinus1Amt
Current Year$250,000CurrentYearAmt
Total$1,000,000TotalAmt
FieldValueIRS element (for citing)
Grassroots Ceiling$1,500,000GrassrootsCeilingAmt

Avg Grassroots Lobbying Expend AvgGrassrootsLobbyingExpendGrp

FieldValueIRS element (for citing)
Current Year Minus3$163,134CurrentYearMinus3Amt
Current Year Minus2$175,480CurrentYearMinus2Amt
Current Year Minus1$180,464CurrentYearMinus1Amt
Current Year$183,519CurrentYearAmt
Total$702,597TotalAmt
FieldValueIRS element (for citing)
VolunteersfalseVolunteersInd
Paid Staff Or ManagementfalsePaidStaffOrManagementInd
Media AdvertisementsfalseMediaAdvertisementsInd
Mailings MembersfalseMailingsMembersInd
Publications Or BroadcastfalsePublicationsOrBroadcastInd
Grants Other OrganizationsfalseGrantsOtherOrganizationsInd
Direct Contact LegislatorsfalseDirectContactLegislatorsInd
Rallies DemonstrationsfalseRalliesDemonstrationsInd
Other ActivitiesfalseOtherActivitiesInd
Not Described Section501c3falseNotDescribedSection501c3Ind
Form4720 Filed4912 TaxfalseForm4720Filed4912TaxInd

Supplemental Information Detail SupplementalInformationDetail (5 entries)

Form And Line ReferenceFormAndLineReferenceDescExplanationExplanationTxt
II-A ABenaroya Research Institute at Virginia Mason, EIN 91-0653422, 1201 Ninth Avenue, Seattle, WA 98101. Non-electing member. 0 Lobbying Expenditures. Excess Lobbying Expenditures 0.Benaroya Research Institute at Virginia Mason, EIN 91-0653422, 1201 Ninth Avenue, Seattle, WA 98101. Non-electing member. 0 Lobbying Expenditures. Excess Lobbying Expenditures 0.
II-A A continuedVirginia Mason Medical Center, EIN 91-0565539, 1100 Ninth Avenue, Seattle, WA 98101. Electing member. Grassroots Lobbying Expenditures 134,909 Direct Lobbying Expenditures 63,581. Excess Lobbying Expenditures 0. Tax year ending December 31, 1998 was the first year in which Virginia Mason Medical Center made the election under Section 501h. The election was not revoked before the start of the tax year ending December 31, 2019.
II-A A continuedVirginia Mason Health System, EIN 91-1351110, 1100 Ninth Avenue, Seattle, WA 98101. Non-electing member. 0 Lobbying Expenditures. Excess Lobbying Expenditures 0
II-A A continuedVirginia Mason Institute, EIN 26-3763656, 1100 Ninth Avenue, Seattle, WA 98101. Non-electing member. 0 Lobbying Expenditures, 0 Excess Lobbying Expenditures.
II-A A continuedYakima Valley Memorial Hospital Association, EIN 91-0567263, 2811 Tieton Drive, Yakima, WA 98902. Non-electing member. 48,610 Grassroots Lobbying Expenditures 60,000 Direct Lobbying Expenditures. Excess Lobbying Expenditures 0.

Schedule D IRS990ScheduleD

FieldValueIRS element (for citing)
Incl Escrow Custodial Acct LiabfalseInclEscrowCustodialAcctLiabInd
Endowments Held Unrelated OrgfalseEndowmentsHeldUnrelatedOrgInd
Endowments Held Related OrgYes (true)EndowmentsHeldRelatedOrgInd
Related Org List Sch RYes (true)RelatedOrgListSchRInd

Land LandGrp

FieldValueIRS element (for citing)
Other Cost Or Other Basis$756,906OtherCostOrOtherBasisAmt
Book Value$756,906BookValueAmt

Buildings BuildingsGrp

FieldValueIRS element (for citing)
Other Cost Or Other Basis$49,852,993OtherCostOrOtherBasisAmt
Depreciation$30,754,795DepreciationAmt
Book Value$19,098,198BookValueAmt

Leasehold Improvements LeaseholdImprovementsGrp

FieldValueIRS element (for citing)
Other Cost Or Other Basis$215,595OtherCostOrOtherBasisAmt
Depreciation$199,672DepreciationAmt
Book Value$15,923BookValueAmt

Equipment EquipmentGrp

FieldValueIRS element (for citing)
Other Cost Or Other Basis$23,141,650OtherCostOrOtherBasisAmt
Depreciation$20,581,800DepreciationAmt
Book Value$2,559,850BookValueAmt

Other Land Buildings OtherLandBuildingsGrp

FieldValueIRS element (for citing)
Other Cost Or Other Basis$1,259,549OtherCostOrOtherBasisAmt
Book Value$1,259,549BookValueAmt
FieldValueIRS element (for citing)
Total Book Value Land Buildings$23,690,426TotalBookValueLandBuildingsAmt

Other Securities OtherSecuritiesGrp (3 entries)

DescDescBook ValueBookValueAmtMethod ValuationMethodValuationCd
Financial derivatives and other financial products
Closely-held equity interests
Interest in Net Assets of Virginia Mason Health System$33,053,950F
FieldValueIRS element (for citing)
Total Book Value Securities$33,053,950TotalBookValueSecuritiesAmt

Other Liabilities Org OtherLiabilitiesOrgGrp (2 entries)

DescDescAmtAmt
Federal income taxes
Lease liability Relates to Right-of-Use Asset$2,740,223
FieldValueIRS element (for citing)
Total Liability$2,740,223TotalLiabilityAmt
Total Rev Etc Audited Fincl Stmt$77,808,599TotalRevEtcAuditedFinclStmtAmt
Net Unrealized Gains Invst$4,529,660NetUnrealizedGainsInvstAmt
Revenue Not Reported$4,529,660RevenueNotReportedAmt
Revenue Subtotal$73,278,939RevenueSubtotalAmt
Total Revenue Per Form990$73,278,939TotalRevenuePerForm990Amt
Tot Expns Etc Audited Fincl Stmt$71,446,676TotExpnsEtcAuditedFinclStmtAmt
Expenses Subtotal$71,446,676ExpensesSubtotalAmt
Total Expenses Per Form990$71,446,676TotalExpensesPerForm990Amt

