SCRIPPS RESEARCH INSTITUTE: Form 990, tax year 2024

View the entire original 990 at ProPublica ↗

Organization: SCRIPPS RESEARCH INSTITUTE (EIN 33-0435954)
Tax period: 2024-10-01 to 2025-09-30
Filed: 2026-07-15
IRS object ID: 202601969349301335
Schema version: 2024v5.5
Source: Download XML · Original 990 at ProPublica

Every field in the e-filed return. Faint text is the IRS element name, for citing.

Return header
Form 990
Schedule A
Schedule B
Schedule D
Schedule F
Schedule I
Schedule J
Schedule K
Schedule M
Schedule O
Schedule R

Return header ReturnHeader

Field	Value	IRS element (for citing)
Return	2026-07-15T09:37:09-05:00	ReturnTs
Tax Period End	2025-09-30	TaxPeriodEndDt

Preparer Firm PreparerFirmGrp

Field	Value	IRS element (for citing)
Preparer Firm EIN	861065772	PreparerFirmEIN

Preparer Firm Name PreparerFirmName

Field	Value	IRS element (for citing)
Business Name Line1	DELOITTE TAX LLP	BusinessNameLine1Txt

Preparer US Address PreparerUSAddress

Field	Value	IRS element (for citing)
Address Line1	111 MONUMENT CIRCLE SUITE 4200	AddressLine1Txt
City	INDIANAPOLIS	CityNm
State Abbreviation	IN	StateAbbreviationCd
ZIP	462045108	ZIPCd

Field	Value	IRS element (for citing)
Return Type	990	ReturnTypeCd
Tax Period Begin	2024-10-01	TaxPeriodBeginDt

Filer Filer

Field	Value	IRS element (for citing)
EIN	330435954	EIN

Business Name BusinessName

Field	Value	IRS element (for citing)
Business Name Line1	THE SCRIPPS RESEARCH INSTITUTE	BusinessNameLine1Txt

Field	Value	IRS element (for citing)
Business Name Control	SCRI	BusinessNameControlTxt
Phone	8587841000	PhoneNum

US Address USAddress

Field	Value	IRS element (for citing)
Address Line1	10550 NORTH TORREY PINES ROAD	AddressLine1Txt
City	LA JOLLA	CityNm
State Abbreviation	CA	StateAbbreviationCd
ZIP	92037	ZIPCd

Business Officer BusinessOfficerGrp

Field	Value	IRS element (for citing)
Person	JARED MACHADO	PersonNm
Person Title	CHIEF FINANCIAL OFFICER	PersonTitleTxt
Phone	8587849817	PhoneNum
Signature	2026-07-10	SignatureDt
Discuss With Paid Preparer	Yes (1)	DiscussWithPaidPreparerInd

Field	Value	IRS element (for citing)
IRS Responsible Prty Info Curr	Yes (1)	IRSResponsiblePrtyInfoCurrInd

Preparer Person PreparerPersonGrp

Field	Value	IRS element (for citing)
Preparer Person	SHAWNA M JANSONS	PreparerPersonNm
PTIN	P01222873	PTIN
Phone	3174648600	PhoneNum

Field	Value	IRS element (for citing)
Tax	2024	TaxYr
Build TS	2025-03-06 01:10:19Z	BuildTS

Form 990 IRS990

Field	Value	IRS element (for citing)
Principal Officer	PETER SCHULTZ PHD	PrincipalOfficerNm

US Address USAddress

Field	Value	IRS element (for citing)
Address Line1	10550 NORTH TORREY PINES ROAD	AddressLine1Txt
City	LA JOLLA	CityNm
State Abbreviation	CA	StateAbbreviationCd
ZIP	92037	ZIPCd

Field	Value	IRS element (for citing)
Gross Receipts	$1,358,708,093	GrossReceiptsAmt
Group Return For Affiliates	0	GroupReturnForAffiliatesInd
Organization501c3	Yes (X)	Organization501c3Ind
Website Address	WWW.SCRIPPS.EDU	WebsiteAddressTxt
Type Of Organization Corp	Yes (X)	TypeOfOrganizationCorpInd
Formation	1924	FormationYr
Legal Domicile State	CA	LegalDomicileStateCd
Activity Or Mission	TSRI CONDUCTS BIOMEDICAL AND BIOCHEMICAL RESEARCH AND POSTGRADUATE TRAINING PROGRAMS.	ActivityOrMissionDesc
Voting Members Governing Body	16	VotingMembersGoverningBodyCnt
Voting Members Independent	14	VotingMembersIndependentCnt
Total Employee	2022	TotalEmployeeCnt
Total Volunteers	14	TotalVolunteersCnt
Total Gross UBI	-$123,639	TotalGrossUBIAmt
Net Unrelated Bus Txbl Incm	$0	NetUnrelatedBusTxblIncmAmt
PY Contributions Grants	$370,268,955	PYContributionsGrantsAmt
CY Contributions Grants	$317,961,835	CYContributionsGrantsAmt
PY Program Service Revenue	$2,212,057	PYProgramServiceRevenueAmt
CY Program Service Revenue	$1,811,390	CYProgramServiceRevenueAmt
PY Investment Income	$30,267,045	PYInvestmentIncomeAmt
CY Investment Income	$36,569,701	CYInvestmentIncomeAmt
PY Other Revenue	$238,358,106	PYOtherRevenueAmt
CY Other Revenue	$342,281,392	CYOtherRevenueAmt
PY Total Revenue	$641,106,163	PYTotalRevenueAmt
CY Total Revenue	$698,624,318	CYTotalRevenueAmt
PY Grants And Similar Paid	$127,840,846	PYGrantsAndSimilarPaidAmt
CY Grants And Similar Paid	$117,089,363	CYGrantsAndSimilarPaidAmt
PY Benefits Paid To Members	$0	PYBenefitsPaidToMembersAmt
CY Benefits Paid To Members	$0	CYBenefitsPaidToMembersAmt
PY Salaries Comp Emp Bnft Paid	$203,451,715	PYSalariesCompEmpBnftPaidAmt
CY Salaries Comp Emp Bnft Paid	$202,849,110	CYSalariesCompEmpBnftPaidAmt
PY Total Prof Fndrsng Expns	$389,103	PYTotalProfFndrsngExpnsAmt
CY Total Prof Fndrsng Expns	$0	CYTotalProfFndrsngExpnsAmt
CY Total Fundraising Expense	$7,540,995	CYTotalFundraisingExpenseAmt
PY Other Expenses	$196,756,129	PYOtherExpensesAmt
CY Other Expenses	$217,515,508	CYOtherExpensesAmt
PY Total Expenses	$528,437,793	PYTotalExpensesAmt
CY Total Expenses	$537,453,981	CYTotalExpensesAmt
PY Revenues Less Expenses	$112,668,370	PYRevenuesLessExpensesAmt
CY Revenues Less Expenses	$161,170,337	CYRevenuesLessExpensesAmt
Total Assets BOY	$1,299,917,796	TotalAssetsBOYAmt
Total Assets EOY	$1,460,616,898	TotalAssetsEOYAmt
Total Liabilities BOY	$368,128,581	TotalLiabilitiesBOYAmt
Total Liabilities EOY	$306,765,344	TotalLiabilitiesEOYAmt
Net Assets Or Fund Balances BOY	$931,789,215	NetAssetsOrFundBalancesBOYAmt
Net Assets Or Fund Balances EOY	$1,153,851,554	NetAssetsOrFundBalancesEOYAmt
Info In Schedule O Part III	Yes (X)	InfoInScheduleOPartIIIInd
Mission	THE SCRIPPS RESEARCH INSTITUTE ("TSRI") PERFORMS HIGH IMPACT BASIC BIOMEDICAL RESEARCH, IMPROVES THE HUMAN CONDITION BY FOSTERING TRANSLATION OF ITS DISCOVERIES INTO USEFUL PRODUCTS AND ENGAGES IN THE HIGHEST QUALITY GRADUATE SCIENTIFIC EDUCATION AND POST GRADUATE SCIENTIFIC TRAINING. TSRI IS KNOWN FOR ITS ENTREPRENEURIAL ENVIRONMENT AND ITS EMPHASIS IN RESEARCH RELATING TO SYNTHETIC CHEMISTRY, THE RELATIONSHIP BETWEEN MOLECULAR STRUCTURE AND ACTIVITY AND CHEMICAL BIOLOGY.	MissionDesc
Significant New Program Srvc	0	SignificantNewProgramSrvcInd
Significant Change	0	SignificantChangeInd
Expense	$473,621,099	ExpenseAmt
Grant	$99,620,335	GrantAmt
Revenue	$9,803,187	RevenueAmt
Desc	GROUNDBREAKING SCIENTIFIC RESEARCH IS CONDUCTED AT TSRI CAMPUSES IN LA JOLLA, CALIFORNIA, SUPPORTED BY GRANTS, CONTRACTS AND FELLOWSHIPS FROM PUBLIC AND PRIVATE INSTITUTES AND INDIVIDUALS. TSRI'S UNIQUE STRUCTURE MERGES BASIC SCIENTIFIC STUDIES IN BIOLOGY, CHEMISTRY AND BIOINFORMATICS WITH TRANSLATIONAL SCIENCE TO PRODUCE THE NEXT GENERATION OF DRUGS AND ADVANCES IN DIGITAL AND PRECISION MEDICINE. SCIENTIFIC DISCOVERIES AT TSRI SEED JOINT DRUG DISCOVERY PROJECTS AT CALIBR-SKAGGS, A DIVISION OF TSRI, CREATING A PIPELINE OF DRUG CANDIDATES THAT WILL IMPACT PATIENTS FOR YEARS TO COME. THE SCRIPPS RESEARCH TRANSLATIONAL INSTITUTE, ANOTHER DIVISION OF TSRI, AIMS TO INDIVIDUALIZE HEALTHCARE BY LEVERAGING THE PROGRESS BEING MADE IN HUMAN GENOMICS AND COMBINING IT WITH THE POWER OF WIRELESS DIGITAL TECHNOLOGIES AND ARTIFICIAL INTELLIGENCE.	Desc

Prog Srvc Accom Acty2 ProgSrvcAccomActy2Grp

Field	Value	IRS element (for citing)
Expense	$20,835,219	ExpenseAmt
Grant	$17,469,028	GrantAmt
Desc	TSRI IS COMMITTED TO EDUCATING, TRAINING AND INSPIRING THE SCIENTISTS OF TOMORROW. THE INSTITUTE'S SKAGGS GRADUATE SCHOOL OF CHEMICAL AND BIOLOGICAL SCIENCES, RANKED ONE OF THE TEN BEST GRADUATE PROGRAMS IN THE COUNTRY, EMPOWERS STUDENTS TO MAKE HIGH-IMPACT DISCOVERIES AT THE INTERFACE OF CHEMISTRY AND BIOLOGY. STUDENTS IN THE SKAGGS GRADUATE SCHOOL ARE IMMERSED IN INTENSIVE LABORATORY RESEARCH FROM DAY ONE AND PURSUE AMBITIOUS INVESTIGATIONS ACROSS SCIENTIFIC DISCIPLINES. GRADUATES OF THE SCHOOL BECOME EDUCATORS AT TOP UNIVERSITIES AND RESEARCH INSTITUTES, THOUGHT LEADERS WITHIN GOVERNMENT DEPARTMENTS AND INNOVATORS AT PHARMACEUTICAL AND BIOTECHNOLOGY COMPANIES. POSTDOCTORAL ASSOCIATES ARRIVE AT TSRI FROM ALL OVER THE GLOBE, SEEKING TO EXPAND THEIR KNOWLEDGE AND TRAINING BY WORKING ALONGSIDE OUR WORLD-RENOWNED SCIENTISTS. THE SCRIPPS FELLOWS PROGRAM IDENTIFIES INDIVIDUALS WITH AN OUTSTANDING RECORD OF GRADUATE RESEARCH AND MOVES THEM INTO THEIR OWN LABORATORIES, ALLOWING THEM TO LEAPFROG THEIR POSTDOCTORAL YEARS OF STUDY AND BEGIN PUSHING THE FRONTIERS OF SCIENTIFIC DISCOVERY.	Desc

