SCRIPPS RESEARCH INSTITUTE: Form 990, tax year 2021

View the entire original 990 at ProPublica ↗

Organization: SCRIPPS RESEARCH INSTITUTE (EIN 33-0435954)
Tax period: 2021-10-01 to 2022-09-30
Filed: 2023-08-15
IRS object ID: 202302279349303515
Schema version: 2021v4.2
Source: Download XML · Original 990 at ProPublica

Every field in the e-filed return. Faint text is the IRS element name, for citing.

Return header
Form 990
Schedule A
Schedule B
Schedule D
Schedule F
Schedule I
Schedule J
Schedule K
Schedule M
Schedule N
Schedule O
Schedule R

Return header ReturnHeader

Field	Value	IRS element (for citing)
Return	2023-08-15T14:10:49-05:00	ReturnTs
Tax Period End	2022-09-30	TaxPeriodEndDt

Preparer Firm PreparerFirmGrp

Field	Value	IRS element (for citing)
Preparer Firm EIN	861065772	PreparerFirmEIN

Preparer Firm Name PreparerFirmName

Field	Value	IRS element (for citing)
Business Name Line1	DELOITTE TAX LLP	BusinessNameLine1Txt

Preparer US Address PreparerUSAddress

Field	Value	IRS element (for citing)
Address Line1	695 TOWN CENTER DRIVE SUITE 1000	AddressLine1Txt
City	COSTA MESA	CityNm
State Abbreviation	CA	StateAbbreviationCd
ZIP	92626	ZIPCd

Field	Value	IRS element (for citing)
Return Type	990	ReturnTypeCd
Tax Period Begin	2021-10-01	TaxPeriodBeginDt

Filer Filer

Field	Value	IRS element (for citing)
EIN	330435954	EIN

Business Name BusinessName

Field	Value	IRS element (for citing)
Business Name Line1	THE SCRIPPS RESEARCH INSTITUTE	BusinessNameLine1Txt

Field	Value	IRS element (for citing)
Business Name Control	SCRI	BusinessNameControlTxt
Phone	8587841000	PhoneNum

US Address USAddress

Field	Value	IRS element (for citing)
Address Line1	10550 NORTH TORREY PINES ROAD	AddressLine1Txt
City	LA JOLLA	CityNm
State Abbreviation	CA	StateAbbreviationCd
ZIP	92037	ZIPCd

Business Officer BusinessOfficerGrp

Field	Value	IRS element (for citing)
Person	JARED MACHADO	PersonNm
Person Title	VP, TREAS. & CORP. FINANCE	PersonTitleTxt
Phone	8587849817	PhoneNum
Signature	2023-08-15	SignatureDt
Discuss With Paid Preparer	Yes (1)	DiscussWithPaidPreparerInd

Signing Officer SigningOfficerGrp

Person Full Name PersonFullName

Field	Value	IRS element (for citing)
Person First	JARED	PersonFirstNm
Person Last	MACHADO	PersonLastNm

Field	Value	IRS element (for citing)
SSN	XXX-XX-XXXX	SSN

Preparer Person PreparerPersonGrp

Field	Value	IRS element (for citing)
Preparer Person	JOHN W SADOFF JR	PreparerPersonNm
PTIN	P00540589	PTIN
Phone	7144367100	PhoneNum

Additional Filer Information AdditionalFilerInformation

Trusted Customer TrustedCustomerGrp

Field	Value	IRS element (for citing)
Trusted Customer	3	TrustedCustomerCd
Authentication Assurance Level	AAL1	AuthenticationAssuranceLevelCd
Identity Assurance Level	IAL1	IdentityAssuranceLevelCd

Field	Value	IRS element (for citing)
Tax	2021	TaxYr
Build TS	2023-04-26 12:10:37Z	BuildTS

Form 990 IRS990

Field	Value	IRS element (for citing)
Principal Officer	PETER SCHULTZ PHD	PrincipalOfficerNm

US Address USAddress

Field	Value	IRS element (for citing)
Address Line1	10550 NORTH TORREY PINES ROAD	AddressLine1Txt
City	LA JOLLA	CityNm
State Abbreviation	CA	StateAbbreviationCd
ZIP	92037	ZIPCd

Field	Value	IRS element (for citing)
Gross Receipts	$1,237,453,037	GrossReceiptsAmt
Group Return For Affiliates	0	GroupReturnForAffiliatesInd
Organization501c3	Yes (X)	Organization501c3Ind
Website Address	WWW.SCRIPPS.EDU	WebsiteAddressTxt
Type Of Organization Corp	Yes (X)	TypeOfOrganizationCorpInd
Formation	1924	FormationYr
Legal Domicile State	CA	LegalDomicileStateCd
Activity Or Mission	TSRI CONDUCTS BIOMEDICAL AND BIOCHEMICAL RESEARCH AND POSTGRADUATE TRAINING PROGRAMS.	ActivityOrMissionDesc
Contract Termination	Yes (X)	ContractTerminationInd
Voting Members Governing Body	17	VotingMembersGoverningBodyCnt
Voting Members Independent	15	VotingMembersIndependentCnt
Total Employee	2196	TotalEmployeeCnt
Total Volunteers	15	TotalVolunteersCnt
Total Gross UBI	$593,244	TotalGrossUBIAmt
Net Unrelated Bus Txbl Incm	$0	NetUnrelatedBusTxblIncmAmt
PY Contributions Grants	$418,691,076	PYContributionsGrantsAmt
CY Contributions Grants	$385,396,446	CYContributionsGrantsAmt
PY Program Service Revenue	$2,261,518	PYProgramServiceRevenueAmt
CY Program Service Revenue	$1,280,071	CYProgramServiceRevenueAmt
PY Investment Income	$39,422,523	PYInvestmentIncomeAmt
CY Investment Income	$96,765,180	CYInvestmentIncomeAmt
PY Other Revenue	$76,712,642	PYOtherRevenueAmt
CY Other Revenue	$151,538,720	CYOtherRevenueAmt
PY Total Revenue	$537,087,759	PYTotalRevenueAmt
CY Total Revenue	$634,980,417	CYTotalRevenueAmt
PY Grants And Similar Paid	$82,523,976	PYGrantsAndSimilarPaidAmt
CY Grants And Similar Paid	$467,412,781	CYGrantsAndSimilarPaidAmt
PY Benefits Paid To Members	$0	PYBenefitsPaidToMembersAmt
CY Benefits Paid To Members	$0	CYBenefitsPaidToMembersAmt
PY Salaries Comp Emp Bnft Paid	$217,363,929	PYSalariesCompEmpBnftPaidAmt
CY Salaries Comp Emp Bnft Paid	$238,179,882	CYSalariesCompEmpBnftPaidAmt
PY Total Prof Fndrsng Expns	$0	PYTotalProfFndrsngExpnsAmt
CY Total Prof Fndrsng Expns	$0	CYTotalProfFndrsngExpnsAmt
CY Total Fundraising Expense	$6,257,669	CYTotalFundraisingExpenseAmt
PY Other Expenses	$173,956,048	PYOtherExpensesAmt
CY Other Expenses	$179,368,979	CYOtherExpensesAmt
PY Total Expenses	$473,843,953	PYTotalExpensesAmt
CY Total Expenses	$884,961,642	CYTotalExpensesAmt
PY Revenues Less Expenses	$63,243,806	PYRevenuesLessExpensesAmt
CY Revenues Less Expenses	-$249,981,225	CYRevenuesLessExpensesAmt
Total Assets BOY	$1,160,188,604	TotalAssetsBOYAmt
Total Assets EOY	$828,320,768	TotalAssetsEOYAmt
Total Liabilities BOY	$438,180,180	TotalLiabilitiesBOYAmt
Total Liabilities EOY	$379,483,920	TotalLiabilitiesEOYAmt
Net Assets Or Fund Balances BOY	$722,008,424	NetAssetsOrFundBalancesBOYAmt
Net Assets Or Fund Balances EOY	$448,836,848	NetAssetsOrFundBalancesEOYAmt
Info In Schedule O Part III	Yes (X)	InfoInScheduleOPartIIIInd
Mission	THE SCRIPPS RESEARCH INSTITUTE ("TSRI") PERFORMS HIGH IMPACT BASIC BIOMEDICAL RESEARCH, IMPROVES THE HUMAN CONDITION BY FOSTERING TRANSLATION OF ITS DISCOVERIES INTO USEFUL PRODUCTS AND ENGAGES IN THE HIGHEST QUALITY GRADUATE SCIENTIFIC EDUCATION AND POST GRADUATE SCIENTIFIC TRAINING. TSRI IS KNOWN FOR ITS ENTREPRENEURIAL ENVIRONMENT AND ITS EMPHASIS IN RESEARCH RELATING TO SYNTHETIC CHEMISTRY, THE RELATIONSHIP BETWEEN MOLECULAR STRUCTURE AND ACTIVITY AND CHEMICAL BIOLOGY.	MissionDesc
Significant New Program Srvc	0	SignificantNewProgramSrvcInd
Significant Change	Yes (1)	SignificantChangeInd
Expense	$819,703,498	ExpenseAmt
Grant	$453,397,396	GrantAmt
Revenue	$1,280,071	RevenueAmt
Desc	GROUNDBREAKING SCIENTIFIC RESEARCH IS CONDUCTED AT TSRI CAMPUSES IN LA JOLLA, CALIFORNIA, AND JUPITER, FLORIDA, SUPPORTED BY GRANTS, CONTRACTS AND FELLOWSHIPS FROM PUBLIC AND PRIVATE INSTITUTES AND INDIVIDUALS. TSRI'S UNIQUE STRUCTURE MERGES BASIC SCIENTIFIC STUDIES IN BIOLOGY, CHEMISTRY AND BIOINFORMATICS WITH TRANSLATIONAL SCIENCE TO PRODUCE THE NEXT GENERATION OF DRUGS AND ADVANCES IN DIGITAL AND PRECISION MEDICINE. SCIENTIFIC DISCOVERIES AT TSRI SEED JOINT DRUG DISCOVERY PROJECTS AT CALIBR, A DIVISION OF TSRI, CREATING A PIPELINE OF DRUG CANDIDATES THAT WILL IMPACT PATIENTS FOR YEARS TO COME. THE SCRIPPS RESEARCH TRANSLATIONAL INSTITUTE, ANOTHER DIVISION OF TSRI, AIMS TO INDIVIDUALIZE HEALTHCARE BY LEVERAGING THE PROGRESS BEING MADE IN HUMAN GENOMICS AND COMBINING IT WITH THE POWER OF WIRELESS DIGITAL TECHNOLOGIES AND ARTIFICIAL INTELLIGENCE.	Desc

Prog Srvc Accom Acty2 ProgSrvcAccomActy2Grp

Field	Value	IRS element (for citing)
Expense	$26,322,909	ExpenseAmt
Grant	$14,015,385	GrantAmt
Desc	TSRI IS COMMITTED TO EDUCATING, TRAINING AND INSPIRING THE SCIENTISTS OF TOMORROW. THE INSTITUTE'S SKAGGS GRADUATE SCHOOL OF CHEMICAL AND BIOLOGICAL SCIENCES, RANKED ONE OF THE TEN BEST GRADUATE PROGRAMS IN THE COUNTRY, EMPOWERS STUDENTS TO MAKE HIGH-IMPACT DISCOVERIES AT THE INTERFACE OF CHEMISTRY AND BIOLOGY. STUDENTS IN THE SKAGGS GRADUATE SCHOOL ARE IMMERSED IN INTENSIVE LABORATORY RESEARCH FROM DAY ONE AND PURSUE AMBITIOUS INVESTIGATIONS ACROSS SCIENTIFIC DISCIPLINES. GRADUATES OF THE SCHOOL BECOME EDUCATORS AT TOP UNIVERSITIES AND RESEARCH INSTITUTES, THOUGHT LEADERS WITHIN GOVERNMENT DEPARTMENTS AND INNOVATORS AT PHARMACEUTICAL AND BIOTECHNOLOGY COMPANIES. POSTDOCTORAL ASSOCIATES ARRIVE AT TSRI FROM ALL OVER THE GLOBE, SEEKING TO EXPAND THEIR KNOWLEDGE AND TRAINING BY WORKING ALONGSIDE OUR WORLD-RENOWNED SCIENTISTS. THE SCRIPPS FELLOWS PROGRAM IDENTIFIES INDIVIDUALS WITH AN OUTSTANDING RECORD OF GRADUATE RESEARCH AND MOVES THEM INTO THEIR OWN LABORATORIES, ALLOWING THEM TO LEAPFROG THEIR POSTDOCTORAL YEARS OF STUDY AND BEGIN PUSHING THE FRONTIERS OF SCIENTIFIC DISCOVERY.	Desc