Supplemental Information Detail SupplementalInformationDetail

FieldValueIRS element (for citing)
Form And Line ReferenceX 1, Row 2FormAndLineReferenceDesc
ExplanationIn accordance with ASC topic 842 Leases, the Research Institute adopted the new standard and recorded lease liabilities over lease terms between 3 and 10 years. The leases are primarily for real estate, including off-campus outpatient facilities, medical office buildings, and corporate and administrative offices.ExplanationTxt

Schedule F IRS990ScheduleF

FieldValueIRS element (for citing)
Grant Records MaintainedYes (true)GrantRecordsMaintainedInd

Account Activities Outside US AccountActivitiesOutsideUSGrp (6 entries)

RegionRegionTxtType Of Activities ConductedTypeOfActivitiesConductedTxtSpecific Services ProvidedSpecificServicesProvidedTxtRegion Total ExpendituresRegionTotalExpendituresAmt
Europe Including Iceland and GreenlandConferencesMedical Research$29,451
East Asia and the PacificConferencesMedical Research$4,213
North AmericaConferencesMedical Research$1,283
Europe Including Iceland and GreenlandGrantMedical Research$1,789,606
East Asia and the PacificGrantMedical Research$394,025
North AmericaGrantMedical Research$8,337
FieldValueIRS element (for citing)
Subtotal Spent$2,226,915SubtotalSpentAmt
Total Spent$2,226,915TotalSpentAmt

Grants To Org Outside US GrantsToOrgOutsideUSGrp (10 entries)

RegionRegionTxtPurpose Of GrantPurposeOfGrantTxtCash GrantCashGrantAmtManner Of Cash DisbursementMannerOfCashDisbursementTxt
Europe Including Iceland and GreenlandMedical Research$811,655Wire Transfer
Europe Including Iceland and GreenlandMedical Research$596,423Wire Transfer
Europe Including Iceland and GreenlandMedical Research$231,032Wire Transfer
Europe Including Iceland and GreenlandMedical Research$134,225Wire Transfer
Europe Including Iceland and GreenlandMedical Research$16,271Wire Transfer
East Asia and the PacificMedical Research$277,258Wire Transfer
East Asia and the PacificMedical Research$96,526Wire Transfer
East Asia and the PacificMedical Research$12,494Wire Transfer
East Asia and the PacificMedical Research$7,747Wire Transfer
North AmericaMedical Research$8,337Wire Transfer
FieldValueIRS element (for citing)
Total Other Org10TotalOtherOrgCnt
Transfer To Foreign CorpfalseTransferToForeignCorpInd
Interest In Foreign TrustfalseInterestInForeignTrustInd
Foreign Corp OwnershipfalseForeignCorpOwnershipInd
Passive Foreign Investmest CofalsePassiveForeignInvestmestCoInd
Foreign PartnershipfalseForeignPartnershipInd
Boycott CountriesfalseBoycottCountriesInd

Supplemental Information Detail SupplementalInformationDetail (3 entries)

Form And Line ReferenceFormAndLineReferenceDescExplanationExplanationTxt
Part I Line 2Sub-recipient Monitoring Policy - medical research sub awards - BRI has formal policies and procedures to assure full compliance with applicable policies and laws governing federal grants. The Sub-recipient Monitoring Policy provides assurance that sub-recipients comply with federal grant regulations. This policy sets the criteria to establish eligibility of sub-recipients to provide annual audited financial reports and the annual OMB single audit report that identify compliance with federal laws and regulations. The reports are analyzed with emphasis on auditors assessment of sub-recipient internal controls and a standardized risk assessment is presented to management on each sub-recipient. A Management Letter is issued to each sub-recipient showing any findings on their OMB single audit report, and measurements are set for increased monitoring when an elevated level of risk is established. Management has communicated with an educated administrative staff regarding implementation of this policy. The Director of Grants and Contracts is responsible for monitoring sub-recipient adherence to financial regulations. The principal investigator is responsible for overseeing the satisfactory performance of the sub-award to ensure that goals are achieved. If there are unusual or unforeseen items, these will be investigated.
Part I Line 3fThe expenditures were actual expenses incurred in the region based on individual expense reports and tracking of expenditures by grant or department on the accrual basis of accounting.
Part II Line 1The expenditures were expenses incurred in the region based on award goals on the accrual basis of accounting.

Schedule I IRS990ScheduleI

FieldValueIRS element (for citing)
Grant Records MaintainedYes (true)GrantRecordsMaintainedInd

Recipient Table RecipientTable (57 entries)