Field	Value	IRS element (for citing)
Total Program Service Expenses	$494,456,318	TotalProgramServiceExpensesAmt
Described In Section501c3	Yes (1)	DescribedInSection501c3Ind
Schedule B Required	Yes (1)	ScheduleBRequiredInd
Political Campaign Acty	0	PoliticalCampaignActyInd
Lobbying Activities	0	LobbyingActivitiesInd
Subject To Proxy Tax	0	SubjectToProxyTaxInd
Donor Advised Fund	0	DonorAdvisedFundInd
Conservation Easements	0	ConservationEasementsInd
Collections Of Art	0	CollectionsOfArtInd
Credit Counseling	0	CreditCounselingInd
Donor Rstr Or Quasi Endowments	Yes (1)	DonorRstrOrQuasiEndowmentsInd
Report Land Building Equipment	Yes (1)	ReportLandBuildingEquipmentInd
Report Investments Other Sec	Yes (1)	ReportInvestmentsOtherSecInd
Report Program Related Invst	0	ReportProgramRelatedInvstInd
Report Other Assets	0	ReportOtherAssetsInd
Report Other Liabilities	Yes (1)	ReportOtherLiabilitiesInd
Include FIN48 Footnote	0	IncludeFIN48FootnoteInd
Independent Audit Fincl Stmt	0	IndependentAuditFinclStmtInd
Consolidated Audit Fincl Stmt	Yes (1)	ConsolidatedAuditFinclStmtInd
School Operating	0	SchoolOperatingInd
Foreign Office	0	ForeignOfficeInd
Foreign Activities	Yes (1)	ForeignActivitiesInd
More Than5000 K To Org	Yes (1)	MoreThan5000KToOrgInd
More Than5000 K To Individuals	0	MoreThan5000KToIndividualsInd
Professional Fundraising	0	ProfessionalFundraisingInd
Fundraising Activities	0	FundraisingActivitiesInd
Gaming Activities	0	GamingActivitiesInd
Operate Hospital	0	OperateHospitalInd
Grants To Organizations	Yes (1)	GrantsToOrganizationsInd
Grants To Individuals	Yes (1)	GrantsToIndividualsInd
Schedule J Required	Yes (1)	ScheduleJRequiredInd
Tax Exempt Bonds	Yes (1)	TaxExemptBondsInd
Invest Tax Exempt Bonds	0	InvestTaxExemptBondsInd
Escrow Account	0	EscrowAccountInd
On Behalf Of Issuer	0	OnBehalfOfIssuerInd
Engaged In Excess Benefit Trans	0	EngagedInExcessBenefitTransInd
PY Excess Benefit Trans	0	PYExcessBenefitTransInd
Loan Outstanding	0	LoanOutstandingInd
Grant To Related Person	0	GrantToRelatedPersonInd
Business Rln With Org Mem	0	BusinessRlnWithOrgMemInd
Business Rln With Fam Mem	0	BusinessRlnWithFamMemInd
Business Rln With35 Ctrl Ent	0	BusinessRlnWith35CtrlEntInd
Deductible Non Cash Contri	Yes (1)	DeductibleNonCashContriInd
Deductible Art Contribution	0	DeductibleArtContributionInd
Terminate Operations	0	TerminateOperationsInd
Partial Liquidation	0	PartialLiquidationInd
Disregarded Entity	Yes (1)	DisregardedEntityInd
Related Entity	Yes (1)	RelatedEntityInd
Related Organization Ctrl Ent	Yes (1)	RelatedOrganizationCtrlEntInd
Transaction With Control Ent	Yes (1)	TransactionWithControlEntInd
Trnsfr Exmpt Non Chrtbl Rltd Org	0	TrnsfrExmptNonChrtblRltdOrgInd
Activities Conducted Prtshp	0	ActivitiesConductedPrtshpInd
Schedule O Required	Yes (1)	ScheduleORequiredInd
IRP Document	517	IRPDocumentCnt
IRP Document W2 G	0	IRPDocumentW2GCnt
Backup Wthld Compliance	Yes (1)	BackupWthldComplianceInd
Employee	2022	EmployeeCnt
Employment Tax Returns Filed	Yes (1)	EmploymentTaxReturnsFiledInd
Unrelated Bus Incm Over Limit	Yes (1)	UnrelatedBusIncmOverLimitInd
Form990 T Filed	Yes (1)	Form990TFiledInd
Foreign Financial Account	0	ForeignFinancialAccountInd
Prohibited Tax Shelter Trans	0	ProhibitedTaxShelterTransInd
Taxable Party Notification	0	TaxablePartyNotificationInd
Nondeductible Contributions	0	NondeductibleContributionsInd
Quid Pro Quo Contributions	0	QuidProQuoContributionsInd
Form8282 Property Disposed Of	0	Form8282PropertyDisposedOfInd
Rcv Fnds To Pay Prsnl Bnft Cntrct	0	RcvFndsToPayPrsnlBnftCntrctInd
Pay Premiums Prsnl Bnft Cntrct	0	PayPremiumsPrsnlBnftCntrctInd
Indoor Tanning Services	0	IndoorTanningServicesInd
Subj To Tax Rmnrtn Ex Prcht Pymt	Yes (1)	SubjToTaxRmnrtnExPrchtPymtInd
Subject To Excs Tax Net Invst Inc	0	SubjectToExcsTaxNetInvstIncInd
Info In Schedule O Part VI	Yes (X)	InfoInScheduleOPartVIInd
Governing Body Voting Members	16	GoverningBodyVotingMembersCnt
Independent Voting Member	14	IndependentVotingMemberCnt
Family Or Business Rln	0	FamilyOrBusinessRlnInd
Delegation Of Mgmt Duties	0	DelegationOfMgmtDutiesInd
Change To Org Documents	0	ChangeToOrgDocumentsInd
Material Diversion Or Misuse	0	MaterialDiversionOrMisuseInd
Members Or Stockholders	0	MembersOrStockholdersInd
Election Of Board Members	0	ElectionOfBoardMembersInd
Decisions Subject To Approva	0	DecisionsSubjectToApprovaInd
Minutes Of Governing Body	Yes (1)	MinutesOfGoverningBodyInd
Minutes Of Committees	Yes (1)	MinutesOfCommitteesInd
Officer Mailing Address	0	OfficerMailingAddressInd
Local Chapters	0	LocalChaptersInd
Form990 Provided To Gvrn Body	Yes (1)	Form990ProvidedToGvrnBodyInd
Conflict Of Interest Policy	Yes (1)	ConflictOfInterestPolicyInd
Annual Disclosure Covered Prsn	Yes (1)	AnnualDisclosureCoveredPrsnInd
Regular Monitoring Enfrc	Yes (1)	RegularMonitoringEnfrcInd
Whistleblower Policy	Yes (1)	WhistleblowerPolicyInd
Document Retention Policy	Yes (1)	DocumentRetentionPolicyInd
Compensation Process CEO	Yes (1)	CompensationProcessCEOInd
Compensation Process Other	Yes (1)	CompensationProcessOtherInd
Investment In Joint Venture	0	InvestmentInJointVentureInd
States Where Copy Of Return Is Fld	AK	StatesWhereCopyOfReturnIsFldCd
States Where Copy Of Return Is Fld	AR	StatesWhereCopyOfReturnIsFldCd
States Where Copy Of Return Is Fld	CA	StatesWhereCopyOfReturnIsFldCd
States Where Copy Of Return Is Fld	CO	StatesWhereCopyOfReturnIsFldCd
States Where Copy Of Return Is Fld	DC	StatesWhereCopyOfReturnIsFldCd
States Where Copy Of Return Is Fld	FL	StatesWhereCopyOfReturnIsFldCd
States Where Copy Of Return Is Fld	HI	StatesWhereCopyOfReturnIsFldCd
States Where Copy Of Return Is Fld	KS	StatesWhereCopyOfReturnIsFldCd
States Where Copy Of Return Is Fld	KY	StatesWhereCopyOfReturnIsFldCd
States Where Copy Of Return Is Fld	MA	StatesWhereCopyOfReturnIsFldCd
States Where Copy Of Return Is Fld	MD	StatesWhereCopyOfReturnIsFldCd
States Where Copy Of Return Is Fld	ME	StatesWhereCopyOfReturnIsFldCd
States Where Copy Of Return Is Fld	MI	StatesWhereCopyOfReturnIsFldCd
States Where Copy Of Return Is Fld	MS	StatesWhereCopyOfReturnIsFldCd
States Where Copy Of Return Is Fld	ND	StatesWhereCopyOfReturnIsFldCd
States Where Copy Of Return Is Fld	NH	StatesWhereCopyOfReturnIsFldCd
States Where Copy Of Return Is Fld	NJ	StatesWhereCopyOfReturnIsFldCd
States Where Copy Of Return Is Fld	NV	StatesWhereCopyOfReturnIsFldCd
States Where Copy Of Return Is Fld	NY	StatesWhereCopyOfReturnIsFldCd
States Where Copy Of Return Is Fld	OH	StatesWhereCopyOfReturnIsFldCd
States Where Copy Of Return Is Fld	OK	StatesWhereCopyOfReturnIsFldCd
States Where Copy Of Return Is Fld	OR	StatesWhereCopyOfReturnIsFldCd
States Where Copy Of Return Is Fld	RI	StatesWhereCopyOfReturnIsFldCd
States Where Copy Of Return Is Fld	SC	StatesWhereCopyOfReturnIsFldCd
States Where Copy Of Return Is Fld	WA	StatesWhereCopyOfReturnIsFldCd
Upon Request	Yes (X)	UponRequestInd

Books In Care Of Detail BooksInCareOfDetail

Business Name BusinessName

Field	Value	IRS element (for citing)
Business Name Line1	JARED MACHADO	BusinessNameLine1Txt

Field	Value	IRS element (for citing)
Phone	8587841000	PhoneNum

US Address USAddress

Field	Value	IRS element (for citing)
Address Line1	10550 N TORREY PINES DRIVE	AddressLine1Txt
City	LA JOLLA	CityNm
State Abbreviation	CA	StateAbbreviationCd
ZIP	92037	ZIPCd

Form990 Part VII Section A Form990PartVIISectionAGrp (29 entries)

TitleTitleTxt	Average Hours Per WeekAverageHoursPerWeekRt	Average Hours Per Week Rltd OrgAverageHoursPerWeekRltdOrgRt	Individual Trustee Or DirectorIndividualTrusteeOrDirectorInd	OfficerOfficerInd	Reportable Comp From OrgReportableCompFromOrgAmt	Reportable Comp From Rltd OrgReportableCompFromRltdOrgAmt	Other CompensationOtherCompensationAmt	Key EmployeeKeyEmployeeInd	Highest Compensated EmployeeHighestCompensatedEmployeeInd	Former Ofcr Director TrusteeFormerOfcrDirectorTrusteeInd
PETER G SCHULTZ
PRESIDENT/CEO	40.00	0.00	Yes (X)	Yes (X)	$1,784,580	$0	$74,660
BENJAMIN CRAVATT
FACULTY DIRECTOR (START 10/24)/PROF	40.00	0.00	Yes (X)		$390,594	$0	$39,791
ARDEM PATAPOUTIAN
FACULTY DIRECTOR (END 10/24)/PROF	9.20	0.00	Yes (X)		$142,661	$0	$0
JOHN D DIEKMAN
DIRECTOR/BOARD CHAIR	1.00	0.00	Yes (X)		$0	$0	$0
BARBARA KOSACZ
DIRECTOR	1.00	0.00	Yes (X)		$0	$0	$0
BENEDICT GROSS
DIRECTOR (END 10/24)	1.00	0.00	Yes (X)		$0	$0	$0
CLAUDIA S LUTTRELL
DIRECTOR	1.00	0.00	Yes (X)		$0	$0	$0
GENE LAY
DIRECTOR	1.00	0.00	Yes (X)		$0	$0	$0
GERALD CHAN
DIRECTOR	1.00	0.00	Yes (X)		$0	$0	$0
HERBERT WERTHEIM
DIRECTOR	1.00	0.00	Yes (X)		$0	$0	$0
LILLIAN LOU
DIRECTOR	1.00	0.00	Yes (X)		$0	$0	$0
LOU LANGE
DIRECTOR (START 10/24)	1.00	0.00	Yes (X)		$0	$0	$0
MARK EDWARDS
DIRECTOR	1.00	0.00	Yes (X)		$0	$0	$0
MARK PEARSON
DIRECTOR	1.00	0.00	Yes (X)		$0	$0	$0
PETER C FARRELL
DIRECTOR	1.00	0.00	Yes (X)		$0	$0	$0
RON BURKLE
DIRECTOR	1.00	0.00	Yes (X)		$0	$0	$0
SHERRY LANSING
DIRECTOR	1.00	0.00	Yes (X)		$0	$0	$0
TOM DANIEL
DIRECTOR	1.00	0.00	Yes (X)		$0	$0	$0
CAROLINE MOON
CFO	40.00	0.00		Yes (X)	$832,577	$0	$65,791
MARSHALL OLIN
GENERAL COUNSEL	40.00	0.00		Yes (X)	$672,211	$0	$74,166
JARED M MACHADO
TREASURER/CHIEF ACCOUNTING OFFICER	40.00	0.00		Yes (X)	$371,821	$0	$52,864
ALANNA RUTAN
SECRETARY/CHIEF COMPLIANCE COUNSEL	40.00	0.00		Yes (X)	$272,207	$0	$45,635
KELLY SAN GEORGE
CFO VP ADM. CALIBR	40.00	0.00			$453,276	$0	$68,490	Yes (X)
ERIC TOPOL
PROFESSOR/EXEC VP	24.00	0.00			$1,057,040	$0	$28,595		Yes (X)
SCOTT SHOWALTER
CHIEF ADVANCEMENT OFFICER	40.00	0.00			$707,626	$0	$37,224		Yes (X)
CHANNING R BEALS
CHIEF MEDICAL OFFICER	40.00	0.00			$601,637	$0	$83,905		Yes (X)
TRAVIS SCOTT YOUNG
SR. DIRECTOR, CALIBR	40.00	0.00			$537,630	$0	$69,099		Yes (X)
JING LI
SENIOR DIRECTOR	40.00	0.00			$478,912	$0	$55,304		Yes (X)
JAMES R WILLIAMSON
FRMR VP RES&ACAD AFFS(END 1/23)/PROF	40.00	0.00			$344,113	$0	$44,602			Yes (X)

Field	Value	IRS element (for citing)
Total Reportable Comp From Org	$8,646,885	TotalReportableCompFromOrgAmt
Tot Reportable Comp Rltd Org	$0	TotReportableCompRltdOrgAmt
Total Other Compensation	$740,126	TotalOtherCompensationAmt
Indiv Rcvd Greater Than100 K	380	IndivRcvdGreaterThan100KCnt
Former Ofcr Employees Listed	Yes (1)	FormerOfcrEmployeesListedInd
Total Comp Greater Than150 K	Yes (1)	TotalCompGreaterThan150KInd
Compensation From Other Srcs	Yes (1)	CompensationFromOtherSrcsInd

Contractor Compensation ContractorCompensationGrp (5 entries)

Address Line1ContractorAddress/USAddress/AddressLine1Txt	CityContractorAddress/USAddress/CityNm	State AbbreviationContractorAddress/USAddress/StateAbbreviationCd	ZIPContractorAddress/USAddress/ZIPCd	ServicesServicesDesc	CompensationCompensationAmt
KEKER VAN NEST & PETERS LLP
633 BATTERY ST	SAN FRANCISCO	CA	94111	LEGAL SERVICES	$4,408,569
UNIVERSAL PROTECTION SERVICES LP
PO BOX 31001-2374	PASADENA	CA	911102374	SECURITY SERVICES	$1,249,160
STRATEGIC INVESTMENT GROUP
1001 NINETEENTH STREET NORTH 16TH	ARLINGTON	VA	22209	INVESTMENT MANAGEMENT SERVICES	$947,691
DELOITTE & TOUCHE LLP
PO BOX 844708	DALLAS	TX	752844708	AUDIT SERVIES	$670,058
COOLEY LLP
101 CALIFORNIA ST FL 5	SAN FRANCISCO	CA	941115800	LEGAL SERVIES	$614,889

Field	Value	IRS element (for citing)
Cntrct Rcvd Greater Than100 K	12	CntrctRcvdGreaterThan100KCnt
Government Grants	$226,008,550	GovernmentGrantsAmt
All Other Contributions	$91,953,285	AllOtherContributionsAmt
Noncash Contributions	$1,406,589	NoncashContributionsAmt
Total Contributions	$317,961,835	TotalContributionsAmt

Program Service Revenue ProgramServiceRevenueGrp

Field	Value	IRS element (for citing)
Desc	PATENT OFFICE	Desc
Business	900099	BusinessCd
Total Revenue Column	$1,811,390	TotalRevenueColumnAmt
Related Or Exempt Func Income	$1,811,390	RelatedOrExemptFuncIncomeAmt

Field	Value	IRS element (for citing)
Total Program Service Revenue	$1,811,390	TotalProgramServiceRevenueAmt

Investment Income InvestmentIncomeGrp

Field	Value	IRS element (for citing)
Total Revenue Column	$24,570,890	TotalRevenueColumnAmt
Unrelated Business Revenue	-$123,639	UnrelatedBusinessRevenueAmt
Exclusion	$24,694,529	ExclusionAmt

Royalties Revenue RoyaltiesRevenueGrp

Field	Value	IRS element (for citing)
Total Revenue Column	$334,289,595	TotalRevenueColumnAmt
Exclusion	$334,289,595	ExclusionAmt

Gross Rents GrossRentsGrp

Field	Value	IRS element (for citing)
Real	$1,703,504	RealAmt

Less Rental Expenses LessRentalExpensesGrp

Field	Value	IRS element (for citing)
Real	$1,703,504	RealAmt

Rental Income Or Loss RentalIncomeOrLossGrp

Field	Value	IRS element (for citing)
Real	$0	RealAmt

Net Rental Income Or Loss NetRentalIncomeOrLossGrp

Field	Value	IRS element (for citing)
Total Revenue Column	$0	TotalRevenueColumnAmt

Gross Amount Sales Assets GrossAmountSalesAssetsGrp

Field	Value	IRS element (for citing)
Securities	$670,029,914	SecuritiesAmt
Other	$349,168	OtherAmt

Less Cost Oth Basis Sales Expnss LessCostOthBasisSalesExpnssGrp

Field	Value	IRS element (for citing)
Securities	$658,168,915	SecuritiesAmt
Other	$211,356	OtherAmt

Gain Or Loss GainOrLossGrp

Field	Value	IRS element (for citing)
Securities	$11,860,999	SecuritiesAmt
Other	$137,812	OtherAmt

