HOWARD HUGHES MEDICAL INSTITUTE: Form 990, tax year 2015

View the entire original 990 at ProPublica ↗

Organization: HOWARD HUGHES MEDICAL INSTITUTE (EIN 59-0735717)
Tax period: 2015-09-01 to 2016-08-31
Filed: 2017-04-19
IRS object ID: 201721099349300802
Schema version: 2015v3.0
Source: Download XML · Original 990 at ProPublica

Every field in the e-filed return. Faint text is the IRS element name, for citing.

Return header
Form 990
Schedule A
Schedule B
Schedule C
Schedule D
Schedule F
Schedule I
Schedule J
Schedule K
Schedule K
Schedule O
Schedule R

Return header ReturnHeader

Field	Value	IRS element (for citing)
Return	2017-04-19T09:00:10-05:00	ReturnTs
Tax Period End	2016-08-31	TaxPeriodEndDt

Preparer Firm PreparerFirmGrp

Field	Value	IRS element (for citing)
Preparer Firm EIN	134008324	PreparerFirmEIN

Preparer Firm Name PreparerFirmName

Field	Value	IRS element (for citing)
Business Name Line1	PRICEWATERHOUSECOOPERS LLP	BusinessNameLine1Txt

Preparer US Address PreparerUSAddress

Field	Value	IRS element (for citing)
Address Line1	600 13TH STREET NW STE 1000	AddressLine1Txt
City	WASHINGTON	CityNm
State Abbreviation	DC	StateAbbreviationCd
ZIP	20005	ZIPCd

Field	Value	IRS element (for citing)
Return Type	990	ReturnTypeCd
Tax Period Begin	2015-09-01	TaxPeriodBeginDt

Filer Filer

Field	Value	IRS element (for citing)
EIN	590735717	EIN

Business Name BusinessName

Field	Value	IRS element (for citing)
Business Name Line1	Howard Hughes Medical Institute	BusinessNameLine1Txt

Field	Value	IRS element (for citing)
Business Name Control	HOWA	BusinessNameControlTxt
Phone	3012158500	PhoneNum

US Address USAddress

Field	Value	IRS element (for citing)
Address Line1	4000 JONES BRIDGE ROAD	AddressLine1Txt
City	CHEVY CHASE	CityNm
State Abbreviation	MD	StateAbbreviationCd
ZIP	20815	ZIPCd

Business Officer BusinessOfficerGrp

Field	Value	IRS element (for citing)
Person	Nitin V Kotak	PersonNm
Person Title	CFO & Treasurer	PersonTitleTxt
Signature	2017-04-19	SignatureDt
Discuss With Paid Preparer	Yes (true)	DiscussWithPaidPreparerInd

Preparer Person PreparerPersonGrp

Field	Value	IRS element (for citing)
Preparer Person	Marci Krause	PreparerPersonNm
PTIN	P00394681	PTIN
Phone	2024141000	PhoneNum

Field	Value	IRS element (for citing)
Tax	2015	TaxYr
Build TS	2021-01-29 14:40:06Z	BuildTS

Form 990 IRS990

Principal Ofcr Business Name PrincipalOfcrBusinessName

Field	Value	IRS element (for citing)
Business Name Line1	ERIN K O'SHEA PHD	BusinessNameLine1Txt

US Address USAddress

Field	Value	IRS element (for citing)
Address Line1	4000 JONES BRIDGE ROAD	AddressLine1Txt
City	CHEVY CHASE	CityNm
State Abbreviation	MD	StateAbbreviationCd
ZIP	20815	ZIPCd

Field	Value	IRS element (for citing)
Gross Receipts	$60,901,814,102	GrossReceiptsAmt
Group Return For Affiliates	false	GroupReturnForAffiliatesInd
Organization501c3	Yes (X)	Organization501c3Ind
Website Address	WWW.HHMI.ORG	WebsiteAddressTxt
Type Of Organization Corp	Yes (X)	TypeOfOrganizationCorpInd
Formation	1953	FormationYr
Legal Domicile State	DE	LegalDomicileStateCd
Activity Or Mission	THE HOWARD HUGHES MEDICAL INSTITUTE IS A PHILANTHROPY THAT SERVES SOCIETY THROUGH THE DIRECT CONDUCT OF BIOMEDICAL RESEARCH AND SUPPORT FOR PROGRAMS IN SCIENCE EDUCATION.	ActivityOrMissionDesc
Voting Members Governing Body	10	VotingMembersGoverningBodyCnt
Voting Members Independent	10	VotingMembersIndependentCnt
Total Employee	3383	TotalEmployeeCnt
Total Volunteers	0	TotalVolunteersCnt
Total Gross UBI	-$1,833,057	TotalGrossUBIAmt
Net Unrelated Bus Txbl Incm	$0	NetUnrelatedBusTxblIncmAmt
PY Contributions Grants	$66,401	PYContributionsGrantsAmt
CY Contributions Grants	$19,321,241	CYContributionsGrantsAmt
PY Program Service Revenue	$2,033,219	PYProgramServiceRevenueAmt
CY Program Service Revenue	$2,223,162	CYProgramServiceRevenueAmt
PY Investment Income	$1,963,222,595	PYInvestmentIncomeAmt
CY Investment Income	$921,724,327	CYInvestmentIncomeAmt
PY Other Revenue	$17,244,324	PYOtherRevenueAmt
CY Other Revenue	$257,052,143	CYOtherRevenueAmt
PY Total Revenue	$1,982,566,539	PYTotalRevenueAmt
CY Total Revenue	$1,200,320,873	CYTotalRevenueAmt
PY Grants And Similar Paid	$46,910,392	PYGrantsAndSimilarPaidAmt
CY Grants And Similar Paid	$138,793,048	CYGrantsAndSimilarPaidAmt
CY Benefits Paid To Members	$0	CYBenefitsPaidToMembersAmt
PY Salaries Comp Emp Bnft Paid	$422,462,257	PYSalariesCompEmpBnftPaidAmt
CY Salaries Comp Emp Bnft Paid	$438,554,171	CYSalariesCompEmpBnftPaidAmt
CY Total Prof Fndrsng Expns	$0	CYTotalProfFndrsngExpnsAmt
CY Total Fundraising Expense	$0	CYTotalFundraisingExpenseAmt
PY Other Expenses	$544,226,576	PYOtherExpensesAmt
CY Other Expenses	$556,129,969	CYOtherExpensesAmt
PY Total Expenses	$1,013,599,225	PYTotalExpensesAmt
CY Total Expenses	$1,133,477,188	CYTotalExpensesAmt
PY Revenues Less Expenses	$968,967,314	PYRevenuesLessExpensesAmt
CY Revenues Less Expenses	$66,843,685	CYRevenuesLessExpensesAmt
Total Assets BOY	$21,693,736,438	TotalAssetsBOYAmt
Total Assets EOY	$21,082,502,290	TotalAssetsEOYAmt
Total Liabilities BOY	$3,522,501,322	TotalLiabilitiesBOYAmt
Total Liabilities EOY	$3,306,942,737	TotalLiabilitiesEOYAmt
Net Assets Or Fund Balances BOY	$18,171,235,116	NetAssetsOrFundBalancesBOYAmt
Net Assets Or Fund Balances EOY	$17,775,559,553	NetAssetsOrFundBalancesEOYAmt
Mission	THE HOWARD HUGHES MEDICAL INSTITUTE ("INSTITUTE" OR "HHMI") IS THE NATION'S LARGEST PRIVATE BIOMEDICAL RESEARCH INSTITUTION, WITH JUST UNDER $18 BILLION IN NET ASSETS AT THE END OF ITS 2016 FISCAL YEAR. THE MISSION OF THE INSTITUTE HAS REMAINED CONSTANT SINCE ITS FOUNDING IN 1953. AS ITS CHARTER STATES "THE PRIMARY PURPOSE AND OBJECTIVE OF THE HOWARD HUGHES MEDICAL INSTITUTE SHALL BE THE PROMOTION OF HUMAN KNOWLEDGE WITHIN THE FIELD OF BASIC SCIENCES (PRINCIPALLY THE FIELD OF MEDICAL RESEARCH AND EDUCATION) AND THE EFFECTIVE APPLICATION THEREOF FOR THE BENEFIT OF MANKIND."	MissionDesc
Significant New Program Srvc	false	SignificantNewProgramSrvcInd
Significant Change	false	SignificantChangeInd
Expense	$711,129,790	ExpenseAmt
Grant	$0	GrantAmt
Revenue	$2,169,244	RevenueAmt
Desc	MEDICAL RESEARCH ORGANIZATION ACTIVITIES (A) THE HHMI INVESTIGATOR PROGRAM (B) JANELIA RESEARCH CAMPUS (C) HIGHLIGHTS FROM HHMI RESEARCH LABORATORIES (FISCAL YEAR 2016) (D) HONORS AND AWARDS RECEIVED BY HHMI SCIENTISTS (A) THE HHMI INVESTIGATOR PROGRAM THE HOWARD HUGHES MEDICAL INSTITUTE'S APPROACH TO BIOMEDICAL RESEARCH CAN BE SUMMARIZED IN THREE WORDS: PEOPLE, NOT PROJECTS. BY EMPLOYING SCIENTISTS AS HHMI INVESTIGATORS - RATHER THAN AWARDING RESEARCH GRANTS - THE INSTITUTE PROVIDES LONG-TERM, FLEXIBLE FUNDING THAT ENABLES ITS RESEARCHERS TO PURSUE THEIR SCIENTIFIC INTERESTS WHEREVER THEY LEAD. HHMI BELIEVES THAT SCIENTISTS OF EXCEPTIONAL TALENT AND IMAGINATION WILL MAKE FUNDAMENTAL DISCOVERIES OF LASTING SCIENTIFIC VALUE AND BENEFIT TO HUMANITY IF THEY ARE GIVEN THE RESOURCES, TIME, AND FREEDOM TO PURSUE CHALLENGING QUESTIONS. THE INSTITUTE NURTURES THE CREATIVITY AND INTELLECTUAL DARING OF SCIENTISTS WHO ARE WILLING TO SET ASIDE CONVENTIONAL WISDOM OR THE "EASY" QUESTION FOR A FUNDAMENTAL PROBLEM THAT MAY TAKE MANY YEARS TO SOLVE. AMONG THE CHARACTERISTICS THAT DISTINGUISH THIS GROUP OF SCIENTISTS ARE QUALITIES SUCH AS CREATIVITY, A PENCHANT FOR RISK-TAKING, AND A COMMITMENT TO DISCOVERY, PRODUCTIVITY, AND PERSEVERANCE. THIS UNIQUE RESEARCH MODEL IS AN IMAGINATIVE AND POWERFUL ALTERNATIVE TO FUNDING BIOMEDICAL RESEARCH THROUGH GRANTS. THE HHMI INVESTIGATOR PROGRAM EMPLOYS MORE THAN 300 HHMI INVESTIGATORS, AMONG THEM 17 NOBEL LAUREATES AND 192 MEMBERS OF THE NATIONAL ACADEMY OF SCIENCES. HHMI INVESTIGATORS DIRECT INSTITUTE RESEARCH LABORATORIES ON THE CAMPUSES OF 65 UNIVERSITIES AND OTHER RESEARCH ORGANIZATIONS THROUGHOUT THE UNITED STATES. SINCE THE EARLY 1990S, INVESTIGATORS HAVE BEEN SELECTED THROUGH RIGOROUS NATIONAL COMPETITIONS. THE INSTITUTE SOLICITS APPLICATIONS DIRECTLY FROM SCIENTISTS AT MEDICAL SCHOOLS AND OTHER RESEARCH INSTITUTIONS IN THE UNITED STATES, WITH THE AIM OF IDENTIFYING THOSE WHO HAVE THE POTENTIAL TO MAKE SIGNIFICANT CONTRIBUTIONS TO SCIENCE. HHMI EMPLOYS AN OPEN APPLICATION PROCESS TO ENSURE THAT IT IS SELECTING ITS RESEARCHERS FROM A BROAD AND DEEP POOL OF SCIENTIFIC TALENT. In October 2015, the Royal Swedish Academy of Sciences selected Paul Modrich, an HHMI investigator at Duke University, together with Tomas Lindahl of the Francis Crick Institute and Clare Hall Laboratory in the UK and Aziz Sancar of University of North Carolina, Chapel Hill, as recipients of the 2015 Nobel Prize in Chemistry for mechanistic studies of DNA repair. The trio was honored for mapping, at a molecular level, how cells repair damaged DNA and safeguard the genetic information. According to the Nobel Foundation, their work has provided fundamental knowledge of how a living cell functions and is, for instance, used for the development of new cancer treatments. In June 2016, the HHMI Trustees elected David E. Clapham, MD, PhD, an HHMI investigator at Boston Children's Hospital, as Vice President and Chief Scientific Officer. Clapham was the Aldo R. Castaneda Professor of Cardiovascular Research at Children's Hospital Boston and Professor of Neurobiology and Pediatrics at Harvard Medical School. A member of both the National Academy of Sciences and the American Academy of Arts and Sciences, he is a leader in the field of ion channel research. His research focuses on the role of calcium as an intracellular messenger and on the signals that control ion channels that carry calcium between cells. The identification and characterization of ion channels may make it possible to develop drugs that alleviate many disorders. Clapham succeeds Erin O'Shea, PhD, who was named president of HHMI . In HHMI launched the Transformative Technology Program that allows HHMI Investigators to acquire cutting-edge research equipment for their institution that simultaneously benefits their HHMI and non-HHMI colleagues. Through cost sharing with host institutions, the Transformative Technology Program provides a path by which HHMI scientists and colleagues can obtain research equipment that's typically difficult to fund. In general, this program will purchase and own the major equipment items, while the host institution's cost-sharing funds will support the ongoing setup and operation of the core facilities that house the instruments. In this initial competition, HHMI invested a total of $18.8 million for six projects that will benefit researchers around the country. This year, HHMI, the Simons Foundation, and the Bill & Melinda Gates Foundation selected 84 Faculty Scholars, early-career scientists who have great potential to make unique contributions to their field. The scientists represent 43 institutions across the United States. Through the new Faculty Scholars Program, the philanthropies will spend about $83 million over five years to support the first cohort of scientists selected to receive grants. The range of five-year grant award totals is $600,000-$1.8 million, including indirect costs. Faculty Scholars are required to devote at least 50 percent of their total effort to the direct conduct of research. Highlights of research conducted, and awards received, by HHMI scientists during its year ended August 31, 2016 are included below. (B) Janelia Research Campus The Janelia Research Campus offers a collaborative research environment for scientists across an array of disciplines who have focused on two broad scientific areas of scientific inquiry: the identification of general principles governing how neuronal circuits process information and development of imaging technologies and computational methods that support image analysis. In the current fiscal year, there were 47 group leaders at Janelia, in addition to graduate students, other scientific trainees, and visiting scientists. Janelia also operates a vibrant scientific conference program, bringing many scientists to its campus each year for educational meetings . In 2016, Janelia expanded its research program by launching a Neuronal Cell Biology Program that will support scientists investigating the structural and functional details of discrete neurons and exploring the inner landscape of these cells in dynamic neural environments, and leverage existing research and tools created at Janelia, such as the lattice light sheet microscope. The program will be led by Jennifer Lippincott-Schwartz, who moved to Janelia after 23 years as chief of the section on organelle biology in the Cell Biology and Metabolism Program, in the Division of Intramural Research at the National Institutes of Health (NIH).	Desc

Prog Srvc Accom Acty2 ProgSrvcAccomActy2Grp

Field	Value	IRS element (for citing)
Expense	$147,854,974	ExpenseAmt
Grant	$117,992,048	GrantAmt
Revenue	$53,918	RevenueAmt
Desc	SCIENCE EDUCATION PROGRAMS (A) GRADUATE SCIENCE EDUCATION AND MEDICAL RESEARCH TRAINING (B) PRECOLLEGE AND UNDERGRADUATE SCIENCE EDUCATION PROGRAM (C) EDUCATIONAL MEDIA (D) TANGLED BANK STUDIOS (E) ELIFE - OPEN ACCESS JOURNAL HHMI'S DEPARTMENT OF SCIENCE EDUCATION EMPHASIZES INITIATIVES WITH THE POWER TO TRANSFORM GRADUATE, UNDERGRADUATE, AND PRECOLLEGE EDUCATION IN THE LIFE SCIENCES. HHMI IS THE LARGEST PRIVATE FUNDER OF SCIENCE EDUCATION IN THE UNITED STATES. DURING THE FISCAL YEAR, THE INSTITUTE DISTRIBUTED $57 MILLION IN GRANTS TO SUPPORT SCIENCE EDUCATION. The Institute's science education programs support ties between scientific research and teaching with the goal of increasing and enhancing student research opportunities; improving science courses, curricula, and instruction; and providing enhanced graduate and medical training opportunities. Most HHMI grants are awarded through competitions with specific objectives and eligibility criteria and awards are generally made following a stringent process of peer review. HHMI's educational activities are funded through three major programs; the goals of each program and the major activities for the year are summarized below. (A) Graduate Science Education and Medical Research Training These programs focus on the development of innovative graduate education through grants to institutions and fellowships to students. They support research fellowships for medical students, doctoral fellowships for students who are committed to increasing diversity among scientists, doctoral fellowships for international students pursuing the PhD at U.S. institutions. This fiscal year, HHMI selected 66 medical and veterinary students to participate in the Medical Research Fellows Program. The fellowships enable students to take a year off from professional school to conduct laboratory research. The hope is that these students will one day choose to work at the crossroads of basic research and clinical medicine. Six fellows in this year's class of 66 initial awardees are supported by HHMI's funding partners: Burroughs Wellcome Fund (BWF), Citizens United for Research in Epilepsy (CURE), the Duchenne Research Fund (DRF), and the Society of Interventional Radiology Foundation (SIRF). The program has funded more than 1,700 students since its start in 1989. This year, 13 fellows from the 2015 class are supported by HHMI for an additional year, making it the largest class of second-year fellows in the program's history. The program usually averages six second-year fellows per year. The International Predoctoral Fellowship program identifies accomplished and promising graduate students whose home countries are outside of the United States and who are ineligible for U.S. federal training grant support. Each fellowship is for three years, and pays a stipend, institutional allowance, and research allowance totaling $43,000 per year. In fiscal year 2016, HHMI selected 20 graduate students as International Predoctoral Fellows. HHMI's Gilliam Fellowships for Advanced Study Program awarded 34 fellowships to outstanding students who are pursuing a PhD in the life sciences and who are committed to increasing diversity among scientists. Each fellow will receive an annual award totaling $46,000, which includes a stipend, a training allowance, and an allowance for each fellow's institution, for up to three years. The applicant pool for the Gilliam fellowships consists of graduate students nominated by the principal investigators of non-MSTP T32 training grants awarded through the National Institute of General Medical Sciences (NIGMS), and alumni of HHMI's Exceptional Research Opportunities Program (EXROP), an initiative that provides undergraduate minority students with the opportunity to conduct research under the mentorship of HHMI scientists. A total of 142 students applied for the fellowships this year, including 18 EXROP alumni. (B) Precollege and Undergraduate Science Education Program These programs recruit and develop the future leaders of science and enhance science literacy among all students. Precollege grants support teacher training and inquiry-based student learning. Grants to colleges and universities support undergraduate student research, faculty and curriculum development, and science education outreach activities. In the 2016 fiscal year: HHMI has invited 91 schools to submit full proposals to apply for grants through HHMI's $60 million Inclusive Excellence initiative that is encouraging colleges and universities to broaden access to science excellence for all students. The proposals will be considered for first-round awards that will begin in September 2017. HHMI plans to award approximately 60 grants in two rounds of open competitions, each of which will follow the same format. In this round of the competition, HHMI will award up to 30 grants to institutions that are committed to inclusive science education and are well positioned to work over the next five years to improve their ability to become more inclusive of all students. HHMI's long-term aim is for successful strategies pioneered by the grantee institutions to serve as models to be adapted and adopted by other institutions. The 91 schools were selected from 511 that submitted pre-proposals in response to HHMI's launch of the initiative in May 2015. HHMI continued its partnership with the University of Maryland, Baltimore County (UMBC), the Pennsylvania State University, and the University of North Carolina at Chapel Hill (UNC), to launch the collaborative Meyerhoff Adaptation Project. The project aims to learn whether elements of UMBC's highly regarded Meyerhoff Scholars Program can be adapted at Penn State and UNC. The participating schools hope to share what they learn so other institutions might follow. During the five-year Meyerhoff Adaptation Project, Penn State and UNC, working closely with UMBC and HHMI, will expand and study the Meyerhoff model, while applying it to newly created programs on their campuses. The HHMI Professors Program empowers research scientists who can convey the excitement of science to undergraduates. The professors model fundamental reform in the way undergraduate science is taught at research universities through innovative teaching that demonstrates the rigor and value of scientific research. HHMI professors are committed to expanding and enhancing research opportunities for undergraduates and are encouraged to share ideas and collaborate with their peers to improve science education. Fifty-five scientists have been named HHMI professors since the program began in 2002. In addition to their commitment to student learning, these highly visible scientists have developed new educational resources and implemented novel mentoring programs to support students. In April 2016, HHMI announced a competition to select up to 15 new HHMI professors who will each receive a five-year, nonrenewable grant totaling $1 million; these awards will be made in the fall of 2017. The HHMI's Exceptional Research Opportunities Program (EXROP) is designed to encourage talented students to pursue careers in science by placing selected undergraduates in summer research experiences in the labs of HHMI investigators, professors, and at the Janelia Research Campus. In 2016, a total of 102 college students (69 first-year students and 33 second-year, "EXROP Capstone" students) were selected to participate in EXROP. The 2016 cohort marked the 14th year of the program.	Desc