Address Line1USAddress/AddressLine1TxtCityUSAddress/CityNmState AbbreviationUSAddress/StateAbbreviationCdZIPUSAddress/ZIPCdRecipient EINRecipientEINIRC SectionIRCSectionDescCash GrantCashGrantAmtPurpose Of GrantPurposeOfGrantTxt
Ann&Robert H Lurie Children's Hospital of Chicago
225 East Chicago Ave No 205ChicagoIL606112991362170833501c3$11,685Medical Research
Arkansas Children's Hospital Research Institute
One Childrens WayLittle RockAR722023591710694931501c3$46,507Medical Research
Asthma Inc
9725 3rd Ave NESeattleWA98115237219813501c3$18,988Medical Research
Children's Hosp of Philadelphia
PO Box 8550PhliladelphiaPA191781457231352166501c3$67,524Medical Research
Children's Mercy Hospital
2401 Gillham RoadKansas CityMO64101440605373501c3$41,893Medical Research
The Cleveland Clinic Foundation
9500 Euclid Avenue JJN5-001ClevelandOH44195340714585501c3$97,334Medical Research
Columbia University Trustees of
PO Box 29789New YorkNY100879789135598093501c3$80,903Medical Research
Dana-Farber Cancer Institute Inc
Attn Research AccountingBostonMA02215042263040501c3$115,073Medical Research
Denver Nephrologists PC
130 Rampart Way Suite 300BDenverCO80230840591433$13,538Medical Research
Duke University
PO Box 602651CharlotteNC282602651560532129501c3$1,287,080Medical Research
Emory University
PO Box 935084AtlantaGA311935084580566256501c3$201,493Medical Research
Feinstein Institute for Medical Research
350 Community DriveManhassetNY11030112673595501c3$167,098Medical Research
Fred Hutchinson Cancer Research Center
Mailstop J6-330SeattleWA98109237156071501c3$257,933Medical Research
Hospital for Special Surgery
535 East 70th StrNew YorkNY10021131624135501c3$12,868Medical Research
Icahn School of Medicine at Mount Sinai
One Gustave L Levy Place Box 3500New YorkNY100296574136171197501c3$1,406,824Medical Research
Indiana University
Dept 78867DetroitMI482780867356001673501c3$137,454Medical Research
Johns Hopkins University
Central Lockbox c/o B of AChicagoIL60693520595110501c3$468,431Medical Research
Jonathan Corren MD Inc
10780 Santa Monica Blvd 280Los AngelesCA90025462346264501c3$45,319Medical Research
Joslin Diabetes Center
ATTN Fiscal ServicesBostonMA022155306042203836501c3$62,425Medical Research
Massachusetts General Hospital
55 Fruit StreetBostonMA02114042697983501c3$5,841,834Medical Research
Medical University of South Carolina
19 Hagood Avenue Ste 604CharlestonSC29425576000722501c3$15,919Medical Research
MITBroad Institute
415 Main StreetCambridgeMA02142263428781501c3$8,388Medical Research
National Jewish Health
1400 Jackson Street M213DenverCO80206742044647501c3$18,521Medical Research
New York University-School of Medicine
1 Park Ave Fl 11New YorkNY10016135562308501c3$19,272Medical Research
Northwestern University
633 Clark Room G547EvanstonIL60208362167817501c3$91,798Medical Research
Ohio State University
Office of Sponsored ProgramsColumbusOH43210316025986501c3$12,616Medical Research
Polyclinic
Madison Center 904 7th AveSeattleWA98104910369070501c3$39,093Medical Research
Rockefeller University
1230 York AveNew YorkNY100656307131624158501c3$35,835Medical Research
Rutgers the State University of New Jersey
Office of Research and Sponsored PrNew BrunswickNJ089018559226001086501c3$126,221Medical Research
Sanford Research
2301 E 60th St NSioux FallsSD57104460450378501c3$81,778Medical Research
Seattle Childrens Hospital
PO Box 24728SeattleWA981240728910564748501c3$528,866Medical Research
Stanford University
PO Box 44253San FranciscoCA941444253941156365501c3$283,911Medical Research
State University of Iowa
118 S Clinton St - SCSTIowa CityIA52242426004813501c3$71,518Medical Research
St Jude Children's Research Hospital Inc
PO Box 1000 Dept 949MemphisTN381480949620646012501c3$290,310Medical Research
University Of South Florida
PO Box 864568OrlandoFL32886593102112Florida$7,679Medical Research
University of WA Grants
12455 Collections DriveChicagoIL606930001916001537Washington$1,085,117Medical Research
Univ of Minnesota Regents
NW 5957MinneapolisMN554855957416007513Minnesota$84,319Medical Research
University of Colorado-Denver
PO Box 910238DenverCO802910238846000555501c3$185,610Medical Research
University of Pennsylvania
PO Box 785541PhliladelphiaPA171785541231352685501c3$172,206Medical Research
University of Florida
PO Box 113001GainesvilleFL32611596002052501c3$13,110Medical Research
University of Texas Southwestern Medical Center
5323 Harry Hines BoulevardDallasTX75390756002868Texas$103,452Medical Research
University of Michigan
Box 223131PittsburghPA152512131386006309501c3$75,904Medical Research
University of North Carolina at Chapel Hill
PO Box 402420AtlantaGA303842420566001393501c3$91,447Medical Research
University of Massachusetts Worcester
55 Lake Avenue NorthWorcesterMA016550002043167352501c3$11,810Medical Research
University of Wisconsin Madison Board of Regents
600 Highland AveMadisonWI53792396006492Wisconsin$40,695Medical Research
University of Chicago
5841 S Maryland AveChicagoIL60637362177139501c3$11,025Medical Research
University of California San Francisco
Controllers OfficeSan FranciscoCA941430897946036493501c3$6,546,206Medical Research
University of Pittsburgh
Research/Cost AccountingPittsburghPA152517220250965591501c3$522,144Medical Research
University of Alabama at Birmingham
1720 2nd Ave SouthBirminghamAL35294636005396501c3$9,860Medical Research
University of Miami
1320 S Dixie HighwayCoral GablesFL331462926590624458501c3$6,618Medical Research
University of California Los Angeles
11000 Kinross Ave Ste 211Los AngelesCA90095956006143501c3$36,807Medical Research
University Of Texas Health Science Center Houston
7000 Fannin StHoustonTX770305400741761309Texas$30,300Medical Research
Vanderbilt University
Department of FinanceDallasTX753121236620476822501c3$140,098Medical Research
Vital Prospects Clinical Research Institute PC
7307 S Yale Ave Suite 200TulsaOK74136261814411501c3$13,903Medical Research
Washington University in St Louis
700 Rosedale Avenue Campus Box 1034St LouisMO63012460653611Missouri$10,601Medical Research
Weill Medical College of Cornell University
Attn Research AccountingNew YorkNY100226102131623978New York$220,750Medical Research
Yale University
Grant and Contract Financial AdminiNew HavenCT065081873080648973501c3$28,249Medical Research
FieldValueIRS element (for citing)
Total501c3 Org56Total501c3OrgCnt
Total Other Org1TotalOtherOrgCnt