Net Gain Or Loss Investments NetGainOrLossInvestmentsGrp

Field	Value	IRS element (for citing)
Total Revenue Column	$11,998,811	TotalRevenueColumnAmt
Exclusion	$11,998,811	ExclusionAmt

Other Revenue Misc OtherRevenueMiscGrp (2 entries)

DescDesc	BusinessBusinessCd	Total Revenue ColumnTotalRevenueColumnAmt	Related Or Exempt Func IncomeRelatedOrExemptFuncIncomeAmt
GRADUATE OFFICE	900099	$7,121,283	$7,121,283
INFRASTRUCTURE REIMBUR	900099	$269,164	$269,164

Miscellaneous Revenue MiscellaneousRevenueGrp

Field	Value	IRS element (for citing)
Total Revenue Column	$601,350	TotalRevenueColumnAmt
Related Or Exempt Func Income	$601,350	RelatedOrExemptFuncIncomeAmt

Field	Value	IRS element (for citing)
Other Revenue Total	$7,991,797	OtherRevenueTotalAmt

Total Revenue TotalRevenueGrp

Field	Value	IRS element (for citing)
Total Revenue Column	$698,624,318	TotalRevenueColumnAmt
Related Or Exempt Func Income	$9,803,187	RelatedOrExemptFuncIncomeAmt
Unrelated Business Revenue	-$123,639	UnrelatedBusinessRevenueAmt
Exclusion	$370,982,935	ExclusionAmt

Field	Value	IRS element (for citing)
Info In Schedule O Part IX	Yes (X)	InfoInScheduleOPartIXInd

Grants To Domestic Orgs GrantsToDomesticOrgsGrp

Field	Value	IRS element (for citing)
Total	$78,622,580	TotalAmt
Program Services	$78,622,580	ProgramServicesAmt

Grants To Domestic Individuals GrantsToDomesticIndividualsGrp

Field	Value	IRS element (for citing)
Total	$17,469,028	TotalAmt
Program Services	$17,469,028	ProgramServicesAmt

Foreign Grants ForeignGrantsGrp

Field	Value	IRS element (for citing)
Total	$20,997,755	TotalAmt
Program Services	$20,997,755	ProgramServicesAmt

Comp Current Ofcr Directors CompCurrentOfcrDirectorsGrp

Field	Value	IRS element (for citing)
Total	$4,814,094	TotalAmt
Program Services	$966,243	ProgramServicesAmt
Management And General	$3,781,745	ManagementAndGeneralAmt
Fundraising	$66,106	FundraisingAmt

Other Salaries And Wages OtherSalariesAndWagesGrp

Field	Value	IRS element (for citing)
Total	$159,222,303	TotalAmt
Program Services	$139,711,560	ProgramServicesAmt
Management And General	$14,944,012	ManagementAndGeneralAmt
Fundraising	$4,566,731	FundraisingAmt

Pension Plan Contributions PensionPlanContributionsGrp

Field	Value	IRS element (for citing)
Total	-$4,427,159	TotalAmt
Program Services	-$3,815,456	ProgramServicesAmt
Management And General	-$490,964	ManagementAndGeneralAmt
Fundraising	-$120,739	FundraisingAmt

Other Employee Benefits OtherEmployeeBenefitsGrp

Field	Value	IRS element (for citing)
Total	$30,926,845	TotalAmt
Program Services	$27,208,513	ProgramServicesAmt
Management And General	$2,969,939	ManagementAndGeneralAmt
Fundraising	$748,393	FundraisingAmt

Payroll Taxes PayrollTaxesGrp

Field	Value	IRS element (for citing)
Total	$12,313,027	TotalAmt
Program Services	$10,579,526	ProgramServicesAmt
Management And General	$1,428,088	ManagementAndGeneralAmt
Fundraising	$305,413	FundraisingAmt

Fees For Services Legal FeesForServicesLegalGrp

Field	Value	IRS element (for citing)
Total	$4,252,665	TotalAmt
Program Services	$3,524,240	ProgramServicesAmt
Management And General	$717,600	ManagementAndGeneralAmt
Fundraising	$10,825	FundraisingAmt

Fees For Services Accounting FeesForServicesAccountingGrp

Field	Value	IRS element (for citing)
Total	$594,827	TotalAmt
Program Services	$31,507	ProgramServicesAmt
Management And General	$563,320	ManagementAndGeneralAmt

Fees For Srvc Invst Mgmnt Fees FeesForSrvcInvstMgmntFeesGrp

Field	Value	IRS element (for citing)
Total	$1,716,237	TotalAmt
Program Services	$1,716,237	ProgramServicesAmt

Fees For Services Other FeesForServicesOtherGrp

Field	Value	IRS element (for citing)
Total	$71,526,866	TotalAmt
Program Services	$71,517,926	ProgramServicesAmt
Fundraising	$8,940	FundraisingAmt

Advertising AdvertisingGrp

Field	Value	IRS element (for citing)
Total	$1,922,372	TotalAmt
Program Services	$1,256,739	ProgramServicesAmt
Management And General	$62,437	ManagementAndGeneralAmt
Fundraising	$603,196	FundraisingAmt

Office Expenses OfficeExpensesGrp

Field	Value	IRS element (for citing)
Total	$4,838,907	TotalAmt
Program Services	$4,122,859	ProgramServicesAmt
Management And General	$578,906	ManagementAndGeneralAmt
Fundraising	$137,142	FundraisingAmt

Information Technology InformationTechnologyGrp

Field	Value	IRS element (for citing)
Total	$8,516,546	TotalAmt
Program Services	$4,852,023	ProgramServicesAmt
Management And General	$3,485,279	ManagementAndGeneralAmt
Fundraising	$179,244	FundraisingAmt

Occupancy OccupancyGrp

Field	Value	IRS element (for citing)
Total	$14,817,332	TotalAmt
Program Services	$13,158,928	ProgramServicesAmt
Management And General	$1,631,230	ManagementAndGeneralAmt
Fundraising	$27,174	FundraisingAmt

Travel TravelGrp

Field	Value	IRS element (for citing)
Total	$4,076,191	TotalAmt
Program Services	$3,676,527	ProgramServicesAmt
Management And General	$305,291	ManagementAndGeneralAmt
Fundraising	$94,373	FundraisingAmt

Interest InterestGrp

Field	Value	IRS element (for citing)
Total	$3,817,254	TotalAmt
Program Services	$3,817,254	ProgramServicesAmt

Depreciation Depletion DepreciationDepletionGrp

Field	Value	IRS element (for citing)
Total	$25,697,151	TotalAmt
Program Services	$25,130,397	ProgramServicesAmt
Management And General	$565,603	ManagementAndGeneralAmt
Fundraising	$1,151	FundraisingAmt

Insurance InsuranceGrp

Field	Value	IRS element (for citing)
Total	$2,345,785	TotalAmt
Program Services	$2,311,732	ProgramServicesAmt
Management And General	$34,053	ManagementAndGeneralAmt

Other Expenses OtherExpensesGrp (3 entries)

DescDesc	TotalTotalAmt	Program ServicesProgramServicesAmt	Management And GeneralManagementAndGeneralAmt	FundraisingFundraisingAmt
LAB SUPPLIES	$47,869,678	$47,869,678
UTILITIES	$13,496,441	$13,149,298	$141,783	$205,360
CONTRACTED SVCS - OTHER	$12,027,256	$6,581,224	$4,738,346	$707,686

Total Functional Expenses TotalFunctionalExpensesGrp

Field	Value	IRS element (for citing)
Total	$537,453,981	TotalAmt
Program Services	$494,456,318	ProgramServicesAmt
Management And General	$35,456,668	ManagementAndGeneralAmt
Fundraising	$7,540,995	FundraisingAmt

Savings And Temp Cash Invst SavingsAndTempCashInvstGrp

Field	Value	IRS element (for citing)
BOY	$292,352,690	BOYAmt
EOY	$313,736,119	EOYAmt

Pledges And Grants Receivable PledgesAndGrantsReceivableGrp

Field	Value	IRS element (for citing)
BOY	$78,577,549	BOYAmt
EOY	$45,828,948	EOYAmt

Oth Notes Loans Receivable Net OthNotesLoansReceivableNetGrp

Field	Value	IRS element (for citing)
BOY	$4,600,071	BOYAmt
EOY	$5,575,183	EOYAmt

Prepaid Expenses Defrd Charges PrepaidExpensesDefrdChargesGrp

Field	Value	IRS element (for citing)
BOY	$14,722,526	BOYAmt
EOY	$9,228,731	EOYAmt

Field	Value	IRS element (for citing)
Land Bldg Equip Cost Or Other Bss	$687,393,360	LandBldgEquipCostOrOtherBssAmt
Land Bldg Equip Accum Deprec	$414,638,517	LandBldgEquipAccumDeprecAmt

Land Bldg Equip Basis Net LandBldgEquipBasisNetGrp

Field	Value	IRS element (for citing)
BOY	$267,793,844	BOYAmt
EOY	$272,754,843	EOYAmt

Investments Pub Traded Sec InvestmentsPubTradedSecGrp

Field	Value	IRS element (for citing)
BOY	$195,713,207	BOYAmt
EOY	$261,888,242	EOYAmt

Investments Other Securities InvestmentsOtherSecuritiesGrp

Field	Value	IRS element (for citing)
BOY	$382,910,823	BOYAmt
EOY	$498,897,776	EOYAmt

Other Assets Total OtherAssetsTotalGrp

Field	Value	IRS element (for citing)
BOY	$63,247,086	BOYAmt
EOY	$52,707,056	EOYAmt

Total Assets TotalAssetsGrp

Field	Value	IRS element (for citing)
BOY	$1,299,917,796	BOYAmt
EOY	$1,460,616,898	EOYAmt

Accounts Payable Accr Expnss AccountsPayableAccrExpnssGrp

Field	Value	IRS element (for citing)
BOY	$88,893,853	BOYAmt
EOY	$66,753,131	EOYAmt

Deferred Revenue DeferredRevenueGrp

Field	Value	IRS element (for citing)
BOY	$121,509,072	BOYAmt
EOY	$91,126,141	EOYAmt

Tax Exempt Bond Liabilities TaxExemptBondLiabilitiesGrp

Field	Value	IRS element (for citing)
BOY	$16,755,932	BOYAmt
EOY	$13,849,275	EOYAmt

Mortg Notes Pybl Scrd Invst Prop MortgNotesPyblScrdInvstPropGrp

Field	Value	IRS element (for citing)
BOY	$102,687,206	BOYAmt
EOY	$99,993,032	EOYAmt

Other Liabilities OtherLiabilitiesGrp

Field	Value	IRS element (for citing)
BOY	$38,282,518	BOYAmt
EOY	$35,043,765	EOYAmt

Total Liabilities TotalLiabilitiesGrp

Field	Value	IRS element (for citing)
BOY	$368,128,581	BOYAmt
EOY	$306,765,344	EOYAmt

Field	Value	IRS element (for citing)
Organization Follows FASB117	Yes (X)	OrganizationFollowsFASB117Ind

No Donor Restriction Net Assets NoDonorRestrictionNetAssetsGrp

Field	Value	IRS element (for citing)
BOY	$691,565,880	BOYAmt
EOY	$874,481,554	EOYAmt

Donor Restriction Net Assets DonorRestrictionNetAssetsGrp

Field	Value	IRS element (for citing)
BOY	$240,223,335	BOYAmt
EOY	$279,370,000	EOYAmt

Total Net Assets Fund Balance TotalNetAssetsFundBalanceGrp

Field	Value	IRS element (for citing)
BOY	$931,789,215	BOYAmt
EOY	$1,153,851,554	EOYAmt

Tot Liab Net Assets Fund Balance TotLiabNetAssetsFundBalanceGrp

Field	Value	IRS element (for citing)
BOY	$1,299,917,796	BOYAmt
EOY	$1,460,616,898	EOYAmt

Field	Value	IRS element (for citing)
Reconcilation Revenue Expnss	$161,170,337	ReconcilationRevenueExpnssAmt
Net Unrlzd Gains Losses Invst	$60,892,002	NetUnrlzdGainsLossesInvstAmt
Other Changes In Net Assets	$0	OtherChangesInNetAssetsAmt
Method Of Accounting Accrual	Yes (X)	MethodOfAccountingAccrualInd
Accountant Compile Or Review	0	AccountantCompileOrReviewInd
FS Audited	Yes (1)	FSAuditedInd

FS Audited Basis FSAuditedBasisGrp

Field	Value	IRS element (for citing)
Consolidated Basis Fincl Stmt	Yes (X)	ConsolidatedBasisFinclStmtInd

Field	Value	IRS element (for citing)
Audit Committee	Yes (1)	AuditCommitteeInd
Federal Grant Audit Required	Yes (1)	FederalGrantAuditRequiredInd
Federal Grant Audit Performed	Yes (1)	FederalGrantAuditPerformedInd

Schedule A IRS990ScheduleA

Field	Value	IRS element (for citing)
Public Organization170	Yes (X)	PublicOrganization170Ind

Gifts Grants Contri Rcvd170 GiftsGrantsContriRcvd170Grp

Field	Value	IRS element (for citing)
Current Tax Year Minus4 Years	$418,691,076	CurrentTaxYearMinus4YearsAmt
Current Tax Year Minus3 Years	$372,859,914	CurrentTaxYearMinus3YearsAmt
Current Tax Year Minus2 Years	$395,238,681	CurrentTaxYearMinus2YearsAmt
Current Tax Year Minus1 Year	$370,268,955	CurrentTaxYearMinus1YearAmt
Current Tax Year	$317,961,835	CurrentTaxYearAmt
Total	$1,875,020,461	TotalAmt

Total Calendar Year170 TotalCalendarYear170Grp

Field	Value	IRS element (for citing)
Current Tax Year Minus4 Years	$418,691,076	CurrentTaxYearMinus4YearsAmt
Current Tax Year Minus3 Years	$372,859,914	CurrentTaxYearMinus3YearsAmt
Current Tax Year Minus2 Years	$395,238,681	CurrentTaxYearMinus2YearsAmt
Current Tax Year Minus1 Year	$370,268,955	CurrentTaxYearMinus1YearAmt
Current Tax Year	$317,961,835	CurrentTaxYearAmt
Total	$1,875,020,461	TotalAmt

Field	Value	IRS element (for citing)
Substantial Contributors Tot	$191,520,719	SubstantialContributorsTotAmt
Public Support Total170	$1,683,499,742	PublicSupportTotal170Amt

Gross Investment Income170 GrossInvestmentIncome170Grp

Field	Value	IRS element (for citing)
Current Tax Year Minus4 Years	$77,075,770	CurrentTaxYearMinus4YearsAmt
Current Tax Year Minus3 Years	$145,028,308	CurrentTaxYearMinus3YearsAmt
Current Tax Year Minus2 Years	$394,336,218	CurrentTaxYearMinus2YearsAmt
Current Tax Year Minus1 Year	$250,023,990	CurrentTaxYearMinus1YearAmt
Current Tax Year	$360,563,989	CurrentTaxYearAmt
Total	$1,227,028,275	TotalAmt

Other Income170 OtherIncome170Grp

Field	Value	IRS element (for citing)
Current Tax Year Minus4 Years	$3,005,052	CurrentTaxYearMinus4YearsAmt
Current Tax Year Minus3 Years	$24,140,190	CurrentTaxYearMinus3YearsAmt
Current Tax Year Minus2 Years	$7,100,379	CurrentTaxYearMinus2YearsAmt
Current Tax Year Minus1 Year	$9,151,811	CurrentTaxYearMinus1YearAmt
Total	$43,397,432	TotalAmt