Prog Srvc Accom Acty3 ProgSrvcAccomActy3Grp

Field	Value	IRS element (for citing)
Expense	$20,914,932	ExpenseAmt
Grant	$20,801,000	GrantAmt
Revenue	$0	RevenueAmt
Desc	SUPPORT FOR INTERNATIONAL SCIENCE (A) NEW INTERNATIONAL RESEARCH SCHOLARS PROGRAM (B) SENIOR INTERNATIONAL RESEARCH SCHOLARS PROGRAM (C) INTERNATIONAL EARLY CAREER SCIENTIST PROGRAM (D) AFRICA HEALTH RESEARCH INSTITUTE LAUNCHES IN SOUTH AFRICA (A) New International Research Scholars Program HHMI, together with the Bill & Melinda Gates Foundation, the Wellcome Trust, and the Calouste Gulbenkian Foundation, announced an international program to provide research support for up to 40 outstanding early career scientists. The program's aim is to help develop scientific talent worldwide in a wide variety of biomedical research fields. Awardees will be notified in April 2017. HHMI and its partners have committed a total of $30 million for the International Research Scholars Program and will award each scientist who is selected a total of $650,000 over five years. The competition is open to scientists who have trained in the U.S. or United Kingdom for at least one year and who have run their own labs for less than seven years. (B) Senior International Research Scholars Program HHMI continues to support 13 of the world's leading basic science researchers as Senior International Research Scholar (SIRS). The awards support outstanding biomedical scientists working outside the United States who have made significant contributions to fundamental research in the biological sciences. The SIRS awardees, selected from a group of previous HHMI international research scholars, are respected leaders in their fields. Each HHMI senior international research scholar receives a grant of $100,000 per year over five years, and presents their research at scientific meetings held at HHMI. The gatherings are intended to facilitate the exchange of ideas, stimulate new research, and provide an opportunity for collaboration with other HHMI scientists. The senior international research scholars' participation helps strengthen the growing network of international biomedical researchers. (C) International Early Career Scientist Program HHMI continues to support 24 international early career scientists who were selected for awards in 2012. Each selected scientist will receive $650,000 over a period of five years with the goal of helping these talented individuals establish independent research programs. In this pilot program, HHMI identified scientists who are, or have the potential to become, scientific leaders. The 24 HHMI international early career scientists conduct research at 20 institutions in 12 countries. Each scientist who was selected had directed his or her own laboratory for less than seven years when they applied to HHMI. The countries represented by the HHMI international early career scientists are Argentina, Brazil, Chile, China, Hungary, India, Italy, Poland, Portugal, South Africa, Spain, and South Korea. (D) Africa Health Research Institute Launches in South Africa In 2009, HHMI helped launch the KwaZulu-Natal Research Institute for TB-HIV (K-RITH) in collaboration with the University of KwaZulu-Natal (UKZN), and has provided significant funding to support its research efforts. In 2016, in a move to improve the health of people locally and globally, K-RITH joined forces with the Africa Centre for Population Health to form a groundbreaking new interdisciplinary institute to fight tuberculosis (TB), HIV and related diseases. The new organization, the Africa Health Research Institute, is located at the heart of South Africa's TB and HIV co-epidemic in KwaZulu-Natal Province. The effort brings together the Africa Centre's detailed population data from over 100,000 participants, with K-RITH's expertise in basic science and its world-class laboratory facilities. The new venture is made possible through grants from HHMI and Wellcome Trust, with the University College London and UKZN as significant academic partners. The Africa Health Research Institute is committed to working towards the elimination of HIV and TB. To achieve this, the institute will bring together leading researchers from different fields, use cutting-edge science to improve people's health, and will help to train the next generation of African scientists.	Desc

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Rcv Fnds To Pay Prsnl Bnft Cntrct	false	RcvFndsToPayPrsnlBnftCntrctInd
Pay Premiums Prsnl Bnft Cntrct	false	PayPremiumsPrsnlBnftCntrctInd
Indoor Tanning Services	false	IndoorTanningServicesInd
Info In Schedule O Part VI	Yes (X)	InfoInScheduleOPartVIInd
Governing Body Voting Members	10	GoverningBodyVotingMembersCnt
Independent Voting Member	10	IndependentVotingMemberCnt
Family Or Business Rln	false	FamilyOrBusinessRlnInd
Delegation Of Mgmt Duties	false	DelegationOfMgmtDutiesInd
Change To Org Documents	false	ChangeToOrgDocumentsInd
Material Diversion Or Misuse	false	MaterialDiversionOrMisuseInd
Members Or Stockholders	false	MembersOrStockholdersInd
Election Of Board Members	false	ElectionOfBoardMembersInd
Decisions Subject To Approva	false	DecisionsSubjectToApprovaInd
Minutes Of Governing Body	Yes (true)	MinutesOfGoverningBodyInd
Minutes Of Committees	Yes (true)	MinutesOfCommitteesInd
Officer Mailing Address	false	OfficerMailingAddressInd
Local Chapters	false	LocalChaptersInd
Form990 Provided To Gvrn Body	Yes (true)	Form990ProvidedToGvrnBodyInd
Conflict Of Interest Policy	Yes (true)	ConflictOfInterestPolicyInd
Annual Disclosure Covered Prsn	Yes (true)	AnnualDisclosureCoveredPrsnInd
Regular Monitoring Enfrc	Yes (true)	RegularMonitoringEnfrcInd
Whistleblower Policy	Yes (true)	WhistleblowerPolicyInd
Document Retention Policy	Yes (true)	DocumentRetentionPolicyInd
Compensation Process CEO	Yes (true)	CompensationProcessCEOInd
Compensation Process Other	Yes (true)	CompensationProcessOtherInd
Investment In Joint Venture	false	InvestmentInJointVentureInd
States Where Copy Of Return Is Fld	AK	StatesWhereCopyOfReturnIsFldCd
States Where Copy Of Return Is Fld	AZ	StatesWhereCopyOfReturnIsFldCd
States Where Copy Of Return Is Fld	CA	StatesWhereCopyOfReturnIsFldCd
States Where Copy Of Return Is Fld	IL	StatesWhereCopyOfReturnIsFldCd
States Where Copy Of Return Is Fld	MD	StatesWhereCopyOfReturnIsFldCd
States Where Copy Of Return Is Fld	MA	StatesWhereCopyOfReturnIsFldCd
States Where Copy Of Return Is Fld	NY	StatesWhereCopyOfReturnIsFldCd
States Where Copy Of Return Is Fld	OK	StatesWhereCopyOfReturnIsFldCd
States Where Copy Of Return Is Fld	OR	StatesWhereCopyOfReturnIsFldCd
States Where Copy Of Return Is Fld	IN	StatesWhereCopyOfReturnIsFldCd
Upon Request	Yes (X)	UponRequestInd

Books In Care Of Detail BooksInCareOfDetail

Business Name BusinessName

Field	Value	IRS element (for citing)
Business Name Line1	NITIN V KOTAK	BusinessNameLine1Txt

Field	Value	IRS element (for citing)
Phone	3012158500	PhoneNum

US Address USAddress

Field	Value	IRS element (for citing)
Address Line1	4000 JONES BRIDGE ROAD	AddressLine1Txt
City	CHEVY CHASE	CityNm
State Abbreviation	MD	StateAbbreviationCd
ZIP	20815	ZIPCd

Form990 Part VII Section A Form990PartVIISectionAGrp (35 entries)

TitleTitleTxt	Average Hours Per WeekAverageHoursPerWeekRt	Individual Trustee Or DirectorIndividualTrusteeOrDirectorInd	Reportable Comp From OrgReportableCompFromOrgAmt	Reportable Comp From Rltd OrgReportableCompFromRltdOrgAmt	Other CompensationOtherCompensationAmt	OfficerOfficerInd	Key EmployeeKeyEmployeeInd	Highest Compensated EmployeeHighestCompensatedEmployeeInd	Former Ofcr Director TrusteeFormerOfcrDirectorTrusteeInd
JAMES A BAKER III ESQ
TRUSTEE	2.0	Yes (X)	$40,000	$0	$0
CHARLENE BARSHEFSKY ESQ
TRUSTEE	2.0	Yes (X)	$40,000	$0	$0
JOSEPH L GOLDSTEIN MD
TRUSTEE, CHAIRMAN RESEARCH COMM	4.0	Yes (X)	$56,000	$0	$0
GARNETT L KEITH
TRUSTEE, CHAIRMAN FINANCE COMM until 2/16	4.0	Yes (X)	$50,000	$0	$0
FRED R LUMMIS
TRUSTEE, CHAIRMAN FINANCE COMM starting 2/16	4.0	Yes (X)	$40,000	$0	$0
PAUL M NURSE PHD
TRUSTEE	2.0	Yes (X)	$46,000	$0	$0
ALISON F RICHARD PHD
TRUSTEE, CHAIRMAN EDUCATION COMM	2.0	Yes (X)	$50,000	$0	$0
CLAYTON S ROSE PHD
TRUSTEE, CHAIRMAN AUDIT & COMP	6.0	Yes (X)	$50,000	$0	$0
KURT L SCHMOKE ESQ
TRUSTEE, CHAIRMAN	6.0	Yes (X)	$60,000	$0	$0
DEBORAH L SPAR PHD
TRUSTEE	2.0	Yes (X)	$0	$0	$0
ANNE M TATLOCK
TRUSTEE	2.0	Yes (X)	$40,000	$0	$0
LANDIS ZIMMERMAN
VP & CHIEF INVESTMENT OFFICER	40.0		$3,611,224	$0	$56,631	Yes (X)
LAUREN T SPILIOTES ESQ
DEP GENCOUNSEL/ASST SEC	40.0		$382,251	$0	$49,552	Yes (X)
SUSAN S PLOTNICK
ASSISTANT TREASURER & DIRECTOR-FINANCE	40.0		$235,740	$0	$55,201	Yes (X)
MONIQUE L MARCUS
CONTROLLER	40.0		$183,211	$0	$45,647	Yes (X)
ROBERT TJIAN PHD
PRESIDENT	40.0		$1,364,377	$0	$72,244	Yes (X)
CHERYL A MOORE
EXECUTIVE VP & COO	40.0		$891,077	$0	$47,771	Yes (X)
SEAN B CARROLL PHD
VP FOR SCIENCE EDUCATION	40.0		$690,554	$0	$53,014	Yes (X)
HEIDI E HENNING ESQ
VP,GENERAL COUNSEL/SEC	40.0		$565,186	$0	$54,742	Yes (X)
NITIN V KOTAK
VP, CFO & TREASURER	40.0		$406,965	$0	$57,153	Yes (X)
ERIN K O'SHEA PHD
VP & CHIEF SCI OFF	40.0		$753,361	$0	$45,598	Yes (X)
JOHN PALMISANO
VP FOR INFORMATION TECHNOLOGY effective 11/15	40.0		$31,622	$0	$3,283	Yes (X)
GERALD M RUBIN PHD
VP&EXEC DIR,JANELIA RES CAMPUS	40.0		$744,485	$0	$123,162	Yes (X)
KATHY WYSZYNSKI
VP, HUMAN RESOURCES	40.0		$279,928	$0	$40,532	Yes (X)
RICHARD A PENDER
MAN DIR - US EQUITIES	40.0		$976,092	$0	$53,710		Yes (X)
ROBERT J KOLYER JR
MAN DIR - DIVERSIFIED ASSETS	40.0		$1,459,392	$0	$54,773		Yes (X)
MARK A BARNARD
MAN DIR - PRIVATE EQUITIES	40.0		$1,280,482	$0	$58,403		Yes (X)
STEPHEN M KITSOULIS
MAN DIR - FIXED INCOME	40.0		$903,019	$0	$47,198		Yes (X)
GREGORY DENINNO
MAN DIR - PRIVATE EQUITIES	40.0		$587,265	$0	$56,996		Yes (X)
ANIL MADHOK
MAN DIR - INVESTMENTS & COO	40.0		$1,118,843	$0	$41,031			Yes (X)
DONALD KOCH
MAN DIR - PORTFOLIO STRATEGY	40.0		$978,620	$0	$58,524			Yes (X)
THOMAS R CECH PHD
INVESTIGATOR	40.0		$629,730	$0	$52,258			Yes (X)
RYAN L MATNEY
DIRECTOR-DIVERSIFIED ASSETS	40.0		$603,568	$0	$56,286			Yes (X)
ERIC R KANDEL MD
SENIOR INVESTIGATOR	40.0		$596,905	$0	$58,434			Yes (X)
MOHAMOUD JIBRELL
VP FOR INFORMATION TECHNOLOGY	40.0		$320,220	$0	$158,629				Yes (X)

Field	Value	IRS element (for citing)
Total Reportable Comp From Org	$20,066,117	TotalReportableCompFromOrgAmt
Tot Reportable Comp Rltd Org	$0	TotReportableCompRltdOrgAmt
Total Other Compensation	$1,400,772	TotalOtherCompensationAmt
Indiv Rcvd Greater Than100 K	722	IndivRcvdGreaterThan100KCnt
Former Ofcr Employees Listed	Yes (true)	FormerOfcrEmployeesListedInd
Total Comp Greater Than150 K	Yes (true)	TotalCompGreaterThan150KInd
Compensation From Other Srcs	Yes (true)	CompensationFromOtherSrcsInd

Contractor Compensation ContractorCompensationGrp (5 entries)

Address Line1ContractorAddress/USAddress/AddressLine1Txt	CityContractorAddress/USAddress/CityNm	State AbbreviationContractorAddress/USAddress/StateAbbreviationCd	ZIPContractorAddress/USAddress/ZIPCd	ServicesServicesDesc	CompensationCompensationAmt	Address Line2ContractorAddress/USAddress/AddressLine2Txt
TOURMALET ADVISORS
2150 POST ROAD	FAIRFIELD	CT	06824	INVESTMENT MGT	$8,603,889
ECHO STREET CAPITAL MGR LLC (VIA HHMI II LLC)
850 THIRD AVENUE	NEW YORK	NY	10022	INVESTMENT MGT	$4,641,671
ARAMARK HARRISON LODGING
1101 MARKET ST	PHILADELPHIA	PA	19107	CONFERENCE CTR MGT	$4,161,191
WORKDAY INC
6230 STONERIDGE MALL ROAD	PLEASANTON	CA	94588	IT SOFTWARE CONSULTING	$3,163,837
THE NORTH HIGHLAND COMPANY
550 PHARR	ATLANTA	GA	30305	CONSULTANT	$2,963,032	SUITE 850

Field	Value	IRS element (for citing)
Cntrct Rcvd Greater Than100 K	158	CntrctRcvdGreaterThan100KCnt
Info In Schedule O Part VIII	Yes (X)	InfoInScheduleOPartVIIIInd
All Other Contributions	$19,321,241	AllOtherContributionsAmt
Total Contributions	$19,321,241	TotalContributionsAmt

Program Service Revenue ProgramServiceRevenueGrp (2 entries)

DescDesc	BusinessBusinessCd	Total Revenue ColumnTotalRevenueColumnAmt	Related Or Exempt Func IncomeRelatedOrExemptFuncIncomeAmt
RENTAL INCOME	900099	$2,169,244	$2,169,244
TV & Film Royalties	900099	$53,918	$53,918

Total Oth Program Service Rev TotalOthProgramServiceRevGrp

Field	Value	IRS element (for citing)
Total Revenue Column	$0	TotalRevenueColumnAmt
Related Or Exempt Func Income	$0	RelatedOrExemptFuncIncomeAmt
Unrelated Business Revenue	$0	UnrelatedBusinessRevenueAmt
Exclusion	$0	ExclusionAmt

Field	Value	IRS element (for citing)
Total Program Service Revenue	$2,223,162	TotalProgramServiceRevenueAmt

Investment Income InvestmentIncomeGrp

Field	Value	IRS element (for citing)
Total Revenue Column	$204,038,300	TotalRevenueColumnAmt
Unrelated Business Revenue	-$12,629,452	UnrelatedBusinessRevenueAmt
Exclusion	$216,667,752	ExclusionAmt

Royalties Revenue RoyaltiesRevenueGrp

Field	Value	IRS element (for citing)
Total Revenue Column	$256,701,667	TotalRevenueColumnAmt
Exclusion	$256,701,667	ExclusionAmt

Gross Rents GrossRentsGrp

Field	Value	IRS element (for citing)
Real	$767,720	RealAmt

Less Rental Expenses LessRentalExpensesGrp

Field	Value	IRS element (for citing)
Real	$1,424,636	RealAmt

Rental Income Or Loss RentalIncomeOrLossGrp

Field	Value	IRS element (for citing)
Real	-$656,916	RealAmt
Personal	$0	PersonalAmt

Net Rental Income Or Loss NetRentalIncomeOrLossGrp

Field	Value	IRS element (for citing)
Total Revenue Column	-$656,916	TotalRevenueColumnAmt
Unrelated Business Revenue	-$636,333	UnrelatedBusinessRevenueAmt
Exclusion	-$20,583	ExclusionAmt