Field	Value	IRS element (for citing)
Total Program Service Expenses	$846,026,407	TotalProgramServiceExpensesAmt
Described In Section501c3	Yes (1)	DescribedInSection501c3Ind
Schedule B Required	Yes (1)	ScheduleBRequiredInd
Political Campaign Acty	0	PoliticalCampaignActyInd
Lobbying Activities	0	LobbyingActivitiesInd
Subject To Proxy Tax	0	SubjectToProxyTaxInd
Donor Advised Fund	0	DonorAdvisedFundInd
Conservation Easements	0	ConservationEasementsInd
Collections Of Art	0	CollectionsOfArtInd
Credit Counseling	0	CreditCounselingInd
Donor Rstr Or Quasi Endowments	Yes (1)	DonorRstrOrQuasiEndowmentsInd
Report Land Building Equipment	Yes (1)	ReportLandBuildingEquipmentInd
Report Investments Other Sec	Yes (1)	ReportInvestmentsOtherSecInd
Report Program Related Invst	0	ReportProgramRelatedInvstInd
Report Other Assets	0	ReportOtherAssetsInd
Report Other Liabilities	Yes (1)	ReportOtherLiabilitiesInd
Include FIN48 Footnote	0	IncludeFIN48FootnoteInd
Independent Audit Fincl Stmt	Yes (1)	IndependentAuditFinclStmtInd
Consolidated Audit Fincl Stmt	0	ConsolidatedAuditFinclStmtInd
School Operating	0	SchoolOperatingInd
Foreign Office	0	ForeignOfficeInd
Foreign Activities	Yes (1)	ForeignActivitiesInd
More Than5000 K To Org	Yes (1)	MoreThan5000KToOrgInd
More Than5000 K To Individuals	0	MoreThan5000KToIndividualsInd
Professional Fundraising	0	ProfessionalFundraisingInd
Fundraising Activities	0	FundraisingActivitiesInd
Gaming Activities	0	GamingActivitiesInd
Operate Hospital	0	OperateHospitalInd
Grants To Organizations	Yes (1)	GrantsToOrganizationsInd
Grants To Individuals	Yes (1)	GrantsToIndividualsInd
Schedule J Required	Yes (1)	ScheduleJRequiredInd
Tax Exempt Bonds	Yes (1)	TaxExemptBondsInd
Invest Tax Exempt Bonds	0	InvestTaxExemptBondsInd
Escrow Account	0	EscrowAccountInd
On Behalf Of Issuer	0	OnBehalfOfIssuerInd
Engaged In Excess Benefit Trans	0	EngagedInExcessBenefitTransInd
PY Excess Benefit Trans	0	PYExcessBenefitTransInd
Loan Outstanding	0	LoanOutstandingInd
Grant To Related Person	0	GrantToRelatedPersonInd
Business Rln With Org Mem	0	BusinessRlnWithOrgMemInd
Business Rln With Fam Mem	0	BusinessRlnWithFamMemInd
Business Rln With35 Ctrl Ent	0	BusinessRlnWith35CtrlEntInd
Deductible Non Cash Contri	Yes (1)	DeductibleNonCashContriInd
Deductible Art Contribution	0	DeductibleArtContributionInd
Terminate Operations	0	TerminateOperationsInd
Partial Liquidation	Yes (1)	PartialLiquidationInd
Disregarded Entity	Yes (1)	DisregardedEntityInd
Related Entity	Yes (1)	RelatedEntityInd
Related Organization Ctrl Ent	Yes (1)	RelatedOrganizationCtrlEntInd
Transaction With Control Ent	Yes (1)	TransactionWithControlEntInd
Trnsfr Exmpt Non Chrtbl Rltd Org	0	TrnsfrExmptNonChrtblRltdOrgInd
Activities Conducted Prtshp	0	ActivitiesConductedPrtshpInd
Schedule O Required	Yes (1)	ScheduleORequiredInd
IRP Document	339	IRPDocumentCnt
IRP Document W2 G	0	IRPDocumentW2GCnt
Backup Wthld Compliance	Yes (1)	BackupWthldComplianceInd
Employee	2196	EmployeeCnt
Employment Tax Returns Filed	Yes (1)	EmploymentTaxReturnsFiledInd
Unrelated Bus Incm Over Limit	Yes (1)	UnrelatedBusIncmOverLimitInd
Form990 T Filed	Yes (1)	Form990TFiledInd
Foreign Financial Account	0	ForeignFinancialAccountInd
Prohibited Tax Shelter Trans	0	ProhibitedTaxShelterTransInd
Taxable Party Notification	0	TaxablePartyNotificationInd
Nondeductible Contributions	0	NondeductibleContributionsInd
Quid Pro Quo Contributions	0	QuidProQuoContributionsInd
Form8282 Property Disposed Of	0	Form8282PropertyDisposedOfInd
Rcv Fnds To Pay Prsnl Bnft Cntrct	0	RcvFndsToPayPrsnlBnftCntrctInd
Pay Premiums Prsnl Bnft Cntrct	0	PayPremiumsPrsnlBnftCntrctInd
Indoor Tanning Services	0	IndoorTanningServicesInd
Subj To Tax Rmnrtn Ex Prcht Pymt	Yes (1)	SubjToTaxRmnrtnExPrchtPymtInd
Subject To Excs Tax Net Invst Inc	0	SubjectToExcsTaxNetInvstIncInd
Info In Schedule O Part VI	Yes (X)	InfoInScheduleOPartVIInd
Governing Body Voting Members	17	GoverningBodyVotingMembersCnt
Independent Voting Member	15	IndependentVotingMemberCnt
Family Or Business Rln	0	FamilyOrBusinessRlnInd
Delegation Of Mgmt Duties	0	DelegationOfMgmtDutiesInd
Change To Org Documents	0	ChangeToOrgDocumentsInd
Material Diversion Or Misuse	0	MaterialDiversionOrMisuseInd
Members Or Stockholders	0	MembersOrStockholdersInd
Election Of Board Members	0	ElectionOfBoardMembersInd
Decisions Subject To Approva	0	DecisionsSubjectToApprovaInd
Minutes Of Governing Body	Yes (1)	MinutesOfGoverningBodyInd
Minutes Of Committees	Yes (1)	MinutesOfCommitteesInd
Officer Mailing Address	0	OfficerMailingAddressInd
Local Chapters	0	LocalChaptersInd
Form990 Provided To Gvrn Body	Yes (1)	Form990ProvidedToGvrnBodyInd
Conflict Of Interest Policy	Yes (1)	ConflictOfInterestPolicyInd
Annual Disclosure Covered Prsn	Yes (1)	AnnualDisclosureCoveredPrsnInd
Regular Monitoring Enfrc	Yes (1)	RegularMonitoringEnfrcInd
Whistleblower Policy	Yes (1)	WhistleblowerPolicyInd
Document Retention Policy	Yes (1)	DocumentRetentionPolicyInd
Compensation Process CEO	Yes (1)	CompensationProcessCEOInd
Compensation Process Other	Yes (1)	CompensationProcessOtherInd
Investment In Joint Venture	0	InvestmentInJointVentureInd
States Where Copy Of Return Is Fld	AL	StatesWhereCopyOfReturnIsFldCd
States Where Copy Of Return Is Fld	AR	StatesWhereCopyOfReturnIsFldCd
States Where Copy Of Return Is Fld	CA	StatesWhereCopyOfReturnIsFldCd
States Where Copy Of Return Is Fld	CO	StatesWhereCopyOfReturnIsFldCd
States Where Copy Of Return Is Fld	DC	StatesWhereCopyOfReturnIsFldCd
States Where Copy Of Return Is Fld	FL	StatesWhereCopyOfReturnIsFldCd
States Where Copy Of Return Is Fld	GA	StatesWhereCopyOfReturnIsFldCd
States Where Copy Of Return Is Fld	HI	StatesWhereCopyOfReturnIsFldCd
States Where Copy Of Return Is Fld	IL	StatesWhereCopyOfReturnIsFldCd
States Where Copy Of Return Is Fld	KS	StatesWhereCopyOfReturnIsFldCd
States Where Copy Of Return Is Fld	KY	StatesWhereCopyOfReturnIsFldCd
States Where Copy Of Return Is Fld	MA	StatesWhereCopyOfReturnIsFldCd
States Where Copy Of Return Is Fld	MD	StatesWhereCopyOfReturnIsFldCd
States Where Copy Of Return Is Fld	MI	StatesWhereCopyOfReturnIsFldCd
States Where Copy Of Return Is Fld	MN	StatesWhereCopyOfReturnIsFldCd
States Where Copy Of Return Is Fld	MS	StatesWhereCopyOfReturnIsFldCd
States Where Copy Of Return Is Fld	NC	StatesWhereCopyOfReturnIsFldCd
States Where Copy Of Return Is Fld	NH	StatesWhereCopyOfReturnIsFldCd
States Where Copy Of Return Is Fld	NJ	StatesWhereCopyOfReturnIsFldCd
States Where Copy Of Return Is Fld	NM	StatesWhereCopyOfReturnIsFldCd
States Where Copy Of Return Is Fld	NY	StatesWhereCopyOfReturnIsFldCd
States Where Copy Of Return Is Fld	OH	StatesWhereCopyOfReturnIsFldCd
States Where Copy Of Return Is Fld	OR	StatesWhereCopyOfReturnIsFldCd
States Where Copy Of Return Is Fld	PA	StatesWhereCopyOfReturnIsFldCd
States Where Copy Of Return Is Fld	RI	StatesWhereCopyOfReturnIsFldCd
States Where Copy Of Return Is Fld	SC	StatesWhereCopyOfReturnIsFldCd
States Where Copy Of Return Is Fld	TN	StatesWhereCopyOfReturnIsFldCd
States Where Copy Of Return Is Fld	UT	StatesWhereCopyOfReturnIsFldCd
States Where Copy Of Return Is Fld	VA	StatesWhereCopyOfReturnIsFldCd
States Where Copy Of Return Is Fld	WI	StatesWhereCopyOfReturnIsFldCd
States Where Copy Of Return Is Fld	WV	StatesWhereCopyOfReturnIsFldCd
Upon Request	Yes (X)	UponRequestInd

Books In Care Of Detail BooksInCareOfDetail

Business Name BusinessName

Field	Value	IRS element (for citing)
Business Name Line1	JARED MACHADO	BusinessNameLine1Txt

Field	Value	IRS element (for citing)
Phone	8587841000	PhoneNum

US Address USAddress

Field	Value	IRS element (for citing)
Address Line1	10550 N TORREY PINES DRIVE	AddressLine1Txt
City	LA JOLLA	CityNm
State Abbreviation	CA	StateAbbreviationCd
ZIP	92037	ZIPCd

Form990 Part VII Section A Form990PartVIISectionAGrp (35 entries)

TitleTitleTxt	Average Hours Per WeekAverageHoursPerWeekRt	Average Hours Per Week Rltd OrgAverageHoursPerWeekRltdOrgRt	Individual Trustee Or DirectorIndividualTrusteeOrDirectorInd	OfficerOfficerInd	Reportable Comp From OrgReportableCompFromOrgAmt	Reportable Comp From Rltd OrgReportableCompFromRltdOrgAmt	Other CompensationOtherCompensationAmt	Key EmployeeKeyEmployeeInd	Highest Compensated EmployeeHighestCompensatedEmployeeInd	Former Ofcr Director TrusteeFormerOfcrDirectorTrusteeInd
PETER G SCHULTZ
PRESIDENT/CEO	40.00	0.00	Yes (X)	Yes (X)	$1,239,681	$0	$77,183
ARDEM PATAPOUTIAN
DIRECTOR/PROFESSOR (START 10/21)	9.20	0.00	Yes (X)		$82,916	$0	$16,583
BERNARD SAINT-DONAT PHD
DIRECTOR (END 10/21)	1.00	0.00	Yes (X)		$0	$0	$0
BENEDICT GROSS
DIRECTOR	1.00	0.00	Yes (X)		$0	$0	$0
CHRISTOPHER T WALSH
DIRECTOR (END 06/22)	1.00	0.00	Yes (X)		$0	$0	$0
CLAUDIA S LUTTRELL
DIRECTOR	1.00	0.00	Yes (X)		$0	$0	$0
GE LI
DIRECTOR	1.00	0.00	Yes (X)		$0	$0	$0
GERALD CHAN
DIRECTOR	1.00	0.00	Yes (X)		$0	$0	$0
HERBERT WERTHEIM
DIRECTOR	1.00	0.00	Yes (X)		$0	$0	$0
JEN RUBIO
DIRECTOR (START 1/22)	1.00	0.00	Yes (X)		$0	$0	$0
JOHN D DIEKMAN
BOARD CHAIR	1.00	0.00	Yes (X)		$0	$0	$0
JOANNE STUBBE
DIRECTOR	1.00	0.00	Yes (X)		$0	$0	$0
LILLIAN LOU
DIRECTOR	1.00	0.00	Yes (X)		$0	$0	$0
MARK EDWARDS
DIRECTOR	1.00	0.00	Yes (X)		$0	$0	$0
MARK PEARSON
DIRECTOR	1.00	0.00	Yes (X)		$0	$0	$0
PETER C FARRELL PHD D SC
DIRECTOR	1.00	0.00	Yes (X)		$0	$0	$0
RON BURKLE
DIRECTOR	1.00	0.00	Yes (X)		$0	$0	$0
SHERRY LANSING
DIRECTOR	1.00	0.00	Yes (X)		$0	$0	$0
TOM DANIEL
DIRECTOR	1.00	0.00	Yes (X)		$0	$0	$0
WILLIAM R HEARST III
DIRECTOR (END 01/22)	1.00	0.00	Yes (X)		$0	$0	$0
MATTHEW S TREMBLAY
CHIEF OPERATING OFFICER	40.00	0.00		Yes (X)	$707,113	$0	$80,213
ALICE T FENG
CFO & TREASURER (END 01/22)	40.00	0.00		Yes (X)	$393,039	$0	$78,157
JARED M MACHADO
TREAS.(BEG 1/22)/VP,TREAS.&CORP.FIN.	40.00	0.00		Yes (X)	$283,861	$0	$76,517
ALANNA RUTAN
SECRETARY/CHIEF COMPLIANCE OFFICER	40.00	0.00		Yes (X)	$234,041	$0	$42,444
MARY WANG
ASSISTANT SECRETARY/DIRECTOR SP	40.00	0.00		Yes (X)	$206,145	$0	$28,667
CAROLINE MOON
CFO (START 6/22)	40.00	0.00		Yes (X)	$0	$0	$0
JAMES R WILLIAMSON
VP RSCH & ACADEMIC AFFAIRS	40.00	0.00			$428,506	$0	$74,550	Yes (X)
KELLY SAN GEORGE
CFO VP ADM. CALIBR	40.00	0.00			$289,522	$0	$54,848	Yes (X)
DOUGLAS A BINGHAM
SECRETARY/EVP SCRIPPS FL (END 4/22)	40.00	0.00			$389,126	$0	$70,276	Yes (X)
ERIC TOPOL
PROFESSOR/EXEC VP	40.00	0.00			$1,236,257	$0	$72,958		Yes (X)
JIN-QUAN YU PHD
PROFESSOR	40.00	0.00			$416,175	$0	$76,161		Yes (X)
VADIM KLYUSHNICHENKO
VP PHARMACEUTICAL DEV & QUAL	40.00	0.00			$406,197	$0	$79,805		Yes (X)
TRAVIS SCOTT YOUNG
SR. DIRECTOR, CALIBR	40.00	0.00			$407,934	$0	$61,252		Yes (X)
PETER E WRIGHT
PROFESSOR	40.00	0.00			$378,893	$0	$73,516		Yes (X)
DEMETRIOS I ANDRIKOS
FORMER SECRETARY	0.40	0.00			$234,565	$0	$7,092			Yes (X)