Field	Value	IRS element (for citing)
Total Support	$3,145,446,168	TotalSupportAmt
Gross Receipts Rltd Activities	$21,843,091	GrossReceiptsRltdActivitiesAmt
Public Support CY170	0.53520	PublicSupportCY170Pct
Public Support PY170	0.59500	PublicSupportPY170Pct
Thirty Thr Pct Suprt Tests CY170	Yes (X)	ThirtyThrPctSuprtTestsCY170Ind

Form990 Schedule A Part VI Form990ScheduleAPartVIGrp

Field	Value	IRS element (for citing)
Form And Line Reference	SCHEDULE A, PART II, LINE 10, EXPLANATION OF OTHER INCOME:	FormAndLineReferenceDesc
Explanation	OTHER INCOME - 2020 AMOUNT: $ 3,005,052. 2021 AMOUNT: $ 24,140,190. 2022 AMOUNT: $ 7,100,379. 2023 AMOUNT: $ 9,151,811. 2024 AMOUNT: $ 0.	ExplanationTxt

Schedule B IRS990ScheduleB

Contributor Information ContributorInformationGrp

Field	Value	IRS element (for citing)
Contributor	RESTRICTED	ContributorNum

Contributor Business Name ContributorBusinessName

Field	Value	IRS element (for citing)
Business Name Line1	RESTRICTED	BusinessNameLine1

Contributor US Address ContributorUSAddress

Field	Value	IRS element (for citing)
Address Line1	RESTRICTED	AddressLine1
Address Line2	RESTRICTED	AddressLine2
City	RESTRICTED	City
State	RESTRICTED	State
ZIP Code	RESTRICTED	ZIPCode

Field	Value	IRS element (for citing)
Total Contributions	RESTRICTED	TotalContributionsAmt

Schedule D IRS990ScheduleD

CY Endwmt Fund CYEndwmtFundGrp

Field	Value	IRS element (for citing)
Beginning Year Balance	$243,450,372	BeginningYearBalanceAmt
Contributions	$21,026,673	ContributionsAmt
Investment Earnings Or Losses	$41,013,106	InvestmentEarningsOrLossesAmt
Other Expenditures	$8,574,096	OtherExpendituresAmt
End Year Balance	$296,916,055	EndYearBalanceAmt

CY Minus1 Yr Endwmt Fund CYMinus1YrEndwmtFundGrp

Field	Value	IRS element (for citing)
Beginning Year Balance	$221,387,634	BeginningYearBalanceAmt
Contributions	$1,191,872	ContributionsAmt
Investment Earnings Or Losses	$25,356,505	InvestmentEarningsOrLossesAmt
Other Expenditures	$4,485,639	OtherExpendituresAmt
End Year Balance	$243,450,372	EndYearBalanceAmt

CY Minus2 Yr Endwmt Fund CYMinus2YrEndwmtFundGrp

Field	Value	IRS element (for citing)
Beginning Year Balance	$204,676,160	BeginningYearBalanceAmt
Contributions	$8,112,296	ContributionsAmt
Investment Earnings Or Losses	$12,978,632	InvestmentEarningsOrLossesAmt
Other Expenditures	$4,379,454	OtherExpendituresAmt
End Year Balance	$221,387,634	EndYearBalanceAmt

CY Minus3 Yr Endwmt Fund CYMinus3YrEndwmtFundGrp

Field	Value	IRS element (for citing)
Beginning Year Balance	$237,833,719	BeginningYearBalanceAmt
Contributions	$13,591,076	ContributionsAmt
Investment Earnings Or Losses	-$37,099,889	InvestmentEarningsOrLossesAmt
Other Expenditures	$9,648,746	OtherExpendituresAmt
End Year Balance	$204,676,160	EndYearBalanceAmt

CY Minus4 Yr Endwmt Fund CYMinus4YrEndwmtFundGrp

Field	Value	IRS element (for citing)
Beginning Year Balance	$198,444,686	BeginningYearBalanceAmt
Contributions	$22,060,000	ContributionsAmt
Investment Earnings Or Losses	$23,746,007	InvestmentEarningsOrLossesAmt
Other Expenditures	$6,416,974	OtherExpendituresAmt
End Year Balance	$237,833,719	EndYearBalanceAmt

Field	Value	IRS element (for citing)
Board Designated Balance EOY	0.12000	BoardDesignatedBalanceEOYPct
Prmnnt Endowment Balance EOY	0.36000	PrmnntEndowmentBalanceEOYPct
Term Endowment Balance EOY	0.52000	TermEndowmentBalanceEOYPct
Endowments Held Unrelated Org	0	EndowmentsHeldUnrelatedOrgInd
Endowments Held Related Org	0	EndowmentsHeldRelatedOrgInd

Land LandGrp

Field	Value	IRS element (for citing)
Other Cost Or Other Basis	$19,645,590	OtherCostOrOtherBasisAmt
Book Value	$19,645,590	BookValueAmt

Buildings BuildingsGrp

Field	Value	IRS element (for citing)
Other Cost Or Other Basis	$394,465,893	OtherCostOrOtherBasisAmt
Depreciation	$211,894,125	DepreciationAmt
Book Value	$182,571,768	BookValueAmt

Leasehold Improvements LeaseholdImprovementsGrp

Field	Value	IRS element (for citing)
Other Cost Or Other Basis	$7,073,525	OtherCostOrOtherBasisAmt
Depreciation	$6,281,763	DepreciationAmt
Book Value	$791,762	BookValueAmt

Equipment EquipmentGrp

Field	Value	IRS element (for citing)
Other Cost Or Other Basis	$257,385,335	OtherCostOrOtherBasisAmt
Depreciation	$192,104,652	DepreciationAmt
Book Value	$65,280,683	BookValueAmt

Other Land Buildings OtherLandBuildingsGrp

Field	Value	IRS element (for citing)
Other Cost Or Other Basis	$8,823,017	OtherCostOrOtherBasisAmt
Depreciation	$4,357,977	DepreciationAmt
Book Value	$4,465,040	BookValueAmt

Field	Value	IRS element (for citing)
Total Book Value Land Buildings	$272,754,843	TotalBookValueLandBuildingsAmt

Other Securities OtherSecuritiesGrp

Field	Value	IRS element (for citing)
Desc	INVESTMENT IN LIMITED PARTNERSHIPS	Desc
Book Value	$498,897,776	BookValueAmt
Method Valuation	F	MethodValuationCd

Field	Value	IRS element (for citing)
Total Book Value Securities	$498,897,776	TotalBookValueSecuritiesAmt

Other Liabilities Org OtherLiabilitiesOrgGrp (3 entries)

DescDesc	AmtAmt
PENSION LIABILITY	$444,859
LEASE LIABILITY	$34,438,644
UNITRUST	$160,262

Field	Value	IRS element (for citing)
Total Liability	$35,043,765	TotalLiabilityAmt

Supplemental Information Detail SupplementalInformationDetail

Field	Value	IRS element (for citing)
Form And Line Reference	PART V, LINE 4:	FormAndLineReferenceDesc
Explanation	INVESTMENT RETURN FROM THE ENDOWMENTS SUPPORTS SCIENTIFIC PROJECTS CONSISTENT WITH THE MISSION AND PRINCIPLES OF THE SCRIPPS RESEARCH INSTITUTE.	ExplanationTxt

Schedule F IRS990ScheduleF

Field	Value	IRS element (for citing)
Grant Records Maintained	Yes (1)	GrantRecordsMaintainedInd

Account Activities Outside US AccountActivitiesOutsideUSGrp (7 entries)

RegionRegionTxt	Type Of Activities ConductedTypeOfActivitiesConductedTxt	Specific Services ProvidedSpecificServicesProvidedTxt	Region Total ExpendituresRegionTotalExpendituresAmt
EAST ASIA AND THE PACIFIC	PROGRAM SERVICES	GRANTS FOR SCIENTIFIC RESEARCH	$11,853,731
EUROPE (INCLUDING ICELAND & GREENLAND)	PROGRAM SERVICES	GRANTS FOR SCIENTIFIC RESEARCH	$4,044,844
MIDDLE EAST AND NORTH AFRICA	PROGRAM SERVICES	GRANTS FOR SCIENTIFIC RESEARCH	$240,695
NORTH AMERICA	PROGRAM SERVICES	GRANTS FOR SCIENTIFIC RESEARCH	$3,428,070
SOUTH ASIA	PROGRAM SERVICES	GRANTS FOR SCIENTIFIC RESEARCH	$854,497
SUB-SAHARAN AFRICA	PROGRAM SERVICES	GRANTS FOR SCIENTIFIC RESEARCH	$575,918
CENTRAL AMERICA AND THE CARIBBEAN	INVESTMENTS		$115,419,064

Field	Value	IRS element (for citing)
Subtotal Offices	0	SubtotalOfficesCnt
Subtotal Employees	0	SubtotalEmployeesCnt
Continuation Total Office	0	ContinuationTotalOfficeCnt
Continuation Total Employee	0	ContinuationTotalEmployeeCnt
Total Office	0	TotalOfficeCnt
Total Employee	0	TotalEmployeeCnt
Subtotal Spent	$136,416,819	SubtotalSpentAmt
Continuation Spent	$0	ContinuationSpentAmt
Total Spent	$136,416,819	TotalSpentAmt

Grants To Org Outside US GrantsToOrgOutsideUSGrp (46 entries)

RegionRegionTxt	Purpose Of GrantPurposeOfGrantTxt	Cash GrantCashGrantAmt	Manner Of Cash DisbursementMannerOfCashDisbursementTxt	Non Cash AssistanceNonCashAssistanceAmt
EAST ASIA AND THE PACIFIC	GRANTS FOR SCIENTIFIC RESEARCH	$15,551	ELECTRONIC FUND/WIRE TRANSFER	$0
EAST ASIA AND THE PACIFIC	GRANTS FOR SCIENTIFIC RESEARCH	$1,162,498	ELECTRONIC FUND/WIRE TRANSFER	$0
EAST ASIA AND THE PACIFIC	GRANTS FOR SCIENTIFIC RESEARCH	$62,700	ELECTRONIC FUND/WIRE TRANSFER	$0
EAST ASIA AND THE PACIFIC	GRANTS FOR SCIENTIFIC RESEARCH	$54,444	ELECTRONIC FUND/WIRE TRANSFER	$0
EAST ASIA AND THE PACIFIC	GRANTS FOR SCIENTIFIC RESEARCH	$1,396,601	ELECTRONIC FUND/WIRE TRANSFER	$0
EAST ASIA AND THE PACIFIC	GRANTS FOR SCIENTIFIC RESEARCH	$400,354	ELECTRONIC FUND/WIRE TRANSFER	$0
EAST ASIA AND THE PACIFIC	GRANTS FOR SCIENTIFIC RESEARCH	$184,530	ELECTRONIC FUND/WIRE TRANSFER	$0
EAST ASIA AND THE PACIFIC	GRANTS FOR SCIENTIFIC RESEARCH	$7,826,389	ELECTRONIC FUND/WIRE TRANSFER	$0
EAST ASIA AND THE PACIFIC	GRANTS FOR SCIENTIFIC RESEARCH	$749,664	ELECTRONIC FUND/WIRE TRANSFER	$0
EUROPE (INCLUDING ICELAND & GREENLAND)	GRANTS FOR SCIENTIFIC RESEARCH	$237,809	ELECTRONIC FUND/WIRE TRANSFER	$0
EUROPE (INCLUDING ICELAND & GREENLAND)	GRANTS FOR SCIENTIFIC RESEARCH	$133,510	ELECTRONIC FUND/WIRE TRANSFER	$0
EUROPE (INCLUDING ICELAND & GREENLAND)	GRANTS FOR SCIENTIFIC RESEARCH	$65,116	ELECTRONIC FUND/WIRE TRANSFER	$0
EUROPE (INCLUDING ICELAND & GREENLAND)	GRANTS FOR SCIENTIFIC RESEARCH	$165,243	ELECTRONIC FUND/WIRE TRANSFER	$0
EUROPE (INCLUDING ICELAND & GREENLAND)	GRANTS FOR SCIENTIFIC RESEARCH	$721,529	ELECTRONIC FUND/WIRE TRANSFER	$0
EUROPE (INCLUDING ICELAND & GREENLAND)	GRANTS FOR SCIENTIFIC RESEARCH	$45,136	ELECTRONIC FUND/WIRE TRANSFER	$0
EUROPE (INCLUDING ICELAND & GREENLAND)	GRANTS FOR SCIENTIFIC RESEARCH	$225,323	ELECTRONIC FUND/WIRE TRANSFER	$0
EUROPE (INCLUDING ICELAND & GREENLAND)	GRANTS FOR SCIENTIFIC RESEARCH	$177,553	ELECTRONIC FUND/WIRE TRANSFER	$0
EUROPE (INCLUDING ICELAND & GREENLAND)	GRANTS FOR SCIENTIFIC RESEARCH	$73,312	ELECTRONIC FUND/WIRE TRANSFER	$0
EUROPE (INCLUDING ICELAND & GREENLAND)	GRANTS FOR SCIENTIFIC RESEARCH	$351,259	ELECTRONIC FUND/WIRE TRANSFER	$0
EUROPE (INCLUDING ICELAND & GREENLAND)	GRANTS FOR SCIENTIFIC RESEARCH	$41,734	ELECTRONIC FUND/WIRE TRANSFER	$0
EUROPE (INCLUDING ICELAND & GREENLAND)	GRANTS FOR SCIENTIFIC RESEARCH	$48,159	CHECK	$0
EUROPE (INCLUDING ICELAND & GREENLAND)	GRANTS FOR SCIENTIFIC RESEARCH	$1,262,960	ELECTRONIC FUND/WIRE TRANSFER	$0
EUROPE (INCLUDING ICELAND & GREENLAND)	GRANTS FOR SCIENTIFIC RESEARCH	$35,167	ELECTRONIC FUND/WIRE TRANSFER	$0
EUROPE (INCLUDING ICELAND & GREENLAND)	GRANTS FOR SCIENTIFIC RESEARCH	$45,890	ELECTRONIC FUND/WIRE TRANSFER	$0
EUROPE (INCLUDING ICELAND & GREENLAND)	GRANTS FOR SCIENTIFIC RESEARCH	$16,403	ELECTRONIC FUND/WIRE TRANSFER	$0
EUROPE (INCLUDING ICELAND & GREENLAND)	GRANTS FOR SCIENTIFIC RESEARCH	$52,314	ELECTRONIC FUND/WIRE TRANSFER	$0
EUROPE (INCLUDING ICELAND & GREENLAND)	GRANTS FOR SCIENTIFIC RESEARCH	$13,190	ELECTRONIC FUND/WIRE TRANSFER	$0
EUROPE (INCLUDING ICELAND & GREENLAND)	GRANTS FOR SCIENTIFIC RESEARCH	$115,904	ELECTRONIC FUND/WIRE TRANSFER	$0
EUROPE (INCLUDING ICELAND & GREENLAND)	GRANTS FOR SCIENTIFIC RESEARCH	$217,333	ELECTRONIC FUND/WIRE TRANSFER	$0
MIDDLE EAST AND NORTH AFRICA	GRANTS FOR SCIENTIFIC RESEARCH	$240,695	ELECTRONIC FUND/WIRE TRANSFER	$0
NORTH AMERICA	GRANTS FOR SCIENTIFIC RESEARCH	$192,384	ELECTRONIC FUND/WIRE TRANSFER	$0
NORTH AMERICA	GRANTS FOR SCIENTIFIC RESEARCH	$187,917	ELECTRONIC FUND/WIRE TRANSFER	$0
NORTH AMERICA	GRANTS FOR SCIENTIFIC RESEARCH	$2,503,500	ELECTRONIC FUND/WIRE TRANSFER	$0
NORTH AMERICA	GRANTS FOR SCIENTIFIC RESEARCH	$544,269	ELECTRONIC FUND/WIRE TRANSFER	$0
SOUTH ASIA	GRANTS FOR SCIENTIFIC RESEARCH	$192,541	ELECTRONIC FUND/WIRE TRANSFER	$0
SOUTH ASIA	GRANTS FOR SCIENTIFIC RESEARCH	$68,105	ELECTRONIC FUND/WIRE TRANSFER	$0
SOUTH ASIA	GRANTS FOR SCIENTIFIC RESEARCH	$8,985	ELECTRONIC FUND/WIRE TRANSFER	$0
SOUTH ASIA	GRANTS FOR SCIENTIFIC RESEARCH	$257,496	ELECTRONIC FUND/WIRE TRANSFER	$0
SOUTH ASIA	GRANTS FOR SCIENTIFIC RESEARCH	$223,620	ELECTRONIC FUND/WIRE TRANSFER	$0
SOUTH ASIA	GRANTS FOR SCIENTIFIC RESEARCH	$100,127	ELECTRONIC FUND/WIRE TRANSFER	$0
SUB-SAHARAN AFRICA	GRANTS FOR SCIENTIFIC RESEARCH	$53,946	ELECTRONIC FUND/WIRE TRANSFER	$0
SUB-SAHARAN AFRICA	GRANTS FOR SCIENTIFIC RESEARCH	$175,328	ELECTRONIC FUND/WIRE TRANSFER	$0
SUB-SAHARAN AFRICA	GRANTS FOR SCIENTIFIC RESEARCH	$52,606	ELECTRONIC FUND/WIRE TRANSFER	$0
SUB-SAHARAN AFRICA	GRANTS FOR SCIENTIFIC RESEARCH	$108,000	ELECTRONIC FUND/WIRE TRANSFER	$0
SUB-SAHARAN AFRICA	GRANTS FOR SCIENTIFIC RESEARCH	$148,238	ELECTRONIC FUND/WIRE TRANSFER	$0
SUB-SAHARAN AFRICA	GRANTS FOR SCIENTIFIC RESEARCH	$37,800	ELECTRONIC FUND/WIRE TRANSFER	$0