Supplemental Information Detail SupplementalInformationDetail

FieldValueIRS element (for citing)
Form And Line ReferencePart I Line 2FormAndLineReferenceDesc
ExplanationSub-recipient Monitoring Policy - medical research sub awards - BRI has formal policies and procedures to assure full compliance with applicable policies and laws governing federal grants. The Sub-recipient Monitoring Policy provides assurance that sub-recipients comply with federal grant regulations. This policy sets the criteria to establish eligibility of sub-recipients to provide annual audited financial reports and the annual OMB single audit report that identify compliance with federal laws and regulations. The reports are analyzed with emphasis on auditors assessment of sub-recipient internal controls and a standardized risk assessment is presented to management on each sub-recipient. A Management Letter is issued to each sub-recipient showing any findings on their OMB single audit report, and measurements are set for increased monitoring when an elevated level of risk is established. Management has communicated with an educated administrative staff regarding implementation of this policy. The Director of Grants and Contracts is responsible for monitoring sub-recipient adherence to financial regulations. The principal investigator is responsible for overseeing the satisfactory performance of the sub-award to ensure that goals are achieved. If there are unusual or unforeseen items, these will be investigated.ExplanationTxt

Schedule J IRS990ScheduleJ

FieldValueIRS element (for citing)
First Class Or Charter TravelYes (X)FirstClassOrCharterTravelInd
Club Dues Or FeesYes (X)ClubDuesOrFeesInd
Written Policy Ref T And E ExpnssYes (true)WrittenPolicyRefTAndEExpnssInd
Substantiation RequiredYes (true)SubstantiationRequiredInd
Severance PaymentfalseSeverancePaymentInd
Supplemental Nonqual Rtr PlanfalseSupplementalNonqualRtrPlanInd
Equity Based Comp ArrngmfalseEquityBasedCompArrngmInd
Comp Based On Revenue Of Flng OrgfalseCompBasedOnRevenueOfFlngOrgInd
Comp Bsd On Rev Related OrgsfalseCompBsdOnRevRelatedOrgsInd
Comp Bsd Net Earns Flng OrgfalseCompBsdNetEarnsFlngOrgInd
Comp Bsd Net Earns Rltd OrgsfalseCompBsdNetEarnsRltdOrgsInd
Any Non Fixed PaymentsfalseAnyNonFixedPaymentsInd
Initial Contract ExceptionfalseInitialContractExceptionInd

Rltd Org Officer Trst Key Empl RltdOrgOfficerTrstKeyEmplGrp (14 entries)

TitleTitleTxtBase Compensation Filing OrgBaseCompensationFilingOrgAmtDeferred Compensation Flng OrgDeferredCompensationFlngOrgAmtNontaxable Benefits Filing OrgNontaxableBenefitsFilingOrgAmtTotal Compensation Filing OrgTotalCompensationFilingOrgAmtBonus Filing OrganizationBonusFilingOrganizationAmountCompensation Based On Rltd OrgsCompensationBasedOnRltdOrgsAmtBonus Related OrganizationsBonusRelatedOrganizationsAmtOther Compensation Rltd OrgsOtherCompensationRltdOrgsAmtDeferred Comp Rltd OrgsDeferredCompRltdOrgsAmtNontaxable Benefits Rltd OrgsNontaxableBenefitsRltdOrgsAmtTotal Compensation Rltd OrgsTotalCompensationRltdOrgsAmt
Michael Labosier
Chief Financial Officer$191,450$19,000$6,562$217,012
Lynn Rose
Director of Scientific Administration$188,630$19,038$2,972$212,140$1,500
Margaret McCormick PhD
Executive Director Chief Operating Officer$218,634$25,000$5,800$249,434
Steven Ziegler PhD
Director of Academic Affairs$234,294$17,866$5,112$257,272
William Kowk PhD
Research Member$244,059$25,000$3,600$272,659
Gerald Nepom MD PhD
Program Director, ITN$158,330$24,000$3,444$185,774
Gary Kaplan MD
Director$1,204,109$193,393$264,290$287,869$43,155$1,992,816
David Aboulafia MD
Director$634,300$1,188$27,343$31,801$694,632
Joyce Lammert MD PhD
Director$389,432$52,269$93,262$89,844$14,717$639,524
Carla Greenbaum MD
Director$238,252$25,000$6,562$269,814
Jane Buckner MD
Ex Officio, President$391,383$25,000$1,200$518,618$101,035
Homer Lane
Executive Director Chief Financial Officer$88,163$6,125$860$175,536$80,388
Daniel Campbell PhD
Center Director of Discovery Science$186,514$12,425$5,304$204,243
Bolong Cao
Business Development Director, Business Development$186,128$25,000$4,474$215,602

Supplemental Information Detail SupplementalInformationDetail (3 entries)

Form And Line ReferenceFormAndLineReferenceDescExplanationExplanationTxt
Part I Line 1aSocial club dues are provided to two members of the senior leadership team who use the club memberships for business purposes. These payments are treated as non-taxable.
Part I Line 3Benaroya Research Institute at Virginia Mason BRI delegates to Virginia Mason Health Systems its parent and sole member Board Compensation and Benefits Committee, a committee composed of independent Health System Board members to whom the BRI Board has delegated the authority to approve all compensation and benefits for the executive leaders of BRI. To ensure that such benefit plans are market competitive and reasonable, the Committee receives support and advice, including appropriate market comparability data from an independent compensation consultant with expertise in the health care industry and access to relevant market data. See Schedule O for additional disclosure.
Part I Line 4bThe Virginia Mason Medical Center has a Supplemental Executive Retirement Plan SERP in which certain BRI Executives participate. The SERP is a 457 f nonqualified deferred compensation plan pursuant to which plan benefits are subject to a substantial risk of forfeiture, entered into in connection with certain senior executives joining the Medical Center. The plan was approved by the Boards Compensation and Benefits Committee, a committee composed of independent board members to whom the Board delegates the authority to approve compensation and benefits to the Medical Centers most senior executives. The Committee receives advice from an independent compensation consultant to ensure that compensation and benefits, including the SERP, are market competitive and reasonable. Supplemental Executive Retirement Plans such as this are customary for senior executives in the health care industry.