Field	Value	IRS element (for citing)
Total Reportable Comp From Org	$7,333,971	TotalReportableCompFromOrgAmt
Tot Reportable Comp Rltd Org	$0	TotReportableCompRltdOrgAmt
Total Other Compensation	$970,222	TotalOtherCompensationAmt
Indiv Rcvd Greater Than100 K	359	IndivRcvdGreaterThan100KCnt
Former Ofcr Employees Listed	Yes (1)	FormerOfcrEmployeesListedInd
Total Comp Greater Than150 K	Yes (1)	TotalCompGreaterThan150KInd
Compensation From Other Srcs	Yes (1)	CompensationFromOtherSrcsInd

Contractor Compensation ContractorCompensationGrp (5 entries)

Address Line1ContractorAddress/USAddress/AddressLine1Txt	CityContractorAddress/USAddress/CityNm	State AbbreviationContractorAddress/USAddress/StateAbbreviationCd	ZIPContractorAddress/USAddress/ZIPCd	ServicesServicesDesc	CompensationCompensationAmt
BEHMER & BLACKFORD LLP
12526 HIGH BLUFF DRIVE SUITE 300	SAN DIEGO	CA	92130	LEGAL SERVICES	$1,318,311
WILSON SONSINI GOODRICH & ROSATI
PO BOX 742866	LOS ANGELES	CA	90074	LEGAL SERVICES	$1,198,824
SCHWEGMAN LUNDBERG WOESSNER PA
121 SOUTH EIGHTH STREET	MINNEAPOLIS	MN	55402	LEGAL SERVICES	$857,356
HOLLAND & KNIGHT LLP
PO BOX 864084	ORLANDO	FL	32886	LEGAL SERVICES	$477,698
DELOITTE & TOUCHE LLP
PO BOX 844708	DALLAS	TX	75284	AUDIT & TAX SERVICES	$469,852

Field	Value	IRS element (for citing)
Cntrct Rcvd Greater Than100 K	12	CntrctRcvdGreaterThan100KCnt
Government Grants	$242,135,467	GovernmentGrantsAmt
All Other Contributions	$143,260,979	AllOtherContributionsAmt
Noncash Contributions	$908,576	NoncashContributionsAmt
Total Contributions	$385,396,446	TotalContributionsAmt

Program Service Revenue ProgramServiceRevenueGrp

Field	Value	IRS element (for citing)
Desc	PATENT OFFICE	Desc
Business	900099	BusinessCd
Total Revenue Column	$1,280,071	TotalRevenueColumnAmt
Related Or Exempt Func Income	$1,280,071	RelatedOrExemptFuncIncomeAmt

Field	Value	IRS element (for citing)
Total Program Service Revenue	$1,280,071	TotalProgramServiceRevenueAmt

Investment Income InvestmentIncomeGrp

Field	Value	IRS element (for citing)
Total Revenue Column	$3,644,864	TotalRevenueColumnAmt
Unrelated Business Revenue	$593,244	UnrelatedBusinessRevenueAmt
Exclusion	$3,051,620	ExclusionAmt

Royalties Revenue RoyaltiesRevenueGrp

Field	Value	IRS element (for citing)
Total Revenue Column	$139,177,066	TotalRevenueColumnAmt
Exclusion	$139,177,066	ExclusionAmt

Gross Rents GrossRentsGrp

Field	Value	IRS element (for citing)
Real	$2,206,376	RealAmt

Less Rental Expenses LessRentalExpensesGrp

Field	Value	IRS element (for citing)
Real	$1,448,380	RealAmt

Rental Income Or Loss RentalIncomeOrLossGrp

Field	Value	IRS element (for citing)
Real	$757,996	RealAmt

Net Rental Income Or Loss NetRentalIncomeOrLossGrp

Field	Value	IRS element (for citing)
Total Revenue Column	$757,996	TotalRevenueColumnAmt
Exclusion	$757,996	ExclusionAmt

Gross Amount Sales Assets GrossAmountSalesAssetsGrp

Field	Value	IRS element (for citing)
Securities	$551,659,374	SecuritiesAmt
Other	$142,485,182	OtherAmt

Less Cost Oth Basis Sales Expnss LessCostOthBasisSalesExpnssGrp

Field	Value	IRS element (for citing)
Securities	$601,011,214	SecuritiesAmt
Other	$13,026	OtherAmt

Gain Or Loss GainOrLossGrp

Field	Value	IRS element (for citing)
Securities	-$49,351,840	SecuritiesAmt
Other	$142,472,156	OtherAmt

Net Gain Or Loss Investments NetGainOrLossInvestmentsGrp

Field	Value	IRS element (for citing)
Total Revenue Column	$93,120,316	TotalRevenueColumnAmt
Exclusion	$93,120,316	ExclusionAmt

Other Revenue Misc OtherRevenueMiscGrp (3 entries)

DescDesc	BusinessBusinessCd	Total Revenue ColumnTotalRevenueColumnAmt	ExclusionExclusionAmt
INSURANCE SETTLEMENT	900099	$6,100,000	$6,100,000
GRADUATE OFFICE COST R	900099	$3,114,551	$3,114,551
SHARED SRVCS-SCRIPPS H	900099	$569,762	$569,762

Miscellaneous Revenue MiscellaneousRevenueGrp

Field	Value	IRS element (for citing)
Total Revenue Column	$1,819,345	TotalRevenueColumnAmt
Exclusion	$1,819,345	ExclusionAmt

Field	Value	IRS element (for citing)
Other Revenue Total	$11,603,658	OtherRevenueTotalAmt

Total Revenue TotalRevenueGrp

Field	Value	IRS element (for citing)
Total Revenue Column	$634,980,417	TotalRevenueColumnAmt
Related Or Exempt Func Income	$1,280,071	RelatedOrExemptFuncIncomeAmt
Unrelated Business Revenue	$593,244	UnrelatedBusinessRevenueAmt
Exclusion	$247,710,656	ExclusionAmt

Field	Value	IRS element (for citing)
Info In Schedule O Part IX	Yes (X)	InfoInScheduleOPartIXInd

Grants To Domestic Orgs GrantsToDomesticOrgsGrp

Field	Value	IRS element (for citing)
Total	$451,905,079	TotalAmt
Program Services	$451,905,079	ProgramServicesAmt

Grants To Domestic Individuals GrantsToDomesticIndividualsGrp

Field	Value	IRS element (for citing)
Total	$14,015,385	TotalAmt
Program Services	$14,015,385	ProgramServicesAmt

Foreign Grants ForeignGrantsGrp

Field	Value	IRS element (for citing)
Total	$1,492,317	TotalAmt
Program Services	$1,492,317	ProgramServicesAmt

Comp Current Ofcr Directors CompCurrentOfcrDirectorsGrp

Field	Value	IRS element (for citing)
Total	$4,466,925	TotalAmt
Program Services	$1,167,030	ProgramServicesAmt
Management And General	$3,299,895	ManagementAndGeneralAmt

Other Salaries And Wages OtherSalariesAndWagesGrp

Field	Value	IRS element (for citing)
Total	$200,952,685	TotalAmt
Program Services	$183,507,489	ProgramServicesAmt
Management And General	$15,429,870	ManagementAndGeneralAmt
Fundraising	$2,015,326	FundraisingAmt

Pension Plan Contributions PensionPlanContributionsGrp

Field	Value	IRS element (for citing)
Total	-$7,619,867	TotalAmt
Program Services	-$6,899,495	ProgramServicesAmt
Management And General	-$650,390	ManagementAndGeneralAmt
Fundraising	-$69,982	FundraisingAmt

Other Employee Benefits OtherEmployeeBenefitsGrp

Field	Value	IRS element (for citing)
Total	$26,069,884	TotalAmt
Program Services	$24,498,701	ProgramServicesAmt
Management And General	$1,190,782	ManagementAndGeneralAmt
Fundraising	$380,401	FundraisingAmt

Payroll Taxes PayrollTaxesGrp

Field	Value	IRS element (for citing)
Total	$14,310,255	TotalAmt
Program Services	$12,957,382	ProgramServicesAmt
Management And General	$1,221,445	ManagementAndGeneralAmt
Fundraising	$131,428	FundraisingAmt

Fees For Services Management FeesForServicesManagementGrp

Field	Value	IRS element (for citing)
Total	$5,095,225	TotalAmt
Program Services	$5,095,225	ProgramServicesAmt

Fees For Services Legal FeesForServicesLegalGrp

Field	Value	IRS element (for citing)
Total	$8,308,743	TotalAmt
Program Services	$8,308,743	ProgramServicesAmt

Fees For Services Accounting FeesForServicesAccountingGrp

Field	Value	IRS element (for citing)
Total	$697,314	TotalAmt
Program Services	$697,314	ProgramServicesAmt

Fees For Services Other FeesForServicesOtherGrp

Field	Value	IRS element (for citing)
Total	$48,732,787	TotalAmt
Program Services	$45,623,842	ProgramServicesAmt
Management And General	$1,979,512	ManagementAndGeneralAmt
Fundraising	$1,129,433	FundraisingAmt

Office Expenses OfficeExpensesGrp

Field	Value	IRS element (for citing)
Total	$3,546,335	TotalAmt
Program Services	$3,214,975	ProgramServicesAmt
Management And General	$174,275	ManagementAndGeneralAmt
Fundraising	$157,085	FundraisingAmt

Occupancy OccupancyGrp

Field	Value	IRS element (for citing)
Total	$9,772,979	TotalAmt
Program Services	$7,617,417	ProgramServicesAmt
Management And General	$2,155,337	ManagementAndGeneralAmt
Fundraising	$225	FundraisingAmt

Travel TravelGrp

Field	Value	IRS element (for citing)
Total	$2,632,009	TotalAmt
Program Services	$2,423,546	ProgramServicesAmt
Management And General	$142,800	ManagementAndGeneralAmt
Fundraising	$65,663	FundraisingAmt

Interest InterestGrp

Field	Value	IRS element (for citing)
Total	$4,993,554	TotalAmt
Program Services	$4,993,554	ProgramServicesAmt

Depreciation Depletion DepreciationDepletionGrp

Field	Value	IRS element (for citing)
Total	$25,761,485	TotalAmt
Program Services	$25,759,046	ProgramServicesAmt
Fundraising	$2,439	FundraisingAmt

Insurance InsuranceGrp

Field	Value	IRS element (for citing)
Total	$3,021,755	TotalAmt
Program Services	$2,253,415	ProgramServicesAmt
Management And General	$5,466	ManagementAndGeneralAmt
Fundraising	$762,874	FundraisingAmt

Other Expenses OtherExpensesGrp (3 entries)

DescDesc	TotalTotalAmt	Program ServicesProgramServicesAmt	Management And GeneralManagementAndGeneralAmt	FundraisingFundraisingAmt
CONTRACTED SVCS - OTHER	$40,130,142	$34,806,547	$4,152,164	$1,171,431
LAB SUPPLIES	$15,352,319	$11,623,242	$3,576,410	$152,667
UTILITIES	$11,324,332	$10,965,653	$0	$358,679

Total Functional Expenses TotalFunctionalExpensesGrp

Field	Value	IRS element (for citing)
Total	$884,961,642	TotalAmt
Program Services	$846,026,407	ProgramServicesAmt
Management And General	$32,677,566	ManagementAndGeneralAmt
Fundraising	$6,257,669	FundraisingAmt

Savings And Temp Cash Invst SavingsAndTempCashInvstGrp

Field	Value	IRS element (for citing)
BOY	$196,423,177	BOYAmt
EOY	$150,464,867	EOYAmt

Pledges And Grants Receivable PledgesAndGrantsReceivableGrp

Field	Value	IRS element (for citing)
BOY	$73,942,523	BOYAmt
EOY	$59,315,416	EOYAmt

Accounts Receivable AccountsReceivableGrp

Field	Value	IRS element (for citing)
BOY	$483,949	BOYAmt
EOY	$3,859,762	EOYAmt

Oth Notes Loans Receivable Net OthNotesLoansReceivableNetGrp

Field	Value	IRS element (for citing)
BOY	$1,184,571	BOYAmt
EOY	$1,665,893	EOYAmt

Prepaid Expenses Defrd Charges PrepaidExpensesDefrdChargesGrp

Field	Value	IRS element (for citing)
BOY	$23,170,563	BOYAmt
EOY	$19,978,242	EOYAmt

Field	Value	IRS element (for citing)
Land Bldg Equip Cost Or Other Bss	$543,722,207	LandBldgEquipCostOrOtherBssAmt
Land Bldg Equip Accum Deprec	$380,185,787	LandBldgEquipAccumDeprecAmt

Land Bldg Equip Basis Net LandBldgEquipBasisNetGrp

Field	Value	IRS element (for citing)
BOY	$301,968,082	BOYAmt
EOY	$163,536,420	EOYAmt

Investments Pub Traded Sec InvestmentsPubTradedSecGrp

Field	Value	IRS element (for citing)
BOY	$291,006,964	BOYAmt
EOY	$173,859,658	EOYAmt

Investments Other Securities InvestmentsOtherSecuritiesGrp

Field	Value	IRS element (for citing)
BOY	$223,115,953	BOYAmt
EOY	$221,429,038	EOYAmt

Intangible Assets IntangibleAssetsGrp

Field	Value	IRS element (for citing)
BOY	$530,000	BOYAmt
EOY	$378,571	EOYAmt

Other Assets Total OtherAssetsTotalGrp

Field	Value	IRS element (for citing)
BOY	$48,362,822	BOYAmt
EOY	$33,832,901	EOYAmt

Total Assets TotalAssetsGrp

Field	Value	IRS element (for citing)
BOY	$1,160,188,604	BOYAmt
EOY	$828,320,768	EOYAmt

Accounts Payable Accr Expnss AccountsPayableAccrExpnssGrp

Field	Value	IRS element (for citing)
BOY	$79,866,253	BOYAmt
EOY	$70,685,226	EOYAmt

Deferred Revenue DeferredRevenueGrp

Field	Value	IRS element (for citing)
BOY	$166,769,573	BOYAmt
EOY	$141,358,103	EOYAmt

Tax Exempt Bond Liabilities TaxExemptBondLiabilitiesGrp

Field	Value	IRS element (for citing)
BOY	$24,615,041	BOYAmt
EOY	$20,889,555	EOYAmt

Mortg Notes Pybl Scrd Invst Prop MortgNotesPyblScrdInvstPropGrp

Field	Value	IRS element (for citing)
BOY	$106,075,000	BOYAmt
EOY	$105,920,000	EOYAmt