Gross Amount Sales Assets GrossAmountSalesAssetsGrp

Field	Value	IRS element (for citing)
Securities	$60,406,321,892	SecuritiesAmt
Other	$11,432,728	OtherAmt

Less Cost Oth Basis Sales Expnss LessCostOthBasisSalesExpnssGrp

Field	Value	IRS element (for citing)
Securities	$59,700,068,593	SecuritiesAmt

Gain Or Loss GainOrLossGrp

Field	Value	IRS element (for citing)
Securities	$706,253,299	SecuritiesAmt
Other	$11,432,728	OtherAmt

Net Gain Or Loss Investments NetGainOrLossInvestmentsGrp

Field	Value	IRS element (for citing)
Total Revenue Column	$717,686,027	TotalRevenueColumnAmt
Unrelated Business Revenue	$11,432,728	UnrelatedBusinessRevenueAmt
Exclusion	$706,253,299	ExclusionAmt

Other Revenue Misc OtherRevenueMiscGrp (3 entries)

DescDesc	BusinessBusinessCd	Total Revenue ColumnTotalRevenueColumnAmt	ExclusionExclusionAmt
CAFETERIA INCOME	900099	$271,442	$271,442
INVESTMENT EXPENSE REBATE	900099	$172,767	$172,767
CASH DISCOUNTS	900099	$132,378	$132,378

Miscellaneous Revenue MiscellaneousRevenueGrp

Field	Value	IRS element (for citing)
Total Revenue Column	$430,805	TotalRevenueColumnAmt
Related Or Exempt Func Income	$0	RelatedOrExemptFuncIncomeAmt
Unrelated Business Revenue	$0	UnrelatedBusinessRevenueAmt
Exclusion	$430,805	ExclusionAmt

Field	Value	IRS element (for citing)
Other Revenue Total	$1,007,392	OtherRevenueTotalAmt

Total Revenue TotalRevenueGrp

Field	Value	IRS element (for citing)
Total Revenue Column	$1,200,320,873	TotalRevenueColumnAmt
Related Or Exempt Func Income	$2,223,162	RelatedOrExemptFuncIncomeAmt
Unrelated Business Revenue	-$1,833,057	UnrelatedBusinessRevenueAmt
Exclusion	$1,180,609,527	ExclusionAmt

Grants To Domestic Orgs GrantsToDomesticOrgsGrp

Field	Value	IRS element (for citing)
Total	$31,593,272	TotalAmt
Program Services	$31,593,272	ProgramServicesAmt

Grants To Domestic Individuals GrantsToDomesticIndividualsGrp

Field	Value	IRS element (for citing)
Total	$86,398,776	TotalAmt
Program Services	$86,398,776	ProgramServicesAmt

Foreign Grants ForeignGrantsGrp

Field	Value	IRS element (for citing)
Total	$20,801,000	TotalAmt
Program Services	$20,801,000	ProgramServicesAmt

Comp Current Ofcr Directors CompCurrentOfcrDirectorsGrp

Field	Value	IRS element (for citing)
Total	$15,274,181	TotalAmt
Program Services	$2,453,676	ProgramServicesAmt
Management And General	$12,820,505	ManagementAndGeneralAmt

Comp Disqual Persons CompDisqualPersonsGrp

Field	Value	IRS element (for citing)
Total	$220,039	TotalAmt
Management And General	$220,039	ManagementAndGeneralAmt

Other Salaries And Wages OtherSalariesAndWagesGrp

Field	Value	IRS element (for citing)
Total	$266,923,649	TotalAmt
Program Services	$235,196,437	ProgramServicesAmt
Management And General	$31,727,212	ManagementAndGeneralAmt

Pension Plan Contributions PensionPlanContributionsGrp

Field	Value	IRS element (for citing)
Total	$22,662,921	TotalAmt
Program Services	$19,940,803	ProgramServicesAmt
Management And General	$2,722,118	ManagementAndGeneralAmt

Other Employee Benefits OtherEmployeeBenefitsGrp

Field	Value	IRS element (for citing)
Total	$115,950,973	TotalAmt
Program Services	$99,333,829	ProgramServicesAmt
Management And General	$16,617,144	ManagementAndGeneralAmt

Payroll Taxes PayrollTaxesGrp

Field	Value	IRS element (for citing)
Total	$17,522,408	TotalAmt
Program Services	$15,181,179	ProgramServicesAmt
Management And General	$2,341,229	ManagementAndGeneralAmt

Fees For Services Legal FeesForServicesLegalGrp

Field	Value	IRS element (for citing)
Total	$3,710,170	TotalAmt
Program Services	$2,083,137	ProgramServicesAmt
Management And General	$1,627,033	ManagementAndGeneralAmt

Fees For Services Accounting FeesForServicesAccountingGrp

Field	Value	IRS element (for citing)
Total	$971,762	TotalAmt
Program Services	$12,212	ProgramServicesAmt
Management And General	$959,550	ManagementAndGeneralAmt

Fees For Srvc Invst Mgmnt Fees FeesForSrvcInvstMgmntFeesGrp

Field	Value	IRS element (for citing)
Total	$67,458,786	TotalAmt
Management And General	$67,458,786	ManagementAndGeneralAmt

Fees For Services Other FeesForServicesOtherGrp

Field	Value	IRS element (for citing)
Total	$40,629,075	TotalAmt
Program Services	$26,043,956	ProgramServicesAmt
Management And General	$14,585,119	ManagementAndGeneralAmt
Fundraising	$0	FundraisingAmt

Office Expenses OfficeExpensesGrp

Field	Value	IRS element (for citing)
Total	$4,826,570	TotalAmt
Program Services	$3,550,890	ProgramServicesAmt
Management And General	$1,275,680	ManagementAndGeneralAmt

Information Technology InformationTechnologyGrp

Field	Value	IRS element (for citing)
Total	$9,401,261	TotalAmt
Program Services	$659,392	ProgramServicesAmt
Management And General	$8,741,869	ManagementAndGeneralAmt

Royalties RoyaltiesGrp

Field	Value	IRS element (for citing)
Total	$23,132	TotalAmt
Program Services	$6,760	ProgramServicesAmt
Management And General	$16,372	ManagementAndGeneralAmt

Occupancy OccupancyGrp

Field	Value	IRS element (for citing)
Total	$78,412,496	TotalAmt
Program Services	$78,779,948	ProgramServicesAmt
Management And General	-$367,452	ManagementAndGeneralAmt

Travel TravelGrp

Field	Value	IRS element (for citing)
Total	$8,136,399	TotalAmt
Program Services	$6,732,161	ProgramServicesAmt
Management And General	$1,404,238	ManagementAndGeneralAmt

Conferences Meetings ConferencesMeetingsGrp

Field	Value	IRS element (for citing)
Total	$4,072,244	TotalAmt
Program Services	$2,713,796	ProgramServicesAmt
Management And General	$1,358,448	ManagementAndGeneralAmt

Interest InterestGrp

Field	Value	IRS element (for citing)
Total	$76,286,215	TotalAmt
Program Services	$308,533	ProgramServicesAmt
Management And General	$75,977,682	ManagementAndGeneralAmt

Depreciation Depletion DepreciationDepletionGrp

Field	Value	IRS element (for citing)
Total	$84,426,346	TotalAmt
Program Services	$75,119,977	ProgramServicesAmt
Management And General	$9,306,369	ManagementAndGeneralAmt

Insurance InsuranceGrp

Field	Value	IRS element (for citing)
Total	$486,689	TotalAmt
Program Services	$164,385	ProgramServicesAmt
Management And General	$322,304	ManagementAndGeneralAmt

Other Expenses OtherExpensesGrp (4 entries)

DescDesc	TotalTotalAmt	Program ServicesProgramServicesAmt	Management And GeneralManagementAndGeneralAmt
LAB & OTHER SCIENTIFIC SUPPLIES	$125,680,795	$124,497,069	$1,183,726
MINOR EQUIPMENT & RENOVATIONS	$24,377,408	$23,268,389	$1,109,019
EQUIPMENT MAINTENANCE	$16,250,139	$14,809,624	$1,440,515
Income Tax	$236,624		$236,624

All Other Expenses AllOtherExpensesGrp

Field	Value	IRS element (for citing)
Total	$10,743,858	TotalAmt
Program Services	$10,250,495	ProgramServicesAmt
Management And General	$493,363	ManagementAndGeneralAmt
Fundraising	$0	FundraisingAmt

Total Functional Expenses TotalFunctionalExpensesGrp

Field	Value	IRS element (for citing)
Total	$1,133,477,188	TotalAmt
Program Services	$879,899,696	ProgramServicesAmt
Management And General	$253,577,492	ManagementAndGeneralAmt
Fundraising	$0	FundraisingAmt

Savings And Temp Cash Invst SavingsAndTempCashInvstGrp

Field	Value	IRS element (for citing)
BOY	$261,159,459	BOYAmt
EOY	$331,496,720	EOYAmt

Receivables From Officers Etc ReceivablesFromOfficersEtcGrp

Field	Value	IRS element (for citing)
EOY	$0	EOYAmt

Rcvbl From Disqualified Prsn RcvblFromDisqualifiedPrsnGrp

Field	Value	IRS element (for citing)
EOY	$0	EOYAmt

Prepaid Expenses Defrd Charges PrepaidExpensesDefrdChargesGrp

Field	Value	IRS element (for citing)
BOY	$12,181,144	BOYAmt
EOY	$10,034,921	EOYAmt

Field	Value	IRS element (for citing)
Land Bldg Equip Cost Or Other Bss	$1,787,340,604	LandBldgEquipCostOrOtherBssAmt
Land Bldg Equip Accum Deprec	$1,048,522,494	LandBldgEquipAccumDeprecAmt

Land Bldg Equip Basis Net LandBldgEquipBasisNetGrp

Field	Value	IRS element (for citing)
BOY	$761,222,925	BOYAmt
EOY	$738,818,110	EOYAmt

Investments Pub Traded Sec InvestmentsPubTradedSecGrp

Field	Value	IRS element (for citing)
BOY	$7,011,005,370	BOYAmt
EOY	$6,611,550,109	EOYAmt

Investments Other Securities InvestmentsOtherSecuritiesGrp

Field	Value	IRS element (for citing)
BOY	$13,361,529,118	BOYAmt
EOY	$13,078,172,731	EOYAmt

Investments Program Related InvestmentsProgramRelatedGrp

Field	Value	IRS element (for citing)
BOY	$0	BOYAmt

Other Assets Total OtherAssetsTotalGrp

Field	Value	IRS element (for citing)
BOY	$286,638,422	BOYAmt
EOY	$312,429,699	EOYAmt

Total Assets TotalAssetsGrp

Field	Value	IRS element (for citing)
BOY	$21,693,736,438	BOYAmt
EOY	$21,082,502,290	EOYAmt

Accounts Payable Accr Expnss AccountsPayableAccrExpnssGrp

Field	Value	IRS element (for citing)
BOY	$493,609,336	BOYAmt
EOY	$555,985,053	EOYAmt

Grants Payable GrantsPayableGrp

Field	Value	IRS element (for citing)
BOY	$118,378,619	BOYAmt
EOY	$161,167,676	EOYAmt

Tax Exempt Bond Liabilities TaxExemptBondLiabilitiesGrp

Field	Value	IRS element (for citing)
BOY	$716,130,000	BOYAmt
EOY	$716,130,000	EOYAmt

Unsecured Notes Loans Payable UnsecuredNotesLoansPayableGrp

Field	Value	IRS element (for citing)
BOY	$1,238,405,223	BOYAmt
EOY	$1,234,673,954	EOYAmt

Other Liabilities OtherLiabilitiesGrp

Field	Value	IRS element (for citing)
BOY	$955,978,144	BOYAmt
EOY	$638,986,054	EOYAmt

Total Liabilities TotalLiabilitiesGrp

Field	Value	IRS element (for citing)
BOY	$3,522,501,322	BOYAmt
EOY	$3,306,942,737	EOYAmt

Field	Value	IRS element (for citing)
Organization Follows SFAS117	Yes (X)	OrganizationFollowsSFAS117Ind

Unrestricted Net Assets UnrestrictedNetAssetsGrp

Field	Value	IRS element (for citing)
BOY	$18,171,235,116	BOYAmt
EOY	$17,775,559,553	EOYAmt

Total Net Assets Fund Balance TotalNetAssetsFundBalanceGrp

Field	Value	IRS element (for citing)
BOY	$18,171,235,116	BOYAmt
EOY	$17,775,559,553	EOYAmt

Tot Liab Net Assets Fund Balance TotLiabNetAssetsFundBalanceGrp

Field	Value	IRS element (for citing)
BOY	$21,693,736,438	BOYAmt
EOY	$21,082,502,290	EOYAmt

Field	Value	IRS element (for citing)
Reconcilation Revenue Expnss	$66,843,685	ReconcilationRevenueExpnssAmt
Net Unrlzd Gains Losses Invst	-$462,519,248	NetUnrlzdGainsLossesInvstAmt
Other Changes In Net Assets	$0	OtherChangesInNetAssetsAmt
Method Of Accounting Accrual	Yes (X)	MethodOfAccountingAccrualInd
Accountant Compile Or Review	false	AccountantCompileOrReviewInd
FS Audited	Yes (true)	FSAuditedInd

FS Audited Basis FSAuditedBasisGrp

Field	Value	IRS element (for citing)
Consolidated Basis Fincl Stmt	Yes (X)	ConsolidatedBasisFinclStmtInd

Field	Value	IRS element (for citing)
Audit Committee	Yes (true)	AuditCommitteeInd
Federal Grant Audit Required	false	FederalGrantAuditRequiredInd

Schedule A IRS990ScheduleA

Field	Value	IRS element (for citing)
Medical Research Organization	Yes (X)	MedicalResearchOrganizationInd

Hospital Name And Address HospitalNameAndAddressGrp

Supported Organization Name SupportedOrganizationName

Field	Value	IRS element (for citing)
Business Name Line1	Brigham Womens Hospital	BusinessNameLine1Txt

Field	Value	IRS element (for citing)
City	Boston	CityNm
State Abbreviation	MA	StateAbbreviationCd

Schedule B IRS990ScheduleB

Contributor Information ContributorInformationGrp

Field	Value	IRS element (for citing)
Contributor	RESTRICTED	ContributorNum

Contributor Business Name ContributorBusinessName

Field	Value	IRS element (for citing)
Business Name Line1	RESTRICTED	BusinessNameLine1

Contributor US Address ContributorUSAddress

Field	Value	IRS element (for citing)
Address Line1	RESTRICTED	AddressLine1
Address Line2	RESTRICTED	AddressLine2
City	RESTRICTED	City
State	RESTRICTED	State
ZIP Code	RESTRICTED	ZIPCode

Field	Value	IRS element (for citing)
Total Contributions	RESTRICTED	TotalContributionsAmt

Schedule C IRS990ScheduleC

Field	Value	IRS element (for citing)
Volunteers	false	VolunteersInd
Paid Staff Or Management	false	PaidStaffOrManagementInd
Media Advertisements	false	MediaAdvertisementsInd
Mailings Members	false	MailingsMembersInd
Publications Or Broadcast	false	PublicationsOrBroadcastInd
Grants Other Organizations	false	GrantsOtherOrganizationsInd
Direct Contact Legislators	false	DirectContactLegislatorsInd
Rallies Demonstrations	false	RalliesDemonstrationsInd
Other Activities	Yes (true)	OtherActivitiesInd
Other Activities	$2,267	OtherActivitiesAmt
Total Lobbying Expenditures	$2,267	TotalLobbyingExpendituresAmt
Not Described Section501c3	false	NotDescribedSection501c3Ind

Supplemental Information Detail SupplementalInformationDetail (2 entries)

Form And Line ReferenceFormAndLineReferenceDesc	ExplanationExplanationTxt
Schedule C, Part II-B, Line 1 DETAILED DESCRIPTION OF THE LOBBYING ACTIVITY	OTHER ACTIVITIES, SCHEDULE C, PART II-B, LINE 1I (OTHER ACTIVITIES) DURING THE FISCAL YEAR, HHMI WAS A MEMBER OF A NUMBER OF NON-PROFIT ORGANIZATIONS THAT ENGAGED IN LOBBYING ACTIVITIES ON BEHALF OF THEIR MEMBERSHIPS. HHMI IS REPORTING AS LOBBYING EXPENDITURES A PORTION OF THE MEMBERSHIP DUES THAT HHMI PAID TO THESE ORGANIZATIONS.
Schedule C, Part II-B, Line 1 DETAILED DESCRIPTION OF THE LOBBYING ACTIVITY	OTHER ACTIVITIES, SCHEDULE C, PART II-B, LINE 1I (OTHER ACTIVITIES) DURING THE FISCAL YEAR, HHMI WAS A MEMBER OF A NUMBER OF NON-PROFIT ORGANIZATIONS THAT ENGAGED IN LOBBYING ACTIVITIES ON BEHALF OF THEIR MEMBERSHIPS. HHMI IS REPORTING AS LOBBYING EXPENDITURES A PORTION OF THE MEMBERSHIP DUES THAT HHMI PAID TO THESE ORGANIZATIONS.