Field	Value	IRS element (for citing)
Total501c3 Org	46	Total501c3OrgCnt
Total Other Org	0	TotalOtherOrgCnt
Transfer To Foreign Corp	Yes (1)	TransferToForeignCorpInd
Interest In Foreign Trust	0	InterestInForeignTrustInd
Foreign Corp Ownership	Yes (1)	ForeignCorpOwnershipInd
Passive Foreign Investmest Co	Yes (1)	PassiveForeignInvestmestCoInd
Foreign Partnership	Yes (1)	ForeignPartnershipInd
Boycott Countries	0	BoycottCountriesInd

Supplemental Information Detail SupplementalInformationDetail (2 entries)

Form And Line ReferenceFormAndLineReferenceDesc	ExplanationExplanationTxt
PART I, LINE 2:	TSRI MONITORS THE AMOUNTS PROVIDED TO THE FOREIGN ORGANIZATION BY ADHERENCE TO A GRANT CONTRACT AND MONITORS DETAILED BILLING STATEMENTS OF RESEARCH EXPENDITURES.
SCHEDULE F, PART IV:	TSRI HAS LESS THAN 10% OWNERSHIP IN A FOREIGN CORPORATION DURING THE TAX YEAR, AND THEREFORE, WAS NOT REQUIRED TO FILE FORM 5471.

Schedule I IRS990ScheduleI

Field	Value	IRS element (for citing)
Grant Records Maintained	Yes (1)	GrantRecordsMaintainedInd

Recipient Table RecipientTable (141 entries)