Other Liabilities OtherLiabilitiesGrp

Field	Value	IRS element (for citing)
BOY	$60,854,313	BOYAmt
EOY	$40,631,036	EOYAmt

Total Liabilities TotalLiabilitiesGrp

Field	Value	IRS element (for citing)
BOY	$438,180,180	BOYAmt
EOY	$379,483,920	EOYAmt

Field	Value	IRS element (for citing)
Organization Follows FASB117	Yes (X)	OrganizationFollowsFASB117Ind

No Donor Restriction Net Assets NoDonorRestrictionNetAssetsGrp

Field	Value	IRS element (for citing)
BOY	$448,091,646	BOYAmt
EOY	$213,749,076	EOYAmt

Donor Restriction Net Assets DonorRestrictionNetAssetsGrp

Field	Value	IRS element (for citing)
BOY	$273,916,778	BOYAmt
EOY	$235,087,772	EOYAmt

Total Net Assets Fund Balance TotalNetAssetsFundBalanceGrp

Field	Value	IRS element (for citing)
BOY	$722,008,424	BOYAmt
EOY	$448,836,848	EOYAmt

Tot Liab Net Assets Fund Balance TotLiabNetAssetsFundBalanceGrp

Field	Value	IRS element (for citing)
BOY	$1,160,188,604	BOYAmt
EOY	$828,320,768	EOYAmt

Field	Value	IRS element (for citing)
Reconcilation Revenue Expnss	-$249,981,225	ReconcilationRevenueExpnssAmt
Net Unrlzd Gains Losses Invst	-$23,190,351	NetUnrlzdGainsLossesInvstAmt
Other Changes In Net Assets	$0	OtherChangesInNetAssetsAmt
Method Of Accounting Accrual	Yes (X)	MethodOfAccountingAccrualInd
Accountant Compile Or Review	0	AccountantCompileOrReviewInd
FS Audited	Yes (1)	FSAuditedInd

FS Audited Basis FSAuditedBasisGrp

Field	Value	IRS element (for citing)
Separate Basis Fincl Stmt	Yes (X)	SeparateBasisFinclStmtInd

Field	Value	IRS element (for citing)
Audit Committee	Yes (1)	AuditCommitteeInd
Federal Grant Audit Required	Yes (1)	FederalGrantAuditRequiredInd
Federal Grant Audit Performed	Yes (1)	FederalGrantAuditPerformedInd

Schedule A IRS990ScheduleA

Field	Value	IRS element (for citing)
Public Organization170	Yes (X)	PublicOrganization170Ind

Gifts Grants Contri Rcvd170 GiftsGrantsContriRcvd170Grp

Field	Value	IRS element (for citing)
Current Tax Year Minus4 Years	$347,588,971	CurrentTaxYearMinus4YearsAmt
Current Tax Year Minus3 Years	$366,278,398	CurrentTaxYearMinus3YearsAmt
Current Tax Year Minus2 Years	$361,859,000	CurrentTaxYearMinus2YearsAmt
Current Tax Year Minus1 Year	$418,691,076	CurrentTaxYearMinus1YearAmt
Current Tax Year	$372,859,914	CurrentTaxYearAmt
Total	$1,867,277,359	TotalAmt

Total Calendar Year170 TotalCalendarYear170Grp

Field	Value	IRS element (for citing)
Current Tax Year Minus4 Years	$347,588,971	CurrentTaxYearMinus4YearsAmt
Current Tax Year Minus3 Years	$366,278,398	CurrentTaxYearMinus3YearsAmt
Current Tax Year Minus2 Years	$361,859,000	CurrentTaxYearMinus2YearsAmt
Current Tax Year Minus1 Year	$418,691,076	CurrentTaxYearMinus1YearAmt
Current Tax Year	$372,859,914	CurrentTaxYearAmt
Total	$1,867,277,359	TotalAmt

Field	Value	IRS element (for citing)
Substantial Contributors Tot	$131,981,604	SubstantialContributorsTotAmt
Public Support Total170	$1,735,295,755	PublicSupportTotal170Amt

Gross Investment Income170 GrossInvestmentIncome170Grp

Field	Value	IRS element (for citing)
Current Tax Year Minus4 Years	$22,130,806	CurrentTaxYearMinus4YearsAmt
Current Tax Year Minus3 Years	$36,426,682	CurrentTaxYearMinus3YearsAmt
Current Tax Year Minus2 Years	$33,129,194	CurrentTaxYearMinus2YearsAmt
Current Tax Year Minus1 Year	$77,075,770	CurrentTaxYearMinus1YearAmt
Current Tax Year	$145,028,308	CurrentTaxYearAmt
Total	$313,790,760	TotalAmt

Other Income170 OtherIncome170Grp

Field	Value	IRS element (for citing)
Current Tax Year Minus4 Years	$1,329,949	CurrentTaxYearMinus4YearsAmt
Current Tax Year Minus3 Years	$978,397	CurrentTaxYearMinus3YearsAmt
Current Tax Year Minus2 Years	$1,742,646	CurrentTaxYearMinus2YearsAmt
Current Tax Year Minus1 Year	$3,005,052	CurrentTaxYearMinus1YearAmt
Current Tax Year	$24,140,190	CurrentTaxYearAmt
Total	$31,196,234	TotalAmt

Field	Value	IRS element (for citing)
Total Support	$2,212,264,353	TotalSupportAmt
Gross Receipts Rltd Activities	$10,987,186	GrossReceiptsRltdActivitiesAmt
Public Support CY170	0.78440	PublicSupportCY170Pct
Public Support PY170	0.88290	PublicSupportPY170Pct
Thirty Thr Pct Suprt Tests CY170	Yes (X)	ThirtyThrPctSuprtTestsCY170Ind

Form990 Schedule A Part VI Form990ScheduleAPartVIGrp

Field	Value	IRS element (for citing)
Form And Line Reference	SCHEDULE A, PART II, LINE 10, EXPLANATION OF OTHER INCOME:	FormAndLineReferenceDesc
Explanation	OTHER INCOME - 2017 AMOUNT: $ 1,329,949. 2018 AMOUNT: $ 978,397. 2019 AMOUNT: $ 1,742,646. 2020 AMOUNT: $ 3,005,052. 2021 AMOUNT: $ 24,140,190.	ExplanationTxt

Schedule B IRS990ScheduleB

Contributor Information ContributorInformationGrp

Field	Value	IRS element (for citing)
Contributor	RESTRICTED	ContributorNum

Contributor Business Name ContributorBusinessName

Field	Value	IRS element (for citing)
Business Name Line1	RESTRICTED	BusinessNameLine1

Contributor US Address ContributorUSAddress

Field	Value	IRS element (for citing)
Address Line1	RESTRICTED	AddressLine1
Address Line2	RESTRICTED	AddressLine2
City	RESTRICTED	City
State	RESTRICTED	State
ZIP Code	RESTRICTED	ZIPCode

Field	Value	IRS element (for citing)
Total Contributions	RESTRICTED	TotalContributionsAmt

Schedule D IRS990ScheduleD

CY Endwmt Fund CYEndwmtFundGrp

Field	Value	IRS element (for citing)
Beginning Year Balance	$237,833,719	BeginningYearBalanceAmt
Contributions	$13,591,076	ContributionsAmt
Investment Earnings Or Losses	-$37,099,889	InvestmentEarningsOrLossesAmt
Other Expenditures	$9,648,746	OtherExpendituresAmt
End Year Balance	$204,676,160	EndYearBalanceAmt

CY Minus1 Yr Endwmt Fund CYMinus1YrEndwmtFundGrp

Field	Value	IRS element (for citing)
Beginning Year Balance	$198,444,686	BeginningYearBalanceAmt
Contributions	$22,060,000	ContributionsAmt
Investment Earnings Or Losses	$23,746,007	InvestmentEarningsOrLossesAmt
Other Expenditures	$6,416,974	OtherExpendituresAmt
End Year Balance	$237,833,719	EndYearBalanceAmt

CY Minus2 Yr Endwmt Fund CYMinus2YrEndwmtFundGrp

Field	Value	IRS element (for citing)
Beginning Year Balance	$181,126,346	BeginningYearBalanceAmt
Contributions	$12,474,348	ContributionsAmt
Investment Earnings Or Losses	$9,370,382	InvestmentEarningsOrLossesAmt
Other Expenditures	$4,526,390	OtherExpendituresAmt
End Year Balance	$198,444,686	EndYearBalanceAmt

CY Minus3 Yr Endwmt Fund CYMinus3YrEndwmtFundGrp

Field	Value	IRS element (for citing)
Beginning Year Balance	$166,946,785	BeginningYearBalanceAmt
Contributions	$15,554,839	ContributionsAmt
Investment Earnings Or Losses	$3,809,084	InvestmentEarningsOrLossesAmt
Other Expenditures	$5,184,362	OtherExpendituresAmt
End Year Balance	$181,126,346	EndYearBalanceAmt

CY Minus4 Yr Endwmt Fund CYMinus4YrEndwmtFundGrp

Field	Value	IRS element (for citing)
Beginning Year Balance	$136,651,781	BeginningYearBalanceAmt
Contributions	$29,186,503	ContributionsAmt
Investment Earnings Or Losses	$7,711,800	InvestmentEarningsOrLossesAmt
Other Expenditures	$6,603,299	OtherExpendituresAmt
End Year Balance	$166,946,785	EndYearBalanceAmt

Field	Value	IRS element (for citing)
Board Designated Balance EOY	0.07000	BoardDesignatedBalanceEOYPct
Prmnnt Endowment Balance EOY	0.66000	PrmnntEndowmentBalanceEOYPct
Term Endowment Balance EOY	0.27000	TermEndowmentBalanceEOYPct
Endowments Held Unrelated Org	0	EndowmentsHeldUnrelatedOrgInd
Endowments Held Related Org	0	EndowmentsHeldRelatedOrgInd

Land LandGrp

Field	Value	IRS element (for citing)
Other Cost Or Other Basis	$19,645,590	OtherCostOrOtherBasisAmt
Book Value	$19,645,590	BookValueAmt

Buildings BuildingsGrp

Field	Value	IRS element (for citing)
Other Cost Or Other Basis	$286,015,734	OtherCostOrOtherBasisAmt
Depreciation	$189,418,457	DepreciationAmt
Book Value	$96,597,277	BookValueAmt

Leasehold Improvements LeaseholdImprovementsGrp

Field	Value	IRS element (for citing)
Other Cost Or Other Basis	$22,651,825	OtherCostOrOtherBasisAmt
Depreciation	$21,964,280	DepreciationAmt
Book Value	$687,545	BookValueAmt

Equipment EquipmentGrp

Field	Value	IRS element (for citing)
Other Cost Or Other Basis	$209,947,812	OtherCostOrOtherBasisAmt
Depreciation	$164,980,510	DepreciationAmt
Book Value	$44,967,302	BookValueAmt

Other Land Buildings OtherLandBuildingsGrp

Field	Value	IRS element (for citing)
Other Cost Or Other Basis	$5,461,246	OtherCostOrOtherBasisAmt
Depreciation	$3,822,540	DepreciationAmt
Book Value	$1,638,706	BookValueAmt

Field	Value	IRS element (for citing)
Total Book Value Land Buildings	$163,536,420	TotalBookValueLandBuildingsAmt

Other Securities OtherSecuritiesGrp

Field	Value	IRS element (for citing)
Desc	INVESTMENT IN LIMITED PARTNERSHIPS	Desc
Book Value	$221,429,038	BookValueAmt
Method Valuation	F	MethodValuationCd

Field	Value	IRS element (for citing)
Total Book Value Securities	$221,429,038	TotalBookValueSecuritiesAmt

Other Liabilities Org OtherLiabilitiesOrgGrp (3 entries)

DescDesc	AmtAmt
PENSION LIABILITY	$6,687,740
LEASE LIABILITY	$33,689,592
UNITRUST	$253,704

Field	Value	IRS element (for citing)
Total Liability	$40,631,036	TotalLiabilityAmt
Total Rev Etc Audited Fincl Stmt	$613,213,684	TotalRevEtcAuditedFinclStmtAmt
Net Unrealized Gains Invst	-$23,190,351	NetUnrealizedGainsInvstAmt
Other Revenue	$1,423,618	OtherRevenueAmt
Revenue Not Reported	-$21,766,733	RevenueNotReportedAmt
Revenue Subtotal	$634,980,417	RevenueSubtotalAmt
Revenue Not Reported Fincl Stmt	$0	RevenueNotReportedFinclStmtAmt
Total Revenue Per Form990	$634,980,417	TotalRevenuePerForm990Amt
Tot Expns Etc Audited Fincl Stmt	$886,386,678	TotExpnsEtcAuditedFinclStmtAmt
Other Expenses Included	$1,425,036	OtherExpensesIncludedAmt
Expenses Not Reported	$1,425,036	ExpensesNotReportedAmt
Expenses Subtotal	$884,961,642	ExpensesSubtotalAmt
Expenses Not Rpt Fincl Stmt	$0	ExpensesNotRptFinclStmtAmt
Total Expenses Per Form990	$884,961,642	TotalExpensesPerForm990Amt

Supplemental Information Detail SupplementalInformationDetail (3 entries)

Form And Line ReferenceFormAndLineReferenceDesc	ExplanationExplanationTxt
PART V, LINE 4:	INVESTMENT RETURN FROM THE ENDOWMENTS SUPPORTS SCIENTIFIC PROJECTS CONSISTENT WITH THE MISSION AND PRINCIPLES OF THE SCRIPPS RESEARCH INSTITUTE.
PART XI, LINE 2D - OTHER ADJUSTMENTS:	RENTAL EXPENSES NETTED AGAINST RENTAL REVENUE 1,448,380. GAIN ON DISPOSAL OF EQUIPMENT -24,762.
PART XII, LINE 2D - OTHER ADJUSTMENTS:	RENTAL EXPENSES NETTED AGAINST RENTAL REVENUE 1,448,380. GAIN ON DISPOSAL OF EQUIPMENT -24,762. ROUNDING 1,418.