Schedule D IRS990ScheduleD

Land LandGrp

Field	Value	IRS element (for citing)
Investment Cost Or Other Basis	$807,737	InvestmentCostOrOtherBasisAmt
Other Cost Or Other Basis	$35,488,028	OtherCostOrOtherBasisAmt
Book Value	$36,295,765	BookValueAmt

Buildings BuildingsGrp

Field	Value	IRS element (for citing)
Investment Cost Or Other Basis	$10,248,413	InvestmentCostOrOtherBasisAmt
Other Cost Or Other Basis	$751,765,532	OtherCostOrOtherBasisAmt
Depreciation	$267,784,380	DepreciationAmt
Book Value	$494,229,565	BookValueAmt

Leasehold Improvements LeaseholdImprovementsGrp

Field	Value	IRS element (for citing)
Other Cost Or Other Basis	$383,497,469	OtherCostOrOtherBasisAmt
Depreciation	$346,414,306	DepreciationAmt
Book Value	$37,083,163	BookValueAmt

Equipment EquipmentGrp

Field	Value	IRS element (for citing)
Other Cost Or Other Basis	$536,521,827	OtherCostOrOtherBasisAmt
Depreciation	$434,323,808	DepreciationAmt
Book Value	$102,198,019	BookValueAmt

Other Land Buildings OtherLandBuildingsGrp

Field	Value	IRS element (for citing)
Investment Cost Or Other Basis	$921,448	InvestmentCostOrOtherBasisAmt
Other Cost Or Other Basis	$68,090,150	OtherCostOrOtherBasisAmt
Book Value	$69,011,598	BookValueAmt

Field	Value	IRS element (for citing)
Total Book Value Land Buildings	$738,818,110	TotalBookValueLandBuildingsAmt

Other Securities OtherSecuritiesGrp (5 entries)

DescDesc	Book ValueBookValueAmt	Method ValuationMethodValuationCd
PRIVATE EQUITY & REAL ESTATE	$5,001,889,119	F
DISTRESSED & CREDIT SENSITIVE	$2,259,037,867	F
HEDGED EQUITY	$2,317,213,493	F
MARKET NEUTRAL	$1,283,983,391	F
EQUITY COMMINGLED	$2,216,048,861	F

Field	Value	IRS element (for citing)
Total Book Value Securities	$13,078,172,731	TotalBookValueSecuritiesAmt

Other Liabilities Org OtherLiabilitiesOrgGrp (14 entries)

DescDesc	AmtAmt
DERIVATIVE LIABILITIES	$1,803,600
SHORT POSITIONS	$327,937,043
INVESTMENT PURCH PENDING SALES	$39,830,354
CURRENCY EXCH CONTRACTS PAY	$3,755,043
CREDIT DEFAULT SWAP
PAY REALIZED GAINS ON FUTURES	$113,838
DEFERRED COMPENSATION LIAB	$39,001,217
SWAP UNREALIZED LOSS	$219,572,748
INVESTMENT MANAGEMENT FEES PAYABLE	$4,424,900
EQUITY SWAP
DEFERRED INCOME	$740,712
INTEREST ON REPURCHASE OBLIGATIONS
REPURCHASE OBLIGATIONS
CONTRACT FOR DIFFERENCES LIABILITY	$1,806,599

Field	Value	IRS element (for citing)
Total Liability	$638,986,054	TotalLiabilityAmt
Total Rev Etc Audited Fincl Stmt	$632,634,951	TotalRevEtcAuditedFinclStmtAmt
Net Unrealized Gains Invst	-$462,519,248	NetUnrealizedGainsInvstAmt
Other Revenue	$0	OtherRevenueAmt
Revenue Not Reported	-$462,519,248	RevenueNotReportedAmt
Revenue Subtotal	$1,095,154,199	RevenueSubtotalAmt
Investment Expenses Not Incld	$106,591,310	InvestmentExpensesNotIncldAmt
Other Revenues Not Included	-$1,424,636	OtherRevenuesNotIncludedAmt
Revenue Not Reported Fincl Stmt	$105,166,674	RevenueNotReportedFinclStmtAmt
Total Revenue Per Form990	$1,200,320,873	TotalRevenuePerForm990Amt
Tot Expns Etc Audited Fincl Stmt	$1,028,310,514	TotExpnsEtcAuditedFinclStmtAmt
Other Expenses Included	$0	OtherExpensesIncludedAmt
Expenses Not Reported	$0	ExpensesNotReportedAmt
Expenses Subtotal	$1,028,310,514	ExpensesSubtotalAmt
Investment Expenses Not Incld2	$106,591,310	InvestmentExpensesNotIncld2Amt
Other Expenses Not Included	-$1,424,636	OtherExpensesNotIncludedAmt
Expenses Not Rpt Fincl Stmt	$105,166,674	ExpensesNotRptFinclStmtAmt
Total Expenses Per Form990	$1,133,477,188	TotalExpensesPerForm990Amt

Supplemental Information Detail SupplementalInformationDetail (2 entries)

Form And Line ReferenceFormAndLineReferenceDesc	ExplanationExplanationTxt
Schedule D, Part XI, Line 4(b) Other revenues in form 990 not in audited financial statements	Rental Expenses - -1424636
Schedule D, Part XII, Line 4(b) Other expenses in form 990 not in audited financial statements	Rental Expenses - -1424636

Schedule F IRS990ScheduleF

Field	Value	IRS element (for citing)
Grant Records Maintained	Yes (true)	GrantRecordsMaintainedInd

Account Activities Outside US AccountActivitiesOutsideUSGrp (13 entries)

RegionRegionTxt	EmployeeEmployeeCnt	Type Of Activities ConductedTypeOfActivitiesConductedTxt	Specific Services ProvidedSpecificServicesProvidedTxt	Region Total ExpendituresRegionTotalExpendituresAmt
Sub-Saharan Africa	1	Grantmaking	MEDICAL RESEARCH	$21,000,000
Sub-Saharan Africa	0	Program Services	Medical Research	$113,932
Europe (Including Iceland and Greenland)	0	Grantmaking	Investigator Education	$21,000
Sub-Saharan Africa	0	Investments		$41,296,611
North America (Canada & Mexico only)	0	Investments		$214,473,645
Europe (Including Iceland and Greenland)	0	Investments		$1,267,663,712
East Asia and the Pacific	0	Investments		$568,220,903
Central America and the Caribbean	0	Investments		$6,073,683,993
South America	0	Investments		$48,225,203
South Asia	0	Investments		$51,112,999
Middle East and North Africa	0	Investments		$6,553,062
Russia and Neighboring States	0	Investments		$4,192,930
Europe (Including Iceland and Greenland)	0	Program Services	Open Access	$3,113,379

Field	Value	IRS element (for citing)
Subtotal Offices	0	SubtotalOfficesCnt
Subtotal Employees	1	SubtotalEmployeesCnt
Continutation Total Office	0	ContinutationTotalOfficeCnt
Continutation Total Employee	0	ContinutationTotalEmployeeCnt
Total Office	0	TotalOfficeCnt
Total Employee	1	TotalEmployeeCnt
Subtotal Spent	$8,299,671,369	SubtotalSpentAmt
Continuation Spent	$0	ContinuationSpentAmt
Total Spent	$8,299,671,369	TotalSpentAmt

Grants To Org Outside US GrantsToOrgOutsideUSGrp (2 entries)

RegionRegionTxt	Purpose Of GrantPurposeOfGrantTxt	Cash GrantCashGrantAmt	Manner Of Cash DisbursementMannerOfCashDisbursementTxt
Europe (Including Iceland and Greenland)	EDUCATION IN MEDICAL RESEARCH	$21,000	WT
Sub-Saharan Africa	HIV/TB	$21,000,000	WT

Field	Value	IRS element (for citing)
Total501c3 Org	2	Total501c3OrgCnt
Total Other Org	0	TotalOtherOrgCnt
Transfer To Foreign Corp	Yes (true)	TransferToForeignCorpInd
Interest In Foreign Trust	Yes (true)	InterestInForeignTrustInd
Foreign Corp Ownership	Yes (true)	ForeignCorpOwnershipInd
Passive Foreign Investmest Co	Yes (true)	PassiveForeignInvestmestCoInd
Foreign Partnership	Yes (true)	ForeignPartnershipInd
Boycott Countries	false	BoycottCountriesInd

Supplemental Information Detail SupplementalInformationDetail (2 entries)

Form And Line ReferenceFormAndLineReferenceDesc

ExplanationExplanationTxt

Schedule F, Part I, Line 2 Procedures for monitoring use of grant funds

During its 2016 fiscal year, HHMI continued to support International Research Scholars selected through one or more competitions open to all eligible applicants. Eligibility requirements included, but were not limited to, a full-time appointment at a nonprofit scientific research organization in a country other than the United States, and a research focus on basic biological processes or disease mechanisms. Qualified applicants were evaluated by a panel of scientific experts with final selections made by HHMI leadership. The disbursement of grant funds to support the work of International Early Career Scientists and Senior International Research Scholars is made in accordance with all applicable U.S. laws. Funds are paid to an institutional account. In order to monitor the activities and productivity of the grants, each scientist is required to submit an annual progress report concerning his or her research and each grantee institution is required to submit annual financial reports. These reports are reviewed by HHMI staff site visits and audits are conducted if warranted and grantees attend scientific meetings of HHMI US-based scientists. In 2009, HHMI helped launch the KwaZulu-Natal Research Institute for TB-HIV (K-RITH) in collaboration with the University of KwaZulu-Natal (UKZN), and has provided significant funding to support its research efforts. As discussed in further detail on Schedule O, in 2016, in a move to improve the health of people locally and globally, K-RITH joined forces with the Africa Centre for Population Health to form a groundbreaking new interdisciplinary institute to fight tuberculosis (TB), HIV and related diseases. The new organization, the Africa Health Research Institute, is located at the heart of South Africa's TB and HIV co-epidemic in KwaZulu-Natal Province. The effort brings together the Africa Centre's detailed population data from over 100,000 participants, with K-RITH's expertise in basic science and its world-class laboratory facilities. The new venture is made possible through grants from HHMI and Wellcome Trust, with the University College London and UKZN as significant academic partners. The Africa Health Research Institute is committed to working towards the elimination of HIV and TB.

Schedule F, Part I, Line 2 PROCEDURES FOR MONITORING USE OF GRANT FUNDS

Schedule I IRS990ScheduleI

Field	Value	IRS element (for citing)
Grant Records Maintained	Yes (true)	GrantRecordsMaintainedInd

Recipient Table RecipientTable (85 entries)

Address Line1USAddress/AddressLine1Txt	CityUSAddress/CityNm	State AbbreviationUSAddress/StateAbbreviationCd	ZIPUSAddress/ZIPCd	Recipient EINRecipientEIN	IRC SectionIRCSectionDesc	Cash GrantCashGrantAmt	Non Cash AssistanceNonCashAssistanceAmt	Purpose Of GrantPurposeOfGrantTxt
Tuskegee University
Tuskegee University	Tuskegee	AL	36088	630288878	501 (c) 3	$250,000	$0	Undergrad Initiatives
Hope College
Hope College	Holland	MI	49423	381381271	501 (c) 3	$39,316	$0	Undergrad Initiatives
Millsap College
Millsap College	Jackson	MS	39210	640303084	501 (c) 3	$41,462	$0	Undergrad Initiatives
Macalester College
Macalester College	St Paul	MN	55105	410693962	501 (c) 3	$50,000	$0	Undergrad Initiatives
Assoc of American Colleges & Univ
1818 R Street NW	Washington	DC	20009	521945674	501 (c) 3	$500,000	$0	Undergrad Initiatives
Yale University
Yale University	New Haven	CT	06520	060646973	501 (c) 3	$600,000	$0	Ugrad Science Ed
UC - Santa Barbara
UC - Santa Barbara	Santa Barbara	CA	93106	956006145	501 (c) 3	$50,000	$0	Ugrad Science Ed
UC- Los Angeles
UC- Los Angeles	Los Angeles	CA	90095	956006143	501 (c) 3	$50,000	$0	Ugrad Science Ed
Duke University
Duke University	Durham	NC	27706	560532129	501 (c) 3	$50,600	$0	Ugrad Science Ed
Florida International Univ
Florida International Univ	Miami	FL	33199	650177616	501 (c) 3	$50,000	$0	Ugrad Science Ed
Indiana Univ of Pennsylvania
Indiana Univ of Pennsylvania	Indiana	PA	15705	251753112	501 (c) 3	$1,860,000	$0	Ugrad Science Ed
UC - San Francisco
UC - San Francisco	San Francisco	CA	94143	946036493	501 (c) 3	$19,422	$0	EXROP Program - Housing
Travel Expense paid on behalf of grantees-Carl Hotel
198 Carl Street	San Francisco	CA	94117	943356764		$6,068	$0	EXROP Program - Travel
Univ of Washington
Univ of Washington	Seattle	WA	98195	916001537	501 (c) 3	$7,594	$0	EXROP Program - Housing
Travel Expense paid on behalf of grantees-United
233 S Wacker Drive	Chicago	IL	60606	742099724		$6,103	$0	EXROP Program - Travel
Stanford Univ
Stanford Univ	Palo Alto	CA	94305	941156365	501 (c) 3	$37,035	$0	EXROP Program - Housing
Univ of Michigan
Univ of Michigan	Ann Arbor	MI	48109	386006309	501 (c) 3	$9,593	$0	EXROP Program - Housing
Univ of Colorado
Univ of Colorado	Boulder	CO	80309	846000555	501 (c) 3	$9,518	$0	EXROP Program - Housing
Travel Expense paid on behalf of grantees-AMR Corp
4333 Amon Carter Blvd	Fort Worth	TX	76155	751825172		$8,549	$0	EXROP Program - Travel
UC - Berkeley
UC - Berkeley	Berkeley	CA	94720	946002123	501 (c) 3	$17,060	$0	EXROP Program - Housing
Travel Expense paid on behalf of grantees-Delta
PO Box 20706	Atlanta	GA	30354	580218548		$6,738	$0	EXROP Program - Travel
Columbia University
Columbia University	New York	NY	10027	135598093	501 (c) 3	$18,100	$0	EXROP Program - Housing
Rockefeller University
Rockefeller University	New York	NY	10065	131624158	501 (c) 3	$5,082	$0	EXROP Program - Housing
Harvard University
Harvard University	Cambridge	MA	02138	042103580	501 (c) 3	$63,503	$0	EXROP Program - Housing
MIT
MIT	Cambridge	MA	02139	042103594	501 (c) 3	$18,926	$0	EXROP Program - Housing
UC- San Diego
UC- San Diego	La Jolla	CA	92093	956006144	501 (c) 3	$6,966	$0	EXROP Program - Housing
Yale University
Yale University	New Haven	CT	06520	060646973	501 (c) 3	$14,634	$0	EXROP Program - Housing
St Jude's Childrens Research Hospital
262 Danny Thomas Place	Memphis	TN	38105	620646012	501 (c) 3	$5,143	$0	EXROP Program - Housing
UC- Los Angeles
UC- Los Angeles	Los Angeles	CA	90095	956006143	501 (c) 3	$7,321	$0	EXROP Program - Housing
Univ of Texas
Univ of Texas	Austin	TX	78712	746000203	501 (c) 3	$5,806	$0	EXROP Program - Housing
UC - Berkeley
UC - Berkeley	Berkeley	CA	94720	946002123	501 (c) 3	$51,500	$0	University (Doctoral)
Univ of Maryland
Univ of Maryland	Baltimore	MD	21201	526002033	501 (c) 3	$10,000	$0	Minority Serving Inst
Audubon Naturalist Soc
8940 Jones Mill Rd	Chevy Chase	MD	20815	530233715	501 (c) 3	$53,750	$0	Local Inititative
Chesapeake Bay Foundation
162 Prince George St	Annapolis	MD	21401	526065757	501 (c) 3	$162,500	$0	Local Inititative
PG County Public Schools
14201 School Lane	Upper Marlboro	MD	20772	526000992	501 (c) 3	$41,875	$0	Local Inititative
Montgomery Cty PS Educ Found
850 Hungerford Dr	Rockville	MD	20850	521804509	501 (c) 3	$545,000	$0	Local Inititative
Loudoun Cty Public Schools
21000 Education Court	Leesburg	VA	20176	546001395	501 (c) 3	$1,000,000	$0	PreCollege Science - Other
Yale University
Yale University	New Haven	CT	06520	060646973	501 (c) 3	$30,000	$0	Science Education Alliance
Biological Sciences Curriculum Study
CO State Univ	Colorado Springs	CO	80918	840622557	501 (c) 3	$249,948	$0	BSCS NOVA
National Academy of Sciences
2101 Constitution Avenue NW	Washington	DC	20001	530196932	501 (c) 3	$240,000	$0	Science Education
ResearchAmerica
1101 King St Suite 250	Chantilly	VA	20153	521609875	501 (c) 3	$60,000	$0	Program Assessment
Grinnell College
Grinnell College	Grinnell	IA	50112	430680387	501 (c) 3	$100,000	$0	Science Education
UC- Los Angeles
UC- Los Angeles	Los Angeles	CA	90095	956006143	501 (c) 3	$31,950	$0	Science Education
The Conversation US Inc
28 Fairfax St	West Newton	MA	02465	460906774	501 (c) 3	$500,000	$0	Science Journalism
UC - San Diego
UC - San Diego	La Jolla	CA	92093	956006144	501 (c) 3	$400,000	$0	Medical Research
UC - San Francisco
UC - San Francisco	San Francisco	CA	94143	946036493	501 (c) 3	$124,781	$0	Medical Research
CA Inst of Technology
CA Inst of Technology	Pasadena	CA	91125	951643307	501 (c) 3	$2,061,182	$0	Medical Research
NYU
NYU	New York	NY	10003	135562308	501 (c) 3	$390,970	$0	Medical Research
Eastern Mennonite Univ
Eastern Mennonite Univ	Harrisonburg	VA	22802	540575812	501 (c) 3	$130,000	$0	Medical Research
Allen Institute for Brain Science
Allen Institute for Brain Science	Seattle	WA	98103	912155317	501 (c) 3	$42,847	$0	Medical Research
Beth Israel Deaconess Medical Ctr
Beth Israel Deaconess Medical Ctr	Boston	MA	02215	042103881	501 (c) 3	$400,392	$0	Medical Research
Columbia University
Columbia University	New York	NY	10027	135598093	501 (c) 3	$483,224	$0	Medical Research
Duke University
Duke University	Durham	NC	27706	560532129	501 (c) 3	$1,546,139	$0	Medical Research
Fred Hutchinson Cancer Research Ctr
Fred Hutchinson Cancer Research Ctr	Seattle	WA	98109	237156071	501 (c) 3	$367,652	$0	Medical Research
Harvard University
Harvard University	Cambridge	MA	02138	042103580	501 (c) 3	$250,057	$0	Medical Research
Johns Hopkins Univ
Johns Hopkins Univ	Baltimore	MD	21218	520595110	501 (c) 3	$199,580	$0	Medical Research
Massachusetts General Hosp
Massachusetts General Hosp	Boston	MA	02129	042697983	501 (c) 3	$178,746	$0	Medical Research
MIT
MIT	Cambridge	MA	02139	042103594	501 (c) 3	$987,288	$0	Medical Research
Northwestern Univ
Northwestern Univ	Evanston	IL	60208	362167817	501 (c) 3	$145,608	$0	Medical Research
Oregon Health Science Univ
Oregon Health Science Univ	Portland	OR	97239	931176109	501 (c) 3	$1,708,675	$0	Medical Research
Rockefeller University
Rockefeller University	New York	NY	10065	131624158	501 (c) 3	$263,084	$0	Medical Research
Salk Institute
Salk Institute	La Jolla	CA	92037	952160097	501 (c) 3	$285,996	$0	Medical Research
Stanford Univ
Stanford Univ	Palo Alto	CA	94305	941156365	501 (c) 3	$569,456	$0	Medical Research
Univ of Texas
Univ of Texas	Austin	TX	78712	746000203	501 (c) 3	$455,760	$0	Medical Research
UC - Berkeley
UC - Berkeley	Berkeley	CA	94720	946002123	501 (c) 3	$497,652	$0	Medical Research
UC - San Diego
UC - San Diego	La Jolla	CA	92093	956006144	501 (c) 3	$461,910	$0	Medical Research
Univ of Chicago
Univ of Chicago	Chicago	IL	60637	362177139	501 (c) 3	$368,584	$0	Medical Research
Univ of Colorado
Univ of Colorado	Boulder	CO	80309	846000555	501 (c) 3	$470,191	$0	Medical Research
Univ of Florida
Univ of Florida	Gainesville	FL	32611	596002052	501 (c) 3	$324,262	$0	Medical Research
Univ of Massachusetts
Univ of Massachusetts	Worchester	MA	01605	043167352	501 (c) 3	$249,438	$0	Medical Research
Univ of Maryland
Univ of Maryland	Baltimore	MD	21201	526002033	501 (c) 3	$457,440	$0	Medical Research
Univ of Michigan
Univ of Michigan	Ann Arbor	MI	48109	386006309	501 (c) 3	$458,607	$0	Medical Research
Univ of North Carolina
Univ of North Carolina	Chapel Hill	NC	27599	566001393	501 (c) 3	$216,914	$0	Medical Research
Univ of Pennsylvania
Univ of Pennsylvania	Philadelphia	PA	19104	231352685	501 (c) 3	$1,380,218	$0	Medical Research
Univ of Utah
Univ of Utah	Salt Lake City	UT	84112	876000525	501 (c) 3	$4,302,416	$0	Medical Research
Univ of Washington
Univ of Washington	Seattle	WA	98195	916001537	501 (c) 3	$1,193,516	$0	Medical Research
Yale University
Yale University	New Haven	CT	06520	060646973	501 (c) 3	$276,476	$0	Medical Research
Damon Runyon Cancer Research Foundation
Damon Runyon Cancer Res	New York	NY	10006	131933825	501 (c) 3	$1,412,000	$0	Postdoctoral Fellowships
Jane Coffin Childs Memorial Fund for Medical Res
Jane Coffin Childs Mem Fund Med Res	New Haven	CT	06510	066034840	501 (c) 3	$1,259,922	$0	Postdoctoral Fellowships
The Helen Hay Whitney Foundation
The Helen Hay Whitney Foundation	New York	NY	10956	131677403	501 (c) 3	$1,326,000	$0	Postdoctoral Fellowships
Life Sciences Research Foundation
Life Sciences Research Foundation	Baltimore	MD	21218	521231801	501 (c) 3	$1,472,000	$0	Postdoctoral Fellowships
FIU Foundation Inc
11200 SW 8TH ST	Miami	FL	33199	650177616	501 (c) 3	$10,000	$0	UTeach
University of North Texas
1155 UNION CIRCLE	Denton	TX	76203	237232618	501(c) 3	$10,000	$0	UTeach
WKU Research Foundation
1906 COLLEGE HEIGHTS BLVD	Bowling Green	KY	42101	611358086	501 (c) 3	$10,000	$0	UTeach
Drexel University
3141 CHESNUT ST	Philadelphia	PA	19104	231352630	501 (c) 3	$15,000	$0	UTeach