Address Line1USAddress/AddressLine1Txt	CityUSAddress/CityNm	State AbbreviationUSAddress/StateAbbreviationCd	ZIPUSAddress/ZIPCd	Recipient EINRecipientEIN	Cash GrantCashGrantAmt	Non Cash AssistanceNonCashAssistanceAmt	Purpose Of GrantPurposeOfGrantTxt	IRC SectionIRCSectionDesc	Address Line2USAddress/AddressLine2Txt
1NHEALTH INC
424 E CENTRAL BLVD	ORLANDO	FL	32801	832789875	$204,423	$0	GRANTS FOR SCIENTIFIC RESEARCH
ABZENA (SAN DIEGO) INC
8810 REHCO RD	SAN DIEGO	CA	92121	731731905	$125,176	$0	GRANTS FOR SCIENTIFIC RESEARCH
AIT WORLDWIDE LOGISTICS INC
1820 W 19TH ST	TORRANCE	CA	90501	363033973	$19,575	$0	GRANTS FOR SCIENTIFIC RESEARCH	501(C)(3)
ALBERT EINSTEIN COLLEGE OF MEDICINE
1300 MORRIS PARK AVE	BRONX	NY	10461	830621846	$135,720	$0	GRANTS FOR SCIENTIFIC RESEARCH	501(C)(3)
APPLIED BIOMEDICAL SCIENCE INSTITUTE
11011 VIA FRONTERA STE D	SAN DIEGO	CA	92127	825056708	$445,162	$0	GRANTS FOR SCIENTIFIC RESEARCH	501(C)(3)
AUGUSTA UNIVERSITY RESEARCH INSTITUTE INC
PO BOX 945552	ATLANTA	GA	30394	581418202	$728,286	$0	GRANTS FOR SCIENTIFIC RESEARCH	501(C)(3)
AVANCE BIOSCIENCES INC
9770 WEST LITTLE YORK RD	HOUSTON	TX	77040	275231828	$91,883	$0	GRANTS FOR SCIENTIFIC RESEARCH
BAYLOR COLLEGE OF MEDICINE
ONE BAYLOR PLAZA MS BCM160	HOUSTON	TX	77030	741613878	$213,308	$0	GRANTS FOR SCIENTIFIC RESEARCH	501(C)(3)
BBG ADVANCED THERAPIES
6211 IH 10 WEST	SAN ANTONIO	TX	78201	422216869	$70,362	$0	GRANTS FOR SCIENTIFIC RESEARCH
BENAROYA RESEARCH INSTITUTE AT VIRGINIA MASON
1201 NINTH AVE	SEATTLE	WA	98101	910653422	$19,289	$0	GRANTS FOR SCIENTIFIC RESEARCH	501(C)(3)
BERKSHIRE STERILE MANUFACTURING INC
480 PLEASANT ST	LEE	MA	01238	471007988	$42,461	$0	GRANTS FOR SCIENTIFIC RESEARCH
BETH ISRAEL DEACONESS MEDICAL CTR INC
330 BROOKLINE AVE	BOSTON	MA	02215	042103881	$84,651	$0	GRANTS FOR SCIENTIFIC RESEARCH	501(C)(3)
BIODURO LLC
11011 TORREYANA RD	SAN DIEGO	CA	92121	203271146	$260,122	$0	GRANTS FOR SCIENTIFIC RESEARCH
BLOOD ASSURANCE INC
705 E 3RD STREET	CHATTANOOGA	TN	37403	620842419	$79,845	$0	GRANTS FOR SCIENTIFIC RESEARCH	501(C)(3)
BLOODWORKS NORTHWEST
921 TERRY AVE	SEATTLE	WA	98104	911019655	$490,940	$0	GRANTS FOR SCIENTIFIC RESEARCH	501(C)(3)
BOSTON CHILDRENS HOSPITAL
PO BOX 414413	BOSTON	MA	02241	042774441	$73,596	$0	GRANTS FOR SCIENTIFIC RESEARCH	501(C)(3)
BOSTON UNIVERSITY
ONE SILBER WAY	BOSTON	MA	02215	042103547	$235,781	$0	GRANTS FOR SCIENTIFIC RESEARCH	501(C)(3)
BRIGHAM YOUNG UNIVERSITY
A-153 ASB	PROVO	UT	84602	870217280	$134,874	$0	GRANTS FOR SCIENTIFIC RESEARCH	501(C)(3)
BROAD INSTITUTE
415 MAIN ST	CAMBRIDGE	MA	02142	263428781	$1,145,915	$0	GRANTS FOR SCIENTIFIC RESEARCH	501(C)(3)
CARE EVOLUTION
625 N MAIN ST	ANN ARBOR	MI	48104	731677920	$5,935,978	$0	GRANTS FOR SCIENTIFIC RESEARCH
CHARLES RIVER LABORATORIES ASHLAND LLC
251 BALLARDVALE ST	WILMINGTON	MA	01887	562479324	$1,265,010	$0	GRANTS FOR SCIENTIFIC RESEARCH
CHARLES RIVER LABORATORIES INC
FRANKLIN COMMONS 106 RTE 32	N FRANKLIN	CT	06254	760509980	$248,184	$0	GRANTS FOR SCIENTIFIC RESEARCH
CLEARCUT RESEARCH LLC
7007 WINCHESTER CIR STE 130 140	BOULDER	CO	80301	871668978	$43,162	$0	GRANTS FOR SCIENTIFIC RESEARCH
CLINICAL BIOSAFETY SERVICES LLC
16150 MAIN CIRCLE DR STE 100	CHESTERFIELD	MO	63017	815396979	$9,550	$0	GRANTS FOR SCIENTIFIC RESEARCH
CLINIGEN CLINICAL SUPPLIES MANAGEMENT INC
300 TECHNOLOGY DR	MALVERN	PA	19355	814016259	$37,314	$0	GRANTS FOR SCIENTIFIC RESEARCH	501(C)(3)
COLUMBIA UNIVERISTY
622 WEST 113TH STREET MAIL CODE 452	NEW YORK	NY	10025	135598093	$658,961	$0	GRANTS FOR SCIENTIFIC RESEARCH	501(C)(3)
CPC SCIENTIFIC INC
1900 MCCARTHY BLVD STE 2004	MILPITAS	CA	95035	522459250	$6,081	$0	GRANTS FOR SCIENTIFIC RESEARCH	501(C)(3)
CROWN BIOSCIENCE INC
16550 WEST BERNARDO DRIVE BLDG 5	SAN DIEGO	CA	92127	204873924	$33,564	$0	GRANTS FOR SCIENTIFIC RESEARCH		STE 525
CRYOPORT SYSTEMS INC
PO BOX 205955	DALLAS	TX	75063	954835200	$33,655	$0	GRANTS FOR SCIENTIFIC RESEARCH	501(C)(3)
CURIA GLOBAL INC
26 CORPORATE CIR	ALBANY	NY	12203	141742717	$23,836	$0	GRANTS FOR SCIENTIFIC RESEARCH
CYPROTEX US LLC
200 STAPLES DR 1ST FL	FRAMINGHAM	MA	01702	203810071	$56,335	$0	GRANTS FOR SCIENTIFIC RESEARCH
DENVER HEALTH & HOSPITAL AUTHORITY
777 BANNOCK STREET	DENVER	CO	80204	841343242	$382,333	$0	GRANTS FOR SCIENTIFIC RESEARCH	501(C)(3)
EDITCO BIO INC
600 SAGINAW DR	REDWOOD CITY	CA	94063	934532070	$11,357	$0	GRANTS FOR SCIENTIFIC RESEARCH
EMORY UNIVERSITY
1762 CLIFTON RD STE 1400	ATLANTA	GA	30322	580566256	$4,620,970	$0	GRANTS FOR SCIENTIFIC RESEARCH	501(C)(3)
EUROFINS DISCOVERX LLC
47100 BAYSIDE PKWY	FREMONT	CA	94538	943317322	$37,120	$0	GRANTS FOR SCIENTIFIC RESEARCH
EYECRO LLC
5301 N BEVERLY DR	OKLAHOMA CITY	OK	73105	272549520	$200,000	$0	GRANTS FOR SCIENTIFIC RESEARCH	501(C)(3)
FLORIDA STATE UNIVERSITY
874 TRADITIONS WAY PO BOX 3064166	TALLAHASSEE	FL	32306	591961248	$211,227	$0	GRANTS FOR SCIENTIFIC RESEARCH	GOV'T
FRED HUTCHINSON CANCER RESEARCH CENTER
1100 FAIRVIEW AVE N PO BOX 19024	SEATTLE	WA	98109	911935159	$900,437	$0	GRANTS FOR SCIENTIFIC RESEARCH	501(C)(3)
GEORGIA TECH RESEARCH CORPORATION
926 DALNEY ST NW	ATLANTA	GA	30318	580603146	$452,993	$0	GRANTS FOR SCIENTIFIC RESEARCH	501(C)(3)
GSD HEALTH RESEARCH INC
2119 SAND CREST WAY	SAN MARCOS	CA	92078	332834539	$30,000	$0	GRANTS FOR SCIENTIFIC RESEARCH
H LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE INC
12902 MAGNOLIA DR	TAMPA	FL	33612	391415661	$75,560	$0	GRANTS FOR SCIENTIFIC RESEARCH	501(C)(3)
HIV & AGING RESEARCH PROJECT PS
1775 E PALM CANYON DR STE 110-349	PALM SPRINGS	CA	92264	473892886	$149,727	$0	GRANTS FOR SCIENTIFIC RESEARCH	501(C)(3)
HSRL HOLDINGS LLC DBA STAGEBIO
5930 MAIN ST	MOUNT JACKSON	VA	22842	832519693	$22,096	$0	GRANTS FOR SCIENTIFIC RESEARCH
ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI
ONE GUSTAVE L LEVY PLACE BOX 1049	NEW YORK	NY	10029	136171197	$1,231,337	$0	GRANTS FOR SCIENTIFIC RESEARCH	501(C)(3)
INOTIV INC
2701 KENT AVE	W LAFAYETTE	IN	47906	351435024	$65,040	$0	GRANTS FOR SCIENTIFIC RESEARCH
INTERNATIONAL AIDS VACCINE INITIATIVE
125 BROAD STREET 9TH FLOOR	NEW YORK	NY	10004	133870223	$3,727,010	$0	GRANTS FOR SCIENTIFIC RESEARCH	501(C)(3)
IQVIA RDS INC
2400 ELLIS RD	DURHAM	NC	27703	561323952	$1,689,621	$0	GRANTS FOR SCIENTIFIC RESEARCH
J DAVID GLADSTONE INSTITUTE
1650 OWENS STREET	SAN FRANCISCO	CA	94158	237203666	$327,905	$0	GRANTS FOR SCIENTIFIC RESEARCH	501(C)(3)
JOHNS HOPKINS CENTRAL LOCKBOX
12529 COLLECTION CENTER DR	CHICAGO	IL	60693	520595110	$156,388	$0	GRANTS FOR SCIENTIFIC RESEARCH	501(C)(3)
KALO CLINICAL RESEARCH
350 EAST 400 SOUTH STE 237	SALT LAKE CITY	UT	84111	841972967	$133,788	$0	GRANTS FOR SCIENTIFIC RESEARCH	501(C)(3)
KEE GROUP LLC
22 FIORENZA DRIVE	WILMINGTON	MA	01887	933759464	$28,500	$0	GRANTS FOR SCIENTIFIC RESEARCH
LA JOLLA INSTITUTE FOR IMMUNOLOGY
9420 ATHENA CIRCLE	LA JOLLA	CA	92037	330328688	$3,716,736	$0	GRANTS FOR SCIENTIFIC RESEARCH	501(C)(3)
LABCORP CENTRAL LABORATORY SERVICES LP
8211 SCICOR DR	INDIANAPOLIS	IN	46214	351937506	$448,081	$0	GRANTS FOR SCIENTIFIC RESEARCH
LABCORP EARLY DEVELOPMENT LABORATORIES INC
3301 KINSMAN BLVD	MADISON	WI	53704	540898188	$110,962	$0	GRANTS FOR SCIENTIFIC RESEARCH	501(C)(3)
LABNETWORK INC
28288 NETWORK PL	CHICAGO	IL	60673	472338171	$38,250	$0	GRANTS FOR SCIENTIFIC RESEARCH
LIFESHARE BLOOD CENTER
8910 LINWOOD AVE	SHREVEPORT	LA	71106	720611367	$100,370	$0	GRANTS FOR SCIENTIFIC RESEARCH	501(C)(3)
LIFESOUTH COMMUNITY BLOOD CENTERS INC
4039 NEWBERRY RD	GAINESVILLE	FL	32607	591545914	$9,864	$0	GRANTS FOR SCIENTIFIC RESEARCH	501(C)(3)
LOTUS CLINICAL RESEARCH LLC
PO BOX 11407 DEPT 6425	BIRMINGHAM	AL	35246	954839949	$2,581,485	$0	GRANTS FOR SCIENTIFIC RESEARCH
MARY'S CENTER FOR MATERNAL & CHILD CARE
2333 ONTARIO RD NW	WASHINGTON	DC	20009	521594116	$420,348	$0	GRANTS FOR SCIENTIFIC RESEARCH	501(C)(3)
MASSACHUSETTS GENERAL HOSPITAL
PO BOX 3829	BOSTON	MA	02241	042697983	$1,277,865	$0	GRANTS FOR SCIENTIFIC RESEARCH	501(C)(3)
MASSACHUSETTS INSTITUE OF TECHNOLOGY
77 MASSACHUSETTS AVE NE49-31	CAMBRIDGE	MA	02139	042103594	$276,985	$0	GRANTS FOR SCIENTIFIC RESEARCH	501(C)(3)
MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH
200 FIRST ST SW	ROCHESTER	MN	55905	411506440	$82,935	$0	GRANTS FOR SCIENTIFIC RESEARCH	501(C)(3)
MEDIDATA SOLUTIONS INC
350 HUDSON ST 9TH FL	NEW YORK	NY	10014	134066508	$63,533	$0	GRANTS FOR SCIENTIFIC RESEARCH
MELIOR DISCOVERY INC
860 SPRINGDALE DR STE 500	EXTON	PA	19341	202055208	$31,720	$0	GRANTS FOR SCIENTIFIC RESEARCH	501(C)(3)
MONTAGE MARKETING GROUP LLC
5714 ABERDEEN RD	BETHESDA	MD	20814	472971390	$3,221,399	$0	GRANTS FOR SCIENTIFIC RESEARCH
MINARIS REGENERATIVE MEDICINE LLC
75 COMMERCE DRIVE	ALLENDALE	NJ	07401	223560033	$3,307,500	$0	GRANTS FOR SCIENTIFIC RESEARCH
MYDATA-TRUST INC
100 B ST STE 400	SANTA ROSA	CA	95401	301207763	$27,785	$0	GRANTS FOR SCIENTIFIC RESEARCH
NEW YORK BLOOD CENTER INC
310 EAST 67TH ST	NEW YORK	NY	10065	131949477	$291,860	$0	GRANTS FOR SCIENTIFIC RESEARCH	501(C)(3)
NORTHWESTERN UNIVERSITY
633 CLARK ST	EVANSTON	IL	60208	362167817	$115,341	$0	GRANTS FOR SCIENTIFIC RESEARCH	501(C)(3)
OKLAHOMA BLOOD INSTITUTE
DEPT 96-0115	OKLAHOMA CITY	OK	73196	731008735	$474,445	$0	GRANTS FOR SCIENTIFIC RESEARCH	501(C)(3)
OREGON HEALTH & SCIENCE UNIVERSITY
PO BOX 3003	PORTLAND	OR	97208	931176109	$651,081	$0	GRANTS FOR SCIENTIFIC RESEARCH	501(C)(3)
OREGON STATE UNIVERSITY
1500 SW JEFFERSON WAY	CORVALLIS	OR	97339	611730890	$440,031	$0	GRANTS FOR SCIENTIFIC RESEARCH	GOV'T
PHARMARON INC
201 E JEFFERSON ST	LOUISVILLE	KY	40202	208419781	$1,242,270	$0	GRANTS FOR SCIENTIFIC RESEARCH
PHARMALEGACY RESEARCH LLC DBA BIOLEGACY RESEARCH
6042 CORNERSTONE CT W - STE E	SAN DIEGO	CA	92121	992634394	$9,052	$0	GRANTS FOR SCIENTIFIC RESEARCH
PREMIER RESEARCH ACQUISITION CORP
3800 PARAMOUNT PKWY STE 400	MORRISVILLE	NC	27560	814085446	$24,325	$0	GRANTS FOR SCIENTIFIC RESEARCH
PREMIER RESEARCH INTERNATIONAL LLC
3800 PARAMOUNT PKY STE 400	MORRISVILLE	NC	27560	262481486	$9,234,504	$0	GRANTS FOR SCIENTIFIC RESEARCH
PUBLIC HEALTH INSTITUTE
555 12TH STREET 6TH FLOOR	OAKLAND	CA	94607	941646278	$21,125	$0	GRANTS FOR SCIENTIFIC RESEARCH	501(C)(3)
PURACYP INC
5900 SEA LION PL STE 130	CARLSBAD	CA	92008	330974050	$64,569	$0	GRANTS FOR SCIENTIFIC RESEARCH
Q SQUARED SOLUTIONS HOLDINGS LLC
2400 ELLIS RD	DURHAM	NC	27703	474181370	$139,177	$0	GRANTS FOR SCIENTIFIC RESEARCH
QUOTIENT SCIENCES - MIAMI INC
3898 NW 7TH STREET	MIAMI	FL	33126	650576605	$82,790	$0	GRANTS FOR SCIENTIFIC RESEARCH
RADY CHILDREN'S INSTITUTE FOR GENOMIC MEDICINE
3020 CHILDRENS WAY MC5129	SAN DIEGO	CA	92123	953814185	$118,267	$0	GRANTS FOR SCIENTIFIC RESEARCH	501(C)(3)
REGENTS OF THE UNIVERSITY OF CALIFORNIA DBA UCSD
9500 GILMAN DR	LA JOLLA	CA	92037	956006144	$2,976,761	$0	GRANTS FOR SCIENTIFIC RESEARCH	501(C)(3)
REGENTS OF THE UNIVERSITY OF CALIFORNIA SANTA CRUZ
DBA UCSC 1156 HIGH ST	SANTA CRUZ	CA	95064	941539563	$150,150	$0	GRANTS FOR SCIENTIFIC RESEARCH	501(C)(3)
RENSSELAER POLYTECHNIC INSTITUTE
110 8TH ST	TROY	NY	12180	141340095	$492,417	$0	GRANTS FOR SCIENTIFIC RESEARCH	501(C)(3)
RESEARCH TRIANGLE INSTITUTE
3040 E CORNWALLIS RD	RESEARCH TRIANGLE PARK	NC	27709	560686338	$78,009	$0	GRANTS FOR SCIENTIFIC RESEARCH	501(C)(3)
RUSH UNIVERSITY MEDICAL CENTER
1700 W VAN BUREN ST	CHICAGO	IL	60612	362174823	$69,749	$0	GRANTS FOR SCIENTIFIC RESEARCH	501(C)(3)
SAMM SOLUTIONS INC
9990 MESA RIM RD STE 100	SAN DIEGO	CA	92121	208712967	$47,793	$0	GRANTS FOR SCIENTIFIC RESEARCH
SAN DIEGO BLOOD BANK
3636 GATEWAY CENTER AVENUE SUITE 10	SAN DIEGO	CA	92102	951696732	$299,464	$0	GRANTS FOR SCIENTIFIC RESEARCH	501(C)(3)
SAN DIEGO STATE UNIVERSITY RESEARCH FOUNDATION
5200 CAMPANILE DRIVE	SAN DIEGO	CA	92182	956042721	$110,593	$0	GRANTS FOR SCIENTIFIC RESEARCH	501(C)(3)
SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE
10901 N TORREY PINES RD	LA JOLLA	CA	92037	510197108	$572,762	$0	GRANTS FOR SCIENTIFIC RESEARCH	501(C)(3)
SCHEPENS EYE RESEARCH INSTITUTE
399 REVOLUTION DR STE 645	SOMERVILLE	MA	02145	042129889	$29,269	$0	GRANTS FOR SCIENTIFIC RESEARCH	501(C)(3)
SCINTILLON INSTITUTE THE
6868 NANCY RIDGE DR	SAN DIEGO	CA	92121	454323888	$37,118	$0	GRANTS FOR SCIENTIFIC RESEARCH	501(C)(3)
SCRIPPS HEALTH
10140 CAMPUS POINT DR SUITE 200	SAN DIEGO	CA	92121	951684089	$787,632	$0	GRANTS FOR SCIENTIFIC RESEARCH	501(C)(3)
SHANGHAI CHEMPARTNER CO LTD DBA CHEMPARTNER CORP
280 UTAH STE 100	SOUTH SAN FRANCISCO	CA	94080	263524884	$1,198,919	$0	GRANTS FOR SCIENTIFIC RESEARCH
SHARP CLINICAL SERVICES LLC
2400 BAGLYOS CIR	BETHLEHEM	PA	18020	320383032	$259,075	$0	GRANTS FOR SCIENTIFIC RESEARCH
SINGULOMICS CORPORATION
1273 OLD JANAL RANCH RD	CHULA VISTA	CA	91915	814261103	$270,037	$0	GRANTS FOR SCIENTIFIC RESEARCH
SINO BIOLOGICAL US INC
1400 LIBERTY RIDGE DR ST 101	WAYNE	PA	19087	371870406	$5,640	$0	GRANTS FOR SCIENTIFIC RESEARCH
SOUTH TEXAS BLOOD & TISSUE
6211 IH 10 WEST	SAN ANTONIO	TX	78201	237379332	$76,976	$0	GRANTS FOR SCIENTIFIC RESEARCH	501(C)(3)
STANFORD UNIVERSITY
485 BROADWAY MAIL CODE 8838	REDWOOD CITY	CA	94063	941156365	$31,633	$0	GRANTS FOR SCIENTIFIC RESEARCH	501(C)(3)
SUNCOAST BLOOD CENTER
3025 LAKEWOOD RANCH BLVD	BRADENTON	FL	34211	590873275	$163,970	$0	GRANTS FOR SCIENTIFIC RESEARCH	501(C)(3)
SYNCHRONY LABS LLC
3908 PATRIOT DRIVE STE 170	DURHAM	NC	27703	461912061	$314,865	$0	GRANTS FOR SCIENTIFIC RESEARCH
SYNSMART RASAYAN RESEARCH LLC
21 JUNIPER CT	NEWTOWN	PA	18940	932803268	$755,478	$0	GRANTS FOR SCIENTIFIC RESEARCH
TEXAS BIOMEDICAL RESEARCH INSTITUTE
PO BOX 760549	SAN ANTONIO	TX	78245	741109630	$964,494	$0	GRANTS FOR SCIENTIFIC RESEARCH	501(C)(3)
TEXAS TECH UNIVERSITY
3601 4TH STREET	LUBBOCK	TX	79430	756002622	$37,120	$0	GRANTS FOR SCIENTIFIC RESEARCH	GOV'T
THE CLEVELAND CLINIC FOUNDATION
9500 EUCLID AVE	CLEVELAND	OH	44195	340714585	$397,284	$0	GRANTS FOR SCIENTIFIC RESEARCH	501(C)(3)
THE JACKSON LABORATORY
90260 COLLECTION CENTER DR	CHICAGO	IL	60693	010211513	$130,612	$0	GRANTS FOR SCIENTIFIC RESEARCH	501(C)(3)
THE REGENTS OF THE UNIV OF CA IRVINE
CONTRACTS GRANTS ACCOUNTING 120	IRVINE	CA	92697	952226406	$33,155	$0	GRANTS FOR SCIENTIFIC RESEARCH	501(C)(3)	THEORY SUITE 200
THE ROCKEFELLER UNIVERISTY
1230 YORK AVE	NEW YORK	NY	10065	131624158	$590,961	$0	GRANTS FOR SCIENTIFIC RESEARCH	501(C)(3)
THE SALK INSTITUTE FOR BIOLOGICAL STUDIES
10010 N TORREY PINES RD	LA JOLLA	CA	92037	952160097	$1,157,441	$0	GRANTS FOR SCIENTIFIC RESEARCH	501(C)(3)
TRANSLATIONAL GENOMICS RESEARCH INSTITUTE
445 N 5TH ST STE 600	PHOENIX	AZ	85004	753065445	$35,187	$0	GRANTS FOR SCIENTIFIC RESEARCH	501(C)(3)
TULANE UNIVERSITY
6823 ST CHARLES AVENUE	NEW ORLEANS	LA	70118	720423889	$1,825,763	$0	GRANTS FOR SCIENTIFIC RESEARCH	501(C)(3)
UNIVERSITY ENTERPRISES CORPORATION AT CSUSB
5500 UNIVERSITY PARKWAY	SAN BERNARDINO	CA	92407	956067343	$44,609	$0	GRANTS FOR SCIENTIFIC RESEARCH
UNIVERSITY OF ALABAMA AT BIRMINGHAM
PEDIATRICS INFECTIOUS DISEASE CHB	BIRMINGHAM	AL	35233	636005396	$16,215	$0	GRANTS FOR SCIENTIFIC RESEARCH	501(C)(3)	128-B 1600 6TH AVE S
UNIV OF CALIFORNIA - DAVIS
202 COUSTEAU PL STE 185	DAVIS	CA	95618	946036494	$63,086	$0	GRANTS FOR SCIENTIFIC RESEARCH	501(C)(3)
UNIV OF CALIFORNIA - LOS ANGELES
10889 WILSHIRE BOULEVARD STE 700	LOS ANGELES	CA	90095	956006143	$154,632	$0	GRANTS FOR SCIENTIFIC RESEARCH	501(C)(3)
UNIVERSITY OF FLORIDA
CONTRACTS GRANTS PO BOX 24736	NEW YORK	NY	10087	556002052	$1,165,401	$0	GRANTS FOR SCIENTIFIC RESEARCH	501(C)(3)
UNIV OF MARYLAND BALTIMORE
650 W BALTIMORE ST	BALTIMORE	MD	21201	526002033	$384,963	$0	GRANTS FOR SCIENTIFIC RESEARCH	501(C)(3)
UNIV OF PENNSYLVANIA
125 S 31ST STE 2000	PHILADELPHIA	PA	19104	231352685	$2,084,173	$0	GRANTS FOR SCIENTIFIC RESEARCH	501(C)(3)
UNIVERSITY OF ARIZONA
PO BOX 41867	TUCSON	AZ	85717	742652689	$63,495	$0	GRANTS FOR SCIENTIFIC RESEARCH	501(C)(3)
UNIVERSITY OF COLORADO
PO BOX 910220	DENVER	CO	80291	846000555	$405,756	$0	GRANTS FOR SCIENTIFIC RESEARCH	501(C)(3)
UNIVERSITY OF DELAWARE
30 LOVETT AVE	NEWARK	DE	19716	516000297	$225,986	$0	GRANTS FOR SCIENTIFIC RESEARCH	501(C)(3)
UNIVERSITY OF GEORGIA RESEARCH FOUNDATION
324 BUSINESS SRVCS 456 E BROAD ST	ATHENS	GA	30602	581353149	$91,258	$0	GRANTS FOR SCIENTIFIC RESEARCH	501(C)(3)
UNIVERSITY OF LOUISIANA AT LAFAYETTE
PO BOX 42570	LAFAYETTE	LA	70504	726000820	$70,965	$0	GRANTS FOR SCIENTIFIC RESEARCH	GOV'T
UNIVERSITY OF MICHIGAN
515 E JEFFERSON	ANN ARBOR	MI	48109	386006309	$207,321	$0	GRANTS FOR SCIENTIFIC RESEARCH	501(C)(3)
UNIVERSITY OF MINNESOTA
PO BOX 1450	MINNEAPOLIS	MN	55485	416007513	$146,524	$0	GRANTS FOR SCIENTIFIC RESEARCH	GOV'T
UNIVERSITY OF PITTSBURGH
128 NORTH CRAIG STREET	PITTSBURGH	PA	15260	250965591	$52,486	$0	GRANTS FOR SCIENTIFIC RESEARCH	501(C)(3)
UNIVERSITY OF ROCHESTER
910 GENESEE ST STE 200	ROCHESTER	NY	14611	160743209	$146,204	$0	GRANTS FOR SCIENTIFIC RESEARCH	501(C)(3)
UNIVERSITY OF SOUTHERN CALIFORNIA
3551 TROUSDALE PARKWAY STE 160	LOS ANGELES	CA	90089	951642394	$610,128	$0	GRANTS FOR SCIENTIFIC RESEARCH	501(C)(3)
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER
5323 HARRY HINES BLVD	DALLAS	TX	75390	756002868	$201,640	$0	GRANTS FOR SCIENTIFIC RESEARCH	501(C)(3)
UNIVERSITY OF UTAH
201 S PRESIDENTS CIR RM 145	SALT LAKE CITY	UT	84112	876000525	$150,959	$0	GRANTS FOR SCIENTIFIC RESEARCH	501(C)(3)
UNIVERSITY OF VIRGINIA
PO BOX 400195	CHARLOTTESVILLE	VA	22904	546001796	$135,903	$0	GRANTS FOR SCIENTIFIC RESEARCH	501(C)(3)
UVAX BIO LLC
100 BIDDLE AVE STE 202	NEWARK	DE	19702	824509259	$110,935	$0	GRANTS FOR SCIENTIFIC RESEARCH	501(C)(3)
VALA SCIENCES INC
6190 CORNERSTONE CT E STE 101-103	SAN DIEGO	CA	92121	200906350	$58,037	$0	GRANTS FOR SCIENTIFIC RESEARCH	501(C)(3)
VERSITI WISCONSIN INC
29779 NETWORK PL	CHICAGO	IL	60673	390807235	$23,690	$0	GRANTS FOR SCIENTIFIC RESEARCH	501(C)(3)
VETERANS MEDICAL RESEARCH FOUNDATION
3350 LA JOLLA VILLAGE DR 151A	SAN DIEGO	CA	92161	330189397	$272,532	$0	GRANTS FOR SCIENTIFIC RESEARCH	501(C)(3)
WASHINGTON UNIVERSITY IN ST LOUIS
700 ROSEDALE AVE CAMPUS BOX 1034	ST LOUIS	MO	63112	430653611	$732,973	$0	GRANTS FOR SCIENTIFIC RESEARCH	501(C)(3)
WEILL MEDICAL COLLEGE OF CORNELL UNIVERSITY
PO BOX 22371 GRANT CONTRACT	NEW YORK	NY	10087	131623978	$159,389	$0	GRANTS FOR SCIENTIFIC RESEARCH	501(C)(3)	ACCOUNTING MELISSA PARAY
WORLD COURIER INC
1313 FOURTH AVE	NEW HYDE PARK	NY	11040	132682321	$15,521	$0	GRANTS FOR SCIENTIFIC RESEARCH
WUXI ADVANCED THERAPIES INC
4751 LEAGUE ISLAND BLVD	PHILADELPHIA	PA	19112	842773437	$50,570	$0	GRANTS FOR SCIENTIFIC RESEARCH	501(C)(3)
XOLLENT BIOTECH INC
1001 WILLIAM MOORE DR BPC 2ND FL	RALEIGH	NC	27606	823775311	$296,752	$0	GRANTS FOR SCIENTIFIC RESEARCH
YALE UNIVERSITY
PO BOX 2038	NEW HAVEN	CT	06521	060646973	$541,666	$0	GRANTS FOR SCIENTIFIC RESEARCH	501(C)(3)