Schedule K IRS990ScheduleK

Tax Exempt Bonds Issues TaxExemptBondsIssuesGrp (2 entries)

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WA Econ Devel Fin Auth-2019 Series A
A9114930020000000002019-02-26$25,716,490See Part VIfalseYes (true)false
WA Econ Devel Fin Auth-2019 Series B
B9114930020000000002019-02-26$6,000,000See Part VIfalseYes (true)false

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A$569,384$25,716,490$25,716,490Yes (true)falseYes (true)Yes (true)
B$6,000,000$5,736,573Yes (true)falseYes (true)Yes (true)$263,427

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AfalseYes (true)Yes (true)falsefalsefalseYes (true)
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Supplemental Information Detail SupplementalInformationDetail (2 entries)

Form And Line ReferenceFormAndLineReferenceDescExplanationExplanationTxt
Part I Line A Column FPurposes To currently refund WEDFA Series 2012 B bonds issued 06/01/2012, and WEDFA Series 2016 bonds issued on 06/01/2016.
Part I Line B Column FPurposes To fund research facility improvements and equipment purchases on a draw-down basis over a three-year period ending in 2022.

Schedule O IRS990ScheduleO

Supplemental Information Detail SupplementalInformationDetail (14 entries)

Form And Line ReferenceFormAndLineReferenceDescExplanationExplanationTxt
Form 990, Part III, Line 1Benaroya Research Institute at Virginia Mason BRI is one of the few research institutes in the world devoted to finding causes and cures for autoimmune disease and other diseases of the immune system including type 1 diabetes, multiple sclerosis, rheumatoid arthritis, lupus, inflammatory bowel disease, allergy and cancer. We believe a breakthrough against one of these diseases can lead to progress against them all. BRI is affiliated with the Virginia Mason Health System, which provides governance oversight, development support through the Virginia Mason Foundation as well as being a partner in clinical and translational research. In 2019, BRI launched an ambitious strategic plan with a bold mission to predict, prevent, reverse and cure diseases of the immune system to achieve our vision of a healthy immune system for everyone. Discoveries at BRI are accelerated by our talented researchers, collaborative culture and application of new technologies and data analytics. However, in order to fully realize our mission, we need to better understand what causes the immune system to fall out of balance and what we can do to restore it to health. To that end, BRI has now organized its scientific activities into four new Centers of Discovery 1 Fundamental Immunology, directed by Daniel Campbell, PhD 2 Translational Immunology, directed by Karen Cerosaletti, PhD 3 Interventional Immunology, directed by Carla Greenbaum, MD and 4 Systems Immunology, directed by Peter Linsley, PhD. The Centers work together by building on the discoveries of each, with scientists applying tools and insights across the spectrum of immune system diseases to accelerate research advances. BRI is led by President Jane H. Buckner, MD, and Executive Director/COO Margaret McCormick, PhD. In 2019, through a new funding opportunity BRI initiated a novel Gut Immunology program, which works across the Centers to unite scientists who study different aspects of the same diseases. Many of BRIs research faculty serve concurrently as affiliate professors at the University of Washington and mentor postdoctoral fellows, graduate students and summer interns.
Form 990, Part III, Line 4One unique quality of BRI is the close integration of four types of medical research - laboratory research, translational research, clinical research and systems biology - to improve lives. Our scientists collaborate to explore basic science as well as clinical applications, which is the best way to design studies with the highest potential for success. At BRI, discovery starts in the laboratory but is driven by patient issues addressed in the clinic. Selected 2019 advancements of the Immune Tolerance Network and in BRIs Centers of Discovery are highlighted as follows.
Form 990, Part III, Line 4aFunding for the Immune Tolerance Network ITN was awarded to BRIs Dr. Jerry Nepom in 2014 from the National Institute of Allergy and Infectious Disease NIAID of the National Institutes of Health NIH. The 7-year award, totaling 27 million annually supports the ITN, a research consortium established in 1999 with a primary focus on the development of new tolerogenic approaches for the treatment and prevention of disease in these clinical areas Type 1 Diabetes, Transplant, Autoimmune disease and Allergy and Asthma. As the Prime recipient of this grant, BRI is responsible for the management of the overall grant from NIAID including oversight of all aspects of the Networks infrastructure. The major activities in 2019 were diverse, but continued to center on preserving the ITNs cohesive project focused environment and its framework which has proven so successful in the management of a large cooperative agreement grant. Key outcomes in 2019 include the following 1 Cross Network Integration A top priority in this reporting period was to continue the successful ITN infrastructure which is spread across three main operational sites. This required careful planning and collaboration as the ITNs major centers of operations are geographically diverse, located in Seattle, San Francisco and Bethesda. Few changes were made to the existing network integration as the current model continues to successfully support the overall ITN program. Establishing new relationships and vital connections within the research community continued to be an ITN goal. 2 Operations and Clinical Trial Support The ITN program team at BRI issued 194 sub-awards in 2019 in support of 27 active ITN clinical trials and numerous supporting ITN mechanistic trials. 3 Supplemental Funding / Partnerships ITN central administration continued to focus on identifying additional opportunities for supplemental funding and/or funding partnerships. a Supplemental Funding Opportunities The ITN Program Team at BRI submitted two supplemental funding requests in 2019. These requests were awarded, bringing in an additional 3.17M in funding to the ITN BRI. b Partnerships The ITN continued its relationship with two pharmaceutical partners for partial funding on two ongoing ITN studies. NIAID is the clinical sponsor on both of these trials. 4 Publication Activity In 2019, 26 ITN publications were published in prestigious research journals and were presented at domestic and international research conferences. These publications represented ITN research in all therapeutic focus areas of the ITN Type 1 Diabetes, Transplant, Autoimmune disease and Allergy and Asthma. 5 Grant Renewal Application With the current ITN grant funding ending in February 2021, the preparation of the grant renewal application was a major focus in Q4, 2019. The renewal was successfully submitted, with expected award notification in late 2020.
Form 990, Part III, Line 4bCenter of Fundamental Immunology advances include 1 Linking a New Type of Cell with a Deadly Inflammatory Disorder - A research team made a discovery that lights the way to treat life-threatening complications of autoimmune and viral diseases. The discovery, published in the journal Science, could lead to new treatments for a deadly form of inflammation in children with systemic juvenile idiopathic arthritis SJIA, malaria and Kawasaki disease as well as patients with lupus. The research team found a unique type of cell, which they termed inflammatory hemophagocytes iHPCs, that eat red blood cells in MAS and malaria. They demonstrated that iHPCs develop under the influence of two specific proteins that recognize infection and are associated with autoimmune disease. Next steps will involve collaborations with pediatricians and pediatric rheumatologists to look for iHPCs in the blood of children with autoimmune disease related anemia, as well as healthy individuals, with a goal of quickly identifying potential targets for treatments. Comparisons with blood samples infected by malaria are already under way. 2 A Skin Immune Cell Discovery Challenges Assumptions about T cells - BRI scientists scrutinized a newly identified population of human immune cells in the blood that appear to have everything in common with infection-fighting T cells isolated from the skin. Scientists demonstrated that T cells that were previously assumed to stay in the skin, and are referred to as tissue-resident memory T cells, can exit skin tissue, enter the blood and circulate throughout the body. These T cells can then relocate into skin at other locations of the body. In addition to potential implications for treatment of wounds and skin infections, the identification of this cell population presents an opportunity to identify therapies for immune-related diseases that affect the skin, including scleroderma, psoriasis and a form of lymphoma called mycosis fungoides.