Field	Value	IRS element (for citing)
Total501c3 Org	81	Total501c3OrgCnt
Total Other Org	4	TotalOtherOrgCnt

Grants Other Asst To Indiv In US GrantsOtherAsstToIndivInUSGrp (6 entries)

Grant TypeGrantTypeTxt	RecipientRecipientCnt	Cash GrantCashGrantAmt
EXROP PROGRAM	105	$597,563
GILLIAM FELLOWSHIPS	92	$4,382,406
SCIENCE EDUCATION FELLOWSHIPS	1	$61,919
INTERNATIONAL PREDOCTORAL FELLOWSHIPS	85	$1,963,500
MEDICAL RESEARCH FELLOWSHIPS	70	$2,893,560
FACULTY SCHOLARS	80	$76,500,000

Supplemental Information Detail SupplementalInformationDetail

Field	Value	IRS element (for citing)
Form And Line Reference	Schedule I, Part I, Line 2 Procedures for monitoring use of grant funds.	FormAndLineReferenceDesc
Explanation	HHMI awards institutional grants in support of precollege, undergraduate, and graduate education in the US through periodic national competitions for which select institutions are eligible to apply. Each program sets out specific criteria and objectives, proposals are evaluated by a panel of experts with the final selection made by HHMI leadership. The Institute also awards fellowships to international predoctoral students, to medical students seeking to conduct basic laboratory research, and to doctoral students (the Gilliam Fellows). These grants are also awarded on a competitive basis. A small number of grants are awarded based on direct application to HHMI for specific initiatives directly related to science education. The disbursement of funds occurs principally through biomedical research institutions, universities, and colleges. HHMI grantees are required to file annual progress reports that detail expenditures in accordance with the terms of the grant, as well as full description of program activities undertaken with the funds. These are subject to careful review and analysis by HHMI staff with more detailed review by the Institute auditors as warranted. The Institute continues to assess reporting requirements to ensure the quality and timeliness of both financial and programmatic reports. In addition to site visits made by HHMI staff, program directors meet on a regular basis to discuss their activities and share information about best educational practices.	ExplanationTxt

Schedule J IRS990ScheduleJ

Field	Value	IRS element (for citing)
First Class Or Charter Travel	Yes (X)	FirstClassOrCharterTravelInd
Housing Allowance Or Residence	Yes (X)	HousingAllowanceOrResidenceInd
Written Policy Ref T And E Expnss	Yes (true)	WrittenPolicyRefTAndEExpnssInd
Substantiation Required	Yes (true)	SubstantiationRequiredInd
Compensation Committee	Yes (X)	CompensationCommitteeInd
Independent Consultant	Yes (X)	IndependentConsultantInd
Form990 Of Other Organizations	Yes (X)	Form990OfOtherOrganizationsInd
Written Employment Contract	Yes (X)	WrittenEmploymentContractInd
Compensation Survey	Yes (X)	CompensationSurveyInd
Board Or Committee Approval	Yes (X)	BoardOrCommitteeApprovalInd
Severance Payment	Yes (true)	SeverancePaymentInd
Supplemental Nonqual Rtr Plan	false	SupplementalNonqualRtrPlanInd
Equity Based Comp Arrngm	false	EquityBasedCompArrngmInd
Comp Based On Revenue Of Flng Org	false	CompBasedOnRevenueOfFlngOrgInd
Comp Bsd On Rev Related Orgs	false	CompBsdOnRevRelatedOrgsInd
Comp Bsd Net Earns Flng Org	false	CompBsdNetEarnsFlngOrgInd
Comp Bsd Net Earns Rltd Orgs	false	CompBsdNetEarnsRltdOrgsInd
Any Non Fixed Payments	Yes (true)	AnyNonFixedPaymentsInd
Initial Contract Exception	Yes (true)	InitialContractExceptionInd
Rebuttable Presumption Proc	Yes (true)	RebuttablePresumptionProcInd

Rltd Org Officer Trst Key Empl RltdOrgOfficerTrstKeyEmplGrp (23 entries)

TitleTitleTxt	Base Compensation Filing OrgBaseCompensationFilingOrgAmt	Compensation Based On Rltd OrgsCompensationBasedOnRltdOrgsAmt	Bonus Filing OrganizationBonusFilingOrganizationAmount	Bonus Related OrganizationsBonusRelatedOrganizationsAmt	Other Compensation Filing OrgOtherCompensationFilingOrgAmt	Other Compensation Rltd OrgsOtherCompensationRltdOrgsAmt	Deferred Compensation Flng OrgDeferredCompensationFlngOrgAmt	Deferred Comp Rltd OrgsDeferredCompRltdOrgsAmt	Nontaxable Benefits Filing OrgNontaxableBenefitsFilingOrgAmt	Nontaxable Benefits Rltd OrgsNontaxableBenefitsRltdOrgsAmt	Total Compensation Filing OrgTotalCompensationFilingOrgAmt	Total Compensation Rltd OrgsTotalCompensationRltdOrgsAmt	Comp Report Prior990 Filing OrgCompReportPrior990FilingOrgAmt	Comp Report Prior990 Rltd OrgsCompReportPrior990RltdOrgsAmt
LANDIS ZIMMERMAN
VP & CHIEF INVESTMENT OFFICER	$920,705	$0	$2,668,499	$0	$22,020	$0	$26,500	$0	$30,131	$0	$3,667,855	$0	$0	$0
LAUREN T SPILIOTES ESQ
DEP GENCOUNSEL/ASST SEC	$362,685	$0	$0	$0	$19,566	$0	$26,500	$0	$23,052	$0	$431,803	$0	$0	$0
SUSAN S PLOTNICK
ASSISTANT TREASURER & DIRECTOR-FINANCE	$231,847	$0	$3,000	$0	$893	$0	$22,450	$0	$32,751	$0	$290,941	$0	$0	$0
MONIQUE L MARCUS
CONTROLLER	$182,548	$0	$0	$0	$663	$0	$17,930	$0	$27,717	$0	$228,858	$0	$0	$0
ROBERT TJIAN PHD
PRESIDENT	$1,321,750	$0	$10,000	$0	$32,627	$0	$26,500	$0	$45,744	$0	$1,436,621	$0	$0	$0
CHERYL A MOORE
EXECUTIVE VP & COO	$861,067	$0	$10,000	$0	$20,010	$0	$26,500	$0	$21,271	$0	$938,848	$0	$0	$0
SEAN B CARROLL PHD
VP FOR SCIENCE EDUCATION	$659,690	$0	$10,000	$0	$20,864	$0	$26,500	$0	$26,514	$0	$743,568	$0	$0	$0
HEIDI E HENNING ESQ
VP,GENERAL COUNSEL/SEC	$544,821	$0	$0	$0	$20,365	$0	$26,500	$0	$28,242	$0	$619,928	$0	$0	$0
NITIN V KOTAK
VP, CFO & TREASURER	$382,303	$0	$5,000	$0	$19,662	$0	$26,500	$0	$30,653	$0	$464,118	$0	$0	$0
ERIN K O'SHEA PHD
VP & CHIEF SCI OFF	$654,777	$0	$10,000	$0	$88,584	$0	$26,500	$0	$19,098	$0	$798,959	$0	$0	$0
GERALD M RUBIN PHD
VP&EXEC DIR,JANELIA RES CAMPUS	$716,769	$0	$0	$0	$27,716	$0	$26,500	$0	$96,662	$0	$867,647	$0	$0	$0
KATHY WYSZYNSKI
VP, HUMAN RESOURCES	$255,841	$0	$5,000	$0	$19,087	$0	$26,232	$0	$14,300	$0	$320,460	$0	$0	$0
RICHARD A PENDER
MAN DIR - US EQUITIES	$484,903	$0	$471,092	$0	$20,097	$0	$26,500	$0	$27,210	$0	$1,029,802	$0	$0	$0
ROBERT J KOLYER JR
MAN DIR - DIVERSIFIED ASSETS	$425,254	$0	$1,013,297	$0	$20,841	$0	$26,500	$0	$28,273	$0	$1,514,165	$0	$0	$0
MARK A BARNARD
MAN DIR - PRIVATE EQUITIES	$397,407	$0	$860,310	$0	$22,765	$0	$26,500	$0	$31,903	$0	$1,338,885	$0	$0	$0
STEPHEN M KITSOULIS
MAN DIR - FIXED INCOME	$395,673	$0	$505,731	$0	$1,615	$0	$26,500	$0	$20,698	$0	$950,217	$0	$0	$0
GREGORY DENINNO
MAN DIR - PRIVATE EQUITIES	$246,813	$0	$337,799	$0	$2,653	$0	$24,742	$0	$32,254	$0	$644,261	$0	$0	$0
ANIL MADHOK
MAN DIR - INVESTMENTS & COO	$344,377	$0	$756,177	$0	$18,289	$0	$26,500	$0	$14,531	$0	$1,159,874	$0	$0	$0
DONALD KOCH
MAN DIR - PORTFOLIO STRATEGY	$285,829	$0	$674,527	$0	$18,264	$0	$26,500	$0	$32,024	$0	$1,037,144	$0	$0	$0
THOMAS R CECH PHD
INVESTIGATOR	$604,112	$0	$0	$0	$25,618	$0	$26,500	$0	$25,758	$0	$681,988	$0	$0	$0
RYAN L MATNEY
DIRECTOR-DIVERSIFIED ASSETS	$246,409	$0	$338,909	$0	$18,250	$0	$26,019	$0	$30,267	$0	$659,854	$0	$0	$0
ERIC R KANDEL MD
SENIOR INVESTIGATOR	$569,338	$0	$0	$0	$27,567	$0	$26,500	$0	$31,934	$0	$655,339	$0	$0	$0
MOHAMOUD JIBRELL
VP FOR INFORMATION TECHNOLOGY	$179,094	$0	$0	$0	$141,126	$0	$125,994	$0	$32,635	$0	$478,849	$0	$0	$0

Supplemental Information Detail SupplementalInformationDetail (5 entries)

Form And Line ReferenceFormAndLineReferenceDesc	ExplanationExplanationTxt
Schedule J, Part I, Line 1a First-class or charter travel	Under HHMI policies, HHMI reimburses its Trustees, President, Vice Presidents, and certain advisory group members for the reasonable cost of airfare at one class above coach for domestic or international flights of three hours or more. If a particular aircraft does not have a business class section, one class above coach may be first class. In this case HHMI would reimburse the traveling Trustee or officer for the reasonable cost of first-class travel if the flight is three hours or more. As an alternative, HHMI may reimburse for the cost of coach airfare plus the cost of an upgrade to travel at one level above coach for a flight of three hours or more. Such travel reimbursements are excluded from taxable compensation in accordance with HHMI's accountable plan. During fiscal year 2016, one key employee, two officers and one trustee flew first class.
Schedule J, Part I, Line 1a Housing allowance or residence for personal use	In fiscal year 2016, HHMI's President resided in an HHMI-owned apartment on the headquarters campus, for which he paid HHMI at a fair market rental rate. Because HHMI's President was also required to spend time at HHMI's Janelia campus, where he ran a research laboratory as well as attended meetings and participated in conferences, HHMI made a one-bedroom apartment available to him at that location. HHMI's Vice President and Executive Director, Janelia Research Campus, is required as a condition of employment to reside on the Janelia campus in housing built for that purpose. HHMI's Vice President and Chief Scientific Officer currently resides in an HHMI-owned house on the headquarters campus, for which she pays HHMI at a fair market rental rate. The Institute provides a housing assistance program for one individual who relocated to take a position with HHMI, which may be used to cover such individuals' mortgage or rent payments. In each case, the subsidy is treated as additional taxable compensation.
Schedule J, Part I, Line 4a Severance or change-of-control payment	VP for Information Technology - Total severance of $230,160 reported as compensation on Schedule J, Part II (B) iii of $130,666 and reported as deferred compensation on Schedule J, Part II (C) of $99,494.
Schedule J, Part I, Line 7 Non-fixed payments	HHMI has an incentive compensation plan for its senior investment staff under which a portion of their compensation is determined based on performance of HHMI's portfolio against market benchmarks. HHMI also makes one-time payments to some of its other employees, including but not limited to officers, in recognition of exceptional performance.
Schedule J, Part I, Line 8 Payments on contract that is subject to the initial contract exception	When recruiting individuals for high-level positions, HHMI typically enters into initial contracts. HHMI has entered into initial contracts with its President and a number of Vice Presidents. HHMI's standard practice is to have independent compensation consultants regularly review and confirm the reasonableness of compensation of HHMI's officers and key employees, regardless of whether the initial contract exception applies.

Schedule K IRS990ScheduleK

Tax Exempt Bonds Issues TaxExemptBondsIssuesGrp (4 entries)

Bond ReferenceBondReferenceCd	Bond Issuer EINBondIssuerEIN	CUSIPCUSIPNum	Bond IssuedBondIssuedDt	Issue PriceIssuePriceAmt	PurposePurposeDesc	DefeasedDefeasedInd	On Behalf Of IssuerOnBehalfOfIssuerInd	Pool FinancingPoolFinancingInd
LOUDOUN COUNTY IDA
A	521310230	545910AL5	2003-02-27	$500,000,000	FINANCE CONSTRUCTION OF JANELIA RESEARCH CAMPUS	false	false	false
LOUDOUN COUNTY IDA
B	521310230	545910AP6	2009-10-02	$23,000,000	FINANCE CONSTRUCTION OF JANELIA APT	false	false	false
LOUDOUN COUNTY IDA
C	521310230	545910AQ4	2013-05-15	$33,130,000	FINANCE CONSTRUCTION OF JANELIA APT B	false	false	false
MEDCO
D	521376562	574205FY1	2008-02-15	$83,500,000	FINANCE CONSTRUCTION OF HQ EXPANSION	false	false	false

Tax Exempt Bonds Proceeds TaxExemptBondsProceedsGrp (4 entries)

Bond ReferenceBondReferenceCd	RetiredRetiredAmt	Bond DefeasedBondDefeasedAmt	Total ProceedsTotalProceedsAmt	In Reserve FundInReserveFundAmt	Capitalized InterestCapitalizedInterestAmt	Refunding EscrowRefundingEscrowAmt	Issuance Costs From ProceedsIssuanceCostsFromProceedsAmt	Credit EnhancementCreditEnhancementAmt	Working Capital ExpendituresWorkingCapitalExpendituresAmt	Capital ExpendituresCapitalExpendituresAmt	Other Spent ProceedsOtherSpentProceedsAmt	UnspentUnspentAmt	Substantial CompletionSubstantialCompletionYr	Current RefundingCurrentRefundingInd	Advance RefundingAdvanceRefundingInd	Final Allocation MadeFinalAllocationMadeInd	Adequate Books And Rec MaintAdequateBooksAndRecMaintInd
A	$0	$0	$534,028,000	$0	$54,203,000	$0	$200,000	$0	$0	$479,625,000	$0	$0	2006	false	false	Yes (true)	Yes (true)
B	$0	$0	$23,022,042	$0	$904,914	$0	$0	$0	$43,305	$22,073,823	$0	$0	2011	false	false	Yes (true)	Yes (true)
C	$0	$0	$33,145,417	$0	$1,173,864	$0	$397,311	$0	$0	$31,574,242	$0	$0	2015	false	false	Yes (true)	Yes (true)
D	$0	$0	$84,953,297	$0	$5,954,687	$0	$631,673	$0	$0	$78,366,937	$0	$0	2010	false	false	Yes (true)	Yes (true)

Tax Exempt Bonds Private Bus Use TaxExemptBondsPrivateBusUseGrp (4 entries)

Bond ReferenceBondReferenceCd	Owning Bond Financed PropertyOwningBondFinancedPropertyInd	Any Lease ArrangementsAnyLeaseArrangementsInd	Mgmt Contract Bond Fincd PropMgmtContractBondFincdPropInd	Engage Bond Counsel ContractsEngageBondCounselContractsInd	Any Research AgreementsAnyResearchAgreementsInd	Engage Bond Counsel ResearchEngageBondCounselResearchInd	Bond Iss Meet Prvt Sec Pymt TestBondIssMeetPrvtSecPymtTestInd	Change In Use Bond Financed PropChangeInUseBondFinancedPropInd	Procs Nonqualified Bond RemdtdProcsNonqualifiedBondRemdtdInd
A	false	false	Yes (true)	Yes (true)	Yes (true)	Yes (true)	false	false	false
B	false	false	Yes (true)	Yes (true)	false		false	false	false
C	false	false	Yes (true)	Yes (true)	false		false	false	false
D	false	false	Yes (true)	Yes (true)	false		false	false	false

Tax Exempt Bonds Arbitrage TaxExemptBondsArbitrageGrp (4 entries)

Bond ReferenceBondReferenceCd	Form8038 T FiledForm8038TFiledInd	Variable Rate IssueVariableRateIssueInd	Hedge Identified In Bks And RecHedgeIdentifiedInBksAndRecInd	Term Of HedgeTermOfHedgePct	Superintegrated HedgeSuperintegratedHedgeInd	Hedge TerminatedHedgeTerminatedInd	Gross Proceeds Invested In GICGrossProceedsInvestedInGICInd	Gross Proceeds InvestedGrossProceedsInvestedInd	Written Proc To Monitor ReqsWrittenProcToMonitorReqsInd	Rebate Not Due YetRebateNotDueYetInd	Exception To RebateExceptionToRebateInd	No Rebate DueNoRebateDueInd
WELLS FARGO
A	Yes (true)	Yes (true)	Yes (true)	20.0	false	false	false	false	Yes (true)
JPMORGAN CHASE
B	false	Yes (true)	Yes (true)	30.0	false	false	false	false	Yes (true)	false	false	Yes (true)
WELLS FARGO BANK
C	false	Yes (true)	Yes (true)	30.0	false	false	false	false	Yes (true)	Yes (true)
JP MORGAN
D	false	Yes (true)	Yes (true)	30.0	false	false	false	false	Yes (true)	false	false	Yes (true)