Field	Value	IRS element (for citing)
Total501c3 Org	96	Total501c3OrgCnt
Total Other Org	45	TotalOtherOrgCnt

Grants Other Asst To Indiv In US GrantsOtherAsstToIndivInUSGrp

Field	Value	IRS element (for citing)
Grant Type	SCHOLARSHIPS & STIPENDS, TSRI GRADUATE SCHOOL	GrantTypeTxt
Recipient	440	RecipientCnt
Cash Grant	$17,469,028	CashGrantAmt

Supplemental Information Detail SupplementalInformationDetail

Field	Value	IRS element (for citing)
Form And Line Reference	PART I, LINE 2:	FormAndLineReferenceDesc
Explanation	TSRI MONITORS THE AMOUNTS PROVIDED TO THE DOMESTIC ORGANIZATION BY ADHERENCE TO A GRANT CONTRACT AND MONITORS DETAILED BILLING STATEMENTS OF RESEARCH EXPENDITURES. GRADUATE STUDENT STIPENDS ARE PROCESSED VIA PERSONNEL ACTION FORMS WHICH ARE APPROVED BY THE GRADUATE OFFICE AND HUMAN RESOURCES PRIOR TO BEING SENT TO THE PAYROLL OFFICE. ONCE APPROVED, GRADUATE STUDENTS ARE SET UP IN TSRI'S PAYROLL SYSTEM AND ARE DISPERSED ON THE 1ST AND 15TH OF EACH MONTH. MONITORING IS DONE VIA THE INTERACTION BETWEEN THE STUDENT AND FACULTY ADVISOR. AS LONG AS THE STUDENT IS PROGRESSING, SHE/HE WOULD CONTINUE TO BE PAID.	ExplanationTxt

Schedule J IRS990ScheduleJ

Field	Value	IRS element (for citing)
First Class Or Charter Travel	Yes (X)	FirstClassOrCharterTravelInd
Travel For Companions	Yes (X)	TravelForCompanionsInd
Idemnification Gross Up Pmts	Yes (X)	IdemnificationGrossUpPmtsInd
Housing Allowance Or Residence	Yes (X)	HousingAllowanceOrResidenceInd
Written Policy Ref T And E Expnss	Yes (1)	WrittenPolicyRefTAndEExpnssInd
Substantiation Required	Yes (1)	SubstantiationRequiredInd
Independent Consultant	Yes (X)	IndependentConsultantInd
Form990 Of Other Organizations	Yes (X)	Form990OfOtherOrganizationsInd
Compensation Survey	Yes (X)	CompensationSurveyInd
Board Or Committee Approval	Yes (X)	BoardOrCommitteeApprovalInd
Severance Payment	0	SeverancePaymentInd
Supplemental Nonqual Rtr Plan	0	SupplementalNonqualRtrPlanInd
Equity Based Comp Arrngm	0	EquityBasedCompArrngmInd
Comp Based On Revenue Of Flng Org	0	CompBasedOnRevenueOfFlngOrgInd
Comp Bsd On Rev Related Orgs	0	CompBsdOnRevRelatedOrgsInd
Comp Bsd Net Earns Flng Org	0	CompBsdNetEarnsFlngOrgInd
Comp Bsd Net Earns Rltd Orgs	0	CompBsdNetEarnsRltdOrgsInd
Any Non Fixed Payments	0	AnyNonFixedPaymentsInd
Initial Contract Exception	0	InitialContractExceptionInd

Rltd Org Officer Trst Key Empl RltdOrgOfficerTrstKeyEmplGrp (13 entries)

TitleTitleTxt	Base Compensation Filing OrgBaseCompensationFilingOrgAmt	Compensation Based On Rltd OrgsCompensationBasedOnRltdOrgsAmt	Bonus Filing OrganizationBonusFilingOrganizationAmount	Bonus Related OrganizationsBonusRelatedOrganizationsAmt	Other Compensation Filing OrgOtherCompensationFilingOrgAmt	Other Compensation Rltd OrgsOtherCompensationRltdOrgsAmt	Deferred Compensation Flng OrgDeferredCompensationFlngOrgAmt	Deferred Comp Rltd OrgsDeferredCompRltdOrgsAmt	Nontaxable Benefits Filing OrgNontaxableBenefitsFilingOrgAmt	Nontaxable Benefits Rltd OrgsNontaxableBenefitsRltdOrgsAmt	Total Compensation Filing OrgTotalCompensationFilingOrgAmt	Total Compensation Rltd OrgsTotalCompensationRltdOrgsAmt	Comp Report Prior990 Filing OrgCompReportPrior990FilingOrgAmt	Comp Report Prior990 Rltd OrgsCompReportPrior990RltdOrgsAmt
PETER G SCHULTZ
PRESIDENT/CEO	$936,865	$0	$838,321	$0	$9,394	$0	$42,250	$0	$32,410	$0	$1,859,240	$0	$0	$0
ERIC TOPOL
PROFESSOR/EXEC VP	$1,057,040	$0	$0	$0	$0	$0	$0	$0	$28,595	$0	$1,085,635	$0	$0	$0
CAROLINE MOON
CFO	$719,087	$0	$111,780	$0	$1,710	$0	$46,000	$0	$19,791	$0	$898,368	$0	$0	$0
MARSHALL OLIN
GENERAL COUNSEL	$395,270	$0	$275,235	$0	$1,706	$0	$45,854	$0	$28,312	$0	$746,377	$0	$0	$0
SCOTT SHOWALTER
CHIEF ADVANCEMENT OFFICER	$509,931	$0	$146,250	$0	$51,445	$0	$28,800	$0	$8,424	$0	$744,850	$0	$0	$0
CHANNING R BEALS
CHIEF MEDICAL OFFICER	$412,703	$0	$181,024	$0	$7,910	$0	$53,500	$0	$30,405	$0	$685,542	$0	$0	$0
TRAVIS SCOTT YOUNG
SR. DIRECTOR, CALIBR	$323,064	$0	$213,722	$0	$844	$0	$41,600	$0	$27,499	$0	$606,729	$0	$0	$0
JING LI
SENIOR DIRECTOR	$292,174	$0	$185,022	$0	$1,716	$0	$53,500	$0	$1,804	$0	$534,216	$0	$0	$0
KELLY SAN GEORGE
CFO VP ADM. CALIBR	$303,208	$0	$149,478	$0	$590	$0	$30,500	$0	$37,990	$0	$521,766	$0	$0	$0
BENJAMIN CRAVATT
FACULTY DIRECTOR (START 10/24)/PROF	$388,160	$0	$0	$0	$2,434	$0	$0	$0	$39,791	$0	$430,385	$0	$0	$0
JARED M MACHADO
TREASURER/CHIEF ACCOUNTING OFFICER	$321,589	$0	$48,904	$0	$1,328	$0	$23,000	$0	$29,864	$0	$424,685	$0	$0	$0
JAMES R WILLIAMSON
FRMR VP RES&ACAD AFFS(END 1/23)/PROF	$341,776	$0	$0	$0	$2,337	$0	$15,417	$0	$29,185	$0	$388,715	$0	$0	$0
ALANNA RUTAN
SECRETARY/CHIEF COMPLIANCE COUNSEL	$247,143	$0	$24,500	$0	$564	$0	$32,616	$0	$13,019	$0	$317,842	$0	$0	$0

Supplemental Information Detail SupplementalInformationDetail (2 entries)

Form And Line ReferenceFormAndLineReferenceDesc

ExplanationExplanationTxt

PART I, LINE 1A

BUSINESS TRAVEL AND FIRST CLASS TRAVEL. THE SCRIPPS RESEARCH INSTITUTE ALLOWS FOR BUSINESS TRAVEL FOR CERTAIN EMPLOYEES FOR LONG HAUL FLIGHTS. IN CERTAIN CIRCUMSTANCES, BUSINESS CLASS IS NOT AVAILABLE ON SMALLER AIRCRAFT. IN THOSE CIRCUMSTANCES, TSRI ALLOWS FIRST CLASS TRAVEL. THREE OFFICERS AND TWO HIGHEST COMPENSATED EMPLOYEES RECEIVED THIS BENEFIT, WHICH WAS NOT TREATED AS TAXABLE COMPENSATION TO THE INDIVIDUAL. HOUSING REIMBURSEMENT, WHICH IS TREATED AS TAXABLE COMPENSATION, WAS PROVIDED TO ONE OFFICER. TRAVEL FOR COMPANIONS, WHICH IS TREATED AS TAXABLE COMPENSATION, WAS PROVIDED TO ONE OFFICER. TAX GROSS-UPS ARE PROVIDED FOR HOUSING REIMBURSEMENTS AND TRAVEL FOR COMPANIONS. ONE OFFICER RECEIVED THIS BENEFIT, WHICH WAS TREATED AS TAXABLE COMPENSATION TO THE INDIVIDUAL. TAX GROSS-UPS ARE ALSO PROVIDED FOR RELOCATION. ONE HIGHEST COMPENSATED EMPLOYEE RECEIVED THIS BENEFIT, WHICH WAS TREATED AS TAXABLE COMPENSATION TO THE INDIVIDUAL.

FORM 990, PART VII, SECTION A, LINE 5 AND SCHEDULE J:

ERIC TOPOL, M.D., RECEIVED COMPENSATION FROM AN UNRELATED ORGANIZATION, SCRIPPS CLINIC MEDICAL GROUP, FOR SERVICES PROVIDED TO THE SCRIPPS RESEARCH INSTITUTE. IN 2024, IN EXCHANGE FOR THESE SERVICES, THE SCRIPPS RESEARCH INSTITUTE REIMBURSED THE SCRIPPS MEDICAL GROUP $750,000.