Schedule F IRS990ScheduleF

Field	Value	IRS element (for citing)
Grant Records Maintained	Yes (1)	GrantRecordsMaintainedInd

Account Activities Outside US AccountActivitiesOutsideUSGrp (5 entries)

RegionRegionTxt	Type Of Activities ConductedTypeOfActivitiesConductedTxt	Specific Services ProvidedSpecificServicesProvidedTxt	Region Total ExpendituresRegionTotalExpendituresAmt
EAST ASIA AND THE PACIFIC	PROGRAM SERVICES	GRANTS FOR SCIENTIFIC RESEARCH	$53,139
EUROPE (INCLUDING ICELAND & GREENLAND)	PROGRAM SERVICES	GRANTS FOR SCIENTIFIC RESEARCH	$999,529
NORTH AMERICA	PROGRAM SERVICES	GRANTS FOR SCIENTIFIC RESEARCH	$69,790
SUB-SAHARAN AFRICA	PROGRAM SERVICES	GRANTS FOR SCIENTIFIC RESEARCH	$369,859
CENTRAL AMERICA AND THE CARIBBEAN	INVESTMENTS		$70,088,060

Field	Value	IRS element (for citing)
Subtotal Offices	0	SubtotalOfficesCnt
Subtotal Employees	0	SubtotalEmployeesCnt
Continuation Total Office	0	ContinuationTotalOfficeCnt
Continuation Total Employee	0	ContinuationTotalEmployeeCnt
Total Office	0	TotalOfficeCnt
Total Employee	0	TotalEmployeeCnt
Subtotal Spent	$71,580,377	SubtotalSpentAmt
Continuation Spent	$0	ContinuationSpentAmt
Total Spent	$71,580,377	TotalSpentAmt

Grants To Org Outside US GrantsToOrgOutsideUSGrp (12 entries)

RegionRegionTxt	Purpose Of GrantPurposeOfGrantTxt	Cash GrantCashGrantAmt	Manner Of Cash DisbursementMannerOfCashDisbursementTxt	Non Cash AssistanceNonCashAssistanceAmt
NORTH AMERICA	GRANTS FOR SCIENTIFIC RESEARCH	$69,790	CHECK	$0
EUROPE (INCLUDING ICELAND & GREENLAND)	GRANTS FOR SCIENTIFIC RESEARCH	$481,723	ELECTRONIC FUND/WIRE TRANSFER	$0
SUB-SAHARAN AFRICA	GRANTS FOR SCIENTIFIC RESEARCH	$98,595	ELECTRONIC FUND/WIRE TRANSFER	$0
EAST ASIA AND THE PACIFIC	GRANTS FOR SCIENTIFIC RESEARCH	$53,139	ELECTRONIC FUND/WIRE TRANSFER	$0
SUB-SAHARAN AFRICA	GRANTS FOR SCIENTIFIC RESEARCH	$41,499	ELECTRONIC FUND/WIRE TRANSFER	$0
SUB-SAHARAN AFRICA	GRANTS FOR SCIENTIFIC RESEARCH	$77,119	ELECTRONIC FUND/WIRE TRANSFER	$0
SUB-SAHARAN AFRICA	GRANTS FOR SCIENTIFIC RESEARCH	$19,967	ELECTRONIC FUND/WIRE TRANSFER	$0
EUROPE (INCLUDING ICELAND & GREENLAND)	GRANTS FOR SCIENTIFIC RESEARCH	$126,673	ELECTRONIC FUND/WIRE TRANSFER	$0
EUROPE (INCLUDING ICELAND & GREENLAND)	GRANTS FOR SCIENTIFIC RESEARCH	$198,391	ELECTRONIC FUND/WIRE TRANSFER	$0
EUROPE (INCLUDING ICELAND & GREENLAND)	GRANTS FOR SCIENTIFIC RESEARCH	$86,902	ELECTRONIC FUND/WIRE TRANSFER	$0
EUROPE (INCLUDING ICELAND & GREENLAND)	GRANTS FOR SCIENTIFIC RESEARCH	$105,840	CHECK	$0
SUB-SAHARAN AFRICA	GRANTS FOR SCIENTIFIC RESEARCH	$132,679	ELECTRONIC FUND/WIRE TRANSFER	$0

Field	Value	IRS element (for citing)
Total501c3 Org	12	Total501c3OrgCnt
Total Other Org	0	TotalOtherOrgCnt
Transfer To Foreign Corp	Yes (1)	TransferToForeignCorpInd
Interest In Foreign Trust	0	InterestInForeignTrustInd
Foreign Corp Ownership	Yes (1)	ForeignCorpOwnershipInd
Passive Foreign Investmest Co	0	PassiveForeignInvestmestCoInd
Foreign Partnership	Yes (1)	ForeignPartnershipInd
Boycott Countries	0	BoycottCountriesInd

Supplemental Information Detail SupplementalInformationDetail (3 entries)

Form And Line ReferenceFormAndLineReferenceDesc	ExplanationExplanationTxt
PART I, LINE 2:	TSRI MONITORS THE AMOUNTS PROVIDED TO THE FOREIGN ORGANIZATION BY ADHERENCE TO A GRANT CONTRACT AND MONITORS DETAILED BILLING STATEMENTS OF RESEARCH EXPENDITURES.
PART III ACCOUNTING METHOD:
SCHEDULE F, PART IV:	TSRI HAS LESS THAN 10% OWNERSHIP IN A FOREIGN CORPORATION DURING THE TAX YEAR, AND THEREFORE, WAS NOT REQUIRED TO FILE FORM 5471.

Schedule I IRS990ScheduleI

Field	Value	IRS element (for citing)
Grant Records Maintained	Yes (1)	GrantRecordsMaintainedInd

Recipient Table RecipientTable (94 entries)