Procedures Corrective Action ProceduresCorrectiveActionGrp (4 entries)

Bond ReferenceBondReferenceCd	Procedures Corrective ActionProceduresCorrectiveActionInd
A	false
B	false
C	false
D	false

Supplemental Information Detail SupplementalInformationDetail (6 entries)

Form And Line ReferenceFormAndLineReferenceDesc	ExplanationExplanationTxt
Schedule K, Part I Part I	The bond issued February 27, 2003 also includes CUSIPS 545910AM3, 545910AG6, 545910AH4, 545910AJO, and 545910AK7.
Schedule K, Part II, Line 3 Part II, Line 3 - Total Proceeds	The bonds issued on 2/27/2003, 10/2/2009, 2/15/2008 and 5/15/2013 included interest income that made up the difference between the amount of the bond issue and the total proceeds.
Schedule K, Part IV Part IV - Name of Provider	For the bond issued on 2/27/2003 $375 million notional amount of the $500 million notional amount of swaps pertaining to this bond were integrated. The other counterparties pertaining to the bond issued on 2/27/2003 were Bank of America (30 years), Goldman Sachs (30 years) and JP Morgan (30 years.)
Schedule K, Part IV, Line 4a Part IV, Line 4a	Yes, In part for the bonds issued on 2/27/2003, 10/2/2009, 2/15/2008, 5/15/2008 and 5/15/2013.
Schedule K, Part IV, Line 2c COLUMN B	Issuer name: LOUDOUN COUNTY IDA The calculation for computing no rebate due was performed on 10/08/2014
Schedule K, Part IV, Line 2c COLUMN D	Issuer name: MEDCO The calculation for computing no rebate due was performed on 02/12/2013

Schedule K IRS990ScheduleK

Tax Exempt Bonds Issues TaxExemptBondsIssuesGrp

Field	Value	IRS element (for citing)
Bond Reference	A	BondReferenceCd

Issuer Name IssuerName

Field	Value	IRS element (for citing)
Business Name Line1	MEDCO	BusinessNameLine1Txt

Field	Value	IRS element (for citing)
Bond Issuer EIN	521376562	BondIssuerEIN
CUSIP	574205FZ8	CUSIPNum
Bond Issued	2008-05-15	BondIssuedDt
Issue Price	$76,500,000	IssuePriceAmt
Purpose	REFUNDING OF ISSUE TO FINANCE HQ CONSTRUCTION	PurposeDesc
Defeased	false	DefeasedInd
On Behalf Of Issuer	false	OnBehalfOfIssuerInd
Pool Financing	false	PoolFinancingInd

Tax Exempt Bonds Proceeds TaxExemptBondsProceedsGrp

Field	Value	IRS element (for citing)
Bond Reference	A	BondReferenceCd
Retired	$0	RetiredAmt
Bond Defeased	$0	BondDefeasedAmt
Total Proceeds	$76,500,000	TotalProceedsAmt
In Reserve Fund	$0	InReserveFundAmt
Capitalized Interest	$0	CapitalizedInterestAmt
Refunding Escrow	$0	RefundingEscrowAmt
Issuance Costs From Proceeds	$0	IssuanceCostsFromProceedsAmt
Credit Enhancement	$0	CreditEnhancementAmt
Working Capital Expenditures	$0	WorkingCapitalExpendituresAmt
Capital Expenditures	$0	CapitalExpendituresAmt
Other Spent Proceeds	$76,500,000	OtherSpentProceedsAmt
Unspent	$0	UnspentAmt
Substantial Completion	1993	SubstantialCompletionYr
Current Refunding	Yes (true)	CurrentRefundingInd
Advance Refunding	false	AdvanceRefundingInd
Final Allocation Made	Yes (true)	FinalAllocationMadeInd
Adequate Books And Rec Maint	Yes (true)	AdequateBooksAndRecMaintInd

Tax Exempt Bonds Private Bus Use TaxExemptBondsPrivateBusUseGrp

Field	Value	IRS element (for citing)
Bond Reference	A	BondReferenceCd
Private Bus Use By Others	0.0	PrivateBusUseByOthersPct
Private Bus Concerning UBI	0.0	PrivateBusConcerningUBIPct
Total Private Business Use	0.0	TotalPrivateBusinessUsePct

Tax Exempt Bonds Arbitrage TaxExemptBondsArbitrageGrp

Field	Value	IRS element (for citing)
Bond Reference	A	BondReferenceCd
Form8038 T Filed	Yes (true)	Form8038TFiledInd
Variable Rate Issue	Yes (true)	VariableRateIssueInd
Hedge Identified In Bks And Rec	Yes (true)	HedgeIdentifiedInBksAndRecInd

Hedge Provider Name HedgeProviderName

Field	Value	IRS element (for citing)
Business Name Line1	GOLDMAN SACHS	BusinessNameLine1Txt

Field	Value	IRS element (for citing)
Term Of Hedge	30.0	TermOfHedgePct
Superintegrated Hedge	false	SuperintegratedHedgeInd
Hedge Terminated	false	HedgeTerminatedInd
Gross Proceeds Invested In GIC	false	GrossProceedsInvestedInGICInd
Gross Proceeds Invested	false	GrossProceedsInvestedInd
Written Proc To Monitor Reqs	Yes (true)	WrittenProcToMonitorReqsInd

Procedures Corrective Action ProceduresCorrectiveActionGrp

Field	Value	IRS element (for citing)
Bond Reference	A	BondReferenceCd
Procedures Corrective Action	false	ProceduresCorrectiveActionInd

Schedule O IRS990ScheduleO

Supplemental Information Detail SupplementalInformationDetail (11 entries)