Schedule K IRS990ScheduleK

Tax Exempt Bonds Issues TaxExemptBondsIssuesGrp

Field	Value	IRS element (for citing)
Bond Reference	A	BondReferenceCd

Issuer Name IssuerName

Field	Value	IRS element (for citing)
Business Name Line1	CALIFORNIA INFRASTRUCTURE & ECONOMIC DEVELOPMENT BANK	BusinessNameLine1Txt

Field	Value	IRS element (for citing)
Bond Issuer EIN	630304653	BondIssuerEIN
CUSIP	13034AMU1	CUSIPNum
Bond Issued	2016-08-29	BondIssuedDt
Issue Price	$40,511,601	IssuePriceAmt
Purpose	SEE PART VI	PurposeDesc
Defeased	0	DefeasedInd
On Behalf Of Issuer	0	OnBehalfOfIssuerInd
Pool Financing	0	PoolFinancingInd

Tax Exempt Bonds Proceeds TaxExemptBondsProceedsGrp

Field	Value	IRS element (for citing)
Bond Reference	A	BondReferenceCd
Retired	$21,390,000	RetiredAmt
Total Proceeds	$40,511,601	TotalProceedsAmt
Issuance Costs From Proceeds	$648,703	IssuanceCostsFromProceedsAmt
Other Spent Proceeds	$39,862,898	OtherSpentProceedsAmt
Substantial Completion	2016	SubstantialCompletionYr
Refunding Tax Exempt Bonds	Yes (1)	RefundingTaxExemptBondsInd
Refunding Taxable Bonds	Yes (1)	RefundingTaxableBondsInd
Final Allocation Made	Yes (1)	FinalAllocationMadeInd
Adequate Books And Rec Maint	Yes (1)	AdequateBooksAndRecMaintInd

Tax Exempt Bonds Private Bus Use TaxExemptBondsPrivateBusUseGrp

Field	Value	IRS element (for citing)
Bond Reference	A	BondReferenceCd
Owning Bond Financed Property	0	OwningBondFinancedPropertyInd
Any Lease Arrangements	0	AnyLeaseArrangementsInd
Mgmt Contract Bond Fincd Prop	0	MgmtContractBondFincdPropInd
Any Research Agreements	Yes (1)	AnyResearchAgreementsInd
Engage Bond Counsel Research	0	EngageBondCounselResearchInd
Private Bus Use By Others	0.00000	PrivateBusUseByOthersPct
Private Bus Concerning UBI	0.00000	PrivateBusConcerningUBIPct
Total Private Business Use	0.00000	TotalPrivateBusinessUsePct
Bond Iss Meet Prvt Sec Pymt Test	0	BondIssMeetPrvtSecPymtTestInd
Change In Use Bond Financed Prop	0	ChangeInUseBondFinancedPropInd
Procs Nonqualified Bond Remdtd	Yes (1)	ProcsNonqualifiedBondRemdtdInd

Tax Exempt Bonds Arbitrage TaxExemptBondsArbitrageGrp

Field	Value	IRS element (for citing)
Bond Reference	A	BondReferenceCd
Form8038 T Filed	0	Form8038TFiledInd
Rebate Not Due Yet	0	RebateNotDueYetInd
Exception To Rebate	0	ExceptionToRebateInd
No Rebate Due	Yes (1)	NoRebateDueInd
Variable Rate Issue	0	VariableRateIssueInd
Hedge Identified In Bks And Rec	0	HedgeIdentifiedInBksAndRecInd
Gross Proceeds Invested In GIC	0	GrossProceedsInvestedInGICInd
Gross Proceeds Invested	0	GrossProceedsInvestedInd
Written Proc To Monitor Reqs	Yes (1)	WrittenProcToMonitorReqsInd

Procedures Corrective Action ProceduresCorrectiveActionGrp

Field	Value	IRS element (for citing)
Bond Reference	A	BondReferenceCd
Procedures Corrective Action	Yes (1)	ProceduresCorrectiveActionInd

Supplemental Information Detail SupplementalInformationDetail (4 entries)

Form And Line ReferenceFormAndLineReferenceDesc	ExplanationExplanationTxt
DATE REBATE COMPUTATION PERFORMED	ISSUER NAME: CALIFORNIA INFRASTRUCTURE & ECONOMIC DEVELOPMENT BANK DATE THE REBATE COMPUTATION WAS PERFORMED: 06/29/2022
SCHEDULE K, PART I, BOND ISSUES:	(A) ISSUE NAME: CALIFORNIA INFRASTRUCTURE & ECONOMIC DEVELOPMENT BANK (F) DESCRIPTION ON PURPOSE: REFUND AND DEFEASE BONDS PREVIOUSLY ISSUED FOR THE BENEFIT OF THE INSTITUTE ON 06/29/2000 AND 02/23/2005.
SCHEDULE K, PART III, LINE 3D:	OVERALL PRIVATE USE ISN'T MATERIAL, AND OUTSIDE COUNSEL WOULD REVIEW ANY SIGNIFICANT AGREEMENTS.
SCHEDULE K, PART IV, LINE 6:	THIS QUESTION IS BEING ANSWERED WITHOUT REGARD TO A YIELD-RESTRICTED ADVANCE REFUNDING ESCROW FINANCED WITH PROCEEDS OF THE BONDS.

Schedule M IRS990ScheduleM

Securities Publicly Traded SecuritiesPubliclyTradedGrp

Field	Value	IRS element (for citing)
Non Cash Checkbox	Yes (X)	NonCashCheckboxInd
Contribution	7	ContributionCnt
Noncash Contributions Rpt F990	$1,406,589	NoncashContributionsRptF990Amt
Method Of Determining Revenues	COST OR SELLING PRICE	MethodOfDeterminingRevenuesTxt

Field	Value	IRS element (for citing)
Form8283 Received	0	Form8283ReceivedCnt
Any Property That Must Be Held	0	AnyPropertyThatMustBeHeldInd
Review Process Unusual NC Gifts	Yes (1)	ReviewProcessUnusualNCGiftsInd
Third Parties Used	0	ThirdPartiesUsedInd

Supplemental Information Detail SupplementalInformationDetail

Field	Value	IRS element (for citing)
Form And Line Reference	PART I, COLUMN (B):	FormAndLineReferenceDesc
Explanation	NUMBER OF CONTRIBUTIONS OF PUBLICLY TRADED STOCK CONTRIBUTIONS	ExplanationTxt

Schedule O IRS990ScheduleO

Supplemental Information Detail SupplementalInformationDetail (5 entries)

Form And Line ReferenceFormAndLineReferenceDesc	ExplanationExplanationTxt
FORM 990, PART VI, SECTION B, LINE 11B	ON JUNE 2, 2026, THE AUDIT COMMITTEE REVIEWED A DRAFT OF THE FORM 990 (INCLUDING ALL SUPPLEMENTAL SCHEDULES). THIS REVIEW INCLUDED A PRESENTATION OF THE STATEMENTS BY THE STAFF WITH PARTICULAR EMPHASIS ON DISCLOSURES ABOUT GOVERNANCE. THE PRESENTATIONS TO THE AUDIT COMMITTEE DO NOT CONTAIN INFORMATION ABOUT TRANSACTIONS WITH INTERESTED PERSONS. TRANSACTIONS WITH INTERESTED PERSONS ARE PRESENTED TO THE FULL BOARD. THE 990 WILL BE PROVIDED TO THE FULL BOARD OF DIRECTORS PRIOR TO FILING.
FORM 990, PART VI, SECTION B, LINE 12C	TSRI'S CONFLICT OF INTEREST POLICIES AND PROCEDURES APPLY TO MEMBERS OF THE BOARD OF DIRECTORS, OFFICERS, KEY PERSONNEL, AND EMPLOYEES (ALTOGETHER COVERED INDIVIDUALS), REQUIRING DISCLOSURE OF CERTAIN FINANCIAL INTERESTS OF THE COVERED INVIDUAL AND THEIR FAMILY MEMBERS IN ORDER TO PROTECT THE INTERESTS OF TSRI WHEN IT IS CONTEMPLATING ENTERING INTO A TRANSACTION OR ARRANGEMENT THAT COULD: 1) BENEFIT THE PRIVATE INTEREST OF A COVERED INDIVIDUAL WITHIN THE MEANING OF TREASURY REGULATION SECTION 1.501(C)(3)-1(D)(1)(II), 2) RESULT IN A POSSIBLE EXCESS BENEFIT TRANSACTION WITHIN THE MEANING OF SECTION 4958(C) OF THE INTERNAL REVENUE CODE OF 1986, AS AMENDED; OR 3) BE A SELF-DEALING TRANSACTION WITHIN THE MEANING OF SECTION 5233 OF THE CALIFORNIA CORPORATIONS CODE (THE "CORPORATIONS CODE"). TSRI'S POLICIES AND PROCEDURES ARE INTENDED TO SUPPLEMENT, BUT NOT REPLACE, ANY STATE AND FEDERAL LAWS GOVERNING ACTUAL, POTENTIAL, OR APPARENT CONFLICT OF INTEREST APPLICABLE TO TSRI. DISCLOSURE DOCUMENTS RESPONSIVE TO TSRI'S POLICIES ARE ANNUALLY SUBMITTED BY COVERED INDIVIDUALS, AND ARE REVIEWED BY TSRI ADMINISTRATION FOR PERTINENT RELATIONSHIPS. ANY TRANSACTIONS OR ARRANGEMENTS INVOLVING COVERED INDIVIDUALS THAT FALL WITHIN THE SCOPE OF APPLICABLE STATE AND FEDERAL LAWS GOVERNING ACTUAL, POTENTIAL, OR APPARENT CONFLICT OF INTEREST ARE THEN SUBJECT TO REVIEW AND CONSIDERATION BY NON-CONFLICTED BOARD OF DIRECTOR MEMBERS, WITH CONFLICTED MEMBERS BEING RECUSED FROM ANY DEBATE AND VOTE TO APPROVE OR DISAPPROVE.
FORM 990, PART VI, SECTION B, LINE 15	THE COMPENSATION OF THE CEO AND CERTAIN OTHER KEY EXECUTIVES WAS REVIEWED AND APPROVED BY THE BOARD OF DIRECTORS. THIS REVIEW WAS BASED, IN PART, ON ANALYSIS PERFORMED BY THE HUMAN RESOURCES DEPARTMENT, AND INCLUDED DATA FROM OUTSIDE CONSULTANTS OR INTERNALLY-CONDUCTED RESEARCH. ON AN ONGOING BASIS, EXECUTIVES MAY PARTICIPATE IN THE NORMAL ANNUAL SALARY INCREASE PROGRAM, WHICH IS BASED ON A RECOMMENDATION FROM THE HUMAN RESOURCES DEPARTMENT BASED ON MARKET RESEARCH. ANY UNUSUAL OR POTENTIALLY NON-QUALIFIED COMPENSATION WOULD BE REVIEWED BY OUTSIDE COUNSEL FOR ANY TAX COMPLIANCE ISSUES.
FORM 990, PART VI, SECTION C, LINE 19	GOVERNING DOCUMENTS AND CONFLICT OF INTEREST POLICIES ARE NOT AVAILABLE TO THE PUBLIC AT THIS TIME. THE FINANCIAL STATEMENTS ARE PROVIDED TO BOND HOLDERS THROUGH TSRI'S DISSEMINATION AGENT. THE ANNUAL INFORMATION RETURN IS PROVIDED UPON REQUEST.
FORM 990, PART IX, LINE 11G	PURCHASED SERVICES & MAINTENANCE: PROGRAM SERVICE EXPENSES 71,517,926. MANAGEMENT AND GENERAL EXPENSES 0. FUNDRAISING EXPENSES 8,940. TOTAL EXPENSES 71,526,866.

Schedule R IRS990ScheduleR

Id Disregarded Entities IdDisregardedEntitiesGrp

Disregarded Entity Name DisregardedEntityName

Field	Value	IRS element (for citing)
Business Name Line1	STRIDE LLC	BusinessNameLine1Txt

US Address USAddress

Field	Value	IRS element (for citing)
Address Line1	10550 NORTH TORREY PINES ROAD	AddressLine1Txt
City	LA JOLLA	CityNm
State Abbreviation	CA	StateAbbreviationCd
ZIP	92037	ZIPCd

Field	Value	IRS element (for citing)
EIN	825129385	EIN
Primary Activities	FACILITATE BASIC RESEARCH	PrimaryActivitiesTxt
Legal Domicile State	CA	LegalDomicileStateCd
Total Income	$0	TotalIncomeAmt
End Of Year Assets	$0	EndOfYearAssetsAmt

Direct Controlling Entity Name DirectControllingEntityName

Field	Value	IRS element (for citing)
Business Name Line1	THE SCRIPPS RESEARCH INSTITUTE	BusinessNameLine1Txt

Id Related Org Txbl Corp Tr IdRelatedOrgTxblCorpTrGrp (3 entries)

Address Line1USAddress/AddressLine1Txt	CityUSAddress/CityNm	State AbbreviationUSAddress/StateAbbreviationCd	ZIPUSAddress/ZIPCd	EINEIN	Primary ActivitiesPrimaryActivitiesTxt	Legal Domicile StateLegalDomicileStateCd	Business Name Line1DirectControllingEntityName/BusinessNameLine1Txt	Entity TypeEntityTypeTxt	OwnershipOwnershipPct	Controlled OrganizationControlledOrganizationInd	Share Of Total IncomeShareOfTotalIncomeAmt	Share Of EOY AssetsShareOfEOYAssetsAmt
CALM THERAPEUTICS INC
10550 NORTH TORREY PINES ROAD	LA JOLLA	CA	92037	825375039	RESEARCH	CA	THE SCRIPPS RESEARCH INSTITUTE	S	0.62020	Yes (1)
OMRX ONCOLOGY INC
2033 GATEWAY PL SUITE 500	SAN JOSE	CA	95110	991650808	RESEARCH	CA	THE SCRIPPS RESEARCH INSTITUTE	C	0.70990	Yes (1)	$119,064	$5,154,352
CALIBR BIOVENTURES LLC
10550 NORTH TORREY PINES ROAD	LA JOLLA	CA	92037	862358499	RESEARCH	CA	THE SCRIPPS RESEARCH INSTITUTE	C	1.00000	Yes (1)	$1,665,311	$643,576

Field	Value	IRS element (for citing)
Receipt Of Int Annts Rnts Rylts	0	ReceiptOfIntAnntsRntsRyltsInd
Gift Grnt Or Cap Contri To Oth Org	Yes (1)	GiftGrntOrCapContriToOthOrgInd
Gift Grnt Cap Contri From Oth Org	0	GiftGrntCapContriFromOthOrgInd
Loans Or Guarantees To Other Org	0	LoansOrGuaranteesToOtherOrgInd
Loans Or Guarantees From Oth Org	0	LoansOrGuaranteesFromOthOrgInd
Div Related Organization	0	DivRelatedOrganizationInd
Asset Sale To Other Org	0	AssetSaleToOtherOrgInd
Asset Purchase From Other Org	0	AssetPurchaseFromOtherOrgInd
Asset Exchange	0	AssetExchangeInd
Rental Of Facilities To Oth Org	0	RentalOfFacilitiesToOthOrgInd
Rental Of Fclts From Oth Org	0	RentalOfFcltsFromOthOrgInd
Perform Of Services For Oth Org	0	PerformOfServicesForOthOrgInd
Perform Of Services By Other Org	Yes (1)	PerformOfServicesByOtherOrgInd
Sharing Of Facilities	0	SharingOfFacilitiesInd
Paid Employees Sharing	0	PaidEmployeesSharingInd
Reimbursement Paid To Other Org	0	ReimbursementPaidToOtherOrgInd
Reimbursement Paid By Other Org	0	ReimbursementPaidByOtherOrgInd
Transfer To Other Org	0	TransferToOtherOrgInd
Transfer From Other Org	0	TransferFromOtherOrgInd

Transactions Related Org TransactionsRelatedOrgGrp (2 entries)

Transaction TypeTransactionTypeTxt	InvolvedInvolvedAmt	Method Of Amount DeterminationMethodOfAmountDeterminationTxt
OMRX ONCOLOGY INC
B	$1,000,000	GENERAL LEDGER
CALIBR BIOVENTURES LLC
M	$1,335,381	GENERAL LEDGER