Form 990, Part III, Line 4cCenter for Translational Immunology is a research approach that allows scientific observations made in the basic research lab to be quickly evaluated in patient samples, refining our understanding of human disease in an expedient and systematic way. This research is translating new diagnostic and treatment approaches that may improve our ability to predict disease risk, prevent onset of disease, decrease disease progression and make treatments safer and better. The research emphasis of the BRI Translational Research Program crosses a spectrum of diseases caused by or aggravated by the immune system, including cancer and infectious disease. The BRI biorepositories, or biobank, is a collection of blood, serum and tissue samples, as well as medical histories, from healthy volunteers and individuals with diseases involving the immune system. Sample collections began in 2000. BRI scientists and physician collaborators work together to study the blood and serum samples along with medical and demographic data collected from people with autoimmune and immune-mediated diseases. These include multiple sclerosis, type 1 diabetes, lupus, rheumatoid arthritis, inflammatory bowel disease, allergy, asthma and cancer. Advancements in 2019 included the following 1 Personalized Treatments for Peanut Allergy - BRI furthered a two-pronged study to accelerate discovery of treatments for peanut allergy through a collaboration involving three BRI labs, Virginia Mason physicians and sponsors of two clinical trials. The study first investigated peanut allergy patients immune responses and classified them into subgroups. In the second part of the study, researchers are evaluating treatment options used in a pair of clinical trials to determine how specific treatments can be matched to specific patients to teach their immune systems to tolerate peanut protein. 2 Sound Life Project - BRI launched the Sound Life Project, a two-year study in which researchers will track healthy immune systems over time. Seattle-area adults in two age cohorts - 25-35 and 55-65 - began to participate in this groundbreaking study to build a baseline of knowledge about the human immune system and the influence of environmental/lifestyle factors. BRI will use this information about healthy immune systems to serve as a foundation for existing and future disease research programs. The project is in the initial phase of a research partnership led by the Allen Institute for Immunology. 3 Autoimmune Disease Research in the Down Syndrome Population - With the help of a Virginia Mason pediatrician, BRI leveraged a grant from the National Institutes of Health to build a Down syndrome DS biorepository to research the connection between DS and autoimmune disease. The collection includes blood, serum and tissue samples, as well as medical histories, from volunteers, people with DS and their relatives, with and without autoimmune diseases. The DS population has long been underrepresented in medical research, and nearly 50 percent of this population is living with at least one autoimmune disease. BRI is among the first to be awarded a grant dedicated to autoimmune disease in the DS population. 4Identifying biomarkers that predict the success of checkpoint inhibitor immunotherapy drugs used to treat certain types of cancer - Despite the success of checkpoint inhibitors at improving cancer survival rates, they do not work in all patients and often have serious side effects including sudden-autoimmune-like symptoms called immune related adverse events irAEs. BRI scientists took a much closer look at how immune response cells -- known as T cells -- are affected by checkpoint inhibitor drugs. Ultimately, the scientists hope to identify T cell biomarkers that predict which patients are at the lowest or highest risk for autoimmune effects after receiving checkpoint inhibitors. They also explored ways to improve the ability of checkpoint inhibitors to kill cancer cells while protecting healthy tissue. The BRI Clinical Research Program works closely with oncologists at Virginia Mason to enroll subjects in this study. In a second project involving immunotherapy, BRI scientists collaborated to understand, predict and prevent insulin-dependent diabetes following checkpoint therapy for cancer. After treatment with checkpoint inhibitors, roughly 1 of cancer patients develop a kind of insulin-dependent diabetes that appears similar to type 1 diabetes. The goal of this collaborative research initiative was to better understand this phenomenon and to identify the causes of diabetes in these patients. The autoimmunity research collaborators also intended to shed light on the causes of T1D in the broader population.
Form 990, Part III, Line 4c continued5 Pursuing a Revolution in IBD Treatment - BRI researchers searched for biomarkers that could help make IBD treatment more precise and effective through a precision medicine approach that could tailor treatment to individual patients. They worked to identify biomarkers - proteins and other molecules in patients blood or cells - to predict response to a specific drug. The researchers started this study by taking blood samples from Virginia Mason IBD patients before they started using the drug vedolizumab, and then again after they had taken several doses, carefully analyzing the immune cells in these samples. Vedolizumab binds to a specific type of receptor on the outside of some immune cells, and the researchers discovered that some people who have more of this receptor respond better to the drug. 6 Aiming for Better Lupus Treatments - Immune cells protect us by hunting down bacteria and viruses, but a BRI team found that cells that lack a gene called ATG5 never stop attacking. Eventually, they aim at healthy cells and cause lupus. Scientists think it might be possible to stop these attacks by using medications to reactivate ATG5 and other genes, which could switch off overactive immune cells. A second research team identified a different gene involved in lupus BANK1. This gene plays a role in immune cells called B cells. Many B cells make tiny proteins called antibodies, and some of those antibodies attack healthy cells, causing lupus. The team showed that BANK1 may increase the number of B cells that make antibodies, especially in people with lupus who have a particular BANK1 variant. The work is helping us move toward better, more personalized treatments of lupus.
Form 990, Part III, Line 4c continuedThe Center for Interventional Immunology translates discoveries in the lab to patient therapies in the clinic through small and large-scale clinical studies. The Center for Interventional Immunology is also home to the Diabetes Clinical Research Program as well as the Clinical Research Program CRP, which provides compliance oversight of all interventional studies at BRI and Virginia Mason Medical Center. The CRP also manages all clinical research conducted by Virginia Mason Medical Center physicians and supports a number of specimen collection protocols developed within the Translational Immunology Center, particularly in cancer research. Details about CRP activities are provided below. Advancements in 2019 included the following 1 BRI leads the Type 1 Diabetes TrialNet, a National Institutes of Health-funded clinical trial network for type 1 diabetes prevention and early treatment, serving as the TrialNet hub of 28 clinical centers working with more than 200 screening and clinical research sites across the U.S. and six other countries. 2 An Immunotherapy Drug that can Delay T1D - A TrialNet prevention study involving diabetes researchers and volunteers at BRI showed a drug that targets the immune system - teplizumab - can delay type 1 diabetes a median of two years in children and adults at high risk. That is good news for relatives of people with type 1 diabetes, who are at 15 times greater risk of the disease than the general population. Samples collected during the trial are being studied to help researchers understand why certain people responded to the drug better than others, and next, researchers hope to conduct additional studies to look for ways to extend the benefits of the drug. 3 The TrialNet Pathway to Prevention study screened relatives of people with type 1 diabetes to find out if these family members are at risk for developing diabetes. Relatives of people with type 1 diabetes have about a three to four percent chance of testing positive for autoantibodies associated with diabetes. At-risk relatives are offered additional tests to estimate their chances of developing type 1 diabetes. Those who qualify have the opportunity to enroll in a prevention trial. All research volunteers are closely monitored for early detection of type 1 diabetes. Early detection of type 1 diabetes may improve blood sugar control and reduce the chances of complications. 4 Home to the JDRF Core for Clinical Assay Validation CAV, BRI plays an important role in identifying type 1 diabetes biomarkers and in helping outside researchers get the most accurate test results. The CAV is pinpointing key biomarkers, such as those indicating which patients will keep making insulin for years and which patients wont. The CAV also helps maintain quality control for a worldwide network of research labs by asking them to perform specific tests and reviewing their results. 5 The Center for systems Immunology analyzes large and complex data sets across all the other Centers, to identify patterns that accelerate discovery and disease breakthroughs. Advancements in 2019 included the following Identifying and helping T1D fast progressors - When some people are diagnosed with type 1 diabetes T1D, the disease progresses so quickly that their pancreas stops making insulin within a year. For others, the process is slower and their disease is easier to manage. BRI researchers revealed that it is possible to identify the fast progressors early and match them with treatments that help keep them healthy for longer. This research showed that slow progressors have higher levels of exhausted CD8 T cells - cells that are worn out from attacking the pancreas. The discovery could lead to a test that identifies how quickly individual patients will lose their ability to make insulin.