Form And Line ReferenceFormAndLineReferenceDesc	ExplanationExplanationTxt
Form 990, Part III, Line 4a Program Service Description (continued)	(C) HIGHLIGHTS FROM HHMI RESEARCH LABORATORIES (FISCAL YEAR 2016) 1) Study Examines Scale of Gene Mutations in Human Neurons Christopher Walsh, Boston Children's Hospital https://www.hhmi.org/news/study-examines-scale-gene-mutations-human-neurons A single neuron in a normal adult brain likely has more than a thousand genetic mutations that are not present in the cells that surround it, according to research from HHMI scientists. The majority of these mutations appear to arise while genes are in active use, after brain development is complete. 2) High-Speed Microscope Images Entire Living Organisms at High Resolution Philipp Keller, Janelia Research Campus https://www.hhmi.org/news/seeing-big-picture A microscope developed at HHMI's Janelia Research Campus is giving scientists a clearer, more comprehensive view of biological processes as they unfold in living animals. The microscope produces images of entire organisms, such as a zebrafish or fruit fly embryo, with enough resolution in all three dimensions that each cell appears as a distinct structure. What's more, it does so at speeds fast enough to watch cells move as a developing embryo takes shape and to monitor brain activity as it flashes through neuronal circuits. 3) Researchers Identify New Factors that Guide Organization of Plant Roots Philip Benfey, Duke University https://www.hhmi.org/news/researchers-identify-new-factors-guide-organization-plant-roots As the root of a growing plant pushes its way through soil, its cells have a lot of organizing to do. New cells must take on the appropriate identities and positions to form distinct layers of tissue that give the root its structure, protect it from the environment, and ensure that it can properly transport materials to and from the rest of the plant. HHMI scientists have identified a set of proteins that plays a surprisingly broad role in guiding this tissue formation. The factors, known as the BIRDs, help a root maintain its organization as it grows, guiding several distinct steps in the development of two interior layers of tissue. 4) New Studies Advance Understanding of CRISPR Gene Editing Jennifer Doudna, University of California, Berkeley Robert Tjian, HHMI https://www.hhmi.org/news/new-studies-advance-understanding-crispr-gene-editing CRISPR/Cas9, a defense system that bacteria use to protect against invading genetic elements, was adapted by scientists in 2012 as tool to edit genomes in the lab. The new technology has been adopted enthusiastically by the research community because of its ability to cleave target sequences of DNA with remarkable precision and efficiency. After directly watching individual Cas9 enzymes explore DNA inside living cells, HHMI scientists report that they have a better understanding of how Cas9 speeds through this task, testing out potential targets but quickly moving on from those that are not an exact match. 5) Mutations Before Birth Might Disrupt Heart and Nervous System Development Christine Seidman, Brigham and Women's Hospital Richard Lifton, Yale University https://www.hhmi.org/news/mutations-birth-might-disrupt-heart-and-nervous-system-development A team of scientists has determined why some children who are born with heart defects also often have developmental disabilities such as problems with speech or muscle coordination. The research suggests that these children accrue mutations very early in development that damage genes crucial for heart and brain formation. About one percent of newborns suffer from congenital heart disease, in which structural flaws in the organ, such as misshapen valves or abnormal connections between major vessels, disrupt blood circulation. With surgery or less invasive procedures, doctors can now correct defects that would have killed many of these children 30 years ago. 6) Made in the Shade: How Plants Can Beat the Competition Joanne Chory, The Salk Institute for Biological Studies https://www.hhmi.org/news/made-shade-how-plants-can-beat-competition HHMI research has uncovered a molecular mechanism that enables plants to detect when they are in the shade of other plants and adapt by speeding up their growth. The scientists found that light-sensing and DNA-binding proteins team up to switch on a unique set of genes that cause a plant to grow. 7) Breakable Genes May Promote Disease and Brain Cell Diversity Frederick Alt, Boston Children's Hospital https://www.hhmi.org/news/breakable-genes-may-promote-disease-and-brain-cell-diversity HHMI researchers have identified 27 genes in brain stem cells that are prone to a type of DNA damage. The fragility of those genes could explain why they are often mutated or deleted in cancers and neuropsychiatric disorders such as schizophrenia. But their tendency to break could also benefit the brain by providing a way to produce a greater diversity of neurons. 8) New Studies Examine How Mice Respond to a Predator's Scent Linda Buck, Fred Hutchinson Cancer Research Center https://www.hhmi.org/news/new-studies-examine-how-mice-respond-predator-s-scent When the twitching pink nose of a mouse detects danger, the animal has to act fast. Fortunately, a predator rapidly triggers the release of stress hormones in the mouse and prompts behaviors that reduce the risk of it becoming the predator's latest snack. HHMI scientists have identified a brain area that is critical to this instinctive fear response, helping explain how the brain translates danger signals detected by the nose into a physiological response. The research offers clues to the larger puzzle of how animals, including humans, perceive and respond to fear. 9) Command and Control System Monitors Food Intake of Flies Leslie Vosshall, The Rockefeller University https://www.hhmi.org/news/command-and-control-system-monitors-food-intake-flies Working in fruit flies, HHMI scientists have discovered a command center in the brain that controls how much insects eat and how quickly they consume their food. To make the decision, neurons in the command center integrate information about an animal's internal state of satiety with taste cues detected just moments after food is swallowed. These neurons simultaneously monitor how hungry the fly is and what the fly is ingesting. Rapid feedback from the cells helps ensure that the insects consume appropriate amounts of nourishing foods. 10) Learning How the Brain Recovers from Disruptions Karel Svoboda and Shaul Druckmann, Janelia Research Campus https://www.hhmi.org/news/learning-how-brain-recovers-disruptions Scientists at HHMI's Janelia Research Campus have found that the brain is organized into modules that work together to maintain critical functions, even in the face of disturbances. This structural organization may explain how neurons that store short-term memories can recover from significant disruptions-for example, enabling a quarterback to remember a planned play despite the distractions he encounters before he throws the football. This organizational motif is likely to underlie other essential circuitry within the brain as well. 11) The Genetic History of Ice Age Europe David Reich, Harvard University https://www.hhmi.org/news/genetic-history-ice-age-europe Analyses of ancient DNA from prehistoric humans paint a picture of dramatic population change in Europe from 45,000 to 7,000 years ago. The new genetic data reveal two big changes in prehistoric human populations that are closely linked to the end of the last Ice Age around 19,000 years ago. As the ice sheet retreated, Europe was repopulated by prehistoric humans from southwest Europe (e.g., Spain). Then, in a second event about 14,000 years ago, populations from the southeast (e.g., Turkey, Greece) spread into Europe, displacing the first group of humans. 12) Staying a Step Ahead of Cancer Kevan Shokat, University of California, San Francisco https://www.hhmi.org/news/staying-step-ahead-cancer HHMI scientists have designed a potential cancer therapy that uses a unique strategy to block mTOR, a molecule that helps drive the growth of many tumors. In animal experiments, the drug reduces the size of tumors that are resistant to earlier-generation cancer drugs called mTOR inhibitors. 13) Molecule Required for Pain Also Helps Regulate Body Weight Scott Sternson, Janelia Research Campus https://www.hhmi.org/news/molecule-required-pain-also-helps-regulate-body-weight A molecule best known for its involvement in pain perception also plays an important role in regulating body weight, according to new research in mice by scientists at HHMI's Janelia Research Campus. The molecule, called Nav1.7, enables some neurons to efficiently integrate information they receive over time. When weight-regulating neurons lose this ability, mice become either over- or underweight.
Form 990, Part III, Line 4b Program Service Description (continued)	(C) Educational Media HHMI's Educational Media Group is comprised of BioInteractive and Tangled Bank Studios. BioInteractive, a resource for AP biology and college-level introductory biology teachers, has been in existence for more than 15 years and receives 2.5 million unique visitors per year through its website. The Educational Media Group produces science education resources including interactive multimedia materials, scientific animations, videos, in-class activities, the annual Holiday Lectures on Science, as well as award-winning, broadcast-quality short films. The products are then made available to educators online, through the BioInteractive.org website and YouTube channel, and at workshops and conventions. The 2015 Holiday Lectures on Science featured speakers, Robert M Pringle and Corina E Tarnita both from Princeton University, who discussed the "Patterns and Processes in Ecology." The speakers delivered their lectures live to an audience of about 150 high school students from the Washington, DC area. They described their efforts to understand patterns and processes that organize and regulate natural ecosystems. Their lectures were also made available online and will be supplemented by a variety of educational resources, including two "Scientist at Work" videos showing Silliman and Power conducting their research in salt marshes and rivers, respectively. This year, HHMI's Educational Media Group has continued to expand its efforts in translating its educational materials into Spanish and conducting professional development workshops for teachers in Latin American countries in collaboration with the Instituto de Neurociencia Biomedica (BNI), Universidad de Chile, and the Tecnologico de Monterrey, Mexico. The Spanish resources are currently available on the BioInteractive website and on Loligo, a new Spanish-language science education website produced by BNI. HHMI's Educational Media Group also expanded its efforts into citizen science. This year the group launched an educational addition to WildCam Gorongosa, its popular citizen science project that invites participants to identify animals in photos taken by motion-activated trail cameras at Gorongosa National Park (GNP). The new educational tool, called WildCam Lab, allows educators to create virtual classrooms in which students can ask questions and test hypotheses using data from the trail camera project. Students can select subsets of photos according to different criteria, download and sort through data, and share their work with other student. HHMI's Educational Media Group has also started planning a second citizen science project based in Darien National Park in Panama. Finally, HHMI's Educational Media Group will be launching an exciting new app, called BiomeViewer, in which users can explore the climate, vegetation, and wildlife of biomes across the globe. BiomeViewer builds on the success of the popular EarthViewer app which has been downloaded over 1.8 million times. (D) Tangled Bank Studios Tangled Bank Studios, LLC, HHMI's documentary film production unit, is dedicated to the creation of original science documentaries for broadcast, theatrical, and digital distribution. As an extension of HHMI's longstanding science education mission, the company aims to produce programs that capture compelling stories of discovery across all branches of scientific inquiry, with particular focus on the life sciences. Tangled Bank Studios won its first Emmy award, honoring the 2014 three-part PBS series Your Inner Fish. The show won in the Outstanding Graphic Design & Art Direction category in the 37th News & Documentary Emmy Awards competition. Your Inner Fish was a 2014 television series based on the best-selling book by leading paleontologist and evolutionary biologist Neil Shubin, a professor at the University of Chicago. In taking viewers on a cutting-edge, scientific adventure, Your Inner Fish reveals a startling truth: hidden within the human body is a history of life on Earth. Tangled Bank Studios has also produced Mass Extinction-Life at the Brink (Smithsonian Channel 2014) and Vaccines-Calling the Shots (PBS/NOVA 2014). New films released this year: In a new one-hour documentary, WGBH Boston's NOVA team partnered with HHMI's Tangled Bank Studios and Holt Productions to develop, Can Alzheimer's Be Stopped? The film premiered in April 2016 on PBS. Despite the urgent need for treatment, dozens of drug trials to tackle Alzheimer's disease have failed. Less than one percent of Alzheimer's drugs tested have been approved, and none of them can stop the disease. Can Alzheimer's Be Stopped? takes viewers behind the scenes of drug trials to reveal how they are designed, what makes them so challenging, and why researchers are encouraged in their quest for an effective treatment. Spillover - Zika, Ebola & Beyond premiered on PBS in August 2016. Throughout the last few decades, diseases that spill over from animals to humans have been on the rise. What's behind their increase, and can we do anything to combat these dangerous foes? The film follows scientists as they investigate the rise of spillover viruses like Zika, Ebola and Nipah, and learn what science can do to anticipate and prevent epidemics around the world. (E) eLife - Open Access Journal HHMI, together with the Wellcome Trust and the Max Planck Society, continues to support a top tier scientific journal called eLife. The online journal follows an open access model and is directed by practicing scientists. eLife Sciences Publications, Ltd., is an independent non-profit entity governed by a separate board of directors. eLife began publishing research articles in late 2012 and is publishing articles online on a regular basis.
Form 990, Part III, Line 4a Program Service Description (continued-1)	14) Extensive Variation Revealed in 1001 Genomes and Epigenomes of Arabidopsis Joseph Ecker, The Salk Institute for Biological Studies https://www.hhmi.org/news/extensive-variation-revealed-1001-genomes-and-epigenomes-arabidopsis An international team of scientists has sequenced the whole genomes and epigenomes of more than 1,000 Arabidopsis thaliana plants, sampled from geographically diverse locations. The collection of 1,001 genomes and 1,001 epigenomes not only illuminates new aspects of the plant's evolutionary history, but also provides a comprehensive, species-wide picture of the interaction between genetic and epigenetic variation in this important model plant. 15) Large Protein Nanocages Could Improve Drug Design and Delivery David Baker, University of Washington https://www.hhmi.org/news/large-protein-nanocages-could-improve-drug-design-and-delivery Using novel computational and biochemical approaches, scientists have accurately designed and built from scratch 10 large protein icosahedra -- polyhedra with 20 faces -- similar to viral capsids that carry viral DNA. The designed structures are made of two different engineered proteins, present in 60 copies each, which self-assemble into icosahedra. They have a wide variety of potential applications, from targeted drug delivery to the development of more effective vaccines, the researchers say. 16) Gene Tweak Leads to Differences in Drosophila Courtship Songs David Stern, Janelia Research Campus https://www.hhmi.org/news/love-me-do-gene-tweak-leads-differences-drosophila-courtship-songs Pinpointing the precise relationship between genes and behavior has been notoriously tricky for biologists. Janelia Research Campus scientists have devised new strategies to drill down into this link. Using new technologies, a group of Janelia scientists has identified a gene that causes male Drosophila to produce different courtship songs - one sings a high note; the other strikes a low note. The researchers hope the findings and methodology will serve as a roadmap for biologists, allowing them to determine other genetic roots of behavior. (D) Honors and Awards Received by HHMI Scientists (Fiscal Year 2016) Elledge Shares Lasker Award The Albert and Mary Lasker Foundation selected HHMI investigator Stephen Elledge of Brigham and Women's Hospital and Evelyn Witkin of Rutgers University as recipients of the 2015 Albert Lasker Basic Medical Research Award. The Lasker Awards -- considered among the most respected science prizes in the world -- honor visionaries whose insight and perseverance have led to dramatic advances that will prevent disease and prolong life. Elledge and Witkin were honored for discoveries concerning the DNA-damage response -- a fundamental mechanism that protects the genomes of all living organisms. Doudna Receives Canada's Gairdner Award for Research on CRISPR The Gairdner Foundation announced that HHMI Investigator Jennifer Doudna of the University of California, Berkeley is a recipient of the prestigious 2016 Canada Gairdner International Award in recognition of her contributions to medical science. The awards, which are presented annually, recognize scientists responsible for some of the world's most significant medical discoveries. Doudna, who became an HHMI investigator in 1997, was honored for development of CRISPR-Cas9 as a genome-editing tool for eukaryotic cells. HHMI Scientists Elected to The Royal Society HHMI investigators Mark Davis and Jennifer Doudna have been elected to foreign membership in the Royal Society in recognition of their exceptional contributions to science. Fellows and foreign members are elected for contributions to fundamental research as well as for leading scientific and technological progress in industry and research establishments. This year, 50 fellows and 10 foreign members were elected. Deisseroth and Hobbs Awarded Breakthrough Prizes The Breakthrough Prize Foundation selected HHMI investigators Karl Deisseroth of Stanford University and Helen Hobbs of the University of Texas Southwestern Medical Center as recipients of the Breakthrough Prizes in Life Sciences. The prizes honor transformative advances toward understanding living systems and extending human life. Deisseroth was honored for the development and implementation of optogenetics - the programming of neurons to express light-activated ion channels and pumps, so that their electrical activity can be controlled by light. Hobbs was recognized for the discovery of human genetic variants that alter the levels and distribution of cholesterol and other lipids, inspiring new approaches to the prevention of cardiovascular and liver disease. The Breakthrough Prizes recognize pioneering work in physics and genetics, cosmology, and neurology and mathematics. Each prize carries an award of $3 million. Zoghbi Awarded Shaw Prize The Shaw Prize Foundation in Hong Kong announced that Huda Zoghbi, a Howard Hughes Medical Institute investigator at Baylor College of Medicine, and Adrian Bird of the University of Edinburgh will share the $1.2 million award for their discovery of the genes and proteins involved in the developmental disorder Rett syndrome. The Shaw Prize consists of three annual awards in astronomy, life science and medicine, and mathematical sciences. These international awards honor individuals who have achieved distinguished breakthroughs in academic and scientific research. The awards are dedicated to furthering societal progress, enhancing quality of life, and enriching humanity's spiritual civilization. Five HHMI Researchers Elected to National Academy of Medicine Five HHMI researchers have been elected to the National Academy of Medicine (NAM). The HHMI scientists are among 70 new NAM members and 10 international members elected today. Established originally as the Institute of Medicine in 1970 by the National Academy of Sciences, the National Academy of Medicine addresses critical issues in health, science, medicine, and related policy and inspires positive actions across sectors. The new members are HHMI investigators, Michael Green, University of Massachusetts School of Medicine; Nikola Pavletich, Memorial Sloan Kettering Cancer Center; Alexander Rudensky, Memorial Sloan Kettering Cancer Center; Jean-Laurent Casanova, The Rockefeller University; and HHMI Senior International Research Scholar, Nahum Sonenberg, McGill University. HHMI Scientists Elected to National Academy of Sciences Eleven Howard Hughes Medical Institute scientists were elected to membership in the National Academy of Sciences. They are among 84 new members and 21 foreign associates from 15 countries elected in recognition of their distinguished and continuing achievements in original research. The National Academy of Sciences is a private organization of scientists and engineers dedicated to the furtherance of science and its use for the general welfare. The scientists are Joseph DeRisi, University of California, San Francisco; Raymond Deshaies, California Institute of Technology; Nathaniel Heintz, The Rockefeller University; Hopi Hoekstra, Harvard University; Kenneth Murphy, Washington University in St. Louis; Krishna Niyogi, University of California, Berkeley; David Sabatini, Whitehead Institute for Biomedical Research; Amita Sehgal, University of Pennsylvania; Geraldine Seydoux, The Johns Hopkins University; Michael Summers, University of Maryland, Baltimore County; Bonnie Bartel, Rice University.
Form 990, Part VI, Line 11b Review of form 990 by governing body	The Howard Hughes Medical Institute's Form 990 is initially prepared by its Tax Compliance Department, in coordination with other HHMI departments as needed. The draft return is reviewed by senior management of HHMI and by attorneys in HHMI's Office of the General Counsel. Following these reviews and the resolution of any questions that have been raised, the draft return is reviewed by HHMI's outside tax preparer. Finally, a copy of the return is provided to the members of HHMI's Board of Trustees so that they have an opportunity to review and comment on the return before it is filed.
Form 990, Part VI, Line 12c Conflict of interest policy	In addition to HHMI's code of conduct, which addresses conflicts of interest and applies to all HHMI employees, officers, Trustees, and advisors, HHMI has specific conflict of interest policies for different categories of personnel. Under the HHMI policies that apply to Trustees, officers, and key employees, these individuals must disclose annually interests that could give rise to conflicts of interest, and must certify annually their compliance with the conflict of interest policy that applies to them. Annual disclosures and certifications are reviewed by HHMI's Office of the General Counsel, and by other HHMI managers as needed. The conflict of interest policy covering HHMI's Trustees also requires each Trustee to disclose to the other Trustees any actual or apparent conflict of interest with respect to a proposed HHMI transaction. If the other Trustees decide that there is only the appearance of a conflict of interest, and that it could not reasonably be considered to affect the independent, unbiased judgment of the disclosing Trustee with respect to the transaction at issue, no further action is required to address the apparent conflict. In all other cases, including all actual conflicts of interest, the disclosing Trustee is not permitted to participate in the deliberation or decision regarding the transaction under consideration, and must leave the room during the deliberation and vote. The conflict of interest policies covering HHMI's officers and key employees require each covered individual to obtain supervisory approval up to the level of HHMI's President before entering into an affiliation with or acquiring an interest of 1% or more in any entity that is or may become a recipient of HHMI funds. HHMI's President, in consultation with HHMI's General Counsel, may permit the affiliation or interest if it would not interfere with the covered individual's performance of his or her HHMI responsibilities, would not create the appearance of a conflict of interest, and would be consistent with sound business judgment. HHMI's President may set conditions on approval, for example that there be no remuneration to the covered individual. Proposed affiliations and interests of 1% or more of HHMI's President are subject to the approval of the Chairman of the Trustees.
Form 990, Part VI, Line 15a Process to establish compensation of top management official	The compensation for HHMI's President, other officers, and key employees is set using the following procedures: Every other year, the Audit and Compensation Committee of HHMI's Board of Trustees engages one or more independent compensation consultants to conduct a study of comparable market data. The study includes data for HHMI's President, other officers, and key employees. The independent compensation consultants also provide an opinion regarding the reasonableness of the compensation arrangements for the positions included in the study. The study includes comparable market data for all components of compensation for each person covered by the study, including base salary, incentive compensation (if any), and benefits. The Committee relies on the market data and opinion provided by the compensation consultant in making recommendations to the Board of Trustees regarding compensation for HHMI's President, other officers and key employees. The decision is made by independent Trustees. Any Trustee who has a conflict of interest with respect to a specific officer or key employee must recuse himself or herself from the decision on that person's compensation, and leave the meeting room during the debate and voting on it. In the alternate years when a study is not done, the Audit and Compensation Committee confirms with the independent compensation consultants that the range of any proposed merit increases for HHMI employees, including senior management, is reasonable compared with generally prevailing compensation increases in the market over the past year. The Committee relies on this advice in recommending compensation for HHMI's President, other officers and key employees, and the Board of Trustees relies on this advice in making compensation decisions. Recusal procedures are the same as in the years when a study is done. In each year, minutes of the discussions and decisions regarding compensation are prepared after each meeting and are submitted for approval at the next meeting. Approved minutes are kept in HHMI's records. All minutes include the date of the meeting, identify those Trustees who attended and voted on the compensation arrangements, and note any recusals of Trustees with a conflict of interest. The comparability studies and opinions relied on at the meeting are referenced in the minutes, and copies of these materials are also kept in HHMI's records. HHMI's Board of Trustees followed this process in August 2015 in determining compensation for the following positions for fiscal year 2016: President, Vice Presidents, and Managing Directors - Investments.
Form 990, Part VI, Line 15b Process to establish compensation of other employees	The compensation for HHMI's President, other officers, and key employees is set using the following procedures: Every other year, the Audit and Compensation Committee of HHMI's Board of Trustees engages one or more independent compensation consultants to conduct a study of comparable market data. The study includes data for HHMI's President, other officers, and key employees. The independent compensation consultants also provide an opinion regarding the reasonableness of the compensation arrangements for the positions included in the study. The study includes comparable market data for all components of compensation for each person covered by the study, including base salary, incentive compensation (if any), and benefits. The Committee relies on the market data and opinion provided by the compensation consultant in making recommendations to the Board of Trustees regarding compensation for HHMI's President, other officers and key employees. The decision is made by independent Trustees. Any Trustee who has a conflict of interest with respect to a specific officer or key employee must recuse himself or herself from the decision on that person's compensation, and leave the meeting room during the debate and voting on it. In the alternate years when a study is not done, the Audit and Compensation Committee confirms with the independent compensation consultants that the range of any proposed merit increases for HHMI employees, including senior management, is reasonable compared with generally prevailing compensation increases in the market over the past year. The Committee relies on this advice in recommending compensation for HHMI's President, other officers and key employees, and the Board of Trustees relies on this advice in making compensation decisions. Recusal procedures are the same as in the years when a study is done. In each year, minutes of the discussions and decisions regarding compensation are prepared after each meeting and are submitted for approval at the next meeting. Approved minutes are kept in HHMI's records. All minutes include the date of the meeting, identify those Trustees who attended and voted on the compensation arrangements, and note any recusals of Trustees with a conflict of interest. The comparability studies and opinions relied on at the meeting are referenced in the minutes, and copies of these materials are also kept in HHMI's records. HHMl's Board of Trustees followed this process in August 2015 in determining compensation for the following positions for fiscal year 2016: President, Vice Presidents, and Managing Directors - Investments.
Form 990, Part VI, Line 19 Required documents available to the public	HHMI's practice has been to make a copy of its charter and by-laws available on request. HHMI's code of conduct, which addresses conflicts of interest, is available to the public on the HHMI website. A downloadable copy of HHMI's most recent audited financial statements is also available to the public on the website. In addition, HHMI publishes "Year in Review" that provides a summary of each year's activity, expenditures, and financial performance.
Form 990, Part VIII, Line 11d Other Miscellaneous Revenue	Miscellaneous - Total Revenue: 313443, Related or Exempt Function Revenue: , Unrelated Business Revenue: , Revenue Excluded from Tax Under Sections 512, 513, or 514: 313443; Innovation Dissemination - Total Revenue: 117362, Related or Exempt Function Revenue: , Unrelated Business Revenue: , Revenue Excluded from Tax Under Sections 512, 513, or 514: 117362;
Schedule A, Part I, Line 4 List of Hospital Affiliations	List of hospital affiliations for e-filing: Hospital, City, State, Zip Code- B&W Hospital, Boston, MA, 02115/ Children's Hosp, Boston, MA, 02115/ Children's Hosp, Cincinnati, OH, 45229/ Dana-Farber, Boston, MA, 02115/ Fred Hutch, Seattle, WA, 98109/ JHopkins Hosp, Baltimore, MD, 21205/ Mass Gen Hosp, Boston, MA, 02129/ MSKCC, New York, NY, 10021/ Nat'l Jewish, Denver, CO, 80206/ St Jude, Memphis, TN, 38105/ Duke-Duke Hosp, Durham, NC, 27706/ NYU-NYU Hosps, New York, NY, 10016/ OHSU-OHSU Hosp, Portland, OR, 97239/ Rockefeller-Hosp, New York, NY,10021/ Penn State Univ-Hosp, University Park, PA 16802/ Stanford-Hosp, Palo Alto, CA, 94305/ UCLA-Med Ctr, Los Angeles, CA, 90095/ UCSD-Med Ctr, San Diego, CA, 92093/ UCSF-UCSF Hosps, San Francisco, CA, 94143/ UIowa-UIowa Hosps, Iowa City, IA, 52242/ UMass-Med Ctr, Worcester, MA, 01605/ UMich-UMich Hosp, Ann Arbor, MI, 48109/ UPenn-UPenn Hosp, Philadelphia, PA, 19104/ UT-Austin-UT Hosp, Austin, TX, 78712/ UTSW-UTSW Hosps, Dallas, TX, 75390/ UUtah-UUtah Hosps, Salt Lake City, UT, 84112/ UWash-Med Ctr, Seattle, WA, 98195/ ADARC-aff hosp, New York, NY, 10016/ AECOM-affil hosps, New York, NY, 10461/ Baylor-aff hosps, Houston, TX, 77O3O/ BU-aff hosp, Boston, MA, 02126/ Brandeis-aff hsps, Waltham, MA, 02254/ CalTech-aff hosps, Pasadena, CA, 91125/ Carnegie-aff hsps, Baltimore, MD, 21210/ CSHL-affil hosps, Cold Spring Harbor, NY, 11724/ CSU-affil hosp, Fort Collins, CO, 80521/ Columbia-aff hsps, New York, NY, 10027/ Cornell-aff hosps, New York, NY, 14853/ Harvard-aff hosps, Cambridge, MA, 02138/ Indiana-affil hosp, Bloomington, IN, 47405/ TJL-affil hosps, Bar Harbor, ME, 04609/ JHU-affil hosps, Baltimore, MD, 21218/ MichSU-affil hosps, Lansing, MI, 48824/ MIT-affil hosps, Boston, MA, 02139/ NWU-affil hosps, Evanston, IL, 60208/ Princeton-aff hosps, Princeton, NJ, 08544/ Rutgers-affil hosp, Piscataway, NJ, 08854/ Salk-affil hosps ,La Jolla, CA, 92093/ Scripps-affil hosps, La Jolla, CA 92037/ Stowers-aff hosps, Kansas City, MO, 64110/ SUNY-affil hosps, Stony Brook, NY,11794/ Texas A&M-aff hsp, College Station, TX, 77843/ Tufts-aff hosps, Boston, MA, 02111/ UCB-affil hosps, Berkeley, CA, 94720/ UCDavis-affil hsps, Davis, CA, 95616/ UCR-affil hosps, Riversde, CA, 92521/ UCSC-aff hosps, Santa Cruz, CA, 95064/ UChi-affil hosp, Chicago, IL, 60637/ UColo-aff hosp, Boulder, CO, 80309/ UColo-aff hosp, Denver, CO, 80217/ Uillinois-aff hsp, Urbana, IL, 61801/ UMD-affil hosp, Baltimore, MD, 21201/ UMN-affil hosp, Minneapolis, MN 55414/ UNC-affil hosps, Chapel Hill, NC, 27599/ UOregon-aff hsp, Eugene, OR,97403/ UWisc-affil hosps, Madison, WI, 53706/ WashU-aff hosp, St Louis, MO, 63130/ YaleU-affil hosp, New Haven, CT, 06520/
Schedule A, Part I, Line 4 MRO Qualification	The Institute is a medical research organization for its taxable year ended August 31, 2016, as its expenditures of $ 791,795,075 on a cash basis for the year ended August 31 , 2015 exceeded the MRO requirement of $727,119,083 (3.5% of the HHMI endowment).

Schedule R IRS990ScheduleR

Id Disregarded Entities IdDisregardedEntitiesGrp (52 entries)