Address Line1USAddress/AddressLine1Txt	CityUSAddress/CityNm	State AbbreviationUSAddress/StateAbbreviationCd	ZIPUSAddress/ZIPCd	Recipient EINRecipientEIN	IRC SectionIRCSectionDesc	Cash GrantCashGrantAmt	Non Cash AssistanceNonCashAssistanceAmt	Purpose Of GrantPurposeOfGrantTxt	Valuation Method UsedValuationMethodUsedDesc	Non Cash AssistanceNonCashAssistanceDesc
ACTIVE MINDS INC
2001 S STREET NW SUITE 630	WASHINGTON	DC	20009	200587172	501(C)(3)	$180,462	$0	GRANTS FOR SCIENTIFIC RESEARCH
ALBERT EINSTEIN COLLEGE OF MEDICINE
1300 MORRIS PARK AVE	BRONX	NY	10461	830621846	501(C)(3)	$126,119	$0	GRANTS FOR SCIENTIFIC RESEARCH
AMERICAN COLLEGE HEALTH ASSOCIATION
1362 MELLON RD STE 180	HANOVER	MD	21076	362681352	501(C)(3)	$150,423	$0	GRANTS FOR SCIENTIFIC RESEARCH
APPLIED BIOMEDICAL SCIENCE INSTITUTE
11011 VIA FRONTERA STE D	SAN DIEGO	CA	92127	825056708	501(C)(3)	$500,837	$0	GRANTS FOR SCIENTIFIC RESEARCH
BANNER HEALTH
2901 N CENTRAL AVE 160	PHOENIX	AZ	85012	450233470	501(C)(3)	$26,948	$0	GRANTS FOR SCIENTIFIC RESEARCH
BAYLOR COLLEGE OF MEDICINE
ONE BAYLOR PLAZA MS BCM160	HOUSTON	TX	77030	741613878	501(C)(3)	$54,890	$0	GRANTS FOR SCIENTIFIC RESEARCH
BLOOD ASSURANCE INC
705 E 3RD STREET	CHATTANOOGA	TN	37403	620842419	501(C)(3)	$28,622	$0	GRANTS FOR SCIENTIFIC RESEARCH
BLOODWORKS NORTHWEST
921 TERRY AVE	SEATTLE	WA	98104	911019655	501(C)(3)	$749,601	$0	GRANTS FOR SCIENTIFIC RESEARCH
BLUE CROSS BLUE SHIELD
225 N MICHIGAN AVE	CHICAGO	IL	60601	135656874	501(C)(3)	$403,849	$0	GRANTS FOR SCIENTIFIC RESEARCH
BOSTON UNIVERSITY
ONE SILBER WAY	BOSTON	MA	02215	042103547	501(C)(3)	$254,825	$0	GRANTS FOR SCIENTIFIC RESEARCH
BRIGHAM YOUNG UNIVERSITY
A-153 ASB	PROVO	UT	84602	870217280	501(C)(3)	$382,570	$0	GRANTS FOR SCIENTIFIC RESEARCH
BROAD INSTITUTE
415 MAIN ST	CAMBRIDGE	MA	02142	263428781	501(C)(3)	$461,430	$0	GRANTS FOR SCIENTIFIC RESEARCH
CARE EVOLUTION
625 N MAIN ST	ANN ARBOR	MI	48104	731677920		$4,065,276	$0	GRANTS FOR SCIENTIFIC RESEARCH
CASCADE REGIONAL BLOOD SERVICES
220 SOUTH I ST	TACOMA	WA	98405	910657805	501(C)(3)	$5,532	$0	GRANTS FOR SCIENTIFIC RESEARCH
CASE WESTERN RESERVE UNIVERSITY
10900 EUCLID AVENUE	CLEVELAND	OH	44106	341018922	501(C)(3)	$13,315	$0	GRANTS FOR SCIENTIFIC RESEARCH
CESSATION THERAPEUTICS
3031 TISCH WAY STE 505	SAN JOSE	CA	95128	823906297		$9,719	$0	GRANTS FOR SCIENTIFIC RESEARCH
COLUMBIA UNIVERISTY
622 WEST 113TH STREET MAIL CODE 452	NEW YORK	NY	10025	135598093	501(C)(3)	$96,303	$0	GRANTS FOR SCIENTIFIC RESEARCH
DEDALUS HEALTHCARE SYSTEMS GROUP
3411 SILVERSIDE ROAD	WILMINGTON	DE	19810	952043126		$3,765,242	$0	GRANTS FOR SCIENTIFIC RESEARCH
DENVER HEALTH & HOSPITAL AUTHORITY
777 BANNOCK STREET	DENVER	CO	80204	841343242	501(C)(3)	$206,604	$0	GRANTS FOR SCIENTIFIC RESEARCH
EMORY UNIVERSITY
1762 CLIFTON RD STE 1400	ATLANTA	GA	30322	580566256	501(C)(3)	$1,581,057	$0	GRANTS FOR SCIENTIFIC RESEARCH
FITBIT INC
199 FREMONT STREET 14TH FLOOR	SAN FRANCISCO	CA	94105	208920744		$610,062	$0	GRANTS FOR SCIENTIFIC RESEARCH
FLORIDA STATE UNIVERSITY
319 STADIUM DR	TALLAHASSEE	FL	32306	591961248	501(C)(3)	$78,998	$0	GRANTS FOR SCIENTIFIC RESEARCH
FRED HUTCHINSON CANCER RESEARCH CENTER
1100 FAIRVIEW AVE N PO BOX 19024	SEATTLE	WA	98109	237156071	501(C)(3)	$1,159,087	$0	GRANTS FOR SCIENTIFIC RESEARCH
GEORGIA TECH RESEARCH CORPORATION
926 DALNEY ST NW	ATLANTA	GA	30318	580603146	501(C)(3)	$311,295	$0	GRANTS FOR SCIENTIFIC RESEARCH
GULF COAST REGIONAL BLOOD CENTER
1400 LA CONCA LANE	HOUSTON	TX	77054	741809687	501(C)(3)	$17,738	$0	GRANTS FOR SCIENTIFIC RESEARCH
H LEE MOFFITT CANCER CENTER
12902 MAGNOLIA DRIVE	TAMPA	FL	33612	592451713	501(C)(3)	$83,489	$0	GRANTS FOR SCIENTIFIC RESEARCH
HARVARD MEDICAL SCHOOL
25 SHATTUCK ST	BOSTON	MA	02115	042213292	501(C)(3)	$801,724	$0	GRANTS FOR SCIENTIFIC RESEARCH
HIV & AGING RESEARCH PROJECT PS
1775 E PALM CANYON DR STE 110-349	PALM SPRINGS	CA	92264	473892886	501(C)(3)	$45,430	$0	GRANTS FOR SCIENTIFIC RESEARCH
ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI
ONE GUSTAVE L LEVY PLACE BOX 1049	NEW YORK	NY	10029	136171197	501(C)(3)	$33,508	$0	GRANTS FOR SCIENTIFIC RESEARCH
INTERNATIONAL AIDS VACCINE INITIATIVE
125 BROAD STREET 9TH FLOOR	NEW YORK	NY	10004	133870223	501(C)(3)	$7,216,413	$0	GRANTS FOR SCIENTIFIC RESEARCH
J DAVID GLADSTONE INSTITUTE
1650 OWENS STREET	SAN FRANCISCO	CA	94158	277203666	501(C)(3)	$422,549	$0	GRANTS FOR SCIENTIFIC RESEARCH
JOHNS HOPKINS UNIVERSITY
3910 KESWICK ROAD SUITE N2100	BALTIMORE	MD	21211	520595110	501(C)(3)	$401,807	$0	GRANTS FOR SCIENTIFIC RESEARCH
LA JOLLA INSTITUTE FOR IMMUNOLOGY
9420 ATHENA CIRCLE	LA JOLLA	CA	92037	330328688	501(C)(3)	$2,491,108	$0	GRANTS FOR SCIENTIFIC RESEARCH
LEHIGH UNIVERSITY
306 SOUTH NEW STREET SUITE 500	BETHLEHEM	PA	18015	240795445	501(C)(3)	$83,057	$0	GRANTS FOR SCIENTIFIC RESEARCH
MARY'S CENTER FOR MATERNAL & CHILD CARE
2333 ONTARIO RD NW	WASHINGTON	DC	20009	521594116	501(C)(3)	$229,626	$0	GRANTS FOR SCIENTIFIC RESEARCH
MASSACHUSETTS GENERAL HOSPITAL
125 NASHUA STREET SUITE 540	BOSTON	MA	02114	041564655	501(C)(3)	$2,769,117	$0	GRANTS FOR SCIENTIFIC RESEARCH
MASSACHUSETTS INSTITUE OF TECHNOLOGY
77 MASSACHUSETTS AVE NE49-31	CAMBRIDGE	MA	02139	042103594	501(C)(3)	$1,403,105	$0	GRANTS FOR SCIENTIFIC RESEARCH
MAYO CLINIC JACKSONVILLE
200 1ST ST SW	ROCHESTER	MN	55905	593337028	501(C)(3)	$174,887	$0	GRANTS FOR SCIENTIFIC RESEARCH
MICHIGAN STATE UNIVERSITY
535 CHESTNUT RD RM 300	EAST LANSING	MI	48824	386005984	501(C)(3)	$22,259	$0	GRANTS FOR SCIENTIFIC RESEARCH
MONTAGE MARKETING GROUP
5714 ABERDEEN RD	BETHESDA	MD	20814	472971390		$2,540,703	$0	GRANTS FOR SCIENTIFIC RESEARCH
NORTHWESTERN UNIVERSITY
633 CLARK ST	EVANSTON	IL	60208	362167817	501(C)(3)	$93,471	$0	GRANTS FOR SCIENTIFIC RESEARCH
OWAVES INC
3633 CAMINO DEL RIO SOUTH 210	SAN DIEGO	CA	92108	453566351		$1,105,334	$0	GRANTS FOR SCIENTIFIC RESEARCH
PATIENTS LIKE ME INC
160 2ND STREET	CAMBRIDGE	MA	02142	202310011		$32,150	$0	GRANTS FOR SCIENTIFIC RESEARCH
PROSETTA BIOSCIENCES
670 5TH STREET	SAN FRANCISCO	CA	94107	464080003		$176,634	$0	GRANTS FOR SCIENTIFIC RESEARCH
PUBLIC HEALTH INSTITUE
555 12TH STREET 6TH FLOOR	OAKLAND	CA	94607	941646278	501(C)(3)	$58,671	$0	GRANTS FOR SCIENTIFIC RESEARCH
RADY CHILDREN'S INSTITUTE FOR GENOMIC MEDICINE
3020 CHILDRENS WAY MC5129	SAN DIEGO	CA	92123	951691313	501(C)(3)	$263,732	$0	GRANTS FOR SCIENTIFIC RESEARCH
RTI INTERNATIONAL
PO BOX 12194	RESEARCH TRIANGLE PARK	NC	27709	560686338	501(C)(3)	$97,869	$0	GRANTS FOR SCIENTIFIC RESEARCH
SAGE BIONETWORKS
2901 3RD AVE STE 330	SEATTLE	WA	98121	264489946	501(C)(3)	$2,362,495	$0	GRANTS FOR SCIENTIFIC RESEARCH
SAN DIEGO BIOMEDICAL RESEARCH INSTITUTE
3525 JOHN HOPKINS CT STE 200	SAN DIEGO	CA	92121	463481092	501(C)(3)	$340,746	$0	GRANTS FOR SCIENTIFIC RESEARCH
SAN DIEGO BLOOD BANK
3636 GATEWAY CENTER AVENUE STE 10	SAN DIEGO	CA	92102	951696732	501(C)(3)	$1,287,626	$0	GRANTS FOR SCIENTIFIC RESEARCH
SAN DIEGO STATE UNIVERSITY RESEARCH FOUNDATION
5200 CAMPANILE DRIVE	SAN DIEGO	CA	92182	956042721	501(C)(3)	$46,254	$0	GRANTS FOR SCIENTIFIC RESEARCH
SANFORD BURNHAM PREBYS
10901 N TORREY PINES RD	LA JOLLA	CA	92037	510197108	501(C)(3)	$83,410	$0	GRANTS FOR SCIENTIFIC RESEARCH
SCHEPENS EYE RESEARCH INSTITUTE
399 REVOLUTION DR STE 645	SOMERVILLE	MA	02145	042129889	501(C)(3)	$46,360	$0	GRANTS FOR SCIENTIFIC RESEARCH
SCINTILLON INSTITUTE
6868 NANCY RIDGE DR	SAN DIEGO	CA	92121	454323888	501(C)(3)	$48,463	$0	GRANTS FOR SCIENTIFIC RESEARCH
SCRIPPS HEALTH
PO BOX 2669	LA JOLLA	CA	92038	951684089	501(C)(3)	$981,306	$0	GRANTS FOR SCIENTIFIC RESEARCH
SEATTLE CHILDREN'S RESEARCH INSTITUTE
1900 9TH AVE	SEATTLE	WA	98101	910564748	501(C)(3)	$522,646	$0	GRANTS FOR SCIENTIFIC RESEARCH
SENSIS INC
818 S BROADWAY SUITE 1100	LOS ANGELES	CA	90014	202484749		$371,284	$0	GRANTS FOR SCIENTIFIC RESEARCH
SOUTH TEXAS BLOOD & TISSUE
6211 IH 10 WEST	SAN ANTONIO	TX	78201	237379332	501(C)(3)	$140,290	$0	GRANTS FOR SCIENTIFIC RESEARCH
STANFORD UNIVERSITY
485 BROADWAY MAIL CODE 8838	REDWOOD CITY	CA	94063	941156365	501(C)(3)	$2,113,872	$0	GRANTS FOR SCIENTIFIC RESEARCH
TEXAS BIOMEDICAL RESEARCH INSTITUTE
PO BOX 760549	SAN ANTONIO	TX	78245	741109630	501(C)(3)	$304,262	$0	GRANTS FOR SCIENTIFIC RESEARCH
THE JACKSON LABORATORY
PO BOX 254	BAR HARBOR	ME	04609	010211513	501(C)(3)	$129,780	$0	GRANTS FOR SCIENTIFIC RESEARCH
THE ROCKEFELLER UNIVERISTY
1230 YORK AVE	NEW YORK	NY	10065	131624158	501(C)(3)	$701,036	$0	GRANTS FOR SCIENTIFIC RESEARCH
THE SALK INSTITUTE FOR BIOLOGICAL STUDIES
10010 N TORREY PINES RD	LA JOLLA	CA	92037	952160097	501(C)(3)	$143,071	$0	GRANTS FOR SCIENTIFIC RESEARCH
THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL
103 SOUTH BUILDING CAMPUS BOX 9100	CHAPEL HILL	NC	27599	566001393	501(C)(3)	$58,605	$0	GRANTS FOR SCIENTIFIC RESEARCH
TULANE UNIVERSITY
6823 ST CHARLES AVENUE	NEW ORLEANS	LA	70118	720423889	501(C)(3)	$545,583	$0	GRANTS FOR SCIENTIFIC RESEARCH
UNIV OF CALIFORNIA - DAVIS
202 COUSTEAU PL STE 185	DAVIS	CA	95618	946036494	501(C)(3)	$745,671	$0	GRANTS FOR SCIENTIFIC RESEARCH
UNIV OF CALIFORNIA - IRVINE
120 THEORY STE 200	IRVINE	CA	92617	952226406	501(C)(3)	$46,407	$0	GRANTS FOR SCIENTIFIC RESEARCH
UNIV OF CALIFORNIA - LOS ANGELES
10889 WILSHIRE BOULEVARD STE 700	LOS ANGELES	CA	90095	956006143	501(C)(3)	$701,098	$0	GRANTS FOR SCIENTIFIC RESEARCH
UNIV OF CALIFORNIA - SAN DIEGO
9500 GILMAN DR	LA JOLLA	CA	92093	956006144	501(C)(3)	$2,607,272	$0	GRANTS FOR SCIENTIFIC RESEARCH
UNIV OF MARYLAND BALTIMORE
650 W BALTIMORE ST	BALTIMORE	MD	21201	526002033	501(C)(3)	$29,042	$0	GRANTS FOR SCIENTIFIC RESEARCH
UNIV OF PENNSYLVANIA
125 S 31ST STE 2000	PHILADELPHIA	PA	19104	231352685	501(C)(3)	$413,112	$0	GRANTS FOR SCIENTIFIC RESEARCH
UNIVERSITY OF ALABAMA-BIRMINGHAM
703 SOUTH 19TH STREET	BIRMINGHAM	AL	35294	636005396	GOVT	$154,260	$0	GRANTS FOR SCIENTIFIC RESEARCH
UNIVERSITY OF ARIZONA
PO BOX 41867	TUCSON	AZ	85717	742652689	GOVT	$127,679	$0	GRANTS FOR SCIENTIFIC RESEARCH
UNIVERSITY OF FLORIDA
BOX 100266	GAINESVILLE	FL	32610	596002052	501(C)(3)	$88,206,830	$307,976,835	GRANTS FOR SCIENTIFIC RESEARCH AND EDUCATION	APPRAISAL	SCRIPPS FLORIDA RESEARCH FACILITY
UNIVERSITY OF GEORGIA RESEARCH FOUNDATION
324 BUSINESS SRVCS 456 E BROAD ST	ATHENS	GA	30602	581353149	501(C)(3)	$384,484	$0	GRANTS FOR SCIENTIFIC RESEARCH
UNIVERSITY OF GUAM
UOG STATION	MANGILAO	GU	96923	980032933	GOVT	$28,886	$0	GRANTS FOR SCIENTIFIC RESEARCH
UNIVERSITY OF ILLINOIS URBANA-CHAMPAIGN
506 S WRIGHT 209 HAB MC-339	URBANA	IL	61801	376000511	501(C)(3)	$97,816	$0	GRANTS FOR SCIENTIFIC RESEARCH
UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL
333 SOUTH STREET SUITE 450	SHREWSBURY	MA	01545	043167352	501(C)(3)	$164,055	$0	GRANTS FOR SCIENTIFIC RESEARCH
UNIVERSITY OF MIAMI
PO BOX 248106	CORAL GABLES	FL	33124	590624458	501(C)(3)	$299,485	$0	GRANTS FOR SCIENTIFIC RESEARCH
UNIVERSITY OF MICHIGAN
515 E JEFFERSON	ANN ARBOR	MI	48109	386006309	501(C)(3)	$81,785	$0	GRANTS FOR SCIENTIFIC RESEARCH
UNIVERSITY OF PITTSBURGH
128 NORTH CRAIG STREET	PITTSBURGH	PA	15260	250965591	501(C)(3)	$66,248	$0	GRANTS FOR SCIENTIFIC RESEARCH
UNIVERSITY OF ROCHESTER
910 GENESEE ST STE 200	ROCHESTER	NY	14611	160743209	501(C)(3)	$36,825	$0	GRANTS FOR SCIENTIFIC RESEARCH
UNIVERSITY OF SOUTHERN CALIFORNIA
3551 TROUSDALE PARKWAY STE 160	LOS ANGELES	CA	90089	951642394	501(C)(3)	$118,581	$0	GRANTS FOR SCIENTIFIC RESEARCH
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER
5323 HARRY HINES BLVD	DALLAS	TX	75390	756002868	501(C)(3)	$701,528	$0	GRANTS FOR SCIENTIFIC RESEARCH
UNIVERSITY OF UTAH
201 S PRESIDENTS CIR RM 145	SALT LAKE CITY	UT	84112	876000525	501(C)(3)	$25,794	$0	GRANTS FOR SCIENTIFIC RESEARCH
UNIVERSITY OF VIRGINIA
PO BOX 400195	CHARLOTTESVILLE	VA	22904	546001796	501(C)(3)	$49,362	$0	GRANTS FOR SCIENTIFIC RESEARCH
UNIVERSITY OF WASHINGTON
4295 EAST STEVENS WAY NE	SEATTLE	WA	98195	916001537	501(C)(3)	$58,981	$0	GRANTS FOR SCIENTIFIC RESEARCH
UNIVERSITY OF WISCONSIN
21 N PARK STREET SUITE 6301	MADISON	WI	53715	396006492	501(C)(3)	$408,046	$0	GRANTS FOR SCIENTIFIC RESEARCH
URBAN ONE INC
1010 WAYNE AVE	SILVER SPRING	MD	20910	521166660		$35,000	$0	GRANTS FOR SCIENTIFIC RESEARCH
VANDERBILT UNIVERSITY MEDICAL CENTER
3322 WEST END AVENUE SUITE 900	NASHVILLE	TN	37203	352528741	501(C)(3)	$88,777	$0	GRANTS FOR SCIENTIFIC RESEARCH
VETERANS MEDICAL RESEARCH FOUNDATION
3350 LA JOLLA VILLAGE DR 151A	SAN DIEGO	CA	92161	330189397	501(C)(3)	$264,637	$0	GRANTS FOR SCIENTIFIC RESEARCH
WALGREENS
108 WILMOT ROAD	DEERFIELD	IL	60015	471758322		$947,034	$0	GRANTS FOR SCIENTIFIC RESEARCH
WEB MD
395 HUDSON STREET	NEW YORK	NY	10014	202783228		$862,500	$0	GRANTS FOR SCIENTIFIC RESEARCH
YALE UNIVERSITY
PO BOX 2038	NEW HAVEN	CT	06521	060646973	501(C)(3)	$158,976	$0	GRANTS FOR SCIENTIFIC RESEARCH

Field	Value	IRS element (for citing)
Total501c3 Org	82	Total501c3OrgCnt
Total Other Org	12	TotalOtherOrgCnt

Grants Other Asst To Indiv In US GrantsOtherAsstToIndivInUSGrp

Field	Value	IRS element (for citing)
Grant Type	SCHOLARSHIPS & STIPENDS, TSRI GRADUATE SCHOOL	GrantTypeTxt
Recipient	346	RecipientCnt
Cash Grant	$14,015,385	CashGrantAmt

Supplemental Information Detail SupplementalInformationDetail

Field	Value	IRS element (for citing)
Form And Line Reference	PART I, LINE 2:	FormAndLineReferenceDesc
Explanation	TSRI MONITORS THE AMOUNTS PROVIDED TO THE DOMESTIC ORGANIZATION BY ADHERENCE TO A GRANT CONTRACT AND MONITORS DETAILED BILLING STATEMENTS OF RESEARCH EXPENDITURES. GRADUATE STUDENT STIPENDS ARE PROCESSED VIA PERSONNEL ACTION FORMS WHICH ARE APPROVED BY THE GRADUATE OFFICE AND HUMAN RESOURCES PRIOR TO BEING SENT TO THE PAYROLL OFFICE. ONCE APPROVED, GRADUATE STUDENTS ARE SET UP IN TSRI'S PAYROLL SYSTEM AND ARE DISPERSED ON THE 1ST AND 15TH OF EACH MONTH. MONITORING IS DONE VIA THE INTERACTION BETWEEN THE STUDENT AND FACULTY ADVISOR. AS LONG AS THE STUDENT IS PROGRESSING, SHE/HE WOULD CONTINUE TO BE PAID.	ExplanationTxt