Form 990, Part III, Line 4dClinical Research Program Benaroya Research Institute oversees all clinical research at Virginia Mason Medical Center, which combines the expertise of BRI in management of interventional studies with the remarkable care of a quality healthcare leader. The BRI Clinical Research Program supports BRI and Virginia Mason clinical investigators in studies across a wide variety of autoimmune and immune-mediated diseases and conditions, as well as a broad range of other diseases such as cancer and cardiac disease. Each year the Clinical Research Program staff enrolls approximately 1500 study participants into Virginia Mason trials. This program involves approximately 150 research investigators at Virginia Mason Medical Center, and oversees more than 400 active studies with more than 275 studies currently open to enrollment. Teaming Up Against Celiac Disease - Researchers used tetramer technology pioneered by a BRI scientist and used to isolate particular immune cells to pinpoint attacker T cells in blood samples from patients with celiac disease. In these patients, only about three in 100,000 T cells react to gluten, sparking immune attacks that lead to the diseases debilitating symptoms. The researchers are working to figure out why these cells attack the body, perhaps leading them to diagnostic tools and therapies for patients with celiac symptoms - as well as their family members, because autoimmune disease can run in families. Testing a New MS Therapy - a research study at BRI and Virginia Mason seeks to find out if an experimental oral drug, similar to a currently available MS medication, would be just as effective as the current one, but with fewer gastrointestinal side effects. In an earlier study, half the research participants took this experimental drug and half took the current drug. Participants who finished the five-week study then enrolled in a two-year study of the experimental drug, under way in 2019.
Form 990, Part VI, Section A, Line 1aThe governing body delegates to an Executive Committee comprised of four officers of the Board and the Chairs of each standing Board Committee, the authority of the Board of Directors in the management of the corporation as may be deemed by the Executive Committee to be appropriate, to be exercised in time periods between regularly scheduled meetings of the Board of Directors provided that the Executive Committee has the authority to act only in time sensitive or emergency situations. The President and the Executive Director of the corporation serve as ex officio members of the Executive Committee without voting rights. The Executive Committee does not have the authority to amend, alter or repeal the bylaws elect, appoint or remove any member of such Executive Committee or any director or officer of the corporation amend the articles of incorporation adopt a plan of merger or adopt a plan of consolidation with another corporation authorize the sale, lease or exchange of all or substantially all of the property and assets of the corporation not in the ordinary course of business authorize the voluntary dissolution of the corporation or revoke proceedings therefore adopt a plan for the distribution of the assets of the corporation or amend, alter or repeal any resolution of the Board which by its terms provides that it shall not be amended, altered or repealed by such Executive Committee. The Executive Committee also serves as the planning committee for the Board of Directors and oversees any compliance issues raised by the Board of Directors.
Form 990, Part VI, Section A, Line 6,7Virginia Mason Health System VMHS is the sole corporate member of Benaroya Research Institute at Virginia Mason BRI. VMHS as the sole voting member has the following approval rights a election or appointment of Directors and Officers of the Board of Directors b removal of Directors and Officers of the Board of Directors including any executive officer of the corporation c approval of all long-range and short-range plans proposed by the Board of Directors d approval of the annual capital and operating budgets proposed by the Board of Directors e approval of the borrowing of funds where the amount borrowed is in excess of Five Hundred Thousand Dollars 500,000 f approval of the sale, lease, exchange, mortgage, pledge or disposal of all or substantially all of the property and assets g approval of all amendments to or repeal of the Agreement Association or the Bylaws of the corporation h all other rights and powers as specified in the Washington Nonprofit Corporation Act.
Form 990, Part VI, Section B, Line 11bThe VMHS Audit and Compliance Committee ACC, a committee composed of independent community members has been delegated responsibility for oversight of the annual Form 990 preparation process including a selection, engagement, and review of the performance of the independent tax preparer b review of the annual draft Form 990 tax return, and c recommendation of the final Form 990 tax return for review to the BRI Board of Directors. Annually, at the September meeting, management and the tax preparer provide the ACC with an initial draft of the Form 990 and present an overview of the Form 990 preparation process. The final Form 990 is reviewed by the ACC in November followed by a Board review of the final Form 990 prior to filing. The final Form 990 tax return is provided to each member of the Board of Directors via electronic delivery.
Form 990, Part VI, Section B, Line 12cThe VMHS Governance Committee has been delegated accountability for oversight of the process for disclosure, evaluation and management of conflict of interest involving any member of the BRI Board of Directors, executive leadership or key employees Covered Person. Pursuant to the Conflict of Interest Policy, an annual conflict of interest questionnaire is distributed to all Covered Persons. In addition, a Covered Person has an on-going duty to disclose the existence of a conflict of interest at any time an actual or potential conflict arises. Each Covered Person is required upon appointment and annually thereafter to attest to a statement that affirms that such person has a received a copy of the Conflict of Interest Policy b has read and understands the Policy c has agreed to comply with the Policy and d understands that BRI is a charitable organization and that in order to maintain its federal tax exemption must engage in activities that accomplish its tax-exempt purposes. Written disclosures are reviewed by the Governance Committee to determine if an actual or potential conflict of interest exists and if so, how it should be managed. The Covered Person is informed in writing regarding the determination the Conflict of Interest Management Plan. No Covered Person with an actual or potential conflict of interest shall engage in an activity on BRIs behalf related to the disclosed actual or potential Conflict of Interest unless such activity is permitted by the Conflict of Interest Management Plan or until the Covered Person has undertaken all steps set forth in the Management Plan to manage, reduce or eliminate the conflict. All Covered Persons have a duty to disclose the existence of any actual or potential conflict of interest with respect to meeting agenda items. The Conflict of Interest Policy requires that copies of the Conflict of Interest Questionnaire be completed annually by each covered Person and any Conflict of Interest Management Plan be maintained.
Form 990, Part VI, Section B, Line 15The VMHS Compensation and Benefits Board Committee, a committee composed solely of independent directors none of whom have a conflict of interest, is accountable for setting reasonable total compensation packages for each executive, officer and key employee Executive consistent with BRIs compensation philosophy and principles. The Committee approves annual goals and performance criteria which are used in determining merit increases and variable compensation opportunities. The Committee assesses performance against these goals. The Committee selects and engages a qualified independent compensation consultant to review and analyze the total compensation and benefits packages of the Executives. The Committee as part of its analysis obtains from the compensation consultant appropriate comparability data including total compensation paid by similarly situated organizations for positions that are functionally comparable to each of the Executives. The Committee will consider the significant terms of the agreement with each Executive including the total compensation to be paid and the employees duties and responsibilities. Consistent with the compensation philosophy and principles, the Committee approves total compensation packages for each of the Executives based on information presented to the Committee, reasonableness and the best interest of BRI. The Committees decisions regarding compensation for each Executive are documented in written resolutions and minutes of the Committee. The Committee promptly reports its actions to the VMHS board which reports are reflected in the Boards minutes. The individual positions who were reviewed in 2019 were Jane Buckner, BRI President and Director, Carla Greenbaum, BRI Director, Margaret McCormick, Executive Director and Chief Operating Officer, and Michael Labosier, Chief Financial Officer.
Form 990, Part VI, Section C, Line 19The organizations Articles, Bylaws, Conflict of Interest Policy and financial statements are made available upon request.