Address Line1USAddress/AddressLine1Txt	CityUSAddress/CityNm	State AbbreviationUSAddress/StateAbbreviationCd	ZIPUSAddress/ZIPCd	Primary ActivitiesPrimaryActivitiesTxt	Legal Domicile StateLegalDomicileStateCd	Total IncomeTotalIncomeAmt	End Of Year AssetsEndOfYearAssetsAmt	Business Name Line1DirectControllingEntityName/BusinessNameLine1Txt	EINEIN	Address Line1ForeignAddress/AddressLine1Txt	Province Or StateForeignAddress/ProvinceOrStateNm	CountryForeignAddress/CountryCd	Foreign PostalForeignAddress/ForeignPostalCd	Legal Domicile Foreign CountryLegalDomicileForeignCountryCd
HHMI II LLC
4000 JONES BRIDGE ROAD	CHEVY CHASE	MD	20815	INVESTMENT	DE	$7,482,899	$515,652,860	HHMI
HHMI IV LLC
4000 JONES BRIDGE ROAD	CHEVY CHASE	MD	20815	INVESTMENT	DE	$0	$0	HHMI
HHMI V LLC
4000 JONES BRIDGE ROAD	CHEVY CHASE	MD	20815	INVESTMENT	DE	$0	$0	HHMI
HHMI XII LLC
4000 JONES BRIDGE ROAD	CHEVY CHASE	MD	20815	INVESTMENT	DE	$0	$0	HHMI
HHMI XVI LLC
4000 JONES BRIDGE ROAD	CHEVY CHASE	MD	20815	INVESTMENT	DE	-$7,196,998	$369,516,766	HHMI
SPRUGOS INVESTMENTS II LLC
4000 JONES BRIDGE ROAD	CHEVY CHASE	MD	20815	INVESTMENT	DE	$0	$0	HHMI
SPRUGOS INVESTMENTS V LLC
4000 JONES BRIDGE ROAD	CHEVY CHASE	MD	20815	INVESTMENT	DE	$8,776,795	$61,472,990	HHMI
SPRUGOS INVESTMENTS VII LLC
4000 JONES BRIDGE ROAD	CHEVY CHASE	MD	20815	INVESTMENT	DE	$28,076,355	$229,778,026	HHMI
SPRUGOS INVESTMENTS VIII LLC
4000 JONES BRIDGE ROAD	CHEVY CHASE	MD	20815	INVESTMENT	DE	$33,383,422	$218,197,977	HHMI
SPRUGOS INVESTMENTS X LLC
4000 JONES BRIDGE ROAD	CHEVY CHASE	MD	20815	INVESTMENT	DE	$0	$0	HHMI
SPRUGOS INVESTMENTS XI LLC
4000 JONES BRIDGE ROAD	CHEVY CHASE	MD	20815	INVESTMENT	DE	$22,917,767	$70,480,415	HHMI
SPRUGOS INVESTMENTS XII LLC
4000 JONES BRIDGE ROAD	CHEVY CHASE	MD	20815	INVESTMENT	DE	$8,943	$108,933	HHMI
SPRUGOS INVESTMENTS XIII LLC
4000 JONES BRIDGE ROAD	CHEVY CHASE	MD	20815	INVESTMENT	DE	$0	$0	HHMI
PRIVATE EQUITY HOLDING LLC
4000 JONES BRIDGE ROAD	CHEVY CHASE	MD	20815	INVESTMENT	DE	$0	$0	HHMI
PRIVATE EQUITY HOLDING-AHEAD LLC
4000 JONES BRIDGE ROAD	CHEVY CHASE	MD	20815	INVESTMENT	DE	$394	$0	HHMI
PRIVATE EQUITY HOLDING-ALEXA LLC
4000 JONES BRIDGE ROAD	CHEVY CHASE	MD	20815	INVESTMENT	DE	-$2,593	$0	HHMI
PRIVATE EQUITY HOLDING-CS CAPITAL LLC
4000 JONES BRIDGE ROAD	CHEVY CHASE	MD	20815	INVESTMENT	DE	-$467,856	$0	HHMI
PRIVATE EQUITY HOLDING-EUROCASTLE LLC
4000 JONES BRIDGE ROAD	CHEVY CHASE	MD	20815	INVESTMENT	DE	-$360,168	$2,635,439	HHMI
PRIVATE EQUITY HOLDING-FAVRILLE LLC
4000 JONES BRIDGE ROAD	CHEVY CHASE	MD	20815	INVESTMENT	DE	$0	$0	HHMI
PRIVATE EQUITY HOLDING-KAP LLC
4000 JONES BRIDGE ROAD	CHEVY CHASE	MD	20815	INVESTMENT	DE	$0	$0	HHMI
PRIVATE EQUITY HOLDING-ROYCE LLC
4000 JONES BRIDGE ROAD	CHEVY CHASE	MD	20815	INVESTMENT	DE	$0	$0	HHMI
PRIVATE EQUITY HOLDING-STORERETRO LLC
4000 JONES BRIDGE ROAD	CHEVY CHASE	MD	20815	INVESTMENT	DE	$0	$0	HHMI
PRIVATE EQUITY HOLDING-XENOPORT LLC
4000 JONES BRIDGE ROAD	CHEVY CHASE	MD	20815	INVESTMENT	DE	$0	$0	HHMI
HHMI FI I LLC
4000 JONES BRIDGE ROAD	CHEVY CHASE	MD	20815	INVESTMENT	DE	$0	$0	HHMI
JANELIA FARM HOLDING LLC
4000 JONES BRIDGE ROAD	CHEVY CHASE	MD	20815	INVESTMENT	VA	$0	$0	HHMI
SELDEN ISLAND HOLDING LLC
4000 JONES BRIDGE ROAD	CHEVY CHASE	MD	20815	INVESTMENT	VA	$0	$0	HHMI
HHMI I LLC
4000 JONES BRIDGE ROAD	CHEVY CHASE	MD	20815	INVESTMENT	DE	$0	$0	HHMI
HHMI III LLC
4000 JONES BRIDGE ROAD	CHEVY CHASE	MD	20815	INVESTMENT	DE	$0	$0	HHMI
HHMI VI LLC
4000 JONES BRIDGE ROAD	CHEVY CHASE	MD	20815	INVESTMENT	DE	$0	$0	HHMI
HHMI VII LLC
4000 JONES BRIDGE ROAD	CHEVY CHASE	MD	20815	INVESTMENT	DE	-$787,782	$107,909,665	HHMI
HHMI VIII LLC
4000 JONES BRIDGE ROAD	CHEVY CHASE	MD	20815	INVESTMENT	DE	$0	$0	HHMI
HHMI IX LLC
4000 JONES BRIDGE ROAD	CHEVY CHASE	MD	20815	INVESTMENT	DE	$0	$0	HHMI
HHMI X LLC
4000 JONES BRIDGE ROAD	CHEVY CHASE	MD	20815	INVESTMENT	DE	$0	$0	HHMI
HHMI XI LLC
4000 JONES BRIDGE ROAD	CHEVY CHASE	MD	20815	INVESTMENT	DE	$0	$0	HHMI
HHMI XIII LLC
4000 JONES BRIDGE ROAD	CHEVY CHASE	MD	20815	INVESTMENT	DE	$0	$0	HHMI
HHMI XIV LLC
4000 JONES BRIDGE ROAD	CHEVY CHASE	MD	20815	INVESTMENT	DE	$0	$0	HHMI
HHMI XV LLC
4000 JONES BRIDGE ROAD	CHEVY CHASE	MD	20815	INVESTMENT	DE	$0	$0	HHMI
SPRUGOS INVESTMENTS LLC
4000 JONES BRIDGE ROAD	CHEVY CHASE	MD	20815	INVESTMENT	DE	$0	$0	HHMI
SPRUGOS INVESTMENTS III LLC
4000 JONES BRIDGE ROAD	CHEVY CHASE	MD	20815	INVESTMENT	DE	$17,380,556	$324,995,022	HHMI
SPRUGOS INVESTMENTS IV LLC
4000 JONES BRIDGE ROAD	CHEVY CHASE	MD	20815	INVESTMENT	DE	$0	$0	HHMI
SPRUGOS INVESTMENTS VI LLC
4000 JONES BRIDGE ROAD	CHEVY CHASE	MD	20815	INVESTMENT	DE	$0	$0	HHMI
SPRUGOS INVESTMENTS IX LLC
4000 JONES BRIDGE ROAD	CHEVY CHASE	MD	20815	INVESTMENT	DE	$10,396,721	$330,002,477	HHMI
SPRUGOS-FRENCH LLC
4000 JONES BRIDGE ROAD	CHEVY CHASE	MD	20815	INVESTMENT	DE	$0	$0	HHMI
PRIVATE EQUITY HOLDING II LLC
4000 JONES BRIDGE ROAD	CHEVY CHASE	MD	20815	INVESTMENT	DE	$0	$0	HHMI
PRIVATE EQUITY HOLDING III LLC
4000 JONES BRIDGE ROAD	CHEVY CHASE	MD	20815	INVESTMENT	DE	$0	$0	HHMI
RELATIVE VALUE STRATEGIES LLC
4000 JONES BRIDGE ROAD	CHEVY CHASE	MD	20815	INVESTMENT	DE	$0	$0	HHMI
PSG LLC
4000 JONES BRIDGE ROAD	CHEVY CHASE	MD	20815	INVESTMENT	DE	$0	$0	HHMI
HHMI-SA LLC
4000 JONES BRIDGE ROAD	CHEVY CHASE	MD	20815	RESEARCH	DE	$0	$161,606	HHMI
TANGLED BANK STUDIOS LLC
4000 JONES BRIDGE ROAD	CHEVY CHASE	MD	20815	FILM PROD	DE	$0	$0	HHMI
MISSING LINK PRODUCTIONS LLC
4000 JONES BRIDGE ROAD	CHEVY CHASE	MD	20815	FILM PROD	DE	$0	$126	HHMI	471329820
LSV ADVANTAGE INTL III (CAYMAN) LTD
				INVESTMENT		-$789,734	$27,196,419	HHMI	980689621	89 NEXUS WAY 2/F CANAMA BAY	GRAND CAYMAN	CJ	KY11205	CJ
LSV ADVANTAGE INTL III-B (CAYMAN) LTD
				INVESTMENT		$17,713,772	$97,058,358	HHMI	981087158	89 NEXUS WAY 2/F CAMANA BAY	GRAND CAYMAN	CJ	KY11205	CJ

Id Related Org Txbl Partnership IdRelatedOrgTxblPartnershipGrp (12 entries)

Address Line1ForeignAddress/AddressLine1Txt	CityForeignAddress/CityNm	CountryForeignAddress/CountryCd	Foreign PostalForeignAddress/ForeignPostalCd	EINEIN	Primary ActivitiesPrimaryActivitiesTxt	Legal Domicile Foreign CountryLegalDomicileForeignCountryCd	Business Name Line1DirectControllingEntityName/BusinessNameLine1Txt	Predominant Income TypePredominantIncomeTypeTxt	Share Of Total IncomeShareOfTotalIncomeAmt	Share Of EOY AssetsShareOfEOYAssetsAmt	Disproportionate AllocationsDisproportionateAllocationsInd	UBI Code VUBICodeVAmt	General Or Managing PartnerGeneralOrManagingPartnerInd	OwnershipOwnershipPct	Address Line1USAddress/AddressLine1Txt	Address Line2USAddress/AddressLine2Txt	CityUSAddress/CityNm	State AbbreviationUSAddress/StateAbbreviationCd	ZIPUSAddress/ZIPCd	Legal Domicile StateLegalDomicileStateCd	Province Or StateForeignAddress/ProvinceOrStateNm
CERBERUS HH PARTNERS LP
190 ELGIN AVENUE	GEORGETOWN	CJ	KY19005	981102879	INVESTMENT	CJ	HHMI	Excluded	$9,709,626	$142,748,880	false	$0	false	0.95
GEM NPL CO-INV FUND LP
				464232021	INVESTMENT		HHMI	Excluded	$2,241	$1,607,918	false	-$223,424	false	0.67	900 NORTH MICHIGAN AVENUE SUITE 14	SUITE 1450	CHICAGO	IL	60611	IL
HHLF LP
				462823996	INVESTMENT		HHMI	Excluded	$6,348,363	$31,437,374	false	$0	false	0.94	555 5TH AVENUE FL18		NEW YORK	NY	10017	NY
LUMINUS CREDIT OPPORTUNITIES PIE I LP
				261963557	INVESTMENT		HHMI	Excluded	$1,924,728	$45,845,840	false	$0	false	0.99	1700 BROADWAY 38TH FLOOR		NEW YORK	NY	10019	NY
SOLUS OPPORTUNITIES FUND 2 LP
				463541945	INVESTMENT		HHMI	Excluded	$7,354,072	$61,023,991	false	$0	false	0.98	410 PARK AVENUE 11TH FLOOR		NEW YORK	NY	10022	NY
CVI HH INVESTMENTS LP
				901010136	INVESTMENT		HHMI	Excluded	$3,175,407	$289,352,589	false	$0	false	1.0	9320 EXCELSIOR BLVD	MS144-7-2	HOPKINS	MN	55343	MN
ECHO STREET GOODCO SELECT II LP
				474827277	INVESTMENT		HHMI	Excluded	$2,364,778	$105,905,868	false	$0	false	1.0	10 EAST 53RD STREET	32ND FLOOR	NEW YORK	NY	10022	NY
GEM BVP CO-INV-A LP
				472251559	INVESTMENT		HHMI	Excluded	$0	$7,075,267	false	$0	false	1.0	900 NORTH MICHIGAN AVENUE	SUITE 1450	CHICAGO	IL	60611	IL
HH HOLDCO CO-INVESTMENT FUND LP
				300864915	INVESTMENT		HHMI	Excluded	$371,467	$69,391,381	false	$0	false	0.99478	32 BROADWAY SUITE 1201		NEW YORK	NY	10004	NY
HH SG SECONDARY FUND LP
				473358493	INVESTMENT		HHMI	Excluded	$1,490,738	$15,847,917	false	$0	false	0.94	825 THIRD AVENUE	10TH FLOOR	NEW YORK	NY	10022	NY
TOURMALET MATAWIN OFFSHORE FUND VI-A LP
89 NEXUS WAY CAMANA BAY		CJ	KY19007		INVESTMENT	CJ	HHMI	Excluded	$2,364,893	$35,066,543	false	$0	false	1.0							GRAND CAYMAN
HH ELLINGTON MASTER FUND LTD
				981020904	INVESTMENT		HHMI	Excluded	$12,566,556	$30,037,303	false	$0	false	0.82	53 FOREST AVENUE		OLD GREENWICH	CT	06870	CT

Id Related Org Txbl Corp Tr IdRelatedOrgTxblCorpTrGrp (12 entries)

Address Line1USAddress/AddressLine1Txt	CityUSAddress/CityNm	State AbbreviationUSAddress/StateAbbreviationCd	ZIPUSAddress/ZIPCd	EINEIN	Primary ActivitiesPrimaryActivitiesTxt	Legal Domicile StateLegalDomicileStateCd	Business Name Line1DirectControllingEntityName/BusinessNameLine1Txt	Entity TypeEntityTypeTxt	Share Of Total IncomeShareOfTotalIncomeAmt	Share Of EOY AssetsShareOfEOYAssetsAmt	OwnershipOwnershipPct	Controlled OrganizationControlledOrganizationInd	Address Line1ForeignAddress/AddressLine1Txt	Address Line2ForeignAddress/AddressLine2Txt	CityForeignAddress/CityNm	CountryForeignAddress/CountryCd	Legal Domicile Foreign CountryLegalDomicileForeignCountryCd	Province Or StateForeignAddress/ProvinceOrStateNm	Foreign PostalForeignAddress/ForeignPostalCd
HHMI REAL ESTATE INC
4000 JONES BRIDGE ROAD	CHEVY CHASE	MD	20815	203967202	INVESTMENT	DE	HHMI	C Corporation	$20,439	$1,668,550	1	Yes (true)
PLEASANT VALLEY INVESTMENTS LP
				980586696	INVESTMENT		HHMI	C Corporation	$4,608,493	$26,622,556	0.51	Yes (true)	99 QUEENS ROAD CENTRAL	UNIT 2112 21/F THE CENTER	HONG KONG	HK	CJ
HH ELLINGTON FUND LTD
					INVESTMENT		HHMI	C Corporation	$12,566,556	$30,037,303	1	Yes (true)	WALKER HOUSE 87 MARY STREET		GEORGETOWN	CJ	CJ	GR	KY19005
SPRUGOS MAURITIUS I LTD
					INVESTMENT		HHMI	C Corporation	$6,775,987	$29,127,898	1	Yes (true)	33 EDITH CAVELL STREET		PORT LOUIS	MP	MP
HHMI CAYMAN I COMPANY
					INVESTMENT		HHMI	C Corporation	-$24,913	$311,021	1	Yes (true)	WALKER WALKER HOUSE MARY STREET	PO BOX 265GT	GEORGETOWN	CJ	CJ
CHALKSTREAM KOREA FUND INTERNATIONAL LP
				981248058	INVESTMENT		HHMI	C Corporation	-$5,000,309	$44,624,449	1	Yes (true)	27 Hospital Road		George Town	CJ	CJ	Grand Cayman	KY19008
LSV ADVANTAGE INTERNATIONAL III LTD
				981300995	INVESTMENT		HHMI	C Corporation	$84,458	$3,982,159	1	Yes (true)	89 NEXUS WAY 2/F CAMANA BAY			CJ	CJ	GRAND CAYMAN	KY11205
LSV ADVANTAGE INTERNATIONAL III-B LTD
				981315328	INVESTMENT		HHMI	C Corporation	$2,420,501	$14,462,081	1	Yes (true)	89 NEXUS WAY 2/F CAMANA BAY			CJ	CJ	GRAND CAYMAN	KY11205
COASTLAND RELATIVE VALUE FUND LTD
					INVESTMENT		HHMI	C Corporation	$15,533,287	$97,841,370	0.7	Yes (true)	WALKER HOUSE 87 MARY STREET		GEORGE TOWN	CJ	CJ	GRAND CAYMAN	KY19005
IRONSIDES PARTNERS SPECIAL SITUATIONS OFFSHORE FUND LTD
					INVESTMENT		HHMI	C Corporation	$43,289	$9,887,435	0.58	Yes (true)	PO BOX 309 UGLAND HOUSE			CJ	CJ	GRAND CAYMAN	11104
MARSHALL WACE MANAGED ACCOUNTS PLC-MW EUROPA FUND II
					INVESTMENT		HHMI	C Corporation	$21,718,331	$168,665,556	1	Yes (true)	BEAUX LANE HOUSEMERCER ST LOWER		DUBLIN	EI	EI		2
NEWFOUNDLAND TERRANOVA OFFSHORE FUND
					INVESTMENT		HHMI	C Corporation	-$11,854,539	$111,953,942	0.82	Yes (true)	89 NEXUS WAY CAMANA BAY			CJ	CJ	GRAND CAYMAN	KY19007

Field	Value	IRS element (for citing)
Receipt Of Int Annts Rnts Rylts	false	ReceiptOfIntAnntsRntsRyltsInd
Gift Grnt Or Cap Contri To Oth Org	Yes (true)	GiftGrntOrCapContriToOthOrgInd
Gift Grnt Cap Contri From Oth Org	false	GiftGrntCapContriFromOthOrgInd
Loans Or Guarantees To Other Org	false	LoansOrGuaranteesToOtherOrgInd
Loans Or Guarantees From Oth Org	false	LoansOrGuaranteesFromOthOrgInd
Asset Sale To Other Org	false	AssetSaleToOtherOrgInd
Asset Purchase From Other Org	false	AssetPurchaseFromOtherOrgInd
Asset Exchange	false	AssetExchangeInd
Rental Of Facilities To Oth Org	false	RentalOfFacilitiesToOthOrgInd
Rental Of Fclts From Oth Org	false	RentalOfFcltsFromOthOrgInd
Perform Of Services For Oth Org	false	PerformOfServicesForOthOrgInd
Perform Of Services By Other Org	false	PerformOfServicesByOtherOrgInd
Sharing Of Facilities	false	SharingOfFacilitiesInd
Paid Employees Sharing	false	PaidEmployeesSharingInd
Reimbursement Paid To Other Org	false	ReimbursementPaidToOtherOrgInd
Reimbursement Paid By Other Org	false	ReimbursementPaidByOtherOrgInd
Transfer To Other Org	false	TransferToOtherOrgInd
Transfer From Other Org	Yes (true)	TransferFromOtherOrgInd

Transactions Related Org TransactionsRelatedOrgGrp (24 entries)

Transaction TypeTransactionTypeTxt	InvolvedInvolvedAmt	Method Of Amount DeterminationMethodOfAmountDeterminationTxt
CERBERUS HH PARTNERS LP
B	$33,998,371	FMV
CVI HH INVESTMENTS LP
B	$80,000,000	FMV
ECHO STREET GOODCO SELECT II LP
B	$100,000,000	FMV
GEM BVP CO-INV-A LP
B	$7,100,000	FMV
HH HOLDCO CO-INVESTMENT FUND LP
B	$83,665,150	FMV
HH SG SECONDARY FUND LP
B	$12,828,000	FMV
SPRUGOS MAURITIUS I LTD
B	$46,025,593	FMV
CHALKSTREAM KOREA FUND INTERNATIONAL LP
B	$25,000,000	FMV
LSV ADVANTAGE INTERNATIONAL III LTD
B	$389,848	FMV
LSV ADVANTAGE INTERNATIONAL III-B LTD
B	$3,043,059	FMV
CERBERUS HH PARTNERS LP
S	$3,864,734	FMV
GEM NPL CO-INV FUND LP
S	$4,351,644	FMV
HHLF LP
S	$43,054,472	FMV
SOLUS OPPORTUNITIES FUND 2 LP
S	$19,396,949	FMV
CVI HH INVESTMENTS LP
S	$36,000,000	FMV
HH HOLDCO CO-INVESTMENT FUND LP
S	$17,546,687	FMV
HH SG SECONDARY FUND LP
S	$3,498,963	FMV
SPRUGOS MAURITIUS I LTD
S	$90,596,188	FMV
HH ELLINGTON FUND LTD
S	$172,500,000	FMV
COASTLAND RELATIVE VALUE FUND LTD
S	$151,873,341	FMV
TOURMALET MATAWIN OFFSHORE FUND VI-A LP
B	$4,000,000	FMV
TOURMALET MATAWIN OFFSHORE FUND VI-A LP
S	$21,000,000	FMV
MARSHALL WACE MANAGED ACCOUNTS PLC-MW EUROPA FUND II
S	$15,000,000	FMV
IRONSIDES PARTNERS SPECIAL SITUATIONS OFFSHORE FUND LTD
S	$5,000,000	FMV