Schedule J IRS990ScheduleJ

Field	Value	IRS element (for citing)
First Class Or Charter Travel	Yes (X)	FirstClassOrCharterTravelInd
Written Policy Ref T And E Expnss	Yes (1)	WrittenPolicyRefTAndEExpnssInd
Substantiation Required	Yes (1)	SubstantiationRequiredInd
Independent Consultant	Yes (X)	IndependentConsultantInd
Form990 Of Other Organizations	Yes (X)	Form990OfOtherOrganizationsInd
Compensation Survey	Yes (X)	CompensationSurveyInd
Board Or Committee Approval	Yes (X)	BoardOrCommitteeApprovalInd
Severance Payment	Yes (1)	SeverancePaymentInd
Supplemental Nonqual Rtr Plan	0	SupplementalNonqualRtrPlanInd
Equity Based Comp Arrngm	0	EquityBasedCompArrngmInd
Comp Based On Revenue Of Flng Org	0	CompBasedOnRevenueOfFlngOrgInd
Comp Bsd On Rev Related Orgs	0	CompBsdOnRevRelatedOrgsInd
Comp Bsd Net Earns Flng Org	0	CompBsdNetEarnsFlngOrgInd
Comp Bsd Net Earns Rltd Orgs	0	CompBsdNetEarnsRltdOrgsInd
Any Non Fixed Payments	0	AnyNonFixedPaymentsInd
Initial Contract Exception	0	InitialContractExceptionInd

Rltd Org Officer Trst Key Empl RltdOrgOfficerTrstKeyEmplGrp (15 entries)

TitleTitleTxt	Base Compensation Filing OrgBaseCompensationFilingOrgAmt	Compensation Based On Rltd OrgsCompensationBasedOnRltdOrgsAmt	Bonus Filing OrganizationBonusFilingOrganizationAmount	Bonus Related OrganizationsBonusRelatedOrganizationsAmt	Other Compensation Filing OrgOtherCompensationFilingOrgAmt	Other Compensation Rltd OrgsOtherCompensationRltdOrgsAmt	Deferred Compensation Flng OrgDeferredCompensationFlngOrgAmt	Deferred Comp Rltd OrgsDeferredCompRltdOrgsAmt	Nontaxable Benefits Filing OrgNontaxableBenefitsFilingOrgAmt	Nontaxable Benefits Rltd OrgsNontaxableBenefitsRltdOrgsAmt	Total Compensation Filing OrgTotalCompensationFilingOrgAmt	Total Compensation Rltd OrgsTotalCompensationRltdOrgsAmt	Comp Report Prior990 Filing OrgCompReportPrior990FilingOrgAmt	Comp Report Prior990 Rltd OrgsCompReportPrior990RltdOrgsAmt
PETER G SCHULTZ
PRESIDENT/CEO	$819,463	$0	$391,421	$0	$28,797	$0	$58,000	$0	$19,183	$0	$1,316,864	$0	$0	$0
ERIC TOPOL
PROFESSOR/EXEC VP	$1,235,689	$0	$0	$0	$568	$0	$58,000	$0	$14,958	$0	$1,309,215	$0	$0	$0
MATTHEW S TREMBLAY
CHIEF OPERATING OFFICER	$514,490	$0	$190,675	$0	$1,948	$0	$58,000	$0	$22,213	$0	$787,326	$0	$0	$0
JAMES R WILLIAMSON
VP RSCH & ACADEMIC AFFAIRS	$382,732	$0	$38,403	$0	$7,371	$0	$58,000	$0	$16,550	$0	$503,056	$0	$0	$0
JIN-QUAN YU PHD
PROFESSOR	$401,638	$0	$0	$0	$14,537	$0	$58,000	$0	$18,161	$0	$492,336	$0	$0	$0
VADIM KLYUSHNICHENKO
VP PHARMACEUTICAL DEV & QUAL	$257,491	$0	$80,275	$0	$68,431	$0	$58,000	$0	$21,805	$0	$486,002	$0	$0	$0
ALICE T FENG
CFO & TREASURER (END 01/22)	$302,284	$0	$36,001	$0	$54,754	$0	$58,000	$0	$20,157	$0	$471,196	$0	$0	$0
TRAVIS SCOTT YOUNG
SR. DIRECTOR, CALIBR	$263,867	$0	$133,000	$0	$11,067	$0	$41,701	$0	$19,551	$0	$469,186	$0	$0	$0
DOUGLAS A BINGHAM
SECRETARY/EVP SCRIPPS FL (END 4/22)	$319,848	$0	$29,122	$0	$40,156	$0	$58,000	$0	$12,276	$0	$459,402	$0	$0	$0
PETER E WRIGHT
PROFESSOR	$368,790	$0	$0	$0	$10,103	$0	$58,000	$0	$15,516	$0	$452,409	$0	$0	$0
JARED M MACHADO
TREAS.(BEG 1/22)/VP,TREAS.&CORP.FIN.	$227,038	$0	$26,000	$0	$30,823	$0	$52,420	$0	$24,097	$0	$360,378	$0	$0	$0
KELLY SAN GEORGE
CFO VP ADM. CALIBR	$203,930	$0	$57,512	$0	$28,080	$0	$35,259	$0	$19,589	$0	$344,370	$0	$0	$0
ALANNA RUTAN
SECRETARY/CHIEF COMPLIANCE OFFICER	$191,224	$0	$26,876	$0	$15,941	$0	$29,900	$0	$12,544	$0	$276,485	$0	$0	$0
DEMETRIOS I ANDRIKOS
FORMER SECRETARY	$22,568	$0	$0	$0	$211,997	$0	$5,500	$0	$1,592	$0	$241,657	$0	$0	$0
MARY WANG
ASSISTANT SECRETARY/DIRECTOR SP	$151,327	$0	$42,670	$0	$12,148	$0	$16,348	$0	$12,319	$0	$234,812	$0	$0	$0

Supplemental Information Detail SupplementalInformationDetail (3 entries)

Form And Line ReferenceFormAndLineReferenceDesc	ExplanationExplanationTxt
PART I, LINE 1A	BUSINESS TRAVEL AND FIRST CLASS TRAVEL. THE SCRIPPS RESEARCH INSTITUTE ALLOWS FOR BUSINESS TRAVEL FOR CERTAIN KEY EMPLOYEES FOR LONG HAUL FLIGHTS. IN CERTAIN CIRCUMSTANCES, BUSINESS CLASS IS NOT AVAILABLE ON SMALLER AIRCRAFT. IN THOSE CIRCUMSTANCES, TSRI ALLOWS FIRST CLASS TRAVEL.
PART I, LINE 4A	SEVERANCE IS PROVIDED TO CERTAIN DEPARTING EMPLOYEES AND IS DETERMINED BASED ON LEVEL AND YEARS OF SERVICE AT THE INSTITUTE AS WELL AS THE INSTITUTE'S NEED TO ACCESS THE DEPARTED EMPLOYEE FOR TRANSITION PURPOSES. DEMETRIOS I. ANDRIKOS RECEIVED A SEVERANCE PAYMENT OF $160,000 DURING 2021.
OTHER INFORMATION RELATED TO FORM 990, PART VII, LINE 5:	ERIC TOPOL, M.D., RECEIVED COMPENSATION FROM AN UNRELATED ORGANIZATION, SCRIPPS CLINIC MEDICAL GROUP, FOR SERVICES PROVIDED TO THE SCRIPPS RESEARCH INSTITUTE. IN 2021, IN EXCHANGE FOR THESE SERVICES, THE SCRIPPS RESEARCH INSTITUTE REIMBURSED THE SCRIPPS MEDICAL GROUP $937,500.

Schedule K IRS990ScheduleK

Tax Exempt Bonds Issues TaxExemptBondsIssuesGrp

Field	Value	IRS element (for citing)
Bond Reference	A	BondReferenceCd

Issuer Name IssuerName

Field	Value	IRS element (for citing)
Business Name Line1	CALIFORNIA INFRASTRUCTURE & ECONOMIC DEVELOPMENT BANK	BusinessNameLine1Txt

Field	Value	IRS element (for citing)
Bond Issuer EIN	630304653	BondIssuerEIN
CUSIP	13034AMU1	CUSIPNum
Bond Issued	2016-08-30	BondIssuedDt
Issue Price	$40,511,601	IssuePriceAmt
Purpose	SEE PART VI	PurposeDesc
Defeased	0	DefeasedInd
On Behalf Of Issuer	0	OnBehalfOfIssuerInd
Pool Financing	0	PoolFinancingInd

Tax Exempt Bonds Proceeds TaxExemptBondsProceedsGrp

Field	Value	IRS element (for citing)
Bond Reference	A	BondReferenceCd
Retired	$14,105,000	RetiredAmt
Total Proceeds	$40,511,601	TotalProceedsAmt
Refunding Escrow	$1,103,259	RefundingEscrowAmt
Issuance Costs From Proceeds	$648,704	IssuanceCostsFromProceedsAmt
Other Spent Proceeds	$39,236,172	OtherSpentProceedsAmt
Substantial Completion	2016	SubstantialCompletionYr
Refunding Tax Exempt Bonds	Yes (1)	RefundingTaxExemptBondsInd
Refunding Taxable Bonds	Yes (1)	RefundingTaxableBondsInd
Final Allocation Made	Yes (1)	FinalAllocationMadeInd
Adequate Books And Rec Maint	Yes (1)	AdequateBooksAndRecMaintInd

Tax Exempt Bonds Private Bus Use TaxExemptBondsPrivateBusUseGrp

Field	Value	IRS element (for citing)
Bond Reference	A	BondReferenceCd
Owning Bond Financed Property	0	OwningBondFinancedPropertyInd
Any Lease Arrangements	0	AnyLeaseArrangementsInd
Mgmt Contract Bond Fincd Prop	0	MgmtContractBondFincdPropInd
Any Research Agreements	Yes (1)	AnyResearchAgreementsInd
Engage Bond Counsel Research	0	EngageBondCounselResearchInd
Private Bus Use By Others	0.00000	PrivateBusUseByOthersPct
Private Bus Concerning UBI	0.00000	PrivateBusConcerningUBIPct
Total Private Business Use	0.00000	TotalPrivateBusinessUsePct
Bond Iss Meet Prvt Sec Pymt Test	0	BondIssMeetPrvtSecPymtTestInd
Change In Use Bond Financed Prop	0	ChangeInUseBondFinancedPropInd
Procs Nonqualified Bond Remdtd	Yes (1)	ProcsNonqualifiedBondRemdtdInd

Tax Exempt Bonds Arbitrage TaxExemptBondsArbitrageGrp

Field	Value	IRS element (for citing)
Bond Reference	A	BondReferenceCd
Form8038 T Filed	0	Form8038TFiledInd
Rebate Not Due Yet	0	RebateNotDueYetInd
Exception To Rebate	0	ExceptionToRebateInd
No Rebate Due	Yes (1)	NoRebateDueInd
Variable Rate Issue	0	VariableRateIssueInd
Hedge Identified In Bks And Rec	0	HedgeIdentifiedInBksAndRecInd
Gross Proceeds Invested In GIC	0	GrossProceedsInvestedInGICInd
Gross Proceeds Invested	0	GrossProceedsInvestedInd
Written Proc To Monitor Reqs	Yes (1)	WrittenProcToMonitorReqsInd

Procedures Corrective Action ProceduresCorrectiveActionGrp

Field	Value	IRS element (for citing)
Bond Reference	A	BondReferenceCd
Procedures Corrective Action	Yes (1)	ProceduresCorrectiveActionInd

Supplemental Information Detail SupplementalInformationDetail (4 entries)

Form And Line ReferenceFormAndLineReferenceDesc	ExplanationExplanationTxt
DATE REBATE COMPUTATION PERFORMED	ISSUER NAME: CALIFORNIA INFRASTRUCTURE & ECONOMIC DEVELOPMENT BANK DATE THE REBATE COMPUTATION WAS PERFORMED: 06/29/2022
SCHEDULE K, PART I, BOND ISSUES:	(A) ISSUE NAME: CALIFORNIA INFRASTRUCTURE & ECONOMIC DEVELOPMENT BANK (F) DESCRIPTION ON PURPOSE: REFUND AND DEFEASE BONDS PREVIOUSLY ISSUED FOR THE BENEFIT OF THE INSTITUTE ON 06/29/2000 AND 02/23/2005.
SCHEDULE K, PART III, LINE 3D:	OVERALL PRIVATE USE ISN'T MATERIAL AND OUTSIDE COUNSEL WOULD REVIEW ANY SIGNIFICANT AGREEMENTS.
SCHEDULE K, PART IV, LINE 6:	THIS QUESTION IS BEING ANSWERED WITHOUT REGARD TO A YIELD-RESTRICTED ADVANCE REFUNDING ESCROW FINANCED WITH PROCEEDS OF THE BONDS.