Schedule R IRS990ScheduleR

Id Related Tax Exempt Org IdRelatedTaxExemptOrgGrp (4 entries)

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Virginia Mason Medical Center
1100 Ninth AvenueSeattleWA98101910565539Health CareWASec 501c33falseVMHS
Virginia Mason Institute
1100 Ninth AvenueSeattleWA98101263763656EducationWASec 501c39falseVMMC
Yakima Valley Memorial Hospital Association
2811 Tieton DriveYakimaWA98902910567263Health CareWASec 501c33falseVMHS
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Affiliated Group Schedule AffiliatedGroupSchedule

Affiliated Schedule AffiliatedScheduleGrp (5 entries)

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Benaroya Research Institute at Virginia Mason
1200 Ninth AvenueSeattleWA98101910653422$0$0$0$71,446,676$71,446,676$40,449$10,112$0$0$0
Virginia Mason Medical Center
1100 Ninth AvenueSeattleWA98101910565539$134,909$63,581$198,490$1,174,521,397$1,174,719,887$665,053$166,263$0$0$0Yes (X)
Virginia Mason Institute
1100 Ninth AvenueSeattleWA98101263763656$0$0$0$6,260,831$6,260,831$3,544$886$0$0$0
Virginia Mason Health System
1100 Ninth AvenueSeattleWA98101911351110$0$0$0$14,136,817$14,136,817$8,003$2,001$0$0$0
Yakima Valley Memorial Hospital Association
2811 Tieton DriveYakimaWA98902910567263$48,610$60,000$108,610$499,682,326$499,790,936$282,950$70,738$0$0$0