Schedule M IRS990ScheduleM

Securities Publicly Traded SecuritiesPubliclyTradedGrp

Field	Value	IRS element (for citing)
Non Cash Checkbox	Yes (X)	NonCashCheckboxInd
Contribution	14	ContributionCnt
Noncash Contributions Rpt F990	$908,576	NoncashContributionsRptF990Amt
Method Of Determining Revenues	COST OR SELLING PRICE	MethodOfDeterminingRevenuesTxt

Field	Value	IRS element (for citing)
Form8283 Received	0	Form8283ReceivedCnt
Any Property That Must Be Held	0	AnyPropertyThatMustBeHeldInd
Review Process Unusual NC Gifts	Yes (1)	ReviewProcessUnusualNCGiftsInd
Third Parties Used	0	ThirdPartiesUsedInd

Supplemental Information Detail SupplementalInformationDetail

Field	Value	IRS element (for citing)
Form And Line Reference	PART I, COLUMN (B):	FormAndLineReferenceDesc
Explanation	NUMBER OF CONTRIBUTIONS OF PUBLICLY TRADED STOCK.	ExplanationTxt

Schedule N IRS990ScheduleN

Disposition Of Assets Detail DispositionOfAssetsDetail

Field	Value	IRS element (for citing)
Assets Distri Or Expnss Paid	PROPERTY, CASH, CASH EQUIVALENTS	AssetsDistriOrExpnssPaidDesc
Distribution	2022-04-01	DistributionDt
Fair Market Value Of Asset	$396,176,835	FairMarketValueOfAssetAmt
Method Of FMV Determination	APPRAISALS	MethodOfFMVDeterminationTxt
EIN	596002052	EIN

Business Name BusinessName

Field	Value	IRS element (for citing)
Business Name Line1	UNIVERSITY OF FLORIDA	BusinessNameLine1Txt

US Address USAddress

Field	Value	IRS element (for citing)
Address Line1	PO BOX 113201 STE 1250 EAS	AddressLine1Txt
City	GAINESVILLE	CityNm
State Abbreviation	FL	StateAbbreviationCd
ZIP	32611	ZIPCd

Field	Value	IRS element (for citing)
IRC Section	501(C)(3)	IRCSectionTxt

Field	Value	IRS element (for citing)
Director Of Successor2	0	DirectorOfSuccessor2Ind
Employee Of Successor2	Yes (1)	EmployeeOfSuccessor2Ind
Owner Of Successor2	0	OwnerOfSuccessor2Ind
Receive Compensation2	0	ReceiveCompensation2Ind

Supplemental Information Detail SupplementalInformationDetail (2 entries)

Form And Line ReferenceFormAndLineReferenceDesc

ExplanationExplanationTxt

PART II, LINE 2E:

EXPLANATION OF INVOLVEMENT: DOUGLAS A. BINGHAM, KEY EMPLOYEE, WAS HIRED BY THE TRANSFEREE ORGANIZATION.

PART II, LINE 1

SCRIPPS FLORIDA WAS ESTABLISHED IN JANUARY 2004 AS AN OPERATING DIVISION OF SCRIPPS RESEARCH WITH A PRIMARY FOCUS ON BASIC BIOMEDICAL RESEARCH AND DRUG DISCOVERY. SCRIPPS FLORIDA WAS OPERATED FROM 2004 THROUGH TO THE EFFECTIVE DATE OF THE ASSET TRANSFER AGREEMENT ENTERED INTO IN 2021, AND EFFECTIVE IN MARCH 2022. THIS ASSET TRANSFER AGREEMENT WAS ENTERED INTO BETWEEN SCRIPPS RESEARCH AND A THIRD-PARTY NOT-FOR-PROFIT ENTITY STATING THAT SCRIPPS RESEARCH WILL CONTRIBUTE ALL ITS ASSETS AND RELATED LIABILITIES FROM THE FLORIDA RESEARCH FACILITY TO THIS NOT-FOR-PROFIT ENTITY. A FAIR VALUE APPRAISAL OF THE FLORIDA ASSETS WAS OBTAINED, WHICH RESULTED IN A NET GAIN AND WRITE-UP OF ASSETS OF $142 MILLION RECORDED IN OTHER REVENUE AND SUPPORT AND A RESULTING CONTRIBUTION EXPENSE OF $396 MILLION WAS RECORDED IN CONTRIBUTION EXPENSE AND OTHER IN THE ACCOMPANYING STATEMENT OF ACTIVITIES. $88.2 MILLION OF THE TOTAL CONTRIBUTION EXPENSE WAS TRANSFERRED IN CASH. ALL ASSETS TRANSFERRED AT FAIR VALUE WERE CONSIDERED PART OF THE CONTRIBUTION EXPENSE.

Schedule O IRS990ScheduleO

Supplemental Information Detail SupplementalInformationDetail (6 entries)

Form And Line ReferenceFormAndLineReferenceDesc	ExplanationExplanationTxt
FORM 990, PART III, LINE 3	SCRIPPS FLORIDA WAS ESTABLISHED IN JANUARY 2004 AS AN OPERATING DIVISION OF SCRIPPS RESEARCH WITH A PRIMARY FOCUS ON BASIC BIOMEDICAL RESEARCH AND DRUG DISCOVERY. SCRIPPS FLORIDA WAS OPERATED FROM 2004 THROUGH TO THE EFFECTIVE DATE OF THE ASSET TRANSFER AGREEMENT ENTERED INTO IN 2021, AND EFFECTIVE IN MARCH 2022. THIS ASSET TRANSFER AGREEMENT WAS ENTERED INTO BETWEEN SCRIPPS RESEARCH AND A THIRD-PARTY NOT-FOR-PROFIT ENTITY STATING THAT SCRIPPS RESEARCH WILL CONTRIBUTE ALL ITS ASSETS AND RELATED LIABILITIES FROM THE FLORIDA RESEARCH FACILITY TO THIS NOT-FOR-PROFIT ENTITY. A FAIR VALUE APPRAISAL OF THE FLORIDA ASSETS WAS OBTAINED, WHICH RESULTED IN A NET GAIN AND WRITE-UP OF ASSETS OF $142 MILLION RECORDED IN OTHER REVENUE AND SUPPORT AND A RESULTING CONTRIBUTION EXPENSE OF $396 MILLION WAS RECORDED IN CONTRIBUTION EXPENSE AND OTHER IN THE ACCOMPANYING STATEMENT OF ACTIVITIES. $88.2 MILLION OF THE TOTAL CONTRIBUTION EXPENSE WAS TRANSFERRED IN CASH. ALL ASSETS TRANSFERRED AT FAIR VALUE WERE CONSIDERED PART OF THE CONTRIBUTION EXPENSE.
FORM 990, PART VI, SECTION B, LINE 11B	ON JUNE 30, 2023, THE AUDIT COMMITTEE REVIEWED A DRAFT OF THE FORM 990 (INCLUDING ALL SUPPLEMENTAL SCHEDULES). THIS REVIEW INCLUDED A PRESENTATION OF THE STATEMENTS BY THE STAFF WITH PARTICULAR EMPHASIS ON DISCLOSURES ABOUT GOVERNANCE AND ABOUT TRANSACTIONS WITH INTERESTED PERSONS. THE 990 WILL BE PROVIDED TO THE FULL BOARD OF DIRECTORS PRIOR TO FILING.
FORM 990, PART VI, SECTION B, LINE 12C	TSRI'S CONFLICT OF INTEREST POLICIES AND PROCEDURES APPLY TO MEMBERS OF THE BOARD OF DIRECTORS, OFFICERS, KEY PERSONNEL, AND THEIR FAMILY MEMBERS (ALTOGETHER COVERED INDIVIDUALS) TO PROTECT THE INTERESTS OF TSRI WHEN IT IS CONTEMPLATING ENTERING INTO A TRANSACTION OR ARRANGEMENT THAT COULD: 1) BENEFIT THE PRIVATE INTEREST OF A COVERED INDIVIDUAL WITHIN THE MEANING OF TREASURY REGULATION SECTION 1.501(C)(3)-1(D)(1)(II), 2) RESULT IN A POSSIBLE EXCESS BENEFIT TRANSACTION WITHIN THE MEANING OF SECTION 4958(C) OF THE INTERNAL REVENUE CODE OF 1986, AS AMENDED; OR 3) BE A SELF-DEALING TRANSACTION WITHIN THE MEANING OF SECTION 5233 OF THE CALIFORNIA CORPORATIONS CODE (THE "CORPORATIONS CODE"). TSRI'S POLICIES AND PROCEDURES ARE INTENDED TO SUPPLEMENT, BUT NOT REPLACE, ANY STATE AND FEDERAL LAWS GOVERNING ACTUAL, POTENTIAL, OR APPARENT CONFLICT OF INTEREST APPLICABLE TO TSRI. DISCLOSURE DOCUMENTS RESPONSIVE TO TSRI'S POLICIES ARE ANNUALLY SUBMITTED BY COVERED INDIVIDUALS, AND ARE REVIEWED BY TSRI ADMINISTRATION FOR PERTINENT RELATIONSHIPS. ANY TRANSACTIONS OR ARRANGEMENTS INVOLVING COVERED INDIVIDUALS THAT FALL WITHIN THE SCOPE OF THE POLICIES ARE THEN SUBJECT TO REVIEW AND CONSIDERATION BY NON-CONFLICTED BOARD OF DIRECTOR MEMBERS, WITH CONFLICTED MEMBERS BEING RECUSED FROM ANY DEBATE AND VOTE TO APPROVE OR DISAPPROVE.
FORM 990, PART VI, SECTION B, LINE 15	THE COMPENSATION OF THE CEO AND CERTAIN OTHER KEY EXECUTIVES WAS REVIEWED ON SEPTEMBER 28, 2021, AND APPROVED BY THE BOARD OF DIRECTORS. THIS REVIEW WAS BASED, IN PART, ON ANALYSIS PERFORMED BY THE HUMAN RESOURCES DEPARTMENT, AND INCLUDED DATA FROM OUTSIDE CONSULTANTS OR INTERNALLY-CONDUCTED RESEARCH. ON AN ONGOING BASIS, EXECUTIVES MAY PARTICIPATE IN THE NORMAL ANNUAL SALARY INCREASE PROGRAM, WHICH IS BASED ON A RECOMMENDATION FROM THE HUMAN RESOURCES DEPARTMENT BASED ON MARKET RESEARCH. ANY UNUSUAL OR POTENTIALLY NON-QUALIFIED COMPENSATION WOULD BE REVIEWED BY OUTSIDE COUNSEL FOR ANY TAX COMPLIANCE ISSUES.
FORM 990, PART VI, SECTION C, LINE 19	GOVERNING DOCUMENTS AND CONFLICT OF INTEREST POLICIES ARE NOT AVAILABLE TO THE PUBLIC AT THIS TIME. THE FINANCIAL STATEMENTS ARE PROVIDED TO BOND HOLDERS THROUGH TSRI'S DISSEMINATION AGENT. THE ANNUAL INFORMATION RETURN IS PROVIDED UPON REQUEST.
FORM 990, PART IX, LINE 11G	PURCHASED SERVICES AND MAINTENANCE: PROGRAM SERVICE EXPENSES 45,623,842. MANAGEMENT AND GENERAL EXPENSES 1,979,512. FUNDRAISING EXPENSES 1,129,433. TOTAL EXPENSES 48,732,787.

Schedule R IRS990ScheduleR

Id Disregarded Entities IdDisregardedEntitiesGrp

Disregarded Entity Name DisregardedEntityName

Field	Value	IRS element (for citing)
Business Name Line1	STRIDE LLC	BusinessNameLine1Txt

US Address USAddress

Field	Value	IRS element (for citing)
Address Line1	10550 NORTH TORREY PINES ROAD	AddressLine1Txt
City	LA JOLLA	CityNm
State Abbreviation	CA	StateAbbreviationCd
ZIP	92037	ZIPCd

Field	Value	IRS element (for citing)
EIN	825129385	EIN
Primary Activities	FACILITATE BASIC RESEARCH	PrimaryActivitiesTxt
Legal Domicile State	CA	LegalDomicileStateCd
Total Income	$105,470	TotalIncomeAmt
End Of Year Assets	$62,283	EndOfYearAssetsAmt

Direct Controlling Entity Name DirectControllingEntityName

Field	Value	IRS element (for citing)
Business Name Line1	THE SCRIPPS RESEARCH INSTITUTE	BusinessNameLine1Txt

Id Related Org Txbl Corp Tr IdRelatedOrgTxblCorpTrGrp (2 entries)

Address Line1USAddress/AddressLine1Txt	CityUSAddress/CityNm	State AbbreviationUSAddress/StateAbbreviationCd	ZIPUSAddress/ZIPCd	EINEIN	Primary ActivitiesPrimaryActivitiesTxt	Legal Domicile StateLegalDomicileStateCd	Business Name Line1DirectControllingEntityName/BusinessNameLine1Txt	Entity TypeEntityTypeTxt	Share Of Total IncomeShareOfTotalIncomeAmt	Share Of EOY AssetsShareOfEOYAssetsAmt	OwnershipOwnershipPct	Controlled OrganizationControlledOrganizationInd
CALM THERAPEUTICS INC
10550 NORTH TORREY PINES ROAD	LA JOLLA	CA	92037	825375039	RESEARCH	DE	THE SCRIPPS RESEARCH INSTITUTE	C	-$66,856	$105,023	0.62020	Yes (1)
BIOSURF INC
10550 NORTH TORREY PINES ROAD	LA JOLLA	CA	92037	825117568	RESEARCH	DE	THE SCRIPPS RESEARCH INSTITUTE	C	-$2,364		0.60600	Yes (1)

Field	Value	IRS element (for citing)
Receipt Of Int Annts Rnts Rylts	0	ReceiptOfIntAnntsRntsRyltsInd
Gift Grnt Or Cap Contri To Oth Org	0	GiftGrntOrCapContriToOthOrgInd
Gift Grnt Cap Contri From Oth Org	0	GiftGrntCapContriFromOthOrgInd
Loans Or Guarantees To Other Org	0	LoansOrGuaranteesToOtherOrgInd
Loans Or Guarantees From Oth Org	0	LoansOrGuaranteesFromOthOrgInd
Div Related Organization	0	DivRelatedOrganizationInd
Asset Sale To Other Org	0	AssetSaleToOtherOrgInd
Asset Purchase From Other Org	0	AssetPurchaseFromOtherOrgInd
Asset Exchange	0	AssetExchangeInd
Rental Of Facilities To Oth Org	0	RentalOfFacilitiesToOthOrgInd
Rental Of Fclts From Oth Org	0	RentalOfFcltsFromOthOrgInd
Perform Of Services For Oth Org	Yes (1)	PerformOfServicesForOthOrgInd
Perform Of Services By Other Org	0	PerformOfServicesByOtherOrgInd
Sharing Of Facilities	0	SharingOfFacilitiesInd
Paid Employees Sharing	Yes (1)	PaidEmployeesSharingInd
Reimbursement Paid To Other Org	0	ReimbursementPaidToOtherOrgInd
Reimbursement Paid By Other Org	0	ReimbursementPaidByOtherOrgInd
Transfer To Other Org	0	TransferToOtherOrgInd
Transfer From Other Org	0	TransferFromOtherOrgInd

Transactions Related Org TransactionsRelatedOrgGrp

Other Organization Name OtherOrganizationName

Field	Value	IRS element (for citing)
Business Name Line1	CALM THERAPEUTICS INC	BusinessNameLine1Txt

Field	Value	IRS element (for citing)
Transaction Type	L	TransactionTypeTxt
Involved	$167,753	InvolvedAmt
Method Of Amount Determination	CASH METHOD	MethodOfAmountDeterminationTxt